scholarly journals Prevalence of peripheral neuropathy in diabetes mellitus and its association with therapy, ethnicity and duration of diabetes mellitus

2018 ◽  
Vol 10 (1) ◽  
pp. 72-76
Author(s):  
Dipesh Karki ◽  
Amar Nagila ◽  
Niraj Dhakal ◽  
Sumit Chhetri
Keyword(s):  
Diabetes Mellitus ◽  
Peripheral Neuropathy ◽  
Statistical Tests ◽  
Demographic Data ◽  
Categorical Variables ◽  
P Value ◽  
Diabetic Patients ◽  
Perception Threshold ◽  
Cross Sectional ◽  
Duration Of Diabetes

Background: Diabetic peripheral neuropathy (DPN) is a most common micro vascular complication of diabetes posing significant morbidity and mortality with early and insidious onset. Studies has variably pointed that older age, gender, duration of diabetes, dyslipidemia, are linked with development of DPN. Aims and Objectives: To determine the prevalence of neuropathy in diabetic patients and see its link with age, gender, duration of diabetes, therapy and ethnicity. Materials and Methods: This is a cross-sectional study involving 110 clinically diagnosed diabetic patients, meeting the inclusion criteria. Basic demographic data were taken during clinical examination. Presence of degree of neuropathy was screened by measuring vibration perception threshold using Biothesiometer. Data was entered on SPSS and were categorized, necessary non parametric statistical tests were applied to these categorical variables as needed. The level of significance was set at p value less than 0.05. Results: Presence of neuropathy was measured in 110 diabetic patients. The overall prevalence of DPN was 45.45%. Frequency of neuropathy was higher with increase in age with 72.7% in more than 60 years of age and 23.5% in less than or equal to 40 years of age group (p=0.007). Similarly, the increasing trend of DPN with increase in duration of DM was evident in this study with DPN present in more than 55% of patients with more than 5 years of diabetes(p=0.004). Conclusion: The prevalence rate of DPN in diabetes was observed to be higher (45.45%). Our result suggested that DPN is associated with old age and the duration of diabetes mellitus. Asian Journal of Medical Sciences Vol.10(1) 2019 72-76

scholarly journals The result of treadmill test in asymptomatic type 2 diabetes mellitus

2017 ◽  
Vol 3 (6) ◽  
pp. 166 ◽  
Author(s):  
Anil Shrinivasrao Joshi ◽  
Chandrakant Gunaji Lahane ◽  
Akshay Arvind Kashid
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Early Detection ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Asymptomatic Patients ◽  
Cardiovascular Morbidity And Mortality

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">To study the prevalence of silent myocardial ischaemia in asymptomatic patients with type 2 DM</span>.</p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The present study was conducted in the Govt. Medical College and Hospital Aurangabad. During December 2012 to November 2014 with 50 patients. It was two year cross sectional study with the patients of asymptomatic type 2 diabetes mellitus without clinical and electrocardiographic evidence of coronary artery disease. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">12 (24%) out of 50 subjects had positive TMT. It correlated with years of duration of diabetes (9 positive TMT cases with duration of diabetes more than 10 years). 5 (25%) out of 20 had serum cholesterol levels &gt;240, Number of positive TMT were higher in patients with LDL &gt;160 [5 (25%) out of 20]</span>.</p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Diabetic patients are at very high risk for cardiovascular morbidity and mortality. Early detection of IHD is very important so that pharmacological therapy, which may improve outcome, can be established. Tread mill exercise TMT being a non-invasive test with high safety, has an important role in early detection of IHD. It is recommended that TMT should be a part of routine management in asymptomatic patients with type II DM. </span></p>

scholarly journals A Study to Evaluate the Quality of Life of Patients with Diabetes Mellitus

2021 ◽  
pp. 575-585
Author(s):  
P. Amulya Reddy ◽  
K. Saravanan ◽  
A. Madhukar
Keyword(s):  
Diabetes Mellitus ◽  
Diabetes Management ◽  
Study Data ◽  
Categorical Variables ◽  
P Value ◽  
Diabetic Patients ◽  
Physical Endurance ◽  
Glucose Levels ◽  
Patients With Diabetes ◽  
History Of

