scholarly journals Aggressiveness and Libido of Male Mus musculus L. in Ethanol Extract of Red Ginger (Zingiber officinale Roxb. var. Rubrum)

2019 ◽  
Vol 6 (1) ◽  
pp. 8-14
Author(s):  
Nida Nurhanifah ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Free Radicals ◽  
Ethanol Extract ◽  
Serum Testosterone ◽  
Zingiber Officinale ◽  
The Body ◽  
Male Mice ◽  
Ginger Extract ◽  
Treatment Groups ◽  
Randomized Design ◽  
Red Ginger

The residue of paraquat herbicides may cause human health problems. Paraquat causes the testosterone hormone to decline. Testosterone hormone affects aggressive and sexual behavior. It is caused by free radicals in the body. Free radicals can be non-reactive if in the body there are antioxidants. Red ginger could be used as an antioxidant because it has active phenolic compounds, such as arginine, gingerol, shogaol, zingerone, gingerdiol, and zingiber. Ginger could increase serum testosterone levels. The purpose of this research is to know the effect of red ginger ethanol extract on aggressiveness and libido of male mice induced by paraquat herbicide. This study used a Completely Randomized Design (RAL) consisting of six treatment groups with four replications each. Group P1 as control (aqua dest), P2 (paraquat at dose 20 mg/kg BM), P3, P4, P5 (paraquat with dose 20 mg/kg BM and red ginger extract at 200 mg/kg BM, 400 mg/kg BM, 600 mg/kg BM) and P6 (red ginger extract at 600mg/kg BM). Paraquat is given 2 times a week for 21 days and the red ginger extract is given daily for 35 days. The result of analysis with One-way ANOVA and continued BNT at 5% showed that giving of red ginger ethanol extract can increase aggressive behavior and libido of male mice induced paraquat herbicide.

scholarly journals Organ-Protective Effect of Red Ginger Extracts in Male Mice Induced by Paraquat

2019 ◽  
Vol 6 (2) ◽  
pp. 8-17
Author(s):  
Kamiliah Tsany ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Ethanol Extract ◽  
Zingiber Officinale ◽  
The Body ◽  
Control Group ◽  
Male Mice ◽  
Ginger Extract ◽  
Randomized Design ◽  
Significant Difference ◽  
Lung Histology ◽  
Red Ginger

Paraquat is a toxic compound that disrupts biochemical processes in the body, cell death, and multi-organ failure. The liver and lung are the target organ of paraquat toxicity. The body needs antioxidants to counteract free radicals. Red ginger (Zingiber officinale Roxb. Var rubrum) is a spice that contains antioxidants. This study was conducted to determine the effect of ethanol extract of red ginger (Zingiber officinale Roxb. Var rubrum) on liver and lung histology male mice induced by paraquat. The research used completely randomized design and use of 6 treatment groups, i.e. control group (given distilled water and standard feed), PQ group (induced by paraquat 20 mg/kg per BW), group P1 (given paraquat and ethanol extracts of red ginger 200 mg/kg per BW), group P2 (given paraquat and ethanol extract of red ginger 400 mg/kg per BW), group P3 (given paraquat and ethanol extract of red ginger 600 mg/kg per BW), group P4 (given ethanol extract of red ginger extract 600 mg/kg per BW). The data obtained will be tested using One Way ANOVA and continued by Least Significant Difference (LSD) with a 95% confidence level. The results showed ethanol extract of red ginger effective against liver and lung histology male mice induced by paraquat. The results also showed ethanol extract of red ginger with a dose of 400 mg/kg per BW is effective in protecting the liver and lung from damage caused induced by paraquat.

scholarly journals Boosting Sperm Count Using Red Ginger in Mice Induced by Paraquat Dichloride (1.1-dimethyl-4.4 bipyridinium)

2019 ◽  
Vol 6 (2) ◽  
pp. 1-7
Author(s):  
Siti Umairoh ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Sperm Count ◽  
Ethanol Extract ◽  
Reproductive Organs ◽  
Male Mice ◽  
Treatment Groups ◽  
Randomized Design ◽  
Significant Difference ◽  
Completely Randomized Design ◽  
Red Ginger ◽  
Difference Test

