scholarly journals Dietary Magnesium Intake Modifies the Association Between Vitamin D and Systolic Blood Pressure: Results From NHANES 2007-2014.

Author(s):  
Weichao Huang ◽  
Xiaoman Ma ◽  
Yue Chen ◽  
Jiayi Zheng ◽  
Haojia Li ◽  
...  

Abstract IntroductionAlthough the association between blood pressure and vitamin D has been well studied, the effects of dietary magnesium intake on this relationship are still unclear. Thus, this study aimed to determine the effects of dietary magnesium intake on the association between vitamin D and blood pressure.Research design and methodsThe present study analyzed data from the continuous NHANES 2007-2014. We included 8799 participants aged 20 years or older. Multivariable linear regression was performed to assess the association between vitamin D and systolic blood pressure (SBP), diastolic blood pressure (DBP). Dietary magnesium intake was stratified by low magnesium intake (<299mg/d), high magnesium intake (>=299mg/d). Effect modification by dietary magnesium intake was assessed through interaction tests between vitamin D and SBP in the multivariable linear regression.ResultsIn this cross-sectional study, we found vitamin D was negatively related to SBP, but not to DBP. The relationship between vitamin D and SBP was different in the low and high magnesium intake group (β: -0.18 95%Cl: -0.35-0 vs β: -0.3 95%Cl: -0.51- -0.1). Furthermore, magnesium intake significantly modified the negative relationship between vitamin D and SBP (P value for interaction: 0.026).ConclusionOur research showed that magnesium and vitamin D have an interactive effect in reducing SBP, which may have great importance for clinical medication.

2021 ◽  
Vol 8 ◽  
Author(s):  
Weichao Huang ◽  
Xiaoman Ma ◽  
Hualiang Liang ◽  
Haojia Li ◽  
Jiayu Chen ◽  
...  

Introduction: Circulating vitamin D concentrations have been associated with the risk of type 2 diabetes (T2D). Magnesium has also been reported to be associated with lower T2D risk. Besides, magnesium is an essential cofactor for vitamin D activation. However, the effect of dietary magnesium intake on the association between vitamin D and the risk of T2D has not been studied comprehensively. Therefore, we designed this cross-sectional study to assess the effect modification of magnesium intake on the association between vitamin D and risk of T2D.Research Design and Methods: The present study analyzed data from the National Health and Nutrition Examination Survey (NHANES) continuously from 2007 to 2014, involving 10,249 participants. By having stratified participants based on magnesium intake category (low magnesium intake &lt;267 mg/day; high magnesium intake: ≥267 mg/day), we further evaluated the difference (interaction test) between the relationship of vitamin D with the risk of T2D among low magnesium intake participants and high magnesium intake participants using weighted multivariable logistic regression.Results: In this cross-sectional study, the association of serum vitamin D with the incidence of T2D appeared to differ between the low magnesium intake group and the high magnesium intake group (OR: 0.968, 95%Cl: 0.919–1.02 vs. OR: 0.925, 95%Cl: 0.883–0.97). Furthermore, there was evidence of interaction between vitamin D levels and magnesium intake on decreasing the incidence of T2D (p-value for interaction = 0.001).Conclusions: The results of our study indicated that magnesium intake might affect the association of serum vitamin D with the risk of T2D. Such a finding requires further randomized controlled trials to provide more evidence.


