scholarly journals Симптомокопмлекс за надгострого, гострого та підгострого перебігу пастерельозно-аскаридіозної асоціації у птиці різних видів

2017 ◽  
Vol 19 (77) ◽  
pp. 174-178
Author(s):  
V.M. Plys
Keyword(s):  
Pasteurella Multocida ◽  
Clinical Symptoms ◽  
Physiological State ◽  
Clinical Signs ◽  
The Body ◽  
Adult Bird ◽  
Shortness Of Breath ◽  
Ascaridia Galli ◽  
Acute Form ◽  
External Stimuli

Results of clinical display in poultry, the mixed pasteurellosis and ascaridosis, for 2014–2015 years. Clinical symptoms depend on the physiological state of the birds, feeding and the conditions, the virulence of the pathogen pasteurellosi, the cycle of the ascarides, the intensity of lesions ascarides, temperature and humidity of the external environment, sources and pathways of disease pathogens into the body of the bird. Usually acute form mixed of the disease ran without apparent clinical signs. Externally clinically healthy birds suddenly falls and dies, but some of the bird have noted clinical manifestation. Found that the birds by acute course mixed of disease were following clinical features: chicken – feathers ruffled, depression, fever, cyanosis of the crest and earrings, and before the death of noted a convulsive phenomena; waterfowl – depression, poor motility, fever, sometimes convulsions; in young birds – slow reaction to external stimuli, depression, convulsive muscle contractions; pigeons – ruffled feathers, refusal of reception food and water fever; parrots – depression, slow response to external stimuli, laxatives phenomena, litter gray with lots of transparent mucus and red speckled inclusions. Common signs of poultry on an acute disease were: young – poor motility, depression, anorexia, rhinitis, feathers ruffled, thirst, fever, anemia, are omitted wings, profuse diarrhea, shortness of breath, conjunctivitis, swelling of the joints; an adult bird - with beak and nostrils stands out sero-mucous fluid, ruffled feathers, diarrhea, dehydration of an organism, shortness of breath, appetite is not, visible mucous membranes pale, thickened joints, hot, limping. Over the course of subacute forms of the mixed pasteurellosis and ascaridosis, clinical symptoms were the same as in the acute form, but they less pronounced as the disease ran for several days or even weeks. The bird noted profuse diarrhea, shortness of breath, cyanosis earrings and combs, depression. Ascaridia galli in with Pasteurella multocida complicates the development and progress disease.

scholarly journals Diagnostic significance of clinical and para-clinical signs of community-acquired pneumonia in children

2020 ◽  
Vol 24 (2) ◽  
pp. 244-249
Author(s):  
V.Yu. Pasik
Keyword(s):  
Young Children ◽  
Sensitivity And Specificity ◽  
Clinical Symptoms ◽  
Clinical Signs ◽  
The Body ◽  
Diagnostic Methods ◽  
Statistical Hypothesis ◽  
Diagnostic Significance ◽  
Operational Characteristics ◽  
Gallbladder Dyskinesia

