Use of the genus Satureja as food supplement: possible modulation of the immune system via intestinal microbiota during SARS-CoV-2 infection?

2021 ◽  
Vol 20 ◽  
Author(s):  
Abdelkarim Ezaouine ◽  
Badreddine Nouadi ◽  
Yousra Sbaoui ◽  
Mariam El Messal ◽  
Fatima Chegdani ◽  
...  
Keyword(s):  
Immune System ◽  
Intestinal Microbiota ◽  
Viral Infections ◽  
Biological Activities ◽  
Food Supplement ◽  
Traditional Use ◽  
The World ◽  
Causes Of Disease ◽  
Potential Impact ◽  
Antibacterial And Antifungal

Abstract: Satureja genus belongs to the Lamiaceae family, they are used in food products and by pharmaceutical and cosmetic industries. The chemical composition of Satureja are responsible for its pharmacological and phytochemical properties. Among the various biological activities, notably antioxidant, antibacterial and antifungal, Satureja also has a potential antiviral activity. The existence of a microbiota modulation potential by Satureja in farming animals has also been reported. Viral pathologies are one of the main causes of disease in the world. It is commonly known that gut microbiota plays a crucial role in the fight and progression of viral infection. Previous studies conducted on coronavirus disease 2019 (COVID-19) pandemic have prouved an imbalance in the intestinal and pulmonary microbiota via gut-lung axis. Knowing the properties of Satureja and its traditional use, one can suggest the possibility of using it as dietary supplement to modulate immune system in order to prevent and fight viral infections. The objective of this review is to reveal the potential impact of medicinal plants such as Satureja genus as food supplement, on immune enhancing during SARS-CoV-2 infection and their relationships with the intestinal microbiota.

scholarly journals Lichens: traditional use and biological activities

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Ruchira R. Sutar ◽  
◽  
Subhash B. Gaikwad ◽  
Sachin V. Mapari ◽  
Bhaskar C. Behera ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Traditional Knowledge ◽  
Metabolic Pathways ◽  
Biological Activities ◽  
Lichen Species ◽  
Symbiotic Association ◽  
Traditional Use ◽  
Rich Diversity ◽  
The World ◽  
Immense Potential

Lichens are a stable symbiotic association between photobiont (algae and/or cyanobacteria) and mycobiont (fungi). They are utilized in traditional medicine for ages and documented in various pharmacopeia throughout the world. India is having a rich diversity of lichen species represented by about 2400 species. The tribal inhabitant around forests and other difficult terrains acquired unique knowledge about the use of much wide flora and fauna. Most of these are either lesser known or unknown to the outside world. The treasure of traditional knowledge if subjected to scientific scrutiny could benefit humankind in many ways. They produce unique secondary metabolites through various metabolic pathways and are known to exhibit a wide array of bioactivities. We have reviewed the literature for traditional knowledge of the lichen species and biological activities reported to study its inter-relationship. It was observed that that still a major percentage of lichens have remained unexplored. These lichens may have immense potential; and if analysed could be used in pharmaceutical, nutraceutical, cosmetic industries, and many more.

Reasons for discontinuing the use of Hydroxychloroquine in the treatment of the Novel Coronavirus

2021 ◽  
pp. 179-180
Author(s):  
Ali Adel Dawood
Keyword(s):  
Immune System ◽  
Viral Infections ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus

In March 2020 the world officially released its first approach to the coronaviral pandemic to explain the rationale for using hydroxychloroquine. It was also believed to calm down the immune system during viral infections. The FDA warned using hydroxychloroquien for SARS-CoV-2. In this short letter we address why the FDA discontinued the treatment of the novel coronavirus with hydroxychloroquine.

scholarly journals The Effect of Nanogold-Nanosilver to Increase the Immunity of People Affected by COVID-19 with Hypertension Comorbidities

