Morphometric analysis of the vestibular sensory epithelia of young adult rat

2003 ◽  
Vol 12 (4) ◽  
pp. 145-154
Author(s):  
R.J. Wubbels ◽  
H.A.A. de Jong ◽  
J. van Marle
Keyword(s):  
Cell Density ◽  
Hair Cells ◽  
The Elderly ◽  
Sensory Cells ◽  
Cross Sectional ◽  
Progressive Development ◽  
Adult Rat ◽  
Stage Of Development ◽  
Crista Ampullaris ◽  
Vestibular Sensory Epithelia

The appearance of vestibular sensory cells and their progressive development has been the subject of many ontogenetic studies. Because deteriorating hair cells are supposed to play a role in balance disorders of the elderly, the final stage of development (i.e. senescence) has been investigated as well. It is generally assumed that the number of hair cells in crista ampullaris, saccule and utricle slowly but steadily decreases with age. However, actual data covering the period between maturation and senescence are scarce. In the present study, rat vestibular epithelia were labeled for actin and tubulin. Morphology was inspected from immediately after weaning until the age of 12 months. Although, postnatal development was no part of this study some data on one day old epithelia are presented for comparison. At postnatal day 1, hair bundles are still shorter than in mature sensory organs, the width of the zonula adherens is less, and the apical cross-sectional area of the epithelial cells is smaller. After one month, maturation is complete. Total cell density is 400âĂŞ500 per 0.01 mm 2 , both in the otolith maculae and in the cristae ampullares. During the first year after maturation, no changes in epithelial morphology were observed and cell density remains constant.

scholarly journals Expression and Localization of BDNF/TrkB System in the Zebrafish Inner Ear

2020 ◽  
Vol 21 (16) ◽  
pp. 5787
Author(s):  
Antonino Germanà ◽  
Maria Cristina Guerrera ◽  
Rosaria Laurà ◽  
Maria Levanti ◽  
Marialuisa Aragona ◽  
...  
Keyword(s):  
Inner Ear ◽  
Hair Cells ◽  
Sensory Cells ◽  
Acoustic System ◽  
Rt Pcr ◽  
Double Immunofluorescence ◽  
Specific Receptor ◽  
Cell Localization ◽  
Age Dependent ◽  
Crista Ampullaris

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is involved in multiple and fundamental functions of the central and peripheral nervous systems including sensory organs. Despite recent advances in knowledge on the functional significance of BDNF and TrkB in the regulation of the acoustic system of mammals, the localization of BDNF/TrkB system in the inner ear of zebrafish during development, is not well known. Therefore, the goal of the present study is to analyze the age-dependent changes using RT-PCR, Western Blot and single and double immunofluorescence of the BDNF and its specific receptor in the zebrafish inner ear. The results showed the mRNA expression and the cell localization of BDNF and TrkB in the hair cells of the crista ampullaris and in the neuroepithelium of the utricle, saccule and macula lagena, analyzed at different ages. Our results demonstrate that the BDNF/TrkB system is present in the sensory cells of the inner ear, during whole life. Therefore, this system might play a key role in the development and maintenance of the hair cells in adults, suggesting that the zebrafish inner ear represents an interesting model to study the involvement of the neurotrophins in the biology of sensory cells

scholarly journals RELATIONSHIP OF ELDERLY KNOWLEDGE LEVEL WITH PARTICIPATION IN IMPLEMENTATIONGYMNASTIC IN THE CITY OF SEMARANG

2019 ◽  
Vol 8 (2) ◽  
pp. 115
Author(s):  
Dewi Elliana
Keyword(s):  
Human Life ◽  
Sampling Technique ◽  
The Elderly ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Stage Of Development ◽  
Chi Square Test ◽  
Level Of Knowledge ◽  
Relationship Of

Old age is said to be the final stage of development in human life. Efforts to support the achievement of life expectancy begin with improving services in the field of health in the elderly. In Indonesia in 2010 there were 23,992,513 elderly people. The purpose of this study was to determine the relationship of the level of knowledge of the elderly about elderly gymnastics with participation in the implementation of elderly gymnastics in Pudakpayung Village, Banyu Manik District, Semarang City. This study used a cross sectional design and included the type of correlation. In this study the sampling technique used purposive sampling with as many as 80 respondents. The data is then analyzed using Chi Square Test. This research was conducted in May 2014. The results of the study showed that the level of knowledge of the elderly about elderly gymnastics was mostly included in the category of 37 (46.3%) respondents. While the participation in the exercise of elderly gymnastics, mostly including the category did not follow as many as 39 (48.8%) respondents. The conclusion of this study is that there is a relationship. The value of the level of knowledge of the elderly about elderly gymnastics with participation in the implementation of elderly gymnastics with a p value of 0,000. The value of p value is smaller than 0.05 (0,000 <0,05). Suggestions given to the community, especially the elderly, increase their knowledge about the benefits of elderly gymnastics by actively digging up information and knowledge about the benefits of elderly gymnastics for health both through elderly posyandu or other more accurate sources

