scholarly journals Specific micronutrient concentrations are associated with inflammatory cytokines in a rural population of Mexican women with a high prevalence of obesity

2012 ◽  
Vol 109 (4) ◽  
pp. 686-694 ◽  
Author(s):  
Gerardo Zavala ◽  
Kurt Z. Long ◽  
Olga P. García ◽  
María del Carmen Caamaño ◽  
Tania Aguilar ◽  
...  
Keyword(s):  
Rural Communities ◽  
Inflammatory Cytokines ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Reactive Protein ◽  
Tnf Α ◽  
High Prevalence ◽  
Prevalence Of Obesity

It has been recognised recently that obese individuals have lower concentrations of micronutrients and this may affect the concentrations of inflammatory cytokines. A cross-sectional study was carried out to evaluate the association of specific micronutrients' status with chronic inflammation caused by obesity in 280 women (36·1 (sd7·5) years) from seven rural communities in Mexico. Measurements of weight, height and waist circumference were made on all women and body composition was determined by dual-energy X-ray absorptiometry. Concentrations of the cytokines IL-1, TNF-α, IL-6, IL-10 and IL-12, lipid profile, and the micronutrients Zn and vitamins A, C and E were determined in fasting blood samples. Ordered logistic regression models were used to determine associations between categorised cytokine levels and micronutrients. It was found that 80 % of women were overweight or obese, and had significantly higher concentrations of C-reactive protein than normal-weight women (P= 0·05). The risk of higher levels of TNF-α, IL-6, IL-10 and IL-12 was reduced significantly among women with higher Zn concentrations (OR 0·63, 95 % CI 0·42, 0·96,P= 0·03; OR 0·57, 95 % CI 0·39, 0·86,P= 0·025; OR 0·63, 95 % CI 0·41, 0·96,P= 0·04; OR 0·62, 95 % CI 0·41, 0·95,P= 0·03, respectively). Higher concentrations of vitamin A were slightly associated with reduced risks of higher levels of IL-1 and IL-12 (OR 0·97, 95 % CI 0·95, 0·99,P= 0·03; OR 0·97, 95 % CI 0·94, 0·99,P= 0·03, respectively); when adjusting for BMI, this association was lost. No associations were found between vitamin C or vitamin E:lipids concentrations and inflammatory cytokines. In conclusion, higher Zn concentrations are associated with reduced risks of higher concentration of inflammation markers in a population of women with a high prevalence of obesity.

scholarly journals Are normal-weight adolescents satisfied with their weight?

2016 ◽  
Vol 134 (3) ◽  
pp. 219-227 ◽  
Author(s):  
Mariana Contiero San Martini ◽  
Daniela de Assumpção ◽  
Marilisa Berti de Azevedo Barros ◽  
Ana Maria Canesqui ◽  
Antonio de Azevedo Barros Filho
Keyword(s):  
Population Based ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Cross Sectional ◽  
High Prevalence ◽  
Health Related ◽  
Prevalence Of Obesity ◽  
The City ◽  
Prevalence Ratios ◽  
Domestic Appliances

ABSTRACT: CONTEXT AND OBJECTIVE: The high prevalence of obesity has led to public policies for combating it. People with normal weight may gain greater awareness of this issue and change their perceptions of their weight. The aim of this study was to evaluate the prevalence of body weight dissatisfaction among normal-weight adolescents, according to demographic and socioeconomic variables, health-related behavior and morbidities. DESIGN AND SETTING: Population-based cross-sectional study that used data from a health survey conducted in the city of Campinas, São Paulo, in 2008-2009. METHODS: The prevalence and prevalence ratios of weight dissatisfaction were estimated according to independent variables, by means of simple and multiple Poisson regression. RESULTS: 573 normal-weight adolescents aged 10 to 19 years (mean age 14.7 years) were analyzed. The prevalence of weight dissatisfaction was 43.7% (95% confidence interval, CI: 37.8-49.8). Higher prevalences of weight dissatisfaction were observed among females, individuals aged 15 to 19 years, those whose households had eight or more domestic appliances, former smokers, individuals who reported alcohol intake and those who had one or more chronic diseases. Lower prevalence of dissatisfaction was observed among adolescents living in substandard housing. Among the normal-weight adolescents, 26.1% wished to lose weight and 17.6% wished to gain weight. CONCLUSION: The results from this study indicate that even when weight is seen to be within the normal range, a high proportion of adolescents express dissatisfaction with their weight, especially females, older adolescents and those of higher socioeconomic level.