Paraquat dichloride (1.1'-dimethyl-4.4'-bipyridinium dichloride) was commonly herbicide used by most farmers in Indonesia. It raises herbicide-free radicals and affects male reproductive organs. It caused infertility such as a decrease in the number of spermatogenic cells. Fortunately, red ginger has capable of dealing with infertility problems. This study aims to see whether the ethanol extract of red ginger can increase the number of spermatocyte and spermatid cells induced by paraquat dichloride. This study uses a completely randomized design with 24 male mice were divided into six treatment groups with four replications. Group K as a control (H2O), J (Ginger 18 mg / ml), Pq (Paraquat 20mg / BB), P1 (Pq 20 mg / BB + EEJM 6 mg / ml), P2 (Paraquat 20mg / BB + EEJM 12 mg / ml) and P3 (Paraquat 20mg / BB + EEJM 18 mg / ml). Paraquat is given 2 times a week for 21 days, while the ethanol extract of red ginger added for 35 days. The number of cells spermatocyte and spermatid cells of male mice and performed analysis of variance (ANOVA) and Least Significant Difference Test (BNT) level of 5% observed as the parameter. The results showed that ethanol extract of red ginger 6, 12 and 18 mg/ml increased the number of spermatocyte and spermatid cells of male mice induced by paraquat dichloride.

scholarly journals The Utilization of Garlic (Allium sativum Linn) and Red Ginger (Zingiber officinale var rubra) Extract on The Growth of Broiler were Infected by Escherichia coli

2018 ◽  
Vol 5 (3) ◽  
Author(s):  
A W Isma ◽  
M Tafsin ◽  
Y L Henuk ◽  
N D Hanafi ◽  
Hamdan
Keyword(s):  
Escherichia Coli ◽  
Broiler Chickens ◽  
Allium Sativum ◽  
Zingiber Officinale ◽  
Ginger Extract ◽  
Tetracycline Antibiotics ◽  
E Coli ◽  
Randomized Design ◽  
Red Ginger ◽  
Alternative Antibiotic

This study aims to examine the effect of garlic (Allium sativum Linn) and red ginger (Zingiber officinale var rubra) extract on the growth of broiler chickens were infected by Escherichia coli. The design used in this study was a complete randomized design (CRD) with 6 treatments and 3 replications. Treatment consists of P0A = Control without infection; P0B = Control + E. coli infection; P1 = Infection E. coli + tetracycline antibiotics 0.05%; P2 = Infection E. coli + garlic extract (Allium sativum Linn) (1%); P3 = Infection E. coli + red ginger extract (Zingiber officinale var rubra) (1%); P4 = Infection E. coli + garlic (Allium sativum Linn) and red ginger (Zingiber officinale var rubra) extract (1%). The results showed that the effect of garlic and red ginger gave significant influence (P <0,05) to growth of broiler were infected by Escherichia coli. The combination of garlic (Allium sativum Linn) and red ginger (Zingiber officinale var rubra) extract has the highest influence of other activities. It was concluded that giving of garlic and red ginger extract give influence to growth of broiler were infected by Escherichia coli and can be used as alternative antibiotic.

scholarly journals PENGARUH PEMBERIAN EKSTRAK ETANOL JAHE MERAH (Zingiber Officinale Roxb var Rubrum) TERHADAP KUANTITAS DAN KUALITAS SPERMATOZOA MENCIT JANTAN (Mus musculus L.) YANG DIINDUKSI PARAQUAT DIKLORIDA

2019 ◽  
Vol 5 (2) ◽  
pp. 47-54
Author(s):  
Dian Anggraini ◽  
Sutyarso Sutyarso ◽  
M. Kanedi ◽  
Hendri Busman
Keyword(s):  
Body Weight ◽  
Mus Musculus ◽  
Sperm Count ◽  
Zingiber Officinale ◽  
The Body ◽  
Test Material ◽  
Control Group ◽  
Ginger Extract ◽  
Wide Range ◽  
Red Ginger

