Impact of age and gender in patients with thin melanoma

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 8056-8056 ◽  
Author(s):  
C. K. Chang ◽  
S. K. Liu ◽  
J. S. Choi ◽  
R. C. Liu ◽  
P. F. Fuchshuber
Keyword(s):  
Cox Regression ◽  
Univariate Analysis ◽  
Age Groups ◽  
Rank Test ◽  
Superficial Spreading ◽  
Chi Square ◽  
Age And Gender ◽  
Thin Melanoma ◽  
Male Ratio ◽  
And Gender

8056 Background: The incidence of thin melanoma (≤ 1mm) continues to increase. The purpose of this study was to characterize the incidence and prognosis of thin melanoma among the various age groups. We analyzed the records of 15,267 patients diagnosed with melanoma of these we were able to identify 5573 patients with thin melanoma (≤ 1mm). Methods: A retrospective review was undertaken to identify patients with thin melanoma (<1mm) treated at all the Northern California Kaiser Permanente facilities. All patients received their treatment between January 1998 and December 2004. Univariate and multivariate analyses of predictive factors were evaluated with the log-rank test and Cox regression. In addition chi-square test of relevant clinicopathologic factors determined which factors were predictive of overall survival (OS). Results: Mean age was 55 years (range 8–101). Mean follow-up was 74 months (range 3–209) and 54% were male. Primaries were on the trunk (34%), lower extremities (19%), upper extremities (26%), or head/neck (20%). Mean thickness was 0.4 ± 0.25 mm. The most common histology was superficial spreading (88%). The overall 5 and 10 year survival were 89 and 79, respectively. By univariate analysis age, sex, location and histology were predictive of OS however by multivariate analysis only age and sex were predictive of OS. The female/male ratio was 2 in patients diagnosed before the 3rd decade, and this ratio approached 1 in the mid-5th decade. However, the female/male ratio was 0.5 among patients diagnosed with melanoma in their 8th decade. Conclusions: Females are more susceptible than men to the risk of melanoma at a younger age however this susceptibility changes with increasing age. Our results demonstrate that the incidence of melanoma may be influenced by age and gender. No significant financial relationships to disclose.

The Influence of Age and Gender on Mandibular Indices among the Libyan Population

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Negative Correlation ◽  
Bone Mineralization ◽  
Age Groups ◽  
T Test ◽  
Chi Square ◽  
Age And Gender ◽  
Significant Difference ◽  
Chi Square Test ◽  
And Gender ◽  
Libyan Population

Radiographic Mandibular Indices serve as easy and relatively cheap tools for evaluating bone mineralization. Objectives: To examine the effect of age and gender on three mandibular indices: the panoramic mandibular index (PMI), the mandibular ratio (MR) and the mandibular cortical index (MCI), among Libyan population. Methods: The three indices were measured on 317 digital (OPGs) of adult humans (155 males, 162 females). The sample was divided into six age groups (from 18-25 years through 56-65 years). The measurements were analyzed for interactions with age and sex, using SPSS (Statistical Package for Social Studies) software version no. 22. The tests employed were two way ANOVA, the unpaired T-test and chi-square test. Results: The mean PMI fluctuated between 0.37 s.d. 0.012 and 0.38 s.d. 0.012. among the sixth age groups. One-way ANOVA statistical test revealed no significant of age on PMI. On the other hand gender variation has effect on PMI, since independent sample t-test disclosed that the difference between the male and female PMI means statistically significant. ANOVA test showed that the means of MR among age groups showed a negative correlation i.e. MR mean declined from 3.01 in 18-25 age groups to 2.7 in 55-65 age groups. In contrary, the gender showed no effect on MR according two sample t-test at p> 0.05. In regards with MCI, statistical analysis showed that it affected by age that is C1 was decreasing by age while C2 and C3 were increased by age. Using chi square test the result indicated that there is a significant difference among the different age group and the two genders in MCI readings. Conclusion: PMI was influenced significantly by age but minimally by the gender. MR is not affected by gender but has a negative correlation with age. MCI is affected by both age and gender

scholarly journals The Description of Diphtheria Immunization History to Diphtheria Patients in Surabaya at 2017

