Network-Related Changes in Neurotransmitters and Seizure Propagation During Rodent Epileptogenesis

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011846
Author(s):  
Roni Dhaher ◽  
Shaun E. Gruenbaum ◽  
Mani Ratnesh S. Sandhu ◽  
Sigrid Ottestad-Hansen ◽  
Nathan Tu ◽  
...  
Keyword(s):  
Network Formation ◽  
Brain Regions ◽  
Mesial Temporal Lobe Epilepsy ◽  
T Test ◽  
Methionine Sulfoximine ◽  
Propagation Time ◽  
Seizure Focus ◽  
Spontaneous Seizures ◽  
Seizure Propagation ◽  
Paired T Test

Objective:To test the hypothesis that glutamate and GABA are linked to the formation of epilepsy networks and the triggering of spontaneous seizures, we examined seizure initiation/propagation characteristics and neurotransmitter levels during epileptogenesis in a translationally relevant rodent model of mesial temporal lobe epilepsy.Methods:The glutamine synthetase (GS) inhibitor methionine sulfoximine was infused into one of the hippocampi in laboratory rats to create a seizure focus. Long-term video-intracranial EEG recordings and brain microdialysis combined with mass spectrometry were used to examine seizure initiation, seizure propagation, and extracellular brain levels of glutamate and GABA.Results:All seizures (n = 78 seizures, n = 3 rats) appeared first in the GS-inhibited hippocampus of all animals, followed by propagation to the contralateral hippocampus. Propagation time decreased significantly from 11.65 seconds early in epileptogenesis (weeks 1-2) to 6.82 seconds late in epileptogenesis (weeks 3 – 4, paired t-test, p = 0.025). Baseline extracellular glutamate levels were 11.6-fold higher in the hippocampus of seizure propagation (7.3 µM) vs. the hippocampus of seizure onset (0.63 µM, ANOVA/Fisher’s LSD, p = 0.01), even though the concentrations of the major glutamate transporter proteins EAAT1, EAAT2 and xCT were unchanged between the brain regions. Finally, extracellular GABA in the seizure focus decreased significantly from baseline several hours before a spontaneous seizure (paired t-test/FDR).Conclusion:The changes in glutamate and GABA suggest novel and potentially important roles of the amino acids in epilepsy network formation and in the initiation and propagation of spontaneous seizures.

Efektivitas Aroma Terapi Lemon untuk Menangani Emesis Gravidarum

2019 ◽  
Vol 11 (4) ◽  
pp. 277-284
Author(s):  
Vitrianingsih Vitrianingsih ◽  
Sitti Khadijah
Keyword(s):  
Pregnant Women ◽  
Sampling Technique ◽  
T Test ◽  
The Body ◽  
Nausea And Vomiting ◽  
P Value ◽  
Purposive Sampling ◽  
Body Tissues ◽  
Quasi Experimental ◽  
Paired T Test