scholarly journals Tingkat pengetahuan lansia berhubungan dengan resiliensi pada lansia yang di tinggal meninggal pasangan hidupnya

2019 ◽  
Vol 7 (2) ◽  
pp. 191
Author(s):  
Sri Puji Lestari ◽  
Sonhaji Sonhaji ◽  
Rosario Alfonsina Baru
Keyword(s):  
Public Health ◽  
Health Center ◽  
Quantitative Research ◽  
The Elderly ◽  
P Value ◽  
Cross Sectional ◽  
Public Health Center ◽  
Stage Of Development ◽  
Work Area ◽  
Cross Sectional Design

Resiliensi merupakan ranah bimbingan pribadi secara sosial kepada individu agar dapat mendaptasi lingkungan sosialya, sehingga mampu mengatasi permasalahan sulit dalam hidupnya dan tetap terbebas dari simtom psikopatologi. Dalam tahap perkembangan usia lanjut sangat diperlukan adanya resiliensi dalam rangka menyesuaikan diri dan bertahan dalam keadaan yang malang dan/atau tidak menyenangkan dalam hidupnya, terlebih untuk para usia lanjut yang ditinggalkan oleh  pasangan hidupnya. Tujuan penelitian ini untuk mengetahui hubungan Tingkat Pengetahuan  Lansia dengan  resiliensi pada lansia yang ditinggalkan karena kemeninggalan oleh pasangan hidupnya di Puskesmas Rowosari Kota Semarang . Metodelogi Penelitian : Jenis penelitian yang kuantitatif dengan rancangan Cross Sectional. Populasi dalam penelitian ini adalah lansia yang sudah ditinggalkan karena kemeninggalan oleh pasangan hidupya di wilayah kerja puskesmas Rowosari Kota Semarang sebanyak 30 responden.Hasil penelitian menunjukkan bahwa Lansia yang ditinggalkan karena kemeninggalan oleh pasangan hidupnya di wilayah kerja Puskesmas Rowosari Kota Semarang yanag mempunyai pengetahuan baik, sebanyak 6 responden (20,0%), pengetahuan cukup, sebanyak 13 responden (43,3%) dan mempunyai resiliensi baik, sebanyak  16 responden (53,3%) dan sebagian kecil mempunyai kejadian resiliensi kurang baik, sebanyak 14 responden (46,7%). Ada hubungan antara pengetahuan dengan resiliensi pada lansia yang ditinggalkan karena kemeninggalan oleh pasangan hidupnya di wilayah kerja Puskesmas Rowosari Kota Semarang dengan p value fisher exact 0,000 < 0,05 Kata kunci: pengetahuan,  lansia,  resiliensi. KNOWLEDGE LEVEL OF ELDERLY RELATED TO  THE RESELIENCE AMONG ELDERLY AFTER THE DEATH OF  A SPOUSE ABSTRACTResilience is the realm of personal social guidance to every individual who has difficultyor problems in his/her life and as well asto support he/she for free from psychopathology symptoms. In the stage of development of the elderly it is necessary to have resilience in order to adapt and survive in a situation that is unfortunate and / or unpleasant in life, especially for the elderly who have been left alone by their partner who had dead.  The purpose of the study: To determine the relationship between the level or degree of knowledge of the elderly with the resilience of the elderly who have been left by  their partner of spouses who dead in Rowosari Public Health Center,  Semarang city,  2017. Type of research, I used quantitative research method by the Cross Sectional design. The population in this study is the elderly who have been left alone by his/her partner who dead in the work area of Rowosari Public Health Center, in Semarang City as many as 30 respondents. The result of the study, Elderly who have been left by his/her partner of spouses who dead in Rowosari Rowosari Public Health Center, Semarang city,  has a good knowledge as much as 6 respondents (20.0%), knowledge enough 13 respondents (43.3%) and have good resilience as many as 16 respondents (53 , 3%) and a small number had an incidence of poor resilience as many as 14 respondents (46.7%). There is a relationship between knowledge with resilience in elderly who have been left by his/her partner of spouses who dead in Rowosari Public Health Center,  Semarang city, with p value fisher exact 0,000 <0,05 Keywords: knowledge, resilienc, elderly

