scholarly journals A végrehajtó funkciók összefüggése a testtömegindexszel és a DRD4-VNTR 7-es alléllal

2019 ◽  
Vol 160 (39) ◽  
pp. 1554-1562
Author(s):  
Julianna Bircher ◽  
Eszter Kótyuk ◽  
Renáta Cserjési ◽  
Andrea Vereczkei ◽  
Zsolt Rónai ◽  
...  

Abstract: Introduction and aim: Earlier results in the literature suggest that overweight subjects show weaker performance in executive function tasks as compared to normal weight people. Dopaminergic system is strongly linked to executive functions, body mass regulation and ingestion. The aim of the present study was to examine the possible relationship between DRD4 VNTR 7-repeat allele, body mass index and Stroop performance in a healthy adult population, and to draw psychogenetic conclusions. Method: 152 subjects without diabetic or psychiatric history participated in the study. Along with non-invasive DNA sampling, demographic, weight and height data were collected. The participants also solved the computerized Stroop task. 11 subjects belonged to the underweight (mean body mass index = 17.9 kg/m2), 98 subjects to the normal (mean body mass index = 21.8 kg/m2), and 43 subjects to the overweight (mean body mass index = 28.9 kg/m2) category. After grouping participants according to their body mass index and DRD4 VNTR genotype, we compared their mean performance to investigate the possible psychogenetic associations. Results: Body mass index and stimuli type showed significant interaction on error number (p = 0.045): subjects with normal body mass index made significantly less error as compared to under- and overweight subjects in incongruent trials. The 7-repeat allele carriers made tendentiously more errors than non-carriers. Normal weight people made less error – independently from their genotype –, while subjects with either low or high BMI carrying the 7-repeat allele made more errors compared to non-carriers. Conclusion: Under- and overweight subjects perform weaker where inhibition is necessary in the task. This may reflect their reactions to food-related situations. Orv Hetil. 2019; 160(39): 1554–1562.

2020 ◽  
Vol 17 (2) ◽  
pp. 164-170
Author(s):  
Nataliya N. Tyatenkova ◽  
Iuliya E. Uvarova

BACKGROUND: Obesity is one of the most common noncommunicable diseases. Overweight and obesity negatively affect all spheres of human activity, leading to the development of related diseases and disability. AIMS: to estimate the prevalence of overweight and obesity among the adult population of the Yaroslavl region according to sex and age. MATERIALS AND METHODS: The research included results of comprehensive medical examinations of 13948 persons of both sexes aged from 20 to 79 permanently residing in the Yaroslavl region. Anthropometric examination was performed by standard methods with the measurement of body weight and body length and calculation of body mass index. Overweight was defined as having a BMI to 25.029.9 kg/m2, obesity was defined as having BMI grater or equal to 30 kg/m2. The fat compound of body mass was determined by bioimpedancemetry. RESULTS: The prevalence of overweight among the adult population of the Yaroslavl region was 34.2%, obesity was 31.6%. Overweight in men of all ages was at least 1.5 times more prevalent than women, obesity in women was 1.3 times more prevalent than in men. The prevalence of firstdegree obesity was 20.9%, grade II and III 7.9% and 2.8%, respectively. The proportion of overweight and obesity increased with age, reaching a maximum of 5059 years for men and 6069 years for women. The gradient of age changes is more pronounced in women. Patients with normal body mass index had excessive fat deposition in 38% of cases. CONCLUSIONS: The study showed a high prevalence of overweight and obesity among adults in the Yaroslavl region.


Sports ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 103 ◽  
Author(s):  
Pantelis Nikolaidis ◽  
Eleni Kintziou ◽  
Georgios Georgoudis ◽  
José Afonso ◽  
Rodrigo Vancini ◽  
...  

Although the beneficial role of exercise for health is widely recognized, it is not clear to what extent the acute physiological responses (e.g., heart rate (HR) and oxygen uptake (VO2)) to a graded exercise test are influenced by nutritional status (i.e., overweight vs. normal-weight). Therefore, the main objectives of the present narrative review were to examine the effect of nutritional status on acute HR, and VO2 responses of children to exercise testing. For this purpose, we examined existing literature using PubMed, ISI, Scopus, and Google Scholar search engines. Compared with their normal-body mass index (BMI) peers, a trend of higher HRrest, higher HR during submaximal exercise testing, and lower HRmax was observed among overweight and obese children (according to BMI). Independent from exercise mode (walking, running, cycling, or stepping), exercise testing was metabolically more demanding (i.e., higher VO2) for obese and overweight children than for their normal-weight peers. Considering these cardiometabolic differences according to BMI in children might help exercise specialists to evaluate the outcome of a graded exercise test (GXT) (e.g., VO2max, HRmax) and to prescribe optimal exercise intensity in the context of development of exercise programs for the management of body mass.


