scholarly journals Influence of iron (IV) clathrochelate complexon quail blood parameters and weight characteristics

2019 ◽  
Vol 9 (3) ◽  
pp. 126-131
Author(s):  
V. B. Dukhnitsky ◽  
I. M. Derkach ◽  
S. S. Derkach ◽  
I. O. Fritsky ◽  
M. O. Plutenko

We studied the chronic toxicity of the compounds of Iron(iv). We monitored the dynamics of the body weight, relative weight coefficients of the internal organs, the content of the hemoglobin, the morphological parameters of blood, and biochemical parameters of serum of blood of quails after use of Iron(IV) clathrochelate complexes at the doses 1/10 and 1/5 DL50 them for 30 days. Daily drinking of quails of experimental groups of solution of Iron(IV) clathrochelate complexes3 at the doses 76.43 and 152.86 mg/kg of body weight caused the reduction of body weight by 3 and 5% respectively on the thirtieth day. A tendency to increase the relative weight of the kidneys and to decrease the relative weight of the liver, heart and spleen showed an excessive load of Iron(IV) clathrochelate complexes on the internal organs of quails. Hemoglobin in the blood of the quails of the experimental groups was less by 2-34% (P 0.05) than the control indicator but the indicator of the number of erythrocytes in the quails of the control and experimental groups for 30 days was within the physiological values. The use of Iron(IV) clathrochelate complexes caused the development of hypoproteinemia, hypoalbuminemia, and short-term hypoglycemia in the serum of the blood of the quails of the experimental groups. Changes in an activity of alanine aminotransferase and aspartate aminotransferase for 30 days were not expressed, but the activity of alkaline phosphatase was significantly higher compared to the control indicators during the experimental period. Drinking the solution of Iron(IV) clathrochelate complexes caused hypercreatinemia and hyperuricemia, which indicates a decrease in the filtration capacity of the kidney glomeruli. We have seen an increase in the levels total Calcium and inorganic Phosphorus.

2019 ◽  
Vol 21 (95) ◽  
pp. 15-21
Author(s):  
V. B. Dukhnitsky ◽  
I. M. Derkach ◽  
S. S. Derkach ◽  
I. O. Fritsky ◽  
M. O. Plutenko

The article presents the results of studies of chronic toxicity of the Iron in the rare unconventional valence – IV. During long-term use of the Iron(IV) clathrochelate complexes for white rats we have established the dynamics of the body weight of rats, the relative coefficients of mass of the internal organs, the content of hemoglobin and morphological parameters of blood, biochemical parameters of blood serum of animals of this species. The daily drinking of solution of the Iron(IV) clathrochelate complexes at the doses of 500 and 1000 mg/kg b. w. resulted in a decrease in body weight, an increase in the relative indices of masses of liver and kidney, and a decrease in the relative indices of masses of  spleen and heart on 30th day. The hemoglobin content in the blood of rats of the experimental group was less than the control indicator by 3–47% (P < 0.05), which is evidence of inhibition of its synthesis under the influence of the Iron (IV) clathrochelatе. Changes in the morphological composition of the blood were characterized by marked leukocytopenia. The use of rats of a solution of the Iron (IV) clathrochelate complexes at doses of 500 and 1000 mg/kg b. w. caused the development of hypoproteinemia, hypercreatinemia and hyperurinemia. Iron(IV) clathrochelate complexes reduced alaninaminotransferase activity in the serum of rats of both experimental groups by 15–80% (P < 0.05); aspartataminotransferase activity increased significantly by day 10 and decreased by day 30; the activity of alkaline phosphatase was independent of the doses of the drug during the experimental period. The content of Calcium total, Phosphor inorganic and Iron in the serum of rats of the experimental groups was at the level of indicators in the animals of the control group. Consequently, comprehensive studies of the effects of solution of the Iron (IV) clathrochelate complexes at doses of 500 and 1000 mg/kg b. w. were performed for the first time with long-term administration to white rats, which revealed the main patterns of metabolic disorders and physiological functions.


