scholarly journals The influence of different feed additives to performances and immune response in broiler chicken

2007 ◽  
Vol 57 (2-3) ◽  
pp. 217-229 ◽  
Author(s):  
Tokic Vesna ◽  
Lazarevic Miodrag ◽  
Sinovec Z. ◽  
Tokic A.
Keyword(s):  
Immune Response ◽  
Broiler Chicken ◽  
Feed Additives

scholarly journals Antibiotics as a Feed Additive Promote Growth of Chickens by Modulating the Gut Microbiome

2021 ◽  
Author(s):  
Xiangkai Li ◽  
Ying Wu ◽  
Liang Peng ◽  
Rong Han ◽  
pengya Feng ◽  
...  
Keyword(s):  
Immune Response ◽  
Amino Acid ◽  
Gut Microbiome ◽  
Broiler Chicken ◽  
Intestinal Flora ◽  
Feed Additives ◽  
Secretory Iga ◽  
Feed Additive ◽  
Control Group ◽  
Average Weight

Abstract Background: Antibiotics widely used as growth promoters in the agricultural industry, but their mechanisms have not been fully explored. Antibiotics has a connection effect on the gut microbiome which plays a vital role in host metabolism and immune response. Here, we investigated the association of antibiotic and gut microbiome in broiler chicken.Methods: Polymyxin (PMX) and amoxicillin (AMX) were selected as feed additives in broiler chicken, and gut bacterial composition assessed by quantitative real-time PCR and high-throughput sequencing of bacterial 16S rRNA. Metabolome and lipidomic of feces and serum samples were analyzed using liquid chromatograpy-tandem mass spectrometry (LC-MS). We further assessed changes in the microbiota and metabolism which underwent antibiotics treatment.Results: The administration of antibiotic increasing, the average weight of chickens by up to 4.9% and altered number and structure of the intestinal microflora compared to the un-treated group. The bacterial component of gut microbiota in antibiotic groups was showed a lower prevalence of Firmicutes and Bacteroidetes phyla and higher prevalence of a high diversity (Proteobacteria). In metabolome of feces and serum, amino acid such as phenylalanine, valine, methionine and aspartic acid, and lipid metabolic (Lysolecithin, Oxalosuccinic acid and phosphatidylcholine) were all higher among obese chicks in antibiotics groups. Serum IgG (18.2%–32.7%) and intestinal secretory IgA (27.5%–28.6%) were decreased compared with control group, and immune associated metabolome in serum lipidomic were also fluctuated with the concentration of AMX and PMX. Conclusions: The data suggested that the structure and quantity of intestinal flora has to affect amino acid and lipid metabolic homeostasis, and immune response, which can serve as a target in the prevention and treatment of metabolic disorders.

scholarly journals Correction to: Are the energy matrix values of the different feed additives in broiler chicken diets could be summed?

2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Abdallah E. Metwally ◽  
Ahmed A. A. Abdel-Wareth ◽  
Ahmed A. Saleh ◽  
Shimaa A. Amer
Keyword(s):  
Broiler Chicken ◽  
Feed Additives ◽  
Energy Matrix

An amendment to this paper has been published and can be accessed via the original article.

Effect of dietary inclusion of turmeric (Curcuma longa) and garlic (Allium sativum) powders as feed additives on performance of broiler chicken

2021 ◽  
Vol 38 (1) ◽  
pp. 92-99
Author(s):  
Sonali Chowdhary ◽  
Nazam Khan ◽  
R.K. Sharma ◽  
Jasvinder Singh Sasan ◽  
Vikas Mahajan
Keyword(s):  
Broiler Chicken ◽  
Allium Sativum ◽  
Curcuma Longa ◽  
Feed Additives

scholarly journals Effect of colistin and tylosin used as feed additives on the performance, diarrhea incidence, and immune response of nursery pigs

2016 ◽  
Vol 37 (4) ◽  
pp. 1947 ◽  
Author(s):  
Kelly Mazutti ◽  
Leandro Batista Costa ◽  
Lígia Valéria Nascimento ◽  
Tobias Fernandes Filho ◽  
Breno Castello Branco Beirão ◽  
...  
Keyword(s):  
Immune Response ◽  
Feed Intake ◽  
Immune Cell ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Feed Additives ◽  
Control Group ◽  
Feed Conversion ◽  
Nursery Pigs ◽  
Diarrhea Incidence

