scholarly journals Use of “Kayod” Preparation in Cows

2021 ◽  
Author(s):  
Yulia Luschai ◽  
Olga Dutova ◽  
Elena Shaganova ◽  
Irina Pleshakova ◽  
Elena Mashkina
Keyword(s):  
Metabolic Disorders ◽  
White Blood Cells ◽  
Clinical Signs ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Total Calcium ◽  
Single Use ◽  
Biogeochemical Provinces ◽  
Experimental Group ◽  
Subcutaneous Implant

The Altai territory is an agricultural region; it is a biogeochemical province deficient in iodine. We conducted a study of metabolic disorders in cows that had hypofunction of the thyroid gland. Our research is devoted to the expediency of a single use of the drug “Kayod” administered in the form of a subcutaneous implant in order to normalize the therapeutic status of animals suffering from a chronic lack of iodine in their diet. The purpose of this work is to justify not only the use of the preparation “Kayod” in animals kept in the biogeochemical provinces deficient in iodine, but also the use of tablets administered through a subcutaneous implant. We found a significant increase in the amount of hemoglobin and a decrease in the number of white blood cells in the blood of animals after the use of “Kayod”, and in the second experimental group, these indicators were slightly higher than in the first one. Indicators of the level of total protein and reserve alkalinity of blood were within the limits of physiological norms, but in the experimental groups they were slightly higher than in the control group. The level of total calcium and carotene in the blood of animals in the experimental groups, especially the second, significantly exceeded the level of the same substances in the blood of the animals in the control group. However, the level of inorganic phosphorus tended to decrease. The level of glucose in the blood of cows in the experimental group increased significantly more than in the blood of cows in the control group. This increase was particularly significant in the blood of animals in the second experimental group. When the preparation “Kayod” was used in the form of a subcutaneous implant, there were no clinical signs of hypothyroidism in the cows of the first experimental group after nine weeks. In the cows of the second experimental group, the condition of the cows returned to normal after six weeks. Keywords: Cows, iodine, hypothyroidism, implant, “Kayod

scholarly journals State of protein and mineral exchange in broiler-chickens for the use of Zinc and Mangane chelates

2019 ◽  
pp. 85-94
Author(s):  
V. Sakara ◽  
A. Melnyk ◽  
F. Markhenkov
Keyword(s):  
Total Protein ◽  
Broiler Chickens ◽  
Zinc Content ◽  
Calcium Content ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Control Group ◽  
Total Protein Content ◽  
Total Calcium ◽  
Experimental Group

The results of the application of a complex of Zinc and Manganese chelates to protein, macro- and micro-mineral exchanges in the body of broiler chickens of the Cobb 500 cross-breed are presented. The administration of Zn and Mn chelates in a dose of 0,2 ml/l for chicken broilers of 23 days of age (1st experimental group) during 14 days influenced the increase in the total protein content to 35,3±0,8 g/l, which is 8 % higher compared with the control – 32,5±0,7 g/l (p<0,01 ) The concentration of total Calcium in serum of broiler chickens 37-day-old (end of trial) was higher in the first experimental group by 7,3 % (2,05±0,06 mmol/l) compared to control – 1,9±0,03 mmol/l. In the second group, where chelates were administered in a dose of 0,4 ml/l of water, the Calcium content was 2,0±0,02 mmol/l, which is 5 % more than the control group. The two-week application of Zn and Mn chelates also led to an increase in the level of inorganic Phosphorus in the serum of the first group to 2,6±0,12 mmol/l (+ 11,5 %) compared with the control group. After administration of chelates Zn and Mn at doses of 0,2 ml/l water, the Zinc content was higher by 4,3% (23,5±0,2 μmol/l) compared to control – 22,5±0,34 μmol/l (p<0,01). In the second group, where the dose of chelates was 0,4 ml/l, the concentration of Zinc was 23,6±0,16 μmol/l, which is more than 4,6 % for control (p<0,01). At the end of the study, the content of Manganese in serum of broiler chickens in the first group was 1,9±0,07 μmol/l (p<0,05), which is 10,4% higher compared with the control – 1,7±0,06 μmol/l (3rd sampling). The level of this element in the second group was 2,0±0,08 μmol/l (p<0,01), which is higher by 16,7 % relative to the control. At the end of the experiment, the coupon concentration in the first and second experimental groups was 12,6 and 9,3 % higher, compared with control, 7,0±0,37 μmol/l. In turn, the serum Ferrum content of the first group was greater by 9,3 % (19,3±0,69 μmol/l), and the second by 6,7 % (18,8±0,47 μmol/l) compared to the bird of the control group. Key words: chicken broilers, chelates, Zinc, Manganese, Cuprom, Ferrum, metabolism.

