scholarly journals An Updated Review on Phyto-Pharmacological and Pharmacognostical Profile Of Buchanania Lanzan : A Pharmacognostic Miracle Herb

2021 ◽  
pp. 298-310
Author(s):  
Akila Elias ◽  
Prasanna V Habbu ◽  
Sudhir Iliger
Keyword(s):  
Complete Information ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Priority Areas ◽  
Toxicity Studies ◽  
Current Review ◽  
Phytochemical Investigation ◽  
Indian Tribes

Buchanania lanzan (Anacardiaceae) is a miracle herb widely used by Indian tribes for treating various diseases. Aim of the current review is to search literature for the pharmacological properties, pharmacognostic studies and phytochemical investigation of Buchanania lanzan. The compiled data may be helpful for the researchers to focus on the priority areas of research yet to be discovered. Complete information about the plant has been collected from various books and journals. Particulars of pharmacological activities, phytochemical isolation, toxicity studies etc. ongoing and emerging areas of research of this plant, especially in the field of phytomedicnes and pharmaceuticals was concluded in the review.

scholarly journals A PHARMACOGNOSTIC AND PHARMACOLOGICAL REVIEW ON CHROMOLAENA ODORATA (SIAM WEED)

2018 ◽  
Vol 11 (10) ◽  
pp. 34
Author(s):  
Vanita Kanase ◽  
Sana Shaikh
Keyword(s):  
Skin Diseases ◽  
The United States ◽  
Pharmacological Properties ◽  
Chromolaena Odorata ◽  
Pharmacological Activities ◽  
Tropical Asia ◽  
Current Review ◽  
Young Leaves ◽  
The Caribbean ◽  
Important Medicinal Plant

Chromolaena odorata is commonly known as Siam weed which belongs to sunflower family Asteraceae. C. odorata is an important medicinal plant which can be easily found in tropical Asia, West Africa, and parts of Australia. It is native to the America, and found in Florida and Texas in the United States, throughout Mexico and the Caribbean to South America. The medicinal usage of C. odorata has been reported in the traditional systems of medicine such as Ayurveda, Siddha, and Unani. It has wide variety of ethanomedicinal and pharmacological properties. The young leaves are crushed, and the resulting liquid can be used to treat skin wounds. The leaves extract is used by the kani tribals of Kouthalai in Tirunelveli hills to cure skin diseases, poison bites, wounds, and rheumatism. Following various folk claims for the ailment of various diseases, efforts have been made by the researchers to verify the efficacy of this weed through scientific biological screenings. A study of the literature revealed some notable pharmacological activities of the shrub such as anthelmintic, antimalarial, analgesic, anti-inflammatory, antipyretic, antispasmodic, antioxidant, antigonorrheal, antimycobacterial, insecticidal, fungicidal, wound healing, diuretic, blood coagulation, and antibacterial. The current review is created with an intent to focus on the numerous ethnobotanical and traditional uses as well as the phytochemical and pharmacological reports on C. odorata.

scholarly journals PHYTOCHEMICAL AND PHARMACOLOGICAL ACTIVITIES OF JUSTICIA PROCUMBENS L.: A REVIEW

2020 ◽  
Vol 11 (5) ◽  
pp. 190-193
Author(s):  
Amritha C K ◽  
Suma C ◽  
Ananya V M ◽  
Thushara P V ◽  
Deepak V S
Keyword(s):  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Active Compounds ◽  
Traditional Uses ◽  
Current Review ◽  
Snake Bites ◽  
Anti Inflammatory ◽  
Water Willow ◽  
Anti Hiv

Justicia procumbens L. is usually known as water willow which belongs to family Acanthaceae growing widely in southern regions of China, Japan, Vietnam, India and Australia. It is one of the important herbal being used in Ayurvedic system of medicine. The plant contains various active compounds like arylnaphthalide and diarylbutane lignans, glycosides, flavonoids. Few pharmacological properties including anti-inflammatory, anti-arthritic, anti-arrhythmic, anti-asthmatic, anti-proliferative, anti-allergic, antibacterial, cytotoxic and anti-HIV activities activity have been reported for this plant. Conventionally, it is used for the treatment of fever, inflammation, cold, cough, asthma, cancer, snake bites etc. The current review is created with an intended to focus on the numerous ethnobotanical and traditional uses as well as the phytochemical and pharmacological report on Justicia procumbens.