scholarly journals Evaluation of Nutritional Risk and Prevalence of Obesity in Patients with Covid-19 in A Reference Hospital in Salvador, Bahia, Brazil: A Cross-Sectional Study

2021 ◽  
Vol 14 (01) ◽  
pp. 011-015
Author(s):  
Rodrigo Fernandes Weyll Pimentel ◽  
Gilson Cruz de Moraes ◽  
Shalla Gomes Cavalcanti Barcelos ◽  
Pedro Carlos Muniz de Figueiredo ◽  
Magno Conceição Das Merces
Keyword(s):  
Cross Sectional Study ◽  
Nutritional Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
High Prevalence ◽  
Reference Hospital ◽  
Prevalence Of Obesity ◽  
Nrs 2002 ◽  
Study Type ◽  
Nutritional Risk Screening

Abstract Introduction The Coronavirus has spread to almost every country in the world, causing the coronavirus disease (COVID-19). The coronavirus stands out among the other infections especially by it's high contagious power and important effects on the respiratory system. The COVID-19 has differents ways of presentation and these are influenced by the patient's previous nutricional status, correlated with the patient's lifestyle and comorbities. Objective this survey seeks to analyze the nutritional status and the prevalence of obesity in patients hospitalized with SARS-CoV-2. Methods: this is a descriptive, prospective and cross-sectional study type, which 41 patients affected by COVID-19 were interviewed. Patient's weight and height were used to assess the BMI, and nutritional risk assessment was performed using the Nutritional Risk Screening tool (NRS 2002). For the analysis, Absolute (AF) and Relative Frequency (RF), the mean and the standard deviation were calculated. Results It was observerd that 78% of the participants had a high nutritional risk, while only 22% had a low nutritional risk. Besides that, 34% showed overweight and 41.4% showed obesity. Conclusion the existence of a high prevalence of increased nutritional risk was evidenced, in addition to the high frequency of overweight in patients affected by SARS-CoV-2.

scholarly journals Factors associated with uremic pruritus

10.3823/2448 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Mariele Gobo-Oliveira ◽  
Vitoria G Pigari ◽  
Matheus S.P. Ogata ◽  
Hélio A. Miot ◽  
Daniela Ponce ◽  
...  
Keyword(s):  
Associated Factors ◽  
Public Hospital ◽  
Statistical Significance ◽  
Cross Sectional Study ◽  
High Flux ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Uremic Pruritus ◽  
Reactive Protein ◽  
High Prevalence

Background: The etiopathogenesis of uremic pruritus (UP) is multifactorial aspect, and it is thus necessary to elucidate its associated factors to develop efficient therapeutics approaches. This study aimed to verify the prevalence of UP and its associated factors. Methods and Findings: Prospective and cross-sectional study with patients undergoing hemodialysis at a university public hospital. The data were obtained between April 2014 and April 2015. The statistical analysis was carried out using multivariate regression models, and statistical significance was set at p<0.05. A total of 164 patients were included, and pruritus was reported in 64 (39%). In the multivariate analysis, a higher creatinine level was risk factor for pruritus (β=1.09, 95% CI 1.00-1.19; p=0.048), as was a lower level of hemoglobin (β=0.85, 95% CI 0.73-0.99; p=0.043). Dyslipidemia (β=1.52, 95% CI 0.12-2.91; p=0.03), obesity (β=2.40, 95% CI 1.03-3.78; p=0.001), higher levels of C-reactive protein (β=0.26, 95% CI 0.19-0.34; p<0.001) and black race (β=1.49, 95% CI -2.57 and 0.42; p<0.006) were associated with a greater intensity of pruritus. The use of a high-flux dialyzer was associated with a lower intensity of pruritus (β=-1.69, 95% CI -3.05-0.34; p=0.01). Conclusion: Uremic pruritus has a high prevalence in hemodialysis patients, and the data suggest that the higher the creatinine and the lower the hemoglobin levels are, the greater the risk of developing pruritus is. Dyslipidemia, obesity, and higher levels of C-reactive protein were associated with a greater intensity of pruritus, whereas the use of a high-flux dialyzer was associated with lower pruritus intensity.

