scholarly journals Serum Immunoglobulin E and Serotonin levels in Chronic Supporative Otitis Media Patients with and without treatment

2021 ◽  
Vol 37 (5) ◽  
Author(s):  
Shafaque Mehboob Khan ◽  
SM Tariq Rafi ◽  
MS Mehjabeen Mehjabeen ◽  
Hurtimania Khan
Keyword(s):  
Otitis Media ◽  
Immunoglobulin E ◽  
Positive Control ◽  
Serum Immunoglobulin ◽  
Negative Group ◽  
Healthy Individuals ◽  
Tukey Test ◽  
Significant Difference ◽  
Post Hoc ◽  
One Way Anova

Objective: To determine the serum immunoglobulin E and serotonin levels of patients with chronic suppurative otitis media (CSOM) with and without treatment. Methods: This is a case-control study carried out in ENT ward of Jinnah Postgraduate Medical Centre Karachi Pakistan from May to September 2018.. Sample (n=160) was divided into four groups (40 individuals per group) as G1: control negative (group-1 without any disease), G2: positive control (patients didn’t received medicines), G3: group (patients treated with co-amoxicillin 1000mg per day) and G4: group (patients treated with ciprofloxacin1000mg per day). After treatment period of One week serum immunoglobulin E and serotonin concentrations were evaluated by Elisa method at 450nm. Statistical evaluation was carried out using one-way ANOVA (p<0.05) followed by post hoc (tukey test) for further group comparison. In order to find out correlation between IgE and serotonin with CSOM Pearson’s correlation was applied. Results: There was no significant (p>0.05) association found between genders with serotonin as well as with IgE levels in CSOM patients. One way ANOVA showed significant difference (p<0.05) for IgE and serotonin levels and post hoc (tukey test) showed significant higher of IgE levels in CSOM patients of G2 positive control (diseased patients) was observed when compared to the control negative group (healthy individuals) and also from treated groups of G3 and G4. This also showed that serotonin levels were significantly low in G2 (positive control) as well as in treated groups of G3 and G4 in contrast with healthy individuals of group G1. Conclusion: Antibiotics may revert the higher levels of IgE but cannot attenuate the decreased levels of neurotransmitter (serotonin) like healthy individuals, therefore, depression levels of CSOM patients should be monitored, scored and attenuated with proper intervention of antidepressants or counseling. doi: https://doi.org/10.12669/pjms.37.5.2414 How to cite this:Mehboob S, Rafi SMT, Mehjabeen, Khan H. Serum Immunoglobulin E and Serotonin levels in Chronic Supporative Otitis Media Patients with and without treatment. Pak J Med Sci. 2021;37(5):---------. doi: https://doi.org/10.12669/pjms.37.5.2414 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals PENGARUH KURMA (PHOENIX DACTYLIFERA L.) TERHADAP BERAT BADAN TIKUS PUTIH JANTAN (RATTUS NOVERGICUS)

2018 ◽  
pp. 181-188
Author(s):  
F Fadila ◽  
Brian Wasita ◽  
Paramasari Dirgahayu
Keyword(s):  
Positive Control ◽  
Negative Control ◽  
T Test ◽  
Test Weight ◽  
Control Group ◽  
Significant Difference ◽  
Post Test ◽  
Post Hoc ◽  
One Way Anova ◽  
Paired T Test

