IMPACT OF BIOLOGICALLY ACTIVE SUBSTANCES ON THE UTERUS INVOLUTION AND DATE OF THE FIRST SEXUAL HUNTING AFTER CALVING

2020 ◽  
Vol 11 (2) ◽  
pp. 65-72
Author(s):  
M. V. Seba ◽  
M. I. Yagofarov ◽  
D. K. Nosevich ◽  
V. G. Kaplunenko

The aim of the researches was to improve the reproductive capacity of cows by accelerating the uterus involution after the use of a complex substances mixture of neurotropic-metabolic action (L-arganine (C6H14N4O2), sodium succinate (Na2C4H4O4), sodium glutamate (C5H8NNaO4)) and trace elements nanocarboxylates (Fe, Ca, Mn, Cu, Zn)) in the first decade of the postpartum period. The experiment was conducted on cows of the Ukrainian black-spotted dairy breed. One control and three experimental groups were formed, 10 animals in each group. Animals of the first experimental group were injected into the caudal fold in a volume of 10 ml once a day for 6 days from the fifth day after calving, the total volume of the drug was 60 ml. Animals of the second experimental group were injected the drug in a volume of 20 ml once a day for 3 days on the fifth, seventh and ninth days after calving, the total volume of the drug was 60 ml. Animals of the third experimental group were injected the drug in a volume of 20 ml once a day for three days on the seventh, eighth and ninth days after calving, the total volume of the drug was 60 ml. Animals in the control group were not injected the drug. It was found that the use of a complex substances mixture of neurotropic-metabolic compounds with nanocarboxylates of trace elements has a positive effect on the timing of uterine involution in cows and their first arrival in sexual hunting after calving. Thus, the injection of the complex according to the scheme of the second group reduces the involution of the uterus by 2.3 days (P - 0.01) and reduces the independence period by 3.4 days (P - 0.05). Injection according to the scheme of the third experimental group accelerates the involution of the uterus by 2.1 days (P - 0.05) and reduces by 2.5 days (P - 0.05) the period from calving to the onset of the first sexual hunt. The scheme in which animals were injected within six days after calving (the first experimental group) in a volume of 10 ml from the fifth day was less effective and more time consuming.

2016 ◽  
Vol 18 (2(66)) ◽  
pp. 44-48
Author(s):  
V. Gryban ◽  
D. Mylostiva ◽  
E. Pecheniy

The article presents research data on the impact of deficient dietary microelements (cobalt and selenium) and biologically active supplement Humilid  on the indicators of the reproductive function of heifers after the first calving. We have found out that Humilid and trace elements influence on the physiological state of reproductive organs and stimulate the sexual heat of animals. Regarding the duration of the period from calving to fertilized insemination, the difference between the control and experimental groups is more visible. Thus, the service period in the experimental group I (under the influence of Humilid) was 293.2 days, which is 2.6 days less than in the control group. In the experimental group II (under the influence of cobalt and selenium), it was, respectively, by 3.9 days less than in the control one. This may indicate that the minerals and dietary supplements contribute to more rapid recovery of the ovarian cycle. Protein composition of blood serum was investigated in the study of the biochemical spectrum of blood. Balancing the nutrition of animals with deficient dietary microelements and adding Humilid increase the concentration of protein molecules, which is visible from the indicator of crude protein and its components - albumen and globulin.In comparison with animals in the control group, a total protein level of heifers in the experimental group I was higher by 8.8% (P <0.05), and in the experimental group II - by 8.6% (P <0.05). This may indicate the increased intensity of synthetic and redox processes in heifers’ bodies in preovulatory period which serve best for the insemination.The level of albumen was also higher by 8.0 and 7.3% respectively under the influence of Humilid and trace elements in relation to the control group, indicating the improvement of transport of substances, in our case estradiol.As far as globulin is concerned, the growth of this class of proteins was marked by 9.4 and 9.6%, indicating the improvement of the level of resistance of the organism. Thus, the increase in blood biochemical parameters creates certain conditions in heifers’ body to improve their insemination.