2021 ◽  
Vol 04 (07) ◽  
Author(s):  
Amelia Putri Divindha ◽  
Keyword(s):  
Silver Nanoparticles ◽  
Immune System ◽  
Viral Infections ◽  
Health Sector ◽  
The Body ◽  
P Value ◽  
Gold And Silver Nanoparticles ◽  
The World ◽  
Leprosy Patients ◽  
Paired T Test

The SARS‐CoV‐ 2/Covid-19 Coronavirus is currently endemic throughout the world. The comorbidities of Covid-19 with the highest percentage reaching 50.5% are hypertension. Hypertension included in Non-Communicable Diseases (NCD) is generally chronic. It can reduce the sufferer’s immune system gradually and is very susceptible to infections, including those caused by viral infections, one of which is the SARS-CoV-2 virus or commonly called COVID-19. Therefore, patients with NCD, especially hypertension, are encouraged to increase immunity and body immunity to avoid virus infection. Currently, nanoparticles, especially Nanogold and Nanosilver, are taking place very rapidly in the health sector because gold and silver nanoparticles have various benefits such as antioxidants, antivirals, and antibacterials. After being proven effective in dealing with leprosy patients in Surabaya, especially in terms of increasing immunity. Now Nanogold-Nanosilver was developed with the hope to help relieve Covid-19 sufferers through increasing the body’s immune system because if the body’s immune system decreases, the virus will quickly enter the body. In this study, Nanogold and Nanosilver were developed into a health water drink that volunteers can drink every day. Volunteers are people affected by Covid-19 in the Karanganyar area of Surabaya. This study uses a one-group pretest-posttest design. The data collection is carried out through direct observation and interviews with people affected by Covid-19 regularly every week. Then the data analysed using a paired T-test on the SPSS application. And obtained a P-value of 0.000, which means that there is an effect of nanogold-nanosilver for increase body immunity.

scholarly journals Importance of functional nutrition components on new Coronavirus disease (COVID-19) and other viral communicable diseases

2021 ◽  
Vol 7 (4) ◽  
pp. 286-299
Author(s):  
Serhan Mohammed ◽  
Nigün Özdemir ◽  
Ahmet Hilmi Çon
Keyword(s):  
Immune System ◽  
Human Health ◽  
Intestinal Microbiota ◽  
Viral Infections ◽  
Communicable Diseases ◽  
Bioactive Components ◽  
Human Immune System ◽  
Human Immune

There are no foods to prevent or treat the coronavirus alone; however, it has been proven that a healthy and balanced nutrition is crucial for health, particularly in times when the immune system might need to fight back. The present study provides insights about the properties of bioactive components of foods and herbs as a possible adjuvant support the human immune system against infections. Also, has focused on the interactions of the intestinal microbiota with human health in the treatment of Covid-19 and other viral infections. More research with strong recommendations is needed to better understand causality.

scholarly journals Can trace element supplementations (Cu, Se, and Zn) enhance human immunity against COVID-19 and its new variants?

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Bouzid Nedjimi
Keyword(s):  
Immune System ◽  
Trace Element ◽  
Viral Infections ◽  
Immune Defense ◽  
Main Body ◽  
Human Immune System ◽  
The World ◽  
Human Immunity ◽  
The Individual ◽  
Probable Relation

Abstract Background Coronavirus-19 (SARS-CoV-2) is constantly changed through mutation, and new stains of this virus are detected throughout the world such as B.1.1.7 (UK), B.1.351 (South Africa), and P.1 (Brazil). These strains seem to be more easily transmissible than other variants, which may lead to more cases and more deaths. Currently, there are many vaccines for SARS-CoV-2 available in the market but without full clinical data beside. Despite the existence of these vaccines, the numbers of outpatients are still increasing in many countries around the world, and the reliability of these vaccines still remains elusive. It is well known that trace element deficiencies increase the individual susceptibility to immune dysfunction and lead to global health problem. In this context, improving the immune defense system to combats this pandemic is absolutely necessary. The purpose of this review is to establish the probable relation between trace elements supplementation and COVID-19. Main body Several clinical studies confirmed that Cu, Se, and Zn insufficiencies alter the immune system and increase the vulnerability to viral infections. Based on antiviral and anti-inflammatory effects of these micronutrients, it seems logical that dietary supplementations of these components might enhance human immune system and lower the graveness of COVID-19 infection. Conclusion Based on available data, we hypothesize that the clinical use of some essential trace element supplementations such as copper, selenium, and zinc might be a preventive and promising option to enhance human immunity against the new pandemic COVID-19 and its new strains. Graphical abstract

