scholarly journals Analisis Antalgin dalam Jamu Pegal Linu yang Dijual di Pasar Beringharjo Yogyakarta

2017 ◽  
Vol 4 (1) ◽  
pp. 29
Author(s):  
Siti Fatimah ◽  
Muji Rahayu ◽  
Debi Firma Indari
Keyword(s):  
Herbal Medicine ◽  
Traditional Medicine ◽  
Plant Material ◽  
Diclofenac Sodium ◽  
Research Data ◽  
Negative Results ◽  
Traditional Market ◽  
Animal Material ◽  
Layer Chromatography ◽  
Positive Results

Background: Traditional medicine is an ingredient or ingredients in the form of plant material, animal material, mineral materials, preparation essence (galenic), or mixtures of these materials that have historically been used for treatment, and can be applied according to the prevailing norms in society. Traditional medicine  is often chosen as a remedy for health care is herbal, because herbal medicine is a health drink. Chemicals drugs were added by the makers of herbal medicine with the intent may be to increase the efficacy of herbal medicine and herbal medicine provide more instant effect, it is becoming a source of danger herbs. BPOM many find herbs aching pains who defiled chemical medicines like phenylbutazone, methampyrone, diclofenac sodium, piroxicam, paracetamol, prednisone, or dexamethasone. Chemicals a drug it is set in PERMENKES 007 of 2012. Methods: This research is to describe the whether or not of chemicals in the antalgin sold in the Beringharjo traditional market Yogyakarta. The method used to test the lab using thin layer chromatography. Research data presented in terms of percent. Results: Research is obtained value Rf sample 0.63 until 0.8 one sampel having the value Rf and fluorescence equal to standard methampyrone. Value Rf standard methampyrone 0,78 and red purple fluorescence. Conclusion: There are methampyrone in herbal medicine aching pains sold in the Beringharjo traditional market to a presentation positive results as many 8.3%  and negative results 91.7%.

scholarly journals Bacteria Identification In Traditional Sauce (Sambal) At The Restaurants Nearby The Traditional Markei Of Gorontalo City

2021 ◽  
Vol 2 (1) ◽  
pp. 11-18
Author(s):  
Ana Pepiana ◽  
Laksmyn Kadir ◽  
Agusrianto Yusuf
Keyword(s):  
Fecal Coliform ◽  
Sampling Technique ◽  
Coliform Bacteria ◽  
Most Probable Number ◽  
Probable Number ◽  
Fecal Coliform Bacteria ◽  
Negative Results ◽  
Escherchia Coli ◽  
Traditional Market ◽  
Positive Results

The unsafe food will cause the health problems in the community. Sambal which is known as the traditional sauce is a sauce made from chilies that are crushed until the water content comes out, giving it a spicy taste. Furthermore, Sambal is processed in a simple way so that it can leac to the contamination of microorganisms such as Coliform bacteria contamination. This study aims to determine the presence of Coliform bacteria contamination in Sambal at the supermarket nearby the traditional market in Gorontalo City. This research is a descriptive study using a qualitative approach. It examines the existence of Coliform bacteria using the Most Probable Number (MPN) method. The population in this study were 14 samples with the sampling technique by accidental sampling. Coliform bacteria examination results show that Sambal sample is found with positive results contaminated with Coliform bacteria, namely 11 samples with a percentage of 78.6% and negative results of 3 samples with a percentage of 21.4%. Based on the results, it can be concluded that a positive result was found consisting of 1 sample of coliform fekal bacteria, in this case the bakteri Escherchia coli. bacteria, and 10 samples from the non-fecal coliform bacteria.

scholarly journals Phytochemical Study and In vitro Anthelminthic Properties Studies of the Trunk Barks Aqueous Extract from Acacia Nilotica

2018 ◽  
Vol 10 (01) ◽  
Author(s):  
A. G L Boly ◽  
M. B. Belemlilga ◽  
A. Traore ◽  
S. Ouedraogo ◽  
E T I P Guissou
Keyword(s):  
Traditional Medicine ◽  
Aqueous Extract ◽  
Plant Material ◽  
Intestinal Parasites ◽  
Gastrointestinal Parasites ◽  
Acacia Nilotica ◽  
Phytochemical Study ◽  
Animal Material ◽  
Chemical Groups