Exploring the Chemistry and Therapeutic Potential of Triazoles: A Comprehensive Literature Review

2019 ◽  
Vol 19 (16) ◽  
pp. 1298-1368 ◽  
Author(s):  
Ankit Jain ◽  
Poonam Piplani
Keyword(s):  
Oxidative Stress ◽  
Drug Discovery ◽  
Literature Review ◽  
Structural Modification ◽  
Therapeutic Potential ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Triazole Derivatives ◽  
Comprehensive Literature Review ◽  
The Common

: Triazole is a valuable platform in medicinal chemistry, possessing assorted pharmacological properties, which could play a major role in the common mechanisms associated with various disorders like cancer, infections, inflammation, convulsions, oxidative stress and neurodegeneration. Structural modification of this scaffold could be helpful in the generation of new therapeutically useful agents. Although research endeavors are moving towards the growth of synthetic analogs of triazole, there is still a lot of scope to achieve drug discovery break-through in this area. Upcoming therapeutic prospective of this moiety has captured the attention of medicinal chemists to synthesize novel triazole derivatives. The authors amalgamated the chemistry, synthetic strategies and detailed pharmacological activities of the triazole nucleus in the present review. Information regarding the marketed triazole derivatives has also been incorporated. The objective of the review is to provide insights to designing and synthesizing novel triazole derivatives with advanced and unexplored pharmacological implications.

Natural Products for Regulating Macrophages M2 Polarization

2020 ◽  
Vol 15 (7) ◽  
pp. 559-569 ◽  
Author(s):  
Zhen Chang ◽  
Youhan Wang ◽  
Chang Liu ◽  
Wanli Smith ◽  
Lingbo Kong
Keyword(s):  
Molecular Mechanisms ◽  
Inflammatory Diseases ◽  
Therapeutic Strategies ◽  
Research Progress ◽  
Cellular Mechanisms ◽  
Pharmacological Activities ◽  
Current Review ◽  
M2 Polarization ◽  
Macrophages Polarization ◽  
Herbal Plants

Macrophages M2 polarization have been taken as an anti-inflammatory progression during inflammation. Natural plant-derived products, with potential therapeutic and preventive activities against inflammatory diseases, have received increasing attention in recent years because of their whole regulative effects and specific pharmacological activities. However, the molecular mechanisms about how different kinds of natural compounds regulate macrophages polarization still unclear. Therefore, in the current review, we summarized the detailed research progress on the active compounds derived from herbal plants with regulating effects on macrophages, especially M2 polarization. These natural occurring compounds including flavonoids, terpenoids, glycosides, lignans, coumarins, alkaloids, polyphenols and quinones. In addition, we extensively discussed the cellular mechanisms underlying the M2 polarization for each compound, which could provide potential therapeutic strategies aiming macrophages M2 polarization.

scholarly journals Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marjan Talebi ◽  
Mohsen Talebi ◽  
Tahereh Farkhondeh ◽  
Jesus Simal-Gandara ◽  
Dalia M. Kopustinskiene ◽  
...  
Keyword(s):  
Blood Cells ◽  
Molecular Mechanisms ◽  
Web Of Science ◽  
Experimental Studies ◽  
Protective Effects ◽  
Pharmacological Activities ◽  
Current Review ◽  
Mesh Terms ◽  
Online Databases ◽  
Anti Cancer