scholarly journals Correlation between Circulating Levels of Pro-Inflammatory Cytokines TNF-alpha and Vascular Calcification Inhibitor Matrix Gla Protein in Obese Men

2010 ◽  
Vol 2 (3) ◽  
pp. 126
Author(s):  
Trilis Yulianti ◽  
Mansyur Arif ◽  
Andi Wijaya
Keyword(s):  
Vascular Calcification ◽  
Inflammatory Cytokines ◽  
Univariate Analysis ◽  
Cross Sectional Study ◽  
Matrix Gla Protein ◽  
Sectional Study ◽  
Cross Sectional ◽  
Tnf Α ◽  
Circulating Levels ◽  
Pro Inflammatory Cytokines

BACKGROUND: Adult obesity is rapidly increasing in the world including Indonesia. Tumor necrosis factor α (TNF-α) was chronically elevated in obese adipose tissue. TNF-α, a pleiotropic cytokine and also a regulator of bone formation, may might represent an important link between obesity and vascular calcification. Elegant genetic studies in mice and human have highlighted the important roles for Matrix Gla Protein (MGP) as an inhibitor of vascular calcification. The aim of this study was to examine the correlation between circulating levels of pro-inflammatory cytokines TNF-α and vascular calcification inhibitor MGP in obese men.METHODS: This was an observational cross-sectional study including 40 central obese men (waist circumference ≥90 cm) aged 31-60 years old. Serum MGP and serum TNF-α concentrations were quantified by ELISA principle. Fasting plasma glucose was assessed using hexokinase methods, triglyceride by GPO-PAP methods, and creatinine by Jaffe methods. All assays were performed according to the manufacture instruction. Statistical analysis was performed with SPSS for windows ver 16. Univariate analysis were performed to analyze mean, maximum, minimum value and SD. Pearson correlation statistic were performed to determine the correlation between variables. Significance value were define as alpha level = 0.05 based on two-tailed tests.RESULTS: The cross-sectional study (n=40) showed that the advancing age was correlated with plasma TNF-α concentration (r=0.348; p=0.028). The mean concentration of TNF-α and MGP were 8.323 and 8.368, respectively. We found a significant negative correlation between TNF-α with MGP (r=-0.425; p=0.006) and a significant correlation between TNF-α and triglyceride (r=0.375; p=0.017).CONCLUSIONS: Circulating level of TNF-α was inversely correlated with MGP concentration in obese men. This finding suggested that high level TNF-α leads to low MGP concentration obese men, hence, limits inhibitory capacity in vascular calcification.KEYWORDS: hypertension, obesity, vascular calcification, MGP, TNF-α

scholarly journals A community based study on prevalence of obesity among urban population of Shivamogga, Karnataka, India

2016 ◽  
Vol 4 (1) ◽  
pp. 96 ◽  
Author(s):  
Kanchana Nagendra ◽  
Nandini C. ◽  
Mangala Belur
Keyword(s):  
Urban Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Obesity And Overweight ◽  
Study Results ◽  
High Prevalence ◽  
Prevalence Of Obesity ◽  
Who Steps

