scholarly journals Ocular manifestations in children with developmental delay in an eye hospital of northern Bangladesh

2021 ◽  
Vol 8 (12) ◽  
pp. 5682
Author(s):  
Rokhsana Afroze ◽  
Khairul Islam ◽  
Sajidul Huq
Keyword(s):  
Developmental Delay ◽  
Perinatal Asphyxia ◽  
Later Life ◽  
Poor Vision ◽  
Ophthalmic Examination ◽  
Ocular Manifestations ◽  
History Of ◽  
Systemic Problems ◽  
Medical Histories ◽  
Record Review

Background: The aim of this study was to identify common ocular manifestations in children with developmental delay in an eye hospital of northern part of Bangladesh.Methods: It was a retrospective medical record review of children with developmental delay who attended the pediatric ophthalmology department in an eye hospital from January 2019 to December 2019. Data were collected for their age, gender, past medical history, ophthalmic examination findings and systemic problems. Ophthalmic examination included examination of lid and adnexa, anterior and posterior segment examination and assessment of squint and refraction.Results: Medical records of 102 with developmental delay were identified and studied (59 boys and 43 girls, mean age 1.57 years, 53.9% aged <1 year). Of these children, 44 (43.1%) were referred by the pediatricians. The most common past medical histories were perinatal asphyxia (42.2%), history of convulsion (30.4%), neonatal seizures (9.8%) and history of speech delay (1%). On ophthalmic examination, 30 (29.5%) had poor vision, 20 (19.6%) had refractive error, 23 (22.5%) had Strabismus and 11 (10.8%) had nystagmus. Optic atrophy was also observed among 11 children (10.8%).Conclusions: Ocular manifestations are commonly seen in children with developmental delay which can be cause of severe visual impairment and overall disability in later life. Hence an early ophthalmologic screening and intervention in these children by developing good referral network between ophthalmologist and pediatricians can help to substantially improve the developmental and academic achievement. 

How Valid are Patient Reports of Family History of Illness?

1980 ◽  
Vol 19 (03) ◽  
pp. 162-164 ◽  
Author(s):  
Rachel Harris ◽  
W. Margaret ◽  
Kathleen Hunter
Keyword(s):  
Family History ◽  
Medical History ◽  
Cancer Patients ◽  
Cause Of Death ◽  
Death Certificate ◽  
Recall Rate ◽  
Patient Reports ◽  
Small Subgroup ◽  
History Of ◽  
Medical Histories

The recall rate of patients’ family medical histories was studied in 200 cancer and non-cancer patients. Data on age and cause of death for parents and grandparents were collected. Although most patients knew the age and cause of death of parents, less than half knew for grandparents. Cancer patients had significantly greater recall for maternally related relatives. A subsample of patients’ family medical histories was compared to death certificate data. Patients’ reports were found to be highly inaccurate. Since only a small subgroup could provide medical history data for grandparents, the generaliz-ability for history of family illness is questioned.

Knobloch Syndrome in Siblings with Posterior Fossa Malformations Along with Cerebellar Midline Cleft Abnormality Caused by Biallelic COL18A1 Mutation: Case-Based Review

2020 ◽  
Author(s):  
Siddaramappa J. Patil ◽  
Shruti Pande ◽  
Jyoti Matalia ◽  
Venkatraman Bhat ◽  
Minal Kekatpure ◽  
...  
Keyword(s):  
Posterior Fossa ◽  
Clinical Manifestations ◽  
Autosomal Recessive Disorder ◽  
Later Life ◽  
Facial Dysmorphism ◽  
Ocular Manifestations ◽  
Occipital Encephalocele ◽  
Knobloch Syndrome ◽  
Posterior Fossa Malformations ◽  
Midline Cleft

