Early preventive respiratory support in the complex treatment of patients with reduced motor activity on an outpatient and inpatient basis

2021 ◽  
Vol 6 (4) ◽  
pp. 2-10
Author(s):  
S. Fedorov ◽  
V. Sobolenkova ◽  
S. Fedorov ◽  
B. Nikanorov
Keyword(s):  
Physical Inactivity ◽  
Peak Pressure ◽  
Modern Medicine ◽  
Physical Activation ◽  
Complex Treatment ◽  
Urgent Problem ◽  
Muscular System ◽  
Energy Factors ◽  
Individual Use ◽  
Inpatient Basis

Physical inactivity is an urgent problem of modern medicine and society, characterized by a number of serious systemic disorders and claiming more than 5 million human lives every year. A timely increase in physical activity is obvious, however, there is a risk of developing tissue hypermetabolic syndrome associated with uncontrolled consumption of energy factors by the muscular system and possible damage to vital organs. In this regard, justified and proposed a system cardiorespiratory training, previous physical activation, by means of peak pressure in respiratory tract, through a portable device designed for individual use with a metered level of resistivity to reduce the risk of tissue hypermetabolism syndrome and increase in the future, the possibility of physical rehabilitation

scholarly journals The role of histamine H 1 receptors in the complex treatment of patients with allergic rhinitis

2019 ◽  
pp. 56-60
Author(s):  
S. V. Starostina ◽  
K. B. Volkova ◽  
N. V. Sergeeva
Keyword(s):  
Allergic Rhinitis ◽  
Modern Medicine ◽  
Complex Treatment ◽  
Actual Problem

In the article the actual problem of modern medicine – treatment of patients with allergic rhinitis (AR). Given the prevalence of AR are discussed classification issues, the etiology and pathogenesis of the disease. We consider the two-generation antihistamines in the treatment of patients with AR. Based on the data of several studies demonstrated benefits of antihistamines II generation, particularly levocetirizine.

scholarly journals CLINICAL EVALUATION OF TERPENE MEDICAMENT EFFECTIVENESS IN A COMPLEX TREATMENT OF CHRONIC GENERALIZED PARODONTITIS

2018 ◽  
Vol 2 (5) ◽  
pp. 133-136
Author(s):  
Марина Дударь ◽  
Marina Dudar ◽  
Владислав Молоков ◽  
Vladislav Molokov ◽  
Оксана Тирская ◽  
...  
Keyword(s):  
Antibacterial Agents ◽  
Clinical Observation ◽  
Modern Medicine ◽  
Complex Treatment ◽  
Curative Effect ◽  
Time Period ◽  
Wide Range ◽  
Complex Therapy ◽  
The Status ◽  
Resistant Strains

The article presents the comparative analysis of application of terpene-containing medicine Antiran (1:3 solution) and 0.06% chlorhexidine bigluconate solution in a complex therapy of patients with chronic generalized parodontitis. According to the curative effect, these drugs are comparable with antibacterial and antiseptic agents, but they act more gently and, as a rule, do not cause side effects. Currently, as a etiotropic therapy of periodontitis, a wide range of drugs affecting the parodontal pathogenic microflora, irrational use of antibacterial agents has acquired the status of a global problem of modern medicine, since it leads to the emergence of resistant strains of microorganisms that are poorly sensitive or resistant to treatment. The medicaments were used in ultrasonic scaling and for passive ultrasonic irrigation of periodontal pockets during curettage process. The results were evaluated according to the PMA, SBI, PI indexes, an extravazation time formation and periodontal pockets depth. The first total time period of clinical observation established that inflammation process was eliminated earlier when Antiran was used. Thus our study demonstrated and substantiated the successful experience of Antiran application in periodontal practice.

