Training-induced adaptation in purine metabolism in high-level sprinters vs. triathletes

The aim of this study was to assess the effect of training loads on metabolic response of purine derivatives in highly trained sprinters (10 men, age range 20–29 yr) in a 1-yr cycle, compared with endurance-training mode in triathletes (10 men, age range 21–28 yr). A four-time measurement of respiratory parameters, plasma hypoxanthine (Hx) concentration, and erythrocyte hypoxanthine-guanine phosphoribosyl transferase (HGPRT) activity was administered in four characteristic training phases (general, specific, competition, and transition). A considerably lower postexercise plasma concentration of Hx in sprinters (8.1–18.0 μmol/l) than in triathletes (14.1–24.9 μmol/l) was demonstrated in all training phases. In both groups, a significant decrease in plasma Hx concentration in the competition phase and a considerable increase in the transition phase were observed. It was found that the resting erythrocyte HGPRT activity increased in the competition period and declined in the transition phase. Sprinters showed higher HGPRT activity (58.5–71.8 nmol IMP·mg Hb−1·h−1) than triathletes (55.8–66.6 nmol IMP·mg Hb−1·h−1) in all examinations. The results suggest a more effective use of anaerobic metabolic energy sources induced by sprint training characterized by higher amount of exercise in the anaerobic lactacid and the nonlactacid zone. The changes in plasma Hx concentration and erythrocyte HGPRT activity might serve as sensitive metabolic indicators in the training control, especially in sprint-trained athletes. These parameters may provide information about the energetic status of the muscles in highly trained athletes in which no significant adaptation changes are detected by means of commonly acknowledged biochemical and physiological parameters.

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Heart Rate Recovery Changes during Competition Period in High-Level Basketball Players

Baltic Journal of Sport and Health Sciences ◽

10.33607/bjshs.v1i80.334 ◽

2018 ◽

Vol 1 (80) ◽

Author(s):

Audrius Gocentas ◽

Anatoli Landõr ◽

Aleksandras Kriščiūnas

Keyword(s):

Heart Rate ◽

Heart Rate Recovery ◽

Team Sports ◽

Basketball Players ◽

Coeffi Cients ◽

Competition Period ◽

Monitoring Training ◽

Intense Training ◽

High Level

Research background and hypothesis. Replete schedule of competitions and intense training are features of contemporary team sports. Athletes, especially the most involved ones, may not have enough time to recover. As a consequence, aggregated fatigue can manifest in some undesirable form and affect athlete’s performance and health.Research aim. The aim of this study was to evaluate the changes in heart rate recovery (HRR) and investigate possible relations with sport-speciﬁ c measures of efﬁ cacy in professional basketball players during competition season.Research methods. Eight male high-level basketball players (mean ± SD, body mass, 97.3 ± 11.33 kg; height 2.02 ± 0.067 m, and age 23 ± 3.12 years) were investigated. The same basketball speciﬁ c exercise was replicated several times from September till April during the practice sessions in order to assess the personal trends of HRR. Heart rate monitoring was performed using POLAR TEAM SYSTEM. Investigated athletes were ranked retrospectively according to the total amount of minutes played and the coefﬁ cients of efﬁ cacy. Research results. There were signiﬁ cant differences in the trends of HRR between the investigated players. The most effective players showed decreasing trends of HRR in all cases of ranking.Discussion and conclusions. Research ﬁ ndings have shown that the quality of heart rate recovery differs between basketball players of the same team and could be associated with sport-speciﬁ c efﬁ cacy and competition playing time.Keywords: adaptation, autonomic control, monitoring training.

