PENURUNAN LAJU PENUAAN REPRODUKSI MENCIT JANTAN (Mus muculus.Linn) DENGAN PEMBERIAN EKSTRAK JAHE (Zingiber officinale) DALAM PAKAN

2018 ◽  
Vol 5 (1) ◽  
pp. 1-10
Author(s):  
Sutyarso Sutyarso ◽  
Sumayyah Annida ◽  
M. Kanedi ◽  
Hendri Busman ◽  
Nuning Nurcahyani
Keyword(s):  
Mus Musculus ◽  
Reproductive Function ◽  
Zingiber Officinale ◽  
Male Mice ◽  
Ginger Extract ◽  
Normal Morphology ◽  
Aging Period ◽  
Ginger Rhizome ◽  
Rate Of Decline

The ginger rhizome contains antioxidants and is chemoprotective, therefore we suspect it can decrease the aging rate in the reproductive system. The purpose of this study, to determine the effect of ginger extract (Zingiber officinale) against reproductive aging of male mice (Mus musculus). This study, using 36 male mice (Mus musculus) aged 12-14 months, divided into three groups each 12 tails. Group 1 as controls, groups 2 and 3 were given 50 mg and 100 mg ginger extract / kg of pellets. The pellet is given for 70 days ad libitum. Next, observed the number of spermatogenic cells, as well as the number and quality of spermatozoa. The results showed that ginger extract had an effect on spermatogenic and spermatozoa (P <0,01) cells of mice. The results of preleptotene spermatocyte, pakhiten and spermatid spermatocyte counts were higher, as were the number of spermatozoa, the percentage of viability and motility, and the normal morphology of spermatozoa were more in the group given ginger extract than control (P <0.01). It was concluded that ginger rhizome extract given to mice entering the aging period could inhibit the rate of decline in reproductive function.

scholarly journals PERBEDAAN KUALITAS SPERMATOZOA MENCIT JANTAN (MUS MUSCULUS L) YANG DIBERIKAN VITAMIN C SETELAH PEMAPARAN ASAP ROKOK

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Vergina Claudia ◽  
Edwin De Queljoe ◽  
Lydia Tendean
Keyword(s):  
Treatment Group ◽  
Vitamin C ◽  
Cigarette Smoke ◽  
Mus Musculus ◽  
Sperm Concentration ◽  
Control Group ◽  
Male Mice ◽  
Normal Morphology ◽  
The Mean