The present study was to estimate the in vitro anthelminthic effect of the aqueous extract of the trunk barks of Acacia nilotica var. adansonii, plant used in this traditional medicine against gastro- intestinal parasites. Trunk barks of Acacia nilotica var. adansonii were used as plant material, eggs and adults worms of Haemonchus contortus were the animal material used. The adult worms and the eggs were put in contact with increasing concentrations of the extract. A phytochemical screening of the plant material was also performed. This study revealed the presence of chemical groups with anthelminthic properties such as tannins, triterpenics, saponosides in the aqueous extract. The vermicide effect was indicated by the lethal concentration of 50% (LC50) of adult worms equal to 1.28 mg / mL compared to the levamisole LC50 which was 3.25 mg / mL. The rate of eggs hatching inhibition was 93.84 % at the extract concentration of 0.1 mg / mL. Anthelminthic properties of Acacia nilotica var. adansonii would be real, which justifies its use in traditional medicine for the treatment of gastrointestinal parasites

Identifikasi Sediaan Jamu Kuat yang Beredar di Kecamatan Banguntapan dan Pleret Kabupaten Bantul dengan Metode KLT

2019 ◽  
Vol 14 (2) ◽  
pp. 103
Author(s):  
Dewi Umniyatul ◽  
Dwi Kurniawati Sambodo
Keyword(s):  
Herbal Medicine ◽  
Thin Layer ◽  
Ethyl Acetate ◽  
Thin Layer Chromatography ◽  
Silica Gel ◽  
Plant Material ◽  
Uv Light ◽  
Sildenafil Citrate ◽  
Quota Sampling ◽  
Layer Chromatography

Background: Traditional herbs are ingredients or herbs in the form of plant material, animal ingredients, mineral ingredients, galenic preparations or mixtures of these ingredients, it has been used as medicine traditionally.Objective: This study is aimed to Identify of Sildenafil Citrate on “Jamu Kuat” (Herbal Medicine) products.Methods: This type of research was descriptive and the sample was determined by quota sampling. The method used Thin Layer Chromatography (TLC) which was a physicochemical method. There were seven samples were extracted by the soxhletation method until a thick extract was obtained to be spotted in the quite phase of TLC silica gel F254. The motion phase used to identify sildenafil citrate was chloroform: ethyl acetate (6: 4). Spots detection was done by observation under UV light 366 nm and the spots that appeared were calculated of Rf value and compared with the comparable Rf value of sildenafil citrate.Results: From this study, there were samples containing sildenafil citrate. Sample C with a sample Rf value of 0.75 and sample D with Rf value of sample 0.78 and a comparable Rf of sildenafil citrate 0.77.Conclusion: The seven samples of “Jamu Kuat” contained sildenafil citrate in Banguntapan and Pleret Districts, Bantul Regency. Keywords: Jamu Kuat (Herbal Medicine), Sildenafil citrate, TLC

scholarly journals Chemical detections of active compounds in Melilotus indica extracts

2009 ◽  
Vol 3 (1) ◽  
pp. 130-140
Author(s):  
Faisal K. Mutasher ◽  
Ghazi M. Aziz ◽  
Amani A.W . Abdul-Razzak
Keyword(s):  
Phosphate Buffer ◽  
Volatile Oils ◽  
Buffer Solution ◽  
Active Compounds ◽  
Buffer Solutions ◽  
Negative Results ◽  
Sodium Phosphate Buffer ◽  
Crude Extracts ◽  
Layer Chromatography ◽  
Positive Results