For the last several decades, antimicrobial compounds have been used as feed additives to promote piglet growth at weaning, through the prevention of subclinical and clinical disease. However, few studies have assessed the influence of these antibiotics on the immune response of nursery pigs, as well as the relation between performance, health, and immunity of animals that receive feed additives. Therefore, the present study aimed to evaluate the effects of colistin and tylosin when used as feed additives on the performance, incidence of diarrhea, and immune response of nursery pigs. In this study, 72 weaned pigs (average age, 28 days) were allotted into one of three treatment groups: a control group (feed with no antibiotics), tylosin group (feed containing 22 ppm tylosin), and colistin group (feed containing 20 ppm colistin). Weekly, during a five week period, the average daily feed intake, average daily gain, and feed conversion ratio of the pigs were evaluated. Stools were scored daily, in accordance with a fecal texture scale. Blood samples were collected on the day of housing (d0) and on d7, d21, d28, and d35 for immune cell phenotyping. The results of this study showed that piglets in both the colistin and tylosin groups exhibited a significantly higher average daily feed intake, resulting in a higher body weight at the end of the experimental period (d35) when compared with piglets from the control group. Colistin and tylosin also significantly reduced the incidence of diarrhea. Colistin and tylosin modulated the piglets’ immune responses, particularly on d28, by changing the percentage of circulating B lymphocytes, CD4+CD8+ T cells, and the CD4:CD8 ratio.

scholarly journals Review: Peluang Pengembangan Imbuhan Pakan Fitogenik Sebagai Pengganti Antibiotika dalam Ransum Ayam Pedaging di Indonesia

2019 ◽  
Vol 6 (2) ◽  
pp. 188
Author(s):  
Cecep Hidayat ◽  
Rahman Rahman
Keyword(s):  
Broiler Chicken ◽  
Scientific Literature ◽  
Feed Additives ◽  
Feed Additive ◽  
Growth Promoter ◽  
Literature Study ◽  
The Third ◽  
Feed Industry ◽  
Broiler Diet ◽  
Main Support

ABSTRAK                                                            Seiring dengan telah dilarangnya penggunaan antibiotic growth promotor (AGP) dalam pakan oleh pemerintah Indonesia, maka pencarian pengganti AGP mejadi penting saat ini. Imbuhan pakan fitogenik menjadi salah satu pengganti AGP potensial. Makalah ini ditulis untuk mengungkap peluang pengembangan imbuhan pakan fitogenik sebagai pengganti AGP dalam ransum ayam pedaging di Indonesia. Metode penulisan makalah dilakukan dengan beberapa tahapan. Tahapan pertama, tahap persiapan, dilakukan dengan mengumpulkan dan membaca jurnal, makalah prosiding, buku yang diperoleh dari hasil dari pencarian  pada internet. Dilanjutkan dengan memilih dan menentukan jurnal hasil penelitian, makalah ilmiah pada prosiding, buku terkait dengan topik yang sudah ditentukan. Tahapan ke dua, penyusunan outline makalah yang akan ditulis, dimana pada tahapan ini untuk menentukan skema berfikir penulis terkait dengan topik yang akan di bahas. Tahapan ke tiga, mengembangkan kerangka makalah dengan menggunakan literatur ilmiah, teori, hasil penelitian yang sudah diperoleh. Tahapan ke empat, pemeriksaan terhadap isi makalah yang sudah ditulis, baik secara substansi maupun redaksional. Berdasarkan studi pustaka yang dilakukan disimpulkan bahwa imbuhan pakan fitogenik dari berbagai jenis tanaman potensial digunakan sebagai pengganti AGP dalam pakan ayam pedaging. Kebutuhan akan daging ayam nasional yang semakin tinggi setiap tahunnya, menjadi peluang betapa besarnya pasar akan kebutuhan pengganti AGP di Indonesia. Sinergisme antara lembaga penelitian-perguruan tinggi dengan pelaku industri pakan dan imbuhan pakan menjadi penopang utama dalam pengembangan imbuhan pakan fitogenik di Indonesia.Kata Kunci: imbuhan pakan fitogenik, ayam pedagingABSTRACTKeywords: pytogenic feed additive, broiler chicken The use of antibiotic growth promoter (AGP) in feed has been banned by the Indonesian government. Therefore, the search for alternative AGP continues to be carried out. The addition of phytogenic is one of the potential alternatives because it has the same ability as AGP. This paper was written to reveal the opportunities for developing phytogenic feed additives as a substitute for antibiotics in broiler diet in Indonesia. The method of writing this paper was done in several stages. The first stage, the preparation, is done by searching and reading journals, proceedings, books obtained from the internet. The second method is the preparation of the outline of the paper to be written, to determine the author's thinking scheme related to the topic to be discussed. The third method is developing a framework of thought by using scientific literature obtained and read before. Fourth method is examination of the contents of papers that have been written, both substantially and editorially. Based on the literature study, it was concluded that the phytogenic feed additives from various types of plants should be considered as a substitute for AGP in broiler diet.  The need for national chicken meat which is getting higher every year becomes an opportunity for how big the market will be for AGP's replacement in Indonesia. Synergism between university-research institutions and feed industry is the main support in developing phytogenic feed additives in Indonesia.Keywords: pytogenic feed additive, broiler chicken