Aim: The aim of the study was to evaluate the QOL of patients with Diabetes Mellitus. Study Design: This was a prospective, observational study. Duration of Study: The study was conducted from August 2019 to January 2021 in Yashoda Hospital, Hyderabad. Methodology: Patients of either sex with ≥1year history of diabetes willing to give the consent were included in the study. Patients of either sex with <1year history of DM, Pregnant/lactating women and patients not willing to give the consent were excluded from the study. Data on Blood glucose levels (FBS, PPBS) and HbA1C was also obtained and assessed. QOLID questionnaire was administered to the patients and assessed which consisted of a set of 34 items representing 8 domains such as Role limitation due to the physical health, Physical endurance, General health, Treatment satisfaction, Symptom botherness, Financial worries, Mental health, and Diet satisfaction). Results: A total of 200 patients were analysed in the study,108(54%) were males and 92(46%) were females. The average age of the patients was 58.5 years with majority being 51-70years (73.5%) of age. Patients with higher age and females had poor QOL compared to others. The correlation between various categorical variables with that of scores of QOL in various domains was assessed, Age of the patients influenced QOL score in various domains like RLPH (p value-0.038), PE (p value-0.0183), and SB (p value-0.0002), Gender has influenced QOL score in domains like RLPH (p value-0.0008), PE (p value-0.0106), TS (p value-0.0005) and Educational Qualification has influenced QOL score in RLPH (p value-0.0008), GH (p value-<0.0001), TS (p value-<0.0001), E/MH (p value-<0.0001). Conclusion: The results concluded that overall QOL was noticeably low in Diabetic patients especially in Women and elderly thus indicating that Diabetes management is not restricted to treatment but also requires attention on QOL of patients.

scholarly journals Hypoglycemia Prevention Practice and Associated Factors Among Patients with Diabetes Mellitus Following at Public Hospitals of Central Zone, Tigray, Ethiopia, 2018

2019 ◽  
Author(s):  
Gebrewahd Bezabh Gebremichael ◽  
Teklewoini Mariye Zemichael
Keyword(s):  
Diabetes Mellitus ◽  
Associated Factors ◽  
Central Zone ◽  
Public Hospitals ◽  
P Value ◽  
Diabetic Patients ◽  
Binary Logistic Regression Model ◽  
Cross Sectional ◽  
Patients With Diabetes ◽  
At Home

Abstract Background Hypoglycemia is an acute medical situation that occurs when blood sugar falls below the recommended level. Even though, hypoglycemia prevention practice in the management of diabetes mellitus is one cornerstone in controlling the effect of hypoglycemia, hypoglycemia prevention practice among patients with diabetes mellitus is insufficiently studied. Moreover, the existed scarce literature in Ethiopia revealed hypoglycemia prevention practice is inadequate. Thus, this study tried to assess hypoglycemia prevention practices and associated factors among diabetic patients. Methods Hospital-based, cross-sectional study design was employed from April one to March one 2018 in Central Zone of Tigray Regional state of Ethiopia. A total of 272 diabetes mellitus patients were selected by systematic random sampling method from study area. The collected data was checked for its completeness and then entered into Epi data version 3.1 then cleaned and analyzed using SPSS version 23. Binary logistic regression model (AOR, 95% CI and p-value < 0.05) was used to determine the predictors of hypoglycemia prevention practice. Results the mean age of respondents was 52.19 years and about 100 (63.2%) had good hypoglycemia prevention practice. Knowledge regarding hypoglycemia [AOR = 10.34; 95% CI [5.41, 19.89]], having a glucometer at home [AOR=3. 02; 95% CI [1.12, 8.12]], attitude regarding diabetes mellitus [AOR = 2.36 CI [1.26, 4.39]], being governmental employee [AOR=5. 19, 95% CI [1.63, 16.58]] and being divorced [AOR = 0.13, 95% CI [0.32, 0.53]] were found significantly associated with good hypoglycemia prevention practice. Conclusion Around two third of the study participants were found to have good hypoglycemia prevention practice. Good knowledge and favorable attitude toward diabetes mellitus, having glucometer at home, being governmental employee and divorced were found to be the predictors of good hypoglycemia prevention practice.

scholarly journals A study to assess the correlation between HbA1c and microalbuminuria among diabetics

2020 ◽  
Vol 8 (1) ◽  
pp. 16
Author(s):  
Sruthi Kare ◽  
Vishwanath N. Reddy ◽  
Thejdeep Mahamkali
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Socioeconomic Development ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Medical College ◽  
Significant Linear Correlation ◽  
Patients With Diabetes