Author(s):  
L. Yarmots ◽  
G. Yarmots ◽  
A. Belenkaya ◽  
M. Smyshlyaeva

Numerous studies have shown that sapropel is an effective source of macro-and microelements, as well as biologically active substances. There are about 3 million lakes on the territory of Russia, where sapropel reserves are estimated at 250 billion tons. There are 497 lakes on the territory of the Tyumen region, the estimated reserves of sapropel in them are 1398,7 million tons. The Tyumen region is a biogeochemical province for all normalized trace elements. Biologically active compounds obtained from natural raw materials, including normalized trace elements in organic form are the most promising and safe. Under the inviroments of the Tyumen region, such natural raw materials can be sapropels. The study of the effectiveness of the use of sapropels and their influence on the metabolism and milk productivity of cattle is an urgent topic. The purpose of the research was to study the influence of sapropel lake Nepryak on milk productivity indicators and the biochemical composition of the blood of cows. For the experiment 3 groups of cows have been formed (a control group and two experimental ones) based on the principle of pairs of analogs. Cows of the 1st experimental group have been got in the ration of 300 g of sapropel per head/day, 2nd experimental – 500 g/head/day. Cows of the control group did not receive sapropel in the ration. It has been found as the result of research that the use of sapropel lake Nepryak in feeding of cows in doses of 300 and 500 g/head/day had the positive influence on their milk productivity. At the same time, it is most effective to feed sapropel at the dose of 300 g/ head/day.


Author(s):  
A. Y. Karunskiy ◽  
I. V. Nikolenko

This article presents the results of the effective use of biologically active substance that belongs to hydrolyse class “Lysozyme G3” in the composition of pigs premix. New premix that can balance the main grains in pigs feeding has been developed. The main grains are wheat, corn, barley. These compounds are included into pigs feeding ration and they are the main crops in the South of Ukraine. The effect of using this new premix that contains the enzyme preparation “Lysozyme G3” for fattening pigs was also investigated. The productive effect of enzyme preparation in the rations with the same nutritional value for fattening pigs and its effect on the nutrients digestibility were studied. Experimental research activities were conducted at the agricultural enterprise “Avangard-D” LLC, Ovidiopol District, Odessa Oblast. The changes in live weight, as well as gains of fattening pigs at the age of 4, 5, 6 and 7 months were studied in the scientific and economical experience. During the main period (120 days), the increase in pigs live weight was observed in all groups. Thus, in the control group, this indicator changed from 27.8 to 107 kg; in II experimental group – from 28.1 to 109.2; in III experimental group – from 28.0 to 111.7 kg. When removing animals from fattening, the difference in live weight between the III experimental and control groups was 4.4% and it was statistically significant (P > 0.95). The average daily gains in piglets of II and III experimental groups significantly exceeded the indices of control one by 2.4% and 5.7%, respectively. The nutrients digestibility in animals of all experimental groups was studied to analyze more carefully. The analysis of digestibility indices in pigs rations during experiment (when pigs are fed with premix that contains biologically active substance Lysozyme G3), and its content in the ration indicated that nutrient digestibility indices had changed into the direction of increase. Feed consumption was calculated after analyzing these indices. Thus, the smallest feed consumption per unit of live weight gain was established in the third experimental group, where it was 3.2 feed units and was less in comparison with animals of the control group by 3.4%. During scientific and economical researches, blood samples were taken from animals of the first control group and the third experimental one for morphological and biochemical studies. It was found that the blood parameters of experimental animals during the entire period of fattening were within the physiological norm. The amount of protein in the blood indicates that animals of experimental group have higher growth rate by 10.9%. The economic indicators directly reflected above mentioned facts when the calculation of the economic part of the research were carried out. Thus, we got 1870.5 UAH from the first group, 1934.3 UAH from the second group, 1989.4 UAH from the third group, selling products from one head. Accordingly, the level of profitability of pork production was: in the first group (control) – 13.5; in the second (1 kg/ton of premix) – 16.5%; in the third (2 kg/ton of premix) – 19.8%.