The crude extracts of the leaves of melilotus indica which collected in two dates (midFebruary, mid March) have been prepared by three solvents (Distilled water, ethanol 80% and chloroform) and three buffer solutions (Sodium acetate buffer, Sodium phosphate buffer and Tris-hydrochloric acid buffer), the greater percentage of crude extracts achieved by phosphate buffer which were 47.3% and 29.2% for second and first dates, respectively, while the lowest percentage of crude extracts achieved by chloroform extracts which were 13.2% and 10.0% for second and first dates, respectively. The qualitative chemical detections for active compounds in crude extracts revealed a positive results for the saponins, tannins, coumarins, flavones and glycosides, while the detections revealed a negative results for the alkaloids, resins and volatile oils. The active compounds in crude extracts prepared by solvents and buffer solutions were studied by thin layer chromatography (TLC), the solvent extracts were contains five compounds with relative flow (RF) 0.65, 0.4 for coumarin and umbelliferon, respectively, and 0.5, 0.27, 0.2 which belong to simple coumarins compounds in melilotus indica, while buffer solution extracts were contains two compounds with RF value 0.65 and 0.4 for coumarin and umbelliferon, respectively.

scholarly journals Analysis of Chemical Materials of Sodium Diclofenac Drugs In Legal Private Food Which is Different in Makassar

2018 ◽  
pp. 311-317
Author(s):  
Masdiana Tahir ◽  
St Maryam ◽  
Andi Wahdania
Keyword(s):  
Herbal Medicine ◽  
Mobile Phase ◽  
Blood Circulation ◽  
Diclofenac Sodium ◽  
Sodium Content ◽  
Positive Sample ◽  
The Body ◽  
Chemical Content ◽  
Layer Chromatography ◽  
Chemical Materials

Sore herbal medicine is one of the traditional medicine products that many people interested in due to it can eliminate the muscle pain and arthritis, accelerate blood circulation, strengthen body endurance and eliminate pain through out the body. One of the medicinal chemicals which is commonly added in thesore herbal medicine is diclofenac sodium. This study aimed to analyze the chemical content of diclofenac sodium drug in the sore herbal medicine dosage fom. There were 7 herbal medicine this research is 7 kinds of brand circulating in Makassar city with the criteria most demand by the society. Qualitative analysis of the diclofenac sodium drug was conducted by thin layer chromatography (TLC), used silica gel stationary phase and the mobile phase of ethyl acetate : gacial acetic acid : toluene (60:40:1). The result showed that A, C and G positive sample contain dicklofena sodium with Rf value equal to diclofenac sodium standard, Rf = 0,69. The quantitative analysis by UV-Vis spectrophotometry at the wavelength 280 nm with variation of concentration 4, 6, 8, 10, 12, 14 and 16 ppm was obtained diclofenac sodium content for sample A with 154 mg/g, for C 28,302 mg/g and sample G 6,908 mg.g.   Keyword: Diclofenac Sodium, Rheumatic Paint, Spectrophotometry UV-Vis  

scholarly journals Ethnobotanical Study of Zingiberaceae Rhizomes as Traditional Medicine Ingredients by Medicinal Plant Traders in the Pancur Batu Traditional Market, North Sumatera, Indonesia

2021 ◽  
Vol 4 (2) ◽  
pp. 78-95
Author(s):  
Marina Silalahi ◽  
Nisyawati ◽  
Endang C. Purba ◽  
Daichiro W. Abinawanto ◽  
Riska S. Wahyuningtyas
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Traditional Medicine ◽  
Research Data ◽  
Ethnobotanical Study ◽  
Main Ingredient ◽  
Traditional Markets ◽  
Traditional Market ◽  
Semi Solid ◽  
North Sumatra

Traditional markets are places for buying and selling medicinal plants and are a source of ethnobotany research data.  This study aims to determine the uses and characteristics of Zingiberaceae rhizomes have been used as traditional medicine and traded in the traditional market of Pancur Batu, North Sumatra. This research was conducted with an ethnobotany approach through surveys, interviews and observation participatory. The respondents are all medicinal plants traders in the Pancur Batu traditional market. The things that were asked of the traders included local names, special characters, benefits, and how to recognize the rhizome. The medicinal plant traders in the Pancur batu traditional market have been utilized and traded as many as 10 species of Zingiberaceae rhizome, most of them belonging Curcuma and Zingiber genera. The characteristics of rhizomes are recognized by traders through their size, color, and aroma. The cross-section of the rhizomes of each species is different in structure and color which is used as the main marker for each species. Rhizoma Zingiberaceae is used as the main ingredient for tawar (semi-solid medicinal herbs consumed by brewing), parem (solid medicinal ingredients), and oukup (traditional Karo sauna). The rhizome aroma of each species belonging Zingiberaceae is very distinctive which is related to the content of essential oils. The use of Zingiberaceae rhizomes as tawar and parem ingredients needs to be studied further so that they are developed into standardized herbs.