Annotation. Respiratory diseases are relevant in pediatric practice, which is associated with its widespread and frequent complications, especially in young children. The aim of the study was to assess the diagnostic value of clinical symptoms, laboratory and ultra-sonographic parameters in pneumonia in children of the first 3 years of life. A retrospective study of medical records of 218 children who were hospitalized in the department for young children diagnosed with pneumonia for the period from 2016 to 2018. The average age of children was 11.67±9.97 months and it was within the range from 1 month to 3 years. The ration of boys and girls was practically identical (51.8% and 48.2% accordingly). The first group included children aged under one year (the average age is 4.57±0.84 months; n=88). The second group included children aged from 1 to 3 years (the average age is 18.2±4.25 months; n=130). To characterize the information content of clinical and laboratory symptoms the study has used objective parameters defined as the operational characteristics of tests. The most important operational characteristics of diagnostic methods included: sensitivity (Se, sensitivity) and specificity (Sp, specificity). To check the statistical hypothesis on differences of absolute and relative frequencies, fractions, and ratios in two independent samples, the criteria of хі-square (χ2) was used. While detailing an anamnesis, the disease was more often related to untimely treatment and outpatient care. Various data were obtained on the absolute and relative risk, as well as the sensitivity and specificity of the localization of pneumonia depending on age. Therefore, the incidence of bilateral pneumonia was considered an indicator of risk. On admission to hospital, the body temperature of patients was 38.2±0.66°С. Most of the complaints were on the unproductive or productive cough. Besides, in some cases, shortness of breath and runny nose were mentioned. Thus, in young children with pneumonia, a diagnostically significant clinical symptom is a bilateral lung impression (82.6%), compared with right-handed (15.1%) and left-handed (2.3%), which is significantly more common in children under 1-th year of life compared with patients 1–3 years; laboratory features are probably higher levels of liver-specific enzymes – ALT and AST in children under 1 year; ultrasonographic indicators associated with the presence of pneumonia in young children include increased liver size, gallbladder deformity, the presence of sediment in the gallbladder, dyskinesia of the biliary tract, thickening of the gallbladder wall; children under 1 year of age have a risk of liver enlargement and biliary dyskinesia.

Arduino Promini-based Helmet Temperature Measuring Helmet with MLX90614-DCI Sensor

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Wahyu ja’far siddiq ◽  
Indah sulistiyowati
Keyword(s):  
Body Temperature ◽  
Clinical Symptoms ◽  
The Body ◽  
Shortness Of Breath ◽  
Turn On ◽  
Measurement Results ◽  
Accuracy Level ◽  
Human Body Temperature ◽  
Body Temperature Measurement ◽  
The Government

The Covid-19 pandemic that is currently spreading in Indonesia has claimed thousands of lives. Coronavirus Disease is characterized by the main clinical symptoms of fever >38 °C, coughing, to shortness of breath. In preventing its spread, the government conducts early detection by examining the main symptoms in the form of a fever and enforcing health protocols on each line. Therefore, we need an appropriate innovation that can make it easier for officers/guards to check human body temperature, especially in crowded places such as at airports, malls, or on the highway. Currently, body temperature measurement equipment is widely used, which allegedly made many errors in detecting it. Therefore, an innovative helmet was created that can be used by guards, security and even the police to detect body temperature based on the Arduino Pro Mini with the MLX90614-DCI sensor and the output is the real body temperature displayed on the LED screen. When the body temperature reads more than 38 °C, the helmet will turn on a buzzer and an LED to show that the target measurement is in a fever condition, and it is recommended going to the health center for further examination. This tool has been tested, and the sensor readings have an accuracy at a distance of 100 cm with several participants and the sensor readings are compared with the reading values from the alpha one thermometer and the measurement results have an accuracy level of 95%.

scholarly journals Tricuspid Dysplasia in Dogs

2013 ◽  
Vol 57 (1) ◽  
pp. 123-126 ◽  
Author(s):  
Urszula Pasławska ◽  
Agnieszka Noszczyk-Nowak ◽  
Adrian Janiszewski ◽  
Józef Nicpoń
Keyword(s):  
Clinical Symptoms ◽  
Heart Defects ◽  
Clinical Signs ◽  
The Body ◽  
German Shepherd ◽  
Ebstein Anomaly ◽  
German Shepherd Dog ◽  
Congenital Cardiac Disease ◽  
Cardiac Lesions ◽  
Estimate Prevalence

Abstract The aim of the study was to estimate prevalence of tricuspid dysplasia (TD) in dogs with respect to breed, age, sex, clinical signs, and echocardiographic findings and to compare this data with literature. TD was found in 15 dogs (6.5% of congenital cardiac disease) of 215 dogs with congenital heart defects. All dogs had right heart enlargement on thoracic radiographs, echocardiography, and electrocardiography. Doppler echocardiography revealed tricuspid valve regurgitation. Seven dogs presented no clinical symptoms to date. TD took the form of Ebstein anomaly in all Labrador Retrievers, one Boxer, and one German Shepherd dog. TD predominated in males (11 males vs. three females). The body weight of the affected dogs, with the exception of the Miniature Schnauzer, exceeded 20 kg. Two dogs (Boxer and Bull Terrier) had additional congenital cardiac lesions in the form of mitral valve dysplasia. The most affected breeds in the study were the Labrador Retriever and Boxer.