2019 ◽  
Vol 11 (1) ◽  
pp. 1-8
Author(s):  
S Naher ◽  
SS Sejooti ◽  
MM Hoque ◽  
MS Zaman ◽  
H Imam ◽  
...  

Obesity has become a global epidemic and has been found to be associated with numerous comorbidities. Body mass index (BMI) based classification of obesity is simple but co-morbidities do not affect all obese and overweight people. The present study was aimed to find out the frequency of metabolic phenotypes in different BMI groups using metabolic syndrome (MetS) criteria and cardiometabolic disabilities (CA) criteria and also to find out an appropriate method for defining metabolic health among adult population attending out patient department of Bangabandhu Sheikh Mujib Medical University (BSMMU). This cross-sectional analytical study was carried out in the Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU) from March 2016 to February 2017. By non probability sampling, a total of 1023 study subjects were selected from apparently healthy adult individuals attending outpatient department of BSMMU. The study subjects were grouped into three body mass index classes and also further categorized into six groups according to metabolically unhealthy or healthy phenotypes by presence or absence of metabolic syndrome (MetS) criteria as well as cardiometabolic disabilities (CA) criteria respectively. Then agreement among different metabolic phenotypes based on these two criteria were observed. Frequency of different metabolic phenotypes i,e metabolically healthy normal weight (MHNW), metabolically obese normal weight (MONW), metabolically healthy over weight (MHOW), metabolically obese over weight (MOOW), metabolically healthy obese (MHO) and metabolically unhealthy obese (MUO) were 12.3%, 6.9%, 21.4%, 27.7%, 7.7%, 23.9% by MetS criteria and 7.7%, 11.5%, 11.6%, 37.4%, 6.1%, 25.6% by CA criteria respectively. MOOW followed by MUO were found to be predominant among all phenotypes. Fare agreement was found between two criteria in case of normal weight and overweight groups and good agreement was found in case of obese groups. From this study, it may be concluded that, attention should be given to the metabolically obese phenotypes in different BMI classes to reduce co-morbidities. Bangladesh J Med Biochem 2018; 11(1): 1-8


2019 ◽  
Vol 26 (11) ◽  
pp. 1958-1964
Author(s):  
Salem Ullah Abro ◽  
Quratulain Saleem ◽  
Muhammad Rizwan ◽  
Erum Aamir ◽  
Saleh Soomro ◽  
...  

The Obesity and Hypertension are major risk factors of several life threatening diseases in human body. Objectives: To determine correlation coefficient of Body Mass Index with blood pressure: a gender based comparison in medical students. Study Design: Comparative Cross-sectional study in students. Setting: Physiology department of BMU Karachi. Period: Duration of this study was 6 months from February 2017 to August 2017. Material and Methods: A total of 500 students were enrolled in this study. The anthropometric measurement [height (m2) and weight (kg)] was recorded for calculation of the Body Mass Index (BMI) and blood pressure (BP) was measured by using sphygmomanometer with stethoscope. SPSS version 22.0 was used to analyze the data. Results: BMI overall in both genders were significantly (p<0.05) correlated in mean Systolic Blood Pressure (SBP) and mean Diastolic Blood Pressure (DBP). Underweight and Normal weight were not correlated with both mean SBP and mean DBP in both genders. Overweight subjects were positively correlated with mean DBP in males and mean SBP in females (p<0.05). Obese students were not significantly (p>0.05) correlated with both mean SBP and mean DBP in males whereas, there were not enough observations to draw any meaningful conclusion in females. Conclusion: Overweight subjects were positively correlated (p<0.05) with mean DBP in males and mean SBP in females and overall BMI (mean SBP & mean DBP) in both genders.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
D. Nugmanova ◽  
Y. Feshchenko ◽  
L. Iashyna ◽  
M. Polianska ◽  
K. Malynovska ◽  
...  

