scholarly journals THE CHANGES OF SOME INDICES OF BIOCHEMICAL STATUS IN COWS WITH METABOLIC DISORDERS

2019 ◽  
pp. 62-66
Author(s):  
A. V. Trebukhov ◽  
A. A. Elenshleger
Keyword(s):  
Metabolic Disorders ◽  
Ketone Bodies ◽  
Mineral Metabolism ◽  
Biochemical Study ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Phosphorus Concentration ◽  
Total Calcium ◽  
Before And After ◽  
Apparently Healthy

Under present-day conditions of market economy, the requirements to the quality and quantity of livestock products increase significantly, and this leads to significant intensification of production and, as a consequence, to the development of metabolic disorders including ketosis in highly productive cows. The research goal was to study protein and mineral metabolism in ketotic cows before and after calving. The studies were conducted on the Training Farm «Prigorodnoye» in the City of Barnaul in autumn and winter in comparable Black-Pied cows. Two groups of cows were formed: the trial group consisted of ketotic cows; the control group consisted of apparently healthy cows. These cows underwent clinical and biochemical examination. The biochemical study of blood determined the following: total protein, albumins, alpha-globulins, beta-globulins, gamma-globulins, total calcium, inorganic phosphorus and ketone bodies. The biochemical blood tests were run 4 times: 2 months and 1 month before calving, and in 10 days and in 1 month after calving. It was found that the change of protein metabolism indices in ketotic cows showed a profound disorder of the protein synthesis function of liver both before and after calving. The level of total calcium in the blood of ketotic cows was characterized by lower values as compared to that in healthy comparable cows. At the same time, the dynamics of inorganic phosphorus concentration change did not have significant differences between ketotic and healthy cows. Total calcium content in ketotic cows increased one month before calving while in apparently healthy cows this index increased after calving only. The concentration of ketone bodies in the blood of ketotic cows was significantly higher than that of apparently healthy cows throughout the study.

scholarly journals EFFECT OF FEED ADDITIVE ON MINERAL HOMEOSTASIS OF COWS WITH KETOSIS

2020 ◽  
Vol 21 (1) ◽  
pp. 247-251
Author(s):  
O. Shkilnyk ◽  
I. Petrukh ◽  
D. Ostapiv ◽  
M. Kozak ◽  
V. Vlizlo ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Parathyroid Hormone ◽  
Hormonal Regulation ◽  
Ketone Bodies ◽  
Mineral Metabolism ◽  
Inorganic Phosphorus ◽  
Feed Additives ◽  
Feed Additive ◽  
Total Calcium ◽  
Before And After

The article describes the study of mineral metabolism in patients with cow ketosis and during feeding of our developed feed additive, which includes crushed hop cones, vitamin E and protected from cleavage in the rumen amino acids ˗ methionine, choline and carnitine. In the blood of cows with ketosis, before and after the use of feed additives studied the content of total calcium and inorganic phosphorus, alkaline phosphatase activity, determined the ratio of alkaline phosphatase and total calcium, the concentration of thyroid hormones (parathyroid hormone) and thyroid, thyroid also the amount of ketone bodies in the urine and β-hydroxybutyrate in the blood. It was found that twenty days of feeding cows with ketosis, feed additives leads to a decrease in ketonuria and ketonemia, as well as the normalization of mineral metabolism. At the end of the experiment, the content of total calcium and inorganic phosphorus in the blood of cows increased, the activity of alkaline phosphatase and the ratio of ALP / Ca decreased. The normalization of mineral metabolism in cows was also evidenced by its balanced hormonal regulation. The concentration of parathyroid hormone decreased in the blood plasma and calcitonin increased. According to the results of research, it is established that our proposed feed additive contributes to the normalization of mineral metabolism, and can also be used for prevention and in the complex treatment of cows with ketosis.

scholarly journals Use of “Kayod” Preparation in Cows

2021 ◽  
Author(s):  
Yulia Luschai ◽  
Olga Dutova ◽  
Elena Shaganova ◽  
Irina Pleshakova ◽  
Elena Mashkina
Keyword(s):  
Metabolic Disorders ◽  
White Blood Cells ◽  
Clinical Signs ◽  
Inorganic Phosphorus ◽  
Control Group ◽  
Total Calcium ◽  
Single Use ◽  
Biogeochemical Provinces ◽  
Experimental Group ◽  
Subcutaneous Implant

