scholarly journals Metagenomic approach in the investigation of new bioactive compounds in the marine environment.

2012 ◽  
Vol 59 (4) ◽  
Author(s):  
Agnieszka Felczykowska ◽  
Sylwia Kamila Bloch ◽  
Bożena Nejman-Faleńczyk ◽  
Sylwia Barańska
Keyword(s):  
Biological Activity ◽  
Natural Resources ◽  
Bioactive Compounds ◽  
Marine Environment ◽  
Marine Microorganisms ◽  
Microbial Biodiversity ◽  
The World ◽  
Research Intensity ◽  
Efficient Screening ◽  
Metagenomic Approach

The marine environment is estimated to be one of the most significant sources of biological activity in the world. In the last few decades an increase in the research intensity conducted on marine microorganisms has been observed, which confirms the great potential of these organisms in the field of bioactive compounds' production. In order to efficiently use the natural resources of the marine environment, metagenomics can be applied. This powerful technique allows for efficient screening of microbial biodiversity for bioactive compounds. The primary aim of this review is to present some aspects of the construction of metagenomic libraries, and strategies of screening for novel bioactives in the marine surrounding. This paper also illustrates several examples of the application of metagenomic methods in the discovery of novel enzymes and drugs in various marine environments.

scholarly journals Marine Bacteria versus Microalgae: Who Is the Best for Biotechnological Production of Bioactive Compounds with Antioxidant Properties and Other Biological Applications?

Marine Drugs ◽  
2019 ◽  
Vol 18 (1) ◽  
pp. 28 ◽  
Author(s):  
Masoud Hamidi ◽  
Pouya Safarzadeh Kozani ◽  
Pooria Safarzadeh Kozani ◽  
Guillaume Pierre ◽  
Philippe Michaud ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Marine Environment ◽  
Biological Diversity ◽  
Current Knowledge ◽  
Antioxidant Properties ◽  
Biological Properties ◽  
Marine Microorganisms ◽  
Biotechnological Production ◽  
Potential Applications ◽  
Chemical Conditions

Natural bioactive compounds with antioxidant activity play remarkable roles in the prevention of reactive oxygen species (ROS) formation. ROS, which are formed by different pathways, have various pathological influences such as DNA damage, carcinogenesis, and cellular degeneration. Incremental demands have prompted the search for newer and alternative resources of natural bioactive compounds with antioxidant properties. The marine environment encompasses almost three-quarters of our planet and is home to many eukaryotic and prokaryotic microorganisms. Because of extreme physical and chemical conditions, the marine environment is a rich source of chemical and biological diversity, and marine microorganisms have high potential as a source of commercially interesting compounds with various pharmaceutical, nutraceutical, and cosmeceutical applications. Bacteria and microalgae are the most important producers of valuable molecules including antioxidant enzymes (such as superoxide dismutase and catalase) and antioxidant substances (such as carotenoids, exopolysaccharides, and bioactive peptides) with various valuable biological properties and applications. Here, we review the current knowledge of these bioactive compounds while highlighting their antioxidant properties, production yield, health-related benefits, and potential applications in various biological and industrial fields.

scholarly journals Australia’s Endeavours in Maritime Enforcement

2018 ◽  
Vol 6 (2) ◽  
pp. 219-244
Author(s):  
James Wraith ◽  
Clive Schofield
Keyword(s):  
Natural Resources ◽  
Marine Environment ◽  
International Partnerships ◽  
The Third ◽  
Extreme Dependence ◽  
Large Island ◽  
The World ◽  
Innovative Approaches

Abstract Australia is deeply connected to the ocean. A uniquely large island nation with a long coastline and few close neighbours, Australia benefits from an immense maritime domain, the third largest in the world. However, with relatively few maritime enforcement resources and an extreme dependence on sea bourne trade, maritime enforcement Australia faces an extremely difficult task in monitoring and ensuring compliance with national laws throughout its maritime jurisdiction. We highlight current threats to Australia’s marine environment including protection of natural resources, piracy, terrorism and illegal arrivals, and examine Australia’s capabilities, legislation and approach to combating these risks. Essential to Australia’s strategy is collaboration across domestic civil and defence agencies, use of innovative approaches and technologies, and regional and international partnerships through creative agreements and treaties.

