Acute effect of smoking on rebreathing carbon monoxide, breath-hold carbon monoxide and alveolar oxygen

1988 ◽  
Vol 75 (4) ◽  
pp. 371-373
Author(s):  
Andrew J. T. Kirkham ◽  
Andrew R. Guyatt ◽  
Gordon Cumming

1. The rise (‘boost’) in carboxyhaemoglobin (HbCO) on smoking has been studied with alveolar carbon monoxide measurements before and after smoking a cigarette. We re-examined this in 28 subjects with HbCO values compared with rebreathing carbon monoxide [FAco(Rb)] and breath-hold alveolar carbon monoxide and oxygen concentrations, obtained after a 20 s breath-hold [FAco(Bh)] and FAo2(Bh), respectively]. Tests were done in the order FAco(Bh) and FAo2(Bh), FAco(Rb), FAco(Bh) and FAo2(Bh) before and after smoking a single cigarette, with HbCO being measured 1 min before and after smoking. 2. The changes were expressed as the relative boost: For HbCO the average value was 23.7%, but the FAco(Rb) boost was only 9.8%. The first post-smoking FAco(Bh) boost was 3.9% (5.0 min after smoking), rising to 8.5% 9.4 min later. 3. The FAo2(Bh) values fell from a mean of 15.4% before smoking to 14.3% (5.0 min after smoking) then recovered to 15.4% 9.4 min later, suggesting a transient effect on pulmonary gas exchange. Correction of the first post-smoke FAco(Bh) data for this effect increased the relative boost to 11.5%. Routine FAo2(Bh) measurements may be useful in further smoking studies. 4. We conclude that none of the alveolar sampling techniques gives a reliable measurement of the acute HbCO changes associated with smoking.

2019 ◽  
Vol 6 (1) ◽  
pp. 13
Author(s):  
Veny Mayasari ◽  
Liliana Liliana ◽  
Agung Anggoro Seto

<p><em>This research aims to find out the impact of business incubator activities against the interests of student entrepreneurship at the University of Tridinanti. This type of research is comparative</em><em>. </em><em>The population </em><em>are </em><em>5,737 people. Sampling techniques using Accidental sampling by the number of samples was determined as many as 200 respondents. The primary data sources with the techniques of data collection using the questionnaire, interview and observation. Data analysis techniques using paired sample t test. The results showed that there is a difference of interest a student entrepreneurship before and after follow the business incubator activities with significance value of 0.000 where the average value of interest in entrepreneurship student business incubator activities after following increased by 1.960 point than before following the activities of the business incubator. The research also found that business incubator activities have changed the mindset of most college students.</em></p>


Kappa Journal ◽  
2021 ◽  
Vol 5 (1) ◽  
pp. 109-119
Author(s):  
Resto Reswanto ◽  
◽  
Hadma Yuliani ◽  
Nur Inayah Syar ◽  
◽  
...  

This study was based on the lack of student learning outcomes due to the low variation in the learning model. This study aims to examine (1) Management of learning using inkuiri learning model guided in newton law material class X. (2) Significant influence before and after the implementation of the inkuiri learning model is guided to the learning outcomes in newton law material class X. This research uses quantitative approach and this type of research uses Pre-Experimental design in this design there is no control group to compare with the experimental group and with "One Group Pretest – Posttest Design". Instruments used in the form of observation sheets of learning management, tests of cognitive learning results, observation sheets affective and psychomotor. The population in this study took grade X science students in semester 2 at MA Muslimat NU Palangkaraya by sampling using saturation sampling techniques or saturated samples then the entire population was sampled. The results showed that (1) The management of learning using inquiri guided with an average value of 3.4 is quite good status. (2) The influence of guided inquiri learning models on learning outcomes with a significant value of 0.00 < 0.05.


1960 ◽  
Vol XXXIII (III) ◽  
pp. 417-427 ◽  
Author(s):  
John Kristoffersen

ABSTRACT By means of chromatographic and spectrophotometric methods progesterone and a substance closely similar to 20β-hydroxy-pregn-4-ene-3-one has been detected in luteal tissue from non-pregnant and pregnant cows. In 21 animals quantitative measurements based on a method giving an average net recovery of 56 per cent showed that in pregnancy the average progesterone content in the corpus luteum reached a maximum in the third to fifth month, with low values before and after this period. For 6 nonpregnant cows, the average value was 20.2 μg/g tissue, which is considerably higher than previous values reported in the literature. The relation between these findings and the bovine dependence on a functional corpus luteum in pregnancy is discussed, and it is pointed out that more information about the metabolism of progesterone in cattle is highly desirable.


