Risk of Pesticide Exposure on Impaired Level of Intelligence (IQ) of Children

The shallot cropping pattern applied by farmers in the village of Pasir Demak is very likely to cause pollution. Pesticide contamination in pregnant women in the first trimester (3 months) can result in fetal death, low birth weight, and impaired intelligence (IQ). Preliminary research conducted in 2016 found that elementary schooler who came from Pasir Village, Demak had low learning achievement. It was an observational study with a cross-sectional approach; the respondents were Elementary Schooler grades 4, 5, and 6 (107 people) and the mothers of the students (107 people). Thus, the total respondents were 214 people. The IQ assessment instrument used the SPM and CPM instruments. The level of pesticide poisoning from the mother was to measure blood Cholin Esterase levels using a tintometer, the data were then statistically analyzed using Chi Square and Odd Ratio for risk factors. There were significant differences on the level of intelligence of children including the planting system p=0.002; room area p=0.047; ventilation area p=0.041; type of pesticide p=0.001; spraying before harvest p=0.007; spraying after harvest p=0.008; storage place for crop yields p=0.039, while the variables that did not show significant difference were the playing environment p=0.848; gestational age p=0.190; contact to pesticides p=0.105 and age p=0.418. Pesticide contamination in pregnant women in the 1st trimester which the time to process formation and development of the brain in the Temporal lobe and Frontal lobe will experience impaired learning and memory (IQ). Keywords : Elementary schooler; Pesticide exposure; Level of intelligence.

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Serum Magnesium Levels among Pregnant Women with and without Complications: A Cross-sectional Study

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2020/44402.13992 ◽

2020 ◽

Author(s):

Santhini Gopalakrishnan Sethulekshmi ◽

S Sumathy ◽

Banani Dutta

Keyword(s):

Pregnant Women ◽

Magnesium Deficiency ◽

Serum Magnesium ◽

First Trimester ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Significant Difference ◽

History Of ◽

Student’S T

Introduction: Pregnancy is a period that is characterised by remarkable physiological changes which are needed to support the growing fetus. Micronutrients play a crucial role in the maintenance of pregnancy. Among the micronutrients, magnesium has got ample amount of clinical relevance to pregnancy. Magnesium deficiency has been associated with reproductive risk during pregnancy such as anaemia, pre-eclampsia, eclampsia, fetal growth retardation, preterm labour, low intrauterine growth rate and leg cramps. Aim: To find out whether there was significant difference in the magnesium levels among pregnant women with and without pregnancy related complications and also to find out whether the magnesium levels differed significantly among the three trimesters. Materials and Methods: This was a cross-sectional study done among 240 pregnant patients from different trimesters attending the Obstetrics and Gynaecology Outpatient Department. Out of them 164 women had complications like pre-eclampsia, Gestational Diabetes Mellitus, leg cramps and history of abortions. Demographic details were obtained from all the women. BMI was calculated for each subject using the formula BMI=weight(kg)/height(m2). Haemoglobin was assessed in all samples using cyanmethaemoglobin method. Magnesium levels were analysed in the all samples using automated analyser in the Biochemistry laboratory. Student’s t-test was used to compare the levels of magnesium among the groups with and without complications. ANOVA test was used to compare the three trimesters. Results: The pregnant women were divided into three groups based on the different trimesters in which the samples were taken. Magnesium levels among the women in the first trimester were (2.96±0.83) second trimester (2.99±1.48) and third trimester (3.05±1.48) respectively. Women with previous abortions were found to have less magnesium levels (2.71) compared to women without a history of abortion (3.11) and value was found to be statistically significant (p<0.007) and magnesium levels among vegetarians (2.45) were lower than non vegetarians (3.08) and it was found to be statistical significant (p<0.013). There was no significant difference in the magnesium levels among pregnant women with complications and those without complications. Conclusion: The study shows the importance of maintaining the magnesium levels among pregnant women. There was no difference in the magnesium levels among the three trimesters. Study also points out the influence of parity, diet and occupation of pregnant women on the levels of magnesium.