2018 ◽  
Vol 6 (2) ◽  
pp. 103
Author(s):  
Ayu Fitriansyah
Keyword(s):  
Hepatitis B ◽  
Research Design ◽  
Univariate Analysis ◽  
Age Groups ◽  
Health Development ◽  
Age And Gender ◽  
Frequency Table ◽  
History Of ◽  
Case Rate ◽  
And Gender

Background: Diphteria can be prevented by immunization of DPT-HB-Hib (Diphteria, Hepatitis B, dan Haemophillus Influenze B) to infants and DPT-HB-Hib Booster, DT (Diphteria Tetanus) and Td (Tetanus Diphteria) afterwards. In 2017, diphteria case rate in Surabaya was high, 29 cases, due to the lack of 7 dosages of diphteria immunization. Purpose: This study aimed to depict the completion history of diphteria immunization based on the completness of immunization status which suits to age groups of diphteria patients in Surabaya in 2017. Methods: This study was quantitave descriptive with study cross research design. The objects of this study were diphteria patients in Surabaya in 2017 (29 individuals). Data was collected by quisionaire and immunization record from KIA/KMS books which belongs to Government effort to control Citizen Health Development. The variables of this study was diphteria patients characteristics (age and gender) and the history diphteria immunization. Data were analyzed using univariate analysis with frequency table.  Results: This study obtained that mostly the diphteria patients in Surabaya in 2017 suffered this disease in 18 until 84 months old (58.62%) and mostly happened to male (82.76%). All patients aged 18 months old received complete diphteria immunization (3.45%), but all patient aged more than ≥ 18 months old did not received complete diphteria immunization (96.55%). Mostly the patients did not receive re-immunization afterwards, i.e DPT-HB-Hib Booster, DT, and Td. Conclusion: The completion 7 dosages of diphteria immunization is important to diphteria cases, especially to diphteria re-immunization afterwards.

scholarly journals Dental Treatment Need Among First-Visit Patients Of Dental Outpatient Clinic At IIUM Kuantan For The Year 2016

2017 ◽  
Vol 16 (2) ◽  
Author(s):  
Azlini Ismail ◽  
Zurainie Abllah ◽  
Nur Aishah Muhammad Radhi ◽  
Syazalina Musa ◽  
Mohd Firdaus Akbar Abdul Halim
Keyword(s):  
Outpatient Clinic ◽  
Dental Treatment ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Age And Gender ◽  
Treatment Need ◽  
Human Ethics ◽  
And Gender

Introduction: This cross-sectional study aimed to determine association of age and gender with dental treatment need among first-visit patients at Dental Outpatient Clinic, IIUM Kuantan in 2016. Materials and Methods: Ethical approval (IREC 762) was obtained from IIUM Human Ethics Committee. List of first-visit patients who attended clinic from 1st January to 31st December 2016 was retrieved to assess patient's age and gender. Dental treatment need was determined according to the normative need which was professionally defined by dental-officer-in-charge. All first-visit patients were included, except those attended Orthodontic department or with old Malaysian identification card or foreign passport. Included patients were classified into six age groups (≤14, 15-19, 20-34, 35-44, 45-64 and ≥ 65). Pearson's chi square test was used for statistical analysis using SPSS Version 20 software. Results:  From a total number of 2,713 patients (age range of 2 to 87), 1,210 (44.6%) were males and 1,503 (55.4%) were females. Age (p<0.001) and gender (p<0.001) were significantly associated with dental treatment need. Paediatric patients (≤14) majorly received paedodontic care (97.5%). Young-age patients (15-19, 20-34 and 35-44) mostly required conservative care (39.5%, 31.2% & 30.6%, respectively) while elder-age patients (45-64 and ≥ 65) have major need for prosthodontics (30.0% & 40.2%, respectively). Females outnumbered males in all age groups, except for the age group of ≥ 65 whereby the situation was the opposite. Females also outnumbered males in all types of treatment need, except for periodontics which was predominated by males. Conclusion(s):  Age and gender have significant associations with treatment need for dental care.

