Significance to human health of carbamazepine detected in fruits and vegetables irrigated with recycled water

2016 ◽  
Vol 75 (5) ◽  
pp. 1059-1062 ◽  
Author(s):  
Bahman Sheikh

The relevance and significance of the findings of chemicals of emerging concern at nanogram concentrations in recycled water is critically important for the consumers of these crops. The relevance and significance of these chemicals at these concentrations is placed in perspective in terms of the number of years of consumption necessary to accrue one acceptable daily intake every day, over a lifetime, specifically for carbamazepine. In this paper, the number of years is calculated and found to far exceed the maximum human life expectancy, even assuming that the individual consumes a mix of fruits and vegetables irrigated with recycled water throughout an 80-year life span, excluding other food crops free from carbamazepine.

2005 ◽  
Vol 202 (2) ◽  
pp. 197-201 ◽  
Author(s):  
Jean-Laurent Casanova ◽  
Laurent Abel

The immune system's function is to protect against microorganisms, but infection is nonetheless the most frequent cause of death in human history. Until the last century, life expectancy was only ∼25 years. Recent increases in human life span primarily reflect the development of hygiene, vaccines, and anti-infectious drugs, rather than the adjustment of our immune system to coevolving microbes by natural selection. We argue here that most individuals retain a natural vulnerability to infectious diseases, reflecting a great diversity of inborn errors of immunity.


2021 ◽  
Vol 23 (1) ◽  
pp. 22-37
Author(s):  
Aderopo Raphael Adediyan

This study is a contribution to the debate on the significance of financial inclusion with much emphasis on its impacts on human life span. The sample used for the analyses consisted of 14 West African countries over the period 2010 and 2018. The study employed a dynamic 2-Step System GMM approach, and under different model specifications, control for public and private health expenditure, food production quality, population, access to electricity, and the number of people practicing open defecation. The estimated results, among others, showed considerable evidence of positive feedback of financial inclusion on human life span. As such, substantial improvement in the access to and use of financial services is key to a high life expectancy in the region.


2015 ◽  
Vol 8 (3) ◽  
pp. 122 ◽  
Author(s):  
Elena Aleksandrovna Levanova ◽  
Olga Rafailovna Kokorina ◽  
Yuriy Vladimirovich Nikitin ◽  
Tatiyna Vladislavovna Perepelkina ◽  
Polina Anatolievna Segodina

<p>The article describes the theoretical and practical need for the development of the concept of assistance to health protection of the individual in order to address the problem of health protection of students and teachers in the conditions of a higher pedagogical education. The problem of studying human health, its entirety, systemacity and connection with the environment attracts particular attention in recent years. This was one of the reasons to study the problem of “healthy lifestyle” as the qualitative characteristic of a human life aimed at health, due to the fact that a healthy lifestyle is one of the determinants of health. This is made possible with the use of specific health-protecting technologies aimed at searching for ways and means of protection and conservation of health of students and teachers in the conditions of the educational process and using educational tools, which is currently included into the priorities of education.</p>


2007 ◽  
Vol 30 (4) ◽  
pp. 43
Author(s):  
D. Wile

The desire to extend human lifespan has spurred scientific and philosophical interest back to the earliest recorded piece of human literature, the Epic of Gilgamesh, which documents the quest of a mythical king to become immortal. In the intervening years between then and now, and particularly in the last century, human lifespan has increased dramatically. Though it is commonly held that there is an upper biological limit to human lifespan, there are some who believe its recent meteoric rise can continue indefinitely. The story of human lifespan has two largely separate prongs: that of the important advances in sanitation, agriculture and medicine that have effected the greatest change in our life expectancy, and the recurring myth, legend and popular beliefs surrounding greatly advanced or eternal human life. In recent years, the myth and science of life expectancy have coalesced, creating a core group of people who believe that immortality is a technically achievable goal. Such claims have muddied the concept of aging such that it is now commonly described as both a disease process and a fundamental part of life. Hackler C. Extending the life span: Mythic desires and modern dangers. HEC Forum, 2006; 16:182-196. Holliday R. Aging is no longer an unsolved problem in biology. Ann. N.Y. Acad. Sci. 2006; 1067:1-9. Rando TA. Stem cells, ageing and the quest for immortality. Nature 2006; 441:1080-1086.