AbstractKnobloch syndrome (KS) is an autosomal recessive disorder caused by biallelic pathogenic variants in COL18A1. KS clinically manifests with the typical eye findings (high myopia, vitreoretinal degeneration, retinal detachment, and lens subluxation), variable neurological findings (occipital encephalocele, polymicrogyria, cerebellar malformations, epilepsy, and intellectual disability), and the other uncommon clinical manifestations. Literature review of all KS patients (source PubMed) was done with special reference to cerebellar abnormalities. Here, we report two siblings with typical KS with posterior fossa malformations and novel cerebellar midline cleft abnormality analyzed by whole exome sequencing. Known pathogenic homozygous variant c.2908C > T; (p.Arg970Ter) in exon 26 of COL18A1 was found as a cause for KS. These two siblings presented with early-onset severe ocular manifestations, facial dysmorphism, and variable central nervous system manifestations along with novel cerebellar midline cleft abnormality. The presence or absence of structural brain malformations and genotypes does not absolutely predict cognitive functions in KS patients. However, the presence of posterior fossa abnormality may be predictive for the development of ataxia in later life and needs further studies.

scholarly journals “Old wine in a new bottle” - post COVID-19 infection, central serous chorioretinopathy and the steroids

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Srinivasan Sanjay ◽  
Poornachandra B. Gowda ◽  
Bhimasena Rao ◽  
Deepashri Mutalik ◽  
Padmamalini Mahendradas ◽  
...  
Keyword(s):  
Virus Disease ◽  
Anterior Segment ◽  
Central Serous Retinopathy ◽  
Oral Antibiotics ◽  
Rt Pcr ◽  
Case Presentation ◽  
Ocular Manifestations ◽  
Corrected Distance Visual Acuity ◽  
History Of ◽  
The Right

Abstract Introduction Corona virus disease (COVID-19) pandemic can cause myriad of ocular manifestations. We report a case of unilateral multi focal central serous retinopathy, post COVID-19 infection in an Asian Indian female. Case presentation A 42-year-old female presented to us with unilateral blurring, in the right eye (OD), 12 days after COVID-19 infection. She had fever, chills, shortness of breath and cough with tiredness and was COVID- RT PCR positive. She was administered intravenous and oral antibiotics with injection heparin/remdesivir, during her 7 day stay at the hospital. She was also on steroid inhalers. She had no systemic history of note. On ocular evaluation, her corrected distance visual acuity was 20/40 in OD and 20/20 in left eye (OS). Anterior segment was normal. Anterior vitreous was clear. Fundus examination of the OD showed central serous retinopathy (CSCR) with OS being normal. Conclusion CSCR can occur post COVID-19 due to steroid administration and physicians administering it should be aware of this and refer the patients to an ophthalmologist earlier.

scholarly journals Stroke prediction in patients presenting with isolated dizziness in the emergency department

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
June-sung Kim ◽  
Hong Jun Bae ◽  
Muyeol Kim ◽  
Shin Ahn ◽  
Chang Hwan Sohn ◽  
...  
Keyword(s):  
Risk Factors ◽  
Emergency Department ◽  
Multivariate Analysis ◽  
Acute Stroke ◽  
Neurological Deficits ◽  
Cerebrovascular Injury ◽  
Risk Patients ◽  
History Of ◽  
Independent Risk Factors ◽  
Record Review

AbstractDiagnosing stroke in patients experiencing dizziness without neurological deficits is challenging for physicians. The aim of this study was to evaluate the prevalence of acute stroke in patients who presented with isolated dizziness without neurological deficits at the emergency department (ED), and determine the relevant stroke predictors in this population. This was an observational, retrospective record review of consecutive 2215 adult patients presenting with dizziness at the ED between August 2019 and February 2020. Multivariate analysis was performed to identify risk factors for acute stroke. 1239 patients were enrolled and analyzed. Acute stroke was identified in 55 of 1239 patients (4.5%); most cases (96.3%) presented as ischemic stroke with frequent involvement (29.1%) of the cerebellum. In the multivariate analysis, the history of cerebrovascular injury (odds ratio [OR] 3.08 [95% confidence interval {CI} 1.24 to 7.67]) and an age of > 65 years (OR 3.01 [95% CI 1.33 to 6.83]) were the independent risk factors for predicting acute stroke. The combination of these two risks showed a higher specificity (94.26%) than that of each factor alone. High-risk patients, such as those aged over 65 years or with a history of cerebrovascular injury, may require further neuroimaging workup in the ED to rule out stroke.