The Tourism Industry and the Marine Environment

2020 ◽  
Author(s):  
Professor John Swarbrooke
Keyword(s):  
Natural Resources ◽  
Marine Environment ◽  
Government Regulation ◽  
Good Practice ◽  
Tourism Industry ◽  
The Other ◽  
Tourist Destinations ◽  
The World ◽  
Negative Impacts ◽  
Responsible Tourism

Throughout this book we have been looking, primarily, at the negative impacts of tourism on the marine environment. It would appear reasonable to lay the blame for this at the door of the tourism industry, which facilitates the vacations that cause this harm and makes money from exploiting the marine environment and the other natural resources of tourist destinations around the world. However, things are not always that simple, as we will see in this chapter. For in tourism, and certainly land-based tourism, it has often been the tourism industry itself, and particularly the tour operation sector, which has often been leading the way on responsible tourism, often with little encouragement from the tourists themselves and usually no government regulation forcing them to act. Their motives may not have been altruistic but, nevertheless, they have taken action on a number of fronts, while events like the Responsible Tourism Days at World Travel Market in London have sought to share good practice around the tourism industry.

Peran Pengawasan Internal Dalam Menghindari Kutukan Sumber Daya Alam

Liquidity ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 1-9
Author(s):  
Andilo Tohom
Keyword(s):  
Natural Resources ◽  
Internal Audit ◽  
Rent Seeking ◽  
Rich Country ◽  
Literature Study ◽  
Indonesian Government ◽  
The World ◽  
Policies And Programs ◽  
The Right

Indonesia is one of many countries in the world so called resource-rich country. Natural resources abundance needs to be managed in the right way in order to avoid dutch diseases and resources curses. These two phenomena generally happened in the country, which has abundant natural resources. Learned from Norwegian experiences, Indonesian Government need to focus its policy to prevent rent seeking activities. The literature study presented in this paper is aimed to provide important insight for government entities in focusing their policies and programs to avoid resources curse. From the internal audit perspective, this study is expected to improve internal audit’s role in assurance and consulting.

نُدرة الموارد وعلاقتها بالبيئة من وجهة نظر إسلاميّة The Issue of Scarcity of Resources and Its Relationship to the Environment

2014 ◽  
Vol 11 (1) ◽  
pp. 01
Author(s):  
حسن بن إبراهيم الهنداوي (Hassan Hendawi)
Keyword(s):  
Natural Resources ◽  
Human Existence ◽  
Economic Resources ◽  
Human Beings ◽  
Human Needs ◽  
Modern Economy ◽  
The People ◽  
The World ◽  
Scarcity Of Resources ◽  
Economic Dilemma

الملخّصإنّ الفقر والإملاق من المشكلات الرئيسة التي يواجهها العالم اليوم، ومن أسبابها ندرة الموارد الاقتصادية الشديدة وندرة الغذاء والماء. فندرة الموارد وقلتها كانت ذات أثر مباشر في قتل الملايين من الأنفس البشريّة. وتعدّ ندرة الموارد عند الاقتصاديين الخطر الأساس الذي يهدد الوجود البشري في هذا العصر. ويعتبرها الاقتصاديّون كذلك معضلة اقتصادية ناتجة عن رغبات الإنسان غير المتناهية مقابل موارد محدودة ومتناهية. ومن الأمور التي يقترحها الاقتصاديون من اجل التغلب على هذه المشكلة أن النّاسن ينبغي عليهم أن يختاروا الموارد الضرورية والحاجية لتلبية رغباتهم. فمفهوم الندرة من منظور الاقتصاد التقليدي يعني موارد محدودة في العالم مقابل حاجات ورغبات غير محدودة. وسبب ذلك عند الاقتصاديين أن الطبيعة لا توفر موارد كافية لتلبية حاجات الناس ورغباتهم غير المتناهية. ونظرة الإسلام التي يمثلها القرآن الكريم والسنة النبوية الشريفة لمسألة الندرة نظرة مختلفة تماما عن نظرة الاقتصاد التقليدي. ويعنى هذا البحث ببيان أن الندرة ليست مشكلة الطبيعة التس سخّرها الله تعالى للإنسان،  ولكن المشكلة في أخلاقيات الناس وتصرفاتهم في الموارد الطبيعية وطريقتهم في الانتفاع بها التي أدت إلى إدخال الضرر والفساد على الموارد الموجودة.الكلمات المفتاحية: الإسلام، ندرة الموارد، الاقتصاد المعاصر، الموارد الطبيعية، الطبيعة. **************************************               AbstractAmong the main problems that the world is facing today are poverty and destitution caused by severe scarcity of economic resources and the scarcity of food and water. The lack of resources has already caused the death of millions of human beings. The scarcity of resources is counted by economists as the primary danger that threatens the human existence. Economists also consider it an economic dilemma caused by infinite human desires against limited and finite resources. In order to overcome this problem among the suggestions made by economists is that human beings should choose only necessary resources to satisfy their desires. The conventional concept of scarcity is that the resources in the world are limited vis-à-vis the unlimited human needs and desires. The reason for that according to economists is that the nature does not provide sufficient resources to meet people’s endless needs and desires. Islamic approach as represented by the Holy Qur’an and the Sunnah to the issue of scarcity is essentially different from the conventional viewpoint of economists. This paper proposes and explains that the problem is not in the nature which Allah has made subservient to man, but it is in the ethics of the people and their behaviour and way of utilization of natural resources, which ultimately damage and corrupt the available resources.Keywords: Islam, Scarcity of Resources, Modern Economy, Environmental Resources, Nature.