scholarly journals MILK LIPIDS AND SUBCLINICAL MASTITIS

2021 ◽  
Vol 15 (2) ◽  
Author(s):  
V. Danchuk ◽  
V. Ushkalov ◽  
S. Midyk ◽  
L. Vigovska ◽  
O. Danchuk ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Lipid Composition ◽  
Physiological State ◽  
Clinical Signs ◽  
Raw Milk ◽  
Subclinical Mastitis ◽  
The Body

This article deals with the process of obtaining quality raw milk by analyzing its lipid composition. The lipid composition of raw milk depends on many factors, among which, first of all, is the species, the composition of the diet and the physiological state of the breast. In recent years, a large amount of data has accumulated on the fluctuations of certain lipid parameters of milk depending on the type, age, lactation, diet, time of year, exercise, animal husbandry technology, physiological state of the lactating organism in general and breast status in particular. Factors of regulation of fatty acid composition of raw milk: genetically determined parameters of quality and safety; fatty acid composition of the diet; synthesis of fatty acids by microorganisms of the digestive tract; synthesis of fatty acids in the breast; physiological state of the breast. The milk of each species of productive animals has its own specific lipid profile and is used in the formulation of certain dairy products to obtain the planned technological and nutritional parameters. Diagnosis of productive animals for subclinical mastitis involves the use of auxiliary (thermometry, thermography, electrical conductivity) and laboratory research methods: counting the number of somatic cells; use of specialized tests; microbiological studies of milk; biochemical studies of milk. The biochemical component in the diagnosis of subclinical forms of mastitis is underestimated. An increase in body temperature implies an increase in the intensity of heat release during the oxidation of substrates, sometimes due to a decrease in the intensity of synthesis of energy-intensive compounds. There are simply no other sources of energy in the body. The situation is the same with certain parts of the metabolism, which are aimed at the development of protective reactions to the etiological factor aimed at the defeat of the breast. That is why the biochemical composition of breast secretions in the absence of clinical signs of mastitis undergoes biochemical changes and the task of scientists is to develop mechanisms for clear tracking of such changes, identification of animals with subclinical forms of mastitis and effective treatment.

scholarly journals Effect of Vitamin D3 On the Expression of Antimicrobial Peptide Gene in Experimental Pneumonia in Calf

2021 ◽  
Author(s):  
Parisa Asgharpour ◽  
Zohre Eftekhari ◽  
Mohammad Goli Nadealian ◽  
Gholam Reza Nikbakht Borojeni ◽  
Mohammad Reza Mokhber Dezfouli
Keyword(s):  
Vitamin D ◽  
Treatment Group ◽  
Vitamin D3 ◽  
Pasteurella Multocida ◽  
Mononuclear Cells ◽  
Clinical Symptoms ◽  
Clinical Signs ◽  
Cell Content ◽  
Peripheral Blood Mononuclear