2021 ◽  
Vol 17 ◽  
Author(s):  
Siyamak Shahab ◽  
Masoome Sheikhi ◽  
Mehrnoosh Khaleghian ◽  
Marina Murashko ◽  
Mahin Ahmadianarog ◽  
...  

: For the first time in the present study, the non-bonded interaction of the Coniine (C8H17N) with carbon monoxide (CO) was investigated by density functional theory (DFT/M062X/6-311+G*) in the gas phase and solvent water. The adsorption of the CO over C8H17N was affected on the electronic properties such as EHOMO, ELUMO, the energy gap between LUMO and HOMO, global hardness. Furthermore, chemical shift tensors and natural charge of the C8H17N and complex C8H17N/CO were determined and discussed. According to the natural bond orbital (NBO) results, the molecule C8H17N and CO play as both electron donor and acceptor at the complex C8H17N/CO in the gas phase and solvent water. On the other hand, the charge transfer is occurred between the bonding, antibonding or nonbonding orbitals in two molecules C8H17N and CO. We have also investigated the charge distribution for the complex C8H17N/CO by molecular electrostatic potential (MEP) calculations using the M062X/6-311+G* level of theory. The electronic spectra of the C8H17N and complex C8H17N/CO were calculated by time dependent DFT (TD-DFT) for investigation of the maximum wavelength value of the C8H17N before and after the non-bonded interaction with the CO in the gas phase and solvent water. Therefore, C8H17N can be used as strong absorbers for air purification and reduce environmental pollution.


2019 ◽  
Vol 28 (e1) ◽  
pp. e37-e42 ◽  
Author(s):  
Wasim Maziak ◽  
Ziyad Ben Taleb ◽  
Mohammad Ebrahimi Kalan ◽  
Thomas Eissenberg ◽  
James Thrasher ◽  
...  

ObjectivesThis study examined the effect of pictorial health warning labels (HWLs) on the waterpipe (WP) device on smokers’ experience, puffing behaviour, harm perception and exposure to respiratory toxicants.MethodsThirty WP smokers completed two 45 min ad libitum smoking sessions (WP without HWL vs WP with HWL) in a crossover design study. Exhaled carbon monoxide (eCO) was measured before and after each smoking session. Puff topography was recorded throughout the smoking session, and participants completed survey questionnaires assessing subjective smoking experiences and harm perception.ResultsSignificant differences were observed in eCO levels between the two study conditions, with lower levels of eCO boost recorded following smoking the WP fitted with HWL (16 ppm) compared with WP without HWL (22.7 ppm). Participants had more puffs, shorter interpuff intervals and a higher total puff volume during smoking the WP without HWL relative to WP with HWL (p values <0.05). We documented enhanced reports of satisfaction, taste and puff liking following smoking the WP without HWL compared with the WP with HWL. WP harm perception was significantly higher among participants after smoking the WP with HWL compared with WP without HWL.ConclusionThis pilot study shows that placing HWL on the WP device is effective in reducing WP smoker’s positive experiences, puffing parameters and exposure to carbon monoxide. HWLs lead also to more appreciation of WP harmful effects, making them a promising regulatory approach for addressing the spread of WP smoking among young adults in the USA.