scholarly journals 398 Towards new feeding approaches for optimizing nutritional status, immunity and host-microbiota interactions in neonatal and weaned piglets

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 181-181
Author(s):  
Martin Lessard ◽  
Mylène Blais ◽  
Guylaine Talbot ◽  
J Jacques Matte ◽  
Ann Letellier ◽  
...  
Keyword(s):  
Immune Response ◽  
Immune System ◽  
Intestinal Microbiota ◽  
System Development ◽  
Feed Additives ◽  
Epithelial Cell Line ◽  
Host Immune System ◽  
Gut Health ◽  
Weaned Piglets ◽  
Immune System Development

Abstract Lactation, feeding conditions, microbial interventions and piglet growth in the first few weeks of life have important impact on the intestinal microbiota establishment and immune system development of piglets. Indeed, colostrum and milk contain various bioactive components such as immune factors, antimicrobial peptides and oligosaccharides that contribute to maintain intestinal homeostasis and regulate interactions between microbiota and host immune system. Recent results revealed that low birth weight piglet (LBWP) with poor weight gain during the first two weeks of life develop different intestinal microbiota and immune response profiles compared to high BWP (HBWP) littermates. Consequently, piglets within litters may have different resilience to infections after weaning and benefit from feed additives in a specific manner. A study has been performed to evaluate the potential of bovine colostrum extract (BC) as replacement to plasma proteins for improving gut health and resilience to Salmonella infection in piglets. Results revealed that in weaned piglets fed BC, intestinal microbiota was differently modulated and bacterial dysbiosis induced by Salmonella was restored faster. Moreover, expression of genes involved in innate immunity such as β-defensin-2 and glutathione peroxidase-2 was respectively down- and up-regulated in BC fed piglets. A combination of dietary supplementation with BC, cupper and vitamins A and D has also been tested in LBWP and HBWP, and there is clear evidence that BC in combination with other feed additives promote growth and gut health in both LBWP and HBWP. The porcine intestinal epithelial cell line IPEC-J2 was used to better understand the functional properties of BC. Results indicated that BC improves wound healing, enhances barrier function and modulates the expression of several genes involved in innate immune response. Finally, as microbial intervention, the potential of fecal transplantation to modulate intestinal microbiota and immune system development of piglets is under investigation and will be discussed.

scholarly journals Effects of 5-Aminolevulinic Acid as a Supplement on Animal Performance, Iron Status, and Immune Response in Farm Animals: A Review

Animals ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1352
Author(s):  
Amin Omar Hendawy ◽  
Mostafa Sayed Khattab ◽  
Satoshi Sugimura ◽  
Kan Sato
Keyword(s):  
Immune Response ◽  
Egg Production ◽  
Aminolevulinic Acid ◽  
Iron Status ◽  
White Blood Cells ◽  
Feed Additives ◽  
Farm Animals ◽  
Clear Understanding ◽  
Standard Procedures ◽  
Cell Mediated Immune Response