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Hematological Parameters in Pregnant Women with Special Reference to Iron

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i58b34182 ◽

2021 ◽

pp. 137-142

Author(s):

Shubhranshu Shekhar

Keyword(s):

Pregnant Women ◽

Hematological Parameters ◽

First Trimester ◽

Control Group ◽

Mean Corpuscular Hemoglobin ◽

Corpuscular Hemoglobin ◽

Cross Sectional ◽

Hematological Indices ◽

Group I ◽

Significant Difference

Several biological factors, particularly haematological, are physiologically altered during normal pregnancy. Biologists and doctors who are aware of these changes in the maternal body can screen for potential abnormalities. The aim of this research is to find healthy pregnant women's reference values. This was a cross-sectional research of pregnant women who attended an antenatal clinic at Sree Balaji Medical College, with anaemic and non-anemic pregnant women. Pregnant women were categorized into three groups -Group I - First Trimester (50 cases); Group II - Second Trimester (50 cases) and Group III - Third Trimester (72 cases) while non pregnant women formed the fourth group (30 cases). A statistically significant difference between the pregnant women and control group was noted (p < 0.05) for all the hematological parameters: red blood cells, hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocytes, neutrophils, basophils, eosinophils, lymphocytes, monocytes, platelets and mean platelet volume. The present study provides additional baseline data for basic hematological parameters in healthy pregnant women and concluded that pregnancy in women has the tendency to alter some hematological indices.

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Anxiety and depression in pregnant women amid COVID-19 pandemic

Asian Journal of Medical Sciences ◽

10.3126/ajms.v12i9.37229 ◽

2021 ◽

Vol 12 (9) ◽

pp. 26-30

Author(s):

Pravin Shrestha ◽

Vibha Mahato ◽

Anil Subedi ◽

Shipra Shrestha

Keyword(s):

Pregnant Women ◽

First Trimester ◽

Cross Sectional Study ◽

Anxiety And Depression ◽

P Value ◽

Second Trimester ◽

Cross Sectional ◽

Significant Difference ◽

Prevalence Of Depression ◽

Hospital Patients

Background: COVID-19 has become a global pandemic. It has affected the psychological condition of pregnant women. Aims and Objective: This study aims to assess prevalence of depression and anxiety in pregnancy during COVID-19 pandemic. Materials and Methods: The current study was an observational, cross sectional study conducted in the Department of Obstetrics and Gynecology, Manipal Teaching Hospital. Patients were assessed using Nepali version of Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) for anxiety and depression respectively. Result: There were total of 115 patients in this study. The prevalence of anxiety according to BAI was 39.1%. The prevalence of depression according to BDI was 19%. There was a statistically significant difference in rate of anxiety according to maternal age (p value 0.028). Anxiety was higher in women less than 20 years of age. Anxiety symptoms were more prevalent i.e., 44.6% in third trimester followed by 31.4% in second trimester and 29.4% in first trimester. Symptoms of depression was higher in women more than 35 years of age (27.2%) and in second trimester of pregnancy (27.2%). Conclusion: Antenatal anxiety and depression are important issues because it impacts both maternal wellbeing and fetal health. Prevalence of anxiety and depression among pregnant women during COVID 19 pandemic was studied. The prevalence of anxiety and depression was 39.1% and 19% respectively.

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Perbedaan Kunjungan Pertama Ibu Hamil Berdasarkan Usia di Poskesdes Wilayah Kerja UPTD Puskesmas Gunungsari Kabupaten Lombok Barat

Indonesian Journal of Midwifery (IJM) ◽

10.35473/ijm.v2i2.288 ◽

2019 ◽

Vol 2 (2) ◽

Author(s):

Kusniyati Utami ◽

Irni Setyawati

Keyword(s):

Maternal Mortality ◽

Pregnant Women ◽

Health Workers ◽

Sampling Technique ◽

First Trimester ◽

P Value ◽

Antenatal Visit ◽

Chi Square ◽

Cross Sectional ◽

Significant Difference

The West Nusa Tenggara Provincial Health Office (2017) mentions the number of maternal mortality from 2015 to 2017 continues to decrease, from 95 cases to 85 cases. Maternal mortality during pregnancy can be prevented by antenatal care by health workers in accordance with the frequency of antenatal visits a minimum of four times. The first visit is carry out at a gestational age of the mother <16 weeks (Ministry of Health Republic of Indonesia, 2013), but still found pregnant women who made the first antenatal visit in the second trimester and even the third trimester.The purpose of this study was to determine the differences in first visit of pregnant women by age in the Poskesdes working area of the UPTD Puskesmas Gunungsari.This study used a cross-sectional analytic research design in eight Poskesdes in the working area of the UPTD Puskesmas Gunungsari, West Lombok district in November 2018 to January 2019. Samples were taken using a total sampling technique of 1042 people.Secondary data was collected from the maternal cohort register in eight Poskesdes in the UPTD Puskesmas Gunungsari working area in the form of the age of the mother at the first visit and the age of the mother's pregnancy at the first visit. Data were processed univariately and bivariately using the chi-square test.There was a significant difference in the first visit of pregnant women between mothers aged <20 years, 20-35 years, and> 35 years as indicated by the p value of 0.00001 (<0.05). It is expected that midwives in Poskesdes will further enhance the role of cadres in capturing first trimester pregnant women especially those aged <20 years and> 35 years.