Studi memperkirakan emesis gravidarum terjadi pada 50-90% kehamilan. Mual muntah pada kehamilan memberikan dampak yang signifikan bagi tubuh dimana ibu menjadi lemah, pucat dan cairan tubuh berkurang sehingga darah menjadi kental (hemokonsentrasi). Keadaan ini dapat memperlambat peredaran darah dan berakibat pada kurangnya suplay oksigen serta makanan ke jaringan sehingga dapat membahayakan kesehatan ibu dan janin. Salah satu terapi yang aman dan dapat dilakukan untuk mengurangi keluahan mual muntah pada ibu hamil adalah pemberian aromaterapi lemon. Penelitian bertujuan untuk mengetahui efektifitas aroma terapi lemon untuk menangani emesis gravidarum. Penelitian ini menggunakan rancangan Quasi experiment  dengan  one group pre-post test design. Populasi penelitian adalah ibu hamil yang mengalami emesis gravidarum di Kecamatan Berbah, Sleman. Jumlah sampel 20 ibu hamil trimester pertama yang diambil dengan teknik purposive sampling. Pengukuran mual muntah dilakukan debelum dan setelah  pemberian aromaterapi lemon menggunakan Indeks Rhodes. Analisa data menggunakan uji Paired t-test. Hasil penelitian didapatkan rata-rata skor mual muntah sebelum pemberian aromaterapi lemon berdasarkan Indeks Rhodes pada Ibu Hamil dengan emesis gravidarum yaitu 22,1 dan terjadi penurunan skor setelah pemberian aromaterapi lemon menjadi 19,8. Ada pengaruh pemberian aromaterapi lemon dengan pengurangan mual muntah pada ibu hamil (p-value = 0.017). Berdasarkan hasil penelitian dapat disimpulkan pemberian aromaterapi lemon efektif untuk mengurangi emesis gravidarum pada ibu hamil trimester pertama.  Kata kunci: aromaterapi lemon, emesis gravidarum THE EFFECTIVENESS OF LEMON AROMATHERAPY FOR HANDLING EMESIS GRAVIDARUM   ABSTRACT Studies estimate that nausea and vomiting (emesis gravidarum) occur in 50 – 90% of pregnancies. Nausea and vomiting of pregnancy have a significant impact on the body in which it makes a mother becomes weak, pale, and decreasing body fluid so that the blood becomes thick (hemoconcentration). This situation can slow down blood circulation and inflict the lack of oxygen and food supplies to the body tissues so that it can endanger the health of the mother and fetus. One of the therapies that is safe and can be conducted to reduce nausea and vomiting of pregnancy is by giving the lemon aromatherapy treatment. The research aims to determine the effectiveness of the aroma of lemon therapy to deal with emesis gravidarum. This study applied quasi-experimental research with one group pretest-posttest design. The population of this study was pregnant women who experienced emesis gravidarum. Furthermore, samples were 20 mothers from Berbah, Sleman taken by using a purposive sampling technique. Nausea and vomiting were assessed between before and after giving lemon aromatherapy using the Rhodes Index. The data were analyzed using the paired t-test. The mean score of nausea and vomiting before giving lemon aromatherapy on mother with emesis gravidarum based on the Rhodes Index was 22.1. However, it decreased after given lemon aromatherapy treatment to 19.8. Therefore, there was an effect on giving lemon aromatherapy treatment toward the decrease of nausea and vomiting for pregnant women (p-value = 0.017). Lemon aromatherapy is effective to reduce emesis gravidarum.  Keywords: lemon aromatherapy, emesis gravidarum

PENGARUH PRACTICE BASED SIMULATION MODEL TERHADAP CRITICAL THINKING DI NURSING SKILL LABORATORY

2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Retno Issroviatiningrum ◽  
Shanti Wardaningsih ◽  
Novita Kurnia Sari
Keyword(s):  
Critical Thinking ◽  
Simulation Model ◽  
Random Sampling ◽  
Simple Random Sampling ◽  
T Test ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Skill Laboratory ◽  
Paired T Test

ABSTRAK Upaya untuk meningkatkan mutu pendidikan keperawatan khususnya untuk mendukung peserta didik menjadi perawat profesional memerlukan proses pembelajaran dengan menggunakan fasilitas keterampilan klinis. Practice based simulation model didasarkan pada teori belajar konstruktif yang menegaskan bahwa pengetahuan tidak pasif ditransfer dari pendidik kepada peserta didik, tetapi dibangun oleh peserta didik melalui pengolahan pengalaman dan interaksi dengan lingkungan mereka. Dengan metode simulasi di laboratorium dapat mendorong mahasiswa untuk menggunakan critical thinking dalam mengambil keputusan dalam mengatasi masalah tanpa merugikan pasien yang sebenarnya. Penelitian ini bertujuan untuk menganalisis pengaruh practice based simulation model terhadap critical thinking pada mahasiswa semester VI di FIK Unissula Semarang. Penelitian ini menggunakan metode Quasy – Experiment dengan pendekatan pretest-posttest with control group design. Pengambilan sampel dengan teknik  simple random sampling dengan jumlah 21 responden baik kelompok intervensi maupun kelompok kontrol. Analisis data menggunakan uji Paired T-Test dan Independent Samples T-Test. Hasil penelitian selisih peningkatan critical thinking pada kelompok intervensi sebanyak 11.95 poin dan pada kelompok kontrol 2.05. Practice based simulation model berpengaruh terhadap critical thinking dengan nilai p=0.00<0.05. Disimpulkan bahwa practice based simulation model mempengaruhi critical thinking pada mahasiswa semester VI FIK Unissula Semarang. Kata kunci: Practice based simulation model, critical thinking

Pengaruh media teka-teki silang terhadap pengetahuan gizi seimbang pada anak sekolah dasar

2019 ◽  
Vol 2 (2) ◽  
pp. 107
Author(s):  
Umi Mahmudah
Keyword(s):  
T Test ◽  
Control Group ◽  
Paired T Test ◽  
Quasi Experiment

