scholarly journals Effect of Adding Water-Soluble Chitosan on Some Physiological Traits of Quail Males

2021 ◽  
Vol 910 (1) ◽  
pp. 012082
Author(s):  
Samah Maiser Raouf ◽  
Ammar Salah aldeen Abdulwahid ◽  
Ahmed Abed allaw
Keyword(s):  
Enzymatic Activity ◽  
Protein Concentration ◽  
Water Soluble ◽  
Control Treatment ◽  
Control Group ◽  
Meat Production ◽  
Productive Performance ◽  
Total Protein Concentration ◽  
Treatment Control ◽  
Biochemical Traits

Abstract The study was conducted to determine the effect of adding water-soluble chitosan on some hematological and biochemical traits in the quail during rearing for meat production, twenty-seven male quail at nine weeks of age were randomly assigned to three treatments with three replicates, it was treated with chitosan for 28 days, according to the following concentrations, the first treatment (control treatment), the second and third treatments, water-soluble chitosan was added at a concentration of 0.2 and 0.3 g/L, respectively. The results showed that there were no significant differences among treatments in RBC, PCV, Hb, MCV, MCH, glucose concentration and AST and ALT enzymatic activity, while there were significantly increased WBC in both experimentsin addition treatments compared to the control treatment. The adding of the water-soluble chitosan at a concentration of 0.2 and 0.3 g/L resulted in a significant decrease in the concentration of cholesterol and triglycerides, while the adding 0.3 g/Lled to a significant increase (P≤ 0.05) in the total protein concentration, albumin and Globulin compared with the control group. We conclude from this research that the adding of water-soluble chitosan at a concentration of 0.3 g/L has the potential to improve productive performance and enhance bird health.

scholarly journals Efficacy of manganese pantothenate and lysinate chelates for prevention of perosis in broiler chickens

2021 ◽  
Vol 12 (2) ◽  
pp. 289-293
Author(s):  
V. S. Sakara ◽  
A. Y. Melnyk ◽  
V. V. Sakhniuk ◽  
N. V. Vovkotrub ◽  
M. M. Fedorchenko ◽  
...  
Keyword(s):  
Broiler Chickens ◽  
Protein Concentration ◽  
Mineral Metabolism ◽  
The Body ◽  
Clinical State ◽  
Control Group ◽  
Meat Production ◽  
Standard Diet ◽  
Meat Productivity ◽  
Reduced Mobility

Perosis is a common metabolic disease of industrial birds, especially broiler chickens. It leads to a violation of the balance of biotic substances in the body of chickens, which is clinically manifested by the curvature of the limbs, reduced mobility, and, consequently, reduced profitability of meat production. Prevention of perosis is possible provided that chickens receive a sufficient amount of manganese in a biologically available form. Studies were conducted to determine the efficiency of use of manganese chelates (pantothenate and lysinate) for prevention of perosis in broiler chickens. Efficacy was confirmed by examining changes in the clinical state, indicators of protein and mineral metabolism, as well as meat productivity of birds. For the experiment, broiler chickens of the Cobb-500 cross were taken at the age of 14 days. The birds of the control group received a standard diet, and the chickens from two experimental groups additionally received manganese pantothenate and lysinate with water during the critical period for the development of perosis – 14–28 days old. After 14 days of administration of manganese pantothenate and lysinate, the weight of the experimental birds at the age of 28 days was greater by 133.6 g (+11.0%) and 142.2 g (+11.7%), respectively, in comparison with poultry of the control group. Additional provision of manganese pantothenate and lysinate to chickens of the experimental groups contributed to an increase in the blood serum total protein concentration by 11.0% and 12.8 %, albumin – by 10.1% and 8.2%, magnesium – by 8.1% and 9.0% and manganese – by 29.6% and 26.9%, respectively, compared with indicies of the control group birds. The use of manganese chelates in the form of pantothenate (0.2 mL/L of water) and a lysinate (0.5 mL/L) during the 14–28th days of broiler chickens’ rearing provides 100% prevention of perosis. This reduces the death of broiler chickens, increases body weight, and, as a result, significantly increases the profitability of meat production.

scholarly journals Local and Systemic Up-regulation of TNFα, IL-1β and IL-6 in Mice Intratracheally Inoculated with Porphyromonas gingivalis