scholarly journals EXPERIENCE OF THE EFFECTIVENESS OF BACTERIOPHAGES IN THE PREVENTION OF CARIES IN CHILDREN

2020 ◽  
Vol 16 (2) ◽  
pp. 88-92
Author(s):  
Sofia Sysoeva ◽  
Evgeniy Ioshenko ◽  
Tatyana Stati ◽  
Elena Brusnitsyna ◽  
Taras Zakirov ◽  
...  
Keyword(s):  
Dental Caries ◽  
Oral Cavity ◽  
Complex Treatment ◽  
Special Equipment ◽  
Cariogenic Bacteria ◽  
Treatment And Prevention ◽  
Standard Scale ◽  
Individual Use ◽  
The Individual ◽  
Positive Results

Subject. Individualized etiotropic prevention of caries in children using bacteriophages. The goal is to study the peculiarities of the carioprophylactic effect of bacteriophages that are part of the drug "Fagodent." Methodology. The study involved 30 somatically safe children of 7―12 years of age with equal gender distribution and a decompensated caries course. The intensity of caries was determined by the formula KPU+CP. Patients with confirmed cariogenic bacteria dysbiosis were selected according to the CRT-bacteria test (Ivoclar company) at CFU/ml≥105. The method involves the collection of stimulated saliva, inoculation and incubation in a thermostat at a temperature of 37 °C for 2 days, the analysis of the number of colonies on a standard scale. The Green―Vermillion Hygiene Index (OHI-S) was also taken into account with an average of 0.9, children with high rates were excluded from the study. Results. After the course administration of the drug, the colonization rate of the oral cavity with cariogenic microorganisms decreases, which is reflected in the decrease in the Green―Vermillion (OHI-S) hygiene indices from 0.9±0.14 to 0.5±0.1 (p<0.05) and the test CRT-bacteria (Ivoclar Vivadent) CFU / ml from ≥105 to ≤105 (p<0.05). Upon further observation, within 3 months after the course of phagotherapy, the levels of contamination of the oral cavity with cariogenic microorganisms and hygiene were reliably kept low. Hygienic indicators also changed after the administration of the drug “Fagodent”: the Green― Vermillion hygiene index significantly decreased from 0.9±0.14 to 0.5±0.1 after 2 weeks and to 0.7±0.1 after 3 months. Findings. Clinical studies have proven the effectiveness of the drug "Fagodent" based on bacteriophages in the complex treatment and prevention of dental caries. The proposed scheme for the individual use of the drug under the supervision of a doctor does not require special equipment, is simple to implement and shows high positive results, which allows us to recommend it for the prevention of caries in children.

scholarly journals CLINICAL CASE OF SUCCESSFUL COMPLEX CERVICAL CANCER TREATMENT DURING PREGNANCY AND REVIEW OF LITERATURE

2020 ◽  
Vol 64 (1) ◽  
pp. 48-53
Author(s):  
S. Limareva ◽  
S. Khokhlova ◽  
O. Kravets ◽  
O. Shilkina
Keyword(s):  
Cervical Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Cesarean Section ◽  
Cancer Treatment ◽  
Clinical Case ◽  
Multidisciplinary Approach ◽  
Complex Treatment ◽  
Urgent Problem ◽  
Review Of Literature ◽  
The Postponement

Currently there is an increase in the incidence of cancer during pregnancy due to the postponement of procreation at a later age. The incidence of cervical cancer is 7.5-4.5 per 100,000 pregnancies and treatment remains an urgent problem and implies a multidisciplinary approach. The article describes the results of successful complex treatment for IB stage cervical cancer against the background of developing pregnancy with the inclusion of neoadjuvant chemotherapy followed by cesarean section, optimal surgery and brachytherapy.

scholarly journals Complications of pregnancy and childbirth in patients with diseases of the nervous system, their prevention and treatment

1995 ◽  
Vol XXVII (3-4) ◽  
pp. 54-56
Author(s):  
V. D. Ryzhkov
Keyword(s):  
Nervous System ◽  
Neurological Disorders ◽  
Modern Medicine ◽  
Urgent Problem ◽  
Pregnancy And Childbirth ◽  
Prevention And Treatment

An urgent problem of modern medicine is the development of measures for the prevention and treatment of neurological disorders before and during pregnancy. They are most often observed in patients with somatic and other pathologies.