scholarly journals IDENTIFIKASI DAN STUDI POLA FRAGMENTASI JAMU TERKONFIRMASI FENILBUTAZON MENGGUNAKAN LIQUID CHROMATOGRAPHY MASS SPECTROSCOPY (LCMS)

2020 ◽  
Vol 10 (2) ◽  
pp. 243
Author(s):  
Muhammad Taupik ◽  
Endah Nurrohwinta Djuwarno ◽  
Moh Adam Mustapa ◽  
Muhamad Handoyo Sahumena
Keyword(s):  
Liquid Chromatography ◽  
Herbal Medicine ◽  
Traditional Medicine ◽  
Mass Spectroscopy ◽  
Retention Time ◽  
Fragmentation Pattern ◽  
Traditional Herbal Medicine ◽  
Synthetic Drugs ◽  
The Republic ◽  
Layer Chromatography

The Jamu is one type of traditional herbal medicine that still popular among the community until now. In twenty years  often found the jamu containing synthetic drugs. Drug chemical which is commonly added to this traditional herbal  medicine  include  the  class  of  drugs  of  NAISD’s  namely  phenylbutazone. This  study  was  conducted  to  determine  the  possibility  of  presence  of phenylbutazone in the Jamu. The beginning of this study by initial screening using Thin Layer Chromatography (TLC) method. The results showed that 4 of the 6 samples of the positive contain phenylbutazone based TLC method.  These 4 samples were then analyzed using the Liquid Chromatography Mass Spectroscopy (LCMS) method. The stationary phase is Octadecyl Silica (C18) and the Mobile Phase are ultrapure water motion: acetonitrile (90 : 10% v/v) with isocratic elution system and positive ion mode. Based on LCMS chromatogram data, the retention time (Rf) of phenylbutazone is 1.89 minutes. The retention time of samples same with  the retention time of phenylbutazone. The next approach, based on the fragmentation pattern of Mass Spectroscopy. Based on mass spectrum data, there are 2 formed fragmentation paths. The first pattern is the fragmentation process of phenylbutazone (309 m / z), forming 2-butylmalonaldehyde (129 m / z) and 1,2-diphenylhydrazine (184 m / z).  The second fragmentation pattern was obtained by the Indol 3-H pathway, producing 3-butylidene-3H-indol-2-olate fragments (188 m / z) and 3H-indole-2,3-diide (114 m / z). Based on the analysis using the LCMS method, four samples containing phenylbutazone, Samples A, C, D and E. The four samples should not be allowed to be traded and consumed for  violating  the  Regulation  of  the  Minister  of  Health  of  the  Republic  of  Indonesia  No  006  of  2012chapter  33  and  chapter  37  on  the  industry  and  traditional  medicine  business  that  traditional  medicine  is  prohibited  to contain chemicals from the isolation or synthetic drug efficacious.

scholarly journals Jamu: Javanese Doping During the Covid-19 Pandemic

2021 ◽  
Vol 2 (2) ◽  
pp. 92-98
Author(s):  
Akhodza Khiyaaroh ◽  
Atik Triratnawati
Keyword(s):  
Immune System ◽  
Herbal Medicine ◽  
Traditional Medicine ◽  
Secondary Data ◽  
Sampling Technique ◽  
Research Data ◽  
Purposive Sampling ◽  
As Doping ◽  
Immune Booster