Malaria in Children in Chicago

PEDIATRICS ◽  
1993 ◽  
Vol 92 (1) ◽  
pp. 83-85
Author(s):  
Benjamin Emanuel ◽  
Neil Aronson ◽  
Stanford Shulman
Keyword(s):  
United States ◽  
Pediatric Population ◽  
The United States ◽  
Malaria Endemic Area ◽  
Overseas Travel ◽  
History Of ◽  
Record Review ◽  
Recent Immigration ◽  
Childhood Malaria ◽  
Retrospective Medical Record Review

Objective. To review the experience of a large children's hospital and two community hospitals in Chicago in which malaria was diagnosed in children during a recent 6-year period. Methods. Retrospective medical record review covering the years 1985 to 1990. Results. Twenty cases of childhood malaria were diagnosed, generally in patients hospitalized for fever unresponsive to oral antibiotics also associated with splenomegaly, with presumptive diagnoses of malignancy, typhoid fever, acute appendicitis, or urinary tract infection. History of recent immigration to the United States or travel to a malaria-endemic area was frequently not elicited until several days into hospitalization, thus delaying diagnosis and therapy. Conclusions. Because malaria in the United States pediatric population has increased as a result of foreign immigration and overseas travel, pediatricians must be alert to the possibility of malaria in febrile children, and the importance of antimalarial prophylaxis should be communicated to parents of children traveling to endemic areas.

scholarly journals Pharmaceuticals and modern statecraft in South Africa: the cases of opium, thalidomide and contraception.

2018 ◽  
Vol 44 (4) ◽  
pp. 253-262 ◽  
Author(s):  
Julie Parle ◽  
Rebecca Hodes ◽  
Thembisa Waetjen
Keyword(s):  
South Africa ◽  
Case Studies ◽  
20Th Century ◽  
Early 20Th Century ◽  
Pharmaceutical Regulation ◽  
Institutional Practices ◽  
Colonial Era ◽  
History Of ◽  
Medical Histories ◽  
Pharmaceutical Governance

This article provides a history of three pharmaceuticals in the making of modern South Africa. Borrowing and adapting Arthur Daemmrich’s term ‘pharmacopolitics’, we examine how forms of pharmaceutical governance became integral to the creation and institutional practices of this state. Through case studies of three medicaments: opium (late 19th to early 20th century), thalidomide (late 1950s to early 1960s) and contraception (1970s to 2010s), we explore the intertwining of pharmaceutical regulation, provision and consumption. Our focus is on the modernist imperative towards the rationalisation of pharmaceutical oversight, as an extension of the state’s bureaucratic and ideological objectives, and, importantly, as its obligation. We also explore adaptive and illicit uses of medicines, both by purveyors of pharmaceuticals, and among consumers. The historical sweep of our study allows for an analysis of continuities and changes in pharmaceutical governance. The focus on South Africa highlights how the concept of pharmacopolitics can usefully be extended to transnational—as well as local—medical histories. Through the diversity of our sources, and the breadth of their chronology, we aim to historicise modern pharmaceutical practices in South Africa, from the late colonial era to the Post-Apartheid present.