Background: India is one of the epicentres of the global diabetes mellitus pandemic. Rapid socioeconomic development and demographic changes, along with increased susceptibility for Indian individuals, have led to the explosive increase in the prevalence of diabetes mellitus in India over the past four decades. Diabetic Nephropathy is a common consequence of long-standing diabetes mellitus. The development of diabetic nephropathy has a dramatic increase on the morbidity and mortality of patients with diabetes. Objective of this study was to evaluate the prevalence of microalbuminuria in patients with diabetes mellitus patients.  Methods: This cross-sectional study was conducted on T 2 diabetes mellitus patients visiting medicine OPD of R L Jalappa hospital constituent hospital of Sri Deveraj Urs Medical College, Tamaka, Kolar from May 2016 to July 2016. A total of 60 type-2 diabetes patients were enrolled in the study.Results: Average duration of diabetes among study group was 8 years and most of the patients were between 6-10 years. In type 2DM patients, microalbuminuria and glycemic control have shown a significant linear correlation with duration of diabetes (p<0.05). Also, micro albuminuria has a significant correlation with increase in level of glycosylated haemoglobin.  Conclusions: The prevalence of microalbuminuria in diabetic patients was found to be high and being a developing country; there is a dire need that microalbuminuria and HbA1c testing should be done in both, newly diagnosed as well as already diagnosed type 2DM patients as an early marker of renal risk factor.

scholarly journals Analysis of COVID-19 Prevention Behaviour among Diabetes Mellitus Comorbidity Patients in Palembang

2021 ◽  
Vol 9 (2) ◽  
pp. 168
Author(s):  
Giszka Putri ◽  
Hamzah Hasyim ◽  
Nur Alam Fajar
Keyword(s):  
Diabetes Mellitus ◽  
Community Health ◽  
Statistical Significance ◽  
Health Centre ◽  
P Value ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Community Health Centres ◽  
Health Centres ◽  
Preventive Behaviour

Background: COVID-19 in Diabetes Mellitus (DM) patients are at higher risk for severe complications than people without DM. Preventive behaviour is the best way to avoid COVID-19 infection for DM patients due to its bad impact, such as severe symptoms requiring intensive care, leading to death. Objective: This study aims to analyse the COVID-19 preventive behaviour among DM comorbidity patients in Palembang. Method: The cross-sectional study was conducted from April 2021 to May 2021 using a questionnaire to diabetic patients at six community health centres in Palembang. The questionnaire has four sections: patient characteristics, knowledge, attitude, and COVID-19 prevention behaviour. A proportional random sampling technique was used to determine the number of samples according to the data on diabetic patients in each health centre. The total sample was 183 respondents from 1.266 total population diabetic patients in six community health centres. Respondents were diabetic patients aged ³ 18 years old and willing to fill out the questionnaire. Univariate, bivariate, and multivariate statistical analyses were used to analyse the data. Results: More respondents have good knowledge (50.3%), negative attitude (57.3%), and poor COVID-19 preventive behaviour (53.0%). The findings revealed a statistical significance between knowledge (P-value = 0.0001), attitude (P-value = 0.0001), and educational status (P-value = 0.0001) with COVID-19 preventive behaviour. Furthermore, knowledge is the most determinant factor of COVID-19 preventive behaviour (PR= 7.597, 95% CI: 3.701 – 15.597). Conclusion: According to this study, diabetic patients with poor knowledge are at greater risk of having poor COVID-19 prevention behaviours. COVID-19 prevention programs, especially health education programs at the community health centre, need to be improved to ensure that diabetic patients adopt reasonable and appropriate COVID-19 prevention practices.

scholarly journals A community based study on perceived knowledge of diabetes on cause, control, prevention and complications among diabetic patients in Bengaluru city

2017 ◽  
Vol 4 (9) ◽  
pp. 3416
Author(s):  
Shwetha . ◽  
K. N. Prasad
Keyword(s):  
Diabetes Mellitus ◽  
Family History ◽  
Warning Signs ◽  
Diabetic Patients ◽  
Perceived Knowledge ◽  
Community Based ◽  
Cross Sectional ◽  
Family History Of Diabetes ◽  
Duration Of Diabetes ◽  
Intervention Measures