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The Potential of Building Tourist Cities by Using Existing Resources in Uzbekistan with an Innovative Approach

Indonesian Journal of Law and Economics Review ◽

10.21070/ijler.2020.v7.480 ◽

2020 ◽

Vol 6 ◽

Author(s):

Madina M. Khashimova ◽

Shakhzod F. Turakulov

Keyword(s):

Highly Qualified ◽

Natural Conditions ◽

Foreign Countries ◽

Economic Infrastructure ◽

The Republic ◽

High Level ◽

Effective Use ◽

Steep Slopes ◽

Training Area

This article reflects the construction of tourist cities using the resources available on the territory of Uzbekistan. The benefits of utilisation for the development of tourism infrastructure from geological cities that are not exploited, included in the available resources, have been analyzed. The high level of efficiency in the use of geological cities is based on the availability of economic infrastructure, which is recognized as the application of this infrastructure in the construction of tourist cities is low in costs. The article shows the specific natural anchors of three ecotouristic objects, the srategic plans for effective use of these anchors. Proposals on the expediency of the establishment of camps, bags, summer recreation zones are included in these facilities. The abundance of excursion facilities and attractions in the objects of ecotourism expressed their views on the possibility of opening remarkable travel destinations. And the steep slopes of the mountain are shown to be a special training area for training highly qualified climbers. Reflecting the peculiarities of the nature of the objects of the ecosystem, the role of these settlements with unique natural conditions in the development of tourism is established. The potential for the construction of such ecotouristic cities in the Republic of Uzbekistan is high, and the growth in the efficiency of the use of such potentials is reported to increase the number of tourists coming from foreign countries to Uzbekistan.

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High-level Exposure of Uric Acid in Asymptomatic Hyperuricemia Could Be An Isolated Risk Factors of Cardio-Cerebrovascular Diseases: A Prospective Cohort Study

10.21203/rs.3.rs-230583/v1 ◽

2021 ◽

Author(s):

Zhiyuan Cheng ◽

Tongzhang Zheng ◽

Desheng Zhang ◽

Jingli Yang ◽

Xiaobin Hu ◽

...

Keyword(s):

Cardiovascular Disease ◽

Uric Acid ◽

Cox Regression ◽

Cerebrovascular Diseases ◽

Healthy Population ◽

Incidence Risk ◽

High Level ◽

Age Range ◽

Fourth Quartile

Abstract Background: Whether the asymptomatic hyperuricemia (AH) raises the risk of cardiovascular disease with or without hyperuricemia-related comorbidities still remains contentious. Our study was aimed to quantitatively access the incidence risk of coronary heart disease (CHD) and stroke associated with AH.Methods: Multivariate-adjusted Cox regression models were applied to evaluate the risk of cardiovascular disease (CVD). Serum uric acid beyond normouricemia was quarterly stratified based on the distribution of healthy population without CVD onset.Results: 1,062 CVD first attack cases were collected among the 48,001 cohort participants (age range: 18-92, mean age: 47.2±13.9 years-old) with a mean follow-up duration of 5.78±0.83 years. 14,464 baseline population with comorbidities were excluded to further study the association between AH and CVD incidence. The AH showed overall non-association with CVD incident. However, significantly increased adjusted hazard ratio (HR) of CVD with 95% confidence interval (CI) were observed when the fourth quartile compared with normouricemia stratum in the total cohort population (CHD: 1.70, 1.34-2.16; stroke: 1.55, 1.13-2.13), male (CHD: 1.94, 1.47-2.56), female (CHD: 1.71, 1.03-2.35; stroke: 2.02, 1.14-3.58) and aged over 50 years-old population. Meanwhile, the age-standardized incidence rate of CVD in the fourth quartile was 2 to 3 time higher than the normouricemia population. Consistent results were also observed in the AH population in absence of comorbidities (CHD: 2.40, 1.39-4.14; stroke: 1.85, 1.12-3.59).Conclusion: Asymptomatic hyperuricemia patients exposed to higher level of uric acid (male>487 mmol/L, female>422 mmol/L) could significantly increase the incidence risk of CHD and stroke, with or without hyperuricemia-related comorbidities.