Fluorocitrate Neural Dystrophy of the Guinea Pig Cochlea

1975 ◽  
Vol 33 ◽  
pp. 368-369
Author(s):  
G.J. Spector ◽  
C.D. Carr ◽  
I. Kaufman Arenberg ◽  
R.H. Maisel
Keyword(s):  
Hearing Loss ◽  
Hair Cells ◽  
Sodium Phosphate ◽  
Sensory Cells ◽  
Barium Salt ◽  
Perfusion Medium ◽  
Cochlear Hair Cells ◽  
Neural Degeneration ◽  
Sodium Phosphate Buffer ◽  
Cochlear Neurons

All studies on primary neural degeneration in the cochlea have evaluated the end stages of degeneration or the indiscriminate destruction of both sensory cells and cochlear neurons. We have developed a model which selectively simulates the dystrophic changes denoting cochlear neural degeneration while sparing the cochlear hair cells. Such a model can be used to define more precisely the mechanism of presbycusis or the hearing loss in aging man.Twenty-two pigmented guinea pigs (200-250 gm) were perfused by the perilymphatic route as live preparations using fluorocitrate in various concentrations (15-250 ug/cc) and at different incubation times (5-150 minutes). The barium salt of DL fluorocitrate, (C6H4O7F)2Ba3, was reacted with 1.0N sulfuric acid to precipitate the barium as a sulfate. The perfusion medium was prepared, just prior to use, as follows: sodium phosphate buffer 0.2M, pH 7.4 = 9cc; fluorocitrate = 15-200 mg/cc; and sucrose = 0.2M.

Hubungan Sikap dan Karakteristik Pasangan Usia Subur (PUS) dengan Keikutsertaan dalam Program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur

2020 ◽  
Vol 8 (2) ◽  
pp. 105-114
Author(s):  
Ainul Mardhiah ◽  
Nova Hasbani Prima Dewi ◽  
Aminy Aminy
Keyword(s):  
Family Planning ◽  
Family Planning Program ◽  
The Elderly ◽  
P Value ◽  
Planning Program ◽  
Elderly Age ◽  
Chi Square ◽  
Cross Sectional ◽  
The Family ◽  
Relationship Of

The family planning program also aims to improve the quality of the family in order to generate a sense of security, peace and hope of a better future in realizing the prosperity of birth and inner happiness. Allegedly the factor causing EFA participation in the family planning program is characteristic. The purpose of this research is to know the relationship of attitude and characteristic of Elderly Age Couple (PUS) with participation in family planning program at UPT Puskesmas Sungai Raya Sungai Raya District, East Aceh regency 2018. The research design used was analytic survey with cross sectional design. The population of this study is all Pairs Age of Fertile located in Work Area UPT Sungai Raya Public Health Service Center in January to December 2017 which amounted to 1897 people. Sampling using Slovin formula, obtained as many as 95 samples. The study was conducted from 7-17 July 2018 using questionnaires by interview. Statistical test using chi-square test. Result of research indicate that majority of fertile couple couples (PUS) participate in family planning program as much as 67 respondents (70,5%). Statistically there is relationship of attitude and characteristic of Elderly Age Couple (EFA) with non participation in family planning program in Working Area of UPT Puskesmas Sungai Raya Sungai Raya District of East Aceh Regency 2018 with p value <0,1. It is recommended that the family planning program holders in UPT Puskesmas Sungai Raya Sungai Raya District of East Aceh District to invite cross-sectoral figures to hold meetings to create mini workshop plans at least once a month to increase the participation of the Elderly Age Couple (PUS) in family planning programs. Keyword : Family Planning Program, Attitudes, CharacteristicsABSTRAKProgram KB juga bertujuan untuk meningkatkan kualitas keluarga agar dapat timbul rasa aman, tentram, dan harapan masa depan yang lebih baik dalam mewujudkan kesejahteraan lahir dan kebahagiaan batin. Diduga faktor yang menyebabkan ketidakikutsertaan PUS dalam program KB adalah karakteristik. Tujuan penelitian ini untuk mengetahui hubungan sikap dan karakteristik Pasangan Usia Subur (PUS) dengan keikutsertaan dalam program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur tahun 2018. Desain penelitian yang digunakan adalah survei analitik dengan rancangan bedah lintang. Populasi dari penelitian ini adalah seluruh Pasangan Usia Subur yang berada di Wilayah Kerja UPT Puskesmas Sungai Raya pada bulan Januari sampai dengan Desember tahun 2017 yang berjumlah 1.897 orang. Pengambilan sampel menggunakan rumus Slovin, didapatkan sebanyak 95 sampel. Penelitian dilaksanakan dari tanggal 7-17 Juli tahun 2018 menggunakan kuesioner dengan cara wawancara. Uji statistik menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa mayoritas Pasangan Usia Subur (PUS) ikut serta dalam program KB yaitu sebanyak 67 responden (70,5%). Secara statistik ada hubungan sikap dan karakteristik Pasangan Usia Subur (PUS) dengan ketidakikutsertaan dalam program KB di Wilayah Kerja UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur tahun 2018 dengan p value < 0,1. Sebaiknya pemegang program KB di UPT Puskesmas Sungai Raya Kecamatan Sungai Raya Kabupaten Aceh Timur agar mengajak tokoh lintas sektor agar mengadakan pertemuan untuk membuat rencana loka karya mini setidaknya satu bulan sekali untuk meningkatkan keikutsertaan Pasangan Usia Subur (PUS) dalam program KB.Kata Kunci : Program KB, Sikap, Karakteristik