2020 ◽  
Vol 45 (2) ◽  
pp. 40-48
Author(s):  
A. J. Atansuyi ◽  
U. C. Ihendu ◽  
C. A. Chineke

This study was conducted to determine the growth performance, correlation and regression estimates of seven-chicken strains in South-western Nigeria using a total of 300 day-old chicks. The birds were divided into seven groups based on their strain. The seven strains are Normal feather (NF), Fulani ecotype (FE), Frizzle feather (FF), naked neck (NN) and Transylvania indigenous strains while Hubbard and Marshal were meat-type exotic chickens. There were forty- five (45) unsexed day-old chicks in each strain except the Frizzle feather that were 30 in number. Completely randomized design (CRD) was used for the trial that lasted for 8 weeks. The birds were fed experimental diets ad libitum throughout the period of the study. Results showed that there were significant differences (p<0.05) in the initial and final weights of the birds. It was observed that exotic strains weighed heavier (3569.73gHB) than their indigenous counterparts (1391.11gNF). However, the Fulani ecotype weighed heaviest (1840.99g) among Nigeria indigenous strains during the experimental period. This showed that FE strains are generally heavy breed chicken and could be incorporated into a meat producing indigenous chicken if improved upon. The result of the correlation coefficients showed that a very strong, positive and highly significant (P<0.001) relationship existed between body weights and linear body measurements as most of the values are (>0.40). All the body parameter examined had significant (p<0.01) and direct relationship with the body weight. Shoulder-to-tail length (STL) had the highest coefficient of 0.98.The high correlation estimates obtained in this study could be as a result of pleiotropy, heterozygosity or linkage of genes in the birds. The three functions were highly significant (p<0.05) for all the parameters studied. This shows that the functions well described the parameters. On the basis of coefficient of determination (R ), the body weight of poultry birds at any age can be predicted most accurately with BRG using cubic function.


2010 ◽  
Vol 39 (7) ◽  
pp. 1548-1557 ◽  
Author(s):  
Nelson Massaru Fukumoto ◽  
Julio Cesar Damasceno ◽  
Fermino Deresz ◽  
Carlos Eugênio Martins ◽  
Antônio Carlos Cóser ◽  
...  

The objective of this study was to evaluate milk yield and composition, dry matter intake, and stocking rate in pastures with tanzania grass (Panicum maximum cv. Tanzânia), star grass (Cynodon nlemfuensis cv. Estrela-Africana), and marandu grass (Brachiaria brizantha cv. Marandu). The grasses were managed in a rotational grazing system with Holstein x Zebu crossbreed cows, with a 30-day resting period and three days of paddock occupation. The pastures were fertilized with 1,000 kg/ha/year using the 20:05:20 (NPK) formula, split in three applications during the rainy season. It was used a complete random block experimental design with three factors being studied and two replications. In the experiment, four cows/paddock were used and, when it was necessary, regulator animals were added in order to obtain a supply of 7% body weight green forage dry matter. The animals were individually fed concentrate at 2 kg/day during the experimental period. Milk yield did not differ among the three grasses, with values of 9.1; 9.1; and 8.7 kg/cow/day for pastures with tanzania grass, star grass and marandu grass, respectively. Similarly, grass did not affect milk chemical composition. Stocking rate was similar among the three grasses, with values of 4.6; 4.5 and 5.0 UA/ha for tanzania grass, star grass and marandu grass, respectively. The highest dry matter intake was observed for tanzania grass with 2.6% of the body weight while stargrass (2.3%) and marandu grass (2.4%) did not differ among each other. The highest dry matter intake on tanzania grass pasture was not reflected on milk yield per animal. Milk yield and composition and stocking rate are similar among the evaluated grasses.


