scholarly journals Adverse Events of Risperidone and Clozapine Combination Therapy on Schizophrenic Patients at Magelang Mental Hospital

2021 ◽  
Vol 10 (3) ◽  
pp. 159-171
Author(s):  
Gilang R. Al Farizi ◽  
Dyah A. Perwitasari ◽  
Haafizah Dania ◽  
Melisa I. Barliana ◽  
Santi Yuliani

The adverse drug effect of risperidone and clozapine combination therapy possibly increases the BMI, systolic and diastolic blood pressures of mental victims. This study aimed at determining the relationship between the duration of risperidone and clozapine combination therapy and increase in body mass index (BMI), systolic and diastolic blood pressures of schizophrenic patients. The correlation was obtained using the cohort retrospective method on 59 schizophrenic inpatients at Magelang Mental Hospital from February–May 2019. Participants were grouped into 2 categories, termed <8 and ≥8 weeks with 48 and 11 persons, respectively. Subsequently, patients’ BMI, systolic and diastolic blood pressures were measured during the first day of hospitalization and outpatient consultations, based on NCEP-ATP III cut off-point with the modification of Southeast Asian population’s BMI. Structured questionnaires were used to evaluate calory intake and physical activity as well as generate respondents’ medical records. The bivariate analysis results showed a significant relationship between BMI increase at initial hospitalization and during outpatient consultation on group ≥8 weeks therapy, 22.41±2.98 kg/m2 vs 25.2±6.80 kg/m2 (p=0.023, –2.75 (–5.12–(–0.39)). However, there is no major correlation occurred in systolic 117±11.73 mmHg vs 118±15.42 mmHg (p=0.797, 95%CI –1.07 (–9.41–7.26)) and diastolic blood pressures 76±7.86 mmHg vs 73±8.48 mmHg (p=0.192, 95% CI 3.52 (–1.81–8.86)) for both groups. Furthermore, age, gender, smoking status, dosage, co-medication, calory intake and physical activity indicated no substantial variations, in terms of the increase in BMI, systolic and diastolic blood pressures among two categories.

2009 ◽  
Vol 6 (3) ◽  
pp. 315-320 ◽  
Author(s):  
Mohamad Al-Tannir ◽  
Samer Kobrosly ◽  
Taha Itani ◽  
Mariam El-Rajab ◽  
Sawsan Tannir

Background:This survey aims to assess the prevalence of physical activity among adult Lebanese, and to report the relationship between sociodemographic variables and physical activity behavior, highlighting the correlates discouraging people to carry out physical activity.Methods:A cross-sectional study using an anonymous self-reported questionnaire was conducted on 346 adults from four Lebanese districts. Demographic characteristics, physical activity, smoking status, alcohol consumption, and medical history were obtained.Results:Prevalence of physical activity among Lebanese adults was 55.5% (192/346). Age, BMI, marital status, medical history, occupation, educational level, and smoking were significantly associated with physical activity (P < .05). Inactive obese participants were about three times more likely to report hypertension and diabetes than inactive normal weight participants (P = .013). BMI was significantly higher among inactive participants (P = .014).Conclusion:Physical activity among Lebanese adults was comparable to other populations. Married, non–office workers, and smokers were the main correlates of physical inactivity in Lebanese adulthood.


1992 ◽  
Vol 160 (2) ◽  
pp. 230-241 ◽  
Author(s):  
David A. Curson ◽  
Christos Pantelis ◽  
Jan Ward ◽  
Thomas R. E. Barnes

In their comparison of chronic schizophrenic patients in three British mental hospitals in 1960, Wing and Brown found a strong association between the poverty of the social environment and the severity of ‘clinical poverty’ (blunted affect, poverty of speech, and social withdrawal). Between 1960 and 1968 the social environments of all three hospitals improved and a weak causal relationship between social poverty and clinical poverty was reported in a proportion of patients. Using the same assessment instruments as Wing and Brown, the present study re-examined the relationship between social and clinical poverty in the long-stay schizophrenic population of a fourth British mental hospital in 1990. The association found between social and clinical poverty was much weaker than in 1960. Reluctance on the part of patients to be discharged from the institution was unrelated to length of stay. There was no significant difference in severity of illness between the patients in the present study and those in the earlier study. However, patients in the former group spent more time doing nothing than those in the hospital with the most understimulating environment three decades before, with four-fifths doing nothing for over five hours a day, despite a greatly increased ratio of nurses to patients.