Paraquat is one of the chemicals that contributes to increasing pollution Indonesia. The careless use of paraquat can increase production of ROS (Reactive Oxygen Species), resulting in damage to a wide range of vital organs and reproductive system disorders such as infertility. ROS in the body can be captured by antioxidants. Red Ginger contains high antioxidants because there are active phenolic compounds such as gingerol, shagaol, zingeron, ginggerdiol, and zingibren which are proven to protect body cells from damage caused by ROS. This study was aimed to test the effectiveness of red ginger extract (Zingiber officinale Roxb. Var. Rubrum) on the quantity and quality of sperm in male mice (Mus musculus L.) induced by paraquat dichloride.This research uses a completely randomized design and is divided into six treatment groups with each four replications: K1 as the control group (only given H2O); K2 (paraquat induced a dose of 20 mg/kg Body Weight (BW) without the administration of the test substances); K3; K4; K5 (paraquat induced a dose of 20 mg/kg Body Weight (BW) and was given a red ginger extract at a dose of consecutive succession 6 mg / ml, 12 mg / ml, 18 mg / ml) and K6 (Only given a test material the red ginger extract as much as 18 mg / ml). Paraquat was given 2 times a week for 21 days and the red ginger extract was given for 35 days. The results of analysis by One-way ANOVA followed LSD at 5% significance level showed the ethanolic extract of red ginger can increase the sperm count, motility, viability and Morphology sperm of mice induced by the paraquat diklorida.

scholarly journals EFFECT OF RED GINGER EXTRACT (Zingiber officinale Var Rubrum) ON CHEMICAL AND ORGANOLEPTICS QUALITY OF AMBON CURUP BANANA WET “SALE”

2019 ◽  
Vol 9 (1) ◽  
pp. 28-36
Author(s):  
Wuri Marsigit ◽  
Laili Susanti ◽  
Lia Marzalena
Keyword(s):  
Immersion Time ◽  
Consumer Preference ◽  
Zingiber Officinale ◽  
Ash Content ◽  
Chemical Quality ◽  
Ginger Extract ◽  
Average Value ◽  
Randomized Design ◽  
Red Ginger

ABSTRACTQuality improvement  of sale banana ambon curup was necessary to increase chemical and organoleptics quality and consumer preference. The  purpose  of  this  study  was  to  determine  the  effect  of  variations  in  theconcentration   of   red   ginger   juice   and   the   length   of   immersion   on  chemical   quality, microbiology and organoleptic wet sale of banana ambon curup. By using (RAL) 2 factorial randomized design, the concentration of red ginger juice was 5%, 10% and 15% with a time of immersion for 20 and 10 minutes. The analytical method used was ANOVA. The results of the study found that sucrose levels were 37.56% to 57.54 %, the water content was 36.66% and 38.33%, ash content was 1.47 % to 1.87 %.  The  panelists  preferred  the  average  value  of  the  whole (texture, aroma, and tate)  was  found  in  the  P1T1 sample  with  a  treatment  of  red  ginger  concentration  of  0.05%  and  immersion  time  for  10 minut  

scholarly journals Pengaruh Pemberian Ekstrak Jahe Merah (Zingiber Officinale R.) Terhadap Susut Masak Dan Nilai pH Pada Daging Ayam Ras Petelur Afkir dengan Konsentrasi dan Lama Perendaman yang Berbeda

bionature ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Rusdi Rusdi ◽  
Munir Munir ◽  
Nurhaeda Nurhaeda
Keyword(s):  
Ph Value ◽  
Animal Husbandry ◽  
Zingiber Officinale ◽  
Average Effect ◽  
Ginger Extract ◽  
Factor B ◽  
Animal Product ◽  
Randomized Design ◽  
Natural Enzyme ◽  
Red Ginger

