scholarly journals QUELLES ETIOLOGIES POUR LINSUFFISANCE RENALE AIGUE DANS LE SERVICE DE NEPHROLOGIE DU CHU DE BRAZZAVILLE?

2021 ◽  
Vol 9 (02) ◽  
pp. 250-255
Author(s):  
Daniel Tony Eyeni Sinomono ◽  
◽  
Celee Mavie Bouloupy-Malanga ◽  
Richard Moukengue Loumingou ◽  
Bertrand Fikahem Ellenga Mbolla ◽  
...  

Context: Acute kidney failure (AKI) is a sudden and reversible deterioration of kidney function. It is of various etiologies which are decisive for its management. Goals: Determine the frequency of AKI determine the types the different stages and aetiologies of AKI in the nephrology service of the university hospital of Brazzaville(UHB). Patients and Methods: This was a retrospective and descriptive study. We reviewed the files of patients hospitalized between January 1, 2016 and October 31, 2020 in the nephrology department of the UHB. Were included, patients aged at least 18 years with a discharge diagnosis of AKI. The study variables were socio-demographic data, stages the type of AKI and the aetiologies. Results: Out of 1,823 hospitalized patients, 244 were hospitalized for an AKI (13.38%), of which 164 had met the inclusion criteria. These were 60.2% boys and 39.8% women, with an average age of 47 ± 19 years. AKI was stage 3 in 69.5%. It was functional in 55.2% of cases with sepsis as the main cause (19.2%) organic (36%) with the main cause of NTA (25.5%) and obstructive in 8.7% of patients. Conclusion: In the nephrology department of the UHB, AKI preferentially affects young adult males. The severe form is common, functional AKI secondary to dehydration or sepsis is the main mechanism of occurrence.

Author(s):  
S. Greten ◽  
J. I. Müller-Funogea ◽  
F. Wegner ◽  
G. U. Höglinger ◽  
N. Simon ◽  
...  

AbstractTo reduce potentially inappropriate medications, the FORTA (Fit fOR The Aged) concept classifies drugs in terms of their suitability for geriatric patients with different labels, namely A (indispensable), B (beneficial), C (questionable), and D (avoid). The aims of our study were to assess the medication appropriateness in PD inpatients applying the FORTA list and drug-drug interaction software, further to assess the adequacy of FORTA list for patients with PD. We retrospectively collected demographic data, comorbidities, laboratory values, and the medication from the discharge letters of 123 geriatric inpatients with PD at the university hospital of Hannover Medical School. Patients suffered on average from 8.2 comorbidities. The majority of the medication was labeled A (60.6% of PD-specific and 40.9% of other medication) or B (22.3% of PD-specific and 26.9% of other medication). Administered drugs labeled with D were amantadine, clozapine, oxazepam, lorazepam, amitriptyline, and clonidine. Overall, 545 interactions were identified, thereof 11.9% severe interactions, and 1.7% contraindicated combinations. 81.3% of patients had at least one moderate or severe interaction. The FORTA list gives rational recommendations for PD-specific and other medication, especially for general practitioners. Considering the demographic characteristics and the common multimorbidity of geriatric PD patients, this study underlines the importance of awareness, education, and preventive interventions to increase drug safety.


Author(s):  
Yıldız Ayanoglu ◽  
Figen Zaif ◽  
Huseyin Abuhanoglu ◽  
Mustafa Genc