scholarly journals THE CHANGES OF SOME INDICES OF BIOCHEMICAL STATUS IN COWS WITH METABOLIC DISORDERS

2019 ◽  
pp. 62-66
Author(s):  
A. V. Trebukhov ◽  
A. A. Elenshleger
Keyword(s):  
Metabolic Disorders ◽  
Ketone Bodies ◽  
Mineral Metabolism ◽  
Biochemical Study ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Phosphorus Concentration ◽  
Total Calcium ◽  
Before And After ◽  
Apparently Healthy

Under present-day conditions of market economy, the requirements to the quality and quantity of livestock products increase significantly, and this leads to significant intensification of production and, as a consequence, to the development of metabolic disorders including ketosis in highly productive cows. The research goal was to study protein and mineral metabolism in ketotic cows before and after calving. The studies were conducted on the Training Farm «Prigorodnoye» in the City of Barnaul in autumn and winter in comparable Black-Pied cows. Two groups of cows were formed: the trial group consisted of ketotic cows; the control group consisted of apparently healthy cows. These cows underwent clinical and biochemical examination. The biochemical study of blood determined the following: total protein, albumins, alpha-globulins, beta-globulins, gamma-globulins, total calcium, inorganic phosphorus and ketone bodies. The biochemical blood tests were run 4 times: 2 months and 1 month before calving, and in 10 days and in 1 month after calving. It was found that the change of protein metabolism indices in ketotic cows showed a profound disorder of the protein synthesis function of liver both before and after calving. The level of total calcium in the blood of ketotic cows was characterized by lower values as compared to that in healthy comparable cows. At the same time, the dynamics of inorganic phosphorus concentration change did not have significant differences between ketotic and healthy cows. Total calcium content in ketotic cows increased one month before calving while in apparently healthy cows this index increased after calving only. The concentration of ketone bodies in the blood of ketotic cows was significantly higher than that of apparently healthy cows throughout the study.

Influence of DAFS-25+polizon composition on blood and functional state of liver of steers at fattening

2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  
Keyword(s):  
Functional State ◽  
White Blood Cells ◽  
Live Weight ◽  
The Body ◽  
Farm Animals ◽  
Control Group ◽  
Standard Diet ◽  
The Impact ◽  
Experimental Group ◽  
Stimulation Of

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.

INFLUENCE OF STOCK HOUSE LIGHT ON DAIRY PRODUCTIVITY OF COWS

2020 ◽  
Keyword(s):  
Blood Serum ◽  
Physiological State ◽  
Light Level ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Hemoglobin Content ◽  
Milk Productivity ◽  
Reproductive Ability ◽  
The Cost ◽  
Experimental Group