2017 ◽  
Vol 6 (4) ◽  
pp. 385
Author(s):  
Aria Menad M ◽  
Aryu Candra Kusumastuti

Background : Hypertension is one of the degenerative diseases that has high prevalence an increase. One of the factors that influence blood pressure in hypertensive patients is protein, fat, potassium, and magnesium intake. The purpose of this study was to determine the relationship of protein, fat, potassium, and magnesium intake with blood pressure in elderly.Design : This cross-sectional study was conducted among 42 subjects (aged 60-80 years) of PWRI (Persatuan Wredatama Republik Indonesia) members rating South Semarang, Semarang. Food recall method was used to measure the intake of protein, fat, potassium and magnesium intake. Blood pressure was measured with a mercury sphygmomanometer. Rank- Spearman test was used on bivariate analysis. Results : On the results of this study as many as 83.3% of subjects hypertention. Protein intake (52.4% of subjects), fat intake (100% of subject) potassium intake (54.8%) and magnesium (95.2% of subjects) are lower than needs. Bivariate analysis shows that there were no correlation between protein, fat, potassium, and magnesium intake and systolic blood pressure and diastolic blood pressure. Conclusion : In there were correlation between protein, fat, potassium, and magnesium intake and systolic blood pressure and diastolic blood pressure. 


Author(s):  
Prashant Tripathi ◽  
Malvika Mishra ◽  
Kirti Amresh Gautam ◽  
Arisht Jain ◽  
Saurabh Agarwal

Objective: It has been explored that Vitamin D play role in various non-skeletal disorders including Diabetes Mellitus. The present study was designed with the aim to assess association among control, pre-diabetic and diabetic with vitamin D and association between lipid profile and vitamin D. Materials and Methods: A total of 109 subjects were recruited for the cross-sectional study including 37 as control, 41 pre-diabetic and 31 diabetic. A clinical examination was done for all the groups including fasting samples (12hrs) for lipid parameters, serum 25 (OH) vitamin D level and (HbA1/C). Results: It was found that in control subjects 37.9% have the sufficient vitamin D3 level whereas 17.1% subjects in pre-diabetic, 16.6% in diabetic with good glycemic control and no subject was found to have sufficient vitamin D3 level in diabetic with poor glycemic control. The mean vitamin D3 levels was highest in control i.e. -26.53±11.99 ng/ml followed by 20.23±4.12ng/ml in prediabetics,19.07±8.01ng/ml in diabetics with good glycemic control and 12.92±6.77ng/ml in diabetics with poor glycemic control. HBA1/c and serum vitamin D3level share a significant association (P-value< 0.01).Total cholesterol (P-value< 0.0), serum triglyceride (P-value< 0.01), serum LDL cholesterol (P-value< 0.01) and serum VLDL (P-value< 0.01) had inverse association with vitamin D levels. HDL cholesterol has no effect with vitamin D. Conclusion: The present study showed vitamin D3 deficiency as a risk factor for worsening glycemic control and dyslipidemia.


Author(s):  
Asma Abdelaal Abdalla ◽  
Siham Ahmed Balla ◽  
Amna Abdalla Babiker ◽  
Safaa Abdelhameed Medani ◽  
Rania Abdalla Osman Khalfa ◽  
...  

Aims: To measure the waist circumference of Sudanese adults in Khartoum Locality and its relationship to blood pressure and lifestyle  during celebration of international day of hypertension in May 2016 . Study Design: It was a descriptive cross-sectional study. Place of the Celebration: Khartoum Locality at Alsahaa Alkhadraa (The Green Park). Methodology: A total of 364 adult participants, 196 men and 168 women were interviewed using structured questionnaire. Blood pressure (BP) was measured considering hypertension as ≥ 140 mmHg and ≥ 90 mmHg for systole and diastole BP respectively. Waist circumference was measured using an anthropometric measuring tape at cut-off point of 94 cm and 80 cm for men and women respectively. Data was managed by SPSS version 20 and Chi-square test at 95% CL was used to test the association between waist circumference, blood pressure and life style characteristics. Results: Age distribution of the study population showed 48.2% females and 45.4% males in the middle age group (38-57 years). Two thirds of the study population were hypertensive, 62.8% of males and 64.3% of females. The mean waist circumference of men was 97.82 cm + 16.7, mean Systolic BP was 127 + 22 and mean Diastolic BP was 85 + 15. The mean waist circumference of women was 99.31 + 16.2, mean Systolic was 128 + 24 and mean Diastolic BP was 84 +17. Abnormal waist circumference was found in 61.2% of males and 86.9% of females. Fifty nine (30.1%) of the males and 86 (51.2%) of the females with abnormal waist circumference were hypertensive. The association between abnormal waist circumference and high blood pressure was significant among both sexes, P value = 0.001. Physical exercise and fat and salt foods were not significantly associated waist circumference in both men and women. Conclusion: Two thirds of women and men in the celebrating areas were hypertensive.  Half of women and one third of men were significantly hypertensive and having abnormal waist circumference. Doing physical exercise, avoiding fat and salt foods was insignificantly associated with normal waist circumference. Large survey with representative sample is needed to estimate the real Sudanese waist circumference.  