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Seismic anisotropy

Geophysics ◽

10.1190/1.1444917 ◽

2001 ◽

Vol 66 (1) ◽

pp. 40-41 ◽

Cited By ~ 20

Author(s):

Leon Thomsen

Keyword(s):

Future Development ◽

Seismic Data ◽

Seismic Anisotropy ◽

Practical Interest ◽

Exploration And Exploitation ◽

Principal Reason ◽

The Past ◽

High Level ◽

Effective Use

The topic of seismic anisotropy in exploration and exploitation has seen a great deal of progress in the past decade‐and‐a‐half. The principal reason for this is the increased (and increasing) quality of seismic data, of the processing done to it, and of the interpretation expected from it. No longer an academic subject of little practical interest, it is now often viewed as one of the crucial factors which, if not taken into account, severely hampers our effective use of the data. The following brief overview is not intended to be exhaustive, since any such attempt would surely be incomplete. However, it does provide a high‐level survey of the advances seen (at the end of this period) to be important by one who was closely involved, and it directly extrapolates this history to predict the future development of the topic.

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Gynecological problems and reproductive health awareness amongst late adolescent girls pursuing professional courses: a questionnaire based survey

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20193056 ◽

2019 ◽

Vol 8 (7) ◽

pp. 2861

Author(s):

Rambabu Chennuru ◽

Jarina Begum

Keyword(s):

Undergraduate Students ◽

Late Adolescent ◽

Medical College ◽

High Prevalence ◽

Dark Pigmentation ◽

Menstrual History ◽

High Level ◽

Age Range ◽

Ovarian Syndrome ◽

Structured Questionnaire

Background: Dysmenorrhoeais a debilitating menstrual problem and may be related to body mass index (BMI). This study was done to explore the various gynecological problems in girls in their late adolescence that is pursuing professional courses in medicine, dental and nursing.Methods: This was a prospective, questionnaire based study conducted between January and February 2019 in a medical college in Visakhapatnam, India. The survey included female undergraduate students of the Medical, Dental and Nursing colleges to find out their menstrual history and reproductive awareness with the help of a self-structured questionnaire. Participants were categorized based on BMI. Data was reported as number and percentage.Results: Of the 190 participants, 154 participants (age range; 16-19 years) were included in the study. Fifty percent of the total participants reported to have dysmenorrhoea, of which 21% reported severe dysmenorrhoea. A very high % of participants in the obese category (77.8%) reported severe dysmenorrhoea, followed by 27.3% in the underweight category. A U-shaped relationship between percentage of participants with severe dysmenorrhoea and increasing BMI was observed. A fair percentage of obese participants reported for infrequent periods beyond 35-45 days and androgenic features like excess hair, acne and dark pigmentation around neck, suggestive of polycystic ovarian syndrome (PCOS). The participants possessed a high level of awareness and reported in the range of 87.1 to 96.8% related to reproductive health.Conclusions: Despite high level of awareness among the participants we observed a considerably high prevalence of dysmenorrhoea which was even more prevalent, in the obese category.

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Effect of weight-control practices of high-level female judokas over competition period on body composition and factors of performance

Science & Sports ◽

10.1016/j.scispo.2018.12.012 ◽

2019 ◽

Vol 34 (5) ◽

pp. 305-312

Author(s):

M. Gallot ◽

H. Zorgati ◽

F. Prieur ◽

N. Rebot-Vibarel ◽

K. Collomp ◽

...

Keyword(s):

Body Composition ◽

Weight Control ◽

Competition Period ◽

High Level

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Digital Transformation

Managerial Issues in Digital Transformation of Global Modern Corporations - Advances in Logistics, Operations, and Management Science ◽

10.4018/978-1-7998-2402-2.ch002 ◽

2021 ◽

pp. 16-31

Author(s):

Chandra Sekhar Patro ◽

K. Madhu Kishore Raghunath

Keyword(s):

Business Models ◽

Digital Technologies ◽

Digital Transformation ◽

Product Reviews ◽

Business Units ◽

New Business ◽

Modern Business ◽

Business Enterprises ◽

High Level ◽

Effective Use

Digital transformation and innovative business models are enabling a high level of competition among business enterprises. The worldwide adoption of the internet and an increasing number of associated technologies have strengthened the digital transformation. Digital technologies allow the customers to co-create value by designing and customizing products, perform last-mile distribution activities, and help other customers by sharing product reviews. Digital transformation is an enterprise-wide phenomenon that leads to the development of new business. This is intrinsically linked to strategic changes in the business model as a result of the implementation of digital technologies models, which may be new to the focal business units or industry. The chapter articulates the influence of digital transformation on the performance of business enterprises in the competitive environment. It analyzes the barriers to the effective use of digital technologies and also the digital transference initiatives of modern business enterprises.

