scholarly journals Psoriasis and uveitis: a literature review

2012 ◽  
Vol 87 (6) ◽  
pp. 877-883 ◽  
Author(s):  
Naiara Abreu de Azevedo Fraga ◽  
Maria de Fátima Paim de Oliveira ◽  
Ivonise Follador ◽  
Bruno de Oliveira Rocha ◽  
Vitória Regina Rêgo
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
Vision Loss ◽  
Intraocular Inflammation ◽  
Joint Involvement ◽  
World Population ◽  
Adequate Treatment ◽  
Immune Mediated ◽  
The World ◽  
Inflammatory Drugs

Psoriasis is a systemic, chronic, immunologically mediated disease, with significant genetic and environmental influences. It affects from 1 to 3% of the world population. Recently, the relation between psoriasis and different comorbidities, particularly metabolic syndrome, has become extremely relevant. Uveitis is characterized by a process of intraocular inflammation resulting from various causes. Considering psoriasis and uveitis as immune-mediated diseases, this study aims to evaluate the possible association of psoriasis and/or psoriatic arthritis with uveitis and its subtypes. Few studies have evaluated the association of uveitis and psoriasis without joint involvement. It seems that psoriasis without arthropathy is not a risk factor for the development of uveitis. Uveitis tends to develop more frequently in patients with arthropathy or pustular psoriasis than in patients with other forms of psoriasis. Ophthalmic examination should be performed periodically in patients with psoriasis and uveitis. If ophthalmopathy is diagnosed, the patient should receive adequate treatment with anti-inflammatory drugs or immunomodulators to prevent vision loss.

scholarly journals Metabolic syndrome and heart failure: mechanism and management

2021 ◽  
Author(s):  
Sidhi Laksono Purwowiyoto ◽  
Ananta Siddhi Prawara
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
World Population ◽  
Neurohormonal Activation ◽  
Comprehensive Management ◽  
The World ◽  
Current Guidelines ◽  
Careful Management

Heart failure (HF) and metabolic syndrome (MetS) are syndromes that affect a large proportion of the world population. MetS is known to be one of the risk factors of HF, and it can also act as comorbidity in HF. This review aims to further discuss the mechanism of MetS in causing HF, the management of MetS in order to prevent HF, and the management of MetS in HF patients. Visceral adiposity is the primary trigger of MetS which is followed by chronic inflammation, insulin resistance, and neurohormonal activation. All the mechanisms causing MetS play also an important role in the progression of HF. The MetS approach can be achieved by managing its components according to the current guidelines and careful management of MetS should be done in patients with HF. MetS is closely related to the progression of HF so that comprehensive management which involves a multidisciplinary team is necessary for managing patients with metabolic syndrome and heart failure.

scholarly journals Effect of menopausal hormone therapy on components of the metabolic syndrome

2016 ◽  
Vol 11 (1) ◽  
pp. 33-43 ◽  
Author(s):  
Dragana Lovre ◽  
Sarah H. Lindsey ◽  
Franck Mauvais-Jarvis
Keyword(s):  
Metabolic Syndrome ◽  
Hormone Therapy ◽  
Visceral Obesity ◽  
Menopausal Hormone Therapy ◽  
World Population ◽  
Metabolic Function ◽  
Metabolic Dysfunction ◽  
The Metabolic Syndrome ◽  
The World

The world population is aging, and women will spend an increasing share of their lives in a postmenopausal state that predisposes to metabolic dysfunction. Thus, the prevalence of metabolic syndrome (MetS) in women is likely to increase dramatically. This article summarizes the effects of menopause in predisposing to components of MetS including visceral obesity, dyslipidemia, type 2 diabetes (T2D) and hypertension (HTN). We also summarize the effects of menopausal hormone therapy (MHT) in reversing these metabolic alterations and discuss therapeutic advances of novel menopausal treatment on metabolic function.

scholarly journals Cutaneous and Systemic Psoriasis: Classifications and Classification for the Distinction

