Estimation of the efficiency of measures of correction of the functional state of the cardiovascular system of operators of deep water technical means during the course of the voyage

2021 ◽  
Vol 7 (3) ◽  
pp. 20-31
Author(s):  
Yu. R. Khankevich ◽  
K. V. Sapozhnikov ◽  
D. V. Cherkashin ◽  
G. G. Kutelev ◽  
S. A. Parfenov ◽  
...  

During the course of the voyage, divers experience the effect of the wide range of adverse factors of operator labor and ship's habitability.The objective of the study is to estimate the state of cardiovascular system of operators of deep water technical means after using the complex of measures aimed at correction of function al state of operators during the course of the voyage.Materials and methods. The study was conducted with the participation of 38 operators of deep water technical means from among the crew of nuclear submarine engaged in operator labor activity. The study was performed twice: before the voyage and after return to base and included: cardiorhythmogram and psychophysiological study methodologies of functional state. Patients were divided into two groups: main (n = 13) and control (n = 25).Results and discussion. The control group shows sympathicotonia (reducing heart rate variability, intensity of respiratory arrhythmia). The main group, on the contrary, shows relative balance of regulatory systems. Thus, the conducted assessment of the state of cardiovascular system showed positive effects of using the complex of measures aimed at correction of functional state of operators during the course of the voyage.

Author(s):  
М. М Матлубов ◽  
А. А. Семенихин ◽  
С. А Рузибаев ◽  
Н. И Закирова ◽  
О. В Ким

СОСТОЯНИЕ ГЕМОДИНАМИКИ У БЕРЕМЕННЫХ С ОЖИРЕНИЕМ - В данной статье представлены изменения состояния гемодинамики у беременных с ожирением при неосложнённой беременности. В исследование включены результаты комплексного обследования 84 беременных в возрасте от 23 до 28 лет с ожирением различной степени выраженности при сроках гестации 36-38 недель. В контрольную группу вошла 21 беременная аналогичного возраста и срока гестации с нормальной массой тела. У всех наблюдаемых пациентов беременность согласно консультациям акушер-гинекологов была признана неосложнённой. Степень ожирения оценивали по индексу массы тела. Проведённое исследование показало, что избыточный вес тела по мере её прогрессирования оказывает крайне неблагоприятное влияние на гемодинамику и функциональное состояние сердечно-сосудистой системы в целом, снижает коронарные резервы. Наиболее выраженные нарушения функционального состояния сердечно-сосудистой системы имеют место при ожирении II и III степеней.<br />СТАН ГЕМОДИНАМІКИ У ВАГІТНИХ З ОЖИРІННЯМ - Уданій статті представлено зміни стану гемодинаміки у вагітних з ожирінням при неускладненій вагітності. У дослідження включені результати комплексного обстеження 84 вагітних у віці від 23 до 28 років з ожирінням різного ступеня вираження при термінах гестації 36-38 тижнів. У контрольну групу ввійшла 21 вагітна аналогічного віку та терміну гестації з нормальною масою тіла. У всіх спостережуваних пацієнтів вагітність згідно з консультаціями акушер-гінекологів була визнана неусклад- неною. Ступінь ожиріння оцінювали за індексом маси тіла. Проведене дослідження показало, що надлишкова маса тіла в міру її прогресування украй несприятливо впливає на гемо- динаміку і функціональний стан серцево-судинної системи в цілому, знижує коронарні резерви. Найбільш виражені порушення функціонального стану серцево-судинної системи мають місце при ожирінні II і III ступенів.<br />HEMODYNAMIC STATUS OF PREGNANT WOMEN WITH OBESITY - In this article are represented the changes in hemodynamic status of pregnant women with obesity in uncomplicated pregnancy. In the study was included the full survey results of 84 pregnant women aged between 23 and 28 years with obesity of varying severity at 36-38 weeks gestation. The control group included 21 pregnant women of similar age and gestational age with normal body weight. All observed patients, pregnancy according obstetrical consultation was recognized uncomplicated. The degree of obesity was assessed by body mass index. Researchers conducted showed that overweight as its progression has a very adverse effect on hemodynamics and functional state of the cardiovascular system as a whole, reduces coronary reserve. The most pronounced violation of the functional state of the cardiovascular system occurs in obesity 2nd and 3rd degree.<br />Ключевые слова: беременность, ожирение, гемодинамика.<br />Ключові слова: вагітність, ожиріння, гемодинаміка


2020 ◽  
Vol 21 (18) ◽  
pp. 6740
Author(s):  
Aleksandra Kicman ◽  
Marek Toczek

Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis which exhibits potential beneficial properties in a wide range of diseases, including cardiovascular disorders. Due to its complex mechanism of action, CBD may affect the cardiovascular system in different ways. Thus, we reviewed the influence of CBD on this system in health and disease to determine the potential risk of cardiovascular side effects during CBD use for medical and wellness purposes and to elucidate its therapeutic potential in cardiovascular diseases. Administration of CBD to healthy volunteers or animals usually does not markedly affect hemodynamic parameters. Although CBD has been found to exhibit vasodilatory and antioxidant properties in hypertension, it has not affected blood pressure in hypertensive animals. Hypotensive action of CBD has been mainly revealed under stress conditions. Many positive effects of CBD have been observed in experimental models of heart diseases (myocardial infarction, cardiomyopathy, myocarditis), stroke, neonatal hypoxic ischemic encephalopathy, sepsis-related encephalitis, cardiovascular complications of diabetes, and ischemia/reperfusion injures of liver and kidneys. In these pathological conditions CBD decreased organ damage and dysfunction, oxidative and nitrative stress, inflammatory processes and apoptosis, among others. Nevertheless, further clinical research is needed to recommend the use of CBD in the treatment of cardiovascular diseases.


2020 ◽  
Vol 33 (5) ◽  
pp. 777-783
Author(s):  
Marta Skowron ◽  
Jerzy Kociuga ◽  
Marcin Domzalski

BACKGROUND: There is a wide range of rehabilitation protocols after knee arthroscopic procedures, mainly based on specialist exercises. They comprise of specific stages and key moments but should also be individualized and adjusted to the patient’s needs. OBJECTIVE: The aim of the study was to evaluate the BodyFlow device impact on physical and psychological functioning of the subjects after knee arthroscopy. METHODS: Ninety three patients were randomly divided into the study and control group. Each study group subject performed mild electrostimulation using the BodyFlow device for three weeks, five times a day for 20 minutes along with the standard rehabilitation protocol. Control group subjects were treated according to the standard rehabilitation protocol after knee arthroscopy. Healthy and operated lower limb size, a range of the knee joint motion, and the flexor and extensor strength were measured 3, 6, and 9 weeks after arthroscopy. At each measurement, the SF-36 and KOOS surveys were collected. RESULTS: On study day 21, a positive, statistically significant, difference in the knee joint size, range of flection and extension, flexor and extensor strength as well as all KOOS survey subscales and physical functioning categories included in the SF-36 survey was observed. On study day 63, positive effects persisted and significant differences in other categories included in the SF-36 survey were observed. CONCLUSION: Application of mild electrostimulation using the BodyFlow device has a positive impact on the swelling in the knee joint region, range of motion, extensor and flexor strength as well as physical, psychological, and social functioning.


Author(s):  
O.A. Shaposhnyk ◽  
V.M. Sokolenko ◽  
N.S. Kopyt’ko ◽  
T.I. Shevchenko ◽  
I.P. Kudrya

A variety of factors influence the performance of schoolchildren. The main factors are psycho-emotional stress and systematic physical activity that requires a constant tension of body's regulatory systems aimed at mobilizing the functional body reserves. The analysis of blood pressure enables to estimate quantitative and qualitative changes in the regulation of the cardiovascular system. The combination of the Stroop test and the monitoring of the cardiovascular system make it possible to assess not only attention and cognitive function parameters, but the phases of the stress response of regulatory systems as well. The purpose of the study was to analyze the relationship between stress factor and the functional state of adolescent cardiovascular system. In the context of stress factor (Stroop test), the circulatory system of students gets activated, and its indicators vary differently among boys and girls. At rest, girls have the lowest performance of the circulatory system. Before the test, heart rates vary in boys and girls in different ways. In the course of our study, we have found out a direct relationship between heart rate, blood pressure before and after psycho-emotional load that testifies the predominance of the sympathoadrenal system activity. We have revealed the arterial hypertension is determined by physiological and social factors. Prevention of arterial hypertension in existing standards of schools requires reconsidering and improving of educational approaches, especially in terms of physical education.