Abstract. This study aims to determine the effect of red ginger extract (Zingiber Officinale R) on the pH value and cooking losses. The study was conducted in January 2018 at the Laboratory of Animal Product Processing Technology, Faculty of Agriculture and Animal Husbandry using a factorial Completely Randomized Design (RAL), where factor A (level of red ginger extract and papaya fruit skin) 0%, 25%, 50%, 75% were interacted with a factor B (soaking time) of 5 minutes, 10 minutes and 15 minutes which was repeated three times. The results showed no significant effect (P> 0.05) on the value of cooking losses. The treatment of using red ginger extract (Zingiber Officinale R) as a natural enzyme that had no significant effect (P> 0.05) on the pH value. In factor A (extract level) to the pH value, this can be seen from the average effect of A is J0 = 6.24%, J1 = 6.28%, J2 = 6.26% and J3 = 6.40%. In factor B (duration of immersion) does not affect the pH value that can be seen from the average effect of B is W1 = 6.14, W2 = 6.41 and W3 = 6.34. The conclusion of this study was that the administration of red ginger extract in cooking losses could decrease in the treatment of P3 = 30.46% and the pH did not significantly affect the immersion long red ginger extract.Keywords: Red Ginger Extract, Natural Enzymes, pH Value and Shrinkage of Cook.

scholarly journals Pengaruh Pemberian Kombinasi Ekstrak Etanol Daun Sidaguri (Sida rhombifolia L.) dan Rimpang Jahe Merah (Zingiber officinale Rosc.) pada Mencit Jantan Hiperurisemia

2018 ◽  
Vol 6 (2) ◽  
pp. 205
Author(s):  
Kinanthi Putri Rizki ◽  
Siti Muslichah ◽  
Indah Yulia Ningsih
Keyword(s):  
Uric Acid ◽  
Zingiber Officinale ◽  
Positive Control ◽  
Negative Control ◽  
Male Mice ◽  
Treatment Groups ◽  
Ginger Rhizome ◽  
Red Ginger ◽  
Sida Rhombifolia ◽  
Potassium Oxonate

  This study aimed to determine the effect of the combination of sidaguri leaves and red ginger rhizome extracts in uric acid levels of hyperuricemic male mice. Thirty-six mice were divided into nine groups including normal group, the positive control (+), negative control (-), extracts of four treatment groups with a variety of combinations and two groups of single extract. Hyperuricemia induction was performed by administering mixture melinjo 10% of the standard feed mice for 7 days dan potassium oxonate 250 mg/kg BB intraperitoneally at 2 hours before blood sampling. The results showed that the combination dose of sidaguri leaves of 50 mg/kg BB and red ginger rhizome 400 mg/kg BB had higher antihyperuricemia activity than other combinations in lowering uric acid levels of mice. Compounds may have antihyperuricemic activity were flavonoids, alkaloids, saponins, tannins, and terpenoids.   Keywords: sidaguri leaves, red ginger rhizome, antihyperuricemic activity, uric acid  

scholarly journals ISOLASI SENYAWA AKTIF DAN UJI AKTIVITAS EKSTRAK JAHE MERAH (ZINGIBER OFFICINALE) SEBAGAI IMUNOMODULATOR

2021 ◽  
Vol 3 (2) ◽  
pp. 77-91
Author(s):  
Masniah Masniah ◽  
Jafril Rezi ◽  
Ahmad Purnawarman Faisal
Keyword(s):  
Lymphocyte Proliferation ◽  
Ethanol Extract ◽  
Zingiber Officinale ◽  
Immunomodulatory Activity ◽  
Ginger Extract ◽  
Immunostimulatory Activity ◽  
Macrophage Cells ◽  
Macrophage Phagocytosis ◽  
Red Ginger