The Altai territory is an agricultural region; it is a biogeochemical province deficient in iodine. We conducted a study of metabolic disorders in cows that had hypofunction of the thyroid gland. Our research is devoted to the expediency of a single use of the drug “Kayod” administered in the form of a subcutaneous implant in order to normalize the therapeutic status of animals suffering from a chronic lack of iodine in their diet. The purpose of this work is to justify not only the use of the preparation “Kayod” in animals kept in the biogeochemical provinces deficient in iodine, but also the use of tablets administered through a subcutaneous implant. We found a significant increase in the amount of hemoglobin and a decrease in the number of white blood cells in the blood of animals after the use of “Kayod”, and in the second experimental group, these indicators were slightly higher than in the first one. Indicators of the level of total protein and reserve alkalinity of blood were within the limits of physiological norms, but in the experimental groups they were slightly higher than in the control group. The level of total calcium and carotene in the blood of animals in the experimental groups, especially the second, significantly exceeded the level of the same substances in the blood of the animals in the control group. However, the level of inorganic phosphorus tended to decrease. The level of glucose in the blood of cows in the experimental group increased significantly more than in the blood of cows in the control group. This increase was particularly significant in the blood of animals in the second experimental group. When the preparation “Kayod” was used in the form of a subcutaneous implant, there were no clinical signs of hypothyroidism in the cows of the first experimental group after nine weeks. In the cows of the second experimental group, the condition of the cows returned to normal after six weeks. Keywords: Cows, iodine, hypothyroidism, implant, “Kayod

scholarly journals Результати дослідження показників мінерального обміну в крові пацієнтів з ураженням зубів каріозним процесом на фоні ювенільного ревматоїдного артриту

2016 ◽  
Author(s):  
V. M. Kulyhina ◽  
O. Yu. Pylypiuk ◽  
B. Yu. Komnatskyi
Keyword(s):  
Blood Plasma ◽  
Negative Impact ◽  
Mineral Metabolism ◽  
Inorganic Phosphorus ◽  
The State ◽  
Control Group ◽  
Healthy Population ◽  
Total Calcium ◽  
Sick Children

<p>We have defined the main macroelements (Ca, Ca +, P, Mg, K, Na, Cl) in blood plasma of 29 children of the second childhood and 26-children of juvenile age with multiple caries on the background of JRA and in comparison with respectively 25 and 27 children born in the same year from a control group. It was established that the state of mineral metabolism in the blood of sick children is characterized by a significant decrease in total calcium and its ionized faction, and inorganic phosphorus in regard to healthy population of the same age, but within the physiological norm. This went to prove a possible negative impact of accompanying pathology on the state of hard tooth tissues and the role of JRA in the development of multiple cariosity.</p>

Effect of Bhramari pranayama practice on simple reaction time in healthy adolescents – a randomized control trial

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Maheshkumar Kuppusamy ◽  
Dilara Kamaldeen ◽  
Ravishankar Pitani ◽  
Julius Amaldas ◽  
Padmavathi Ramasamy ◽  
...  
Keyword(s):  
Reaction Time ◽  
Cognitive Function ◽  
Simple Reaction Time ◽  
Control Group ◽  
Visual Reaction Time ◽  
Before And After ◽  
Visual Reaction ◽  
Auditory Reaction Time ◽  
Randomized Control ◽  
Apparently Healthy

AbstractObjectivesThe improvement in the/reaction time is important, as it is an indicator of cognitive function. Therefore, there is a need, especially for adolescents in the form of techniques or courses that can improve the reaction time. Yoga was found to cause a better improvement in the health of the individuals. The present study intended to show the effects of Bhramari pranayama (Bhr.P) on reaction time in the healthy adolescents.MethodsOf the 730 potential subjects screened, 520 apparently healthy adolescents randomly assigned to either the Bhr.P group (n-260) or control group (n-260). Bhr.P group practiced the bhramari pranayama for 3 days in a week for 6 months. The Auditory Reaction Time (ART) and the Visual Reaction Time (VRT) were assessed before and after Bhr.P pranayama practice.ResultsBhr.P group shows significant shortening of response time in both VRT (from 267.13 ± 52.65 to 249.87 ± 39.41 ms) and ART (from 237.42 ± 48.12 to 227.91 ± 34.60 ms) after 6 months of Bhr.P practice. In control group subjects, no such significant changes were found (p > 0.05).ConclusionsShortening of RT implies an improvement in the information processing and reflexes. This beneficial effect of Bhr.P on reaction time can be used for improving cognitive function in the adolescents for their academic performances.