HUBUNGAN DUKUNGAN KELUARGA, PENGETAHUAN, DENGAN KEAKTIFAN LANJUT USIA (Lansia) MENGIKUTI KEGIATAN POSYANDU LANSIA DI WILAYAH PUSKESMAS GADING SURABAYA

2020 ◽  
Vol 4 (1) ◽  
pp. 1-6
Author(s):  
NINDY VARA MEIGIA
Keyword(s):  
Health Center ◽  
Family Support ◽  
Elderly People ◽  
Simple Random Sampling ◽  
The Elderly ◽  
Design Data ◽  
Cross Sectional ◽  
Bivariate Data ◽  
Quality Regulation ◽  
Cross Sectional Design

Minimum Standards Service is basic service quality regulation that is entitled to be obtained by every citizen. Elderly people must obtain 100% health services. Various factors can lead to low visits to the elderly posyandu in the Gading Puskesmas area in 2017. Objective: to find out the relationship between family support, knowledge, and elderly activities in the elderly posyandu in Gading Surabaya puskesmas. Method: The type of research is observational analytic with a cross-sectional design. Data processing and analysis is done by univariate and bivariate. Data collection techniques by conducting simple random sampling with a sample of 94 elderly people. Location and time of research from December 2018 at the posyandu in the Gading Surabaya health center area. Results: There is a significant value of 0,000 <0,05, so it can be concluded is have a relationship with family support, knowledge of elderly with activity following the elderly posyandu at Gading Surabaya health center

A Cross-Sectional Study of Common Health Problems of the Elderly

2011 ◽  
Vol 4 (5) ◽  
pp. 509-511
Author(s):  
Pranay Gandhi ◽  
◽  
Sunita Sharma ◽  
Prateek Gandhi
Keyword(s):  
The Elderly ◽  
Cross Sectional Study ◽  
Health Problems ◽  
Sectional Study ◽  
Cross Sectional

HUBUNGAN AKTIVITAS FISIK DENGAN FUNGSI KOGNITIF LANSIA DI PANTI WREDHA YAYASAN SOSIAL SALIB PUTIH SALATIGA

2019 ◽  
pp. 137-143
Author(s):  
Dennys Christovel Dese ◽  
Cahyo Wibowo
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
The Elderly ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Significance Level ◽  
The Social ◽  
Normal Cognitive Function ◽  
Intellectual Capacity ◽  
Independent Variable