2021 ◽  
Vol 22 (5) ◽  
pp. 745-753
Author(s):  
N. A. Shemuranova ◽  
N. A. Garifullina

The experiment was conducted on the basis of the agricultural production cooperative kolkhoz "Iskra" (Kirov region) in 40 highly productive cows of black-motley Holstein zed breed, which were divided by the method of paired analogues into 4 groups of 10 heads. The influence of the biologically active additive Lamarin Saldonum on the reproductive function and the milk productivity of cows was studied. The animals of the experimental groups were given the additive daily in doses of 0.1, 0.2 and 0.3 g per 1 kg of live weight for 30 days before calving during 60 days. It has been established that Lamarin Saldonum does not negatively affect the duration of pregnancy, while it helps to reduce the number of generic and postpartum diseases. In cows of the experimental groups retention of placenta was registered 10-20 % less often and the development of postpartum endometritis was observed 10-30 % less often. It was also found that in the animals of the experimental groups the indifferent period was reduced by 8.13-14.49 %, the number of days from calving to fruitful insemination was decreased by 30.51-53.82 days, the number of days of infertility was reduced by 33.63-59.37 % compared to intact animals. The cows of the second experimental group showed the best milk productivity, where the gross milk yield exceeded the values of the control group in the first month of lactation by 19.63 %, in the second - by 13.43 %, in the third - by 39.87 %. The need for additional studies to determine the effective dose of the additive Lamarin Saldonum, which will have a stimulating effect on the reproductive function of high-productive cows, has been established.


2020 ◽  
Vol 22 (100) ◽  
pp. 23-27
Author(s):  
D. V. Kytaieva ◽  
R. V. Petrov

The specific microclimate of poultry premises contributes to the accumulation of microflora, which may contain pathogenic and opportunistic microorganisms. The concentration of microorganisms in poultry houses increases over time and reduces the resistance of the bird. Researchers have reported very high growth rates of mesophilic aerobic microorganisms, which include most pathogenic bacteria, namely: gram-positive cocci (staphylococci, enterococci) and gram-negative bacteria of the family Enterobacteriaceae (Escherichia coli, Salmonella spp., Salmonella spp.). Proteus spp., Klebsiella spp., and Pseudomonas spp. The goal of our research was to investigate and compare the effectiveness of two probiotics for turkeys, one of which contains recombinant strains of lactic acid microorganisms of intestinal intestinal symbionts, and the other based on a mixture of biologically active substances based on natural components of organo-mineral origin. The task of our work: 1. To study the microflora of the gastrointestinal tract during the use of probiotics after the use of antiparasitic drugs in nematode invasion of turkeys. 2. Compare the growth of young animals with the use of probiotics and provide suggestions on the prospects for the most effective use of probiotics in the cultivation of turkeys. 3. Investigate changes in the physicochemical properties of turkey meat when using probiotics and compare them with controls. To conduct the experiment, three experimental groups of turkeys cross Hybrid converter, 14 days old, each with 10 heads. The first and second experimental groups were given an antiparasitic drug containing levamisole hydrochloride at a dose of 5 ml per 5 liters of water once. After that, probiotics were used for each experimental group of birds. Two types of probiotics were used in the experiments: the first contains recombinant strains of lactic acid microorganisms of intestinal intestinal symbionts: Bifidobacterium bifidum, Bacillus thermophilus, Bacillus coagulance, Bacillus subtilis. Has antimicrobial, antiviral and antioxidant activity; the second preparation contains a mixture of biologically active substances, based on natural ingredients of organo-mineral origin, which includes organic substances – fulvic and humic acids. The third group (control) used only the above antiparasitic drug. After the experiment, at the age of 78 days, poultry was slaughtered and studies of the effect of probiotics on weight, physicochemical parameters of meat. When testing turkeys for helminths. As a result of research, helminths were identified, which were attributed to the causative agent of heterakidosis - Heeterakis gallibarum. After that, it was decided to carry out deworming with levamisole hydrochloride. After a course of treatment, it was found that no deaths were observed in the first experimental group; in the second experimental group, one head died, and in the third control group, which did not use probiotics, the death was two heads. The use of probiotics due to competition reduces the level of total bacterial contamination and coliform bacteria in the experimental groups. And the level of lactic acid bacteria in the experimental groups was higher than in the control. The use of probiotics had a positive effect on weight gain of experimental turkeys, compared with the control group, where probiotics were not used. The difference in the first experimental group compared with the control averaged 618 g, and in the second group – 198 g. Post-mortem examination of turkey carcasses showed that the indicators of the experimental and control groups differ. In terms of external organoleptic characteristics, the meat obtained from the slaughter of experimental birds does not differ from the meat of poultry in the control group. Conclusions and prospects for further research. The use of probiotics based on lactic acid bacteria proved to be the most effective and ensured the complete preservation of livestock. Due to competition, it reduced the level of coliform bacteria by an average of 6.67 % in the experimental groups; the level of lactic acid bacteria in the experimental groups was 4.89 % higher than in the control. The use of probiotics increased the weight gain of poultry by 3.28 %. No significant effect on the organoleptic and physicochemical properties of meat was observed.In the future it is planned to study the microflora of turkey slaughter products.


