scholarly journals Associations between high levels of hostility and coronary heart disease in an open urban population among 25—64-year-old men

2017 ◽  
Vol 89 (1) ◽  
pp. 28-31 ◽  
Author(s):  
E V Akimova ◽  
M Yu Akimov ◽  
E I Gakova ◽  
M M Kayumova ◽  
V V Gafarov ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Epidemiological Survey ◽  
Survey Method ◽  
Male Population ◽  
Administrative District ◽  
Cross Sectional ◽  
Open Population ◽  
Epidemiological Surveys ◽  
Old Men

Aim. To establish the associations of the prevalence of coronary heart disease (CHD) with high levels of hostility in the open population of 25—64-year-old men in an average urbanized Siberian town. Subjects and methods. A cross-sectional epidemiological survey was conducted in a representative sample of the electorate of a Tyumen administrative district among 1000 males, with 250 being in each of 4 life decades (25—34, 35—44, 45—54, and 55—64 years). There were 850 (85%) responses. Different forms of CHD were identified by standard methods (the WHO exertional angina questionnaire, resting EEG, and Minnesota coding) used in epidemiological surveys. Definite CHD (DCHD) and possible CHD were identified. A continuous survey method was used by self-filling out the WHO MONICA-psychosocial questionnaire to estimate the levels of hostility. Results. In an average urbanized Siberian town, the prevalence of high levels of hostility among 25—64-year-old men was 46.4% (age-adjusted rate). The high levels of hostility increased with age, peaking in the 55—64-year-old group. In the Tyumen male population aged 25—64-year-old, the odds ratio (OR) for coronary heart disease and high levels of hostility was 2.71; 95% confidence interval (CI), 1.63—4.52 (p

scholarly journals Association of Fast Food Intake as a Risk Factor of Coronary Heart Disease in Male Population of Karachi, Pakistan

2020 ◽  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Food Intake ◽  
Fast Food ◽  
Dietary Habits ◽  
Strong Association ◽  
Sampling Technique ◽  
Middle Aged ◽  
Male Population ◽  
Cross Sectional

Objective: To determine the association of fast food intake and development of coronary heart disease with middle-aged men due to the nature of their job and eating habits. Methods: A cross-sectional study conducted among middle-aged males working in a different professional environment. The duration of the study was from March-October 2019. The calculated sample size was 385 and a Non-probability convenient sampling technique was used to collect data. Only Men aged 35-60 years of age working in different professional setups were included. Data was collected through a pre-structured questionnaire. Data was entered on IBM SPSS version 20. Results: The response rate to the survey was 85% while the completion rate of the survey was 94.5%. The mean age was 44.89 ±7.58 years having an average BMI of 25.94±3.89kg/m2. Out of these 311 men, 97.1% were a fast-food consumer. Fast food was more likely to be consumed by people who were doing a desk job than people whose nature was other than desk work (p=0.049). Among fast-food consumers, 40.7% had hypertension, 35.4% were obese, 22.5% had heart disease, and 21.9% had dyslipidemia. No significant association of heart disease (p=0.0689), obesity (p=1.00), hypertension (p=0.323) and dyslipidemia (p=0.213) was found with fast food consumption. Conclusion: Direct association between fast food and Coronary heart (CHD) disease is not significantly observed in the current study. However, dietary habits and the consumption of fast food have a profound effect on the development of predisposing factors of CHD. It is also concluded that long hours of desk job have a strong association with increased fast food intake due to its easy and quick availability within the short duration of time.

scholarly journals EPIDEMIOLOGICAL ASPECTS OF THE PREVALENCE OF CORONARY HEART DISEASE IN AN OPEN URBAN POPULATION: GENDER DIFFERENCES

2019 ◽  
Vol 34 (2) ◽  
pp. 146-151 ◽  
Author(s):  
M. M. Kayumova ◽  
E. I. Gakova ◽  
O. V. Senatorova
Keyword(s):  
Coronary Artery Disease ◽  
Gender Differences ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Artery ◽  
Urban Population ◽  
Epidemiological Methods ◽  
Administrative District ◽  
Open Population ◽  
Artery Disease

The aim. To determine gender differences in the prevalence of coronary heart disease in an open urban population.Material and Methods. For a one-stage epidemiological study in an open urban population, a representative sample of 25–64-year-old residents was formed from the electoral lists of the Central Administrative District of Tyumen (n=2000) using a “random” mathematical method. The response rates of the study were 85.0% among men and 70.3% among women. The conclusion about the presence of coronary artery disease was carried out according to strictly standardized epidemiological methods. Definite CHD (strict criteria) and possible CHD (lax criteria) were distinguished based on the extended criteria.Results. The prevalence rates of CHD in the open 25–64-year-old population were 12.4% in men and 10.0% in women. According to strict epidemiological criteria, the prevalence of painless ischemic heart disease prevailed in men; the prevalence of angina pectoris prevailed in women (predominantly at a young age). According to non-strict criteria, possible myocardial ischemia prevailed in men and women.Conclusion. The results can serve as a scientific basis for primary prevention of coronary artery disease and also necessitate identification of the gender differences in the study of the profile of conventional and non-conventional risk factors and their relationships with the prevalence of CHD in an open population of the urbanized Siberian city.