2019 ◽  
Vol 6 (1) ◽  
pp. 11-16 ◽  
Author(s):  
Amir Hossein Baghaie ◽  
Mohammad Fereydoni

Background: Vegetables are one of the most important components of daily food. Thus, this research was done to evaluate the potential risk of heavy metals on human health due to the consumption of vegetables distributed in the fruits and vegetables central market of Arak, Iran. Methods: In this study, a total 45 samples from edible parts of parsley, mint, chard, fenugreek, cress, basil, coriander, lettuce, and cabbage distributed in the fruits and vegetables central market of Arak were randomly collected and the concentration of heavy metals including lead (Pb), cadmium (Cd), and arsenic (As) in these crop plants was measured using atomic absorption spectrophotometer (AAS). The non-carcinogenic risk of heavy metals intake through the consumption of the studied vegetables was evaluated for male and female using the Environmental Protection Agency (EPA) method. Results: The highest and lowest Pb daily intake and Pb risk index was related to the consumption of cabbage and basil, respectively. And the highest daily intake of Cd and As was related to lettuce consumption, while the lowest daily intake of these metals was related to the consumption of coriander. Among the studied heavy metals, As had the highest hazard quotient (HQ) for non-carcinogenic diseases. The highest HQ belonged to As through lettuce consumption and the lowest one belonged to As through coriander consumption (58 g/day). The HQ for female was higher than that for male. Conclusion: According to the results, the total hazard quotient (THQ) of non-carcinogenic diseases from the total studied vegetables was above the standard level. On the other hand, the HQ for female was higher than that for male.


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Alexandra Sept

AbstractFrom an early age nutrition is part of everyday life, but the motives of eating change over the life span. The nutrition depends on many factors and is always embedded in an individual and social dimension. Especially life-phase-specific framework conditions and factors play an important role in the daily nutrition. The aim of this project was to find out how different factors affect nutritional behaviour in different age groups.The study was part of the research project “enable - healthy food choices in all stages of life”. In order to examine the factors influencing the nutritional behaviour, focus groups with young women and men, middle-agers and elderly had been implemented. In addition biographical interviews were conducted to gain a deeper insight into the reasons for changing the nutritional behaviour. Thus influencing factors and their weighting could be identified and their mode of action could be linked.For example, changes in the nutritional habits of adolescents could be figured out more accurately. Essential for young adults is the replacement of the parents, which is obtained by moving out of the parental home. An own lifestyle and nutritional style has to be developed and there are many changes and new freedoms and opportunities to try out. The consumption of fast food, for example, is particularly attractive to adolescents, as it is a distinction from the adult culture and rules of eating, like eating with cutlery. Another example is the nutritional situation of elderly, which is often characterized by malnutrition or disease-related dietary requirements. However, many elderly do not eat as recommended, even if they have the skills to implement it. In everyday life, deviations from the nutritional recommendations are often legitimized by the age itself “now I can indulge myself a bit”. Other legitimization factors include the death of the partner “I have been cooking my whole life, now I can just eat a sandwich”.The majority of people do not eat according to nutritional recommendations, too much sugar and salt and little fruits and vegetables characterize the nutrition. The consequences do not only concern health aspects such as nutritional diseases, but also ecological aspects. Despite knowing about the consequences of unhealthy food, many do not realize their knowledge about healthy eating in everyday life. If the nutritional situation should be improved sustainably, it is therefore necessary to include the individual factors and changes in the life span in considerations and concepts of nutritional programs.


2021 ◽  
Vol 854 (1) ◽  
pp. 012056
Author(s):  
R Markovic ◽  
M Z Baltic ◽  
S Radulovic ◽  
D Peric ◽  
D Jovanovic ◽  
...  

Abstract In recent times, food is not only observed from the point of view of the required intake for growth, development and regeneration of the body, but also has a leading role in the quality of human life. Therefore, the diet focuses on optimizing the daily intake of both nutrients and non-nutritive ingredients of food, all in order to preserve health and, above all, reduce the risk of chronic non-communicable diseases. Functional food can be considered food that has been scientifically proven to have a positive effect on certain body functions (in addition to the usual nutritional value) that contribute to human health and reduce the risk of disease. At the same time, it is important that the food has a standard form and that the positive effect on health is manifested by consuming the usual amount of food. The functionality of food is achieved by the presence in it of bioactive components (one or more) which have been scientifically proven to have positive effects on human health in the quantities in which they are present in food. The nutritional value of foods of animal origin depends on many factors, but certainly animal diet has the greatest impact. In human nutrition the so-called designed products of animal origin (meat, milk, eggs) are used, which are due to the specific animal diets enriched with n-3 fatty acids, vitamins, carotenoids or trace elements. Today, there are nutritional strategies by which we can access functional foods for the purpose of health promotion.