2020 ◽  
Vol 11 (1) ◽  
pp. 114-120
Author(s):  
Magdalena Magdalena Agu Yosali ◽  
Dr. Astry Dr. Astry

The Maternal Mortality Rate (MMR) is one indicator that can describe the welfare of the community in a country. According to the World Health Organization (WHO) in 2012 as many 99% of maternal death’s were caused by labor problems. The Maternal Mortality Rate (MMR) in developing countries is the highest compared to MMR in the depeloved countrieswith a total 450 deaths/ 100.000 live births. This is very important, considering the high MMR associated with pregnancy, childbirt, nipas, beside being coused due to complication also coused by several complicating factor of labor that effect the length of labor, including age, parity, distance of pregnancy, activity during pregnancy, antenatal care visit. This type of research is quantitative analytical methods. The study was conducted at the Sindang Barang health center Bogor City in 2018, totaling with 45 respondents. Using the total sampling technique. The instrument used were physical activity questionnaires and partograph sheets while data analysis techniques used univariate and bivariate analysis. In the statistical test of study of the relationship between maternal physical activity and the length of labor in Sindang Barang Health Center Bogor city 2018, it can be concluded that there are 20 (44,44%) mothers with long-term labor activity > 24 hours, there are 1 (22,2%) mothers with heavy activity that experience normal labor < 24 hours, there 9 (24,4%) mothers with strenuous activity who experience prolong labor > 18 hours, there are 2 (4,45%) mothers with heavy activity who experience < 18 hours. There are 1 (2,22%) mothers with mild activity who experience prolonged labor > 24 hours, there are 3 (6,67%) mothers with mild activity who experience normal labor < 24 hours, there are 2 (4,45%) mothers with mild activity who experience prolonged labor > 18 hours, there are 7 (15,55%) mothers with mild activity who experience normal delivery < 18 hours. Based on the results of the value of P value 0.000 is obtained so that the alternative hypothesis is accept and the null hypothesis is riject. So that there is Relationship between Mother’s physical Activity and the Length of Labor in the Sindang Barang Health Center in Area Bogor City 2018. 


2016 ◽  
Vol 116 (5) ◽  
pp. 874-881 ◽  
Author(s):  
Fariba Bagheri ◽  
Fereydoun Siassi ◽  
Fariba Koohdani ◽  
Behzad Mahaki ◽  
Mostafa Qorbani ◽  
...  

AbstractPre-diabetes increases the risk of diabetes and CVD. Several studies have investigated the relationship between food intake and pre-diabetes morbidity, but the dietary patterns of pre-diabetes subjects were not taken into consideration. The aim of this study was to determine the relationship between dietary patterns and pre-diabetes. In this regard, 150 pre-diabetic subjects and 150 healthy controls, who attended the diabetes screening centre in Shahreza, Iran, were matched for age group and sex. The weight, height, waist circumference, physical activity, systolic and diastolic blood pressures, and blood glucose levels of all participants were measured. Dietary information was collected using a semi-quantitative FFQ. Using factor analysis, two dietary patterns were identified: the vegetables, fruits and legumes (VFL) dietary pattern and the sweet, solid fat, meat and mayonnaise (SSMM) dietary pattern. Multivariate logistic regression was used to assess the relationship between pre-diabetes and dietary patterns. After adjusting for age, education, physical activity, BMI and energy intake, the VFL dietary pattern was found to be negatively associated with lower pre-diabetes (OR 0·16; 95 % CI 0·10, 0·26). Furthermore, the SSMM dietary pattern was positively associated with pre-diabetes (OR 5·45; 95 % CI 3·22, 9·23). In conclusion, the VFL dietary pattern is inversely related to pre-diabetes, whereas the SSMM dietary pattern is associated with increased risk of pre-diabetes.


