scholarly journals INTEGRAL HEMATOLOGICAL INDICES OF NON-SPECIFIC RESISTANCE OF PIGS AS A CRITERION OF THEIR PRODUCTIVE QUALITIES UNDER THE INFLUENCE OF TECHNOLOGICAL STRESS FACTORS

2021 ◽  
Vol 247 (3) ◽  
pp. 42-46
Author(s):  
N.A. Garskay ◽  
◽  
Keyword(s):  
Reference Values ◽  
Specific Resistance ◽  
Stress Factors ◽  
Primary Data ◽  
Nonspecific Resistance ◽  
Hematological Indices ◽  
Blood Indices ◽  
Direct Dependence ◽  
Productivity Indicators ◽  
Technological Stress

The research was carried out on a purebred livestock of the main sows of the Poltava meat breed. In the blood, the amount of leukocyte formula was determined and, on the basis of the primary data, integral leukocyte indices were calculated, characterizing the nonspecific resistance of the organism. Approximate reference values of blood indices were established in the population of healthy sows of the Poltava meat breed, in which technological stress led to the development of the stage of resistance. The main load under the action of technological stress in pigs is experienced by the agranulocytic link in the blood, especially monocytes. No reliable interrelationships between blood indices and productivity indicators were established, however, a direct dependence of some indices on other links of the body's resistance was revealed.

scholarly journals Dynamics of changes in clinical-hematological indices in pigs in infections pathology

2019 ◽  
pp. 16-20
Author(s):  
Лідія Коваленко ◽  
Олександр Коваленко
Keyword(s):  
Early Stage ◽  
Specific Treatment ◽  
Gastrointestinal Diseases ◽  
The Body ◽  
Stress Factors ◽  
Nonspecific Resistance ◽  
Hematological Indices ◽  
Strategic Direction ◽  
Causative Agents ◽  
Livestock Products

The article presents the results of a number of studies on the causative agents of the associated form of pig gastrointestinal diseases. At present, it is a strategic direction in addressing the issue of providing the population of various latitudes with livestock products that meets all the requirements of  EFSA. Pig production has its development and is becoming a promising industry on this issue. One of the significant veterinary dilemmas that reduce the efficiency of technological processes in breeding and raising pigs, there are still diseases of young animals associated with disruption of the gastrointestinal tract. In many countries where pig breeding is developed, this issue comes first because the manifestation of pathological processes in the body of piglets, at an early stage of their development, leads to reinvestment of a healthy livestock in this industry. Monitoring of research results over the past years, not only in our country, but also beyond its borders, shows that abiotices stress factors of the environment contribute to the reduction of nonspecific resistance of the organism of piglets. Diseases caused by pathogens of an infectious nature are closely interconnected with the body and environmental factors. Despite the fact that specific treatment methods aimed at eliminating the diarrhea syndrome of newborn piglets, the safety of the livestock remains one of the most acute problems in veterinary medicine. A lot of ascertaining data on the role of Escherichia Coli and Salmonella in infectious diseases of young animals makes it possible to develop systems of measures to combat these diseases, to widely use individual chemotherapeutic drugs, their combinations to determine effectiveness.

scholarly journals БРОНХОПНЕВМОНІЯ ТЕЛЯТ: ДІАГНОСТИКА ТА КОМПЛЕКСНА ТЕРАПІЯ

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 95-99
Author(s):  
L. Slivinska ◽  
S. Demydjuk ◽  
А. Shcherbatyy ◽  
P. Mazurok
Keyword(s):  
Positive Impact ◽  
Specific Resistance ◽  
Inorganic Phosphorus ◽  
Integrated Treatment ◽  
Nonspecific Resistance ◽  
Carotene Content ◽  
The Third ◽  
Acid Base Status ◽  
Biochemical Research ◽  
Experimental Group