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Evaluation of perineal muscle strength in the first trimester of pregnancy

Revista Latino-Americana de Enfermagem ◽

10.1590/0104-1169.3600.2492 ◽

2014 ◽

Vol 22 (6) ◽

pp. 893-901 ◽

Cited By ~ 4

Author(s):

Adriana de Souza Caroci ◽

Maria Luiza Gonzalez Riesco ◽

Bianca Moraes Camargo Rocha ◽

Letícia de Jesus Ventura ◽

Sheyla Guimarães Oliveira

Keyword(s):

Muscle Strength ◽

Pregnant Women ◽

Pelvic Floor Muscle ◽

First Trimester ◽

Cross Sectional ◽

Cesarean Deliveries ◽

Digital Palpation ◽

Vaginal Deliveries ◽

Significant Difference ◽

History Of

OBJECTIVES: to analyze the Pelvic Floor Muscle Strength (PFMS) of pregnant women with one or more vaginal or cesarean deliveries; to compare the PFMS of these with pregnant women with the PFMS of primiparous women.METHODS: cross-sectional study with women up to 12 weeks pregnant, performed in Itapecerica da Serra, São Paulo state, from December 2012 to May 2013. The sample consisted of 110 pregnant women with one or more vaginal deliveries or cesarean sections and 110 primigravidae. The PFMS was evaluated by perineometry (Peritron(tm)) and vaginal digital palpation (modified Oxford scale).RESULTS: the average PFMS in pregnant women with a history of vaginal delivery or cesarean section was 33.4 (SD=21.2) cmH2O. From the Oxford scale, 75.4% of the pregnant women with previous vaginal or cesarean deliveries presented grade ≤ 2, and 5.5% grade ≥ 4; among the primiparae, 39.9% presented grade ≤ 2, and 50.9% grade ≥ 4, with a statistically significant difference (p<0.001). From the perineometry, there was no statistically significant difference between the PFMS and age, type of delivery, parity, body mass index, and genitourinary tract symptoms, however, there was a statistically significant difference between the pregnant women with and without a history of episiotomy (p=0.04). In the palpation, none of the variables showed a statistically significant difference.CONCLUSION: pregnancy and childbirth can reduce the PFMS.

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Antibiotic Prescriptions among China Ambulatory Care Visits of Pregnant Women: A Nationwide Cross-Sectional Study

Antibiotics ◽

10.3390/antibiotics10050601 ◽

2021 ◽

Vol 10 (5) ◽

pp. 601

Author(s):

Houyu Zhao ◽

Mei Zhang ◽

Jiaming Bian ◽

Siyan Zhan

Keyword(s):

Pregnant Women ◽

Ambulatory Care ◽

National Level ◽

Mainland China ◽

Antibiotic Use ◽

First Trimester ◽

Cross Sectional Study ◽

Cross Sectional ◽

Fetal Safety ◽

First Trimester Of Pregnancy

Background: Antibiotic use in pregnant women at the national level has rarely been reported in China. Objectives: We aimed to investigate antibiotic prescriptions during pregnancy in ambulatory care settings in China. Methods: Data of 4,574,961 ambulatory care visits of pregnant women from October 2014 to April 2018 were analyzed. Percentages of Antibiotic prescriptions by different subgroups and various diagnosis categories and proportions of inappropriate antibiotic prescriptions for different subgroups were estimated. Food and Drug Administration (FDA) pregnancy categories were used to describe the antibiotic prescription patterns. The 95% confidence intervals (CIs) were estimated using the Clopper––Pearson method or Goodman method. Results: Among the 4,574,961 outpatient visits during pregnancy, 2.0% (92,514 visits; 95% CI, 2.0–2.0%) were prescribed at least one antibiotic. The percentage of antibiotic prescriptions for pregnant women aged >40 years was 4.9% (95% CI, 4.7–5.0%), whereas that for pregnant women aged 26–30 years was 1.5% (95% CI, 1.4–1.5%). In addition, percentages of antibiotic prescriptions varied among different trimesters of pregnancy, which were 5.4% (95% CI, 5.3–5.4%) for the visits in the first trimester of pregnancy and 0.5% (95% CI, 0.4–0.5%) in the third trimester of pregnancy. Furthermore, the percentages of antibiotic prescriptions substantially varied among different diagnosis categories and nearly three-quarters of antibiotic prescriptions had no clear indications and thus might be inappropriate. In total, 130,308 individual antibiotics were prescribed; among these, 60.4% (95% CI, 60.0–60.8%) belonged to FDA category B, 2.7% (95% CI, 2.1–3.5%) were classified as FDA category D and 16.8% (95% CI, 16.2–17.4%) were not assigned any FDA pregnancy category. Conclusions: Antibiotic prescriptions in ambulatory care during pregnancy were not highly prevalent in mainland China. However, a substantial proportion of antibiotics might have been prescribed without adequate indications. Antibiotics whose fetal safety has not been sufficiently illustrated were widely used in pregnant women.