The notion of perfectionism, which is defined as a positive notion in terms of meeting predefined standards in a perfect way, paves the way, when not controlled, to determine standards and objectives which can't be fulfilled in no circumstances. Thus, objectives that can't be met result in failures and a deterioration of the state of health of individuals. The very fact that the educators be aware of the perception style of pupils/students in terms of perfectionism and apply education techniques in conformity with these perceptions could be an important factor so that the study and learning level of the students not be affected in a negative manner.This survey is a descriptive study where we tried to evaluate the perceptions about perfectionism of the students who study business administration in the Faculties of Economics and Administrative Sciences in the University of GAZİ and the University of Recep Tayyip Erdoğan. A personal information form containing socio-demographic data and ''Multi-Dimensional Perfectionism Scale'', which was developed by Hewitt and Flett (1991) and translated into Turkish by Oral (1999), were used, respectively, to collect data and survey the perceptions of the said students in terms of perfectionism in this data. The perception of 580 students (370 from GAZİ University and 210 from the University of RecepTayipErdoğan) with regard to perfectionism have been tested and evaluated within the scope of the survey. The outcomes of the survey revealed significant differences, in statistical terms, between the perfectionism determined by others and gender, number of siblings and the location where the family dwells which are the sub-dimensions of perfectionism, and perfectionism directed to others and the educational background of mothers. Keywords: perfectionism, business education


2020 ◽  
Vol 9 (9) ◽  
pp. 3000
Author(s):  
Adam Klocperk ◽  
Marketa Bloomfield ◽  
Zuzana Parackova ◽  
Irena Zentsova ◽  
Petra Vrabcova ◽  
...  

This study aimed to assess the key laboratory features displayed by coronavirus disease 2019 (COVID-19) inpatients that are associated with mild, moderate, severe, and fatal courses of the disease, and through a longitudinal follow-up, to understand the dynamics of the COVID-19 pathophysiology. All severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients admitted to the University Hospital in Motol between March and June 2020 were included in this study. A severe course of COVID-19 was associated with an elevation of proinflammatory markers; an efflux of immature granulocytes into peripheral blood; the activation of CD8 T cells, which infiltrated the lungs; transient liver disease. In particular, the elevation of serum gamma-glutamyl transferase (GGT) and histological signs of cholestasis were highly specific for patients with a severe form of the disease. In contrast, patients with a fatal course of COVID-19 failed to upregulate markers of inflammation, showed discoordination of the immune response, and progressed toward acute kidney failure. COVID-19 is a disease with a multi-organ affinity that is characterized by the activation of innate and cellular adaptive immunity. Biliary lesions with an elevation of GGT and the organ infiltration of interleukin 6 (IL-6)-producing cells are the defining characteristics for patients with the fulminant disease.


2013 ◽  
Vol 59 (4) ◽  
pp. 274-279 ◽  
Author(s):  
T. Biselele ◽  
G. Naulaers ◽  
P. Bunga Muntu ◽  
E. Nkidiaka ◽  
M. Kapepela ◽  
...  

Author(s):  
Henintsoa N. Raveloharimino ◽  
Safidisoa N. Razanamanana ◽  
Lovasoa R. Randriamanga ◽  
N. G. Rasamimanana ◽  
Eudino J. Vonindrazana ◽  
...  

Background: Experiencing a birth with a pathology imposes on parents a lot of frustration. Objectives of this study were to describe the general profiles of newborns and to describe the hospitalization’s psychosomatic impact on parents; in intensive care unit of the neonatalogy ward at the mother-child complex at the university Hospital Androva Mahajanga Madagascar.Methods: It was prospective descriptive study, by a survey of parents, among 3 months, from 01st May to 31th July.Results: Were included 102 newborns. Mains reasons of admission are low birth weigth (51.9%), prematurity (42.1%) and perinatal asphyxia (23.5%). One hundred mothers and 90 fathers had answered our survey. Sleep distturance (all parents), negative feelings (70% of fathers and 75% of mothers), depressed mood (52.2% of fathers and 78% of mothers) and guilt (25.5% of fathers and 58% of mothers) were the most prominent psycological manifestations among parents; then somatic manifestations as digestive, cardiovascular type; weight loss was objectified on 33% of fathers.Conclusions: Newborns’s hospitalization is a difficult situation for parents. Caregivers have an important role in enabling the family to build up.


2021 ◽  
Vol 10 (8) ◽  
pp. e24210817306
Author(s):  
Amanda Francielle Santos ◽  
Josimari Melo de Santana ◽  
Francisco Prado Reis ◽  
José Rodrigo Santos Silva ◽  
Alexrangel Henrique Cruz Santos ◽  
...  