Background: Obesity is a most prevalent malnutrition all over the world. It is estimated by the WHO that globally, over 1 billion (16%) adults are overweight and 300 million of these (5%) are obese. The highest rise in the number of obese is noted in the countries with fast growing economies especially of South East Asia. In India the prevalence of obesity is 12.6% in women and 9.3% in men. In other words, more than a 100 million individuals are obese in India. Objectives: To assess the prevalence of obesity in urban population of Shivamogga.Methods:A cross sectional study was conducted in Urban Shivamogga Study was conducted during February 1st to July 30th 2016 for 6 months.  Data was collected from house hold members aged 15-64 years. The calculated sample size was 2000. Subjects were interviewed using a prestructured and pretested questionnaire adopted from WHO STEPS I and II, approaches for non-communicable diseases risk factors surveillance, after modifying to suit the local requirements (questions about Obesity and overweight were considered for study).Results: The prevalence of high BMI among study subjects was nearly fifty percent (45.6%).  The prevalence of obesity in the study subjects was 31.6%, the prevalence was more in females (34.9%) compared to males (28.4%). The prevalence of central/ abdominal type of obesity was 41.2%.Conclusions:This community based study demonstrated high prevalence of obesity and overweight among the productive population of urban Shivamogga. 

scholarly journals High plasma salivary α-amylase, but not high AMY1 copy number, associated with low obesity rate in Qatari adults: cross-sectional study

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Neyla Al-Akl ◽  
Richard I. Thompson ◽  
Abdelilah Arredouani
Keyword(s):  
Copy Number ◽  
High Plasma ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Whole Genome Sequencing Data ◽  
Obesity Prevalence ◽  
Sequencing Data ◽  
Cross Sectional ◽  
Prevalence Of Obesity ◽  
The Relationship

Abstract The relationship between salivary α-amylase activity (psAAa) or AMY1 copy number and the risk of obesity remains controversial. We aimed to assess this relationship in a cohort from Qatar, where obesity affects 43% of adults. The relationship was investigated cross-sectionally in 923 Qatari adults from the Qatar biobank cohort. AMY1 CN was estimated form whole genome sequencing data. The associations with obesity prevalence were assessed by linear and logistic regressions. We found no difference in AMY1 CN between obese and normal-weight individuals. However, the psAAa was significantly lower in obese individuals. Significant inverse correlations were found between adiposity markers and psAAa in both sexes, but were marginally stronger in men. A significant effect of high psAAa, but not AMY1 CN, on reduced obesity rates was identified in men (OR per psAAa unit 0.957 [95% CI 0.937–0.977], p < 0.001, with psAAa ranging between 5 to 66 U/L). A significantly higher prevalence of obesity was observed in the lowest quartile of psAAa in men (75% (Q1) vs. 36% (Q4), p < 0.001) and women (74% (Q1) vs 56% (Q4), p = 0.009). Our findings suggest that high psAAa, but not AMY1 CN, has a potential positive benefit against obesity in the Qatari population.

Body mass index and its relationship with body composition in a population of university students in the state of Mexico

2019 ◽  
pp. 17-22
Author(s):  
Raquel Muñoz-Hernández ◽  
Saúl Rangel Lara ◽  
Enrique Nava Zavala
Keyword(s):  
Body Composition ◽  
University Students ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
The State ◽  
Cross Sectional ◽  
Prevalence Of Obesity ◽  
The University

This research was carried out with the objective of determining the association between excess weight and body composition in university students. It is an observational cross-sectional study in a public university of the State of Mexico; 64 students between 19 and 25 years old were included through a simple random sampling. Body composition was assessed based on Anthropometry with written acceptance. The results when analyzing the central obesity in the population showed that 57.81% are normal weight, 29.69% are overweight and 7.81% are obese. Also 50% of men between 20-25 years, have values ≥90 cm waist. In the case of women, the prevalence of a value above that recommended ≥80 cm was greater than 55% since the age of 19. This result indicates that most women are at greater risk from an early age. These preliminary results show how the university population reflects the high rates of overweight and obesity in Mexico. It is necessary to establish plans to prevent and reduce the prevalence of obesity and avoid its impact on chronic diseases in the future.