AbstractChrysin has been shown to exert several beneficial pharmacological activities. Chrysin has anti-cancer, anti-viral, anti-diabetic, neuroprotective, cardioprotective, hepatoprotective, and renoprotective as well as gastrointestinal, respiratory, reproductive, ocular, and skin protective effects through modulating signaling pathway involved in apoptosis, oxidative stress, and inflammation. In the current review, we discussed the emerging cellular and molecular mechanisms underlying therapeutic indications of chrysin in various cancers. Online databases comprising Scopus, PubMed, Embase, ProQuest, Science Direct, Web of Science, and the search engine Google Scholar were searched for available and eligible research articles. The search was conducted by using MeSH terms and keywords in title, abstract, and keywords. In conclusion, experimental studies indicated that chrysin could ameliorate cancers of the breast, gastrointestinal tract, liver and hepatocytes, bladder, male and female reproductive systems, choroid, respiratory tract, thyroid, skin, eye, brain, blood cells, leukemia, osteoblast, and lymph. However, more studies are needed to enhance the bioavailability of chrysin and evaluate this agent in clinical trial studies. Graphic abstract

scholarly journals Rivea Hypocrateriformis (Desr.) Choisy: A Review of its Ethnomedicinal Uses, Phytochemistry and Biological Activities

2021 ◽  
Author(s):  
Mohammad Mukim ◽  
Atul Kabra ◽  
Christophe Hano ◽  
Samantha Drouet ◽  
Duangjai Tungmunnithum ◽  
...  
Keyword(s):  
Sri Lanka ◽  
Organic Compounds ◽  
Skin Disease ◽  
Biological Activities ◽  
Snake Bite ◽  
Pharmacological Activities ◽  
Traditional Uses ◽  
Phytochemical Investigation ◽  
Long Time ◽  
Ethnomedicinal Uses

Rivea hypocrateriformis (Desr.) Choisy is a robust woody climbing shrub of the genus Rivea which is found in India, Nepal, Sri Lanka, Pakistan, Bangladesh, Myanmar and Thailand. R. hypocrateriformis is a promising medicinal herb with enormous helpful and wellbeing advancing impacts. R. hypocrateriformis has been utilized as a customary medication for a long time to treat rheumatic pain, fever, urogenital problem, snake bite, cough, piles, malaria, and skin disease. Apart from the traditional uses its leaves and young shoots are cooked and eaten as a vegetable and for preparation of bread with millet flour. This review comprehensively summarizes the up-to-date information on the botanical characterization, distribution, traditional uses, phytochemistry, pharmacology and toxicity study of R. hypocrateriformis. Phytochemical investigation has been revealed that alkaloids, glycosides, coumarins, flavonoids, xanthones, stilbenes, and other organic compounds are contained in R. hypocrateriformis. Crude extracts and isolated compounds have exhibited numerous pharmacological activities such as anovulatory effect, antifertility activity, antiarthritic, antimicrobial, anticancer, antioxidant, hepatoprotective, antilithiatic, antimitotic. R. hypocrateriformis is a promising restorative spice with monstrous remedial and wellbeing advancing impacts. Along these lines, further investigations on the bioactive mixtures and systems of R. hypocrateriformis are justified. Extra clinical and toxicological examinations are expected to assess its wellbeing.

Pharmacological Importance of Chromolaena odorata: a review

2021 ◽  
pp. 8-11
Author(s):  
Angitha Ajay ◽  
Rupesh Kumar M ◽  
Shamal Badhusha PA ◽  
Abhishek K ◽  
Sanjay K Gowda ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
West Africa ◽  
Pharmacological Properties ◽  
Conventional System ◽  
Chromolaena Odorata ◽  
Pharmacological Activities ◽  
Tropical Asia ◽  
Clinical Investigations ◽  
Medicinal Use ◽  
Medicinal Properties

Chromolaena odorata (Asteraceae) is commonly referred to as Siam Weed, a major medicinal plant found in tropical Asia, Australia, and West Africa. The medicinal use of Chromolaena odorata had been documented in the conventional system such as the Siddha, Unani, Ayurveda. The pharmacological properties of this plant are widely varying. A wide variety of attractive but limited compounds were extracted from this Chromolaena odorata and the pharmacological  activities   were   screened   out.   This   review   the   various   properties  of Chromolaena odorata and focus on its various medicinal properties. It is an attractive subject for further experimental and clinical investigations. This article will give an exhaustive summary and analysis of Chromolaena odorata pharmacological activities. The present article including the detailed exploration of pharmacological properties of C. odorata is an attempt to provide a direction for further research.