The article is devoted to the solution of an urgent problem- influence of different lighting modes on the dairy productivity of cows. 2 groups of cows with 20 heads each were formed. In control group, light in the cowshed was 50-75 Lux for a light period of 7.5 h in January to 16.5 h in June, and in experimental group - 150-200 Lux and 16 h, respectively. It was found that the intensity and duration of illumination affects physiological state, reproductive ability and milk productivity of cows. In the experimental group of cows, compared with the control group, hemoglobin content in blood increased by 4.6% (P < 0.01), red blood cells - by 20.6% (P < 0.05), total protein - by 11.2% (P < 0.001), glucose - by 39.1% (P < 0.05). There was a tendency to increase the total calcium and inorganic phosphorus in blood serum of cows of the experimental group. The level of alkaline phosphatase in blood serum of cows in the control group was 71.5% (P < 0.01) higher than that of cows in the experimental group. Milk yield per 1 cow in the experimental cowshed was 433 kg more than in the control. The cost of 1 kg of milk in the experimental group was 0.94 rubles lower, and the profitability of milk production and sales is 9.42% higher than in the control group. To increase the milk productivity of cows, it is recommended to increase light level in barns for tethered keeping to 150-200 Lux, with the duration of lighting in the winter and transition periods of year up to 16 hours per day.

scholarly journals Метаболічний профіль крові корів, хворих на післяродову гіпокальціємію

2013 ◽  
pp. 76-80
Author(s):  
Л. Л. Юськів ◽  
В. В. Влізло
Keyword(s):  
Fatty Acids ◽  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Total Protein ◽  
Clinical Signs ◽  
Inorganic Phosphorus ◽  
Total Calcium ◽  
25 Hydroxycholecalciferol

Проведено дослідження вмісту 25-гідроксихолекальциферолу (25-ОНD3), паратиреоїдного гормону (ПТГ) та кальцитоніну (КТ), а також кальцію загального, зв'язаного з білком та ультрафільтрувального, неорганічного фосфору, маґнію, активності лужної фосфатази, неетерифікованих жирних кислот (НЕЖК), глюкози і білка у крові корів, хворих на післяродову гіпокальціємію. Встановлено, що у крові корів із клінічними ознаками післяродової гіпокальціємії вміст 25-ОНD3 був вищим, а вміст ПТГ і КТ – нижчим, порівняно зі здоровими коровами в 1–2-й день після отелення. Водночас у крові корів, хворих на післяродову гіпо-кальціємію, знижується вміст загального, білокзв’язаного та ультрафільтрувального кальцію, неорганічного фосфору, глюкози, загального білка й підвищується кількість НЕЖК, маґнію, а також активність лужної фосфатази. It was researched the content of 25-hydroxycholecalciferol (25-OND3), parathyroid hormone (PTH) and calcitonin (CT) and total calcium bounded with the protein and ultrafiltered inorganic phosphorus, magnesium, alkaline phosphatase, nonetherified fatty acids (NEFA), glucose and protein in the blood of cows suffering from postpartum hypocalcemia. It was found that in the blood of cows with clinical signs of postpartum hypocalcemia ,25- OHD3 content was higher, but the content of PTH and CT - lower in coparisant with healthy cows within 1-2 days after calving. However, in the blood of cows suffering from postpartum hypocalcemia was decreasing concentration of total, protein-linked and ultrafiltrates calcium, inorganic phosphorus, glucose, total protein and was increasing concentration of NEFA, magnesium and activity of alkaline phosphatase.

MONIZEN FORTE FOR LAMBS PARASIT-IC DISEASES

2020 ◽  
Vol 2 ◽  
pp. 84-87
Author(s):  
E. S. Engasheva ◽  
◽  
V. I. Kolesnikov ◽  
Keyword(s):  
Clinical Signs ◽  
Live Weight ◽  
Control Group ◽  
Not Given ◽  
The North ◽  
Condi Tions ◽  
High Infection ◽  
Mucous Discharge ◽  
And Control ◽  
Experimental Group