Rangifer ◽  
2000 ◽  
Vol 20 (4) ◽  
pp. 187 ◽  
Author(s):  
A. Nilsson ◽  
Ö. Danell ◽  
M. Murphy ◽  
K. Olsson ◽  
B. Åhman

The transition from experimentally induced poor nutritional conditions to feeding was studied with 69 eight-month-old female reindeer (Rangifer tarandus tarandus). During a pre-experimental period, all reindeer were fed a simulated winter diet with 80% lichens Cladina spp. and 20% Vaccinum myrtillus shrubs and Salix spp. leaves (lichen diet) ad lib. The reindeer were divided into five groups. A control group (group C) was fed the lichen diet ad lib. throughout the experiment. Four groups were fed half of that ration for eight days and were then totally deprived of feed for one day (restriction period). During the following 34 days (feeding period) the groups were re-fed the lichen diet (group L), fed pelleted reindeer feed combined with either lichen (group PL) or grass silage (group PS), or fed silage with a gradually increasing addition of pellets (group SP). Weekly measurements of blood samples and body weighr showed that the control group remained clinically healthy and had stable blood plasma concentrations of protein, urea, glucose and insulin throughout the experiment, but they lost weight. At slaughter, before and after the restriction period, all animals had lost rumen-free body weight, but the reindeer fed a restricted amount of feed lost more than the control group. Also the plasma metabolites were affected by the restricted feeding, with increased concentrations of urea and decreased concentrations of glucose. Group L responded immediately to the ad lib. feeding with blood metabolite levels rapidly approaching those of group C. The body weight developments were similar in groups L and C. Although the feed rations were increased gradually, diarrhoea occurred in some animals belonging to groups PL and PS within the first week of the feeding period. All reindeer recovered, after antibiotic treatment of the worst affected animals. The PL and PS groups, which had high contents of metabolisable energy and crude protein in their diets, showed increased con-centtations of plasma protein, urea and insulin. At the end of the feeding period, these groups had increased their body and carcass weights and gained fat, whereas reindeer fed the lichen diet had lost weight. Severe health problems (malnutrition and so-called wet belly) occurred in group SP during the first weeks of feeding and led to loss of animals, and consequently the SP group was excluded from the remainder of rhe experiment. The general conclusion is that the lichen diet did not cause any digestive problems, but resulted in a continuous decline in body weight and small or deficient fat reserves. After the initial diarrhoea, feeding with diets comprising pellets from the start resulted in improved condition, expressed as increased body weight, fat gain and higher concentrations of plasma protein, urea and insulin in relation to the control group. The diet initially based on grass in the form of silage of the given quality seemed insufficient as feed to reindeer calves in a poor nutritional state.


ZOOTEC ◽  
2019 ◽  
Vol 39 (2) ◽  
pp. 233
Author(s):  
Jein Rinny Leke ◽  
F.N. Sompie ◽  
E. Wantasen ◽  
T. Widyastuti ◽  
E.H.B. Sondakh

INTERNAL ORGANS CHAR ACTERISTICS OF NATIVE CHICKEN FED BY COCONUT OIL (Cocos nucifera) ON DIET. The research was carried to determine the internal organs characteristics of buras chickens fed coconut (Cocos mucifera) oil in diet. A total 100 unsexed buras chickens was used in this experiment. The design used in this study was a completely randomized design (CRD) consisting of 5 treatments and 5 replications (4 hens each). The data were subjected to analysis of variance, when the treatments indicated significant effect it was continued Duncan’s Multiple Range Test. Five dietary treatments containing 0, 0.5%, 1 %, 1,5%, and 2% levels of coconut oil (CO) with five replicates were applied to chickens.  Parameters measured were body weight, heart, liver, pancreas  and gizzard weight. Result showed that CO in the ration significantly increased the body weight (P<0.01) but did not affect to heart weight, liver weight, pancreas weight and gizzard weight.(P>0.05) It can be concluded that coconut oil in the diet can’t increase the internal organ characteristics. We can gave the 2% CO in the diet for the best results. Key words: Internal Organs, Coconut Oil, Buras Chickens


2021 ◽  
Vol 10 (2) ◽  
pp. 89-97
Author(s):  
EL Lappa ◽  
◽  
C Bogning Zangueu ◽  
EL Nguemfo ◽  
JJ Kojom Wanche ◽  
...  