The results of nonspecific resistance indices, hematological, biochemical research on complex treatment of calves suffering from bronchopneumonia. It is established that the use of antibiotics (intramitsynu, tsefatoksymu and betamoksu LA), drugs that regulate the acid–base status, provide therapeutic efficacy, respectively – 75, 94 and 88% and shorten the duration of their treatment in 7 – 12 days. The treatment had a positive impact on the overall condition of the animals. In the blood have established probable increase in the number of red blood cells, respectively, 23.2% (p ˂ 0.001); 36.6 (p ˂ 0.001); 29.5% (p ˂ 0.05), hemoglobin contents to 8.04 (p ˂ 0.05); 17.3 (p ˂ 0.001) and 17.5% (p ˂ 0.001), reducing the number of leukocytes (p ˂ 0.001) according to 31.8; 34.3; 36.6%. The content of total protein in serum of calves experimental groups increased to 3.75 (p ˂ 0,001); 6.38 (p ˂ 0.05) and 6.93% (p ˂ 0.001), respectively, due to increased albumin fraction in the second experimental group 18.4% (p ˂ 0.001), the third – 14.8% (p ˂ 0,01). The results showed that the applied treatment had a positive impact on the carotene content in blood serum (to 43.5; 34.6; 46.0%; p ˂ 0.05), total calcium (respectively 15.0, 14.7; p ˂ 0.05; 18.3%; p ˂ 0.05) and inorganic phosphorus (6.4; 15.3; 15.8%; p ˂ 0.05).Integrated treatment of calves suffering from bluetongue bronchopneumonia, helped indexes increase non–specific resistance. The data obtained by the use of antibiotics (intramitsynu, tsefatoksymu and betamoksu LA) promoted faster normalization lizotsymnoyi and bactericidal activity of blood. Thus, in the first experimental group LASK increased by 25.6% (p ˂ 0.001); the second – by 26.3% (p ˂ 0.001) and the third at 35.3% (p ˂ 0.001). BASK calves tended to increase according to 11.7; 10.6 and 11.3%. 

FACTORS OF NONSPECIFIC RESISTANCE OF CALVES IN DAIRY CATTLE BREEDING

THE BULLETIN ◽  
2021 ◽  
Vol 389 (1) ◽  
pp. 81-88
Author(s):  
V.G. Semenov ◽  
D.A. Baimukanov ◽  
A.S. Alentayev ◽  
N.K. Kirillov ◽  
A.K. Karynbayev ◽  
...  
Keyword(s):  
Blood Cells ◽  
Lysozyme Activity ◽  
Small Farm ◽  
Cattle Breeding ◽  
Nonspecific Resistance ◽  
Serum Bactericidal Activity ◽  
Dairy Cattle Breeding ◽  
Γ Globulins ◽  
Technological Stress ◽  
Observation Period

Under the influence of the biostimulant, an increase in the morphological and biochemical data of blood in calves grown both on private plots and on small and medium farms, which at the end of the observation period exceeded the control values: the number of red blood cells - by 0.98; 0.81 and 0.79x1012/l, hemoglobin - by 9.8; 7.0 and 6.2 g/l, albumins - by 2.2; 2.8 and 3.5 g/l, γ-globulins - by 5.5; 3.7 and 5.6 g/l (P <0.05-0.001), respectively. The data on the leukocyte phagocytic activity, plasma lysozyme activity, serum bactericidal activity, and immunoglobulins were higher than in the control: when rearing calves in private subsidiary plots - by 5.6%, 4.8%, 5.5% and 4.7 mg/ml, on a small farm - by 5.2; 4.2; 7.8 % and 3.6 mg/ml and on a medium farm - by 5.8%, 3.6%, 4.4% and 4.3 mg/ml, respectively (P<0.05-0.01). A rising in the technological stress on the calf’s organism was revealed depending on the increase in the enterprise capacity, which is confirmed by the bioamine blood spectrum.

scholarly journals Bioactivity Study of the C60-L-Threonine Derivative for Potential Application in Agriculture