scholarly journals State of protein and mineral exchange in broiler-chickens for the use of Zinc and Mangane chelates

2019 ◽  
pp. 85-94
Author(s):  
V. Sakara ◽  
A. Melnyk ◽  
F. Markhenkov
Keyword(s):  
Total Protein ◽  
Broiler Chickens ◽  
Zinc Content ◽  
Calcium Content ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Control Group ◽  
Total Protein Content ◽  
Total Calcium ◽  
Experimental Group

The results of the application of a complex of Zinc and Manganese chelates to protein, macro- and micro-mineral exchanges in the body of broiler chickens of the Cobb 500 cross-breed are presented. The administration of Zn and Mn chelates in a dose of 0,2 ml/l for chicken broilers of 23 days of age (1st experimental group) during 14 days influenced the increase in the total protein content to 35,3±0,8 g/l, which is 8 % higher compared with the control – 32,5±0,7 g/l (p<0,01 ) The concentration of total Calcium in serum of broiler chickens 37-day-old (end of trial) was higher in the first experimental group by 7,3 % (2,05±0,06 mmol/l) compared to control – 1,9±0,03 mmol/l. In the second group, where chelates were administered in a dose of 0,4 ml/l of water, the Calcium content was 2,0±0,02 mmol/l, which is 5 % more than the control group. The two-week application of Zn and Mn chelates also led to an increase in the level of inorganic Phosphorus in the serum of the first group to 2,6±0,12 mmol/l (+ 11,5 %) compared with the control group. After administration of chelates Zn and Mn at doses of 0,2 ml/l water, the Zinc content was higher by 4,3% (23,5±0,2 μmol/l) compared to control – 22,5±0,34 μmol/l (p<0,01). In the second group, where the dose of chelates was 0,4 ml/l, the concentration of Zinc was 23,6±0,16 μmol/l, which is more than 4,6 % for control (p<0,01). At the end of the study, the content of Manganese in serum of broiler chickens in the first group was 1,9±0,07 μmol/l (p<0,05), which is 10,4% higher compared with the control – 1,7±0,06 μmol/l (3rd sampling). The level of this element in the second group was 2,0±0,08 μmol/l (p<0,01), which is higher by 16,7 % relative to the control. At the end of the experiment, the coupon concentration in the first and second experimental groups was 12,6 and 9,3 % higher, compared with control, 7,0±0,37 μmol/l. In turn, the serum Ferrum content of the first group was greater by 9,3 % (19,3±0,69 μmol/l), and the second by 6,7 % (18,8±0,47 μmol/l) compared to the bird of the control group. Key words: chicken broilers, chelates, Zinc, Manganese, Cuprom, Ferrum, metabolism.

scholarly journals CORRECTION OF ANTIOXIDANT SYSTEM STATE IN PATIENTS WITH MICROBIAL ECZEMA

2019 ◽  
Vol 22 (5-6) ◽  
pp. 167-171
Author(s):  
M. M Tlish ◽  
Elena K. Popandopulo
Keyword(s):  
Antioxidant System ◽  
Standard Therapy ◽  
Metabolic Disorders ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Control Group ◽  
System State ◽  
Inflammatory Dermatosis ◽  
Before And After ◽  
Positive Effect

Antioxidant system dysfunction is a significant factor in the pathogenesis of inflammatory dermatosis. Despite an impressive number of studies on the causes and chronization of microbial eczema, the development of a comprehensive approach to therapy taking into account metabolic disorders remains a pressing task. Material and metods. In the course of this study, the effectiveness and expediency of including in microbial eczema therapy a preparation of antioxidant action of dimethyloxobutylphosphonyldimethylate (DFD) was evaluated based on the dynamics of antioxidant system dysfunction indices, markers of syndrome of endogenous intoxication and clinical manifestations. The material for the study was the blood of patients with microbial eczema taken before and after treatment. Dynamics of parameters of enzymatic and non-enzymatic units of antioxidant system dysfunction, level middle mass molecules were analyzed against the background of standard therapy and with inclusion of DFD. Results. Inhibition of antioxidant system dysfunction activity compared to the control group was detected in the blood of all microbial eczema patients prior to treatment. No antioxidant status was observed after the standard therapy course despite achieving clinical improvement. The inclusion of DFD in complex microbial eczema therapy had a positive effect on the state of antioxidant system dysfunction and the dynamics of the skin pathological process.