Ficus vogelii is a medicinal plant mainly found in tropical Africa and reported to treat inflammatory complaints. This study aims to evaluate the acute and sub-chronic toxicity of the aqueous extract of Ficus vogelii stem bark in wistar rats. For acute study, aqueous extract at a single dose of 5000 mg/kg body weight was administered to female rats and observed for 14 days. In the sub-chronic study, the extract was administered daily to both sex rats at the doses of 100, 200, 400, and 600 mg/kg body weight for 28 consecutive days. Body weight was measured weekly, while hematological, biochemical, and histopathological parameters were analyzed after euthanize. Aqueous extract of Ficus vogelii at all tested doses didn’t produced any mortality or significant change on the body weight and relative weight of rats on acute and sub-chronic studies. The lethal dose 50 was estimated greater than 5000 mg/kg (DL50˃5000 mg/kg). Hematological parameters were recorded non-significant in all treated rats. Aqueous extract at 600 mg/kg significantly changed transaminases and alkaline phosphatase activities, these changes were reversible in satellites. The concentrations of bilirubin was increased at 200 and 600 mg/kg in male rats, at 100, 400 mg/kg in female rats. The levels of lipids markers didn’t changed, except the significant decrease of LDL-cholesterol. Histological examination didn’t showed any change in the architecture of the liver and kidney of rats treated compared to control. Thus aqueous extract of Ficus vogelii stem bark didn’t produced adverse effects in rats after oral acute and sub-chronic treatment.


1957 ◽  
Vol 8 (1) ◽  
pp. 75 ◽  
Author(s):  
PK Briggs ◽  
MC Franklin ◽  
GL McClymont

Dry adult Merino ewes were fed at daily or weekly intervals on oat grain at levels which provided 4.0, 3.0, or 2.0 lb starch equivalent (S.E.) per sheep per week. The experimental periods were 223, 223, and 181 days respectively. Differences between the mean body weights of the ewes a t the three levels of feeding were highly significant (P < 0.001). Body weight varied only slightly and no losses occurred in ewes fed weekly at the rate of 4.0 lb S.E. per head. Ewes fed daily a t this level had a significantly greater mean body weight (P < 0.001) a t the conclusion of the 223-day experimental period. The addition of a sodium chloride supplement did not improve the body weight or wool production of ewes fed weekly a t the level of 4.0 lb S.E. The mean body weight of ewes fed at the levels of 3.0 or 2.0 lb S.E. per head declined over the first 12 and 18 respectively and thereafter remained relatively constant. There were no significant differences at these levels of feeding between groups fed daily and weekly in respect of body weight, wool production, or survival rates. Ewes fed a t the level of 4.0 lb S.E. grew significantly more wool than those given 3.0 lb S.E. (P < 0.001). Losses were negligible in all groups except those fed a t the level of 2.0 lb S.E. In these groups there were few deaths in the first 16 weeks, but in the subsequent 10 weeks losses totalled 17.1 per cent. Ewes fed a t the level of 2.0 lb S.E. consumed their rations at a significantly slower rate (P < 0.01) than did those fed a t the level of 4.0 lb S.E.


Animals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 963 ◽  
Author(s):  
Dariusz Kokoszyński ◽  
Rafał Wasilewski ◽  
Mohamed Saleh ◽  
Dariusz Piwczyński ◽  
Henrieta Arpášová ◽  
...  

Native breeds of ducks have been the subject of many studies in the past, yet the relevant knowledge is still incomplete and needs to be further expanded. The objective of this study was to provide information about differences in growth performance, dressing percentage, carcass composition and digestive morphometry among three lines of Pekin ducks from conservation flocks raised in Poland. The study used 180 sexed Pekin ducks—30 males and 30 females of line P33 (ducks of Polish origin), 30 males and 30 females of line P8 (ducks of Danish origin), and 30 males and 30 females of line P9 (ducks of French origin). Throughout the study (49 d), ducks were confined indoors in six pens. Birds were fed complete commercial diets ad libitum and had unrestricted access to water. The compared lines of ducks differed significantly in body weight from 1 to 49 d of age except of ducks of both sexes at 14 d. At 49 d of age, significant differences were observed between the tested ducks in all the body measurements. Duck genotype had a significant effect on preslaughter body weight, carcass weight and breast muscle, neck and remainders contents, caeca length, liver weight and gizzard percentage. The results show that the tested ducks were significantly different and unique, mainly in terms of the body biometric characteristics.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 112-112
Author(s):  
Wenliang He ◽  
Erin A Posey ◽  
Guoyao Wu