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The role of the platelet profile in the prediction of gestational diabetes

10.51271/kmj-0012 ◽

2021 ◽

pp. 50-54

Keyword(s):

Body Mass Index ◽

Blood Glucose ◽

Gestational Diabetes ◽

Pregnant Women ◽

Body Mass ◽

First Trimester ◽

Oral Glucose ◽

Mean Corpuscular Hemoglobin ◽

Lymphocyte Ratio ◽

Significant Difference

Objective: In our study, the results of oral glucose tolerance test (OGTT) and other hemogram parameters of pregnant women with and without gestational diabetes mellitus (GDM) were compared. The aim of our study is to investigate the benefit of these parameters in predicting GDM risk. Material and Method: The study was planned as a descriptive, retrospective and cross-sectional study. It was included 218 pregnant women who applied to the Gynecology and Obstetrics Clinic of Amasya Sabuncuoğlu Şerefeddin Training and Research Hospital between January 01, 2019 and January 31, 2020. It was examined complete blood count parameters, ultrasound findings, complete urinalysis, first trimester blood glucose, body mass index, age, and gravide parameters the patients we included in the study. The results were analyzed retrospectively and was evaluated the statistical significance relationship with gestational diabetes. Results: There was no statistically significant difference in age, body mass index (BMI), obesity status and number of gravida between the pregnant women who were examined and those without GDM (p> 0.05). The hemoglobin, platelet count, mean platelet volume (MPV), mean corpuscular volume (MCV), mean corpuscular hemoglobine (MCH), and mean corpuscular hemoglobin concentration (MCHC) values, and neutrophil, lymphocyte, monocyte and basophil counts, urine density and femur length were statistically significant. There was no difference (p> 0.05). No statistically significant difference was found in terms of neutrophile lymphocyte ratio (NLR), neutrophile monocyte ratio (NMR), platelet lymphocyte ratio (PLR), monocyte eosinophil ratio (MER), platelet MPV ratio (PMPVR), and platelet neutrophile ratio (PNR) values (p> 0.05) Conclusion: HbA1c, hematocrit and blood glucose in the first trimester may be predictors of GDM. In addition, we think that further studies are needed in a prospective design in more patients in terms of others parameters.

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Determinants of Antenatal Care Attendance among Pregnant Women Living in Endemic Malaria Settings: Experience from the Democratic Republic of Congo

Obstetrics and Gynecology International ◽

10.1155/2016/5423413 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7 ◽

Cited By ~ 12

Author(s):

Célestin Ndosimao Nsibu ◽

Célestin Manianga ◽

Serge Kapanga ◽

Esther Mona ◽

Philippe Pululu ◽

...

Keyword(s):

Antenatal Care ◽

Pregnant Women ◽

Democratic Republic ◽

Democratic Republic Of Congo ◽

Male Partner ◽

First Trimester ◽

Reproductive Age ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Republic Of Congo

Background. Antenatal care (ANC) attendance helps pregnant women to benefit from preventive and curative services.Methods. Determinants for ANC attendance were identified through a cross-sectional survey in the Democratic Republic of Congo. Sociocultural bottlenecks were assessed via focus groups discussion of married men and women.Results. In this survey, 28 of the 500 interviewed pregnant women (5.6%) did not attend ANC services and 82.4% booked over the first trimester. The first visit is positively influenced by the reproductive age (OR: 0.52, 95% CI(0.28–0.95),p<0.04), the educational level (OR: 0.41,95% CI(0.17–0.97),p<0.04), the nearby health center (OR: 0.43, 95% CI(0.2–0.92),p<0.03), and the presence of a male partner (OR: 10.48, 95% CI(2.1–52.23),p<0.001). The barriers to early booking were (i) the cost of service; (ii) the appearance or individual income; (iii) the geographical inaccessibility or distance to health facilities; (iv) social and religious prohibitions; (v) the stigmatization from other women when conceiving in the late ages or young or while still lactating (parity); (vi) the time for waiting for services.Conclusion. The early ANC attendance is delayed among poor women with little education and living alone.