Peningkatan jumlah lansia setiap tahunnya harus dijadikan perhatian, akibat adanya peningkatan jumlah lansia masalah yang dihadapi akan menjadi semakin kompleks, salah satunya adalah masalah yang berkaitan dengan gejala penuaan. Menurunnya kapasitas intelektual berhubungan erat dengan fungsi kognitif pada lansia. Aktivitas fisik diidentifikasi sebagai salah satu faktor yang mempengaruhi fungsi kognitif. Aktivitas fisik bermanfaat untuk lansia sebagai pencegahan dan demensia. Penelitian ini merupakan penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Penelitian dilakukan di yayasan sosial Panti Wredha Salib Putih Salatiga pada bulan Juni 2018. Populasi dalam penelitian ini adalah lansia yang berumur ?60 tahun. Subjek pada penelitian ini berjumlah 16 responden. Variabel independen dalam penelitian ini adalah aktivitas fisik yang dinilai dengan menggunakan instrument GPAQ. Sedangkan variabel dependen dalam penelitian ini adalah fungsi kognitif yang dinilai dengan instrument MMSE. Terdapat 4 orang (25%) yang masuk dalam kategori fungsi kognitif normal dengan kategori aktifitas fisik sedang 1 orang dan aktifitas berat 3 orang, kemudian yang termasuk dalam kategori gangguan fungsi kognitif ringan sebanyak 11 orang (68,75%), dengan kategori aktifitas fisik sedang 8 orang dan aktifitas ringan 3 orang. Sedangkan yang termasuk dalam kategori gangguan fungsi kognitif berat, terdapat 1 orang (6,25%) dengan kategori aktifitasnya ringan. Taraf signifikansi antar variabel tingkat aktifitas fisik dan fungsi kognitif pada lansia adalah p=0.007 atau p<0,05, sehingga dapat disimpulkan ada  hubungan antara tingkat aktifitas fisik dengan fungsi kognitif pada lansia.   Increasing the number of elderly people every year should be a concern, due to an increase in the number of elderly problems faced will become increasingly complex, one of which is a problem related to the symptoms of aging. Decreased intellectual capacity is closely related to cognitive function in the elderly. Physical activity is identified as one of the factors that influence cognitive function. Physical activity is beneficial for the elderly as prevention and dementia. This study was an observational analytic study using a cross sectional approach. The study was conducted at the social foundation nursing home in the white cross in June 2018. The population in this study was elderly aged ≥60 years. The subjects in this study were 16 respondents. The independent variable in this study is physical activity that is assessed using the GPAQ instrument. While the dependent variable in this study was cognitive function which was assessed by the MMSE instrument. There are 4 people (25%) who fall into the category of normal cognitive function with moderate physical activity categories 1 person and heavy activities 3 people, then those included in the category of mild cognitive function disorders are 11 people (68.75%), with the category of physical activity being 8 people and 3 light activities. While those included in the category of severe cognitive function disorders, there is 1 person (6.25%) with a mild activity category. The significance level between the level of physical activity and cognitive function in the elderly is p = 0.007 or p <0.05, so it can be concluded that there is a relationship between the level of physical activity and cognitive function in the elderly.

PHYSICAL, SOCIAL ACTIVITIES AND QUALITY OF LIFE OF THE ELDERLY LIVING IN TRUONG AN WARD, HUE CITY IN 2016

2019 ◽  
pp. 55-62
Author(s):  
Vuong Diem Khanh Doan ◽  
Ngoc Minh Chau Ho ◽  
Thi Van Ngo ◽  
Thi Bao Nga Phan ◽  
Thi Hong Phan Nguyen
Keyword(s):  
Quality Of Life ◽  
The Elderly ◽  
Total Sample ◽  
Cross Sectional Study ◽  
Physical Activities ◽  
Social Activities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elderly Living

Background: Vietnam is entering the stage of aging population; as a result, the quality of life (QOL) of the elderly is really a matter of concern. There is a great deal of research on the quality of life of the elderly while Vietnam witnesses a lack of research on this topic, especially on how physical and social activities have impact on QOL of the elderly. Objectives: (1) To describe the situation of participation in physical, social activities and QOL of the elderly residing in Truong An Ward, Hue city. (2) To examine the association between physical, social activities and QOL among participants. Methodology: This study used cross-sectional study design. A total sample of 420 people aged 60 and above in Truong An Ward, Hue city were interviewd. The SF36 was used to measure the QOL of participants. Results: Percentage of the elderly taking part in physical activity were 66%. 49% reported having the habit of taking part in social activities. The majority of the elderly get their QOL level in three health fields, namely physical, mental and general health at above average. (56.0, 60.7 and 60.8 respectively). There were significant associations between physical activities, social activities and QOL among participants. Conclusion: The percentage of the elderly taking part in physical and social activities were still low. Besides, QOL of the elderly at the research location was not really high. It’s important to encourage the elderly taking part in physical and social activities to improve their quality of life. Key words: Physical activities, social activities, QOL, the elderly

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