Ischaemic heart disease and pregnancy

Heart ◽  
2018 ◽  
Vol 105 (3) ◽  
pp. 189-195 ◽  
Author(s):  
Matthew Cauldwell ◽  
Lucia Baris ◽  
Jolien W Roos-Hesselink ◽  
Mark R Johnson
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Maternal Morbidity ◽  
Inflammatory Diseases ◽  
Later Life ◽  
Shock Delivery ◽  
Chronic Inflammatory Diseases ◽  
Prevalence Of Obesity ◽  
History Of ◽  
In Pregnancy

Although ischaemic heart disease is currently rarely encountered in pregnancy, occurring between 2.8 and 6.2 per 100 000 deliveries, it is becoming more common as women delay becoming pregnant until later life, when medical comorbidities are more common, and because of the higher prevalence of obesity in the pregnant population. In addition, chronic inflammatory diseases, which are more common in women, may contribute to greater rates of acute myocardial infarction (AMI). Pregnancy itself seems to be a risk factor for AMI, although the exact mechanisms are not clear. AMI in pregnancy should be investigated in the same manner as in the non-pregnant population, not allowing for delays, with investigations being conducted as they would outside of pregnancy. Maternal morbidity following AMI is high as a result of increased rates of heart failure, arrhythmia and cardiogenic shock. Delivery in women with history of AMI should be typically guided by obstetric indications not cardiac ones.

scholarly journals Health Monitor System

2021 ◽  
Vol 9 (VIII) ◽  
pp. 103-106
Author(s):  
M. Ujair Hoble
Keyword(s):  
Medical History ◽  
The People ◽  
Medical Sector ◽  
Medical Reports ◽  
History Of ◽  
Suitable Treatment ◽  
Medical Histories ◽  
Almost All ◽  
Health Monitor ◽  
Crucial Part

Health is a crucial part of human lives. Nowadays, healthcare is becoming vital each day, as there are lots of diseases that emerge around us. Technology is transforming the medical sector by massively impacting almost all practices and processes of medical professionals. Despite this, many of the people and medical staff still dealing with paper-based medical records and prescriptions while conducting treatment. When a patient wants to appoint any hospital or clinic, to carry previous medical reports or past prescriptions is becoming essential for them. It is necessary because the doctor gets an idea about the patient’s health status by referring to their previous medical histories, helping for better treatments and medications. However, patients cannot maintain every medical documentary for years. Conventionally, the doctor asks patients about their previous diseases, prescription, or medicine details orally, nevertheless it becomes difficult to get exact information from the patient. Sometimes, it becomes more important for the doctor to know about the medical history of a person so that they can provide suitable treatment with better clarity of that person’s health. Focussing on this, a smart medical assistant system is designed where doctors can record all prescriptions, treatment, or medical details of the patient on software instead of writing on a paper. All these records are stored in the central cloud and made visible to doctors as well as patients. Each patient has assigned a unique authentication card for maintaining the privacy of their medical history account. Doctors can access and update a patient’s medical history anytime and anywhere by logging into their account through a smartcard swipe. The system can avoid overdue to treatment decisions. Likewise, the system helps to keep transparency about medicines and treatment.

scholarly journals Tempering an Enlightened Educator: Frédéric-César de La Harpe at the Russian Imperial Court (1783–1795)

Slovene ◽  
2017 ◽  
Vol 6 (2) ◽  
pp. 365-384
Author(s):  
Andrei Yu. Andreev ◽  
Danièle Tosato-Rigo
Keyword(s):  
Early Childhood ◽  
Present Article ◽  
Later Life ◽  
Educational Process ◽  
French Language ◽  
Main Stage ◽  
Success Story ◽  
Imperial Court ◽  
The Everyday ◽  
History Of