2008 ◽  
Vol 77 (3) ◽  
pp. 377-385 ◽  
Author(s):  
Z. Pavlica ◽  
A. Nemec ◽  
A. Nemec-Svete ◽  
D. Eržen ◽  
D. A. Crossley ◽  
...  
Keyword(s):  
Immune Response ◽  
Immune Responses ◽  
Porphyromonas Gingivalis ◽  
Total Protein ◽  
Protein Concentration ◽  
Serum Levels ◽  
Treated Group ◽  
Control Group ◽  
Total Protein Concentration ◽  
Sterile Phosphate Buffer

The objective of the study was to find whether a single intratracheal inoculation with live Porphyromonas gingivalis ATCC 33277 influences local and systemic inflammatory and immune responses in mice.Twelve-week-old BALB/c mice were intratracheally inoculated with 2.9 × 109 CFU P. gingivalis ATCC 33277 diluted in 40 μl sterile phosphate buffer (treated group) or with sterile PBS (control group). The animals were sacrificed 2, 6, 24, 72 and 168 h after inoculation. TNFα, IL-1β, IL-6 and total protein concentrations were measured in the serum, lungs and kidneys. Six hours after P. gingivalis inoculation, TNFα concentration was significantly increased in serum (p = 0.02) and kidneys (p = 0.04), but in the lungs TNFα production was enhanced already 2 h (p < 0.0001) after inoculation, reaching the peak after 6 h (p < 0.0001). The IL-1β concentration was also significantly increased in serum after 2 h (p = 0.006), remaining significantly elevated up to 3 days (p ≤ 0.0001) after inoculation. In lungs IL-1β levels were significantly increased 6 and 24 h (p < 0.0001) and in kidneys 24 h (p < 0.0001) and 168 h (p = 0.01) after inoculation. The IL-6 concentration was significantly increased in serum after 72 and 168 h (p < 0.0001). However, IL-6 was significantly increased in lungs after 6 h (p < 0.0001), remaining elevated until 72 h and in kidneys 2 and 6 h (p < 0.0001) after inoculation. Significantly increased total protein concentration was detected in kidneys 6 and 24 h (p < 0.0001) after inoculation. These results suggest that a single intratracheal inoculation with P. gingivalis stimulates the local and systemic inflammatory and immune response, as shown by increased tissue and serum levels of proinflammatory cytokines.

scholarly journals The Effect of a Silage Inoculant on Silage Quality, Aerobic Stability, and Meat Production on Farm Scale

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Y. Acosta Aragón ◽  
J. Jatkauskas ◽  
V. Vrotniakiene
Keyword(s):  
Lactic Acid ◽  
Lactobacillus Brevis ◽  
Metabolizable Energy ◽  
Water Soluble ◽  
Energy Concentration ◽  
Control Treatment ◽  
Meat Production ◽  
Soluble Carbohydrate ◽  
Feed Conversion ◽  
Aerobic Stability

The effect of inoculation on nutrient content, fermentation, aerobic stability, and beef cattle performance for whole-plant corn silage treated with a commercial product (blend of homo- and heterofermentative lactic acid bacteria, BSM, blend of Enterococcus faecium, Lactobacillus plantarum, and Lactobacillus brevis, DSM numbers 3530, 19457, and 23231, resp.), was compared to a control treatment with no silage additives (CT). The material had a DM of 323 g/kg, crude protein, and water-soluble carbohydrate concentrations of 87.9 and 110.5 g/kg DM, respectively. BSM increased the fermentation rate with a significantly deeper pH (P<0.01), a significant increase in the total organic acids concentration (P<0.05), more lactic acid (P<0.01), and numerically more acetic acid compared to CT. BSM significantly decreased the concentrations of butyric acid (P<0.01), ethanol, and ammonia-N compared to the CT. BSM-treated silage decreased DM by 3.0 % (P<0.01) and had a higher digestible energy and a higher metabolizable energy concentration by 2.3 (P<0.01) and 1.00 % (P<0.05), respectively, compared to untreated silage. Aerobic stability improved by more than 2 days in BSM silage. The DM intake of silage treated with BSM increased by 6.14 %, and improved weight gain and the feed conversion by 8.0 (P<0.01) and 3.4%.

scholarly journals Safety and effectiveness of high-dose vitamin C in patients with COVID-19: a randomized open-label clinical trial

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Saeidreza JamaliMoghadamSiahkali ◽  
Besharat Zarezade ◽  
Sogol Koolaji ◽  
SeyedAhmad SeyedAlinaghi ◽  
Abolfazl Zendehdel ◽  
...  
Keyword(s):  
Vitamin C ◽  
Controlled Trial ◽  
Water Soluble ◽  
Control Treatment ◽  
Control Group ◽  
Case Group ◽  
High Dose ◽  
Open Label ◽  
Mean Body Temperature ◽  
Significant Difference