Children’s Lives and Deaths in Merovingian Gaul

2020 ◽  
pp. 185-213
Author(s):  
Émilie Perez
Keyword(s):  
Social Identity ◽  
Age Groups ◽  
New Method ◽  
Recent Analysis ◽  
Age And Gender ◽  
The Past ◽  
And Gender ◽  
Grave Goods

The role of children in Merovingian society has long been downplayed, and the study of their graves and bones has long been neglected. However, during the past fifteen years, archaeologists have shown growing interest in the place of children in Merovingian society. Nonetheless, this research has not been without challenges linked to the nature of the biological and material remains. Recent analysis of 315 children’s graves from four Merovingian cemeteries in northern Gaul (sixth to seventh centuries) allows us to understand the modalities of burial ritual for children. A new method for classifying children into social age groups shows that the type, quality, quantity, and diversity of grave goods were directly correlated with the age of the deceased. They increased from the age of eight and particularly around the time of puberty. This study discusses the role of age and gender in the construction and expression of social identity during childhood in the Merovingian period.

Age and gender differences in socially aversive (“dark”) personality traits

2021 ◽  
pp. 089020702098843
Author(s):  
Johanna Hartung ◽  
Martina Bader ◽  
Morten Moshagen ◽  
Oliver Wilhelm
Keyword(s):  
Personality Traits ◽  
Structural Equation ◽  
Age Groups ◽  
Dark Triad ◽  
Equation Modeling ◽  
Model Parameters ◽  
Age And Gender ◽  
Measurement Models ◽  
And Gender ◽  
Latent Means

The strong overlap of personality traits discussed under the label of “dark personality” (e.g., psychopathy, spitefulness, moral disengagement) endorses a common framework for socially aversive traits over and beyond the dark triad. Despite the rapidly growing research on socially aversive traits, there is a lack of studies addressing age-associated differences in these traits. In the present study ( N = 12,501), we investigated the structure of the D Factor of Personality across age and gender using local structural equation modeling, thereby expressing the model parameters as a quasi-continuous, nonparametric function of age. Specifically, we evaluated loadings, reliabilities, factor (co-)variances, and means across 35 locally weighted age groups (from 20 to 54 years), separately for females and males. Results indicated that measurement models were highly stable, thereby supporting the conceptualization of the D factor independent of age and gender. Men exhibited uniformly higher latent means than females and all latent means decreased with increasing age. Overall, D and its themes were invariant across age and gender. Therefore, future studies can meaningfully pursue causes of mean differences across age and between genders.

Ttrimetyllysine and risk of new-onset atrial fibrillation in two large norwegian cohorts

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
MM Svenningsson ◽  
I Dhar ◽  
GFT Svingen ◽  
EKR Pedersen ◽  
D Nilsen ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Angina Pectoris ◽  
Coronary Angiography ◽  
Stable Angina ◽  
Cox Regression ◽  
Health Study ◽  
Stable Angina Pectoris ◽  
Age And Gender ◽  
And Gender ◽  
New Onset