Abstract Background The overweight/obese population (evaluated by a body mass index, BMI) represents a global health problem and contributes to the development of various chronic diseases. In this epidemiological study we evaluated this relationship by analyzing patient-reported questionnaires related to respiratory function, physical activity and BMI. Methods In 2013–2015, adult residents of selected cities were enrolled to this study in: Ukraine (M/F: 403/561), Kazakhstan (M/F = 348/597) and Azerbaijan (M/F: 389/544). Height was measured using a vertical measuring board, and body weight was measured by using portable digital scales. All participants were interviewed using CAT™, mMRC scale and IPAQ; respondents who also reported wheezing or whistling chest sounds during the previous 12 months additionally ACT™. Results 45.4% of respondents in Ukraine, 47.6% in Kazakhstan and 54.9% of respondents in Azerbaijan were found to be overweight/obese (BMI ≥ 25 kg/m2). The mean CAT™ total score among this population versus those respondents with a normal weight was 5.2 versus 3.6 (Ukraine, p < 0.001), 4.2 versus 2.9 (Kazakhstan, p < 0.001) and 5.9 versus 4.3 (Azerbaijan, p < 0.001). The number of respondents without airflow limitations (mMRC score 0) among overweight/obese respondents versus normal weight respondents was 298 (68.2%) versus 456 (86.7%) in Ukraine, 261 (58.1%) versus 387 (78.2%) in Kazakhstan and 343 (67.1%) versus 345 (82.3%) in Azerbaijan. The ACT™ total score between overweight/obese respondents and normal weight respondents was not statistically different. IPAQ showed a tendency towards a higher proportion of “low activity” results (compared to “moderate” and “high”) in the overweight/obese subgroup (24.7% vs. 23.8% in Kazakhstan, 18.5% vs. 14.6% in Azerbaijan), and in Ukraine this difference was significant (12.4% vs. 5.2%, p < 0.001). Conclusion CAT™ and mMRC are widely used tools for respiratory function assessment. Despite CAT™ scores being close to a normal value (< 5), the relationship of both CAT™ and mMRC scores with being overweight/obese was demonstrated in the general adult population of three CIS countries. IPAQ may also be a useful instrument for measuring activity level however, more objective studies are required to evaluate the relationship between BMI and physical activity.


2021 ◽  
Author(s):  
Qiang Li ◽  
Wen-yu Feng ◽  
Xiang-dong Li ◽  
Juan Li ◽  
Yuan Shen ◽  
...  

Abstract Background: Defined by normal body mass index (BMI) and higher waist-to-height ratio, normal weight with central obesity (NWCO) has been recognised as a risk factor for cardio-metabolic diseases. The study aims to estimate the prevalence of NWCO and to examine the relationship between NWCO and cardiovascular disease risk factors in adults of Shaanxi Province.Methods: A population-based cross-sectional survey was conducted among residents who were aged 18–80 years and had been living in Zhenba County, Shaanxi Province, for over six months in 2018. The multistage stratified cluster sampling method was used to enroll the study participants. Six towns (districts) in Zhenba County, Shaanxi Province, were randomly selected, and then six villages (communities) were randomly selected from each town (district). All residents in the villages (communities) were face-to-face interviewed. Descriptive data analysis and 95% confidence intervals (CIs) of prevalence/frequency were conducted. Logistic regression analyses were used to detect the corresponding factors associated with central obesity. Results: A total of 2312 participants (936 men and 1376 women) were analyzed. The prevalence of NWCO was 58.3%. NWCO was significantly associated with hypertension and dyslipidemia. Compared with normal weight non-central obesity (NWNO), the adjusted odds ratios (ORs) for hypertension were 1.47, (95% CI 1.10–1.98) in men and 1.55(1.14–2.10) in women, and the corresponding ones for dyslipidemia were 2.71 (1.77–4.13) in men and 1.84 (1.29–2.61) in women. Female sex, age over 58 years, and lower education level were also significantly predictors of abdominal obesity. In males, comparison with no cigarette smoking, daily cigarette smoking was less likely to lead to normal weight central obesity. Conclusion: In people with normal BMI, the prevalence of central obesity was 58.3%. Female, age over 58 years, hypertension and dyslipidemia indicate a higher risk. Body mass index alone as a measure of obesity is not enough to assess health risks. Central obesity index should be used together for clinical assessment.


2020 ◽  
Vol 4 (2) ◽  
pp. 38
Author(s):  
Khizqil Baharudin Akbar ◽  
Yoga Saputra ◽  
Windra Windra ◽  
Hengki Hartatadi

The results of this study indicate that there is a relationship between body mass index and body weight. The relationship between habits or lifestyle with weight is very influential. This happens because the average research subject does not regulate a healthy lifestyle. In this study, 54 students were selected as research subjects consisting of 42 male subjects and 12 female subjects. Most of the subjects in this study had nutritional status that showed a body mass index in the normal weight category of 25 people, overweight subjects as much as 8 people, underweight subjects as many as 6 people, and obese weight subjects as many as 6 people.


Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1657
Author(s):  
Adela-Viviana Sitar-Tǎut ◽  
Angela Cozma ◽  
Adriana Fodor ◽  
Sorina-Cezara Coste ◽  
Olga Hilda Orasan ◽  
...  