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Gayane G. Panova ◽  
Evgeny B. Serebryakov ◽  
Konstantin N. Semenov ◽  
Nikolay A. Charykov ◽  
Olga S. Shemchuk ◽  
...  
Keyword(s):  
Biological Activity ◽  
Plant Growth ◽  
Ultraviolet Radiation ◽  
Potential Application ◽  
Antioxidant Properties ◽  
Photosynthetic Apparatus ◽  
Stress Factors ◽  
Biological Study ◽  
Nonspecific Resistance ◽  
Pesticide Load

The present paper reports data on the biological activity of nanocompositions based on a C60-L-threonine (C60-Thr) derivative. These nanocompositions promote the nonspecific resistance of plants to the action of stress factors (ultraviolet radiation, pesticides, and phytopathogens). Additionally, we determined the perspectives of the C60-Thr adduct application in the cultivation of plants due to the decrease of the pesticide load on the environment. The biological study of C60-Thr revealed the plant growth-stimulating ability due to its influence on the photosynthetic apparatus activity and antioxidant properties.

scholarly journals Effects of Glucose Control on Hematological Indices in Patients with Diabetes Mellitus

2014 ◽  
Vol 2 (1) ◽  
pp. 83-88
Author(s):  
Ceyhun Varım ◽  
Tezcan Kaya ◽  
Ahmet Nalbant ◽  
Ayşenur Uçar ◽  
Ali Tamer
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Therapy ◽  
Glucose Control ◽  
Insulin Treatment ◽  
Treatment Modalities ◽  
Hematological Indices ◽  
Blood Indices ◽  
Insulin Group ◽  
Patients With Diabetes

Aim: We aimed to investigate the effects of diabetes treatment modalities on haematological parameters and leukocyte formula in patients with type 2 diabetes mellitus.Materials and Methods: The study included 102 patients with type 2 diabetes, out of which 51 receiving insulin treatment and 51 receiving oral antidiabetics (OAD). Hemogram data of insulin and OAD treated groups were compared.Results HbA1c levels were 11.12 ± 2.09 mg/dl in insulin group and 7.94 ± 2.1 mg/dl in OAD group p=0.001. Platelet counts were 27866.67 ± 77693 109/L before treatment and 258941.18 ± 69068.2 109/L in OAD group at six months, p: 0.015 whereas; 293011.76 ± 73711.21 109/L before treatment and 289492.86 ± 82631.49 109/L in insulin group at six months p: 0.821. Monocyte counts were 0.47 ± 0.12 109/L before the treatment and 0.57 ± 0.12 109/L in mix insulin therapy subgroup at six months, p:0.004; monocyte percentage was % 6.11 ± 1.74 before the treatment and %7.51 ± 2.57 in mix insulin subgroup at six months p:0.039;  Basophiles counts were 0.1 ±  0.02 109/L before treatment and 0.09 ± 0.04 109/L in intensive insulin therapy subgroup at six months, p: 0.005; Lymphocyte and basophils counts were significantly decreased at six months insulin treatment as compared to the pretreatment values.Conclusion: This study showed that, glucose control effects; blood indices HbA1C, basophiles, eosinophils, platelets and lymphocytes counts.

scholarly journals Blood indices and circulating tumor cells for predicting metastasis of hepatocellular carcinoma after liver transplantation

2020 ◽  
Author(s):  
Li Zhuang ◽  
Xiang-yan Liu ◽  
Heng-kai Zhu ◽  
Zhuo-yi Wang ◽  
Wu Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Transplantation ◽  
Logistic Regression ◽  
Circulating Tumor Cell ◽  
Microvascular Invasion ◽  
Term Survival ◽  
Hematological Indices ◽  
Blood Indices ◽  
The Third