Efforts directed toward enhancing animals’ productivity are focused on evaluating the effects of non-traditional feed additives that are safer than antibiotics, which have been banned because of their health hazards. Many studies used an amino acid that contributes to heme biosynthesis, known as 5-aminolevulinic acid (5-ALA), to promote the productivity of farm animals. However, these studies demonstrate inconsistent results. In order to develop a clear understanding of the effects of 5-ALA in farm animals, we comprehensively searched PubMed and Web of Science for studies evaluating 5-ALA effects on the performance, iron status, and immune response of different farm animals. The search retrieved 1369 publications, out of which 16 trials were relevant. The 5-ALA-relevant data and methodological attributes of these trials were extracted/evaluated by two independent researchers, based on a set of defined criteria. Samples were comprised of pigs, chickens, and dairy cows. The 5-ALA doses ranged from 2 mg to 1 g/kg of feed, and treatment duration ranged from 10 to 142 days. Overall, 5-ALA improved iron status in most studies and increased white blood cells count in 3 out of 10 studies, in addition to improving animals’ cell-mediated immune response following immune stimulation with lipopolysaccharide. Inconsistent findings were reported for growth performance and egg production; however, a combination of 10 mg/kg of 5-ALA with 500 mg/kg of vitamin C promoted the highest egg production. In addition, 5-ALA improved milk protein concentration. In conclusion, 5-ALA can enhance farm animals’ iron status and immune response; however, the heterogeneity of the reviewed studies limits the generalizability of the findings. Standard procedures and outcome measures are needed to confirm the benefits of 5-ALA. Attention should also be paid to any adverse effects.

scholarly journals Influence of Feeding Quinoa (Chenopodium quinoa) Seeds and Prickly Pear Fruit (Opuntia ficus indica) Peel on the Immune Response and Resistance to Aeromonas sobria Infection in Nile Tilapia (Oreochromis niloticus)

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2266
Author(s):  
Shaimaa A. A. Ahmed ◽  
Ghada I. Abd El-Rahman ◽  
Amany Behairy ◽  
Rasha R. Beheiry ◽  
Basma M. Hendam ◽  
...  
Keyword(s):  
Immune Response ◽  
Oreochromis Niloticus ◽  
Nile Tilapia ◽  
Relative Survival ◽  
Feed Additives ◽  
Prickly Pear ◽  
Pear Fruit ◽  
Fruit Peel ◽  
Aeromonas Sobria ◽  
Nile Tilapia Oreochromis Niloticus

In recent times, nutraceuticals have been used extensively to identify promising feed additives for the improvement of the aquaculture industry through the enhancement of growth and survival rates, potentiation of the immune responses, and fortification of the resistance against infectious bacterial diseases. In this study, Nile tilapia (Oreochromis niloticus) were fed with diets supplemented with quinoa seeds (QU) or prickly pear fruit peel (PP) at the dose levels of 10% or 20% of the diet. After 45 days of the feeding trial, the fish were exposed to Aeromonas sobria (A. sobria) challenge. The pre-challenge indices indicated that both supplements mediated a significant improvement in most of the estimated parameters, including survival rate, antioxidant status, hematological and immunological indices, and hepatoprotective potential. These effects were recorded in the groups fed with high doses of the supplements (20%). The least changes were observed in the QU10-supplemented fish. In the spleen tissue, the TGF-β gene was upregulated in the PP10-, PP20- and QU20-supplemented groups, while the expression of the IFN-γ gene remained unaffected in all the supplemented groups, except for the PP20-supplemented group, which showed an upregulation. After the challenge with A. sobria, the relative survival percentage was improved by the supplementation of PP and QU, particularly in the PP20-supplemented group, possibly via the promotion of immunological responses, hepatoprotective potency, and modulation of the studied genes. Moreover, the morphological structure of the tissues showed marked recovery. The findings suggest that Nile tilapia fed with different levels of PP peel and QU seeds, particularly at the level of 20%, enhanced the immune response in fish and improved their resistance against A. sobria infection.

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