Abstract: Vitamin C is an antioxidant that suppresses the oxidative stress caused by cigarette smoke purpose of this study demonstrate whether vitamin C can provide a different quality of sperm male mice Mus musculus L are given exposure to cigarette smoke. Methodology: The study subjects are 32 male mice Mus musculus L, which were randomly divided into 2 groups. The first group was the control group (K) who received treatment exposure from cigarette smoke without giving vitamin C and the second group is the treatment group (P) are given exposure from cigarette smoke and vitamin C dose of 0.40 mg / gBB /day. The treatment during 30 days, on day 31 the mice were terminated, and then examined the quality of spermatozoa motility of spermatozoa, sperm concentration and morphology of spermatozoa. Results: Test oneway ANOVA on the mean motility of spermatozoa showed Ma control group (47,38%), Mb (11,88%), Mc (18,13%), Md (22,63%) and the Ma treatment group (11.68%), Mb (17,04%), Mc (35,77%), Md (16,5%). The mean concentration of spermatozoa obtained 63,34x105/ml control group and the treatment group and the mean morphology of spermatozoa 81,75x105/ml control group showed normal morphology 50% and abnormal morphology 56,189% while the treatment group showed normal morphology 60% and 40% abnormal. Result from Oneway ANOVA test there are differences significant in the morphology of spermatozoa, concentration of spermatozoa, sperm concentration, and sperm morphology between groups (p <0,05). Conclusion: Vitamin C can improve the quality of spermatozoa after exposure to cigarette smoke. Keywords: ciggaratte, vitamin C, quality of spermatozoa.   Abstrak: Vitamin C merupakan  antioksidan yang menekan proses stres oksidatif akibat asap rokok Tujuan penelitian membuktikan apakah vitamin C dapat memberikan perbedaan kualitas spermatozoa mencit jantan Mus Musculus L yang diberi paparan asap rokok. Metodologi: Subyek penelitian 32 ekor mencit jantan Mus Musculus L, yang dibagi secara acak menjadi 2 kelompok. Kelompok pertama adalah kelompok kontrol (K) yang mendapat perlakuan paparan asap rokok tanpa pemberian vitamin C dan kelompok kedua yaitu kelompok perlakuan (P) yang diberi paparan asap rokok dan vitamin C dosis 0,40mg/gBB/hari. Perlakuan berlangsung selama 30 hari, pada hari ke-31 mencit tersebut diterminasi, kemudian dilakukan pemeriksaan kualitas spermatozoa yaitu motilitas spermatozoa, konsentrasi spermatozoa dan morfologi spermatozoa. Hasil: Uji oneway ANOVA pada rerata motilitas spermatozoa kelompok kontrol menunjukan Ma(47.38%), Mb(11.88%), Mc(18.13%), Md(22.63%) dan kelompok perlakuan Ma(11.68%), Mb(17.04%), Mc(35.77%), Md(16.5%). Rerata konsentrasi spermatozoa kelompok kontrol didapatkan 63.34x105/ml, dan kelompok perlakuan 81.75x105/ml dan rerata morfologi spermatozoa kelompok kontrol menunjukkan morfologi normal 50% dan morfologi abnormal 56,189% sedangkan kelompok perlakuan menunjukkan morfologi normal 60% dan abnormal 40%. Hasil Uji oneway ANOVA terdapat perbedaan yang signifikan pada konsentrasi spermatozoa yaitu morfologi spermatozoa, konsentrasi spermatozoa, dan morfologi spermatozoa antar kelompok (p<0.05). Kesimpulan: Pemberian vitamin C dapat memperbaiki kualitas spermatozoa setelah pemaparan asap rokok. Kata kunci: Rokok, vitamin C, kualitas spermatozoa.

EFEK PENAMBAHAN EKSTRAK AIR JAHE (Zingiber officinale Roscoe) DAN PENYIMPANAN DINGIN TERHADAP MUTU SENSORI IKAN TUNA (Thunnus albacores)

2010 ◽  
Vol 6 (1) ◽  
pp. 36
Author(s):  
Silvana Dinaintang Harikedua
Keyword(s):  
Sensory Quality ◽  
Zingiber Officinale ◽  
The Other ◽  
Ginger Extract ◽  
Other Hand ◽  
Storage Treatment ◽  
Zingiber Officinale Roscoe ◽  
Hedonic Scale ◽  
And Storage

The objective of this study was to investigate the effect of ginger extract addition and refrigerate storage on sensory quality of Tuna through panelist’s perception. Panelists (n=30) evaluated samples for overall appearance and flavor attribute using hedonic scale 1–7. The sample which is more acceptable by panelists on flavor attributes having 3% gingers extract and storage for 3 days. The less acceptable sample on flavor attribute having 0% ginger extract and storage for 9 days. On the other hand, the sample which is more acceptable by panelists on overall appearance having 0% ginger extract without storage treatment. The less acceptable sample on overall appearance having 3% ginger extract and storage for 9 days.

scholarly journals Aggressiveness and Libido of Male Mus musculus L. in Ethanol Extract of Red Ginger (Zingiber officinale Roxb. var. Rubrum)

2019 ◽  
Vol 6 (1) ◽  
pp. 8-14
Author(s):  
Nida Nurhanifah ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Free Radicals ◽  
Ethanol Extract ◽  
Serum Testosterone ◽  
Zingiber Officinale ◽  
The Body ◽  
Male Mice ◽  
Ginger Extract ◽  
Treatment Groups ◽  
Randomized Design ◽  
Red Ginger