Jamu is a part of traditional medicine that draws many people's attention today. This can be seen in the increasing consumption of jamu in Indonesian society. This increase can be influenced by the decision of the Indonesian people to consume jamu as an effort to prevent Covid-19. This study revealed the reasons behind the choice of jamu as an effort to prevent Covid-19 in some Indonesian people, especially in rural Javanese people where jamu is very closely related to their lives. This research was conducted in Mojorejo Village, Kebonsari District, Madiun Regency by involving 20 informants obtained through purposive sampling technique. This research was conducted from April to June 2021. The ethnographic method was used to enable the researchers to dig deeper into the informants' experiences regarding herbal medicine. The researchers analyzed the research data by coding and included secondary data to enrich the findings.Rural Javanese people choose jamu as doping during the Covid-19 pandemic for three reasons, including the tradition of drinking jamu, its immune booster properties, and the 3M (mudah, murah, manjur) [Easy, Cheap, Effective] aspects of jamu. Jamu ingredients that include ginger, curcuma, aromatic ginger, turmeric, and tamarind are believed to be able to boost their immune system during the pandemic.

Critical Evaluation of Impedance Phlebography for the Diagnosis of Deep Vein Thrombosis

1974 ◽  
Vol 31 (02) ◽  
pp. 273-278
Author(s):  
Kenneth K Wu ◽  
John C Hoak ◽  
Robert W Barnes ◽  
Stuart L Frankel
Keyword(s):  
Deep Vein Thrombosis ◽  
False Positive ◽  
False Negative ◽  
Critical Evaluation ◽  
Original Method ◽  
Vein Thrombosis ◽  
Negative Results ◽  
False Negative Results ◽  
Deep Vein ◽  
Positive Results

SummaryIn order to evaluate its daily variability and reliability, impedance phlebography was performed daily or on alternate days on 61 patients with deep vein thrombosis, of whom 47 also had 125I-fibrinogen uptake tests and 22 had radiographic venography. The results showed that impedance phlebography was highly variable and poorly reliable. False positive results were noted in 8 limbs (18%) and false negative results in 3 limbs (7%). Despite its being simple, rapid and noninvasive, its clinical usefulness is doubtful when performed according to the original method.

Comparative Study of the Biologically Active Substances Composition and Content in Meadowsweet (Filipendula ulmaria (L.) Maxim) Crude Herbal Drugs (Herb, Leafs, Flowers) of Russian Origin

2018 ◽  
Vol 9 (3) ◽  
Author(s):  
Dmitry Olegovich Bokov ◽  
Tatyana Yuryevna Kovaleva ◽  
Valentina Alekseevna Ermakova ◽  
Daria Aleksandrovna Trashchenkova ◽  
Ekaterina Anatolievna Dorovskih ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Neurotropic Activity ◽  
Comparative Investigation ◽  
Biologically Active ◽  
Total Flavonoids ◽  
Herbal Drugs ◽  
Filipendula Ulmaria ◽  
Pharmacopoeial Monograph ◽  
Total Extractives ◽  
Layer Chromatography

Filipendula ulmaria (L.) Maxim. (Meadowsweet) is known in traditional medicine as anti-inflammatory, wound-healing,astringent and antibacterial remedy. However recent studies show that it also has neurotropic activity. In Russia meadowsweet flowers are used as crude herbal drugs (temporary pharmacopoeial monograph 42-1777-87), also leafs and herb are used in the traditional medicine. Objective of the study was to carry out comparative investigation of composition and content of major biologically active compounds (BAC) in Filipendula ulmaria herb, flowers and leafs by thin-layer chromatography, differential spectrophotometry with aluminum chloride reagent (total flavonoids in terms of rutoside), gravimetry (total extractives, extracted by water), permanganatometric titration (total tannins in terms of tannin). Rutoside, tannin, gallic acid and salicylic acid were identified in Filipendula ulmaria herb, flowers and leafs by TLC. Also we analyzed content of substances extracted by water, flavonoids and tannins. Total extractives, extracted by water in F. ulmaria herb is 13.12±0.10%, in leafs – 13.98±0.37%, in flowers – 18.09±0.17%. Total tannins in F. ulmaria herb is 11.87±0.47%, in leafs – 12.06±0.18%, in flowers – 12.26±0.29%. Total flavonoids in F. ulmaria herb 4.34±0.17%, in leafs – 6.98±0.23%, in flowers – 11.75±0.57%. The obtained data will be used for development of a pharmacopoeial monograph project "Filipendula ulmaria (L.) Maxim., herba" for inclusion in the State Pharmacopoeia of the Russian Federation.

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