Author(s):  
Meryanti Napitupulu And Anni Holila Pulungan

This study was conducted as an attempt to discover the effect of applying Demonstration Method on students’ achievement in speaking skill. It was an experimental research. The subject was students of Grade XII, Vocational High School (Sekolah Menengah Kejuruan: SMK), which consisted of 79 students. The research was divided into two groups: experimental and control groups. The instrument used to collect the data was speaking test. To obtain the reliability of the test, the writer applied Kuder Richardson 21 formula. The result of the reliability was 0.7, and it was found that the test was reliable. The data were analyzed by using t-test formula. The analysis showed that the scores of the students in the experimental group were significantly higher than the scores of the students in the control group at the level of significant m = 0.05 with the degree of freedom (df) 77, t-observed value 8.9 > t-table value 1.99. The findings indicate that using Demonstration Method significantly affected the students’ achievement in speaking skill. So, English teachers are suggested to use Demonstration Method in order to improve students’ achievement in speaking skill.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Mingchen Zou ◽  
Haotian Wu ◽  
Shuangquan Yao ◽  
Dong Ren ◽  
Song Liu ◽  
...  

Abstract Background This study was done to observe the incidence of Osteo-line on the femur neck and to explore the clinical application of Osteo-line in osteotomy. Methods Eighty-nine adult femur specimens were selected to observe the incidence of Osteo-line on the femur neck. From August 2015 to January 2019, a total of 278 patients who completed unilateral hip arthroplasty at the Third Hospital of Hebei Medical University were retrospectively included. Patients who accepted osteotomy via Osteo-line on the femur neck were defined as the experimental group (n = 139), and patients who accepted osteotomy via traditional method (The femoral distance 1.5 cm above the trochanter was retained for osteotomy by visual inspection.) were defined as the control group (n = 139). According to the postoperative pelvic X-ray, Photoshop was used to evaluate the leg length discrepancy (LLD) by the CFR-T-LT method. Results Among the 89 specimens, the incidence of anterior Osteo-line was 75.28%, and the incidence of posterior Osteo-line was 100%. According to the clinical application results, the incidence of anterior Osteo-line on the femur neck was 80%, and the incidence of posterior Osteo-line was 100%. The Osteo-line was clearer than those on the femoral specimens. Twenty-six cases had LLD greater than 1 cm (9.29%), including 2 cases in the experimental group and 24 cases in the control group. The average postoperative LLD in the experimental group (0.19 ± 0.38 mm) was significantly shorter than in the control group (0.54 ± 0.51 mm)(P = 0.005). Conclusion The incidence of Osteo-line on the femur neck was high, and patients who accepted osteotomy via Osteo-line on the femur neck can achieve shorter postoperative LLD than the control group.