Hubungan Kadar Kolesterol Total Dan Hipertensi Dengan Kejadian Penyakit Jantung Koroner DI RSUD dr. Soedarso Pontianak

2018 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Laila Kamila ◽  
Maulidiyah Salim
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Total Cholesterol ◽  
Blood Vessels ◽  
Public Hospital ◽  
Sampling Technique ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Purposive Sampling

Abstract: Coronary heart is a disease that offense to blood vessels and heart attack due to constriction of blood vessels. A high level of cholesterol in blood or exceeds the normal limit can form sediment in wall of blodd vessels which cause blood vessels constriction or blockage. This research object to determine whether there is a correlation between cholesterol level total and hypertension with coronary heart disease in patients who hospitalized in Regional Public Hospital of dr. Soedarso Pontianak. This study was used cross sectional design, purposive sampling technique, it gained 50 people as samples. The measurement of blood pressure was done in heart poly and cholesterol total level in clinic laboratory of Regional Public Hospital of dr. Soedarso by using enzymatic CHOD-PAP method. It can be obtained that 10 people had hypertension and 40 people did not.the average of total cholesterol was 224 mg/dl. Maximum value of total cholesterol was 224 mg/dl and 152 mg/dl as minimum value. Data has been analyzed by using statistical test, Chi-Square, to determine the correlation of total cholesterol wit coronary heart disease, obtained p value=0,024 (less than α=0,05). Correlation of hypertension and coronary heart disease gained p value=0,923 (more than α=0,05), it can be concluded that total cholesterol correlated with coronary heart disease, and there was not a correlation between hypertension and coronary heart disease.Abstrak: Jantung koroner adalah penyakit yang  menyerang pembuluh darah dan serangan jantung, karena penyempitan pada pembuluh darah. Kadar kolesterol yang tinggi dalam darah melebihi normal dapat membentuk endapan pada dinding pembuluh darah sehingga menyebabkan penyempitan dan tersumbatnya pembuluh darah. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dan hipertensi dengan penyakit jantung koroner pada pasien di RSUD dr. Soedarso Pontianak. Disain penelitian  ini menggunakan cross sectional, teknik pengambilan sampel yaitu purposive sampling, didapat jumlah sampel 50 orang. Pengukuran Tensi Darah dilakukan di poli Jantung dan pemeriksaan kadar kolesterol total di laboratorium klinik RSUD dr. Soedarso Pontianak dengan metode enzimatik CHOD-PAP. Hasil penelitian didapatkan 10 orang mengalami hipertensi dan 40 orang non hipertensi. Rata-rata kadar kolesterol total 224 mg/ dl. Nilai maksimum kadar kolesterol total yaitu 224 mg/dl dan nilai minimum yaitu 152 mg/dl. Analisa data dengan uji statistik Chi-square untuk mengetahui hubungan kolesterol total dengan penyakit jantung koroner didapatkan nilai p = 0,024 (lebih kecil dari  α 0,05). Uji hubungan hipertensi dengan penyakit jantung koroner didapat nilai p = 0,923 (lebih besar dari α 0,05), dapat disimpulkan terdapat hubungan kadar kolesterol total dengan penyakit jantung koroner dan tidak ada hubungan hipertensi dengan penyakit jantung koroner.

scholarly journals Relationship between childhood secondhand smoke exposure and the occurrence of hyperlipidaemia and coronary heart disease among Chinese non-smoking women: a cross-sectional study

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e048590
Author(s):  
Kewei Wang ◽  
Yuanqi Wang ◽  
Ruxing Zhao ◽  
Lei Gong ◽  
Lingshu Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Secondhand Smoke ◽  
Chinese Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Shs Exposure