Abstract Background: Liver transplantation (LT) can benefit the long-term survival of hepatocellular carcinoma (HCC) patients. We hypothesized that circulating tumor cell (CTC) levels and subtypes are intimately associated with metastasis status of HCC patients, and this study was designed to test that compositive hematological indices including CTC can provide sensitive and accurate prediction of post-LT metastasis. Methods: Between 2017 and 2018, HCC patients receiving LT were included for analysis. The 24-month follow-up was mainly conducted by outpatient and telephone. Blood samples were collected, and hematological indices were examined. The outcomes such as PFS, recurrence, metastasis, location of recurrence/metastasis, and number of metastases were recorded. Results: The follow-up analysis showed that microvascular invasion (MVI) classification at the baseline is associated with metastasis. Next, AFP level was another useful indicator of postoperative metastasis, especially at the third or fourth month; the PIVKA-II level 3 months after LT was significantly higher for those who had later metastasis. The mesenchymal CTC level at the 45th day was increased for in the metastasis group. Using two-ends Logistic regression, the calculated value MP (metastasis predictor, by above factors). Had an AUC of 0.858 in the ROC curve, with a cutoff value of 0.328. In conclusion, microvascular invasion, AFP level at the third or fourth month, PIVKA-II level at the third month, and mesenchymal CTC level at day 45 were associated with post-LT metastasis. Conclusion: Using Logistic regression based on above variables, the 2-year metastasis can be predicted with satisfactory sensitivity and accuracy.

scholarly journals Prevalence of Parasitic Infections on Hematological Indices of Horses in the Gombe Royal Houses

2018 ◽  
Vol 1 (2) ◽  
pp. 144-151
Author(s):  
U.A. Turaki
Keyword(s):  
Cellular Response ◽  
Management Practice ◽  
Parasitic Infection ◽  
Parasitic Infections ◽  
Standard Laboratory ◽  
Hematological Indices ◽  
Blood Indices ◽  
Laboratory Procedures ◽  
And Performance

The prevalence and effects of parasitic infections on hematological indices of horses in royal house of Gombe was studied. A total of 150 male horses were used for the study (January to March, 2017). Blood, feces and skin scrapings were collected from each horse and examined using various standard laboratory procedures. The coprological results showed that Ascaris accounted for 10% (15), flatworms (fasciola) 4% (6) and hookworms 4.6% (7). The skin scrapings, Mange accounted for 4 (2.6%), and ticks 8 (5.3%) while hemoparasitological analysis showed that Babesia accounted for 5 (3.33%). The blood indices showed that horses infected by parasites have significantly (p<0.05) lower RBC PCV, HB, and platelets compared to non infected horses while the WBC values increased significantly (p<0.05) due to immune-cellular response to the parasitic infection. The findings showed that parasitism is a problem in the stables examined and calls for proper stable hygiene, improved management practice, regular and strategic parasite monitoring and deworming programmes in order to achieve improved health and performance.

scholarly journals Causes of Stress among Students in Higher Educational Institutions in India

2021 ◽  
Vol 4 (1) ◽  
pp. 48
Author(s):  
Pratibha Goyal ◽  
Alok Kumar Chakrawal ◽  
Richa Banerjee
Keyword(s):  
Uttar Pradesh ◽  
Work Load ◽  
Stress Factors ◽  
Primary Data ◽  
Educational Institutions ◽  
Higher Educational Institutions ◽  
Demographic Profile ◽  
Financial Difficulties ◽  
Main Factors ◽  
Higher Educational

A student has to deal with pressure from many directions. When the extent of the pressure exceeds the capacity of an individual, it becomes stressful. Students may experience stress due several factors like academics, workload, relationships with friends and peers, teachers, parents, job and career aspirations and financial problems. The present study was carried out to find the level of stress and the main factors responsible for it among students in higher educational institutions in India. From all over India, a sample of 616 students was taken. The respondents were the states of Assam, Gujarat, Punjab, Rajasthan, Uttar Pradesh, Madhya Pradesh, Bihar and Rajasthan. Primary data was collected with the help of a structured and pre-tested questionnaire. It included information about demographic profile of the respondents and had seven sub-scales pertaining to different stress factors. Results showed that moderate to low level stress was experienced by majority of the students. 'Job and career' and 'financial difficulties' were the main causes of stress. The next important factors were academics and work load. This paper further analyses the important reasons behind each stress factor.   Received: 18 November 2020 / Accepted: 26 February 2021 / Published: 17 May 2021

scholarly journals Association of haplotypes for SNPs in the LTR regions of bovine leukemia virus with hematological indices of cattle