Abstract Background Vitamin C is an essential water-soluble nutrient that functions as a key antioxidant and has been proven to be effective for boosting immunity. In this study, we aimed to assess the efficacy of adding high-dose intravenous vitamin C (HDIVC) to the regimens for patients with severe COVID-19 disease. Methods An open-label, randomized, and controlled trial was conducted on patients with severe COVID-19 infection. The case and control treatment groups each consisted of 30 patients. The control group received lopinavir/ritonavir and hydroxychloroquine and the case group received HDIVC (6 g daily) added to the same regimen. Results There were no statistically significant differences between two groups with respect to age and gender, laboratory results, and underlying diseases. The mean body temperature was significantly lower in the case group on the 3rd day of hospitalization (p = 0.001). Peripheral capillary oxygen saturations (SpO2) measured at the 3rd day of hospitalization was also higher in the case group receiving HDIVC (p = 0.014). The median length of hospitalization in the case group was significantly longer than the control group (8.5 days vs. 6.5 days) (p = 0.028). There was no significant difference in SpO2 levels at discharge time, the length of intensive care unit (ICU) stay, and mortality between the two groups. Conclusions We did not find significantly better outcomes in the group who were treated with HDIVC in addition to the main treatment regimen at discharge. Trial registration irct.ir (IRCT20200411047025N1), April 14, 2020

scholarly journals Effect of add exogenous fibrolytic enzymes to the ration in some characteristics of blood biochemicals of Awassi lactating ewes

2018 ◽  
Vol 11 (1) ◽  
pp. 70-83
Author(s):  
G Al-Rubaie ◽  
H Ajeel ◽  
S Khalaf
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
Enzyme Concentration ◽  
High Density ◽  
Control Treatment ◽  
Control Group ◽  
Treatment Control ◽  
Fibrolytic Enzymes ◽  
Pregnant Sheep ◽  
Very High

The experiment was conducted in the field of animal production of the research ruminants- Office of Research- Ministry of Agriculture in the region of Akrokov 25 km northwest of Baghdad for the period from 16/3/2016 to 4/6/2016, and the objective of the experiment was the effect of addition of different levels of fibrolytic enzymes. The concentrate diet on some characteristics biochemical blood lactating Ewes Awassi, In the first experiment, 26 pregnant sheep were used In the late stage and before birth and at the age of 3-5 years, With a weight of 67 kg, The first experiment lasted 42 days preceded by 10 days introductory period The ewes were divided into four groups, each with 6 ewes, of which 15 were born, Treatment control 3 ewes, first treatment 5 ewes, second treatment 4 ewes, third treatment 3 ewes, The trial period was divided into three successive periods from birth every 14 days, The first period of 0-14 days and the second period of 15-28 days and the third period of 29 to 42 days of the milk cycle began, Control group without enzyme and treatment of the first, second and third enzyme concentration 1,3,5 kg/t respectively. The preliminary period is 10 days ahead, The results showed that: The addition of fibrolytic enzymes to the cencenterate diet of the fodder resulted in Significant increase (P<0.01) was observed at the general rate of concentration of urea, The concentration of urea was significantly increased only in T3, while cholesterol was significantly higher in all treatments compared to the control treatment. And significantly increased triglycerides in T2 compared to all other treatments. Very high-density lipoprotein was increased in T1 treatment with control treatment C, as well as significant increase (P≤0.05) high-density lipoprotein in treatment T1 compared to treatment control C and the recording of high-density lipoprotein (HDL) significantly higher in T2 compared to all treatments triglyceride, and very high-density lipoprotein, (P<0.05) for high density lipoprotein (LDL) and low-density lipoprotein. LDL was significantly increased in T3 compared to T1. The serum AST (T3) was significantly increased in T3 compared to T2, T1 in the serum of lactating ewes.

scholarly journals Вплив нанопрепаратів кластерних сполук ренію на активність ферментів печінки в моделі пухлинного росту

2010 ◽  
Vol 1 (2) ◽  
pp. 76-80
Author(s):  
J. V. Suponko ◽  
N. I. Shtemenko
Keyword(s):  
Aqueous Solution ◽  
Enzymatic Activity ◽  
Water Soluble ◽  
Hepatoprotective Effect ◽  
Cluster Compounds ◽  
Control Group ◽  
Simultaneous Injection ◽  
Anticancer Properties ◽  
Rhenium Cluster ◽  
Guerin’S Carcinoma

Enzymes’ level in rat’s hepatocytes under Guerin's carcinoma T8 development as well as after injection of rhenium compounds and cis-platin has been studied. It has been determined that the decrease of enzymatic activity to the level of the animals of control group was observed at the simultaneous injection of cis-platin and cluster rhenium compounds in nanoliposomal and water-soluble forms. That confirms possible hepatoprotective properties of the rhenium compounds. It has been shown that hepatoprotective properties of rhenium cluster compounds mostly don’t depend on the form of their injection and are detected regardless of anticancer properties. Rhenium-platinum system with β-alanine ligand in aqueous solution, has been found. Its injection is accompanied by the hepatoprotective effect.