Abstract Pigs with intrauterine growth restriction (IUGR) represent 20–25% of all pigs born and are culled on farm, resulting in enormous losses. This study tested the hypothesis that dietary supplementation with glycine enhanced the growth of IUGR pigs after weaning. Healthy pigs [14 IUGR pigs (birth weight = 0.98±0.03 kg, mean ± SEM) and 20 NBW pigs (birth weight = 1.44±0.02 kg, mean ± SEM)] were used for the trial. At weaning (21 d of age), pigs within each birth weight group were assigned randomly into corn- and soybean meal-based diets supplemented with 1% glycine plus 0.19% corn starch or 1.19% alanine (isonitrogenous control). There were 7 IUGR pigs and 10 NBW pigs per subgroup. Crude protein content in basal diets was 20% between d 21 and 64, 18% between d 65 and 108, and 16% between d 109 and 120 of age. During the 100-d period of feeding, feed intake per kg body weight did not differ (P &gt; 0.05) between IUGR and NBW pigs or between control and glycine groups. Growth rates of NBW pigs supplemented with 1% glycine did not differ (P &gt; 0.05) from those for NBW pigs without glycine supplementation. In contrast, growth rates of IUGR pigs supplemented with 1% glycine were 28%, 15%, and 10% greater (P &gt; 0.05) than those for IUGR pigs without glycine supplementation during d 21–35, d 35–64, and d 65–120 of age, respectively. Growth rates of NBW pigs were greater (P &gt; 0.05) than those for IUGR pigs without glycine supplementation during any experimental period. By d 120 of age, the body weight of IUGR pigs with glycine supplementation did not differ (P &gt; 0.05) from that of NBW pigs. Collectively, our results indicate that dietary supplementation with 1% glycine (a low-cost supplement) beneficially improves their growth rate and economic returns. Supported by a USDA/NIFA grant.


2011 ◽  
Vol 59 (2) ◽  
pp. 165-174 ◽  
Author(s):  
Ákos Thuma ◽  
Ádám Dán ◽  
Éva Kaszanyitzky ◽  
Béla Fazekas ◽  
Ádám Tóth ◽  
...  

Two groups of one-day-old Peking ducklings (Groups I and II, 12 birds/group) were inoculated orally withBrachyspira pilosicoliand two groups withB. alvinipulli(Groups III and IV, 12 birds/group). T-2 toxin was added to the feed of Groups II and IV in a dose of 1 mg/kg of feed. Groups V and VI served as uninfected control groups (ducks of Group VI received T-2 toxin). The body weight gain of the ducks was measured and clinical signs were monitored continuously. The birds were sacrificed and necropsied on days 7, 14, 21, and 28 post infection (PI). The liver, spleen, kidney, thymus, bursa of Fabricius, ileum, caecum and colon were examined histologically. Culturing ofBrachyspiraspp. and immunohistochemistry were performed from the sampled parts of the intestines as well. No gross pathological or histological lesions that could be associated withB. pilosicoliorB. alvinipulliwere detectable in the intestinal mucous membrane including the colonised intestinal glands. Mortality did not occur during the experimental period. Decrease in body weight gain was significant in the T-2-toxin-treated groups, and it was slight (not significant) in theBrachyspira-infected groups. Crust on the beaks, necrosis, crusting and ulceration in the mucous membrane of the oral cavity and on the skin of the feet, atrophy of the thymus and bursa of Fabricius due to the effect of T-2 toxin, accompanied by lymphocyte depletion, were observed. These lesions were most prominent on days 14 and 21 PI but were seen on day 28 PI as well. Immunohistochemical detection and reisolation ofB. pilosicoliandB. alvinipulliwere successful on days 7, 14, 21 and 28 days from different segments of the intestine of certain birds, but no significant difference was observed in the colonisation rate between the T-2-toxin-treated and the untreated groups.


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