scholarly journals Effectiveness of Gum Arabic in Diabetes and its Complications: A Narrative Review

2021 ◽  
Author(s):  
Suzy Munir Salama ◽  
Hammad Ali Fadlalmola ◽  
Manal Mohammed Abdel Hafeez ◽  
Samia Ali Mohamed Ahmed ◽  
Rafiah Awad Mohamed ◽  
...  
Keyword(s):  
Web Of Science ◽  
Arabian Peninsula ◽  
Kidney Diseases ◽  
Gum Arabic ◽  
Narrative Review ◽  
Advanced Level ◽  
Acacia Species ◽  
English Articles ◽  
Global Health Problem

Gum Arabic (GA) is a gummy exudation from Acacia species, rich in soluble fibers. It is a dietary fiber used traditionally by the natives of many countries of the Arabian Peninsula, Pakistan, and India as therapeutic natural product for treating various diseases including kidney diseases, impotence, obesity, and epilepsy. Diabetes represent a global health problem causing many complications and health risk to people of different ages. The current study aimed at identifying the role of Gum Arabic in treating diseases especially diabetes. Many studies have been conducted on the role of Gum Arabic in experimentally induced diabetes as well as randomized clinical studies. This narrative review was written based on a database search in common libraries such as PubMed, Cochrane, Web of Science, and Scopus. The libraries were searched for English articles published between 1995 and 2020 focusing on the role of Gum Arabic in different preclinical and clinical trials of early and advanced level of diabetes. Keywords: Gum Arabic, diabetes, animals, human, nanoparticles

scholarly journals THE BEST INTERESTS OF THE CHILD: AN INTEGRATIVE REVIEW OF ENGLISH AND PORTUGUESE LITERATURES

2019 ◽  
Vol 24 ◽  
Author(s):  
Josimar Antônio de Alcântara Mendes ◽  
Thomas Ormerod
Keyword(s):  
Web Of Science ◽  
Well Being ◽  
Best Interests ◽  
Google Scholar ◽  
Emotional Needs ◽  
Inclusion Criteria ◽  
Familial Bonds ◽  
English Articles ◽  
Relational Contexts

The best interests of the child (BIC) should be of primary consideration in any situation involving children. Thus, BIC is commonly adopted as a principle, doctrine or test to weight decision-making regarding children. This study consists of an integrative literature review of English and Portuguese publications aimed at investigating how various studies address BIC definitions, characteristics and applications. The inclusion criteria were: 1) articles published between 2012 and 2017, and 2) those clearly addressing a BIC definition, characteristic and/or application. The chosen English databases were ASSIA, PsychARTICLES, PsychInfo, Scopus, Web of Science and Google Scholar; the Portuguese databases were: LILACS, PePsic, Redalyc, Periódicos CAPES and Google Scholar. The main descriptor used was ‘best interests of the child’ which led to 1488 articles being found, and 14 selected. Brazilian articles have focused on the need to protect the child’s physical and psycho-socioemotional well-being, highlighting the child as a subject of rights, and maintaining child’s familial bonds. English articles have broadened the BIC perspective, highlighting the child’s idiosyncrasies, the role of the parent’s interests, and BIC as non-individualistic, flexible and complex. Other results show that BIC is largely related to the child’s development, which is divided into ‘material-physiological’ (basic needs and surviving) and ‘contextual’ (non-material and psychosocial and emotional needs) domains. Overall, BIC is a pluralistic, complex and multi-dimensional construct that depends on the child’s relational contexts.

Trade and 'treasure': the role of Suakin in the movement of valuables (15th–19th centuries)

2020 ◽  
Author(s):  
Lawrence Smith ◽  
Shadia Taha ◽  
Jacke Philips ◽  
Michael Mallinson
Keyword(s):  
Early Modern ◽  
East Asia ◽  
Arabian Peninsula ◽  
Gum Arabic ◽  
Early 20Th Century ◽  
South East Asia ◽  
Archaeological Evidence ◽  
South West ◽  
Indian Ocean Trade

This paper focuses historical and archaeological evidence for the ‘valuables’ passing through Suakin, as part of the Red Sea-Indian Ocean trade. The main locations on Suakin Island Town investigated 2002-2013 are briefly described. Interviews show that at Suakin, in the later 19th century/early 20th century, imported valuables included fabrics from Europe, perfume oils, cloths and wooden chests from India; porcelain from China and Turkey; rugs from Persia/Iran and glass from Italy. Interviews and early modern European accounts indicate the range of products from the hinterland, such as cotton, gold, ivory, ostrich feathers, slaves, horses, gum arabic, ebony, musk, tobacco, rubber and coffee. Local fishermen supplied fish, shells, pearls and mother-of-pearl. The archaeological evidence indicates pottery and porcelain from the Arabian Peninsula, south-west Asia, south Asia, China and south-east Asia, while identifications of wood samples indicates teak from south and south-east Asia. A combination of archaeological, historical and ethnographic evidence is needed to build up a picture of the trade in valuables.