Beritakan Injil Kepada Segala Makhluk

2018 ◽  
Vol 1 (1) ◽  
pp. 56-69
Author(s):  
Ibelala Gea
Keyword(s):  
Natural Resources ◽  
Human Behavior ◽  
Great Commission ◽  
The World ◽  
The Dead

This article aims to describe the results of research on how to preach the gospel to all beings, based on Mark 16:15-16. Preaching the gospel is a great commission from the Lord Jesus to His followers after His resurrection from the dead. The world is the address of the gospel preaching, not only to man but to all beings.The Gospel writer of  Mark wants to explain that the world is synonymous with evil, therefore the gospel serves to salt the evil world, so when Iniil is preached to the wicked, it is expected to change the mindset and human behavior.Greedy and greedy human behavior that only views nature as a commodity. Human evil is seen when only the task of exploiting natural resources and forget the responsibility of caring for, nurturing nature and the environment. Gospel preaching aims to awaken peoples not only to view nature as power (dominio) but as a fellow of creatures, and friends (communio). Preach the gospel to all beings and receiving each other with referring to reduce, reuse, recycle and replace as a responsibility to God who has given the mandate for us. AbstrakArtikel ini bertujuan untuk mendeskripsikan hasil penelitian tentang bagaimana memberitakan Injil kepada  seluruh makhluk, bertolak dari Markus 16:15-16. Memberitakan Injil adalah amanat agung dari Tuhan Yesus kepada para pengikut-Nya setelah kebangkitan-Nya dari antara orang mati.Dunia adalah sebagai alamat pemberitaan Injil, bukan hanya kepada manusia melainkan kepada segala makhluk. Penulis Injil Markus hendak menjelaskan bahwa dunia identik dengan kejahatan, sebab itu Injil berfungsi menggarami dunia yang penuh kejahatan itu, karena itu ketika Iniil diberitakan kepada orang-orang jahat, diharapkan akan mengubah mindset dan perilaku manusia. Perilaku manusia yang serakah dan tamak yang hanya memandang alam sebagai komoditi. Kejahatan manusia terlihat ketika hanya bertugas mengeksploitasi sumber-sumber daya alam dan lupa pada tanggung jawab merawat, memelihara alam dan lingkungan hidupnya.  Pemberitaan Injil menyadarkan manusia agar tidak hanya memandang alam sebagai kekuasaan (dominio) tetapi sebagai sesama ciptaan, sahabat yang bersifat communio. Memberitakan Injil kepada seluruh makhluk dan menghargai segala makhluk dengan saling memberi dan menerima dengan mengacu pada pola-pola reduce, reuse, recycle dan replace sebagai tanggung jawab kepada Tuhan yang telah memberi amanat.

Synthesis and Biological Activity Study of Tanshinone Derivatives: A Literature and Patent Review

2020 ◽  
Vol 20 (28) ◽  
pp. 2520-2534
Author(s):  
He Huang ◽  
Chuanjun Song ◽  
Junbiao Chang
Keyword(s):  
Biological Activity ◽  
Herbal Medicine ◽  
Chemical Synthesis ◽  
Bioactive Compounds ◽  
Chinese Herbal Medicine ◽  
Salvia Miltiorrhiza ◽  
Salvia Miltiorrhiza Bunge ◽  
Chinese Herbal ◽  
Patent Review

: Tanshinones are a class of bioactive compounds present in the Chinese herbal medicine Danshen (Salvia miltiorrhiza Bunge), containing among others, abietane diterpene quinone scaffolds. Chemical synthesis and biological activity studies of natural and unnatural tanshinone derivatives have been reviewed in this article.

