scholarly journals Editorial

2021 ◽  
Vol 19 (2) ◽  
pp. 81
Author(s):  
Mario Bernardo-Filho
Keyword(s):  
Vitamin D ◽  
Negative Impact ◽  
Premature Mortality ◽  
Legal Aspects ◽  
The Body ◽  
Ultraviolet B ◽  
Whole Body ◽  
Sedentary Behaviors ◽  
Hematologic Cancer ◽  
The World

There is consistent and strong scientific evidenceabout the numerous health benefits related to thephysical activity (PA). Regular PA can improve physicalfitness and health and assist in the prevention of variousdiseases. In general, physically active adults are healthierand present higher physical performance in comparisonwith inactive adults worldwide. Among some desirablebehaviors, PA can be considered as part of a healthy lifestyleand can be categorized into occupational, sports,conditioning, household, or other activities involvingmovement of the body generated by skeletal muscleswith energy expenditure. Aligned with that, it is undeniablethe relevance of the physical inactivity as a riskfactor for premature mortality and for cardiovasculardisease and a variety of other chronic diseases, includingdiabetes mellitus, cancer (colon and breast), obesity,hypertension, bone and joint diseases (osteoporosis andosteoarthritis), and depression. Moreover, exercise inpatients with hematologic cancer, like leukemia, couldimprove immune function.Due to the relevance of the PA, it is important to stimulatebehaviors involving the physical practice. There areseveral factors that can influence these behaviors, suchas: personal (biological, health and psychological attributes),social (family, affiliation group, and work factors),and environmental (contexts for different forms of PAand policy factors that could determine availability ofrelevant settings and opportunities).The outbreak of the coronavirus disease 19 (COVID--19) has interfered in different factors of the PA behaviors.Depending of the severity of the COVID-19 inan individual, there are limitations to performed PA.Furthermore, aiming to contain the COVID-19 infectionsand to reduce interaction between infected andnon-infected individuals, strategies and restrictivepolicies have been suggested, such as quarantine, localconfinement, lockdown and isolation. It is clear that,while the individuals are confined at home the levelof PA, in general, decreases, due to the reduction of (i)daily activities outside, (ii) the participation in socialevents and, (iii) sometimes, of laboral activities. Thismay have a negative impact in general heath becauseit can contribute to sedentary behaviors. Besides theconfinement, it is important to consider other actionsto protect against the COVID-19 infection that is theuniversal use of masks.In addition to those facts, as an environmental factor,in confinement, the sunlight exposure is reduced.The relevance of the ultraviolet B radiation present insunlight to the active production of vitamin D in theorganisms is well known. This vitamin has a relevantrole to metabolic responses and protection againstdiseases, including cancer. Vitamin D deficiency hasbeen recognized as an undesirable global public healthproblem and it plays a wide role in health and in theprevention of several diseases, including the COVID-19.As the reduction of the muscle strength is observedin the individuals that had COVID-19, PA or exercisescould be important for their rehabilitation. There aredifferent modalities of exercises that could be also usedfor them, including the whole-body vibration exercisesto improve the muscular performance.Putting together, people in the world is living, or istrying to live, in conditions to maintain a minimal, butconvenient level of PA to have health to contercousethe bad situation of the COVID-19 up to a definitiveand confident vaccin be available to the human beings.The researchers are working hard to aid the worldpopulation to win this fight against the COVID-19 andthe sedentary behaviors.Naturally, COVID-19 and the sedentarism are problemsfor the world, but the continuous education aboutthe importance of PA, the studies about the effects ofmedications that can be used in the treatments of diseases,the control of use of drugs, as the pesticides, andthe discussion about the biological and legal aspects ofreprocessing of medical-hospital material are welcometo contribute to improve the health.

ELOQUENT ACTION: THE BODY AND MEANING IN EARLY COMMEDIA DELL'ARTE

2009 ◽  
Vol 50 (2) ◽  
pp. 251-315 ◽  
Author(s):  
Matthew Buckley
Keyword(s):  
Facial Expression ◽  
Human Nature ◽  
External Action ◽  
The Body ◽  
Whole Body ◽  
Commedia Dell'arte ◽  
General Terms ◽  
The World ◽  
The Many ◽  
Common Character