Red ginger (Zingiber officinale) contains many chemical compounds that have many activities. This study aims to determine the active compounds of Zingiber officinale and immunomodulatory activity that can increase the phagocytosis of macrophage cells and lymphocyte cell proliferation. Red ginger extract compounds were identified using GC-MS. The parameters of immunostimulatory activity were macrophage phagocytosis and lymphocyte proliferation, the preparations were made in several extract concentrations. This research is an experimental study in the laboratory. The research included fresh red ginger, made into ethanol extract, dried. The results were made a suspension, the extract was then given to macrophage cells (phagocytosis testing) and lymphocyte cells (proliferation testing) in vitro to test the immunomodulatory effect. The results showed that the most active extract in macrophage phagocytosis activity was the extract concentration of 500 ppm. While the activity of lymphocyte proliferation was shown by the concentration of group A (Cell, 500 ppm extract, MK, Engerik). The active compound contained in the ethanol extract of red ginger is thought to be Geraniol

scholarly journals Effectiveness of Extracts of Garlic (Allium sativum L) and Red Ginger (Zingiber officinale var rubra) as Escherichia coli Control in Broiler Chicken

2018 ◽  
Vol 5 (3) ◽  
Author(s):  
R N Damanik ◽  
M Tafsin ◽  
A H Daulay ◽  
E Mirwandhono ◽  
T H Wahyuni
Keyword(s):  
Escherichia Coli ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Allium Sativum ◽  
Zingiber Officinale ◽  
Ginger Extract ◽  
E Coli ◽  
Randomized Design ◽  
Escherichia Coli Bacteria ◽  
Red Ginger

This study aims to determine the effectiveness of extracts of garlic (Allium sativum L.) and ginger (Zingiber officinale) on the growth of broiler chickens infected with E. coli. The design used in this study was a Completely Randomized Design with 6 treatments and 3 replications. The treatment consisted of P0A = control without infection, P0B = control + E. coli infection, P1 = E. coli infection + 0.05% tetracycline antibiotics, P2 = E. coli infection + 1% garlic (Allium sativum L.) extract , P3 = E. coli infection + 1% ginger (Zingiber officinale) extract and P4 = E. coli infection + garlic (Allium sativum L) extract and 1% ginger (Zingiber officinale). The results showed that the administration of garlic and ginger extract had a significant effect (P <0.05) on the decrease in the number of Escherichia coli bacteria in broiler chicken feces. The combination of extracts of garlic (Allium sativum L.) and red ginger (Zingiber officinale) has the most effective effect compared to garlic and ginger extract alone. It was concluded that the administration of extracts of garlic and ginger could be used as Escherichia coli control in broiler chickens.

scholarly journals Analysis of antioxidant activity, total phenolic and flavonoid contents of ethanol extract of Litsea cubeba Lour. Bark

2021 ◽  
Vol 332 ◽  
pp. 08005
Author(s):  
Aminah Dalimunthe ◽  
Dewi Pertiwi ◽  
Mahatir Muhammad ◽  
Denny Satria
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Ethanol Extract ◽  
The Body ◽  
Total Flavonoid ◽  
Total Phenolic ◽  
Antioxidant Power ◽  
Litsea Cubeba ◽  
Ferric Reducing Antioxidant Power ◽  
Phenolic And Flavonoid

Free radicals also play a role in the pathology of various degenerative diseases such as cancer, rheumatism, coronary heart disease, cataracts, and others. Free radicals can come from within the body (endogenous) and outside the body (exogenous). Litsea cubeba (Lour,) is a Lauraceae family plant which have contents volatile oils which used as antimicrobial, anticancer on breast cancer, pesticide, antideppressants, antiinflammation, antioxidant, and neuro pharmacology. The extract was prepared using water with the soxhletation method. The antioxidant activity was determined with the 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2’-Azinobis [3-ethylbenzothiazoline-6)-sulfonic acid] -diammonium salt (ABTS) and Ferric Reducing Antioxidant Power (FRAP) methods. Total flavonoid and total phenolic content were determined with colorimetric methods. Antioxidant activity measured as IC50 was 23.37 ± 0.42 µg/mL; 111.21 ± 0.42 and 109.01 ± 0.28 respectively. The extract was found to contain high levels of total phenolic (282.93 ± 0.33 mg GAE/g) and total flavonoid 7.49 ± 0.51 mg QE/g). The results reveal that ethanol extract of Litsea cubeba Lour. Bark has antioxidant potential. The further analysis is to isolation antioxidant compound.

Sign in / Sign up

Export Citation Format

Share Document