Purpose: Study in order to evaluate the use of complementary and integrative practices for leprosy-related pain. Cross-sectional, descriptive and quantitative research carried out at the University Hospital and Medical Specialties Center of Sergipe between February and June 2019. Methods: 170 people with leprosy pain contributed socio-demographic data, resources used for pain relief and factors that hinder adherence to practices. For pain assessment, the Verbal Pain Scales, Descriptor Scales and the tester Douler Neuropathic 4 were used. Results: Neuropathic pain was present in 119 individuals (70.0%) and the pain was assessed as severe in 85 (50.0%). Half of them (86; 50.6%) reported using pain relief: restricted diet (50, 29.4%), exercise (32, 18.8%), massage (31, 18.2%), among others. The factors that most influenced adherence to practices: lack of information (65, 38.2%), economic reasons (36, 21.2%), subjective characteristics (34, 20.0%). Women (45, 60.0%, p = 0.0427), patients with the borderline clinical form of the patient (23, 74.2%, p = 0.0014), reporting a burning sensation on the skin (70, 55, 5%, p = 0.0437), and those monitored by a physiotherapist (11, 84.6%, p = 0.0178) showed greater adherence to the practices. Conclusion: It is concluded that several complementary and integrative practices are being used for pain relief, but sociodemographic, clinical and care factors can influence adherence to these interventions.


Pathogens ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 851
Author(s):  
Hercules Sakkas ◽  
Christos Kittas ◽  
Georgia Kapnisi ◽  
Efthalia Priavali ◽  
Amalia Kallinteri ◽  
...  

Onychomycosis is considered as one of the major public health problems with a global distribution associated with geographic, demographic and environmental factors, underlying comorbidities and immunodeficiency disorders. This study was conducted to investigate the etiological agents of onychomycosis, in Northwestern Greece during a 7-year period. The study population included 1095 outpatients with clinically suspected onychomycosis that presented to the University Hospital of Ioannina, NW Greece (2011–2017). Samples were examined for causative fungi, and mycological identification was established using standard mycological methods. Demographic data of each patient, comorbidities, localization of infection and history of previous fungal infection were collected. Onychomycosis was diagnosed in 317 of the 1095 suspected cases (28.9%) and the most frequently isolated pathogens were yeasts (50.8%) followed by dermatophytes (36.9%) and non-dermatophyte molds (NDMs) (12.3%). Dermatophytes were mostly involved in toenail onychomycosis (90.6%) and more commonly affected males than females (57.3% vs. 42.7%), while the predominantly isolated pathogen was Τrichophyton rubrum (74.4%) followed by Τrichophyton interdigitale (21.4%). Candida albicans was the most prevalent isolated yeast (82%), whereas among the cases with onychomycosis due to NDMs, Aspergillus spp. were isolated as the principal species (59%). Continuous monitoring should be performed in order to identify possible trends and shifts in species isolation rates and to evaluate the impact of onychomycosis among the general population and high-risk groups.


2011 ◽  
Vol 5 (3) ◽  
pp. 788
Author(s):  
Jonatas Abinadabe Oliveira Silva ◽  
Paulo Affonso Bezerra De Almeida Galeão ◽  
Eliane Maria Ribeiro de Vasconcelos ◽  
Eloine Nascimento de Alencar