One of the things that strikes one most forcibly in surviving images of early commedia dell'arte is its enigmatic physicality, the manner in which its actors everywhere adopt postures and make gestures that seem not merely emphatic and exaggerated but almost hieroglyphic, full of some additional implication, laden with a figural and emblematic resonance that we sense but no longer see. In general terms, this quality is easily understood, as the body clearly served in commedia as a complex and polyvalent instrument of expression. Its gestures and movements were, as in all theatre, indexically linked to dramatic action, and they also served, as in much masked drama, as surrogates for the facial expression of affect, in that the movements and aspects of the whole body were enlisted to articulate the motions and mien of a veiled face and to overcome or play upon the sensation of estranged speech produced by the half-mask's bifurcation of the visage. Moreover, in a manner less familiar but illustrated well in Fig. 1, these movements and aspects also functioned as expressions in their own right, not articulating the affect or expression attendant upon immediate speech or situation or delineating the lines of external action but signaling the many impulses and various appetites of the world, the varied aspects of all persons and of the body itself, and invoking at times as their implicatory context human nature, common character, and identity rather than situation, attitude, or emotion.

scholarly journals Analisis Dampak Sosial Akibat Pabrik Kertas Di Desa Parmaksian Tobasa Menggunakan Paradigma Ekofeminis

2021 ◽  
Vol 19 (1) ◽  
pp. 53-70
Author(s):  
Ayu Indira Hasugian
Keyword(s):  
Social Impact ◽  
Negative Impact ◽  
Paper Industry ◽  
Paper Mill ◽  
Social Impacts ◽  
The Body ◽  
The Social ◽  
The World ◽  
The Impact

AbstrakDesa Siruar Parmaksian Tobasa di salah satu desa yang berada di daerah Toba mengalami perubahan sosial akibat dampak negatif berdirinya PT TPL. Dampak yang diberikan mengarah kepada kaum perempuan/ibu sehingga mengakibatkan aktivitas sehari-hari perempuan/ibu menjadi terkendala. Dampak ini terjadi di setiap harinya, sehingga akan sangat berdampak buruk bagi hubungan antara perempuan dan alam. Melihat kasus tersebut peneliti ingin melakukan penelitian terhadap kondisi  yang dialami kaum perempuan/ibu tersebut. Tujuan penelitian ini untuk menganalisa dampak sosial akibat pabrik kertas di Desa Siruar Parmaksian Tobasa kepada para perempuan dengan menggunakan paradigma Ekofeminis yang di tawarkan oleh McFague dan Warren, dan dikaji dalam bentuk studi kasus. Metode penelitian yang peneliti pakai adalah Metode Studi Kasus dari Teori E.P Gintings. Ada beberapa isu yang muncul dari kasus atau masalah ini, diantaranya : dampak sosial, dampak kerusakan alam terhadap kehidupan para perempuan, dan paradigma baru relasi perempuan dan alam atau rekonstruksi paradigma. Hal ini dilakukan untuk mengetahui Bagaimana dampak sosial akibat pabrik kertas terhadap masyarakat yang berada di lingkungan  Industri Kertas di Desa Siruar Parmaksian Tobasa yang mengarah kepada perempuan yang terdampak dan Bagaimana upaya-upaya yang dilakukan kaum perempuan/ibu di desa siruar untuk mempertahankan tanah/wilayahnya yang telah di rusak oleh perusahaan tersebut?. Hasil Analisis menunjukkan bahwa  paradigma Ekofeminis sudah menerapkan paradigma dengan istilah “Konstruksionisme”, yang disebut dengan istilah metafora dunia sebagai tubuh Allah, artinya dunia harus dipahami sebagai satu kesatuan organik, tubuh Tuhan dan bisa menanamkan sikap yang menghargai dunia.Kata Kunci: dampak sosial, paradigma ekofeminis AbstractThe village of Siruar Parm testimony Tobasa in a village in the Toba area experienced social changes due to the negative impact of the establishment of PT TPL. The impact that is given is directed at women / mothers so that it causes the daily activities of women / mothers to be constrained. This impact occurs every day, so it will have a very bad impact on the relationship between women and nature. Seeing this case, the researchers wanted to conduct research on the conditions experienced by these women / mothers. The purpose of this study is to analyze the social impacts of the paper mill in Siruar Parm testimony Tobasa on women using the Ecofemist paradigm offered by McFague and Warren, and study it in the form of a case study. The research method that researchers use is the Case Study Method of E.P Gintings Theory. There are several issues that arise from this case or problem, including: social impacts, the impact of natural destruction on women's lives, and a new paradigm of relations between women and nature or paradigm reconstruction. This is done to find out how the social impact of the paper mill on the community living in the Paper Industry in Siruar Parm testimony Tobasa Village which leads to affected women and how the efforts made by women / mothers in Siruar Village to defend their has been damaged by the company ?. The results of the analysis show that the Ecofemist paradigm has applied a paradigm with the term "Constructionism", which is called the metaphor of the world as the body of God, meaning that the world must be understood as an organic unit, the body of God and can instill an attitude of respect for the world. Keywords: social impact, eco-feminist paradigm

scholarly journals PENETAPAN KADAR KAFEIN PADA BUBUK TEH HITAM YANG BEREDAR DI PASAR DELI TUA MENGGUNAKAN SPEKTROFOTOMETRI UV