Latar Belakang: Anak-anak sekolah dasar merupakan salah satu kelompok rawan masalah gizi, baik pada gizi kurang maupun gizi lebih. Pendidikan gizi seimbang perlu diterapkan untuk mengatasi masalah gizi tersebut. Metode pendidikan mendorong peran serta dan keterlibatan anak untuk memberikan motivasi dalam belajar. Berbagai metode pendidikan yang menarik bagi anak antara lain permainan, tebak-tebakan, diskusi kelompok, serta peragaan. Tujuan: Untuk mengetahui pengaruh pendidikan gizi menggunakan media teka-teki silang (TTS) terhadap pengetahuan gizi seimbang pada anak sekolah dasar. Metode: Penelitian ini merupakan penelitian quasi experiment dengan rancangan pre-posttest with control group. Penelitian dilakukan pada anak Sekolah Dasar Negeri Donohudan I. Pengukuran pengetahuan gizi seimbang dilakukan sebanyak dua kali, yaitu pretest dan posttest. Penelitian ini dibagi menjadi dua kelompok, yaitu kelompok intervensi yang diberikan pendidikan gizi menggunakan teka-teki silang dan kelompok kontrol yang diberikan pendidikan gizi menggunakan ceramah. Pengukuran pengetahuan pretest dilakukan sebelum diberikan pendidikan gizi dan pengukuran pengetahuan posttest diberikan setelah dilakukan pendidikan gizi. Data dianalisis menggunakan Paired T-test dan Independent Sample T-test. Hasil: Terdapat perbedaan pengetahuan sebelum dan setelah dilakukan pendidikan gizi menggunakan media TTS dan media ceramah (p=0,010). Rerata peningkatan pengetahuan gizi menggunakan media TTS lebih tinggi dibandingkan dengan menggunakan metode ceramah pada anak sekolah dasar. Kesimpulan: Ada pengaruh pengetahuan gizi seimbang sebelum dan setelah diberikan pendidikan gizi, baik menggunakan media teka-teki silang maupun menggunakan media ceramah.

LIFE REVIEW THERAPY MENURUNKAN TINGKAT DEPRESI LANSIA PADA WARGA BINAAN SOSIAL DI PANTI SOSIAL TRESNA WERDHA BUDI MULIA 3 JAKARTA SELATAN

2020 ◽  
Vol 15 (2) ◽  
pp. 114-121
Author(s):  
Maryati . ◽  
Eka Rokhmiati Wahyu Purnamasari
Keyword(s):  
Control Design ◽  
Life Review ◽  
T Test ◽  
Post Test ◽  
Life Review Therapy ◽  
Paired T Test ◽  
Quasi Experiment

Life Review Therapy merupakanterapi psikoterapi untuk menyelesaikan masalah pada lansia yang mengalami depresi, mengekspresikan perasaan yang disupresikan sehingga energy psikis tersebut dilepaskan. Tujuan penelitian ini untuk mengetahui pengaruh Life Review Therapy terhadap tingkat depresi lansia pada warga binaan sosial di PSTW Budi Mulia Jakarta Selatan.Metode yang digunakan adalah quasi experiment, dengan pendekatan Pre Test and Post Test Without Control design. Populasi dalam penelitian ini adalah lansia dengan jumlah sampel 20 orang dengan teknik purposivesampling. Analisis data menggunakan Paired T Test dengan tingkat signifikan (α0,05). Hasil menunjukan bahwa ada pengaruh Life Review Therapy terhadap tingkat depresi lansiadengan ρValue=0,000. Berdasarkan penelitian tersebut, terapi Life Reviewterbukti dapat menurunkan tingkat depresi sehingga terapi ini dapat dijadikan salah satu acuan terapi untuk menangani depresi pada lansia di PSTW

PENGARUH HEALTH EDUCATION TERHADAP KEPATUHAN PERILAKU HIDUP BERSI SEHAT (PHBS) WARGA

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Tatiana Siregar ◽  
Nelly Febriani
Keyword(s):  
Health Education ◽  
T Test ◽  
P Value ◽  
Purposive Sampling ◽  
Post Test ◽  
Paired T Test ◽  
Quasi Experiment