2017 ◽  
Vol 6 (4) ◽  
pp. 313
Author(s):  
Mega Lucyta Sari ◽  
Enny Probosari ◽  
Hartanti Sandi Wijayanti

Background: Hypertension is one of the major risk factors for cardiovascular disease. Decreased intake of omega-3 and increased intake of omega-6 can increase the risk of hypertension. Hypertension cases in Indonesia are highest in women especially aged 30 - 50 years. This study aimed to determine correlation of omega-3 and omega-6 intake with blood pressure in women aged 30-50 years.Method : This was an observational research with cross-sectional study design. Fifty four subjects were selecting using consecutive sampling. Intakes were assessed by food recall 2x24 hours. Blood pressure levels were measured by Sphygmomanometer. Data were analyzed by Chi Square and Fisher Exact.Result : Systolic and diastolic blood pressure mean were 115.92 ± 14.5 mmHg and 75 ± 7.45 mmHg, while omega-3 and omega-6 mean were of 3. 1.03 ± 0.52 g and 14.17 ± 5 , 8 g. More than one third of the subjects (37.9%) with pre-hypertension/hypertension had omega-3 intake less than 1.1 g and 52.7% of them had omega-6 intake less than 12 g.There was correlation of omega-6 intake with systolic blood pressure (p <0.05) but there were no correlation between omega-3 intake with systolic blood pressure, omega-3 and omega-6 intake with diastolic blood pressure (p >0,05). Conclusion: There was correlation of omega-6 intake with systolic blood pressure, there were no correlation between omega-3 intake with systolic blood pressure, omega-3 and omega-6 intake with diastolic blood pressure


2021 ◽  
Vol 12 (2) ◽  
pp. 327
Author(s):  
Ikit Netra Wirakhmi ◽  
Iwan Purnawan

AbstrakLatar belakang: Sampai saat ini, hipertensi masih merupakan tantangan besar di Indonesia. Kepatuhan pasien dalam menggunakan obat berpengaruh terhadap keberhasilan terapi pengobatan. Adanya ketidakpatuhan pasien hipertensi dalam minum obat dapat memberikan efek negative yang sangat besar, seperti munculnya komplikasi. Tujuan: Mengetahui hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi di Puskesmas Karangjambu Kabupaten Purbalingga. Metode: Desain penelitian ini adalah cross sectional study. Responden dalam penelitian ini adalah pasien hipertensi di Puskesmas Karangjambu Kbupaten Purbalingga. Sampel diambil menggunakan teknik accidental sampling dengan jumlah 86 responden. Data dikumpulkan pada bulan Mei 2021 menggunakan kuesioner 8 – Item Morisky Medication Aderence Scale (MMAS – 8) dan pengukuran tekanan darah secara langsung. Hasil: Penelitian ini menunjukkan bahwa Sebagian besar responden adlaah perempuan (86%), sebgain besar berada pada kategori tingkat kepatuhan sedang (47%) dan pada kategori hipertensi tahap 2 (63%). Uji stastistik didapatkan nilai p value 0.901 menunjukkan bahwa tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi. Kesimpulan: Tidak ada hubungan kepatuhan minum obat dengan tekanan darah pada penderita hipertensi AbstractBackground: In Indonesia, hypertension is still a major problem. Adherence to treatment is critical for hypertension patients' long-term health and well-being. Adherence are required for hypertension therapy to be effective, and altering these patients' behavior has the greatest potential for improving hypertensive control. Objectives: To explore the relationship between medication adherence and blood pressure in hypertension patients. Methods: We used the cross-sectional study. This research sample was hypertension patients at Karangjambu Health Centre Purbalingga Regency. We included 89 respondents by accidental sampling technique. We collected the data by questionnaire. The Gamma & Sommers’d test was performed to analyze the data. Results: This research showed that that the majority of respondents were women (86%), the moderate category had the highest level of adherence (47%) and the most respondents suffer from hypertension stage 2 (63%). The statistical test result of 0.910 suggested that there was no relationship between medication adherence and blood pressure in hypertensive patients. Conclusions: There was also no significant between medication adherence and blood pressure. 