2020 ◽  
Vol 3 (1) ◽  
pp. 21-28
Author(s):  
DIAN IKA PERBINA MELIALA
Keyword(s):  
Side Effects ◽  
Sampling Method ◽  
Negative Impact ◽  
Black Tea ◽  
The Body ◽  
Test Results ◽  
Ultraviolet Spectrophotometry ◽  
The Public ◽  
Validation Test ◽  
The World

Tea is a drink that is very familiar in the world and is very common in everyday life. Tea is also the most consumed and favored beverage by the public after water. Besides being beneficial, tea also contains compounds that have a negative impact on the body, namely caffeine compounds. Caffeine is an alkaloid of the methylxanthine group which plays a role in increasing the work of psychomotor in the body, and side effects that can be caused are anxiety, irregular heartbeat, difficulty sleeping, tremors, diuresis and others. The purpose of this study was to determine the caffeine content in black tea powder circulating in the Old Deli market. This type of research is descriptive with a purposive sampling method. The analytical method used is qualitative with murexide and quantitative ultraviolet spectrophotometry with a wavelength of 267nm. The results of a qualitative analysis of all positive samples contained caffeine. The average quantitative yield of caffeine in brand A black tea powder was (4,82 ±0,0356)%, B brand black tea powder (4,89 ± 0,0173)% and C brand black tea powder (4,93 ± 0,0531)%. The validation test results obtained linearity r = 0,9984, LOD and LOQ is 0,8074 mcg/ml and 2,6914 mcg/ml ,% recovery = 100,07%, RSD = 0,33%. Based on the results of research conducted, it can be concluded that ultraviolet spectrophotometry can be used to determine caffeine levels in black tea powder.

6. From thought to action

2021 ◽  
pp. 89-103
Author(s):  
Jamie A. Davies
Keyword(s):  
Skeletal Muscle ◽  
Nervous System ◽  
Musculoskeletal System ◽  
Muscle Cells ◽  
Mechanical Force ◽  
The Body ◽  
Chemical Energy ◽  
Whole Body ◽  
The World ◽  
Ultimate Result

This chapter addresses muscles. The ultimate result of sensation and thought is usually some kind of action, be it moving the whole body; manipulating an object with the hand; or moving diaphragm, mouth, tongue, and voice-box to speak. All of these depend on muscles which, in their various forms, provide a nearly universal means for the nervous system to control the body and the world. Muscle cells are highly adapted for turning chemical energy into mechanical force. The chapter then looks at skeletal muscle and the musculoskeletal system. Some muscles are arranged circumferentially around a cavity. Two examples of this are the heart and the gut.

scholarly journals Vitamin D and Temporomandibular Disorders: What Do We Know So Far?

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1286
Author(s):  
Andreea Kui ◽  
Smaranda Buduru ◽  
Anca Labunet ◽  
Silvia Balhuc ◽  
Marius Negucioiu
Keyword(s):  
Vitamin D ◽  
Temporomandibular Disorders ◽  
Potential Role ◽  
Current Knowledge ◽  
Masticatory Muscles ◽  
The Body ◽  
Ultraviolet B ◽  
Pathological Conditions ◽  
Temporomandibular Joints

Background and aims. Vitamin D is synthesized in the skin with the aid of ultraviolet-B radiation, playing a variety of roles in the body. Temporomandibular disorders (TMDs) are a group of pathological conditions involving the temporomandibular joints as well as the masticatory muscles and othersurrounding tissues. In the present narrative review, we investigated the potential role of vitamin D in the etiology of temporomandibular disorders in order todetermine whether the current knowledge supports 25-hidroxyvitamin D (25-OHD) supplementation in temporomandibular disorders associated with insufficient or deficient levels of vitamin D. Methods. A literature research was performed in PubMed, Scopus, Science Direct, and Google Scholar databases, and a total of 10 articles were included for analysis. Results.Among the observational studies published to date, investigating the role for vitamin D in the etiology of TMDs, six of them suggest that there is a connection between the two aspects. In this context, patients suffering from TMD, with deficient levels of vitamin D (<30 ng/mL), are most likely to benefit from supplementation, whereas individuals with vitamin D level >50ng/mL probably have little benefit from supplementation.Conclusion.Vitamin D might be a safe, simple, and potentially beneficial way to prevent TMDs or to reduce pain; however, more randomized and placebo-controlled trials are required before any firm conclusions can be drawn.