2021 ◽  
pp. 55-67
Author(s):  
Eka Risdayani ◽  
Armanto Makmun

Background: Obesity is a condition of excess fat accumulation in the body's adipose tissue which can be influenced by physical activity, food intake, genetic factors, sleep habits, age and gender. The incidence rate in Indonesia tends to increase as seen from the Riskesdas 2007, 2013 and 2018 data, namely 10.5%, 14.8%, and 21.8%. Objective: To determine the relationship between obesity and age, gender, level of physical activity, eating habits, genetics and sleep duration. Methods: This research is a quantitative study with a cross sectional approach. Data collection was carried out through a questionnaire. The research sample is a sample with overweight and obesity obtained a sample of 80 samples. The data analysis was conducted, namely univariate and bivariate analysis using the chi-square test. Results: 36.3% of respondents are overweight and 63.8% obese. Most of the respondents were> 18 years old. The results showed that obesity was significantly associated with age (p = 0.016), gender (p = 0.010), physical activity (p = 0.025), frequency of eating (p = 0.015), frequency of heavy eating (p = 0.040), drinking- sugary drinks (0.025), fast food (p = 0.025) daily portions of food (p = 0.025) and a family history of obesity (p = 0.007). Conversely, consumption of snacks (p = 0.731), consumption of fibrous foods (p = 0.089), the relationship between breakfast (p = 0.776), the relationship between sleep time (p = 0.243). Conclusion: Age, gender, physical activity, frequency of eating, frequency of heavy eating, drinking sugary drinks, consumption of fast food, daily food portions and a family history of obesity have a significant relationship which can be a contributing factor to obesity


Food Research ◽  
2020 ◽  
Vol 4 (S3) ◽  
pp. 99-108
Author(s):  
D.K. Pradita ◽  
F.F. Dieny ◽  
D.M. Kurniawati ◽  
A.F.A. Tsani ◽  
N. Widyastuti ◽  
...  

The iron deficiency that occurs in young female athletes can cause a decrease in bone density in three mechanisms, through the process of hydrolysis of procollagen formation, metabolism along with vitamin D and hypoxia. The aimed of this study is to analyze the relationship of iron deficiency with bone density in young female athletes. A crosssectional study design with 70 athletes aged 12-21 years conducted at the BPPLOP Central Java, Salatiga Athletics Club and Athletics and Swimming Club Semarang State University. Iron deficiency was determined by levels of ferritin serum, bone density measured by Bone Densitometer Quantitative Ultrasound, body fat percentage and muscle mass measured by Body Composition Analyzer. Bone-specific Physical Activity Questionnaire was used for physical activity data. Nutrition intakes such as protein, calcium, vitamin D, phosphorus, iron, potassium, magnesium, and sodium was collected by Semi Quantitative-Food Frequency Questionnaire. This study used bivariate analysis with Pearson and Rank-Spearman Correlation Tests and multivariate analysis with Multiple Linear Regression Test. A young female athlete who suffers from iron deficiency is approximately 14.3%. All subjects had normal bone density. Significant relationships were observed between iron deficiency based on serum ferritin (p = 0.044) and muscle mass (p = 0.002) with bone density on young female athletes. The muscle mass variable had the strongest influence on bone density (p = 0.002; adjusted R2 = 0.117). This study showed that iron deficiency and muscle mass are related to bone density, but the other factors that might have an impact on bone density must be considered.