ABSTRAK Kurma merupakan salah satu buah dengan kandungan gizi terlengkap. Selain tinggi energi terutama karbohidrat (glukosa, fruktosa), kurma juga mengandung mineral besi yang berperan dalam metabolisme energi. Tujuan penelitian ini untuk mengetahui pengaruh kurma terhadap berat badan tikus (Rattus novergicus). Jenis penelitian eksperimental laboratorik dengan pre-post test with control grup. Sampel adalah 24 ekor tikus putih jantan (Rattus novergicus) strain Wistar, dibagi menjadi 4 kelompok, yaitu kelompok K1 (kontrol negatif), dan K2 (kontrol positif (diberikan suplemen FeSO )), P1 (perlakuan ekstrak air kurma mentah), dan P2 (perlakuan sari kurma). Analisis data dengan uji paired t-test untuk mengetahui perbedaan berat badan pre-post test, ANOVA untuk mengetahui perbedaan berat badan post test antar kelompok, yang dilanjutkan dengan post hoc test LSD, dengan α=0,01. Hasil penelitian menunjukan terjadi peningkatan berat badan pada semua kelompok sampel (K1, K2, P1, dan P2). Peningkatan berat badan tertinggi pada kelompok kontrol positif (K1) 11,12%, diikuti oleh kelompok perlakuan SK (P2) 11,00%, dan perlakuan EAKM (P1) 10,90%, sedangkan yang terendah pada kelompok kontrol negatif (K1) hanya 5,32%. Hasil analisis paired t-Test pada kelompok kontrol positif (K2), perlakuan EAKM (P1) dan SK (P2) menunjukan terdapat perbedaan berat badan pre- post test yang signifikan (p<0,01). Hasil analisis One Way Anova, diperoleh nilai p=0,000 (p<0,01) yang menandakan terdapat perbedaan berat badan post test yang signifikan antar 4 kelompok, di mana post hoc test LSD menunjukan perbedaan terletak antara kontrol negatif (K1) dengan kelompok yang diberikan perlakuan (K2, P1, dan P2), sedangkan diantara kelompok K2, P1, dan P2 tidak ada perbedaan yang signifikan. Kesimpulan: Kurma dapat meningkatkan berat badan tikus yang mengalami anemia defisiensi besi. Pengaruh kurma terhadap berat badan tikus sama dengan pengaruh dari pemberian suplemen FeSO4. Peningkatan berat badan tikus tanpa perlakuan sangat rendah jika dibandingkan dengan peningkatan berat badan tikus yang diberikan kurma dan suplemen FeSO .Kata Kunci: kurma (Pheonix dactylifera L.); ekstrak air kurma mentah (EAKM), sari kurma (SK), suplemen FeSO4, berat badan tikus. ABSTRACT Dates are one of the most nutritious fruits. In addition to high energy, especially carbohydrates, dates also contain iron minerals that play a role in energy metabolism. The purpose of this study was to determine the effect of dates on rat body weight (Rattus novergicus). Types of laboratory experimental studies with pre-post test with control group. The sample was 24 male white rats (Rattus novergicus) Wistar strain, divided into 4 groups, ie group K1 (negative control), and K2 (positive control (given FeSO4 supplement)), P1 (crude dates juice treatment), and P2 (dates juice treatment). Analysis of data with paired t-test to determine the difference of pre-post test weight, One Way Anova to know difference of post test between group weight, followed by post hoc test of LSD, with α = 0,01. The results showed that there was an increase in weight across all sample groups (K1, K2, P1, and P2). The highest weight gain in the positive control group (K1) was 11.12%, followed by the group of dates juice treatment (P2) 11.00%, and crude dates juice treatment (P1) 10.90%, while the lowest in the negative control group (K1) only 5 , 32%. The result of paired t-test analysis in positive control group (K2), crude dates juice treatment (P1) and dates juice treatment (P2) showed significant difference of pre-post test weight (p <0,01). The results of One Way Anova analysis showed that p = 0,000 (p <0,01) indicated that there was significant difference of post test weight between 4 groups, where post hoc test of LSD showed the difference between negative control (K1) and group that given treatment (K2, P1, and P2), whereas between groups K2, P1, and P2 there was no significant difference. Conclusion: Dates can increase the weight of rats with iron deficiency anemia. The effect of dates on body weight of rats is similar to that of FeSO4 supplementation. Increased rats weight without treatment is very low when compared with the increased weight of rats given dates and supplements of FeSO4.   Keywords: dates (Pheonix dactylifera L.); raw dates crude extract, dates juice, FeSO4 supplement, weight of rats.