2020 ◽  
Vol 5 (2) ◽  
pp. 63-71
Author(s):  
Vladimir Nikulin ◽  
Aleksandra Mustafina

The aim of the study is to increase the productive qualities of broiler chickens by including ultrafine silicon oxide into main diet. During the experiment, the biological effect of ultrafine silicon oxide on broiler chickens was estab-lished. Use of ultrafine SiO2 particles for poultry feeding contributed to an increase in the number of red blood cells and content of total protein and albumins. By the end of the experiment, the number of red blood cells in birds in-creased by 17.43% (P≤0.001) – in the blood of birds of the first experimental group, 16.51% (P≤0.01) – the second one, 20.80% (P≤0.001) – the third experimental and 21.71% (P≤0.001) – the fourth experimental group, compared with the indicator of the control group. The amount of total protein in blood serum of chickens of the first and the second experimental groups increased by 1.36-1.39 %, in the third and fourth ones there was a significant (P≤0.05) increase by 5.45 and 3.05%, respectively. The blood glucose content of chickens in the experimental groups is higher by 8.04-23.65% compared to this indicator with ones in the control group. During the experiment feed con-sumption per 1 kg gain of live weight decreased: in the first experimental group by 3.00 % in the second by – 0.50 %, the third – 6.00 % the fourth– by 4.50 %, compared to this with the control group. The chicken’s vibrancy of the first the experimental group was higher by 4.77 %, the second – by 6.20 %, the third – by 19.25 % and the fourth– by 11.59% than in the control one. Consequently, when converting the feed energy into the body energy of a broiler chicken, the energy conversion coefficient of the experimental group of poultry is higher than that of the control one by 7.16-21.76 %. Thus, the most optimal dose for further research was determined.


Author(s):  
K. I. Khidirov ◽  
◽  
G. J. Kutlieva ◽  
B. I. Turaeva ◽  
N. A. Elova ◽  
...  

Research has been carried out to study the influence of "ProBioKorm Uz", a biologically active feed additive, on the development and physiological characteristics of rabbits of ‘New Zealand’ breed. During the experiment, 2 experimental and a control groups were formed. Adding "ProBioKorm Uz" to the main feed at the rate of 1% and 2% had an increase in experimental group rabbits’ live weight. Average live weight of them was higher by 5,7 %-3.8% than in the control group. Feed units composed 1.59%, dry matter 0.56 kg (3.61%) and crude protein 0.11 kg (3.59%) compared with the control group. Rabbits of experimental groups had higher indicators of erythrocytes concentration by 0.34-1.00 1012/l (10.34-19.53%), leukocytes - by 0.370-0.46 109/l (5.66-8, 06%), as well as a high level of hemoglobin by 7.42-11.08 g/l (6.81-10.08%) and total protein - by 2.40-4.48 (3.64-6, 42%).


Author(s):  
S. A. Shpуnova ◽  
O. A. Yadrishchenskaya ◽  
T. V. Selina ◽  
E. A. Basova

In order to increase the meat productivity of broiler chickens, increase production volumes and reduce the prime-cost of poultry products, it is necessary not only to ensure balanced feeding and compliance with production technology but also to include in the poultry diet non-traditional additives, biologically active substances that contribute to the normalization of metabolic processes and improve the digestibility of feed nutrients. One of these dietary additives is Betulin extracted from birch bark, which has antioxidant and immunomodulatory properties. In this regard, the purpose of the research was to study the influence of compound feed with the introduction of 2 % feed additive based on a synthetic microspherical nanoporous carbon carrier containing biologically active Betulin in its composition on the productivity of broilers. The results of studies on broiler chickens using compound feed with 2 % feed additive have been presented in the article. It has been found that the feed consumption per 1 kg of live weight gain in poultry of the experimental group have been lower by 9,5 % due to better absorption of nutrients, the live weight of broiler chickens of the experimental group at the age of 42 days was 2625,6 g and it was higher than the control group by 3,68 %. The digestibility of crude protein and fat reached 92,73 and 88,03 %, which exceeded the control group by 1,03 and 3,03 abs.%, respectively. It has been found that the use of compound feed with 2 % of the feed additive with the biologically active substance is of practical importance in connection with the increase in the productivity of broilers and the level of profitability of meat production by 8,2 abs.%.


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