Among all the educators who cared for him from his early childhood, Alexander I gave a particular honor to only one, the Swiss teacher Frédéric-César de La Harpe (1754–1838), who, invited to teach the French language, was further his instructor in geography, history, arithmetic, and geometry, as well as the foundations of philosophy. This Swiss teacher has been regarded in historical studies as the fortunate “chosen one” by Catherine II, who summoned him to direct Alexander’s education and who rewarded him accordingly afterwards. The present article peers into the backstage of the long educational process (1783–1795) in which he was engaged, revealing the less idyllic facts. Based on unpublished documents in Russian and Swiss archives, this study presents a picture of the place of an educator on the main stage of his activity, the Russian Imperial court, and thus the interplay of the history of practice and of ideas and their representations. Did La Harpe himself choose to work as an educator? Did Catherine II really search and find the Swiss teacher for his abilities? Did his teaching indeed represent a concretization of Catherine’s thoughts on this matter? And finally, how did La Harpe himself estimate his situation at the court, which was transformed into a “success story” only after 1814? This article, offering some answers to these questions, adds to the analysis the different circumstances of La Harpe’s appearance and later life at the court; the difficulties he faced in spite of the support of Catherine II, which was, regrettably, withdrawn unexpectedly; and, finally, the permanent discrepancies between his pedagogical ideals and the everyday studies in which he engaged.

scholarly journals Analysis of Clinical Characteristics of 19 Patients with Endophthalmitis Caused by Liver Abscess

2021 ◽  
Author(s):  
guangsen liu ◽  
Yue Li ◽  
Wei Wang ◽  
Lei Gao
Keyword(s):  
Visual Acuity ◽  
Liver Abscess ◽  
Diagnosis And Treatment ◽  
Endogenous Endophthalmitis ◽  
Klebsiella Pneumonia ◽  
Microbial Culture ◽  
Poor Vision ◽  
Ocular Symptoms ◽  
History Of ◽  
First Time

Abstract Objective: To analyze the clinical features, treatment, and prognosis of endophthalmitis caused by a liver abscess.Methods: All cases of endogenous endophthalmitis caused by a liver abscess in our hospital in the past 7 years were analyzed retrospectively. The data collected included age, sex, history of diabetes, initial and final vision, pathogen, course of the disease, treatment, and prognosis.Results: 21 eyes of 19 patients were complicated with liver abscess. The average age was 55.9 ±9.8 years old, including 10 males (52.6%) and 9 females (44.4%), 13 patients complicated with diabetes (71.4%), 14 patients (66.7%) first went to the ophthalmology department for diagnosis and treatment and 5 with hepatobiliary surgery (33.3%). 14 patients had a fever before onset, with an average fever time of 5.8 days. Before treatment, the duration of ocular symptoms was 7.71 ±6.68 days, 5.71 ±1.25 days for patients who go to ophthalmology for diagnosis and treatment for the first time, and 12.2 ±3.58 days for patients who go to other departments. After treatment, the average visual acuity of 21 eyes was 0.013, and the average best-corrected visual acuity was 0.79. In the 21 eyes, vitreous fluid culture was positive in 7 eyes (33.3%), all of which were Klebsiella pneumonia. Among the 14 patients with fever during hospitalization, 5 cases were positive for blood microbial culture, all of which were Klebsiella pneumonia. After vitrectomy, the average visual acuity was improved by 4.90 ±2.47 letters and that of patients without vitrectomy was-0.25±0.16letters. The visual acuity of patients who underwent postoperative visual was significantly better than that of patients without postoperative visual (P＜0.096). The visual acuity of patients without vitrectomy was significantly higher than that of patients without vitrectomy (P ＜0.01). 3 eyes (33.3%) of 9 eyes in the IVI group were removed because of uncontrolled inflammation, and 1 eye of 12 eyes in the PPV group was removed because of inflammation recurrence.Conclusion: The prognosis of endogenous endophthalmitis caused by liver abscess is generally poor, but early treatment can save part of the vision. The first visit non-ophthalmology department will delay the early diagnosis of the disease. Diabetes is an important risk factor for endogenous endophthalmitis and poor vision in patients with liver abscess. Klebsiella pneumonia is the main pathogen of intraocular infection. Vitrectomy combined with vitreous injection of antibiotics can improve the prognosis. A systematic and thorough treatment of a liver abscess is of great significance to prevent the recurrence of endophthalmitis in a liver abscess.

Sign in / Sign up

Export Citation Format

Share Document