Abstract Background Vitamin D3 has been identified as an immunomodulatory agent that confronts the pathogens via stimulating antimicrobial peptides (AMPs). Objective The effects of vitamin D3 on the expression of AMPs was assessed in experimental pasteurellosis in calves. Methods 10 Holstein crossbred male calves (2–4 months) were chosen and randomly divided into the two groups. Pasteurella multocida was prepared (3×109 CFU/mL) and inoculated in the trachea. Vitamin D3 was injected to the treatment group after confirming the pneumonia. Blood samples were obtained from both groups at different time intervals and the peripheral blood mononuclear cells (PBMCs) were isolated. Clinical symptoms were recorded. Broncho-alveolar lavage was performed to evaluate the lung cell content. On the other hand, 10− 6, 10− 7, and 10 − 8 molar (M) of vitamin D3, was used to evaluate the expression of CD4, BMAP34, and BNBD4 genes using PBMCs under the in vitro conditions. Results The prescription of vitamin D3 to the treatment group caused a decline in clinical signs. Following the vitamin D3 injections the treatment groups under the in vivo conditions, significant increase was observed in the expression level of Defensin (BNBD4), and CD4. Evaluation of bronchoalveolar lavage fluid (BALF) revealed that the amount of neutrophils decreased after vitamin D injection. In vitro, increased expression of Catalicidin (BMAP34), Defensin (BNBD4), and CD4 was observed at a concentration of 10− 6 M of vitamin D3. Conclusion The present study indicated that vitamin D3, exerts immunomodulatory effects on many infectious diseases via activation of VDR pathways and stimulation of AMP production.

scholarly journals Interactions between cardiac activity and conscious somatosensory perception

2019 ◽  
Author(s):  
Paweł Motyka ◽  
Martin Grund ◽  
Norman Forschack ◽  
Esra Al ◽  
Arno Villringer ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiac Cycle ◽  
Physiological State ◽  
Cardiac Activity ◽  
The Body ◽  
Cardiac Deceleration ◽  
Electrical Pulses ◽  
Somatosensory Stimuli ◽  
External Stimuli ◽  
Near Threshold

AbstractFluctuations in the heart’s activity can modulate the access of external stimuli to consciousness. The link between perceptual awareness and cardiac signals has been investigated mainly in the visual and auditory domain. We here investigated whether the phase of the cardiac cycle and the pre-stimulus heart rate influence conscious somatosensory perception. We also tested how conscious detection of somatosensory stimuli affects the heart rate. Electrocardiograms (ECG) of 33 healthy volunteers were recorded while applying near-threshold electrical pulses at a fixed intensity to the left index finger. Conscious detection was not uniformly distributed across the cardiac cycle but significantly higher in diastole than in systole. We found no evidence that the heart rate before a stimulus influenced its detection but hits (correctly detected somatosensory stimuli) led to a more pronounced cardiac deceleration than misses. Our findings demonstrate interactions between cardiac activity and conscious somatosensory perception, which highlights the importance of internal bodily states for sensory processing beyond the auditory and visual domain.Impact StatementIt is highly debated to what extent cardiac activity modulates the access of external stimuli to consciousness. The evidence is inconsistent across sensory modalities and previous research focused at specific intervals within the cardiac cycle. Here, we examined the perception of near-threshold electrical pulses across the entire cardiac cycle. Our results show that conscious somatosensory perception is enhanced during the late phase of the cardiac cycle (at diastole) and associated with a more pronounced cardiac deceleration (as compared to non-detected stimuli). This strengthens the evidence that the physiological state of the body influences how we perceive the world.

scholarly journals PECULIARITIES OF LIPID PEROXIDATION IN THE COW ORGANISM IN STRESS SYNDROME CAUSED BY EXTREMITIES

2020 ◽  
Author(s):  
А.В. МАТВЕЕВА ◽  
Э.О. САЙТХАНОВ
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Physiological State ◽  
Stress Hormones ◽  
Cholesterol Content ◽  
The Body ◽  
Diene Conjugates ◽  
Holstein Breed ◽  
Peroxidation Processes ◽  
External Stimuli