ABSTRACTObjective: to evaluate the knowledge about toxoplasmosis along with medical and nursing students. Method: this is about an exploratory and descriptive study, from quantitative approach. Population’s study was composed of academics from the Nursing and Medicine courses, of the Federal University of Pernambuco and of the University of Pernambuco, after meeting inclusion criteria. Data collection was conducted form March to April 2010, using a questionnaire after approval by the Ethics in Research UFPE (protocol number 369/09). Data analysis was performed using the Microsoft Excel and Word ed. 2003 programs, whose presentation of results from absolute and relative, was in figures and tables. Results: fever was the most frequent response, by students as a sign of acute infection (40,8%), 44,7% reported some type of neurological involvement as complication, personal hygiene and/or washing hands in order to prevent reached 20,6%; 57,1% reported IgG and IgM antibodies as diagnostic serological, 40,8% said that the possibility of transmitting toxoplasmosis dog. Conclusion: in general, students did not obtain satisfactory results, showing a little knowledge about several aspects of toxoplasmosis. Descriptors: toxoplasmosis; knowledge; students.RESUMOObjetivo: avaliar o conhecimento sobre a toxoplasmose junto aos estudantes de enfermagem e medicina. Método: estudo exploratório e descritivo, de abordagem quantitativa. A população foi composta por estudantes dos cursos de Enfermagem e Medicina da Universidade Federal de Pernambuco e da Universidade de Pernambuco, após atendimento de critérios de inclusão. A coleta de dados foi realizada entre março e abril de 2010, utilizando-se de questionário após aprovação pelo Comitê de Ética em Pesquisa da UFPE (número de protocolo 369/09). A análise dos dados foi realizada utilizando-se os programas Microsoft Excel e Word ed. 2003, cuja apresentação dos resultados, a partir de números absolutos e relativos, foi em figuras e tabelas. Resultados: febre foi a resposta mais frequente, pelos alunos, como sinal de infecção aguda (40,8%); 44,7% afirmaram algum tipo de acometimento neurológico como complicação; higiene pessoal e/ou lavagem das mãos como forma de prevenção alcançaram 20,6%; 57,1% assinalaram IgG e IgM como diagnóstico sorológico; 40,8% afirmaram que há possibilidade do cão transmitir toxoplasmose. Conclusão: em geral, os estudantes, não obtiveram resultado satisfatório, demonstrando um baixo conhecimento sobre diversos aspectos da toxoplasmose. Descritores: toxoplasmose; conhecimento; estudantes.RESUMENObjetivo: evaluar el conocimiento de la toxoplasmosis junto a los estudiantes de enfermería y medicina. Método: estudio exploratorio y descriptivo, un enfoque cuantitativo. La población estaba compuesta por académicos de la Enfermería y Medicina de la Universidad Federal de Pernambuco y la Universidad de Pernambuco, después de los criterios de inclusión reunión. La recolección de datos se llevó a cabo entre marzo y abril de 2010, mediante un cuestionario tras su aprobación por la Ética en la Investigación UFPE (número de registro 369/09). El análisis de datos se realizó mediante los programas de Microsoft Excel y Word ed 2003, cuya presentación de resultados de absolutos y relativos, fue en figuras y tablas. Resultados: la fiebre fue la respuesta más frecuente, por los estudiantes como un signo de infección aguda (40,8%), el 44,7% reportó algún tipo de afectación neurológica como complicación, la higiene personal y / o el lavado de manos con el fin de evitar que alcanzó 20,6%, 57,1% informó de anticuerpos IgG e IgM en el diagnóstico serológica, el 40,8% dijo que la posibilidad de transmisión de la toxoplasmosis perro. Conclusión: en general, los estudiantes no obtuvieron resultados satisfactorios, mostrando un poco de conocimiento acerca de varios aspectos de la toxoplasmosis. Descriptores: toxoplasmosis; conocimiento; estudiantes.


2021 ◽  
Author(s):  
Johan Courjon ◽  
Julie Contenti ◽  
Elisa Demonchy ◽  
Jacques Levraut ◽  
Pascal Barbry ◽  
...  

AbstractObjectivesThe variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (South East of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this aera. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits.MethodsObservational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n=1247) and those hospitalized in the infectious diseases ward or ICU (n=232). Demographic data, clinical signs and severity were recorded by the NEWS-2, SAPS-2 and SOFA scores were recorded and analyzed.Resultsthe UK-variant was absent in the area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63% to 50% (p=0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p<0.001) while the proportion of patients without comorbidity increased from 16% to 42% (p=0.007). Neither the NEWS-2 score nor the main signs of clinical severity have changed over time.ConclusionSpread of the UK-variant in the South East of France affects younger and healthier patients.


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