scholarly journals Insulin Resistance and Cardiovascular Risks in Different Groups of Hemodialysis Patients: A Multicenter Study

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Tuyen Van Duong ◽  
Chun-Kuang Shih ◽  
Te-Chih Wong ◽  
Hsi-Hsien Chen ◽  
Tso-Hsiao Chen ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Normal Weight ◽  
Cardiovascular Risks ◽  
Cross Sectional ◽  
High Systolic Blood Pressure ◽  
Reactive Protein ◽  
High Triglyceride

Background. To investigate the association between insulin resistance (IR) and cardiovascular disease (CVD) risks among hemodialysis patients. Methods. We conducted a cross-sectional study between 2013 and 2017, on 384 hemodialysis patients from seven hospital-based-dialysis centers. HOMA-IR is classified according to median value. The CVD risks were defined by the K/DOQI Guidelines. Logistic regression analysis was used. Results. Patients’ age was 60.9 ± 11.8, 58.1% men, and 40.3% overweight/obese. The median of HOMA-IR was 5.4, 82.8% high systolic blood pressure, and 85.7% hyperhomocysteinemia. In multivariate analysis, IR was significantly associated with higher odds of low high-density lipoprotein cholesterol, high triglyceride, and impaired fasting glucose in groups of normal weight, overweight/obese, nondiabetes, diabetes, and overall sample. IR linked with elevated high-sensitive C-reactive protein in normal weight patients (odd ratio, OR=2.21, 95% confidence interval, 1.16-4.22, p < .05), with hypoalbuminemia in normal weight patients (OR=8.31, 95% CI, 2.35-29.37, p < .01), in nondiabetes patients (OR=6.59, 95% CI, 1.81-23.95, p < .01), and overall sample (OR=3.07, 1.51-6.23, p < .01). Conclusions. The level of IR and prevalence of CVD risks were high in hemodialysis patients. IR was independently associated with CVD risks.

scholarly journals Analysis of Body Composition of 9- and 10-Year-Old Children in Latvia

Medicina ◽  
2011 ◽  
Vol 47 (10) ◽  
pp. 82
Author(s):  
Helena Karklina ◽  
Peteris Apinis ◽  
Liga Kalnina ◽  
Melita Sauka ◽  
Dzintars Mozgis ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Pediatric Population ◽  
Cross Sectional Study ◽  
Physical Development ◽  
Normal Weight ◽  
Overweight And Obesity ◽  
Cross Sectional ◽  
High Prevalence ◽  
Nutritional Level

Background and Objective. According to the data of epidemiologic research, the prevalence of both excessive and insufficient body weight is increasing in a pediatric population leading to the growing burden of health problems due to these changes. The aim of the study was to understand the current situation of physical development of 9- and 10-year-old boys and girls in Latvia and to estimate the prevalence of underweight, normal weight, overweight, and obesity among young adolescents. Material and Methods. During 2007–2009, a random sample of healthy 9-year-old (n=184) and 10-year-old (n=320) children from all regions and different socioeconomic groups of Latvia was surveyed in a cross-sectional study. The anthropometric measurements of height, weight, 3 circumferences, and 5 skinfolds were performed. The percentage of body fat was calculated by the equation of Slaughter et al. Body mass index and fat mass index were calculated for each respondent. Children were divided into groups according to these indexes. At the age of 9 years, 69.5% of boys had a normal nutritional level either by BMI or FMI, and 54.5% and 72.2% of the girls of the same age had a normal nutritional level by BMI and by FMI, respectively. Obesity according to BMI in 9-year-old boys was found to be 4.7% and in girls 6.1%; according to FMI, 3.7% and 2.3%, respectively. A similar trend was also observed in the cohort of 10-year-old children. Conclusions. The results of the research showed that the problem of high prevalence of Latvian children with underweight is not smaller than the problem of children with obesity. Evaluation of physical development in children based only body mass index may lead to overdiagnosis of obesity.

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