An investigation of athletes' anxiety of catching Covid-19 and their motivation levels in terms of some variables

2021 ◽  
Vol 9 (4) ◽  
pp. 914-924
Author(s):  
Burkay Cevahircioğlu ◽  
Keyword(s):  
Achievement Motivation ◽  
Monthly Income ◽  
Tukey Test ◽  
Significant Difference ◽  
Gender Education ◽  
Education Status ◽  
New Type ◽  
Anxiety Levels ◽  
Post Hoc ◽  
One Way Anova

This study aims to examine the anxiety levels and motivation levels of athletes about catching covid-19 in terms of some variables. The sample group of the study consists of 204 women (51%) and 196 men (49%) in total, 400 athletes aged 18 and over, who are licensed in various branches. In the study, "Athletes' Anxiety of Catching New Type Coronavirus (Covid 19) Anxiety Scale (AAOCNTCAS)" developed by Tekkurşun Demir et al. (2020) and "Sport-Specific Achievement Motivation Scale" (SSAMS) developed by Willis (1982) and adapted in Turkish by Tiryaki and Gödelek (1997) are utilized. The Skewness-Kurtosis test was used to determine whether the data showed a normal distribution. As a result, t-test and One-Way Anova tests were used to analyze the data. The Post Hoc Tukey test was used for multiple comparisons. As a result of the research, A statistically significant difference was found between the demographic characteristics of the athletes’ anxiety about catching Covid-19 and their achievement motivation by, age, gender, education status, mother's education status, monthly income, athlete license category and total licensed sports year, while no statistically significant was found on paternal education status and type of sport. As a result of the findings, it is predicted that the anxiety levels of catching coronavirus may decrease by providing the necessary motivation to the athletes.

Perbedaan sensitivitas tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada otitis media supuratif kronik

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Anton Budhi Darmawan ◽  
Dwi Utami Anjarwati
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Test Results ◽  
Sectional Study ◽  
Suppurative Otitis Media ◽  
Number Of Patients ◽  
Significant Difference ◽  
Cochran Test ◽  
Post Hoc

Background: Chronic suppurative otitis media (CSOM) is one infectious disease of the middle ear, most commonly caused by Pseudomonas aeruginosa. A high number of patients come to the ENT outpatient clinic with active benign type of CSOM. The bacteria Pseudomonas aeruginosa is capable of producing biofilm which protects itself from penetration of antibiotics, and therefore creates resistance towards antibiotics and difficult to eradicate. Objective: The aim of this study was to compare the sensitivity levels of chloramphenicol, polymyxin-neomycin, cyprofloxacin and ofloxacine against Pseudomonas aeruginosa in patients with active benign type CSOM in ENT clinic. Method: The method used was across sectional study on 25 patients, from August 2010 until December 2010. Samples were taken withear swab and then put on sensitivity test to chloramphenicol, polymyxin-neomycin, cyprofloxacin andofloxacine using the diffusion disc method. The analysis used in this study was Cochran test. Results: Results showed a significant difference in sensitivity among chloramphenicol (38,70%), polymyxinneomycin(83,87%),cyprofloxacin(90,32%)andofloxacin(58,06%)withp=0,000(p<0,05).PostHocanalysisusing the Mc Nemar indicated that there were significant differences in sensitivity betweenpolymyxin-neomycin to chloramphenicol with p=0,000 (p<0,05), ciprofloxacin to chloramphenicol andciprofloxacin to ofloxacine with p= 0,002, but there were no significant differences between cyprofloxacinto polymyxin-neomycin with p=0,687, polymyxin-neomycin to ofloxacin p=0.057 and ofloxacin tochloramphenicol p=0,109.   There were significant differences in antibiotic ear dropssensitivity to Pseudomonas aeruginosa in patients with active benign type of CSOM. Cyprofloxacin andpolymyxin-neomycin were more sensitive than ofloxacin and chloramphenicol. Keywords: Pseudomonas aeruginosa, active benign type of chronic suppurative otitis media, antibioticear drops.  Abstrak :  Latar belakang: Otitis media supuratif kronik (OMSK) merupakan penyakit infeksi kronik telinga tengah yang sering dijumpai di klinik THT. Penyebab tersering OMSK adalah bakteri Pseudomonasaeruginosa. Pseudomonas aeruginosa mempunyai kemampuan untuk membentuk biofilm yangmelindunginya dari penetrasi antibiotik sehingga menimbulkan resistensi terhadap antibiotik dan sulituntuk eradikasinya. Tujuan: Untuk mengetahui perbandingan tingkat sensitivitas kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin terhadap isolat Pseudomonas aeruginosa padapasien OMSK benigna aktif di klinik THT RSMS. Metode: Metode yang digunakan adalah crosssectional terhadap 29 pasien OMSK di klinik THT RSMS periode bulan Agustus 2010 - Desember2010. Pengambilan sampel dilakukan dengan swab telinga. Uji sensitivitas terhadap kloramfenikol,polimiksin-neomisin, ciprofloksasin dan ofloksasin dilakukan dengan metode cakram secara difusi.Analisis yang digunakan dalam penelitian ini adalah Cochran dan analisis post hoc. Hasil: Didapatkansensitivitas kloramfenikol sebesar 38,70%, polimiksin-neomisin sebesar 83,87%, ciprofloksasin sebesar90,32% dan ofloksasin sebesar 58,06% dengan p=0,01 (P<0,05), yang menunjukkan adanya perbedaansensitivitas yang bermakna antara kloramfenikol, polimiksin-neomisin, ciprofloksasin dan ofloksasinterhadap Pseudomonas aeruginosa. Analisis post hoc menggunakan Mc Nemar menunjukkan bahwaterdapat perbedaan sensitivitas yang bermakna antara tetes telinga polimiksin-neomisin terhadapkloramfenikol, dan ciprofloksasin terhadap kloramfenikol p=0,000 (p<0,05), serta terdapat perbedaanyang bermakna antara tetes telinga ciprofloksasin terhadap ofloksasin, p=0,002, tetapi tidak terdapatperbedaan yang bermakna antara ciprofloksasin terhadap polimiksin-neomisin, p=0,687, polimiksinneomisinterhadap ofloksasin p=0,057, dan kloramfenikol terhadap ofloksasin p=0,109. Kesimpulan:Terdapat perbedaan sensitivitas yang bermakna tetes telinga antibiotik terhadap Pseudomonas aeruginosa pada pasien OMSK benigna aktif. Ciprofloksasin dan polimiksin-neomisin tetes telinga mempunyai sensitivitas yang lebih baik dibanding ofloksasin dan kloramfenikol. Kata kunci: Pseudomonas aeruginosa, otitis media supuratif kronik, tetes telinga antibiotik 