Abstract Funding Acknowledgements Type of funding sources: None. Background/Aim Increased plasma trimetyllysine (TML), a methylated amino acid, has recently been linked to higher risk of acute myocardial infarction (AMI). TML is also a precursor of trimethylamine-N oxide (TMAO), which has been linked to increased cardiovascular risk, including that of  atrial fibrillation (AF). We investigated the association between TML and new-onset AF in two large Norwegian cohorts. Methods The primary cohort consisted of 6396 participants in the community-based Hordaland Health Study (HUSK). The validation cohort consited of 2027 patients who underwent coronary angiography due to suspected stable angina pectoris in the Western Norway Coronary Angiography Cohort (WECAC). Information on new-onset AF was obtained by linking patient data to Norwegian public health registries. Risk associations were explored by Cox regression. Results During median (25th-75th percentile) follow-up of 10.9 (10.6-11.3) and 7.0 (6.3-8.6) years, 560 (8.8%) patients in the HUSK and 210 (10.4%) in the WECAC was diagnosed with AF. In the HUSK, the age and gender adjusted HR (95 % CI) for the 4th vs. 1st plasma TML quartiles 1.84 (1.37-2.48) p &lt; 0.001. In multivariable models the association was only slightly attenuated. Correspondingsly, the age and gender adjusted HR (95% CI) for the 4th vs. 1st TML quartiles in the WECAC was 1.48 (0.96-2.27) p = 0.07. Testing for collinearity between TMAO and TML revealed variance inflation factors between 1.0-1.1 in HUSK and WECAC, thus ruling out collinearity. Conclusion Plasma TML was associated with new-onset AF among subjects from the general population, and the relationship was independent from established AF risk factors. A similar trend was also seen in patients with suspected stable angina pectoris, strengthening our findings, which motivate further studies to explore potential pathophysiological relationships between one-carbon metabolism and cardiac arrhythmias

scholarly journals Biomarker potential of lncRNA GNAS-AS1 in osteosarcoma prognosis and effect on cellular function

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Zhanhu Mi ◽  
Yanyun Dong ◽  
Zhibiao Wang ◽  
Peng Ye
Keyword(s):  
Cell Proliferation ◽  
Cell Function ◽  
Cox Regression ◽  
Bone Cancer ◽  
Prognostic Indicator ◽  
Migration And Invasion ◽  
Rank Test ◽  
Chi Square ◽  
Invasion And Migration ◽  
Novel Therapeutic Strategies

Abstract Background Osteosarcoma (OS) is a type of bone cancer that occurs in children and adolescents at a rate of 5%. The purpose of this study is to explore the lncRNA GNAS-AS1 expression profile, prognosis significance in OS, and biological effect on OS cell function. Methods One hundred eight pairs of tissues were collected, and OS cell lines were purchased. lncRNA GNAS-AS1 expression in these tissues and cells were analyzed by qRT-PCR. Clinical data were analyzed using chi-square tests, Kaplan-Meier curves (log-rank test), and Cox regression. CCK-8 and transwell assay were conducted to analyze the effect of lncRNA GNAS-AS1 on cell proliferation, invasion, and migration. The downstream miRNA was presumed. Results The expression of lncRNA GNAS-AS1 was significantly increased in OS cells and tissues, and related to Enneking staging and distant metastasis. Patients with high lncRNA GNAS-AS1 expression represented shorter overall survival and was an independent prognostic predictor of OS. LncRNA GNAS-AS1 knockdown inhibited cell proliferation, migration, and invasion by regulated miR-490-3p partly at least. Conclusions LncRNA GNAS-AS1 can be used as a prognostic indicator and its inhibition suppress the development of OS, suggesting its value as novel therapeutic strategies in OS.

scholarly journals Exploring Impact of Age and Gender on Sentiment Analysis Using Machine Learning

Electronics ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 374 ◽  
Author(s):  
Sudhanshu Kumar ◽  
Monika Gahalawat ◽  
Partha Pratim Roy ◽  
Debi Prosad Dogra ◽  
Byung-Gyu Kim
Keyword(s):  
Machine Learning ◽  
Sentiment Analysis ◽  
Short Term Memory ◽  
Age Groups ◽  
Modern World ◽  
Support Vector ◽  
Digital Information ◽  
Age And Gender ◽  
And Gender ◽  
The Impact