scholarly journals Exploring Knowledge, Attitude and Practice (KAP) Towards Vitamin D among Arts and Commerce Students in Vistas Chennai

2021 ◽  
pp. 23-28
Author(s):  
M. Varaprasanna Rao ◽  
Mashhud Alam
Keyword(s):  
Vitamin D ◽  
Vitamin D3 ◽  
The Body ◽  
Ultraviolet B ◽  
Face Validity ◽  
Knowledge Domain ◽  
Cross Sectional ◽  
Attitude And Practice ◽  
Commerce Students ◽  
Knowledge Attitude And Practice

Introduction: Vitamin D is an essential nutrient and a group of fat-soluble pro-hormones with multiple functions in the body including bone health, regulation of serum calcium and phosphate levels, as well as roles in immune function, cell proliferation, differentiation, and apoptosis. The two major biologically inert precursors of vitamin D are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol). Vitamin D3 is also formed when the skin is exposed to solar ultraviolet B and then converted to pre-vitamin D3 (Sunshine Vitamin). The severe vitamin D deficiency in adults and children’s causes softening of bones, muscle weakness and fractures. Aim: The aim of the study is to explore knowledge, Attitude and Practice towards Vitamin D among Arts & Commerce students in Vels University Chennai. Methods and Materials: The study was a prospective cross-sectional, carried out in the department of arts and commerce students in VISTAS Chennai. The questionnaire then underwent a series of validation process that included content, face validity and exploratory part. Item response theory (IRT) analysis was utilized for the validation of the knowledge domain. Exploratory factor Analysis (EFA) used for attitude and practice validation. Institutional Ethical Committee (VISTAS-SPS/IEC/VI/2020/05) approval was obtained before conducting the study. Self-online questionnaires link was sent via mail after registration. The questionnaire was divided based on Knowledge, Attitude and Practice with 5 questions each. Completed questionnaires were reviewed, entered into a database (SPSS) and analysed using descriptive and inferential statistics. Results and Discussion: In our study, a total of 362 students were included where majority were males from first year commerce department around 18 to 19 years of age. Majority of the students had knowledge on vitamin D, attitude towards every day sun exposure and practice of using sun screens. Conclusion: Our study concluded that the students’ knowledge on vitamin D is good. There was an inconsistent practices towards managing its deficiency. Despite widespread, concern about vitamin D, still attitude and practice towards Vitamin D is yet to known for young generations.

scholarly journals The Essential Role of Vitamin D in the Biosynthesis of Endogenous Antimicrobial Peptides May Explain Why Deficiency Increases Mortality Risk in COVID-19 Infections

2020 ◽  
Author(s):  
Patrick J. McCullough ◽  
Jeffrey Amend ◽  
William P. McCullough ◽  
Steven J. Repas ◽  
Jeffrey B. Travers ◽  
...  
Keyword(s):  
Vitamin D ◽  
Antimicrobial Peptides ◽  
Vitamin D3 ◽  
Skin Pigmentation ◽  
Sun Exposure ◽  
Ultraviolet B ◽  
Whole Body ◽  
High Risk Population ◽  
Uvb Radiation ◽  
Vitamin D Receptors