2021 ◽  
Vol 1 (1) ◽  
pp. 81-87
Author(s):  
Rista Dwi Pratiwi ◽  
Erti Ikhtiarini Dewi ◽  
Enggal Hadi Kurniyawan

The increase self-regulation learning has an important role related to academic stress management. First-year students are faced with various academic rules and demands that cause first year students to be stressed. This research analyze the correlation between self-regulation learning and academic stress of first-year students of the Faculty of Nursing, University of Jember. This research method is a cross-sectional study of 126 first-year students using cluster random sampling techniques. Bivariate analysis using Kendall tau b correlation (α <0.05 CI = 95%). The research instruments used were Self-Regulated Learning (Cronbach Alpha = 0.864) and Educational Stress Scale for Adolescents (Cronbach Alpha = 0.849). The result of Kendall tau b correlation test results show p-value 0.015 (α < 0.05) and t = - 0.150. This study found that self-regulation learning correlated to academic stress first-year students of the Faculty of Nursing, University of Jember. The correlation results showed a negative relationship direction with very weak strength, the higher self-regulation learning, the lower level of perceived academic stress. From the results and conclusions, researcher hopes that of first-year nursing faculty students can make more efforts to improve self-regulation learning process as an effort to deal with various problems during the lecture period. 


Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4141
Author(s):  
Helena J. Bentil ◽  
Alyssa M. Abreu ◽  
Seth Adu-Afarwuah ◽  
Joseph S. Rossi ◽  
Alison Tovar ◽  
...  

Low magnesium intake has been shown to be associated with an increased risk of type 2 diabetes mellitus (T2DM) in several studies conducted in high-income countries. However, very few studies have been performed in Africa, where many countries have a growing rate of T2DM. We conducted a pilot cross-sectional study among 63 women in Ghana to investigate the association between magnesium intake and glycemic markers. We assessed dietary magnesium using a food frequency questionnaire and glycemic markers using fasting blood glucose and glycated hemoglobin A1c (HbA1c). Our findings showed that the mean magnesium intake was 200 ± 116 mg/day. The prevalence of T2DM was 5% by measuring fasting blood glucose and 8% by measuring HbA1c. Unadjusted linear regression models revealed that higher magnesium intake significantly predicted higher fasting blood glucose levels (β = 0.31; 95% CI: 0.07, 0.55; p = 0.01) and HbA1c levels (β = 0.26; 95% CI: 0.01, 0.51; p = 0.04). In adjusted analyses, magnesium intake was no longer significantly associated with either fasting blood glucose levels (β = 0.22; 95% CI: −0.03, 0.46; p = 0.08) or HbA1c levels (β = 0.15; 95% CI: −0.08, 0.39; p = 0.20). In conclusion, our study did not show a significant association between magnesium intake and glycemic markers in women of reproductive age in Ghana. The results of this study need to be further substantiated because this was the first study to examine magnesium intake and glycemic markers in this population in Africa.


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