The Monizen Forte test for parasitic sheep diseases was tested under production condi-tions on 460 lambs of the North Caucasian breed, with a live weight of 25-30 kg, with high infection with nematodes, cestodes and larvae of the nasopharyngeal gadfly (Oestrus ovis), which were given orally in a mixture with half the normal rate of concentrated feed, the test drug in a dose of 1 ml per 20 kg of the animal weight. Experienced (20 ani-mals) and control (10 animals) groups of lambs with an average live weight of 28 kg were selected from these lambs according to the principle of analogues. To the lambs of the control group, the drug was not given. 10 days after administration of the drug by clini-cal and coprological studies, it was found that the lambs of the experimental group, the intensity of nematode invasion decreased and the drug’s intensity (IE) was 96.7%, and the extensivity (EE) was 95%. The lambs of the experimental group before the introduction of the drug were 40% invaded with moniesia and 50% dictiocauli, and after using Monizen Forte they were released - the ex-tensibility (EE) was 100%. Lambs of the control (untreated) group, the intensity and extent of infection with nematodes and ces-todes remained at the same level as at the beginning of the experiment. All 10 lambs (50%) of the experimental group, the clinical signs of estrosis (sneezing, snorting, serous-mucous discharge from the nose) disap- peared, and the lambs of the control group have these clinical signs persisted.

scholarly journals State of metabolism of cows at dry period as the basis for reasoning of preven-tion and treatment of calves with gastrointestinal diseases

2019 ◽  
Vol 21 (93) ◽  
pp. 53-59
Author(s):  
V. Honcharenko ◽  
G. Gryshchuk ◽  
S. Sheremet
Keyword(s):  
Group Treatment ◽  
Biochemical Parameters ◽  
Metabolic Disorders ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Second Phase ◽  
Dry Period ◽  
Mineral Supplement ◽  
Treatment Regimens ◽  
Experimental Group

One of the real ways of increasing the production of livestock products is to increase the conservation of young animals, the mortality rate of which remains at this time still very high. Many calf treatment regimens have been developed, but they are not always effective, which prompts scientists and practitioners to improve already known methods of treatment, to find and justify new medical preparation. Material for research were dry-cows, healthy and sick calves. After the clinical examination of cows, the experiment was conducted in two phases: the first phase – in 3 groups of cows, the second – in clinical healthy and sick calves. Mineral supplement of Sapocorm were added to the first experimental group of cows; cows of the second experimental group – the preparation Betamint; animals of control group get basic diet. At the second phase, a group of healthy calves, as well as control and two experimental groups of patients were formed. The first group was treated with Intecol in combination with the probiotic Vetom. Calves of the second group – the preparation Intecoll, but in a complex with electrolyte solution Electrosol oral. The calves of the control group were treated with 4% solution of gentamicin sulfate and 30% solution of natrium thiosulfate. It was found out that during the dry period, cows were often subjected to metabolic disorders, and the causes of digestive disorders in calves were associated with a metabolic disorders in cows as a result of malnutrition. In the first stage of the research, the data obtained show the stimulatory effect of Betamint on the processes of hemopoiesis of the cows. In other side,  the probable magnification increase hemoglobin in the blood of cows can be explained by the influence of the components of the preparation on the metabolism of proteins. In cows of the first experimental group, which received the mineral supplement of Sapocorm, there were no probable changes in these indices. The next stage of the work was aimed at studying the effectiveness of preparation for the treatment of sick calves. In the analysis of biochemical parameters, was obtained low effectiveness of control group treatment, which was manifested by a slight increase in the biochemical parameters of the blood of diseased calves, which indicates an ineffective action of preparation. In the treatment of calves in the first group, the general condition was normal within 4–5 days of treatment. This indicates the complex effect of compounds and other elements that are components of the preparation Intecol and probiotic Vetom, on restoring the structure and functions of digestion. An analysis of the biochemical parameters of the blood of the second group when treated with the preparation Intecol and Electrosol oral plagued the normalization of the general state occurred within 2–3 days of treatment. The revealed changes indicate the complex influence of nutrients, which are components of the preparation Electrosol oral. On the basis of the conducted studies, the positive influence of the proposed treatment regimens and the effectiveness of the use of a complex of preparation with the antibiotic “Intecol” has been proved.

scholarly journals Experimental study action autostrains Aerococcus viridans on the model Pseudomonas infection