scholarly journals Coenzyme q10 is potentially usedto improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area

2018 ◽  
Vol 47 ◽  
pp. 07006
Author(s):  
Saryono Saryono ◽  
Hesti Devinta ◽  
Abdul Haris Budi Widodo ◽  
Arif Imam Hidayat
Keyword(s):  
Lipid Profile ◽  
Coenzyme Q10 ◽  
Coastal Area ◽  
Positive Control ◽  
Atherogenic Index ◽  
Control Group ◽  
Treatment Groups ◽  
Significant Difference ◽  
Pap Method ◽  
Post Hoc

Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high. The use of coenzyme Q10 to treat this disease has never been investigated yet. Therefore, this study aimedto analyze the effect of coenzyme Q10 on the lipid profile of diabetic hypercholesterolemia-induced periodontitis.Twenty four rats were randomized into 6 groups (G1-G6). The groups (G1-G3) are healthy, negative and positive control group respectively. The treatment groups (G4-G6) are diabetic hypercholesterolemia-induced rats given coenzyme q10 dose of 13,5; 27 and 54 mg/kg respectively. Rats were induced by periodontitis, hypercholesterolemia and diabetes mellitus. Coenzyme Q10 was administered orally using 2 mL gastric tube once a day for 14 days. Lipid profile including triglycerides, HDL, and atherogenic index (IA) was measured enzymatically by the CHOD-PAP method. Data were analyzed by one-way ANOVA test and followed by the Least Significant Difference (LSD) post hoc test.Coenzyme Q10 with a dose of 54 mg/kgis effective in lowering triglyceride, and atherogenic index and increasing HDL level in diabetic hyperlipidemia-induced periodontitis rats model. This research supports the potential effects of coenzyme Q10 supplementation to improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area.