Цель исследований заключалось в изучении клинико-физиологического состояния и оценке интенсивности процессов перекисного окисления липидов у коров с патологиями конечностей в сравнении со здоровыми. Работа проводилась в СПК «Вышгородский» Рязанского района Рязанской области, мы проводили физикальное обследование для определения клинически здоровых коров и коров с заболеваниями конечностей. В контрольную и опытную группы включались коровы голштинской породы, массой 550-650 кг, 3-4-й лактации. В опытную группу 2 включались коровы с заболеваниями конечностей: язвы Рустергольца, абсцесса венчика, пальцевого пододерматита, гнойного пододерматита. Определяли продукты перекисного окисления: количество диеновых конъюгатов, малонового диальдегида, кетодиенов; определяли содержание холестерина в сыворотке крови. У коров с заболеваниями конечностей и находящихся в стрессовом состоянии в крови повышаются глюкокортикостеройды – гормон кортизол, вследствие этого запускается процесс перекисного окисления липидов (ПОЛ), что приводит к деградации гормонов стресса, и организм начинает усилено отвечать кортикотропной функцией гипофиза. В процессе перекисного окисления липидов накапливается значительное количество продуктов ПОЛ, у коров нарушается процесс глюкогенеза, нарушается гомеостаз. При патологических процессах, а именно при патологиях конечностей, возникает окислительный стресс в организме коров, который сопровождается процессами перекисного окисления липидов, что сопровождается повышением в крови количества конъюгированных диенов, кетодиенов, малонового диальдегида; на фоне повышения продуктов перекисного окисления снижается содержание холестерина у больных коров. При окислительном стрессе вследствие возникших патологических процессов конечностей у коров происходит изменение клинико-физиологических показателей: снижение активности, аппетита, реакции на внешние раздражители; повышается температура тела, частота пульса. The aim of the research was to study the clinical and physiological state and assess the intensity of lipid peroxidation processes in cows with limb pathologies in comparison with healthy ones.The work was carried out in the farm of the Ryazan region in the SEC "Vyshgorodsky" of the Ryazan region, we conducted a physical examination to determine clinically healthy cows and diseases of the limbs. The control and experimental groups included cows of the Holstein breed, weighing 550-650 kg, 3-4 lactations. The experimental group N2 included cows with diseases of the extremities: Rustergolts ulcer, corolla abscess, digital subdermatitis, purulent subdermatitis. Peroxidation products were determined, namely: the amount of diene conjugates, malondialdehyde, ketodienes, and serum cholesterol was also determined. Glucocorticosteroids, namely the cortisol hormone, increase in cows with limb diseases and in a stressed state, namely, the lipid peroxidation process, which leads to the degradation of stress hormones and the body begins to respond more intensely to the corticotropic function of the pituitary gland. In the process of lipid peroxidation, a signifi cant amount of lipid peroxidation products is accumulated, the process of glucogenesis is disrupted in cows, and homeostasis is disrupted. In pathological processes, namely in pathologies of the extremities, oxidative stress arises in the body of cows, which is accompanied by lipid peroxidation (LPO) processes, which is accompanied by an increase in the number of conjugated dienes, ketodienes, malondialdehyde in the blood, while cholesterol content decreases in the presence of increased peroxidation products sick cows. With oxidative stress due to the arising pathological processes of the limbs in cows, there is a change in clinical and physiological parameters, there is a decrease: activity of cows, appetite, reaction to external stimuli; rises: body temperature, pulse rate.

scholarly journals Risk Factors, Clinical Symptoms, Laboratory Findings and Imaging of Pregnant Women Infected with COVID-19 in North of Iran

2020 ◽  
Vol 23 (12) ◽  
pp. 856-863
Author(s):  
Soudabeh Kazemi Aski ◽  
Seyedeh Hajar Sharami ◽  
Fatemeh Hosseinzadeh ◽  
Ezat Hesni ◽  
Seyedeh Fatemeh Dalil Heirati ◽  
...  
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Viral Infections ◽  
Clinical Symptoms ◽  
Laboratory Finding ◽  
The Body ◽  
Shortness Of Breath ◽  
Laboratory Findings ◽  
Pregnancy And Childbirth ◽  
Severe Stage