Medicinal Inula Species: Phytochemistry, Biosynthesis, and Bioactivities

2021 ◽  
pp. 1-44
Author(s):  
Cheng-Peng Sun ◽  
Zi-Li Jia ◽  
Xiao-Kui Huo ◽  
Xiang-Ge Tian ◽  
Lei Feng ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Drug Development ◽  
Scientific Basis ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
The World ◽  
Phytochemical Constituents ◽  
New Drug Development ◽  
First Time

As a genus of the Asteraceae, Inula is widely distributed all over the world, and several of them are being used in traditional medicines. A number of metabolites were isolated from Inula species, and some of these have shown to possess ranges of pharmacological activities. The genus Inula contains abundant sesquiterpenoids, such as eudesmanes, xanthanes, and sesquiterpenoid dimers and trimers. In addition, other types of terpenoids, flavonoids, and lignins also exist in the genus Inula. Since 2010, more than 300 new secondary metabolites, including several known natural products that were isolated for the first time from the genus Inula. Most of them exhibited potential bioactivities in various diseases. The review aimed to summarize the advance of recent researches (2010–2020) on phytochemical constituents, biosynthesis, and pharmacological properties of the genus Inula for providing a scientific basis and supporting its application and exploitation for new drug development.

scholarly journals Natural Products, Traditional Uses and Pharmacological Activities of the Genus Biebersteinia (Biebersteiniaceae)

Plants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 595 ◽  
Author(s):  
Benyin Zhang ◽  
Xiaona Jin ◽  
Hengxia Yin ◽  
Dejun Zhang ◽  
Huakun Zhou ◽  
...  
Keyword(s):  
Natural Products ◽  
Molecular Mechanisms ◽  
Chemical Properties ◽  
Pharmacological Properties ◽  
Pharmacological Activities ◽  
Drug Discovery And Development ◽  
Chemical Structures ◽  
Traditional Uses ◽  
Novel Drugs ◽  
Major Chemical

Medicinal plants have been known as a rich source of natural products (NPs). Due to their diverse chemical structures and remarkable pharmacological activities, NPs are regarded as important repertoires for drug discovery and development. Biebersteinia plant species belong to the Biebersteiniaceae family, and have been used in folk medicines in China and Iran for ages. However, the chemical properties, bioactivities and modes of action of the NPs produced by medicinal Biebersteinia species are poorly understood despite the fact that there are only four known Biebersteinia species worldwide. Here, we reviewed the chemical classifications and diversity of the various NPs found in the four known Biebersteinia species. We found that the major chemical categories in these plants include flavonoids, alkaloids, phenylpropanoids, terpenoids, essential oils and fatty acids. We also discussed the anti-inflammatory, analgesic, antibacterial, antioxidant, antihypertensive and hypoglycemic effects of the four Biebersteinia species. We believe that the present review will facilitate the exploration of traditional uses and pharmacological properties of Biebersteinia species, extraction of the NPs and elucidation of their molecular mechanisms, as well as the development of novel drugs based on the reported properties and mode-of-action.

scholarly journals Icacina trichantha, A Tropical Medicinal Plant

2016 ◽  
Vol 11 (7) ◽  
pp. 1934578X1601100
Author(s):  
Chun-Tao Che ◽  
Ming Zhao ◽  
Brian Guo ◽  
Michael M. Onakpa
Keyword(s):  
Chemical Composition ◽  
Animal Models ◽  
Chemical Analysis ◽  
Medicinal Plant ◽  
West Africa ◽  
Pharmacological Properties ◽  
Good Source ◽  
Pharmacological Activities

This is a review on the pharmacological properties and chemical composition of Icacina trichantha (Icacinaceae), a food and medicinal plant native to West Africa. The tuber is a good source of nutrients such as starch; it also exhibits a variety of pharmacological activities in animal models. Chemical analysis has revealed the presence of a series of unusual pimarane-type diterpenes.

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