scholarly journals PENGARUH FASE BULAN TERHADAP WAKTU TEBAR PANCING DAN LAJU TANGKAP MADIDIHANG (Thunnus albacares Bonnaterre, 1788) PADA ARMADA RAWAI TUNA

2017 ◽  
Vol 22 (4) ◽  
pp. 207
Author(s):  
Irwan Jatmiko ◽  
Bram Setyadji ◽  
Arief Wujdi
Keyword(s):  
Full Moon ◽  
Yellowfin Tuna ◽  
Catch Rate ◽  
Lunar Phase ◽  
Anova Analysis ◽  
Tukey Test ◽  
Significant Difference ◽  
New Moon ◽  
One Way Anova ◽  
Tuna Longline

Madidihang/yellowfin tuna merupakan salah satu jenis ikan tuna ekonomis penting bagi industri perikanan di Indonesia dengan kontribusi hasil tangkapan yang terbanyak. Penelitian ini bertujuan untuk mengetahui pengaruh fase bulan terhadap waktu mulai tebar pancing dan laju tangkap madidihang pada armada rawai tuna. Pengumpulan data dilakukan oleh pemantau ilmiah pada armada rawai tuna yang sebagian besar berbasis di Pelabuhan Benoa, Bali mulai Agustus 2005 hingga Juni 2014. Daerah penangkapan ikan dari armada rawai tuna yang diambil datanya berada di lokasi (lintang dan bujur) 9°-16° LS hingga 109°-120° BT. Analisis anova satu arah dan tes Tukey dilakukan untuk mengetahui pengaruh fase bulan terhadap waktu mulai tebar pancing dan laju tangkap madidihang. Total sebanyak 60 trip dan 1.467 hari operasi penangkapan armada rawai tuna dilakukan dalam penelitian ini. Analisis statistik anova satu arah menunjukkan bahwa terdapat pengaruh yang nyata pada fase bulan terhadap waktu mulai tebar pancing (p<0,05). Selanjutnya, tes Tukey menunjukkan bahwa waktu mulai tebar pancing pada saat bulan purnama dimulai pada pukul 9:00 pagi hari. Waktu ini lebih lambat sekitar 2 jam dari pada waktu mulai tebar pancing pada ketiga fase bulan lainnya (perbani awal, perbani akhir dan bulan baru) yang dilakukan sekitar pukul 7:00 pagi hari. Analisis statistik anova satu arah juga menunjukkan terdapat perbedaan yang nyata antar fase bulan terhadap laju tangkap madidihang (p<0,05). Selanjutnya, tes Tukey menunjukkan bahwa laju tangkap pada saat bulan baru dan perbani awal sebesar 0,13 ekor/100 mata pancing atau lebih besar dibandingkan nilai laju tangkap pada saat purnama dan perbani akhir yang hanya sebesar 0,09 ekor/100 mata pancing. Yellowfin tuna is one of the most economically important species for fisheries industry in Indonesia. The objectives of this study are to investigate the effect of lunar phase to the set time start and catch rate of yellowfin tuna on tuna longline vessels. Data collected by scientific observer on tuna longline vessels mainly based in Benoa Port, Bali from August 2005 to June 2014. Fishing ground of sampled longline tuna located from 9°-16° S to 109°-120° E. One-way anova analysis and Tukey test conducted to examine the effect of lunar phase to the set time start and catch rate of yellowfin tuna. A total of 60 trips and 1,467 fishing days of longline tuna fishing vessels operation have been sampled for in this study. One-way anova analysis showed that there was a significant difference of lunar phase to the set time start (p<0.05). Furthermore, Tukey test showed that the starting time for setting during the full moon begins at 9:00 am. Its time was around 2 hours slower than the start of setting of the other three moon phase (first quarter, last quarter and new moon) which start around 7:00 am. One-way anova analysis also showed that there was a significant difference of lunar phase to catch rate of yellowfin tuna (p<0.05). Furthermore, Tukey test confirmed that hook rate on new moon and first quarter was 0.13/100 hooks or 0.4 bigger than hook rate on full moon and last quarter with only 0.09/100 hooks.

scholarly journals PENGARUH GELATIN IKAN PATIN (PANGASIUS DJAMBAL) TERHADAP JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI TIKUS PUTIH (RATTUS NORVEGICUS)