Author(s):  
I. Masliak ◽  
Y. Berlova

The article provides the results of determining the state of the cardiorespiratory system and the level of physical fitness of the 1st year students of The Housing and Communal College. As a result of the conducted research, “below the average” level of functioning the cardiorespiratory system was defined at students. So, measures of the functional state of the respiratory system (Skibinski index) when compared with the assessment scale are equal to the score - 2 points, which corresponds to “below the average” level. Measures of the state of the cardiovascular system regulation (Robinson index) when compared with the scoring scale at students of both study groups are equal to the score - 3 points, which corresponds to the “average” level. The state of the cardiorespiratory system of boys is mainly higher than girls’ one in the sexual aspect. The exception is the results of measuring systolic blood pressure, where there is an opposite trend - the indicators of girls are higher than the results of boys. At the same time, the noted differences are valid only in indicators of the state of the respiratory system (p<0,05; 0,001). The distinctions are unreliable (p>0,05) in indicators of the cardiovascular system. The data of the conducted research indicates the “average” level of physical fitness at boys, which on average equals the “good” and “sufficient” levels at girls, which on average equals the score “satisfactory”. So, the boys have indicators for the development of all physical qualities that meet the assessment “good”. Speed, high-speed and power qualities and endurance meet the assessment “satisfactory”, strength and agility - the assessment “good” at girls. The physical fitness of boys is significantly higher than girls’ one in the sexual aspect (p< 0,001). The exception is the development of flexibility, where the results of girls are higher than boys’ ones, but unreliably (p>0,05). Thus, the results of the research indicate the feasibility of introducing the special physical exercises aimed at improving the functional state of the cardiorespiratory system and developing basic physical qualities into the physical education process of the 1st year students of institutions of higher education of the I-II level of accreditation.


Author(s):  
Ljiljana Sulovic ◽  
Vladimir Sulovic ◽  
Zorica Zivkovic ◽  
Maja Vasic ◽  
Nenad Sulovic ◽  
...  

Assessment of cardiac function is the leading parameter when evaluating the state of the cardiovascular system of patients undergoing chronic hemodialysis. The aim of the paper: to assess the state of the cardiovascular system of these patients using new sensitive echocardiography and Doppler techniques and thus advance the prevention of cardiovascular disease.Method: Twenty children with end-stage renal insufficiency on chronic hemodialysis and twenty healthy controls underwent echocardiographic monitoring using standard Doppler and tissue Doppler imaging. Structural and functional changes in the left ventricle were evaluated.Results: Patients on hemodialysis had significantly greater left ventricular mass indices compared to the controls (p&lt;0.001). The patients on hemodialysis had preserved systolic function &ndash; their fractional shortening, ejection fraction and Sm (systolic myocardial velocity) did not differ significantly compared to the controls (p&gt;0.05). Early diastolic function in children on hemodialysis was also preserved: the E/A and Em/Am ratio did not differ significantly from the control group (p&gt;0.05). Children on hemodialysis exhibited impaired late diastolic function (compliance index), that is, considerably higher E/Em compared to controls (p&lt;0.00). Myocardial Performance Index values showed statistically significant elevation in children on hemodialysis compared to the control group (p&lt;0.001).Conclusion: Tissue Doppler in tandem with conventional Pulsed Doppler can provide additional information on left ventricular filling pressures (E/Em) in children on hemodialysis. It is therefore recommended to perform routine measuring of Em waves and the E/Em ratio, not only in order to evaluate myocardial relaxation and ventricular filling pressures, but primarily to stratify risk and provide a prognosis.


2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Yihua Xu ◽  
Li Wang ◽  
Siyuan Cao ◽  
Ruihua Hu ◽  
Rui Liu ◽  
...  

Abstract Background Circadian rhythm disruption impacts a wide range of physiological processes, including fertility. However, the effect of circadian disruption on male spermatogenesis and fertility, and treatments for these effects have been largely unexplored at the molecular level. Methods In this study, we examined the effects of genipin on improving the reproductive health problems caused by circadian disruption. Three groups of animals were fed under different conditions: control group (normal T cycle with saline), group of shortened T cycles (Light/Dark = 4 hours/4 hours) with saline, and a group of shortened T cycles with genipin by oral gavage. The male fertility was evaluated by fertility study and pups parameters analysis after successful sexual behavior and mating with female mice. We sacrificed the treated animals after 5 or 10 weeks and collected the testis, sperm and serum for histological analysis, sperm motility assay, and serum hormone detection, respectively. Furthermore, the effect of genipin was assessed by detection of progesterone secretion and steroidogenic key proteins expression, including StAR and CYP11A1, in mouse Leydig tumor MLTC-1 cells. Results Male mice exposed to shortened light-dark cycles, much shorter than 24 hours, had reduced fertility with decreased sperm concentrations and sperm motility. Male mice under circadian disruption have reduced testis size and abnormal morphology, leading to lower fertility rates, reduced litter size and pup body weight. Treatment with exogenous genipin, a natural plant-derived compound, alleviated circadian disruption-induced damage to fertility and spermatogenesis and normalized testosterone, dihydrotestosterone (DHT), and androstenedione (ASD) levels in the male mice. The levels of key proteins involved in steroidogenesis, StAR and CYP11A1, were reduced in mouse testes after the circadian disruption, but genipin treatment restored the reduction. The mRNA expression of SRD5A1, which encodes an androgen synthesis enzyme, was also upregulated by genipin treatment. Furthermore, genipin treatment showed a positive effect on steroidogenesis in MLTC-1 cells, resulting in an increase in hormone secretion and the upregulation of StAR and CYP11A1. Conclusions Our results showed an association between circadian disruption and reproductive health problems in male mice and indicated that treatments with genipin have positive effects on the reproductive health of male mice with circadian rhythm disorders.