2010 ◽  
Vol 28 (3) ◽  
pp. 115-119 ◽  
Author(s):  
Anaflávia O Freire ◽  
Gisele C M Sugai ◽  
Sônia Maria Togeiro ◽  
Luiz Eugênio Mello ◽  
Sérgio Tufik

Background Most patients with obstructive sleep apnoea (OSA) do not tolerate treatment with nasal continuous positive airway pressure, the ‘gold standard’ treatment for this condition. It was shown in a pilot study that acupuncture was more effective than placebo treatment (sham acupuncture) in producing significant changes in the respiratory events assessed by polysomnography (PSG). Objectives To investigate the immediate effect of manual acupuncture (MA) and electroacupuncture (EA) on the sleep pattern of patients presenting with moderate OSA. Methods 40 patients with an Apnoea–Hypopnoea Index (AHI) of 15–30/h were randomly allocated to MA treatment (n=10), EA 10 Hz treatment (n=10), EA 2 Hz treatment (n=10) and a no-treatment control group (n=10). The patients received MA or EA (2 or 10 Hz) just before the PSG study at 20:00. Results The AHI (p=0.005; p=0.005), the Apnoea Index (p=0.038; p=0.009) and the respiratory events (p=0.039; p=0.014) decreased significantly in the MA and EA 10 Hz groups, respectively (AHI (21.9, 11.2), Apnoea Index (5.15, 0.7), respiratory events (120.5, 61.0) in the MA group before and after. AHI (20.6, 9.9), Apnoea Index (8.2, 0.3), respiratory events (117.0, 56.0) in the EA 10 Hz group before and after). The micro-arousals decreased only in the MA group (146.0 vs 88.5, p=0.0002). There were no significant changes in the EA 2 Hz group or in the control group. Conclusion A single session of either MA or EA 10 Hz had an acute effect in reducing the AHI as well as the number of nocturnal respiratory events of patients presenting with moderate OSA.


2021 ◽  
Vol 13 (5) ◽  
pp. 919
Author(s):  
Marco Gabella

A previous study has used the stable and peculiar echoes backscattered by a single “bright scatterer” (BS) during five winter days to characterize the hardware of C-band, the dual-polarization radar located at Monte Lema (1625 m altitude) in Southern Switzerland. The BS is the 90 m tall metallic tower on Cimetta (1633 m altitude, 18 km range). In this note, the statistics of the echoes from the BS were derived from other ten dry days with normal propagation conditions in winter 2015 and January 2019. The study confirms that spectral signatures, such as spectrum width, wideband noise and Doppler velocity, were persistently stable. Regarding the polarimetric signatures, the large values (with small dispersion) of the copolar correlation coefficient between horizontal and vertical polarization were also confirmed: the average value was 0.9961 (0.9982) in winter 2015 (January 2019); the daily standard deviations were very small, ranging from 0.0007 to 0.0030. The dispersion of the differential phase shift was also confirmed to be quite small: the daily standard deviation ranged from a minimum of 2.5° to a maximum of 5.3°. Radar reflectivities in both polarizations were typically around 80 dBz and were confirmed to be among the largest values observed in the surveillance volume of the Monte Lema radar. Finally, another recent 5-day data set from January 2020 was analyzed after the replacement of the radar calibration unit that includes low noise amplifiers: these five days show poorer characteristics of the polarimetric signatures and a few outliers affecting the spectral signatures. It was shown that the “historical” polarimetric and spectral signatures of a bright scatterer could represent a benchmark for an in-depth comparison after hardware replacements.