2019 ◽  
Vol 23 (3) ◽  
pp. 262-269 ◽  
Author(s):  
N. V. Blazhko ◽  
S. Kh. Vyshegurov ◽  
A. S. Donchenko ◽  
K. S. Shatokhin ◽  
T. I. Krytsyna ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Leukemia Virus ◽  
White Blood Cells ◽  
Biological Species ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Distribution Width ◽  
Hematological Indices ◽  
Blood Indices

Molecular typing of BLV samples isolated from Holsteinized Russian Black Pied cattle was carried out, and various cytofluorometric and morphological blood indices were examined. We performed the total count of white blood cells (WBC), lymphocyte (lymf), granulocyte (gran), monocyte (mon), red blood cell (RBC), hemoglobin (HGB), hematocrit (HTC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red blood cell distribution width (RDW), platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), and platelet crit count (PCT). The LTR-region of BLV was haplotyped. Only viruses of haplotypes I (0.33±0.03) and III (0.67±0.03) of the eight possible were detected. The ratio of hematologically sick, healthy, and suspected carriers of BLV of haplotypes I and II was comparable with the results of other researchers. The numbers of leukocytes, erythrocytes and platelets in the blood of carriers of haplotype III exceeded the corresponding parameters of cattle affected by the virus of haplotype I. It is interesting to note that the difference in the hemolytic status of animals was manifested not only by the concentration of leukocytes as direct immune agents but also by the count of erythrocytes and platelets, which are not directly involved in the immune response. The number of particles of haplotype III of the BLV circulating in the blood of infected individuals exceeded that of the carriers of haplotype I. In this connection, an assumption was made about the evolutionary advantage of the more virulent haplotype III. However, the results of our own research in conjunction with the data of other scientists indicate that the high virulence of individual virus strains is a consequence of the tendency to implement the maximum possible intensity of the synthesis of virus particles but not of the high damaging effect alone. It is shown that high lethality is evolutionarily disadvantageous for viruses, since the extinction of the carrier as a biological species is fraught with the disappearance of the virus itself.

scholarly journals INFLUENCE OF IMMUNOMODULATORS ON NON-SPECIFIC RESISTANCE AND PRODUCTION OF NITRIC OXIDE (II) IN THE ORGANISM OF CALVES

2021 ◽  
Vol 247 (3) ◽  
pp. 267-272
Author(s):  
L.A. Tukhvatullina ◽  
◽  
R.G. Karimova ◽  
◽  
Keyword(s):  
Nitric Oxide ◽  
Blood Serum ◽  
Specific Resistance ◽  
Lysozyme Activity ◽  
Nonspecific Resistance ◽  
E Coli ◽  
Serum Lysozyme ◽  
High Concentrations ◽  
Nitrate And Nitrite ◽  
Stimulation Of

The article presents data on the dynamics of bactericidal activity of blood serum against St. aureus and E. coli, and the lysozyme activity of calf blood serum against Micrococcus lisodeicticus, as well as nitrate and nitrite anions when immunomodulators are administered. It has been established that administration of «Fosprenil» increases bactericidal and lysozyme activity of blood serum, whereas, Imunophane increases nonspecific resistance without affecting lysozyme activity. Nitric oxide (II) has been shown to be directly involved in the mechanism of non-specific immunity. At the same time, the stimulation of serum lysozyme activity requires nitric oxide (II) formation in high concentrations (above 50 µmol/l).

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