Sentiment analysis is a rapidly growing field of research due to the explosive growth in digital information. In the modern world of artificial intelligence, sentiment analysis is one of the essential tools to extract emotion information from massive data. Sentiment analysis is applied to a variety of user data from customer reviews to social network posts. To the best of our knowledge, there is less work on sentiment analysis based on the categorization of users by demographics. Demographics play an important role in deciding the marketing strategies for different products. In this study, we explore the impact of age and gender in sentiment analysis, as this can help e-commerce retailers to market their products based on specific demographics. The dataset is created by collecting reviews on books from Facebook users by asking them to answer a questionnaire containing questions about their preferences in books, along with their age groups and gender information. Next, the paper analyzes the segmented data for sentiments based on each age group and gender. Finally, sentiment analysis is done using different Machine Learning (ML) approaches including maximum entropy, support vector machine, convolutional neural network, and long short term memory to study the impact of age and gender on user reviews. Experiments have been conducted to identify new insights into the effect of age and gender for sentiment analysis.

scholarly journals Performance of Children in Phonemic and Semantic Verbal Fluency Tasks

Psico-USF ◽  
2016 ◽  
Vol 21 (2) ◽  
pp. 293-304 ◽  
Author(s):  
Gilmara de Lucena Leite ◽  
Izabel Augusta Hazin Pires ◽  
Laura Carolina Lemos Aragão ◽  
Artemis Paiva de Paula ◽  
Ediana Rossely de Oliveira Gomes ◽  
...  
Keyword(s):  
Explicit Memory ◽  
Verbal Fluency ◽  
Age Groups ◽  
Memory Systems ◽  
Semantic Fluency ◽  
Age And Gender ◽  
Northeast Region ◽  
Semantic Verbal Fluency ◽  
And Gender ◽  
Brazilian Northeast

Abstract This study investigated the performance of children from the Brazilian Northeast region, from 7 to 10 years in phonemic and semantic verbal fluency tasks. The participants were 102 subjects (62 girls and 40 boys) who performed three phonemic and three semantic fluency tasks. The results were submitted to correlational and variance analysis to investigate the influence of the variables age and gender on the subjects performance. There was no effect of gender on the results. Significant contrasts between age groups were found, and better performance was observed on phonemic tasks. Also, the performance in this task changed along development, in contrast to what happened with the semantic fluency. The findings seem to be in accordance to neurodevelopmental aspects, taken into account that explicit memory systems show more precocious maturational course, with earlier consolidation, in comparison to the executive functions and frontal lobes, which go on developing until adult ages.

Thinking about ethnicity and gender diversity in children and young people

2018 ◽  
Vol 24 (2) ◽  
pp. 291-303 ◽  
Author(s):  
Nastasja M de Graaf ◽  
Ilham I Manjra ◽  
Anna Hames ◽  
Claudia Zitz
Keyword(s):  
Young People ◽  
Identity Development ◽  
Gender Identity ◽  
Gender Diversity ◽  
Age Groups ◽  
Chi Square ◽  
Children And Young People ◽  
And Gender ◽  
The Uk ◽  
Ethnicity Data

Background: Little is known about how social and cultural variants interact with gender identity development. This article aims to identify the ethnicities of children and young people referred to the United Kingdom’s national Gender Identity Development Service (GIDS), and compare the ethnicity data with the UK child population and referrals to Child and Adolescent Mental Health Services (CAMHS). Methods: GIDS referrals made between April 2012 and April 2015 for children and young people were retrieved. Ethnicity data were obtained by the ‘16 + 1’ ethnicity list. Chi-square and t-tests were performed on the demographics. Results: Less than 10% of the 995 referrals at GIDS were from Black and minority ethnic (BME) groups – an underrepresentation as compared with both the national population and CAMHS figures. No significant differences in ethnic representation were found between the demographic birth-assigned sexes, across age groups, or year of referral. Conclusions: Hypotheses proposed for this underrepresentation take into account both the potential barriers to accessing services and the possibility of cross-cultural variations in the conceptualisations of gender, gender roles and gender diversity. Ethnicity, culture and religion, and their overlapping relationship with gender need further exploration.

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