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Cross-sectional study to assess etiology and associated factors for anaemia during first trimester of pregnancy in Anuradhapura District, Sri Lanka: a protocol

F1000Research ◽

10.12688/f1000research.28226.1 ◽

2021 ◽

Vol 10 ◽

pp. 223

Author(s):

Gayani Amarasinghe ◽

Vasana Mendis ◽

Thilini Agampodi

Keyword(s):

Sri Lanka ◽

Data Collection ◽

Pregnant Women ◽

Associated Factors ◽

First Trimester ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Anaemia In Pregnancy ◽

In Pregnancy

Background: Anaemia in pregnancy, which can lead to adverse maternal and fetal outcomes, is a significant global health problem. Despite Sri Lanka’s strong public health system and commitment towards prevention, maternal anaemia remains a major problem in the country. While prevention is focused on iron deficiency, detailed etiological studies on this topic are scarce. Moreover, estimates of socio demographic and economic factors associated with anaemia in pregnancy, which can provide important clues for anaemia control, are also lacking. This study aims to evaluate the hemoglobin distribution, spatial distribution, etiology and associated factors for anaemia in pregnant women in Anuradhapura, Sri Lanka. Methods: This is a cross sectional study of pregnant women in their first trimester registered for antenatal care from July to September 2019 in the Anuradhapura district. The minimal sample size was calculated to be 1866. Initial data collection has already been carried out in special field clinics for pregnant women between June to October 2019. An interviewer-administered questionnaire, a self-completed dietary questionnaire and an examination checklist were used for data collection. In addition, all participants underwent complete blood count testing. Further investigations are being conducted for predicting the etiology of anaemia based on a developed algorithm (such as high-performance liquid chromatography [HPLC] and peripheral blood film analysis). Discussion: Being the largest study on anaemia during pregnancy in a single geographical area in Sri Lanka, this study will provide important clues about geographical clustering of anaemia cases with similar etiology, associated factors and etiologies which would help to develop interventions to improve the health of pregnant women in the area. The possibility of selection bias is a potential limitation associated with the study design.

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Rapid Diagnostic Test Versus Microscopy for Diagnosing Malaria Among Pregnant Women in a Resource-Poor Setting; A Cross-Sectional Comparative Study

Global Journal of Health Science ◽

10.5539/gjhs.v12n8p52 ◽

2020 ◽

Vol 12 (8) ◽

pp. 52

Author(s):

Bartholomew N. Odio ◽

Leonard O. Ajah ◽

Perpetus C. Ibekwe ◽

Monique I. Ajah ◽

George O. Ugwu ◽

...

Keyword(s):

Pregnant Women ◽

Diagnostic Test ◽

Rapid Diagnostic Test ◽

Clinical Features ◽

Scale Up ◽

World Health ◽

Resource Poor Setting ◽

Cross Sectional ◽

Significant Difference ◽

Resource Poor

BACKGROUND: Diagnostic challenge of malaria in Nigeria remarkably impedes the World Health Organization (WHO) recommendation of laboratory diagnosis before treatment. Rapid Diagnostic Test (RDT) is easier and cheaper to perform when compared with microscopy especially in resource-poor settings. However there are conflicting results on the accuracy of RDT versus microscopy from previous studies. AIM: To compare the overall accuracy of   microscopy and RDT in detecting peripheral malaria among   pregnant women with clinical features of malaria. MATERIALS & METHODS: This was a cross-sectional comparative studyin whichRDT, microscopy and polymerase chain reaction (PCR) were performed using the peripheral bloodof the eligible study participants at the Alex Ekwueme Federal University Teaching Hospital, Abakaliki between September 1, 2016 and March 31, 2017.The PCR was used as the gold standard in this study. Data was analyzed with the Statistical Package for Social Sciences version 18 (IBM SPSS, Chicago, USA). P value ≤ 0.05 was considered statistically significant. RESULTS: The actual prevalent rates of malaria based on RDT, microscopy and PCR results among the participants were 58.2%, 59.9% and 61.1% respectively. There was no statistical significant difference among RDT, microscopy and combined RDT and microscopy on overall accuracy. Malaria infestation was associated with self-employed and unemployed women, primigravidity, second trimester, rural residence, non-use of long lasting insecticide treated nets and intermittent preventive therapy for malaria. CONCLUSION: There was no difference in overall accuracy among RDT, microscopy and combined RDT and microscopy. This underscores the need to scale up RDT for every patient with clinical features of malaria before treatment in this environment.

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