Latar belakang: Kondisi sasaran pencapaian Indonesia Sehat 2015 dari program MDG’s yang belum tercapai, sehingga dilanjutkan dengan program SDGs menjadikan Indonesia harus banyak berperan dalam semua kegiatan khsusnya di bidang kesehatan. Proses pencapaian cakupan program kesehatan sangat dipengaruhi oleh Health education yang dilakukan petugas kesehatan kepada warga, kesehatan masyarakat. Tujuan: Penelitain ini bertujuan untuk mengetahui perubahan perilaku hidup bersih sehat yang  dilaksanakan warga setelah diberikan intervesi health education.  Metode: Metode penelitian dilaksanakan secara quasi experiment pre dan post test.  Teknik mengambil sampel secara purposive Sampling pada 30 reponden kelompook intervensi dan 26 responden kelompok kontrol. Analisa data dilakukan secara paired t test. Hasil: Hasil di dapat ada perbedaan yang bermakna antara pengetahuan dan perubahan perilaku hidup bersih sehat repsonden sebelum dan sesudah diberi penyuluhan p value = 0,000. Saran: Diharapkan pemerintah setempat menggerakkan petugas kesehatan bersama-sama dengan warga melakukan perilaku hidup bersih sehat dalam kehidupan sehari-hari dengan memfasilitasi  sarana penunjang untuk menjalankan perilaku hidup bersih sehat, dengan maksimal pada warga. Kata kunci: Health eduation,  Perilaku Hidup Bersih Sehat

PENGARUH MEDIA GAMBAR TERHADAP KEMAMPUAN MENULIS PUISI SISWA

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sinta Maria Dewi
Keyword(s):  
Design Method ◽  
Writing Skills ◽  
Class Action ◽  
T Test ◽  
Control Group ◽  
Control Group Design ◽  
Media Image ◽  
Group Design ◽  
Random Method ◽  
Paired T Test

Abstract: This research aims to know the Influence of Media Image on the ability of Writing Poetry students. The method used in this study is a random method that does not use posttes control group design method. The findings of this study show the average way of writing poetry on students by using the image media (experimental class) higher average poetry writing skills on students who were taught with conventional learning (control class). The average of pretest experiments obtained by experiment class is 63,75. The average pretest class of control class is 61,05. After the second class action, the average posttest of the experimental class is 79.45 and the control class is 74.95. Hypothesis calculation using t paired t test test and significance of 0.05 significant level indicates probability (significance) is 0,033. Because of the significance of 0.033

Efektifitas Air Rebusan Daun Seledri Terhadap Perubahan Tekanan Darah Pada Lansia di Posyandu Ngudi Konco Desa Donomulyo Kecamatan Donomulyo Kab. Malang

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Hartin Suidah ◽  
Ninik Murtiyani ◽  
Arif Susanto ◽  
Yufi Aris Lestari ◽  
Shindy Sofyaning Fitra
Keyword(s):  
Blood Pressure ◽  
Sampling Technique ◽  
The Elderly ◽  
Reduce Blood Pressure ◽  
T Test ◽  
Boiling Water ◽  
Test Design ◽  
Post Test ◽  
Boiled Water ◽  
Paired T Test