2017 ◽  
Vol 8 (3) ◽  
pp. 313-316
Author(s):  
D. O. Stepanskyi ◽  
G. M. Kremenchutskyi ◽  
I. P. Koshova
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Clinical Signs ◽  
Solution Concentration ◽  
Control Group ◽  
Infection Model ◽  
Treatment And Prevention ◽  
Aerococcus Viridans ◽  
Group A ◽  
Recovery Dynamics ◽  
Experimental Group

The paper presents the results of a study of the action of Aerococcus autostrains on the model of a chronic blue pus infection. For the study of the action of Aerococcus autosymbiont strains on Pseudomonas aeruginosa, three of the most biochemically and antagonistically active isolates were selected: 1) 5m2015 (isolated from mice); 2) 3k2015 (isolated from rats); 3) 3ch2015 (isolated from humans). Experiments were conducted on 84 white outbred mice weighing 16–17 g, 60 were used as the experimental, and 24 as the control group. In the experimental group of animals, infected wounds were treated by Aerococcus autosymbiont strains once daily (0.2 billion ml–1) till recovery. The drug was administered under the eschar with a syringe. In the control animals the wound was treated by isotonic sodium chloride solution (concentration 0.9%) with the same route of administration and for the same period of time. It was found that from the very first days of application of Aerococci autosymbiont strains, perifocal inflammation was less severe in most animals in the research group compared with the control group. Starting from the fourth day of usage of Aerococcus autosymbiont strains the number of pseudomonades, contained in secretions from wounds in the experimental group of mice was significantly lower than in the control animals. It was revealed that in case of application of Aerococcus strain (5m2015) isolated from mice, the animals had better indicators of recovery, dynamics of local clinical signs of inflammation and the number of pseudomonades contained in the wound in comparison with other Aerococcus autostrains isolated from rats and humans. The wounds purified from pus and covered with dry eschar faster. For example, wounds completely healed with dry eschar rejection by the 11th day of observation in 44 of 58 surviving mice (75.9%). In the control group a similar pattern was observed in only 3 of 17 mice (17.6%) by the that period. The number of Pseudomonas aeruginosa (equivalent to 1 ml of secretions wounds), expressed in logarithms, was 5.00 ± 0.16 on average on the 4th day in the treated mice, while the control group had the same amount of pseudomonades detected in the wounds (lg 5.22 ± 0.38; lg 5.12 ± 0.30) only on the 13–14th days of observation. We found different activity of strains, depending on the origin of microorganism and type host. Aerococcus viridians autosymbionts showed higher rates in the study of their activity in terms of the blue pus infection model in the treatment of the host and lower activity in treatment.of other species. The obtained data may warrant further study of application of Aerococcus autostrains for treatment and prevention of wound infection caused by pseudomonades. 

scholarly journals Hematological parameters and incubation quality of eggs for different levels of tryptophan in the diet of geese of the parent flock

2019 ◽  
Vol 21 (90) ◽  
pp. 104-107
Author(s):  
V. M. Volovich ◽  
S. A. Vovk
Keyword(s):  
Hematological Parameters ◽  
White Blood Cells ◽  
Reproductive Period ◽  
Feed Additives ◽  
Control Group ◽  
Egg Mass ◽  
Synthetic Analogue ◽  
Important Indicator ◽  
Experimental Group