The residue of paraquat herbicides may cause human health problems. Paraquat causes the testosterone hormone to decline. Testosterone hormone affects aggressive and sexual behavior. It is caused by free radicals in the body. Free radicals can be non-reactive if in the body there are antioxidants. Red ginger could be used as an antioxidant because it has active phenolic compounds, such as arginine, gingerol, shogaol, zingerone, gingerdiol, and zingiber. Ginger could increase serum testosterone levels. The purpose of this research is to know the effect of red ginger ethanol extract on aggressiveness and libido of male mice induced by paraquat herbicide. This study used a Completely Randomized Design (RAL) consisting of six treatment groups with four replications each. Group P1 as control (aqua dest), P2 (paraquat at dose 20 mg/kg BM), P3, P4, P5 (paraquat with dose 20 mg/kg BM and red ginger extract at 200 mg/kg BM, 400 mg/kg BM, 600 mg/kg BM) and P6 (red ginger extract at 600mg/kg BM). Paraquat is given 2 times a week for 21 days and the red ginger extract is given daily for 35 days. The result of analysis with One-way ANOVA and continued BNT at 5% showed that giving of red ginger ethanol extract can increase aggressive behavior and libido of male mice induced paraquat herbicide.

scholarly journals PENGARUH PEMBERIAN EKSTRAK ETANOL JAHE MERAH (Zingiber Officinale Roxb var Rubrum) TERHADAP KUANTITAS DAN KUALITAS SPERMATOZOA MENCIT JANTAN (Mus musculus L.) YANG DIINDUKSI PARAQUAT DIKLORIDA

2019 ◽  
Vol 5 (2) ◽  
pp. 47-54
Author(s):  
Dian Anggraini ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Body Weight ◽  
Mus Musculus ◽  
Sperm Count ◽  
Zingiber Officinale ◽  
The Body ◽  
Test Material ◽  
Control Group ◽  
Ginger Extract ◽  
Wide Range ◽  
Red Ginger

Paraquat is one of the chemicals that contributes to increasing pollution Indonesia. The careless use of paraquat can increase production of ROS (Reactive Oxygen Species), resulting in damage to a wide range of vital organs and reproductive system disorders such as infertility. ROS in the body can be captured by antioxidants. Red Ginger contains high antioxidants because there are active phenolic compounds such as gingerol, shagaol, zingeron, ginggerdiol, and zingibren which are proven to protect body cells from damage caused by ROS. This study was aimed to test the effectiveness of red ginger extract (Zingiber officinale Roxb. Var. Rubrum) on the quantity and quality of sperm in male mice (Mus musculus L.) induced by paraquat dichloride.This research uses a completely randomized design and is divided into six treatment groups with each four replications: K1 as the control group (only given H2O); K2 (paraquat induced a dose of 20 mg/kg Body Weight (BW) without the administration of the test substances); K3; K4; K5 (paraquat induced a dose of 20 mg/kg Body Weight (BW) and was given a red ginger extract at a dose of consecutive succession 6 mg / ml, 12 mg / ml, 18 mg / ml) and K6 (Only given a test material the red ginger extract as much as 18 mg / ml). Paraquat was given 2 times a week for 21 days and the red ginger extract was given for 35 days. The results of analysis by One-way ANOVA followed LSD at 5% significance level showed the ethanolic extract of red ginger can increase the sperm count, motility, viability and Morphology sperm of mice induced by the paraquat diklorida.

scholarly journals EFFECT OF RED GINGER EXTRACT (Zingiber officinale Var Rubrum) ON CHEMICAL AND ORGANOLEPTICS QUALITY OF AMBON CURUP BANANA WET “SALE”

2019 ◽  
Vol 9 (1) ◽  
pp. 28-36
Author(s):  
Wuri Marsigit ◽  
Laili Susanti ◽  
Lia Marzalena
Keyword(s):  
Immersion Time ◽  
Consumer Preference ◽  
Zingiber Officinale ◽  
Ash Content ◽  
Chemical Quality ◽  
Ginger Extract ◽  
Average Value ◽  
Randomized Design ◽  
Red Ginger