ObjectiveThe objective of this study was to evaluate the influence of secondhand smoke (SHS) exposure during childhood on type 2 diabetes mellitus, hypertension, hyperlipidaemia and coronary heart disease among Chinese non-smoking women.MethodsIn this cross-sectional study, the SHS exposure data in childhood were obtained using a questionnaire survey. Self-reported childhood SHS exposure was defined as the presence of at least one parent who smoked during childhood.ResultsOf the 6522 eligible participants, 2120 Chinese women who had never smoked were assessed. The prevalence of SHS exposure in the entire population was 28.1% (596). SHS exposure during childhood was not significant for the standard risk factors of type 2 diabetes mellitus (p=0.628) and hypertension (p=0.691). However, SHS was positively associated with hyperlipidaemia (p=0.037) after adjusting for age, obesity, education status, physical activity, alcohol consumption, current SHS exposure status, diabetes mellitus and hypertension. In addition, childhood SHS increased the occurrence of coronary heart disease (p=0.045) among non-smokers after further adjusting for hyperlipidaemia.ConclusionSHS exposure during childhood is associated with prevalent hyperlipidaemia and coronary heart disease in adulthood among non-smoking Chinese women.

scholarly journals Prediction of coronary heart disease incidence in a general male population by circulating non-coding small RNA sRNY1-5p in a nested case–control study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Vera L. Costa ◽  
Jean-Bernard Ruidavets ◽  
Vanina Bongard ◽  
Bertrand Perret ◽  
Emanuela Repetto ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Small Rna ◽  
Case Control Study ◽  
Disease Incidence ◽  
Case Control ◽  
Male Population ◽  
General Male Population ◽  
Nested Case Control ◽  
Control Study

AbstractDuring the development of atherosclerotic lesion, s-RNYs (small RNAs of about 24/34 nucleotides) are derived by the processing of long Ro-associated non-coding RNAs (RNYs) in macrophages. The levels of serum s-RNYs have been found significantly upregulated in patients with coronary heart disease (CHD) compared to age-matched CHD-free individuals. The present study aimed to examine the predictive value of serum s-RNYs for CHD events in the general male population. Within the frame of nested-case–control study, the GENES study, we measured the absolute expression of a RNY-derived small RNA, the s-RNY1-5p, in the serum of individuals (without CHD at baseline) who encountered a CHD event within 12 years of follow-up (n = 30) (Cases) and compared them to individuals who remained event-free (Controls) (n = 30). The expression of s-RNY1-5p in serum was significantly upregulated in Cases compared to Controls (p = 0.027). The proportion of CHD event-free was significantly higher among individuals with serum s-RNY1-5p below the median value (631 molecules/mL). In a multivariable model adjusted for age, smoking, hypertension, diabetes and dyslipidemia, the risk of CHD events increased more than fourfold in individuals with serum s-RNY1-5p above the median value (HR, 4.36; 95% CI 1.22–15.60). A positive association with CHD events was also observed when considering s-RNY1-5p as a continuous variable (p = 0.022). Based on our results, we conclude that serum s-RNY1-5p is an independent predictor of CHD events in a general male population and might be a relevant biomarker for early detection of cardiovascular diseases.

Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors

2005 ◽  
Vol 93 (05) ◽  
pp. 955-963 ◽  
Author(s):  
George Smith ◽  
Ann Rumley ◽  
Gordon Lowe ◽  
Shah Ebrahim ◽  
Debbie Lawlor
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Life Course ◽  
Socioeconomic Position ◽  
Cumulative Effect ◽  
Positive Association ◽  
Confounding Factors ◽  
Cross Sectional ◽  
Reactive Protein ◽  
The Life Course

SummaryA cross sectional and prospective analysis of 3,745 British women aged 60–79 years at baseline was undertaken. Among these women there were 570 prevalent cases of coronary heart disease (CHD) and 151 new cases among 12,641 person-years of follow up of women who were free of CHD at baseline. Both fibrinogen and CRP were associated with indicators of socioeconomic position in childhood and adulthood and there was a cumulative effect of socioeconomic position from across the life course. The age-adjusted odds ratio (95% confidence interval) of prevalent CHD for a 1 unit (1 g/L) increase in fibrinogen was 1.29 (1.12, 1.49); with full adjustment for all potential confounding factors this attenuated to 1.09 (0.93, 1.28). The hazards ratio for incident CHD among those free of disease at baseline was 1.28 (1.00, 1.64); with full adjustment for all potential confounding factors this attenuated to 1.09 (0.84, 1.44). Similar effects of adjustment for confounding factors were seen for the associations between CRP and both prevalent and incident CHD. By contrast, the strong positive association between smoking (an established causal risk factor for CHD) and CHD was not attenuated by adjustment for life course socioeconomic position or other risk factors. We conclude that fibrinogen and CRP predict CHD but may not be causally related to it.

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