Effects of three methods of oral selenium-enriched yeast supplementation on blood components and growth in Holstein dairy calves

2019 ◽  
Vol 59 (2) ◽  
pp. 260 ◽  
Author(s):  
M. Mohrekesh ◽  
A. D. Foroozandeh Shahraki ◽  
G. R. Ghalamkari ◽  
H. Guyot
Keyword(s):  
Total Protein ◽  
Protein Concentration ◽  
Dairy Calves ◽  
Control Group ◽  
Blood Components ◽  
Total Protein Concentration ◽  
Maternal Supplementation ◽  
Blood Characteristics

The objective of this study was to investigate the effect of three methods of oral selenium-enriched yeast (Se-yeast) supplementation on the blood characteristics and growth of Holstein dairy calves. The three methods were: (1) maternal (dams supplemented with 0.3 mg Se per kg of dietary DM during 3 weeks pre-calving), (2) post-calving (calf starter enriched with 0.3 mg Se per kg of DM), and (3) maternal and post-calving Se-yeast supplementation. These three methods were compared with a control group (no supplementation). Maternal supplementation with Se-yeast successfully increased Se concentration in the colostrum and the serum of calves 24 h after calving (P &lt; 0.05). At day 56, the Se concentration in the blood of calves supplemented with Se-yeast pre- (maternal) or post-calving (via starter) was greater than the control group (P &lt; 0.05), but maternal plus post-calving supplementation was not more effective than either maternal or post-calving supplementation. Globulin and total protein concentration in the blood of calves at day 0 increased and albumins:globulins decreased with maternal supplementation (P &lt; 0.05), but these variables were similar for all treatments at day 56. Immunoglobulins in the blood of calves and colostrum were not affected by maternal Se-yeast supplementation. Maternal supplementation increased the concentration of urea in the blood of calves at 0 days (P &lt; 0.05), but not at 56 days. Calf birthweight was increased with maternal supplementation of Se-yeast (P &lt; 0.01), but growth to day 56 was not affected by the methods of Se supplementation. Maternal supplementation with Se-yeast may improve growth and health characteristics of calves at calving time.

Utilization of Tofu Dregs Flour in Making Snack Bars for People with Diabetes Mellitus

2020 ◽  
Vol 7 (1) ◽  
pp. 27
Author(s):  
Ni Putu Diah Cahyani Subamia ◽  
Komang Ayu Nocianitri ◽  
I Dewa Gede Mayun Permana
Keyword(s):  
Diabetes Mellitus ◽  
Blood Sugar ◽  
Wheat Flour ◽  
Sugar Content ◽  
Type Ii Diabetes Mellitus ◽  
Positive Control ◽  
Water Soluble ◽  
Control Group ◽  
Unhealthy Lifestyle ◽  
Control Group Design

Type II diabetes mellitus due to an unhealthy lifestyle, one of which is the lack of fiber in daily food consumption. One food that has a high fiber content is tofu dregs. The purpose of this study was to determine substitution of wheat flour with tofu dregs flour to produce a snack bar with the best characteristics, and determine the effect of consumption of snack bar from tofu dregs on blood sugar content in rats. The research was conducted two steps. Step I: Formulation of snack bar using a completely randomized design with tofu dregs flour concentration of 0 %, 10 %, 20 %, 30 %, 40 %, and 50 %. The variables of this study were the content of water, ash, protein, fat, carbohydrates, sensory tests, and effectiveness tests. Step II: the best characteristic snack bar in the step I was used experimental rats. This step used true experimental design with pre-post test control group design. The variables of study were blood glucose levels before treatment and after treatment. The treatment group consisted of normal, negative, positive control, and snack bar. The results of the first step of the research showed that substitution of wheat flour with 40 % tofu dregs produced the best characteristic snack bar with 17.19 % water content, 1.33 % ash content, 11.03 % protein, 20.53 % fat, 49.92 % carbohydrate, light brown color, unpleasant aroma, distinctive soy taste, crumb texture, 0.63 % water soluble food fiber, 1.57 % water insoluble fiber, and total food fiber 2.36 %. The results of the second step of the study showed that the provision of substitution of wheat flour with tofu dregs flour 40 % could reduce blood sugar levels in diabetic mellitus rats until normal, start 290 mg/dl to 108.5 mg/dl. Tofu dregs flour can be used for snack bar formulations for people with diabetes mellitus.