Author(s):  
Ljiljana Sulovic ◽  
Vladimir Sulovic ◽  
Zorica Zivkovic ◽  
Jovan Zivkovic ◽  
Maja Vasic ◽  
...  

Assessment of cardiac function is the leading parameter when evaluating the state of the cardiovascular system of patients undergoing chronic hemodialysis. The aim of the paper: to assess the state of the cardiovascular system of these patients using new sensitive echocardiography and Doppler techniques and thus advance the prevention of cardiovascular disease. Method: Twenty children with end-stage renal insufficiency on chronic hemodialysis and twenty healthy controls underwent echocardiographic monitoring using standard Doppler &nbsp;and tissue Doppler imaging. Structural and functional changes in the left ventricle were evaluated. Results: Patients on hemodialysis had significantly greater left ventricular mass indices compared to the controls (p &lt; 0.001). The patients on hemodialysis had preserved systolic function&mdash;their fractional shortening, ejection fraction and Sm (systolic myocardial velocity) did not differ significantly compared to the controls (p &gt; 0.05). Early diastolic function in children on hemodialysis was also preserved: the E/A and Em/Am ratio did not differ significantly from the control group (p &gt; 0.05). Children on hemodialysis exhibited impaired late diastolic function (compliance index), that is, considerably higher E/Em compared to controls (p &lt; 0.00). Myocardial Performance Index values showed statistically significant elevation in children on hemodialysis compared to the control group (p &lt; 0.001). Conclusion: Tissue Doppler in tandem with conventional Pulsed Doppler can provide additional information on left ventricular filling pressures (E/Em) in children on hemodialysis. It is therefore recommended to perform routine measuring of Em waves and the E/Em ratio, not only in order to evaluate myocardial relaxation and ventricular filling pressures, but primarily to stratify risk and provide a prognosis.


Author(s):  
M M Matlubov ◽  
A A Semenixin ◽  
S A Ruzibaev ◽  
N I Zakirova ◽  
O V Kim

In order to study the state of hemodynamics in pregnant women with obesity of varying severity were examined 84 pregnant women aged between 23 and 28 years at 36-38 weeks gestation. The control group included 21 pregnant women of similar age and gestational age with normal body weight. All observed patients, pregnancy according obstetrical consultation was recognized uncomplicated. The degree of obesity was assessed by body mass index. Researches conducted showed that overweight as its progression has a very adverse effect on hemodynamics and functional state of the cardiovascular system as a whole, reduces coronary reserve. The most pronounced violation of the functional state of the cardiovascular system occur in obesity 2nd and 3rd degree.


2021 ◽  
Vol 23 (6) ◽  
pp. 806-812
Author(s):  
E. O. Asanov ◽  
Yu. I. Holubova ◽  
I. A. Dyba ◽  
S. O. Asanova

The aim of the work is to find out the effectiveness and duration of the breathing exercises with PEEP action on the cardiovascular system state in older patients with COPD. Materials and methods. A total of 35 patients with COPD aged 60–74 years were examined. All the patients were divided into two groups: the main group (18 people) who received breathing exercises with PEEP, and the control group (17 people) who received simulated exercises. The cardiovascular system state was assessed. The examinations were performed in the initial state (before training), immediately after, one month later, and three months after the training course. Results. The cardiovascular system state improved as a result of breathing exercises with PEEP in older patients with COPD. At the same time, the duration of the breathing exercises with PEEP action was short; the effect of their use was not preserved in a month. Relationships between shifts in SpO2 and cardiac output, as well as between shifts in SpO2 and peripheral vascular resistance immediately after the use of breathing exercises with PEEP in older patients with COPD have been established. A more significant and prolonged effect of breathing exercises with PEEP on the cardiovascular system functional state was observed in older COPD patients with more severe symptoms of the disease. Conclusions. The increase in cardiovascular performance was influenced by breathing exercises with PEEP in older COPD patients due to the improved lung oxygenation capacity. The effect of breathing exercises with PEEP remained within a month after the training course and was more stable and longer in patients with severe clinical symptoms. Older COPD patients are advised to repeat the courses of breathing exercises with PEEP every month.


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