scholarly journals WAY TO LIVE WITH COVID-19

2021 ◽  
pp. 41-41
Author(s):  
Sann Sanda Khin
Keyword(s):  
Developing Countries ◽  
Immune System ◽  
Southeast Asia ◽  
Vaccination Coverage ◽  
Viral Infections ◽  
Environmental Adaptation ◽  
Mutation Rates ◽  
World Population ◽  
The World ◽  
Travel Restriction

Nobody knows what will be in future during COVID-19 delta surge and appearance of new Mu variant of COVID-19. But, everyone hopes the pandemic will end soon. The recent and current rising trend in cases and deaths not only in Southeast Asia region but also around the world warns that any travel restriction must be necessary to conduct.If people gain some immunity through either vaccination or infection, it will change into endemic stage. Unfortunately, vaccination coverage is not so high compared with world population. Thus, local people living in developing countries face the COVID-19 delta surge by fighting against with only naïve immune system. SARS-CoV-2, which is responsible for COVID-19 infection, is a novel emerging contagious agent that has found a way into human civilization. Generally, emerging and reemerging of viral infections belong to the RNA family of viruses since these viruses have high mutation rates that allow their eminent environmental adaptation with rapid evolution.Up to date,little knowledge is available about SARS-Co V-2 (1,2).

scholarly journals A CRITICAL APPRAISAL ON IMMUNOMODULATION AND BATTLE AGAINST COVID-19: AN EVIDENCE BASED PREVENTIVE AYURVEDIC APPROACH

AYUSHDHARA ◽  
2020 ◽  
pp. 2656-2670
Author(s):  
Masand Sameet ◽  
Thakur Jyotsna
Keyword(s):  
Viral Infections ◽  
Vaccine Development ◽  
Biological Activities ◽  
Time Lag ◽  
Effective Vaccine ◽  
Evidence Based ◽  
Positive Health ◽  
Highly Pathogenic ◽  
The World ◽  
Prohibitive Cost

The emergence of SARSCOV-2 has been noticed as the third introduction of a highly pathogenic corona virus into the human population after SARS-COV and MERV-COV in 21st century. It has posed a horrible situation that warrants urgent global attention due to the emergence of more virulent viral strain, predicted future viral mutations, prohibitive cost of available drugs, time lag between vaccine development and mass causalities occurring all over the world. Although specific antiviral vaccine is the effective solution but a potent and comprehensive immune response to maintain homeostasis is also critical for prophylactic as well as therapeutic management of the disease. Amidst all the gloom spread due to this outbreak, everyone is focusing on preventive measures until an effective vaccine is developed. Ayurveda- An holistic science offers a plethora of preventive therapies to enhance body’s resistance against infections. It is evident that nutritional and herbal approaches taken together provide potent tools for controlling an array of viral infections and have been effectively used by humans all over the world since ages during such outbreaks. Ayurveda and yoga have great potential for embracing the world in creating a more positive health abode. Herbs exhibit a diverse array of biological activities and can be effectively harnessed for managing this pandemic. This review portrays an eclectic overview for the preventive management of COVID-19 pandemic covering the dietary, lifestyle and herbal evidence based approaches that may be most likely helpful in managing the current pandemic scenario and also strengthens our body to cope-up with the next pandemic that might appear in not too distant future.

scholarly journals Treatment of urinary tract infections with medicinal plants: Monographs of some plants species revealed by traditherapists