Abstract: A primary action of vitamin D is regulation of gene transcription. Many cell types possess genes that make antimicrobial peptides (AMPS) (endogenous antibiotics), recently discovered to be regulated by vitamin D. Two examples are cathelicidin and beta defensins, both bioactive against many different bacteria, fungi, mycobacteria, parasites and viruses. The signal transduction pathway is triggered by sensing microorganisms via cell surface receptors, causing intracellular production of calcitriol (1,25(OH)2D) and vitamin D receptors, leading to upregulation of AMP production. Serum 25(OH)D concentrations required to sustain adequate AMP production to eradicate infections are unknown. Vitamin D3 is photosynthesized in skin in amounts ranging from 10,000 (250 mcg) to 25,000 (625 mcg) International Units (IU) from 7-dehydrocholesterol after whole-body exposure to one minimal erythemal dose (MED) of ultraviolet B (UVB) radiation, and is impacted by many factors including geographic localities, seasonal changes and skin pigmentation. We and others have reported extended daily oral dosing with these amounts of vitamin D3 safe. We routinely observe serum 25(OH)D concentrations below 20ng/ml on new admissions, which have been reported insufficient to sustain AMP production. In contrast serum 25(OH)D concentrations above 100ng/ml have been reported after serial UVB treatments for psoriasis. Little vitamin D naturally occurs in food, and insufficient sun exposure may be causing worldwide deficiency. We review evidence suggesting that higher daily intakes of vitamin D3 than the currently recommended 600 (15 mcg) IU/day may be necessary to sustain AMP production in the face of an overwhelming infection, particularly in non-Hispanic blacks, a high risk population suffering the worst outcomes from COVID-19. We propose that increased vitamin D supplementation could provide a safe and cost-effective way to protect all populations from infections, in particular those from pandemic COVID-19.

scholarly journals Characteristics of Serum Ratios of 1,25-Dihydroxyvitamin D to 25-Hydroxyvitamin D for Assessment of Bone Metabolism

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A272-A273
Author(s):  
Koichiro Yamamoto ◽  
Manami Fujita ◽  
Hiroyuki Honda ◽  
Yoshihisa Hanayama ◽  
Kazuki Tokumasu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Active Form ◽  
The Body ◽  
Ultraviolet B ◽  
Hydroxyvitamin D ◽  
Dihydroxyvitamin D ◽  
1,25 Dihydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Gender Specific

Abstract Vitamin D is obtained in the body by food intake or by production from 7-dehydrocholesterol by exposure of the skin to ultraviolet B radiation. It is first metabolized in the liver to 25-hydroxyvitamin D (25D), which is a major circulating metabolite. In the kidney, 25D is subsequently metabolized to the hormonally active form, 1,25-dihydroxyvitamin D (1,25D), via 1α-hydroxylase encoded by the CYP27B1 gene. 1,25D has a cellular effect through the vitamin D receptor, which leads to calcium absorption in the gut, bone metabolism, and parathyroid function. A recent study showed that a low vitamin D status is common worldwide and is associated with various diseases including kidney, heart, and liver failure, secondary hyperparathyroidism, osteomalacia, inflammatory bowel disease, granuloma-forming disorders (sarcoidosis and tuberculosis), and cancer. Vitamin D deficiency also increases the risks of falls, fractures, bone loss, sarcopenia, leading to worse outcomes of illness severity, morbidity, and mortality. The 1,25D/25D ratio is considered to be a useful tool for diagnosis of ocular sarcoidosis; however, its clinical utility and relevance to pathophysiology of evaluation of the ratio 1,25D/25D which indicates vitamin D activation have remained unknown. To clarify the clinical usefulness of markers for vitamin D activation, 87 patients in whom serum 25D and 1,25D level was measured were retrospectively reviewed in the present study. Data for 79 patients (33 males and 46 females) were analyzed after exclusion of 8 patients taking vitamin D. The median serum 1,25D/25D ratio was significantly lower in males than in females: 4.1 (IQR: 2.3–5.8) x 10−3 versus 6.8 (3.0–9.8) x 10−3. However, individual levels of 25D and 1,25D were not different in males and females. The major categories of main disorders were endocrine (30.6 %), inflammatory (18.5 %), and bone-related (16.7 %) disorders. The ratios of serum 1,25D/25D had significant negative correlations with femoral dual energy X-ray absorptiometry % young adult mean (DEXA %YAM) (R=-0.35) and lumbar DEXA %YAM (R=-0.32). Significant correlations were found between 1,25D/25D ratio and serum levels of inorganic phosphate (R=-0.34), intact parathyroid hormone (R=0.64) and alkaline phosphatase (R=0.46) in all patients. Of interest, the 1,25D/25D ratio had gender-specific characteristics: the ratio had a significant correlation with age in males (R=0.49), while it had a significant correlation with body mass index (BMI) in females (R=0.34). Collectively, the results revealed that the ratio of serum 1,25D/25D as a marker for activation of vitamin D had relevance to clinical parameters, especially bone turnover, with gender-specific features. It is suggested that the existence of a gender-specific difference of aging males and obese females regarding the activation of vitamin D that is functionally linked to bone metabolism.

scholarly journals The Survey of Sea Cucumber Fisheries on Qeshm Island Coasts (Persian Gulf)