The use of acidifying agents Aquasafe and Veleguard when rearing of broiler chickens

2020 ◽  
pp. 16-27
Author(s):  
L. Gamko ◽  
T. Tarinskaya
Keyword(s):  
Drinking Water ◽  
Organic Acids ◽  
Broiler Chickens ◽  
Positive Impact ◽  
The Body ◽  
Metabolic Energy ◽  
Control Group ◽  
Meat Production ◽  
Feed Conversion ◽  
Broiler Meat

It is known that necessary to replace the components of organic acids, which are part of acidifiers when drinking water to poultry in order to prevent the adaptation of microbes in the gastrointestinal tract. In the poultry industry organic acids are widely used, which are used as acidifiers to preserve the properties of water consumed. The purpose of this work was to evaluate the efficiency of broiler meat production when using acidifying agents of drinking water Aquasafe and Veleguard. The experimental part of the work has been performed in JSC “Kurinoe Tsarstvo-Bryansk” broiler area “Roshcha” in the Pochepsky district. The object of research was the livestock of broiler chickens cross Cobb 500 at floor housing. The effect of water acidifiers on meat productivity has been studied. Groups of chickens have been formed on the principle of pairs-analogues. Broiler chickens of experimental groups have been separated from the main livestock by a grid in the corner of the room for 100 heads in each group. It has been found by a result of research to be optimal dose usage of acidifying agents water Aquasafe and Veleguard to drink to broiler chickens. The positive effect of these acidifiers on the digestion of crude protein, crude fat, crude fiber, contributing to the effective use of nitrogen, which led to an increase in the intensity of growth, young animals’ livability and improved feed conversion. Slaughter yield in the control group was 55,1 %, and in the experimental group 57,2 and 58,4 %, which was by 2,1 and 3,3 % higher with the same level of metabolic energy and nutrients. In chickens that consumed acidifi ers more intensively used nutrients feed for deposition in the body of the components of the carcass, which affected the production. A positive impact of acidifying agents Aquasafe and Veleguard on meat quality in broiler chickens has been found.

Mechanism Involved in Fortification by Berberine in CDDP-Induced Nephrotoxicity

2020 ◽  
Vol 13 (4) ◽  
pp. 342-352 ◽  
Author(s):  
Vipin K. Verma ◽  
Salma Malik ◽  
Ekta Mutneja ◽  
Anil K. Sahu ◽  
Kumari Rupashi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Renal Tissue ◽  
Isoquinoline Alkaloid ◽  
Experimental Models ◽  
Beclin 1 ◽  
Control Treatment ◽  
Control Group ◽  
Treatment Groups ◽  
Single Intraperitoneal Injection ◽  
Male Wistar Rats

Background: The activation of Nrf2/HO-1 pathway has been shown to protect against cisplatin- induced nephrotoxicity by reducing oxidative stress. Berberine (Ber), an isoquinoline alkaloid, has demonstrated antioxidant, anti-inflammatory and anti-apoptotic activities in various experimental models. Aim: To check the effect of Ber on cisplatin-induced nephrotoxicity and to explore the involved mechanism. Methods: Adult male Wistar rats were divided into 6 groups: Normal, cisplatin-control, treatment groups and per se group. Normal saline and Ber (20, 40 and 80 mg/kg; p.o.) was administered to rats for 10 days. A single intraperitoneal injection of cisplatin (8 mg/kg) was injected on 7th day to induced nephrotoxicity. On 10th day, rats were sacrificed, the kidney was removed and stored for the estimation of various parameters. Results: As compared to cisplatin-control group, Ber pretreatment improved renal function system and preserved renal architecture. It also diminished oxidative stress by upregulating the expression of Nrf2/HO-1 proteins. In addition, Ber attenuated the cisplatin mediated inflammation and apoptosis. Furthermore, it also reduced the phosphorylation of p38/JNK and PARP/Beclin-1 expression in the kidney. Conclusion: Ber attenuated renal injury by activating Nrf2/HO-1 and inhibiting JNK/p38MAPKs/ PARP/Beclin-1 expression which prevented oxidative stress, inflammation, apoptosis and autophagy in renal tissue.

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