scholarly journals Biochemical study on immunomodulation and safety margin of inosine acedoben dimepranol before and after vaccination

2019 ◽  
Vol 1 (1) ◽  
pp. 017-025
Author(s):  
Abdel Maksoud Hussein ◽  
Omnia Mahmoud ◽  
Mahmoud Khalifa
Keyword(s):  
Safety Profile ◽  
Broiler Chickens ◽  
Biochemical Study ◽  
Safety Margin ◽  
Control Group ◽  
Immunological Effect ◽  
Before And After ◽  
Biochemical Analyses ◽  
Dose Dependent ◽  
Function Profile

The aim of this study was to evaluate the immunopotentiating effect of IAD in broiler chickens either vaccinated or unvaccinated and to evaluate the safety profile of IAD after treatment with escalating doses. To assess the immunological effect of IAD, eighty chicks were used and divided into four groups. First group kept as control group, second received Isoprinosine (16.3 mg/kg, day after day), third received a routine New Castle disease virus vaccine and the last group received both treatments of Isoprinosine and ND vaccine. The second part of the study aimed to evaluate the safety profile of IAD, to achieve this aim eighty chicks were used, divided equally and given different concentration of IAD 8.15, 16.3, 32.6 mg/kg day after day repetitively. We concluded that, IAD enhanced both nonspecific and specific immune responses in broiler chicken, especially in vaccinated ones, in terms of increased antibody and decreased NDV titers, indicated by HI and PCR, respectively. Also, IAD showed dose-dependent good safety profile, including blood picture, organ function profile and metabolic parameters, indicated by biochemical analyses.

scholarly journals The influence of silicium compounds on the content of calcium, phosphorus and some lipides in the plasma blood

2019 ◽  
Vol 21 (95) ◽  
pp. 41-46 ◽  
Author(s):  
A. I. Ivanitskaya ◽  
Ya. V. Lesyk
Keyword(s):  
Body Weight ◽  
Organic Compound ◽  
Blood Plasma ◽  
Study Groups ◽  
Sodium Metasilicate ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Control Group ◽  
Total Calcium ◽  
Preparatory Period

The aim of the study was to investigate the effects of nanotechnology and sodium metasilicate on the content of total calcium and inorganic phosphorus and individual lipids in the blood of rabbits from 52 to 110 days of life. Studies were conducted on young rabbits of Hyla breed in the private sector. Rabbits for the study were selected at the age of 41 days on the principle of analogues, weighing 1.2–1.4 kg, were divided into six groups (control and five experimental), 6 animals (3 males and 3 females) in each. Animals were kept in with adjustable microclimate and illumination in mesh cages measuring 50×120×30 cm, in accordance with modern animal health standards. The control group rabbits were fed without restriction a balanced granular compound feed, with free access to water. Animals I, II, and III of the study groups were fed a control group diet and fed citrate silicon for 24 hours, with a corresponding rate of 25; 50 and 75 µg Si/kg body weight. Young animals of the IV and V experimental groups were fed wit diet of the control group and water was given sodium metasilicate (Na2SiO3H2O) in the amount of 2.5 and 5.0 mg Si/kg body weight, respectively. The experiment lasted 68 days, including the preparatory period of 10 days, the experimental period – 58 days. In the preparatory period – at 52 days and experimental at 83 and 110 days of life (31 and 58 days of drinking additives) in 4 animals (2 males and 2 females) from the group blood samples were taken for biochemical studies. Studies have found that the concentration of total calcium in the blood plasma of rabbits III and IV study groups was higher by 9.6 and 6.4% (P < 0.05) for 58 days of the study compared with the control, indicating the stimulating effect of the organic compound silicon to activate the processes of assimilation of this macronutrient in the body of young rabbits. Silicone citrate in the large test quantities and sodium metasilicate in the blood plasma of animals of III, IV and V experimental groups respectively increased the level of inorganic phosphorus by 35.7; 28.5 and 35.7% (P < 0.05) than controls at day 58 of the study. In the final study period, the ratio of Calcium to Phosphorus in the animals of the II – V experimental groups was in the range of 2.0–1.73: 1, indicating a more pronounced effect of silicon compounds on the metabolism of Phosphorus during a longer period of supplementation. The content of triacylglycerols in the blood plasma of rabbits II and III of the experimental groups was lower (P < 0.05) at 31 and 58 days of the study compared with the control. The results obtained may indicate the activation of the processes of metabolic accumulation of plastic components of cell membranes and energy needs of body tissues. The use of silica organic compound reduced the cholesterol content by 37% (P < 0.05) in the blood of rabbits of the III experimental group at 31 days of the study. Whereas at the final stage of the experiment in animals II; In the 3rd and 4th research groups, its level was lower by 43.4; 36.9 and 42.2% (P < 0.05) compared to the control, indicating greater use of cholesterol by the organism with silica organic compound.