2019 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Fredy Mardiyantoro ◽  
Fidya Fidya ◽  
Dena Savira Andriani
Keyword(s):  
Rattus Norvegicus ◽  
Tooth Extraction ◽  
Control Group ◽  
Fish Gelatin ◽  
Tukey Test ◽  
White Rats ◽  
Significant Difference ◽  
Post Hoc ◽  
Hematoxylin Eosin ◽  
Test Result

Background: Gelatin has been used as a hemostatic agent to stop bleeding and it can be absorbed by human body within 6 hours. The patin fish (Pangasius djambal) gelatin has a high amount of amino acid, especially glutamine which has an important role in increasing the proliferation of fibroblast in wounds. The purpose of this study was to determine the effect of patin fish gelatin to the number of fibroblast in wound after tooth extraction.Method: Rat’s tooth extraction is done on the lower left incisive tooth. Thirty white rats were divided into two groups randomly with 3 time series. Control group was the rats without given of patin fish gelatin and treatment group was the rats given 1cc of patin fish gelatin with pipette. Socket taken for histologically processed by Hematoxylin Eosin staining.Result: It showed there were significant differences in the number of fibroblasts between groups. The Post Hoc Tukey test result showed there was a significant difference between the control group and the treatment group.Conclusion: Patin fish gelatin has effect increasing the number of fibroblast inwound after white rat’s (Rattus norvegicus) tooth extraction

Aktivitas Pertumbuhan Rambut Hair Tonic Ekstrak Daun Bandotan (Ageratum conyzoides L.) Pada Kelinci Jantan (Oryctolagus Cuniculus)

2021 ◽  
Vol 1 ◽  
pp. 1194-1204
Author(s):  
Khofifah Fitriani ◽  
S Slamet ◽  
Dwi Bagus Pambudi ◽  
Urmatul Waznah
Keyword(s):  
Hair Growth ◽  
Oryctolagus Cuniculus ◽  
Ethanol Extract ◽  
Positive Control ◽  
Hair Length ◽  
Ageratum Conyzoides ◽  
Significant Difference ◽  
Growth Activity ◽  
Hair Care ◽  
One Way Anova