2013 ◽  
Vol 7 (7) ◽  
pp. 317 ◽  
Author(s):  
Bambang Wispriyono ◽  
Arry Yanuar ◽  
Laila Fitria

Karbamat merupakan salah satu jenis pestisida yang banyak digunakan untuk membasmi hama buah dan sayur. Untuk menentukan bahwa residu karbamat dalam sayuran masih aman dikonsumsi manusia, telah dilakukan analisis beberapa residu karbamat seperti metomil, karbaril, karbofuran, dan propoksur. Sampel-sampel tomat, apel, selada air, kubis, dan sawi hijau dikumpulkan dari tiga supermarket dan satu pasar tradisional di Depok, Jawa Barat. Analisis dilakukan serempak untuk ke empat residu karbamat menggunakan kromatografi cair kinerja tinggi denganpereaksi o-ftalaldehida dan 2-merkaptoetanol dalam reaktor pascakolom dengan detektor fluoresensi. Dari sampel-sampel buah dan sayur yang dianalisis, hanya sawi hijau asal pasar tradisional yang positif mengandung propoksur dengan kadar 1,2 mg/25 gram berat basah (0,048 mg/g berat basah). Dengan Acceptable Daily Intake(ADI) propoksur 0,005 mg/kg berat badan/hari, konsumsi sawi hijau harian seberat 20 g/hari masih cukup aman dari gangguan kesehatan akibat pajanan kronik propoksur dengan margin of safety 298,7 (> 100 sebagai batas aman).Carbamat is a group of pesticides which is commonly used to control fruits and vegetables pests. To determine that carbamat residues in fruits and vegetables are safe for human consumption, carbamate residues such as methomyl, carbaryl, carbofuran, and propoxur in vegetables and fruits have been analyzed. Samples of tomato, apple, water lettuces, cabbage, and mustard greens were collected from three supermarkets and one traditional market in Depok, West Java. The analysis was carried out simultaneously for all four carbamate residues by high performance liquid chromatography using o-phtaladehyde and 2 mercaptoethanol reagents in post-column reactor with a fluorescence detector. Of fruits and vegetable samples analyzed, only mustard greens from traditional market positively containe propoxur at 1.2 mg/ 25 gram wet weight (0,048 mg/gram wet weight). With Acceptable Daily Intake (ADI) of 0.005 mg/kg body weight/day, mustard greens consumption of 20 g/day is safe from adverse health effect from chronic exposure to propoxur with Margin of Safety of 298.7 (> 100 as safe limit).


2021 ◽  
pp. 199-202
Author(s):  
D.A. Pipoyan ◽  
M.R. Beglaryan ◽  
G.K. Gharibyan ◽  
A.A. Aghababyan

This research sets out to assess both the antibiotic exposure via milk produced in the Republic of Armenia and the associated human health risks. As established, the milk of domestic production contains residual antibiotics (streptomycin, chloramphenicol, tetracyclines). The estimated daily intake (EDI) and the margin of exposure (MOE) for the antibiotics identified upon this research were assessed. It has been indicated that for the population of Yerevan, the daily intake of antibiotics via milk does not exceed the acceptable daily intake (ADI). Moreover, the derived MOE values point to the absence of health risks associated with shop-bought milk.


2020 ◽  
Vol 22 (11) ◽  
pp. 16-19
Author(s):  
Obukhova K.A. ◽  
Ponomareva L.I. ◽  
Gan N.Yu.

The article is devoted to a topic that has not been sufficiently studied in domestic and foreign literature - a philosophical understanding of the phenomenon of health in the historical and modern contexts of the development of knowledge. This understanding takes into account the diversity of forms of physical, mental and social conditions of a person. Also, in this work, a comparative analysis of the justification of health in various evolutionary-historical, cultural and philosophical interpretations is carried out. In the article, the authors have shown the promise of using "the floors of our health" (according to Yu.A. Andreev) for a philosophical presentation of modern concepts of human health. The aim of the research is a philosophical presentation of modern concepts of health. Preservation and maintenance of health is one of the fundamental values of human life. Despite this, a number of issues remain unresolved that are essential for the study of problems related to human health. Therefore, the article presents an attempt to outline and analyze a wide range of different views and ideas about the health problem. The increasing importance of philosophy of health in solving practical problems of physical and spiritual development of a person in the era of industrialism is shown. In addition, the authors highlight the importance and relevance of the problem of a person's awareness, their needs, their attitude to health at any stage of personality development. The authors revealed the connection between the deterioration of health and the occurrence of diseases with the development of mankind, the predominance of the physical over the spiritual, the material over the moral, the progress of the technogenic world. Although from a spiritual point of view, diseases, under certain conditions, can become a source of positive spiritual experience, which is of great importance for the individual.


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