scholarly journals INFLAMMATION ROLE IN FORMATION OF EARLY DISTURBANCES OF A FUNCTIONAL CONDITION OF A LIVER AT COMMUNITY — ACQUIRED PNEUMONIA (LITERATURE REVIEW)

2018 ◽  
Vol 8 (5) ◽  
pp. 361-365
Author(s):  
A. Yu. Gorbunov ◽  
H. S. Bobyleva ◽  
V. A. Zelenin ◽  
H. V. Suvorova
Keyword(s):  
Vascular Endothelium ◽  
Functional Condition ◽  
Hepatoprotective Activity ◽  
Modern Medicine ◽  
Community Acquired Pneumonia ◽  
Pharmacological Effects ◽  
Urgent Problem ◽  
Peroxide Oxidation ◽  
Therapeutic Approaches ◽  
High Incidence

The Community-acquired Pneumonia (CAP) is an urgent problem of modern medicine due to its high incidence, morbidity, the increasing resistance of a microflora to antibacterial therapy, a large number of complications and a high lethality. Now in a pathogenesis of pneumonia the leading value belongs to various changes of metabolism, including an induction of peroxide oxidation of lipids and formation of an oxidizing stress. The importance is attached to violations of a functional condition of a liver at pneumonia which pathogenetic mechanisms of damage are diverse, including with participation of a vascular endothelium. At the same time in realization of therapeutic approaches on a normalization of metabolism of cages of an organism the priority part is assigned to oxidation substrata. It is shown that the succinatecontaining medicines realize various pharmacological effects, providing in general cytoprotective action that allows to consider them as perspective the compositions having hepatoprotective activity which are necessary in complex therapy of the community-acquired Pneumonia (CAP).

scholarly journals Efficacy and Safety for Use Desloratadine in Children with Allergic Conditions (Literature Review, Own Research)

2021 ◽  
pp. 84-88
Author(s):  
Yurii Marushko ◽  
Olha Khomych
Keyword(s):  
Allergic Rhinitis ◽  
Literature Review ◽  
Medical Literature ◽  
Clinical Medicine ◽  
Personal Data ◽  
Allergic Diseases ◽  
Modern Medicine ◽  
Efficacy And Safety ◽  
Urgent Problem ◽  
Scientific Review

According to scientists, more than 20 thousand allergens are known and their number is constantly increasing. Therefore, children’s allergy remains one of the urgent problems of modern medicine, since allergic diseases in adults in most cases begin from childhood. The article summarizes our own data and presents a scientific review of the medical literature, which is devoted to the analysis of the problem of treatment of allergic diseases with desloratadine in children. Nowdays there is a significant prevalence of allergic conditions in children. We analyzed the effect of desloratadine on the course of allergic diseases in children. The analyzed literature review showed a high safety profile of the drug desloratadine. Also we presented the personal data of desloratadine therapy for seasonal allergic rhinitis in children. The literature data presented in the article and our own experience allow us to conclude that allergic conditions remain an urgent problem in clinical medicine, and the use of antihistamines, in particular desloratadine, increases the effectiveness of allergy therapy and accelerates the recovery and disappearance of symptoms.

scholarly journals Comparative Experimental Biomodelling of NSAID-induced Enterocolitis

Biomeditsina ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. 65-81
Author(s):  
R. A. Klesov ◽  
V. N. Karkischenko ◽  
O. I. Stepanova ◽  
O. V. Baranova
Keyword(s):  
Modern Medicine ◽  
Laboratory Animals ◽  
Intragastric Administration ◽  
Urgent Problem ◽  
Experimental Modelling ◽  
Laboratory Rats ◽  
Inflammatory Drugs ◽  
Ulcerative Lesions ◽  
First Time ◽  
Stomach Damage