ABSTRACTQuality improvement  of sale banana ambon curup was necessary to increase chemical and organoleptics quality and consumer preference. The  purpose  of  this  study  was  to  determine  the  effect  of  variations  in  theconcentration   of   red   ginger   juice   and   the   length   of   immersion   on  chemical   quality, microbiology and organoleptic wet sale of banana ambon curup. By using (RAL) 2 factorial randomized design, the concentration of red ginger juice was 5%, 10% and 15% with a time of immersion for 20 and 10 minutes. The analytical method used was ANOVA. The results of the study found that sucrose levels were 37.56% to 57.54 %, the water content was 36.66% and 38.33%, ash content was 1.47 % to 1.87 %.  The  panelists  preferred  the  average  value  of  the  whole (texture, aroma, and tate)  was  found  in  the  P1T1 sample  with  a  treatment  of  red  ginger  concentration  of  0.05%  and  immersion  time  for  10 minut  

scholarly journals Organ-Protective Effect of Red Ginger Extracts in Male Mice Induced by Paraquat

2019 ◽  
Vol 6 (2) ◽  
pp. 8-17
Author(s):  
Kamiliah Tsany ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Ethanol Extract ◽  
Zingiber Officinale ◽  
The Body ◽  
Control Group ◽  
Male Mice ◽  
Ginger Extract ◽  
Randomized Design ◽  
Significant Difference ◽  
Lung Histology ◽  
Red Ginger

Paraquat is a toxic compound that disrupts biochemical processes in the body, cell death, and multi-organ failure. The liver and lung are the target organ of paraquat toxicity. The body needs antioxidants to counteract free radicals. Red ginger (Zingiber officinale Roxb. Var rubrum) is a spice that contains antioxidants. This study was conducted to determine the effect of ethanol extract of red ginger (Zingiber officinale Roxb. Var rubrum) on liver and lung histology male mice induced by paraquat. The research used completely randomized design and use of 6 treatment groups, i.e. control group (given distilled water and standard feed), PQ group (induced by paraquat 20 mg/kg per BW), group P1 (given paraquat and ethanol extracts of red ginger 200 mg/kg per BW), group P2 (given paraquat and ethanol extract of red ginger 400 mg/kg per BW), group P3 (given paraquat and ethanol extract of red ginger 600 mg/kg per BW), group P4 (given ethanol extract of red ginger extract 600 mg/kg per BW). The data obtained will be tested using One Way ANOVA and continued by Least Significant Difference (LSD) with a 95% confidence level. The results showed ethanol extract of red ginger effective against liver and lung histology male mice induced by paraquat. The results also showed ethanol extract of red ginger with a dose of 400 mg/kg per BW is effective in protecting the liver and lung from damage caused induced by paraquat.

scholarly journals Pengaruh Pemberian Kombinasi Ekstrak Etanol Daun Sidaguri (Sida rhombifolia L.) dan Rimpang Jahe Merah (Zingiber officinale Rosc.) pada Mencit Jantan Hiperurisemia

2018 ◽  
Vol 6 (2) ◽  
pp. 205
Author(s):  
Kinanthi Putri Rizki ◽  
Siti Muslichah ◽  
Indah Yulia Ningsih
Keyword(s):  
Uric Acid ◽  
Zingiber Officinale ◽  
Positive Control ◽  
Negative Control ◽  
Male Mice ◽  
Treatment Groups ◽  
Ginger Rhizome ◽  
Red Ginger ◽  
Sida Rhombifolia ◽  
Potassium Oxonate

  This study aimed to determine the effect of the combination of sidaguri leaves and red ginger rhizome extracts in uric acid levels of hyperuricemic male mice. Thirty-six mice were divided into nine groups including normal group, the positive control (+), negative control (-), extracts of four treatment groups with a variety of combinations and two groups of single extract. Hyperuricemia induction was performed by administering mixture melinjo 10% of the standard feed mice for 7 days dan potassium oxonate 250 mg/kg BB intraperitoneally at 2 hours before blood sampling. The results showed that the combination dose of sidaguri leaves of 50 mg/kg BB and red ginger rhizome 400 mg/kg BB had higher antihyperuricemia activity than other combinations in lowering uric acid levels of mice. Compounds may have antihyperuricemic activity were flavonoids, alkaloids, saponins, tannins, and terpenoids.   Keywords: sidaguri leaves, red ginger rhizome, antihyperuricemic activity, uric acid  