ABSTRAKMasih tingginya penderita hipertensi merupakan salah satu masalah yang berpengaruh terhadap gaya hidup dan sikap yang mendorong timbulnya hipertensi. Untuk menangani tekanan darah pada penderita hipertensi umumnya minum obat-obatan dari puskesmas, rutinitas ini sering tidak disukai oleh penderita. Penelitian ini bertujuan untuk mengetahui efektifitas air rebusan daun seledri terhadap perubahan tekanan darah pada lansia di Posyandu Ngudi Konco Desa Donomulyo Kecamatan Donomulyo Kabupaten Malang.Desain penelitian ini Pre-Experimental dengan rancangan One- Group Pre-Post test design. Populasi dalam penelitian ini adalah semua lansia penderita hipertensi di Posyandu Ngudi Konco Desa Donomulyo Kecamatan Donomulyo Kabupaten Malang sebanyak 30 responden. Sampel diambil dengan teknik total sampling. Variabel penelitian yaitu pemberian air rebusan daun seledri sebagai variabel independent dan tekanan darah sebagai variabel dependen. Data yang di dapat melalui lembar observasi tekanan darah kemudian di uji dengan menggunakan uji paired t Test.Hasil uji paired t Test menunjukkan bahwa p = 0,000 α= 0,05 Ho di tolak dan H1 diterima sehingga air rebusan daun seledri efektif terhadap perubahan tekanan darah pada lansia di Posyandu Ngudi Konco Desa Donomulyo Kecamatan Donomulyo Kabupaten Malang.Terdapat penurunan jumlah penderita hipertensi sebelum dan sesudah diberikan air rebusan daun seledri. Responden agar dapat meningkatkan informasi tentang pelaksanaan tekanan darah sehingga dapat mengurangi tekanan darah yang dialami dengan cara non formakologi sehingga responden tidak hanya menggantungkan pada obat-obatan farmakologi dalam menurunkan tekanan darah.Kata kunci : Air Rebusan Daun Seledri, Tekanan Darah, Lansia ABSTRACTStill high hypertension was  one of the problems that affect the lifestyle and attitudes that encourage the emergence of hypertension. To handle blood pressure in people with hypertension generally take  medication from puskesmas, this routine was often disliked by the patient. This study aims to determine the effectiveness of boiling water celery leaves on changes in blood pressure in the elderly at Posyandu Ngudi Konco Donomulyo Village Donomulyo District Malang Regency.The design of this research was  Pre-Experimental with the design of One- Group Pre-Post test design. Population in this research was all elderly patient of hypertension in Posyandu Ngudi Konco Village Donomulyo District Donomulyo Malang Regency as many as 30 respondents. Samples were taken with total sampling technique. The research variable was giving boiled water of celery leaves as independent variable and blood pressure as dependent variable. The data can be through blood pressure observation sheet then tested by using paired t test.The result of paired t - test showed that p = 0.000 α = 0.05 Ho in rejection and H1 accepted so that boiling water celery leaf effective against blood pressure changes in elderly at Posyandu Ngudi Konco Donomulyo Village Donomulyo District Malang Regency. There was a decrease in the number of hypertensive patients before and after being given boiled water of celery leaves. Respondents in order to improve information about the implementation of blood pressure so as to reduce blood pressure experienced by non-formakologi way so that respondents not only rely on pharmacological drugs in lowering blood pressure. Key Words: Water Stew of Celery leaves, Blood Pressure, Elderly

Digital volumetric measurements based on 3D scans of the lower limb: A valid and reproducible method for evaluation in lymphedema therapy. (Preprint)

2019 ◽  
Author(s):  
Daniel Schiltz ◽  
Natalie Kiermeier ◽  
Dominik Eibl ◽  
Christoph Koch ◽  
Karolina Müller ◽  
...  
Keyword(s):  
Lower Limb ◽  
Lower Leg ◽  
T Test ◽  
Volume Changes ◽  
Quick Method ◽  
Reproducible Method ◽  
The Mean ◽  
3D Scans ◽  
Paired T Test ◽  
Volumetric Measurements

BACKGROUND Exact quantification of volumetric changes of the extremities is difficult. There are several direct and indirect methods to assess extremity volume. As water displacement volumetry is rarely viable in a clinical setting and circumference measurements are prone to errors due to poor reproducibility and high inter- and intra-observer variability, an objective and easily reproducible method is indispensable. OBJECTIVE The aim of this study was to establish a standardized method based on 3D scans with defined caudal and cranial landmarks of the lower leg which allows for measurements of exactly the same body area. Furthermore, this study tests the method in terms of reproducibility and evaluates volume changes after surgical therapy in patients suffering from lymphedema. METHODS 3D-scans of the lower limb were performed with a mobile 3D-scanner. Volumetric calculation was done digitally. “Repeatability“ and “Inter-observer reliability” of digital volumetry were tested. Furthermore, the method was applied on 31 patients suffering from chronic lymphedema. ANOVA (analyses of variance) was conducted to compare the digital volumetric measurements. To assess the sensitivity to changes in digital volumetry, the mean volume of 31 patients before and 3 months after therapy were compared by a paired t-Test. RESULTS Calculations of repeatability of the volume based on 20 3D-scans of the same lower leg showed a mean volume of 2,488 ± 0,011 liters (range: 2,470 – 2,510). The mean volume of the 7 measurements of the 3 examiners did not differ significantly (F(2,18) = 1,579, p = .233). The paired t-Test showed a significant mean volume decrease of 375ml (95% CI = 245/505ml) between pre and post treatment (t (30) =5,892, p < .001). CONCLUSIONS 3D-Volumetry is a noninvasive, easy and quick method to assess volume changes of the lower leg. Other than the costs, it is reproducible and precise and therefore ideal for evolution of therapy in lymphedema.