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Acute and Short-Term Response to Different Loading Conditions During Resisted Sprint Training

International Journal of Sports Physiology and Performance ◽

10.1123/ijspp.2019-0723 ◽

2020 ◽

Vol 15 (7) ◽

pp. 997-1004

Author(s):

Beatriz Bachero-Mena ◽

Miguel Sánchez-Moreno ◽

Fernando Pareja-Blanco ◽

Borja Sañudo

Keyword(s):

Creatine Kinase ◽

Blood Lactate ◽

Physical Performance ◽

Metabolic Response ◽

Training Session ◽

Sprint Performance ◽

Loading Conditions ◽

Sprint Training ◽

Countermovement Jump ◽

Short Term

Purpose: To analyze the acute and short-term physical and metabolic responses to resisted sprint training with 5 different loading conditions (0%, 20%, 40%, 60%, and 80% body mass). Methods: Fifteen male participants performed 8 × 20-m sprints with 2-minute rests between sprints with 5 different loading conditions. Subjects performed a battery of tests (creatine kinase and lactate concentrations, countermovement jump, 20-m sprint, and isokinetic knee extension and flexion contractions) at 3 different time points (preexercise [PRE], postexercise [POST], and 24-h postexercise [POST24H]). Results: Results revealed significant increases in blood lactate for all loading conditions; however, as sled loadings increased, higher blood lactate concentrations and increments in sprint times during the training session were observed. Significant increases in creatine kinase concentration were observed from PRE to POST24H for all loading conditions. Concerning physical performance, significant decreases in countermovement-jump height from PRE to POST were found for all loading conditions. In addition, significant decreases in 20-m sprint performance from PRE to POST were observed for 0% (P = .05) and 80% (P = .02). No significant differences with PRE were observed for the physical-performance variables at POST24H, except for 20% load, which induced a significant decrease in mean power during knee flexion (P = .03). Conclusions: These results suggest that the higher the load used during resisted sprint training, the higher the physical-performance impairments and metabolic response produced, although all loading conditions led to a complete recovery of sprint performance at POST24H.

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Effect of Religiosity and Moral Identity Internalization on Prosocial Behaviour

Journal of Human Values ◽

10.1177/0971685820901402 ◽

2020 ◽

Vol 26 (2) ◽

pp. 186-198

Author(s):

Sukhamjit Kaur

Keyword(s):

Moral Reasoning ◽

Emerging Adults ◽

Perspective Taking ◽

Personality Assessment ◽

Moral Identity ◽

Empathic Concern ◽

Prosocial Behaviour ◽

Socially Responsible ◽

High Level ◽

Age Range

The main aim of the present research was to study the religiosity and moral identity internalization as effective variables of prosocial behaviour. Sample consisted of 400 emerging adults (females) in the age range of 18–24. All participants completed questionnaire measures, namely religiosity scale (Bhushan, 1970), moral identity inventory (Aquino & Reed, 2002, Journal of Personality and Social Psychology, 83, 1423–1440) and prosocial personality battery (Penner, Fritzsche, Craiger & Friefeld, 1995, Advances in Personality Assessment (vol. 10, pp. 147–184). Hillsdale, NJ: Lea). The data were subjected to 2 × 2 analysis of variance. The results of ANOVA clearly revealed that highly religious people are more responsible socially, exhibit higher empathic concern, are more able to take others perspective, have higher prosocial moral reasoning capabilities, are more helpful, altruistic and demonstrate a high level of other oriented empathy. High moral identity internalization leads to socially responsible behaviour, along with higher empathic concern and perspective-taking abilities. Individuals with high level of moral identity were found capable to use prosocial moral reasoning, and they also exhibited higher levels of other oriented empathy. Religiosity and moral identity internalization interacted with each other to produce a combined effect on mutual concern moral reasoning.

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