Background: The numbers of diabetes mellitus cases are increasing among all sections of Indian population. The knowledge about the disease, associated complications and co-morbidities are not satisfactory among the public including diabetic patients. The objective of the study was to assess the perceived knowledge and determining factors on onset, control, prevention and complications of diabetes mellitus in urban area of Bengaluru.Methods: A cross sectional, descriptive and community based study with a sample size 770 randomly selected known diabetics was conducted during May to July 2016 in Bengaluru city by direct interviewing them at their doorsteps using pretested questionnaire. The data contained information about the socio-demographic profile, knowledge about the warning signs, complications, controllability, consequences and co morbidities. Data was analysed in SPSS version 18.Results: There were 43.7% and 57.5% of males and females respectively. Seventy percent of females were homemakers and two third were literates. The maximum numbers of subjects were in the age group of 41-60 years with mean age of 56±11.6 years.  Family history of diabetes was present among 40%. The median duration of diabetes was 48 months (range 1 to 360) and 38% of the subjects had co morbid conditions related to cardiovascular diseases and other systems. The perceived knowledge related to prevention, complications, consequences and controllability of diabetes was not adequate in relation to their literacy status, family history and duration of diabetes. The overall perceived knowledge was better among females than male subjects.Conclusions: The perceived knowledge about the different aspects of diabetes care at the personal level of diabetics were inadequate and needs periodic counselling as intervention measures. 

scholarly journals Use of malondialdehyde (MDA) as a screening tool for vestibulopathy inType2 diabetes mellitus

Biomedicine ◽  
2021 ◽  
Vol 41 (3) ◽  
pp. 576-579
Author(s):  
K. Sumathi ◽  
Gayathri Dilliraj ◽  
Sridevi Chaganti ◽  
Shenbaga Lalitha
Keyword(s):  
Diabetes Mellitus ◽  
Unsaturated Fatty Acids ◽  
Metabolic Diseases ◽  
Vestibular Function ◽  
Thiobarbituric Acid ◽  
Dependent Diabetes Mellitus ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Increased Risk

Introduction and Aim:Diabetes mellitus, especially type II DM is one among the most prevalent metabolic diseases in the global scale. One of the commonest complications of diabetes mellitus is vestibulopathy affecting the inner ear. Malondialdehyde (MDA) obtained from lipid peroxidation of poly unsaturated fatty acids (PUFA) is an important compound that generally serves as one of the key markers for oxidative stress. The aim of the study is to prove the significance of MDA in Vestibulopathy in Type-2 i.e.,non-insulin dependent diabetes mellitus.   Methodology: A cross-sectional study of 100 diabetic patients of age group between 35 years and 50 years were tested for vestibular function by electronystagmography(Commonly used test to determine and evaluate vestibular system). Based on the biothermal caloric stimulation the Clausen butterfly chart was generated and thus the code is ascertained. Serum levels of Malon-di-aldehyde were assayed by TBARS method (Thiobarbituric acid Reactive substances).   Results: The study proved, that there was a 4 times increased risk of developing vestibulopathy with increasing duration of diabetes. It also proved that there was an increased risk of developing vestibulopathy in diabetic patients, having MDA > 2?mol/L.   Conclusion: Thereby the study confirmed the clinical significance of periodic screening of MDA levels, in diabetic patients, particularly those with uncontrolled/poor glycemic control & with longer duration of diabetes. Estimation of their serum MDAlevels and vestibular function by the electronystagmography test, is advised in order to prevent the occurrence of diabetic vestibulopathy at the earliest and also to prevent the worsening of any such, other complications associated with the disease.  

scholarly journals Hypertension and Diabetes as a risk factor for dementia: a cross sectional study

2019 ◽  
Vol 7 (9) ◽  
pp. 3337
Author(s):  
Arshad Yahya ◽  
Robina Shamim ◽  
Kuljeet S. Anand
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Vascular Dementia ◽  
Statistical Tests ◽  
Positive Association ◽  
Cross Sectional Study ◽  
World Health ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional

Background: A relation between possible cardiovascular risk factors (hypertension and diabetes) and dementia has been studied in the past and an association has been documented, in spite of some studies pointing to the contrary. Our purpose is to analyze the relation between these risk factors and dementia and add some information to the existing concept and will try to conceptualize the pathogenesis of dementia.Methods: This was a cross sectional study. Patients were recruited from amongst those presenting to our department by convenient consecutive sampling method after taking consent. Five hundred patients of different types of dementia were enrolled. Hypertension was diagnosed using JNC7 criteria. World health organization (WHO) diagnostic criteria were used to diagnose diabetes mellitus. The open Epi software version 3 was used to find the absolute values after preparing 2×2 table. Continuous quantitative data were analyzed using chi square test. Odds ratio and Risk ratio were also calculated. For all statistical tests, a p Value less than 0.05 was taken to indicate significance.Results: Study provides the strong positive association of hypertension (HTN) and diabetes mellitus (DM) with vascular dementia (VaD) but the relationship of these risk factors were not positively correlated with other dementia. Conclusions: Positive association of these risk factors with vascular dementia were found but not with the other types of dementia.

scholarly journals Correlation of estimated glomerular filtration rate with ejection fraction among type 2 diabetes mellitus patients: results of a cross sectional study from Southern India

2020 ◽  
Vol 7 (4) ◽  
pp. 554
Author(s):  
Ali Akbar P. ◽  
Santosh R. Goudar ◽  
Prabha Adhikari ◽  
Ibrahim Masoodi ◽  
Sydney Dsouza
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ejection Fraction ◽  
Serum Creatinine ◽  
P Value ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
The Mean

Background: There is paucity of data regarding the relationship between the severity of left ventricular dysfunction and renal function impairment in diabetic patients. Aims and objectives was to study the relation between eGFR and ejection fraction in type 2 diabetes mellitus of more than 5 years duration.Methods: This cross sectional was carried out from May 2017 to May 2018 at Yenepoya Medical college a tertiary care center in the southern Indian state of Karnataka. The data on 220 diabetic patients were studied. A detailed clinical history physical examination was carried out on the study population as per the approved proforma. Apart from base line investigations, eGFR was calculated using serum creatinine levels. 2D echocardiography was done for the assessment of ventricular function.Results: Out of 220 patients, 138 were men (63%) and 82 were women (37%) and the mean age of the patients was 59.60±11.145 years. The mean duration of diabetes was 10.08±5.28 years. We found a progressive reduction in ejection fraction from 57.74±9.97% to 50.64±14.7 as the eGFR declined from <90 mL/min/1.73m2 to 30 mL/min/1.73m2. There was significant correlation between eGFR and RWMA (p value 0.001) and LVDD (p value 0.029) in this study cohort. Micro/macroalbuminuria was found to be in 55% of patients. Proteinuria had significant correlation with longer duration of diabetes, blood urea, serum creatinine and eGFR.Conclusions: This study found positive clinical correlation between LVEF and eGFR. However, it did not reach significant levels statistically. Further studies may be carried out to confirm the association.

An assessment of depression in type-II diabetics presenting at tertiary care hospital

2021 ◽  
Vol 15 (8) ◽  
pp. 2093-2095
Author(s):  
Mahwish Adnan ◽  
Ghulam Hassan ◽  
Muhammad Abdul Raziq
Keyword(s):  
Diabetes Mellitus ◽  
Behavioral Science ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Type Ii ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Type Ii Diabetics

Objective: To assess the frequency of depression in type-II diabetics presenting at tertiary care hospital. Materials & Methods: This cross sectional study was conducted at Department of Psychiatry & Behavioral Science, Sheikh Zayed Hospital, Rahim Yar Khan from April 2020 to October 2020 over the period of 6 months. Total 200 type-II diabetics having age 20-65 years either male or female were selected for this study. Depression was assessed in selected by using DSM-IV criteria for Depression. Results: Mean age was 54.37 ± 5.88 years. Out of 200 patients of diabetes, depression was noted in 46 (23%) patients. Most (98,49%) of the patients were between 51-65 years but difference of depression with age group was not statistically significant with p value 0.8958. Total 19 (20.88%) male patients and 27 (24.77%) female patients were found with depression. But depression was insignificantly associated with gender with p value 0.6315. Total 11 (14.29%) patients found with depression having duration of diabetes mellitus ≤3 years and 35 (28.46%) patients found with depression having duration of diabetes mellitus >3 years. Depression was significantly associated with duration of diabetes mellitus with p value 0.032. Conclusion: Our study concluded that prevalence of depression in type 2 diabetes mellitus patients was much higher and have shown positive association with extremes of ages and duration of disease. Keywords: Diabetes mellitus, depression, socioeconomic status, physical recovery

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