PERTUMBUHAN, KUANTITAS DAN KUALITAS RIMPANG JAHE (Zingiber officinale Roscoe) PADA CEKAMAN KEKERINGAN DI BAWAH NAUNGAN

2013 ◽  
Vol 14 (3) ◽  
Author(s):  
Lukita Devy ◽  
Winda Nawfetrias
Keyword(s):  
Drought Stress ◽  
Stress Condition ◽  
Field Capacity ◽  
Dry Weight ◽  
Zingiber Officinale ◽  
Opposite Trend ◽  
Zingiber Officinale Roscoe ◽  
Ginger Rhizome ◽  
Drought Stress Condition

This research studied the growth, quantity and quality of ginger rhizome under drought stress condition. The drought stress condition was 60% of soil field capacity. This experiment was arranged in randomized complete block designed. The treatments were drought stress periods (6, 4, 2 and 0 week before harvesting) with six replications. The result showed that drought stress period affected the quantity (rhizome dry weight) and quality (gingerol content) of ginger. Rhizome dry weight was decreased with the increase of drought stress period, while gingerol content showed opposite trend.

scholarly journals Growth Performance of Two Ginger (Zingiber officinale Roscoe) Varieties under Different Agroforestry Systems in Bangladesh

2020 ◽  
pp. 1-10
Author(s):  
S. Hossain ◽  
M. S. Rahman ◽  
K. N. Kona ◽  
M. S. Bari ◽  
N. Akter ◽  
...  
Keyword(s):  
Light Intensity ◽  
Open Field ◽  
Zingiber Officinale ◽  
Agroforestry Systems ◽  
Factor B ◽  
Zingiber Officinale Roscoe ◽  
Ginger Rhizome ◽  
Main Effect ◽  
Total Light

The experiments was conducted at a farmers’ field adjacent to the HSTU Research Farm, Dinajpur during 28th April to 13th December 2018 to evaluate growth and quality of two ginger (Zingiber officinale Roscoe) varieties under different tree such as ghoraneem, litchi and mango based Agroforestry systems. The experiment was two factors RCBD where Factor A (four Agroforestry systems) and Factor B (two ginger varieties). Factor A (Agroforestry system) were- T1=under Ghoraneem, T2= under Litchi, T3= under Mango and T4= Open field (control). Again, factor B (variety) were- V1= Deshiand V2= China. Therefore, the treatment combinations were T1V1, T1V2, T2V1, T2V2, T3V1, T3V2, T4V1 and T4V2. The experiment results revealed that the growth and quality of ginger were significantly varied by the main effect of different Agroforestry systems. The highest germination speed, plant height was higher under Ghoraneem (T1) but thehighest fresh rhizome weight (21600 kg/ha) was found under Mango based System (T3), whereas the highest dry rhizome weight (20%) was found under Open field condition (T4). The main effect of varieties on growth and quality of ginger were significantly varied. Germination speed, plant height, fresh rhizome weight was higher in deshi ginger (V1) but highest dry rhizome weight was found in china ginger (V2). The interaction effect of Agroforestry systems and ginger varieties was also significant. The highest germination found in T1V1.Again, the tallest plant was recorded in T1V2.The highest fresh rhizome weight (20865 kg/ha) was found in T3V1 but the highest dry rhizome weight was found inT4V1 (21.25 %). The relationship between light intensity and fresh ginger rhizome yield was inversely proportional. The highest ginger rhizome yield (21600 kg/ha) was found when the total light intensity was 115.50 LUX under Mango (T1) and the lowest ginger rhizome yield(18366 kg/ha) was when the total light intensity was 321.50 LUX in open field (T4).

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