2005 ◽  
Vol 2 (4) ◽  
pp. 470-487 ◽  
Author(s):  
Katrina D. DuBose ◽  
Cheryl L. Addy ◽  
Barbara E. Ainsworth ◽  
Gregory A. Hand ◽  
J. Larry Durstine

Background:This study was performed to determine the relationship between leisure-time physical activity (LTPA) and the metabolic syndrome (MS) in 16,681 adults (43 ± 0.44 y) enrolled in NHANES III.Methods:LTPA was classified as regularly active (≥ 5 d/wk moderate and/or ≥ 3 d/wk vigorous), irregularly active (some LTPA), or inactive (no LTPA). The MS was positive with three or more conditions: 1) abdominal obesity, 2) low HDL-C, 3) hypertriglyceridemia, 4) elevated blood pressure, or 5) elevated glucose. Logistic regression examined the relationship between LTPA and the MS, adjusting for age, race, smoking status, and educational attainment stratified by gender.Results:In men only, irregular activity and inactivity was related to an increase in the MS (irregular: OR = 1.52 95% CI 1.11, 1.23; inactive: OR = 1.60, 95% CI 1.18, 1.98; test for trend P = 0.004). Inactivity increased the odds for abdominal obesity (P < 0.05).Conclusions:LTPA levels might influence the development of MS and abdominal obesity.


2019 ◽  
Vol 14 (4) ◽  
pp. 442-448
Author(s):  
Jafar Sadegh Tabrizi ◽  
Mostafa Farahbakhsh ◽  
Homayoun Sadeghi-Bazargani ◽  
Hossein Mashhadi Abdolahi ◽  
Zeinab Nikniaz ◽  
...  

ABSTRACTObjective:This study investigated the health effects of Lake Urmia’s drought on adjacent urban and rural areas and people.Methods:The data for sociodemographic status, physical activity, dietary pattern, smoking, and angina of the subjects living in areas adjacent to and far from Lake Urmia were collected through validated questionnaires. Physical examinations, including blood pressure, anthropometrics, and biochemical measurements, were performed.Results:There were no significant differences between 2 areas in the case of age, sex, educational, and physical activity and smoking status (P > 0.05). The mean systolic and diastolic blood pressures and the prevalence of hypertension, prehypertension, and anemia in cases living in the adjacent areas were significantly higher than those in the control group (P < 0.05). No significant differences were observed between 2 districts in the prevalence of hyperlipidemia, overweight/obesity, asthma, angina, infraction, diabetes, and vitamin D insufficiency/deficiency.Conclusions:Our data showed that Lake Urmia’s drought has serious effects on hypertension and anemia. More longitudinal and well-designed studies are needed to confirm these results.


2021 ◽  
Vol 5 (1) ◽  
pp. 1-8
Author(s):  
Yasmin Az Zahrah ◽  
Liya Arista

The fast-food online diet can outweigh obesity. The research was conducted on students because students were at the stage of adulthood where metabolism slows down and the trend of ordering food online is mostly done by students. This study identified the relationship between fast food online diet, physical activity, and genetic history with obesity. The research design used was cross sectional with a population of all University X students class 2016-2019 and a total sample of 164 respondents. Data obtained from the FFQ and IPAQ questionnaire sheets through the online G-form. The results of the bivariate analysis with the Chi-Square test showed that there was no significant relationship between online fast food eating patterns and BMI / obesity (p> 0.005), likewise for physical activity variables also did not show a significant relationship with obesity (p = 0.746) However, for genetic history, there was a significant association with obesity (p


2021 ◽  
pp. 1-3
Author(s):  
Antonis Th. Theofilidis ◽  

Adolescence is a phase of developmental growth between childhood and adulthood. In 2013 the number of teenagers was 65 million people or 30% of the population of Indonesia. Parents find it taboo to talk about sex issues so teenagers are looking for alternative sources of information. Teenagers use mass media as a source of information. This study was to find out the relationship of social media use with the level of knowledge about free sex in adolescents at SMA Negeri 12 Makassar. Research design uses analytical surveys with a cross sectional approach. Sampling was with simple random sampling techniques. The number of respondents was 105 students. Data collection is done using questionnaires. Data analysis includes univariate analysis by looking for frequency distribution, bivariate analysis with Chi-Square test α = 0.05 to find out the relationship between variables. The results of the analysis of bivariate obtained a relationship between social media and the level of knowledge about free sex (p= 0.002). The conclusion in this study is that there is a strongly relationship between the use of social media and the level of knowledge about free sex in adolescents.


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