Author(s):  
Т.Г. КОРОТКОВА ◽  
А.С. ДАНИЛЬЧЕНКО ◽  
Н.Ю. ИСТОШИНА

Исследована кинетика сушки сырой пивной дробины – вторичного продукта ООО «Белореченский пивоваренный завод» (Россия, Краснодарский край). Сушка проведена в двух температурных режимах – 60 и 55°С. Скорость сушильного агента при вынужденной конвекции составляла 4,5 м/с. Содержание сухого вещества определено по ГОСТ 31640–2012 в лабораторных условиях и составило 12,9%. Измерение убыли массы при сушке проведено с интервалом 5 мин. Общее время сушки навески пивной дробины в количестве 50 г – 420 мин при режиме 50°С, 360 мин – при 60°С. Среднее значение конечной влажности пивной дробины составило 11,85%. Построены кривые сушки и скорости сушки. Скорость сушки при удалении свободной влаги в первом периоде сушки, мин–1: при 60°С – 3,5, при 55°С – 3,0. Установлено, что содержание связанной влаги составляет в среднем 57% от массы влаги в навеске пивной дробины, свободной влаги – 43%. Анализ структуры навески пивной дробины под микроскопом до сушки и после нее подтвердил факт, что в исследованном материале количество связанной влаги больше, чем свободной. Наличие частиц размером 5–7 мм свидетельствует о значительном количестве клеточной влаги в неразрушенных капиллярах. Дальнейшее совершенствование технологии переработки пивной дробины должно быть направлено на разрушение клеточной структуры материала после его механического обезвоживания. The kinetics of drying of the crude brewer’s spent grain – a secondary product of LLC «Belorechensky brewery» (Russian Federation, Krasnodarregion) has been studied. Drying is carried out in two temperature modes – 60 and 55°C. The speed of the drying agent under forced convection was 4,5 m/s. The dry matter content was determined according to GOST 31640–2012 in laboratory conditions and was 12,9%. Measurement of mass loss during drying was performed at an interval of 5 min. The total drying time of the brewer’s spent grain sample in the amount of 50 gis 420 min at 50°C, 360 min – at 60°C. The average value of the final moisture content of brewer’s spent grain made up 11,85%. Curves of drying and drying speed are constructed. Drying speed when removing free moisture in the first drying period, min–1: at 60°C – 3,5, at 55°C – 3,0. It was found that the content on average of bound moisture is 57% of the mass of moisture in brewer’s spent grain, free moisture – 43%. Analysis of the structure sample of brewer’s spent grain a microscope before and after drying confirmed the fact that the amount of bound moisture in the studied material is greater than the amount of free moisture. The presence of particles of 5–7 mm in size indicates a significant amount of cellular moisture in undisturbed capillaries. Further improvement of the technology for processing brewer’s spent grain should be aimed at destroying the cellular structure of the material after its mechanical dehydration.


Author(s):  
M. Yu. Tashmetov ◽  
F. K. Khallokov ◽  
N. B. Ismatov ◽  
I. I. Yuldashova ◽  
S. Kh. Umarov

It is shown that the replacement of a part of sulfur atoms with selenium atoms in a TlInS2 single crystal stimulates the formation of a single-phase state with a monoclinic structure (space group [Formula: see text]/[Formula: see text] in TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]). Irradiation with 2 MeV electrons and a fluence of [Formula: see text] electron/cm2 of powder TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]) leads to an increase in the crystallite size from 56.5 nm to 65 nm, which is most likely associated with a decrease in the interface. The difference between the surface morphology of the synthesized TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]) single crystal and the surface morphology of the TlInS2 single crystal is established, which consists in a decrease in the height and width of the roughness in TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]). Irradiation of a TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]) single crystal with electrons with a fluence of [Formula: see text] electron/cm2 does not lead to a change in the height of the tubercle on its surface, and the average value of its width increases more than ten-fold. The identity of the peaks in the Raman spectra of the TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]) single crystal before and after its irradiation with electrons with an energy of 2 MeV and upto a fluence of [Formula: see text] electron/cm2, along with the absence of a shift of the peaks, indicates the radiation resistance of the TlInS[Formula: see text]Se[Formula: see text] ([Formula: see text]) single crystal.


2020 ◽  
Vol 4 (2) ◽  
pp. 231-239
Author(s):  
Animar Animar ◽  

The spread of the Corona virus has had a significant impact on the world of education. The policy taken by many countries, including Indonesia, is to close all educational activities. This makes the government and related institutions have to present an alternative learning process. Many factors affect student learning outcomes coupled with changes in learning conditions due to the Corona virus (Covid-19) outbreak. The purpose of this study was to obtain information about the impacts and constraints of the Covid-19 outbreak on teaching and learning activities, especially in Geography subjects at SMA Negeri 1 Sikur. Data collection was carried out using the pretest - posttest method of students' abilities before and after the Covid-19 pandemic. Furthermore, data analysis was carried out by quantitative methods using paired sample t-test to test the difference in the effect of the two treatments on the interrelated sample groups. The results of the analysis indicate that there is a difference in the average Geography learning outcomes of 11th grade of social science students before and after the outbreak of the corona virus. Information was obtained that the average value of student learning outcomes during the face-to-face learning process was 86.27, better than the average value when the learning process was carried out online which was 75.73. Keywords: covid-19 impact, learning outcomes, geography


Sign in / Sign up

Export Citation Format

Share Document