2021 ◽  
Vol 8 ◽  
Author(s):  
Bing-Xi Yan ◽  
Xue-Yan Chen ◽  
Li-Ran Ye ◽  
Jia-Qi Chen ◽  
Min Zheng ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Psoriatic Arthritis ◽  
Inflammatory Disease ◽  
Bowel Disease ◽  
Cutaneous Manifestation ◽  
Brain Diseases ◽  
World Population ◽  
The World ◽  
Erythematous Plaques

Psoriasis is a chronic multisystem inflammatory disease that affects ~0.1–1.5% of the world population. The classic cutaneous manifestation of psoriasis is scaly erythematous plaques, limited or widely distributed. Moreover, psoriasis could be associated with comorbidities like psoriatic arthritis, metabolic syndrome, diabetes, cardiovascular disease, nephropathy, bowel disease, and brain diseases. In this review, we suggest that psoriasis should be classified as cutaneous psoriasis or systemic psoriasis and propose the classification for distinction. This would help to better understand and manage psoriasis.

scholarly journals Observational and Comparative Study of Utility of Transabdominal Ultrasound in Diagnosis of Mild Acute Gastritis

2020 ◽  
pp. 5-12
Author(s):  
Dr. Vikas Leelavati Balasaheb Jadhav ◽  
Dr. S. G. Gandage ◽  
Dr. Sanjay M. Khaladkar ◽  
Dr. Rajesh S. Kuber
Keyword(s):  
Imaging Modality ◽  
Stomach Wall ◽  
World Population ◽  
Transabdominal Ultrasound ◽  
Extreme Stress ◽  
Normal Individuals ◽  
The World ◽  
Acute Gastritis ◽  
Inflammatory Drugs

Background: Inflammation of the gastric mucosa is gastritis. It may be acute or chronic. It usually affects half of the world population. Acute gastritis is caused by medications, like, NSAID (Nonsteroidal Anti-Inflammatory Drugs) and Corticosteroids, viral infection, extreme stress, etc. Aim and Objectives: To assess/evaluate the role of transabdominal ultrasound as an imaging modality for the diagnosis of acute gastritis and to study patterns of involvement of various layers of the stomach wall. Materials and Methods: The thickness of the whole Stomach wall and individual layers were calculated in 20 normal individuals (Control) and 20 Patients of Gastritis, confirmed later on Endoscopy. Endoscopy was performed on the same or the next day after the Sonography.

scholarly journals Prevalence of carotid artery disease in patients with metabolic syndrome

2020 ◽  
Vol 12 ◽  
Author(s):  
Tatjana Deleva-Stoshevska
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
Carotid Artery ◽  
Carotid Artery Disease ◽  
Significant Risk ◽  
Adequate Treatment ◽  
Effective Prevention ◽  
Linear Probe ◽  
Artery Disease ◽  
The Impact

There is a growing body of scientific evidence on the impact of metabolic syndrome (MetS) on the progression of atherosclerosis, imposing the need for research of the association of MetS with carotid artery disease (CAD) as a significant risk factor for cerebrovascular insult (CVI) and transient ischemic attack (TIA). The aim of the study was to determine the prevalence of CAD as a risk factor for CVI and TIA in subjects with MetS. Material and methods: A cross-sectional study was performed including a total of 118 subjects, 65 men, 53 women, with MetS according to NCEP ATP III criteria that were analyzed clinically, biochemically and ultrasonographically in the City General Hospital "8th September" - Skopje in the period from January 2017 to January 2018. Waist circumference, blood pressure, glycemia, triglycerides, and HDL cholesterol were determined according to standard routine protocols. The evaluation of the extracranial carotid trunk was done with a Color Doppler Duplex sonography with a linear probe of 7.5MHz. CAD assessment was performed using Ultrasound Consensus Criteria for Carotid Stenosis. An objective neurological assessment of the existence of CVI and TIA was performed by a standard protocol for neurological examination and brain CT results from medical history were reviewed. Results: The prevalence of CAD in this study was 77 subjects (65.25%), of which 35 subjects (29.66%) had symptomatic CAD, 17 subjects (48.57%) had CVI, 18 subjects (51.43%) had TIA. Regarding the degree of carotid artery stenosis (CAS) in the total number of subjects with MetS and CAD, no subjects with normal findings were registered, 16 subjects had stenosis <50% , 29 subjects had stenosis 50-69% , 23 subjects had stenosis 70-99% , while 9 subjects had occlusion. Conclusion: The results obtained in this study have shown that asymptomatic CAD is dominant in patients with MetS, which further imposed the need for timely extracranial ultrasonographic evaluation of the carotid trunk. This would achieve both effective prevention and adequate treatment of CVI and TIA, thereby reducing morbidity and mortality from cerebrovascular events which has a great health and socioeconomic significance.