scholarly journals OPIOID-INDUCED HYPERALGESIA IN PATIENTS WITH CHRONIC PAIN SYNDROME OF ONCOLOGICAL GENESIS

2018 ◽  
Vol 23 (2) ◽  
pp. 107-112
Author(s):  
Olga P. Bobrova ◽  
N. A Shnayder ◽  
Yu. A Dykhno ◽  
M. M Petrova
Keyword(s):  
Chronic Pain ◽  
Genetic Factors ◽  
Web Of Science ◽  
Pain Syndrome ◽  
Chronic Pain Syndrome ◽  
Opioid Induced Hyperalgesia ◽  
English Articles

The role of mechanisms of the onset of opioid-induced hyperalgesia in patients with chronic pain syndrome of oncological genesis is highlighted according to the review of results of the search for Russian and English articles in the scientific bases of PubMed, Scopus, Web of Science, eLibrary. The importance of genetic factors predetermining the development of opioid-induced hyperalgesia is shown. The key role of pharmacological preparations for relief of chronic pain in the conditions of opioid-induced hyperalgesia is presented.

scholarly journals The Role of Social Media During the COVID-19 Crisis: A Narrative Review

2021 ◽  
Author(s):  
Mahsa Dalili Shoaei ◽  
Meisam Dastani
Keyword(s):  
Health Care ◽  
Social Networks ◽  
Social Media ◽  
Distance Learning ◽  
Web Of Science ◽  
Narrative Review ◽  
The World ◽  
The Subject ◽  
The Web

In late 2019, the coronavirus 2019 (COVID-19) emerged in Wuhan, China, and rapidly spread around the world. Due to this incident, the use of social networks has increased among people. The present narrative review aimed to investigate the studies conducted on the subject of social media and COVID-19 in the Web of Science database. The investigations show that social media has been used to share viewpoints, health care, and distance learning during the COVID-19 crisis. Therefore, using social media can be a valuable means for the governments and experts to prevent the spread of this epidemic and even in similar future crises.

Social Representations and Commitment

2018 ◽  
Vol 23 (3) ◽  
pp. 233-249 ◽  
Author(s):  
Eric Bonetto ◽  
Fabien Girandola ◽  
Grégory Lo Monaco
Keyword(s):  
Social Representations ◽  
Social Representation ◽  
Second Line ◽  
Review Of The Literature ◽  
First Line ◽  
Research Perspectives ◽  
The Social ◽  
Bibliographic Search ◽  
English Articles

Abstract. This contribution consists of a critical review of the literature about the articulation of two traditionally separated theoretical fields: social representations and commitment. Besides consulting various works and communications, a bibliographic search was carried out (between February and December, 2016) on various databases using the keywords “commitment” and “social representation,” in the singular and in the plural, in French and in English. Articles published in English or in French, that explicitly made reference to both terms, were included. The relations between commitment and social representations are approached according to two approaches or complementary lines. The first line follows the role of commitment in the representational dynamics: how can commitment transform the representations? This articulation gathers most of the work on the topic. The second line envisages the social representations as determinants of commitment procedures: how can these representations influence the effects of commitment procedures? This literature review will identify unexploited tracks, as well as research perspectives for both areas of research.

Biological Role of CDK 11 and 12 in Cell Cycle and its Function in Tumorigenesis

2020 ◽  
Author(s):  
Shamim Mushtaq
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Web Of Science ◽  
The Body ◽  
Main Role ◽  
Hallmarks Of Cancer ◽  
Cyclin Dependent Kinases ◽  
Tumor Studies ◽  
Cycle Regulation

Uninhibited proliferation and abnormal cell cycle regulation are the hallmarks of cancer. The main role of cyclin dependent kinases is to regulate the cell cycle and cell proliferation. These protein kinases are frequently down regulated or up regulated in various cancers. Two CDK family members, CDK 11 and 12, have contradicting views about their roles in different cancers. For example, one study suggests that the CDK 11 isoforms, p58, inhibits growth of breast cancer whereas, the CDK 11 isoform, p110, is highly expressed in breast tumor. Studies regarding CDK 12 show variation of opinion towards different parts of the body, however there is a consensus that upregulation of cdk12 increases the risk of breast cancer. Hence, CDK 11 and CDK 12 need to be analyzed to confirm their mechanism and their role regarding therapeutics, prognostic value, and ethnicity in cancer. This article gives an outline on both CDKs of information known up to date from Medline, PubMed, Google Scholar and Web of Science search engines, which were explored and thirty relevant researches were finalized.