Exploring Antimicrobials from the Flora and Fauna of Marine: Opportunities and Limitations

2020 ◽  
Vol 17 (4) ◽  
pp. 507-514 ◽  
Author(s):  
Krishnamoorthy Venkateskumar ◽  
Subramani Parasuraman ◽  
Leow Y. Chuen ◽  
Veerasamy Ravichandran ◽  
Subramani Balamurgan
Keyword(s):  
Antimicrobial Resistance ◽  
Bioactive Compounds ◽  
Marine Environment ◽  
World Health ◽  
Future Research ◽  
Marine Biodiversity ◽  
Marine Resources ◽  
Living Space ◽  
Alternative Sources ◽  
Health Organization

About 95% of earth living space lies deep below the ocean’s surface and it harbors extraordinary diversity of marine organisms. Marine biodiversity is an exceptional reservoir of natural products, bioactive compounds, nutraceuticals and other potential compounds of commercial value. Timeline for the development of the drug from a plant, synthetic and other alternative sources is too lengthy. Exploration of the marine environment for potential bioactive compounds has gained focus and huge opportunity lies ahead for the exploration of such vast resources in the ocean. Further, the evolution of superbugs with increasing resistance to the currently available drugs is alarming and it needs coordinated efforts to resolve them. World Health Organization recommends the need and necessity to develop effective bioactive compounds to combat problems associated with antimicrobial resistance. Based on these factors, it is imperative to shift the focus towards the marine environment for potential bioactive compounds that could be utilized to tackle antimicrobial resistance. Current research trends also indicate the huge strides in research involving marine environment for drug discovery. The objective of this review article is to provide an overview of marine resources, recently reported research from marine resources, challenges, future research prospects in the marine environment.

Flavones and Their Analogues as Bioactive Compounds – An Overview

2019 ◽  
Vol 16 (4) ◽  
pp. 377-391 ◽  
Author(s):  
B.S. Jayashree ◽  
H. Venkatachalam ◽  
Sanchari Basu Mallik
Keyword(s):  
Biological Activity ◽  
Free Radical ◽  
Bioactive Compounds ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Cost Effective ◽  
Free Radical Scavenging ◽  
Polyphenolic Compounds ◽  
Pharmacological Activities ◽  
Poor Solubility

Flavonoids constitute a large group of polyphenolic compounds that are known to have antioxidant properties, through their free radical scavenging abilities. They possess a chromone (γ- benzopyrone) moiety, responsible for eliciting many pharmacological activities. Even though, natural flavonoids are highly potent, owing to their poor solubility, they are less used. Therefore, attempts have been made to improve their stability, solubility, efficacy and kinetics by introducing various substituents on the flavone ring. For nearly the last two decades, flavones were synthesized in our laboratory by simple, convenient and cost-effective methods, with the knowledge of both synthetic and semi-synthetic chemistry. In this direction, it was considered worthwhile to present an overview on the synthesized flavonoids. This review creates a platform for highlighting various modifications done on the flavone system along with their biological activity.

The Challenges of Implementing E-Commerce in Kurdistan of Iraq

2016 ◽  
Vol 2 (3) ◽  
pp. 528
Author(s):  
Ako Abubakr Jaffar ◽  
Mazen Ismaeel Ghareb ◽  
Karzan Hussein Sharif
Keyword(s):  
Middle East ◽  
Natural Resources ◽  
Online Shopping ◽  
Deep Understanding ◽  
The Other ◽  
Regional Government ◽  
Security Measures ◽  
Unique Region ◽  
Government Organizations ◽  
The World

The Retailers all over the world are prospering from the burgeoning trend of online shopping. Kurdistan Regional Government is still struggling to grow its e-commerce markets. On the other hands e-commerce in Various countries in the Middle East have some of the world’s highest internet and mobile penetration rates. Alternative payments methods are quickly expanding, and having access to some of the world’s most coveted natural resources that allows countries in their region to have some of the highest GDP in the world. There are several challenges prevalent in the KRG Region market that will require international merchants to develop strategies based on innovation and vigilance. This unique region is plagued with complications many other countries have little to no experience with e-commerce, which highlights the need for retailers to have a deep understanding as to how this region operates before they can begin finding solutions. One of the biggest concerns today's consumers have is the risk of fraud when they are shopping online. With highly sophisticated malware and perceptive cybercriminals, customers' card and bank information can easily be stolen if a merchant does not take the proper security measures. In this paper we summarize all challenges need to be addressed in KRG in order to make correct steps to apply e-commerce in KRG. Finally, the recommendations and framework are proposed for e-commerce to encourage government, organizations, and people to take advantages from e-commerce.

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