Suicide Prevention Strategies: An Overview

2021 ◽  
pp. 447-448
Author(s):  
Veerabhadrappa G. Mendagudli ◽  
Shivaleela S. Sarawad
Keyword(s):  
Risk Factor ◽  
General Population ◽  
Cause Of Death ◽  
Suicide Rate ◽  
Tamil Nadu ◽  
Large Population ◽  
Significant Risk ◽  
World Population ◽  
Indian Government ◽  
The World

Suicide is the intentional self-infliction of death. It is a leading cause of death all over the world. Suicide is the third leading cause of death among teenagers aged 15 to 19. Low- and middle-income countries account for 79 % of global suicides. Pesticide ingestion, hanging, and weapons are among the most popular ways to commit suicide around the world. Suicides had increased to 230,314 in India in 2016. Suicide was the leading cause of death in both the 15–29 and 15–39 age groups. About 800,000 people die by suicide worldwide every year, of these 135,000 (17%) are residents of India, a nation with 17.5% of world population. A prior suicide attempt is the single most important risk factor for suicide in the general population. Every year, approximately 800,000 people die by suicide around the world, with 135,000 (17%) of them living in India, which accounts for 17.5% of the global population. For every suicide there are many more people who attempt suicide every year. In the general population, having attempted suicide previously is the single most significant risk factor for suicide. Tamil Nadu had the highest suicide rate of 12.5 percent in 2012, followed by Maharashtra (11.9 percent) and West Bengal (11.0 percent). Tamil Nadu and Kerala had the highest suicide rates per 100,000 people among large population states in 2012. In India, the ratio of male to female suicides is around 2:1. The number of suicides in India is estimated to be in the millions. For example, a study published in The Lancet predicted 187,000 suicides in India in 2010, although official data from the Indian government claims 134,600 suicides. According to WHO data, India's age-standardized suicide rate for women is 16.4 per 100,000 (6th highest in the world), and for men it is 25.8 per 100,000. (Ranking 22nd).

Ulcer Healing Potential of the Aqueous Extract of Malvastrum tricuspidate Eliminating Toxicity

2020 ◽  
Vol 9 (2) ◽  
pp. 27-30
Author(s):  
Vishal N. Kushare ◽  
Sagar V. Ghotekar ◽  
Manmeet S. Mandloi
Keyword(s):  
Food Habits ◽  
Antiulcer Activity ◽  
World Population ◽  
Standard Drug ◽  
Ulcer Disease ◽  
Plant Parts ◽  
The People ◽  
Stomach Pain ◽  
The World ◽  
Inflammatory Drugs

Ulcers are one of the dreadful and technically known as Peptic Ulcer Disease (PU Disease). Around 10million people around the world are suffering from the disease, and the majority of the people are about 20-50 years of age. This is not a dangerous disease on its own. Still, the ulcers are responsible for the resulting in other diseases like indigestion stomach pain etc. there are various reasons for the causation of ulcer. They are excessive use of pain killers and anti-inflammatory drugs, malnutrition, and unhealthy food habits, stress and steroids. Almost half of the world population relies on herbs for the treatment, and the major sources of the chemical leads that treat diseases are in the medicinal plants only. Many plants have been investigated and reported for their potential antiulcer benefits and are published too for that. The plant parts of Malvastrum tricuspidatum were extracted using distilled water and were investigated for the antiulcer activity in 3 doses like 100,200 and 400mg. The Extract at a higher dose showed better activity than other lower doses. The activity was compared with the standard drug and showed a significantly better activity that the standard and other doses of Extract too.