The effect of positive thinking training on the quality of life of parents of adolescent with thalassemia

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Adeleh Sadeghloo ◽  
Parna Shamsaee ◽  
Elham Hesari ◽  
Golbanhar Akhondzadeh ◽  
Hamid Hojjati
Keyword(s):  
Quality Of Life ◽  
Emotional Health ◽  
Intervention Group ◽  
T Test ◽  
World Health ◽  
Positive Thinking ◽  
Significant Difference ◽  
And Control ◽  
Paired T Test

Abstract Introduction Thalassemia, as the most common chronic hereditary blood disorder in humans, can impose many adverse effects on parents and their affected children. On the other hand, positive thinking is the method or the result of a positive focus on a constructive issue, so by teaching positive thinking, we can improve physical and social function, and promote emotional health and overall quality of life. The aim of this study was to determine the effect of positive thinking training on the quality of life of parents of adolescents with thalassemia. Methods This quasi-experimental study was performed on 52 parents of adolescents with thalassemia who attended Taleghani Hospital in Golestan province, Iran in 2017. Samples were randomly assigned into two groups of intervention and control. The positive thinking training (based on the theory of Martin Seligman) was carried out in the intervention group in 10 (45–60 min) sessions over a 5-week period. Data collection tools in this study were the World Health Organization (WHO) quality of life questionnaire (WHOQOL-BREF) and a demographic information questionnaire. Data were analyzed by SPSS-16 software using independent t-test, the paired t-test and a covariance test. Results The results of paired t-test showed a significant difference in the score of quality of life in intervention group before and after the intervention (p < 0.001). However, this test did not show any significant difference in the control group (p = 0.11). The covariance test, after removing the pre-test score, showed a significant difference between the intervention and control groups in terms of the score of quality of life, so that 13% of the changes after the intervention were due to the intervention (p = 0.009, η = 0.13). Conclusion The positive thinking training increased the quality of life of parents of adolescents with thalassemia. Therefore, using this program can be an effective way of improving the quality of life of parents. Thus, positive thinking training is suggested to be used as an effective strategy for increasing the quality of life of parents with ill children.

scholarly journals KEBUGARAN FISIK SISWA RETARDASI MENTAL RINGAN SEKOLAH DASAR LUAR BIASA KUNCUP BUNGA DENPASAR LEBIH TINGGI SESUDAH MELAKUKAN PELATIHAN SENAM PINGUIN DARI PADA SENAM RIA ANAK INDONESIA

2018 ◽  
Author(s):  
I Putu Eka Jaya ◽  
Nyoman Mangku Karmaya ◽  
Made Jawi ◽  
Wayan Weta ◽  
Ida Bagus Ngurah ◽  
...  
Keyword(s):  
Physical Fitness ◽  
Test Group ◽  
T Test ◽  
Percentage Increase ◽  
Test Results ◽  
Physical Fitness Test ◽  
Fitness Test ◽  
Group 2 ◽  
Paired T Test ◽  
Group 1

Physical fitness is ability to perform the activity or activities without feeling tired excessively. Physical fitness associated with a person`s organs to carry out its tasks properly every day without experiencing significant fatigue. In a child’s mental retardation with a les mobile lifestyle that will affect his physical fitness. The purpose of this study to determine which type of gymnastic exercise better to the physical fitness on the students in Sekolah Dasar Luar Biasa Kuncup Bunga Denpasar.This research used experimental method using Randomized study Pre and Post Test Group Design. The subjects in this study were students in Sekolah Dasar Luar Biasa Kuncup Bunga Denpasar. There were 18 students which is divided into two groups: group-1 is senam penguins and group-2 is senam ria anak Indonesia. Data were obtained after a six-week training analyzed by paired t-test and unpaired t-test.The results of physical fitness test before training with Senam Penguins was 23.39 ± 1.69 and the test results after the training was 27.87 ± 3.28. the physical fitness test in group-2 before training with Senam Ria anak Indonesia was 22.69 ± 1.76 and the results after training was 24.64 ± 2.11. Paired t-test in both group before and after training showed significant differences after training in group-1 and group-2 with a value of p > 0.05 with an increase in physical fitness test results of (19.15) in group-1 and (8.64) in group-2. The percentage increase physical fitness test results of group-1 with senam penguins is higher than those in group-2 with senam ria anak Indonesia.So we can conclude that the training of senam penguin in Sekolah Dasar Luar Biasa Kuncup Bunga Denpasar improved the physical fitness test results higher than senam ria anak Indonesia.

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