The aim of the work was comparative study of the effect of various amounts of tryptophan in the diet of the herds geese on changes in the parameters of protein metabolism in the blood, their eggs laying capacity and the incubation quality of the eggs, as well as the elimination of herbs and their preservation. The research was carried out during the 4-month reproductive period (December-March) on the gray Obroshino breed group of geese in the research enterprise (SE). The experimental farm (Myklashiv) of the Myklashiv Institute of Agriculture of the Carpathian region of NAAS (Myklashiv village, Pustomytiv district, Lviv region). For this purpose, 4 groups of geese-analogues by age and live weight were selected. The control group did not receive synthetic tryptophan supplements for feed additives. The level of this amino acid in this group amounted to 0.16 g per 100 g of mixed fodder. To the diet of the geese of 2-, 3-, 4-th experimental group additionally injected, respectively, 0.04; 0.09 and 0.14 grams of synthetic tryptophan per 100 g of mixed fodder. The conducted studies have shown that increasing the level of tryptophan in mixed fodders of geese with respect to the norms in force in Ukraine from 0.16 to 0.25 g due to its synthetic analogue per 100 g of mixed fodder during the oviposition period increases the hemoglobin level in the blood by 0.6 g %, white blood cells – by 10.2%, ammonium nitrogen – by 10.5%, stimulates fertility and improves the quality of incubation eggs. While analyzing productivity indices of geese, it should be noted that they were the highest in the 3rd experimental group receiving an additive of 0.09 grams of synthetic tryptophan per 100 grams of mixed fodder. The isolation of the caterpillars was the highest in the 3rd group and amounted to 79.3%. An important indicator, as the egg mass was the largest in the 3rd experimental group and was 172.7 grams or 3.1 g more than in the 1st control geese group. The analysis, namely width and length, shows that the most optimal egg shape index was found in the 3rd experimental group (1.8% higher than in the control group). The thickness of the shell of eggs in the experimental and control groups did not change significantly. It has been experimentally proved that the optimization of tryptophan levels in the feed grain of the gray Obroshin genera of geese in the reproductive period has a significant effect on the hematological parameters and the incubation quality of the eggs.

scholarly journals Influence of the preparation “Bendamin” on the indicators of antioxidant protection of rat myocardium in experimental modeling of heart failure

2019 ◽  
Vol 21 (95) ◽  
pp. 98-101
Author(s):  
I. S. Varkholiak ◽  
B. V. Gutyj
Keyword(s):  
Intraperitoneal Administration ◽  
Clinical Signs ◽  
Free Radical Oxidation ◽  
Feed Additives ◽  
Control Group ◽  
Standard Diet ◽  
Antioxidant Protection ◽  
Diene Conjugates ◽  
Radical Oxidation ◽  
Experimental Group

The aim of this study was to investigate the effect of Bendamin on the antioxidant status of rats in experimental doxorubicin-induced cardiomyopathy. The studies were performed on white sexually mature young male of Vistar line rats weighing 180–200 g, which were kept on a standard diet of the Institute Vivarium of the State Research Institute of Veterinary Drugs and Feed Additives. Animals were divided into 3 groups of 6 animals in each: control group – intact animals; experimental group R1, in which animals were simulated with doxorubicin-induced cardiomyopathy by intraperitoneal administration of doxorubicin at a dose of 2.5 mg/kg 3 times a week for two weeks; experimental group R2, in which animals were injected with the drug “Bendamin” at a dose of 20 mg/kg after injection of doxorubicin. The data obtained indicate that the introduction into the experimental animals of the experimental group of doxorubicin is accompanied by intensification in the myocardium of the processes of free radical oxidation. The increase in diene conjugates was found to be 32.7% and TBK-active products increased by 37.6% compared to the control group of rats. Doxorubicin was also found to cause inhibition of the glutathione system of the animal's antioxidant protection after administration to rats. After administration of the drug “Bendamin”, rats of the second experimental group were suppressed with lipid peroxidation under the conditions of doxorubicin intoxication. In the rats of the second experimental group, the level of intermediates and end products is likely to decrease, so in the rat myocardial homogenate the level of diene conjugates decreased by 16.8% and the level of TBA-active products by 20.8% compared to the first experimental group. who had clinical signs of cardiomyopathy caused by doxorubicin administration. The use of the drug “Bendamin” in rats of the second experimental group contributed to the enhancement of the enzymatic and non-enzymatic element of the antioxidant system, protecting the structural and functional integrity of cell bioembranes. The results of the studies enrich the pharmacological characteristics of the drug “Bendamin”, indicate its sufficiently clear protective effect on the myocardium in experimental doxorubicin cardiomyopathy and is a convincing proof of the feasibility of the drug in veterinary practice.

Sign in / Sign up

Export Citation Format

Share Document