AbstractHair loss is a disorder or disorder of hair apart from the scalp or body skin so that it interferes with various biological functions of hair on the body. Types of hair care cosmetic that is effective in dealing with hair loss are hair tonic. Hair tonic is a preparation for the treatment of the scalp and hair. Bandotan (Ageratum conyzoides L.) is used by the public as medicine and hair care. The purpose of this study was to determine the formulation of hair tonic preparations from the ethanol extract of bandotan leaves according to the requirements and hair growth activity of local male rabbits. The extraction method used the maceration method with 96% ethanol and applied hair tonic extract of bandotan leaves on the skin of local male rabbits (Oryctolagus cuniculus) which were treated as blanks without smearing, positive control (Natur), negative control hair tonic base, concentration bandotan leaf extract. (5%, 10%, 15% and 20%) for 21 days. The data obtained in the form of hair length, and hair weight. Analysis of the data obtained for hair growth activity was seen from the results of the ANOVA test and continued with the BNT test (Least Significance Different). The results of the research for evaluating hair tonic preparations included organoleptic tests, pH tests, viscosity tests, specific gravity tests, and cycling tests. Hair tonic ethanol extract of bandotan leaves has hair growth activity. Hair tonic ethanol extract of bandotan leaves with a concentration of 20% had the highest hair length and hair weight. From the results of one way ANOVA, a significant value was obtained 0.000 < 0.005, so it was concluded that there was a significant difference between treatments, and continued with the BNT test (Least Significance Different) positive control was not significantly different from hair tonic concentration of 20%.Keywords: Bandotan leaves, Hair tonic, Hair growth AbstrakKerontokan rambut adalah suatu gangguan atau kelainan rambut terlepas dari kulit kepala atau kulit tubuh sehingga mengganggu berbagai fungsi biologis rambut terhadap tubuh. Jenis kosmetik perawatan rambut yang efektif mengatasi rambut rontok adalah hair tonic. Hair tonic adalah sediaan untuk perawatan kulit kepala dan rambut. Bandotan (Ageratum conyzoides L.) digunakan oleh masyarakat sebagai obat dan perawatan rambut. Tujuan dari penelitian ini mengetahui formulasi sediaan hair tonic dari ekstrak etanol daun bandotan yang sesuai dengan persyaratan dan aktivitas pertumbuhan rambut pada kelinci jantan lokal. Metode ekstraksi menggunakan metode maserasi dengan etanol 96% dan dilakukan pengolesan hair tonic ekstrak daun bandotan pada kulit kelinci jantan lokal (Oryctolagus cuniculus) yang diberikan perlakuan sebagai blanko tanpa pengolesan, kontrol positif (Natur), kontrol negatif basis hair tonic, ekstrak daun bandotan konsentrasi (5%,10%,15% dan 20%) selama 21 hari. Data yang diperoleh berupa panjang rambut, dan bobot rambut. Analisa data yang diperoleh untuk aktivitas pertumbuhan rambut dilihat dari hasil uji ANOVA dan dilanjutkan dengan uji BNT (Beda Nyata Terkecil). Hasil penelitian untuk evaluasi sediaan hair tonic antara lain uji organoleptis, uji pH, uji viskositas, uji bobot jenis, dan uji cycling test. Hair tonic ekstrak etanol daun bandotan memiliki aktivitas pertumbuhan rambut. Hair tonic ekstrak etanol daun bandotan dengan konsentrasi 20% memiliki panjang rambut dan bobot rambut tertinggi. Dari hasil one way ANOVA didapatkan nilai signifikan 0,000 < 0,005 sehingga disimpulkan adanya perbedaan signifikan antar perlakuan, dan dilanjutkan uji BNT (Beda Nyata Terkecil) didapatkan kontrol positif tidak berbeda nyata dengan hair tonic konsentrasi 20%.Kata kunci : Daun bandotan; Hair tonic; Pertumbuhan rambut

scholarly journals The influence of different screw tightening forces on the vertical misfit of implant-supported frameworks

2005 ◽  
Vol 13 (2) ◽  
pp. 120-125 ◽  
Author(s):  
Diego Klee de Vasconcellos ◽  
Marco Antonio Bottino ◽  
Renato Sussumu Nishioka ◽  
Luiz Felipe Valandro ◽  
Elza Maria Valadares da Costa
Keyword(s):  
Repeated Measures ◽  
In Vitro Study ◽  
Pairwise Comparisons ◽  
Tukey Test ◽  
Nickel Chromium ◽  
Marginal Discrepancy ◽  
The Mean ◽  
Post Hoc ◽  
One Way Anova

OBJECTIVES: The present in vitro study was designed to compare the differences in the vertical misfit of implant-supported frameworks using three different forces for tightening the bridge locking screws: fastening by hand until first resistance, and using torque drivers with 10 and 20Ncm. METHODS: The investigation was conducted based on the results given by 9 six-unit nickel-chromium (2 abutments/ 4 pontics) screw-retained implant-supported frameworks. The structures were exposed to simulated porcelain firings. The marginal misfit measurements were made using a traveling measuring microscope at selected screw tightening forces: fastening by hand until first resistance, and using torque drivers with 10 and 20Ncm. The results were submitted to one-way ANOVA with repeated measures on one factor, and post hoc pairwise comparisons using Tukey test (5%). RESULTS: The mean marginal misfit of the frameworks, fastening the screws by hand until first resistance, was 41.56µm (SD±12.45µm). The use of torque driver devices caused a significant reduction in marginal opening (p<0.05). With the lowest torque available (10Ncm), the mean marginal discrepancy at the abutment-framework interface was reduced an average of 52% to a mean marginal opening of 19.71µm (SD±2.97µm). After the use of the 20Ncm torque driver, the mean marginal discrepancy of the frameworks was reduced an average of 69% to a mean marginal opening of 12.82µm (SD±4.0µm). Comparing the use of torque drivers with 10 and 20 Ncm torque, the means are not significantly different from one another. CONCLUSION: The seating force has an important effect on the vertical misfit measurements, once it may considerably narrow the vertical misfit gaps at the abutment-framework interface, thus leading to a misjudgment of the real marginal situation.