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Victorien Dougnon ◽  
Phénix Assogba ◽  
Hornel Koudokpon ◽  
Césaire Ayena ◽  
Sosthéne Vissoh ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Medicinal Plants ◽  
Urinary Tract Infections ◽  
Viral Infections ◽  
Skin Diseases ◽  
Scientific Evidence ◽  
Traditional Use ◽  
Suitable Alternative ◽  
The World ◽  
Tract Infections

Medicinal plants are a precious heritage for humanity and especially for the majority of poor communities in developing countries who depend on them for primary health care and livelihoods. They are used in traditional practices against urinary tract infections without any scientific evidence for most of the species used. This work aims to have a summary of the literature on some medicinal plants used in the treatment of urinary tract infections. To do this, this study was carried out based on the different medicinal plants cited by herbalists in southern Togo against urinary tract infections. The names of these different plants have each been the subject of research with keywords in search engines such as Google Scholar, PubMed, FreefullPdf, and others to bring out the traditional use of these plants in the world. From all of the above, it appears that the medicinal plant species cited by actors of the Togolese pharmacopoeia are used to treat several diseases in the world. The organs of these plants, such as leaves, bark, and roots are used in the treatment of common illnesses such as typhoid fever, diarrhea, malaria, bronchitis, and hypofertility. Coughs, colds, skin diseases, toothache, gonorrhoea, viral infections, and many other diseases are treated with these plants. The plants are often combined with other plants in traditional medicine. They are used in the form of decoction, fumigation, herbal tea, and others. The type of disease treated by the plants changes from region to region and is also dependent on the culture of the region in the world. The use of medicinal plants is a very ancient practice. It is a very suitable alternative to modern medicine. However, there is a need to have more detailed studies on these plants, such as their toxicological effects.

scholarly journals Comment on “Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections. Nutrients 2020, 12, 1181”

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2321
Author(s):  
Alexandros Tsoupras ◽  
Ioannis Zabetakis
Keyword(s):  
Immune System ◽  
Severe Acute Respiratory Syndrome ◽  
Nutritional Status ◽  
Viral Infections ◽  
The Novel ◽  
The World ◽  
Novel Coronavirus

The novel coronavirus (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has engulfed the world since December 2019 [...]

Role of Rasayana in Prevention of COVID-19 - A Review

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 716-722
Author(s):  
Sneha Dhakite ◽  
Sadhana Misar Wajpeyi
Keyword(s):  
Immune System ◽  
Respiratory System ◽  
Viral Infections ◽  
Cost Effective ◽  
The Body ◽  
Healthy Life ◽  
Vital Functions ◽  
Healthy Life Style ◽  
And Control

The “Coronavirus disease 19 (COVID-19)” is caused by “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)”, a newly discovered member of the Coronaviridae family of viruses which is a highly communicable. There is no effective medical treatment till date for Coronavirus disease hence prevention is the best way to keep disease away. Rasayana proved to be highly efficacious and cost effective for the Prevention and Control of viral infections when vaccines and standard therapies are lacking. Rasayana Chikitsa is one of the eight branches of Ashtanga Ayurveda which helps to maintain healthy life style. Rasayana improves immunity and performs many vital functions of human body. Vyadhikshamatva that is immune mechanism of the body is involved in Prevention of the occurrence of a new disease and it also decreases the virulence and progression of an existing disease. In COVID-19 the Respiratory system mainly get affected which is evident from its symptoms like cold, cough and breathlessness. Here the drugs help in enhancing immune system and strengthening functions of Respiratory system can be useful. For this purpose, the Rasayana like Chyavanprasha, Agastya Haritaki, Pippali Rasayana, Guduchi, Yashtimadhu, Haridra, Ashwagandha, Tulsi are used. Rasayana working on Respiratory system are best for Prevention of Coronavirus and boosting immune system. Rasayana Chikitsa can be effective in the Prevention as well as reducing symptoms of COVID-19.

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