Currently, adipose tissue is considered an endocrine organ, however, there are still many questions regarding the roles of adipokines—leptin and ghrelin being two adipokines. The purpose of the study was to assess the relationship between the adipokines and their ratio with obesity and diabetes. Methods: Sixty patients (mean age 61.88 ± 10.08) were evaluated. Cardiovascular risk factors, leptin, ghrelin, and insulin resistance score values were assessed. The patients were classified according to their body mass index (BMI) as normal weight, overweight, and obese. Results: 20% normal weight, 51.7% overweight, 28.3% obese, and 23.3% diabetic. Obese patients had higher leptin values (in obese 34,360 pg/mL vs. overweight 18,000 pg/mL vs. normal weight 14,350 pg/mL, p = 0.0049) and leptin/ghrelin ratio (1055 ± 641 vs. 771.36 ± 921 vs. 370.7 ± 257, p = 0.0228). Stratifying the analyses according to the presence of obesity and patients’ gender, differences were found for leptin (p = 0.0020 in women, p = 0.0055 in men) and leptin/ghrelin ratio (p = 0.048 in women, p = 0.004 in men). Mean leptin/BMI and leptin/ghrelin/BMI ratios were significantly higher, and the ghrelin/BMI ratio was significantly lower in obese and diabetic patients. In conclusion, obesity and diabetes are associated with changes not only in the total amount but also in the level of adipokines/kg/m2. Changes appear even in overweight subjects, offering a basis for early intervention in diabetic and obese patients.


2020 ◽  
Vol 15 (45) ◽  

The objective of the study was to compare and relate motor behavior in relation to body mass index (BMI) and sex in children aged 6 to 10 years in Viña del Mar, Chile. 221 students participated (girls, n=102; boys, n=119) with an average age of 7.55 ± 1.31 years. Motor behavior was determined and classified with the Test of Gross Motor Development (TGMD-2). The body mass index (BMI) was calculated based on the ratio between weight and height (expressed in W/H2). The nutritional status was determined using the indicators of the Ministry of Health of Chile, which are based on international standards for nutritional evaluation of children and adolescents from 5 to 19 years of age. For result analyses, the sample was divided into two groups (low-normal-weight and overweight-obese) with a confidence interval of 95% (p < 0.05) for comparison between the groups. It was shown that low and normal body mass index boys had better locomotion (p = 0.026) and object control (p = 0.045) in relation to overweight and obese boys. The female sex presented no differences between groups. Amongst boys, BMI is negatively related to motor quotient (p = 0.001), while in girls, no relationship was observed. In terms of gross motor development, low-weight and normal-weight boys are more likely to have a better gross motor development than overweight and obese boys, though not the case in girls. It is concluded that overweight and obese boys have a lower motor skill than normal and low boys.


2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Miranti Kumesan ◽  
Diana Purwanto ◽  
Yanti Mewo

Abstract: In Indonesia, the incidence of degenerative disease has been raising. The main contributors to the degenerative disease are unhealthy modern lifestyle, smoking habit, drinking alcohol, irregularly diet and less physical activity. Blood triacylglycerol level is also a risk factor for degenerative disease. Body mass index (BMI) has a correlation with blood triacylglycerol level. A normal body mass index also has a normal mean of blood triacylglycerol level. The purpose of this study is to find out the blood triacylglycerol level in students year 2011 Medical Faculty of Sam Ratulangi University with body mass index 18,5-22,9 kg/m2. This study was a descriptive study with cross sectional design. The sample was taken with purposive method sampling. There were 31 participants on this study. The result of this study was 31 participants had normal blood triacylglycerol level. Conclusion: The blood triacylglycerol level in students year 2011 Medical Faculty of Sam Ratulangi University with body mass index 18,5-22,9 kg/m2 is normal. Keywords: BMI, triacylglycerol.     Abstrak: Di Indonesia telah terjadi peningkatan kejadian penyakit degeneratif. Kontributor utama terjadinya penyakit degeneratif ialah gaya hidup modern yang tidak sehat seperti kebiasaan merokok, minum alkohol, pola makan yang tidak teratur dan aktivitas fisik yang kurang. Kadar triasilgliserol dalam darah juga merupakan faktor risiko terjadinya berbagai penyakit degeneratif. Indeks massa tubuh (IMT) memiliki korelasi bermakna dengan kadar triasilgliserol darah. Pada indeks massa tubuh normal, rata-rata kadar triasilgliserol darah juga normal. Tujuan penelitian ini ialah untuk mengetahui gambaran kadar triasilgliserol darah mahasiswa angkatan 2011 Fakultas Kedokteran Unsrat dengan indeks massa tubuh 18,5-22,9 kg/m2. Penelitian ini merupakan penelitian deskriptif dengan desain cross sectional. Pengambilan sampel dengan metode purposive sampling. Jumlah responden dalam penelitian ini 31 orang. Pada penelitian ini diperoleh hasil 31 responden memiliki kadar triasilgliserol normal. Simpulan: Gambaran kadar triasilgliserol darah mahasiswa angkatan 2011 Fakultas Kedokteran Unsrat dengan indeks massa tubuh 18,5-22,9 kg/m2 ialah normal. Kata kunci: IMT, triasilgliserol.


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