The demographic determinants of Africa’s changing global position

Human Affairs ◽  
2018 ◽  
Vol 28 (4) ◽  
pp. 367-378
Author(s):  
Valéria Bankóová
Keyword(s):  
Risk Factor ◽  
Potential Risk ◽  
Potential Risk Factor ◽  
World Population ◽  
African Development ◽  
The World ◽  
Economic Position ◽  
New Distribution ◽  
Demographic Growth

Abstract Demographic growth has in recent years been one of the determining characteristics of African development, and if projections are correct, the continent is set to become a population superpower. Its proportion of the world population, especially relative to the “old continent”, is increasing in a historically unprecedented manner, and its inhabitants are younger than ever. Although it is still difficult to assess whether this trend should be regarded as an opportunity or as a potential risk factor, it is already possible to discern the first definitive signs of how this evolving new distribution of demographic power is shifting Africa’s geopolitical and economic position in today’s polycentric world.

scholarly journals Pulmonary tuberculosis co-infection and COVID-19 in Senegal

2020 ◽  
pp. 1-4
Author(s):  
Agbogbenkou Tevi Déla-dem Lawson ◽  
◽  
Fulgence Abdou Faye ◽  
Adama Berthe ◽  
◽  
...  
Keyword(s):  
Risk Factor ◽  
Severe Acute Respiratory Syndrome ◽  
Pulmonary Tuberculosis ◽  
Potential Risk ◽  
Regional Hospital ◽  
Lung Damage ◽  
Treatment Center ◽  
Adequate Treatment ◽  
The World ◽  
Fragmented Data

New Coronavirus Disease (SARS-CoV-2) is responsible for the severe acute respiratory syndrome. Appeared in Wuhan, China, in December 2019, it affects more than 188 countries around the world to date. Africa is not spared by this pandemic (COVID-19), which is on the rise. Tuberculosis (TB), a disease endemic in Africa with a fatality of 1.5 million people per year , like COVID-19, is transmitted mainly by the respiratory route and affects the lungs[1,2]. In the literature, few studies have demonstrated the association and interactions between these two pathologies. However, the fragmented data reveal that tuberculosis with pulmonary localization must be considered as a potential risk factor for aggravation or complication of the disease. COVID-19, especially since the lung damage is significant, therefore In the fight against the COVID-19 pandemic, we must not forget to suspect and appropriately manage tuberculosis [2]. We report here the case of 3 patients who presented with COVID-19-Tuberculosis co-infection, treated at the level of the Epidemic Treatment Center (CTE) of the Thiès regional hospital in Senegal and whose evolution is favorable under early and adequate treatment.

Better Outcome in Laparoscopic Gastric Ulcer Perforation Than Laparotomy : Single Center Experience

2017 ◽  
Vol 2 (4) ◽  
Keyword(s):  
Helicobacter Pylori ◽  
Risk Factor ◽  
Gastric Ulcer ◽  
Seasonal Variation ◽  
Single Center ◽  
Ulcer Disease ◽  
Single Center Experience ◽  
The World ◽  
Inflammatory Drugs ◽  
H Pylori

Each year gastric ulcer disease (PUD) affects 4 million people around the world. Complications are encountered in 10%-20% of these patients and 2%-14% of the ulcers will perforate [1]. Females account for more than half the cases, they are older and have more comorbidity than their male counterparts. Main etiologic factors include use of non-steroidal anti-inflammatory drugs (NSAIDs), steroids, smoking, Helicobacter pylori (H. pylori) and a diet high in salt. All these factors have in common that they affect acid secretion in the gastric mucosa. Defining the exact etiological factor in any given patient may often be difficult, as more than one risk factor may be present and they tend to interact [2]. While previous reports have shown a seasonal variation in the incidence of PPU, others have failed to find such a pattern [3].

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