Background: Due to the physiological changes in the body during pregnancy, the increased susceptibility to viral infections during this period and also the high prevalence of coronavirus disease 2019 (COVID-19) in the Guilan province, Iran, this study aimed to evaluate risk factors, clinical symptoms, laboratory findings and imaging of pregnant mothers with COVID-19. Methods: In this descriptive study, 70 pregnant women aged 17–41 years with COVID-19 who were hospitalized from early March to late April 2020 were enrolled. Sampling was performed by census and from all hospitals in Guilan. The research instruments included a researcher-made questionnaire, including demographic characteristics, clinical symptoms, medical examinations, and paraclinical results. Data were analyzed with SPSS version 16. Frequency and percent were used to describe qualitative variables; for quantitative variables, if they were normally distributed, mean and standard deviation were used, and if they were non-normal, median and interquartile range (IQR) were used. Results: The most severe symptoms recorded in mothers at the time of hospitalization were fever (47%), shortness of breath (16%) and cough (15%), respectively. One of 68 (1%) was in the severe stage of the disease and two mothers (2%) were in critical condition and admitted to the intensive care unit and finally died. Fifty-five of 66 women (83%) had lymphopenia, 22 of 42 (52%) tested positive on PCR, and 30 of 33 (90%) had an increase in lactate dehydrogenase (LDH) levels.Results showed that 15 of 32 patients who gave birth had preterm delivery (46%). Conclusion: The most common manifestations of the disease in pregnant women were fever, cough and shortness of breath, and in some cases muscle pain. The most common laboratory finding in infected mothers was lymphopenia. Complications of pregnancy and childbirth in women included an increase in cesarean delivery.

THE UPTAKE OF (6,7-3H) 17β-OESTRADIOL BY TISSUES OF THE DOMESTIC FOWL

1969 ◽  
Vol 60 (2) ◽  
pp. 199-209 ◽  
Author(s):  
R. A. Hawkins ◽  
P. J. Heald ◽  
Patricia Taylor
Keyword(s):  
Pituitary Gland ◽  
Intravenous Injection ◽  
Domestic Fowl ◽  
Physiological State ◽  
Laying Hen ◽  
Adult Bird

ABSTRACT A limited investigation of the distribution of radioactivity in the tissues of the adult laying hen has been made at differing times after intravenous injection of (6,7-3H) 17β-oestradiol. Uptake by all tissues examined was maximal between 2.0 and 4.0 minutes after injection. There was a marked retention of radioactivity by the oviduct and the liver. Of cerebral tissues examined the uptake of radioactivity was greatest in the pituitary gland. This uptake varied according to the physiological state of the bird. Calculations based on the rates of clearance of intravenous (6,7-3H) 17β-oestradiol indicate that in the adult bird the rate of secretion by the ovary is of the order of 1–2.0 mg oestradiol/24 h.

Prevalence of COVID-19-like Symptoms among People Living with HIV, and Using Antiretroviral Therapy for Prevention and Treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 373-380 ◽  
Author(s):  
SeyedAhmad SeyedAlinaghi ◽  
Maryam Ghadimi ◽  
Mahboubeh Hajiabdolbaghi ◽  
Mehrnaz Rasoolinejad ◽  
Ladan Abbasian ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Antiretroviral Treatment ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Shortness Of Breath ◽  
Sectional Study ◽  
Limited Data ◽  
Cross Sectional ◽  
Living With Hiv

Background: COVID-19 has spread globally with remarkable speed, and currently, there is limited data available exploring any aspect of the intersection between HIV and SARSCoV- 2 co-infection. Objective: To estimate the prevalence of clinical symptoms associated with COVID-19 among people living with HIV (PLWH) in Tehran, Iran. Design: Cross-sectional study. Methods: A total of 200 PLWH were recruited through the positive club via sampling, and completed the symptom-based questionnaire for COVID-19, which was delivered by trained peers. Results: Of 200 participants, respiratory symptoms, including cough, sputum, and shortness of breath, were the most prevalent among participants, but only one person developed symptoms collectively suggested COVID-19 and sought treatments. Conclusions: It appears that existing infection with HIV or receiving antiretroviral treatment (ART) might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms.

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