Role of Methylglyoxal in Diabetic Cardiovascular and Kidney Diseases: Insights from Basic Science for Application into Clinical Practice

2018 ◽  
Vol 24 (26) ◽  
pp. 3072-3083 ◽  
Author(s):  
Sowndramalingam Sankaralingam ◽  
Angham Ibrahim ◽  
MD Mizanur Rahman ◽  
Ali H. Eid ◽  
Shankar Munusamy
Keyword(s):  
Therapeutic Strategy ◽  
Kidney Diseases ◽  
Vascular Dysfunction ◽  
Dicarbonyl Compound ◽  
Renal Complications ◽  
Lysine Residues ◽  
Patients With Diabetes ◽  
Prevalence Of Diabetes Mellitus

Background: The incidence and prevalence of diabetes mellitus are increasing globally at alarming rates. Cardiovascular and renal complications are the major cause of morbidity and mortality in patients with diabetes. Methylglyoxal (MG) - a highly reactive dicarbonyl compound – is increased in patients with diabetes and has been implicated to play a detrimental role in the etiology of cardiovascular and renal complications. Derived from glucose, MG binds to arginine and lysine residues in proteins, and the resultant end products serve as surrogate markers of MG generation in vivo. Under normal conditions, MG is detoxified by the enzyme glyoxalase 1 (Glo1), using reduced glutathione as a co-factor. Elevated levels of MG is known to cause endothelial and vascular dysfunction, oxidative stress and atherosclerosis; all of which are risk factors for cardiovascular diseases. Moreover, MG has also been shown to cause pathologic structural alterations and impair kidney function. Conversely, MG scavengers (such as N-acetylcysteine, aminoguanidine or metformin) or Nrf2/Glo1 activators (such as trans-resveratrol / hesperetin) are shown to be useful in preventing MG-induced cardiovascular and renal complications in diabetes. However, clinical evidence supporting the MG lowering properties of these agents are limited and hence, need further investigation. Conclusion: Reducing MG levels directly using scavengers or indirectly via activation of Nrf2/Glo1 may serve as a novel and potent therapeutic strategy to counter the deleterious effects of MG in diabetic complications.

COVID-19 and Comorbidities: is Inflammation the Underlying Condition in Children? A narrative Review

2020 ◽  
Vol 16 ◽  
Author(s):  
Giulia Pinna ◽  
Lavinia Sanfilippo ◽  
Pier Paolo Bassareo ◽  
Vassilios Fanos ◽  
Maria Antonietta Marcialis
Keyword(s):  
Risk Factor ◽  
Severe Form ◽  
Narrative Review ◽  
Underlying Condition ◽  
Pathogenic Mechanisms ◽  
Associated Diseases ◽  
Potential Link

: This paper examines the potential link between COVID-19 and the presence of comorbidities and assesses the role of inflammation in this correlation. In COVID-19 patients, the most frequently associated diseases share a pathogenic inflammatory basis and apparently act as a risk factor in the onset of a more severe form of the disease, particularly in adulthood. However, in children, the understanding of the underlying pathogenic mechanisms is often complicated by the milder symptoms presented. A series of theories have therefore been put forward with a view of providing a better understanding of the role played by inflammation in this dramatic setting. All evidence available to date on this topic is discussed in this review.

The application of virtual reality in health professions� digital education: a narrative review (Preprint)

2018 ◽  
Author(s):  
Lorraine Tudor Car ◽  
Bhone Myint Kyaw ◽  
Josip Car
Keyword(s):  
Virtual Reality ◽  
Professional Education ◽  
Health Professions ◽  
Health Professions Education ◽  
Narrative Review ◽  
Current Evidence ◽  
Future Research ◽  
Educational Content ◽  
Potential Applications

BACKGROUND Digital technology called Virtual Reality (VR) is increasingly employed in health professions’ education. Yet, based on the current evidence, its use is narrowed around a few most applications and disciplines. There is a lack of an overview that would capture the diversity of different VR applications in health professions’ education and inform its use and research. OBJECTIVE This narrative review aims to explore different potential applications of VR in health professions’ education. METHODS The narrative synthesis approach to literature review was used to analyse the existing evidence. RESULTS We outline the role of VR features such as immersion, interactivity and feedback and explain the role of VR devices. Based on the type and scope of educational content VR can represent space, individuals, objects, structures or their combination. Application of VR in medical education encompasses environmental, organ and micro level. Environmental VR focuses on training in relation to health professionals’ environment and human interactions. Organ VR educational content targets primarily human body anatomy; and micro VR microscopic structures at the level of cells, molecules and atoms. We examine how different VR features and health professional education areas match these three VR types. CONCLUSIONS We conclude by highlighting the gaps in the literature and providing suggestions for future research.

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