scholarly journals Yumurtlayan Bıldırcın Rasyonlarına Portakal Kabuğu Yağı İlavesinin Performans, Kabuk Kalitesi ve Bazı Serum Parametreleri Üzerine Etkisi

2020 ◽  
Vol 8 (8) ◽  
pp. 1773-1777
Author(s):  
Behlül Sevim ◽  
Osman Olgun ◽  
Esra Tuğçe Şentürk ◽  
Alp Önder Yıldız
Keyword(s):  
Mineral Metabolism ◽  
Orange Peel ◽  
Cholesterol Concentration ◽  
Control Group ◽  
Phosphorus Concentration ◽  
Eggshell Thickness ◽  
Eggshell Quality ◽  
Orange Peel Oil ◽  
Different Levels ◽  
Peel Oil

The aim of this study is to determine the effects of adding different levels (0, 50, 100, 200, 300 and 400 mg/kg) of orange peel oil to the laying quail diets on performance, eggshell quality and some serum parameters. During the experiment, a total of 120 female Japanese quails at the age of 20 weeks were randomly distributed to 6 treatment groups with 4 replicates, each with 5 quail, for six weeks. The supplementation of different levels orange peel oil to the diets did not affect the performance and eggshell quality parameters, except for eggshell thickness. Eggshell thickness was significantly reduced with the addition of orange peel oil to the diet, and this decrease was more pronounced at the level of 200 mg / kg. Serum glucose, creatinine, albumin, globulin, total protein, ALT and AST concentrations were not affected by orange peel oil. Serum cholesterol concentration considerably declined with the supplementation of 400 mg / kg orange peel oil to the diet. Serum calcium level significantly improved with the addition of 100 and 200 mg / kg orange peel oil to the diet compared to the control group. Additionally, serum phosphorus concentration was considerably increased by 100 mg / kg and more levels orange peel oil. According to these results, it is possible to say that the orange essential oil has the effect of reducing cholesterol at 400 mg / kg and improving mineral metabolism at 100 mg / kg, but this positive effect could not prevent the decrease in eggshell thickness.

scholarly journals Evaluation of parathyroid function and mineral metabolism in psychiatric patients using lithium salts

2014 ◽  
Vol 58 (6) ◽  
pp. 619-624 ◽  
Author(s):  
Thiago Costa de Oliveira ◽  
Ivo Alves de Campos Neto ◽  
Manuel Hermínio de Aguiar-Oliveira ◽  
Francisco de Assis Pereira
Keyword(s):  
Mineral Metabolism ◽  
Psychiatric Patients ◽  
Lithium Carbonate ◽  
Serum Levels ◽  
Inorganic Phosphorus ◽  
Ionized Calcium ◽  
Lithium Salts ◽  
Control Group ◽  
Parathyroid Function ◽  
25 Hydroxy Vitamin D

Objective: To evaluate parathyroid function and mineral metabolism in psychiatric patients users of lithium salts. Materials and methods: We measured the serum levels of calcium, ionized calcium, inorganic phosphorus, alkaline phosphatase, albumin, parathyroid hormone (PTH), urea, creatinine, 25-hydroxy-vitamin D and lithium of 35 patients diagnosed with bipolar disorder in use of lithium carbonate (LC) for at least one year (Lithium Group – LG) and 35 healthy subjects (Control Group – CG). Results: The LG and CG were matched by sex and age. There was only statistic difference in relation to the levels of PTH and ionized calcium, with p < 0.004 and p < 0.03, respectively. Secondary form of hyperparathyroidism (HPT) was found in eight (22.8%) LG patients and in none of the CG. There was no correlation between lithemia, usage time and dosage of LC. Conclusion: Our data demonstrate that lithium may create an imbalance in the parathyroid axis, characterized by elevated levels of PTH.

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