Use of non-steroidal anti-inflammatory drugs (NSAIDs) is considered to be a factor in the development of gastrointestinal tract (GIT) diseases. Thus, enterocolitis is a frequent complication of NSAIDs. Experimental modelling of GIT diseases in laboratory animals, which describes the origin and mechanism of the corresponding disease in humans with maximal precision, is an urgent problem of modern medicine. This paper presents the results of comparative experimental biomodelling of NSAID-induced enterocolitis in laboratory rats. It was found that the intragastric administration of acetylsalicylic acid resulted mainly in stomach damage. The introduction of dexketoprofen — both orally and intramuscularly — causes erosive and ulcerative lesions of the stomach and intestines. The type of damage showed no correlation with the type of administration. For the first time, the results of enterocolitis biomodelling using dexketoprofen are presented.

scholarly journals Pharmacological correction of endothelial dysfunction using ademethionin and taurine

2019 ◽  
Vol 5 (2) ◽  
pp. 13-21 ◽  
Author(s):  
Taisiya A. Khadieva ◽  
Tatiana G. Pokrovskaya ◽  
Yulia Belousova
Keyword(s):  
Endothelial Dysfunction ◽  
Cross Section ◽  
Clinical Studies ◽  
Intraperitoneal Injection ◽  
Modern Medicine ◽  
Male Rats ◽  
Urgent Problem ◽  
Morphological Studies ◽  
Nos Inhibitor ◽  
Pharmacological Correction

Introduction: Рharmacological correction of endothelial dysfunction is a urgent problem of modern medicine. Materials and methods: Endothelial dysfunction was simulated in male rats using the e-NOS inhibitor L-NAME (25 mg/kg/day intraperitoneally, for 7 days). Simulation of ADMA-like preeclampsia was performed by intraperitoneal injection of L-NAME to females in the same doses for 7 days (14-20th days of pregnancy). These pathologies were corrected by administering ademethionine in dose 150 mg/kg and taurine at a dose of 260 mg/kg, as well as their combination at the same doses, intragastrically, through an atraumatic probe, once a day. Results: In the group with use of taurine at a dose of 260 mg/kg the coefficient of endothelial dysfunction decreased to the level of intact animals. Use of ademethionine at a dose of 150 mg/kg and taurine at a dose of 260 mg/kg combined resulted in the most pronounced endothelioprotective effect on the ADMA-like preeclampsia model. The coefficient of endothelial dysfunction decreased more than when using monotherapy of these drugs. Morphological studies of myocardiocytes showed that the combination of ademethionine at a dose of 150 mg/kg and taurine at a dose of 260 mg/kg prevented an increase in the cross-section of cardiomyocytes. Discussion: Possibly, ademethionine and taurine have an endothelioprotective effect because of their ability to decrease hyperhomocysteinemia. Conclusion: The investigated drugs showed pronounced endothelioprotective activity and can be recommended for further pre-clinical studies.

scholarly journals Evolution of upper urinary tract drainage method

2019 ◽  
Vol 12 (3) ◽  
pp. 199-202
Author(s):  
Oleg V Zolotuhin ◽  
Yuri Yurievich Madykin ◽  
Artur A Fedorov
Keyword(s):  
Urinary Tract ◽  
Literature Review ◽  
Upper Urinary Tract ◽  
Modern Medicine ◽  
Urgent Problem ◽  
Ureteral Catheter ◽  
Septic Complications ◽  
Percutaneous Puncture ◽  
Modern Methods ◽  
Urethral Stent

Despite the achievements of modern medicine, the method of drainage of the upper urinary tract with obstruction remains an urgent problem in urgent urological practice. The article presents a brief literature review of classical methods of upper urinary tract drainage, such as open nephrostomy and ureteral catheter installation. Special attention is paid to modern methods of drainage of the upper urinary tract. Percutaneous puncture nephrostomy today is one of the most frequently performed operations for the purpose of upper urinary tract drainage in urology, which is used both for medical and diagnostic purposes, which characterizes it as a fairly simple operation and safe for the patient, which has a number of significant drawbacks (wearing a urinal, possible purulent-septic complications, traumatization of the renal parenchyma). In contrast to percutaneous puncture nephrostomy, the urethral stent is devoid of the above disadvantages, however, it has no less significant disadvantages in use (migration, inlay, reflux).  

Sign in / Sign up

Export Citation Format

Share Document