2013 ◽  
Vol 15 (1) ◽  
pp. 127-136 ◽  
Author(s):  
Majid Afkhami ◽  
Maryam Ehsanpour ◽  
Amin Mokhleci ◽  
Kazem Darvish Bastami
Keyword(s):  
Human Health ◽  
Sea Cucumber ◽  
The Body ◽  
Silty Sand ◽  
Whole Body ◽  
Qeshm Island ◽  
Sea Cucumbers ◽  
Tropical Regions ◽  
Holothuria Scabra ◽  
The World

ABSTRACT Sea cucumbers are aquatic animals of wide variety, useful for human health. Sea cucumbers are among the aquatic creatures that have many important and useful properties known for human health. Increasing demand for beche-de-mer, along with steady price increases, has led to worldwide intensification of sea cucumber harvesting. The rearing of sea cucumbers with shrimps controls environmental pollution that results from over- enrichment in nutrients, built up on the pond bottom. These animals eat detritus and, together with devouring organic materials on the surface, not only do they clean the environment, but also they cause the fast growth of shrimps and themselves. Holothuria scabra is the main species for production of beche-de-mer and is exploited especially in the tropical regions of the world. The wall of the body used in the process of beche-de-mer production forms 56% of the whole body. Holothuria scabra (sandfish) is an aspidochirote holothurian widely distributed in coastal regions throughout the Indo-Pacific region. H. scabra is often found on inner reef flats and near estuaries, half-buried in silty sand during the day and emerging at night to feed. In this study, based on information from local fishermen on Qeshm Island, we provide some data about the fishing methods, processing and distribution on the Qeshm Island coastline. Comparative study of fishing status with another part of the world determined that the status of sea cucumber stocks in Qeshm Island is sustainable. For prevention of overexploitation of the sandy sea cucumber, prohibition on capturing should continue. In this study, seven exploited sites are recognized, the target size for fishermen was more than 20 cm and sandy cucumber was the target species in Qeshm Island. In this area, the fishing operation was only carried out by scuba diving and was done only by men; although in another countries women have an important role in sea cucumber fishing activities. Among the coasts around Qeshm Island, it is found at Hmoon, Tolla, Kovei, Ramchah, Messen and Hengam. A maximum length of 35 cm and maximum weight of 1,080 g was recorded.

scholarly journals Types and devices for smoking and their harmful effects on the human body

2021 ◽  
pp. 81-90
Author(s):  
I.S. Lisetska ◽  
Keyword(s):  
Smoking Cessation ◽  
Young People ◽  
Human Health ◽  
Human Body ◽  
Negative Impact ◽  
Electronic Cigarettes ◽  
Smoking Habit ◽  
The Body ◽  
Chewing Tobacco ◽  
The World

The literature review focuses on the prevalence of smoking among the population, the types of smoking devices and their negative impact on public health. The article presents the composition of traditional cigarettes and alternative types of smoking, analyzes the data of smoking statistics in the world. The smoking habit has been known since 2000 BC, when American Indians inhaled the smoke from burning the leaves of the plant Nicotiana tabacum, in the 20th century became an epidemic and killed more than 100 million people, and according to forecasts in the XXI century, this figure may grow in order. It is alarming that in recent decades, in addition to traditional cigarettes, alternative types of smoking have become popular, especially among adolescents and young people, namely electronic cigarettes (E-cigarettes, vapes), tobacco heating devices (IQOS), and sometimes products. With low tobacco content (snuff, chewing tobacco, etc.). In addition, hookah remains fashionable and sometimes prestigious among young people, which also has a detrimental effect on the human body. Smoking both traditional cigarettes and alternative types is one of the important medical and social problems both in Ukraine and around the world, as it is widespread and available. Smoking is a risk factor for human health and, as a result, an increase in nicotine-related mortality. At the same time, smoking is the only cause of illness and death that can be eliminated. Today, smoking is considered not as a bad habit, but as a chronic disease, prone to recurrence, even long after smoking cessation. There are no safe types of smoking, active and passive smoking are equally harmful to the body, which undermines human health and threatens his life. Smoking is especially dangerous for adolescents and young adults. The fight against smoking remains a key factor in the recovery of the nation. Smoking cessation is not only a matter of prevention, it should be considered as one of the appointments for the patient in the treatment of any disease and rehabilitation, because without it there will be no success in treatment and health. No conflict of interest was declared by the author. Key words: smoking, cigarettes, nicotine, electronic cigarettes, IQOS, hookah, snus.

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