scholarly journals Evaluation of Systemic Antioxidant Level and Oxidative Stress In Relation to Lifestyle and Disease Progression in Asthmatic Patients/ Evaluacija nivoa antioksidanasa i oksidativnog stresa u sistemu u odnosu na životni stil i progresiju bolesti kod obolelih od astme

2016 ◽  
Vol 35 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Abhay Singh Yadav ◽  
Manisha Saini
Keyword(s):  
Oxidative Stress ◽  
Catalase Activity ◽  
Healthy Individuals ◽  
Asthmatic Patients ◽  
Reducing Ability ◽  
Significant Difference ◽  
Severity Of The Disease ◽  
Student’S T ◽  
Plasma Antioxidant ◽  
Post Hoc

SummaryAsthma is a chronic disorder of the airways. Oxidative stress is an important part of asthma pathogenesis. It plays a crucial role in exacerbating the disease, as well as an important consequence of airways inflammation.Aim: The present study was undertaken to investigate the lipid peroxidation and catalase activity in serum and antioxidant level in plasma of asthmatic patients and their association with lifestyle and severity of the disease.Methods: A total of 210 subjects, 120 asthmatics and 90 healthy controls matched in respect to age, sex, lifestyle and socioeconomic status, were chosen randomly for the present study. The samples were analyzed for MDA concentration and catalase activity in serum and ferric reducing ability of plasma (FRAP). Statistical analysis was done using unpaired Student’s t-test, ANOVA with Duncan post hoc test and Pearson coefficient of correlation.Results: The serum MDA was found to be significantly higher in the asthmatics as compared to healthy individuals (p<0.01) while catalase activity in serum and antioxidant level of the plasma were markedly lower in the asthmatics as compared to healthy individuals (p<0.01). A significant difference was observed in serum MDA, catalase activity and plasma antioxidant level among the patients in relation to the severity of disease. There was a marked increase in the serum MDA in the patients with longer duration of the disease (p<0.05).Conclusion: The oxidant-antioxidant imbalance occurs in asthma leading to oxidative stress and is an important part of the asthma pathogenesis.

In Vitro Evaluation of Microleakage and Microhardness of Ethanolic Extracts of Propolis in Different Proportions Added to Glass Ionomer Cement

2016 ◽  
Vol 40 (2) ◽  
pp. 136-140 ◽  
Author(s):  
Mustafa Altunsoy ◽  
Mehmet Tanrıver ◽  
Uğur Türkan ◽  
Mehmet Emin Uslu ◽  
Sibel Silici
Keyword(s):  
Glass Ionomer Cement ◽  
Antibacterial Properties ◽  
Dental Practice ◽  
Glass Ionomer ◽  
Tukey Test ◽  
Ethanolic Extracts ◽  
Post Hoc ◽  
One Way Anova ◽  
Ionomer Cement

Objective: To evaluate the effect of ethanolic extracts of propolis (EEP) addition in different proportions to glass ionomer cement (GIC) on microleakage and microhardness of GIC. Study design: The cement was divided into four groups: one using the original composition and three with 10%, 25%, and 50% EEP added to the liquid and then manipulated. For microleakage assessment, sixty primary molars were randomly divided into four groups (n=15). Standard Class II cavities were prepared and then filled with EEP in different proportions added to GICs. Microleakage test was performed using a dye penetration method. The data were analyzed using one-way ANOVA and Mann - Whitney U tests (α = 0.05). Disc shaped specimens were prepared from the tested GIC to determine Vickers hardness (VHN). The data were analyzed using one-way ANOVA and post hoc Tukey test (α = 0.05). Results: There were no statistically significant differences between the groups in terms of microleakage (p &gt; 0.05). There were statistically significant differences between the VHN values of groups (p &lt; 0.05). Increasing addition of EEP to GIC statistically significantly increased VHN value of GIC (p &lt; 0.05). Conclusions: The addition of EEP to GIC increased the microhardness of the GIC and did not adversely affect the microleakage. Thus, it might be used during routine dental practice due to its antibacterial properties

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