scholarly journals Antimicrobial Sensitivity Profile Of Uropathogens In A Macapá Laboratory, Amapá, Brazilian Amazon

2021 ◽  
pp. 81-102
Author(s):  
Ítalo Fernando Penha da Silva ◽  
José Maria Henriques Serruya Júnior ◽  
Tayonara Borges Gonçalves Góes ◽  
Bruno Gomes de Noronha ◽  
Cláudio Alberto Gellis de Mattos Dias ◽  
...  
Keyword(s):  
Protective Factor ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Population ◽  
E Coli ◽  
Antimicrobial Sensitivity ◽  
Private Laboratory ◽  
Predominant Pathogen ◽  
Tract Infections

Urinary tract infections (UTI) represent a worldwide health problem. Microbial resistance, due to selective antibiotic pressure, has a direct influence on the evolution and impact of these infections. The objective of this work was to identify the antimicrobial susceptibility profile of uropathogens isolated in uroculture samples from a private laboratory in the city of Macapá/AP. It is a quantitative, retrospective and cross-sectional study, using a laboratory database. Data were collected from results of urocultures with antibiogram analyzed from January to December 2019. The present study evaluated 3,510 urocultures, carried out during the study period, of which 1,269 had bacterial growth, equivalent to 36.15%. Among the positive results, we found the bacteria Escherichia coli (66.59%), Staphylococcus aureus (32.62%), mixed colonies of E. coli and S. aureus (0.47%), Staphylococcus saprophyticus (0.24%) and Serratia marcescens (0.08%). The male gender was responsible for 16.35% (n = 574) of the urocultures analyzed, while the female population was 83.65% (n = 2936). When analyzing the distribution of bacteria isolated by gender, males were considered a protective factor with 42% less chance of presenting bacteria in urine. The bacteria E. coli was the predominant pathogen in these infections in both sexes and in all age groups.

scholarly journals A cross-sectional study on morbidity status among school going adolescents in Thiruvallur district, Tamil Nadu

2019 ◽  
Vol 6 (12) ◽  
pp. 5201
Author(s):  
Sathish Dev D. ◽  
Sugantha Valli M. ◽  
Gnana Sezhian M. ◽  
Suganya E.
Keyword(s):  
Tamil Nadu ◽  
Gastrointestinal Disease ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Health Problems ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Wide Range ◽  
Tract Infections

Background: Adolescents represent about 21.8 percent of India’s population. Various health risks with potentially life-threatening consequences become prominent in this age group. This study was undertaken with the objective to determine the morbidity profile of school going adolescents in Tamil Nadu.Methods: This descriptive, cross sectional study was planned and conducted from January 2016 to August 2017. The study population included 987 adolescent boys and girls aged between 10 to 19 years studying in high and higher secondary Government schools of Thiruvallur district of Tamil Nadu. Semi-structured questionnaire was used as data collection tool.Results: The mean age groups of this school going adolescent are 14.2 yrs. In the present study 583 (59%) of the study participants were affected by one or more morbidity condition. Among them, 395 (67.7%) were in the age group 10-14 years and 188 (32.2%) in the age group 15-19 years. 122 (21%) and 461 (79.1%) of male and female were affected respectively. In the present study, fever (21%) was the commonest reported morbidity followed by acute respiratory infection (15.7%) and acute gastrointestinal disease (13. 4%).Conclusions: This study shows that adolescents are prone to a wide range of morbidity conditions. Apart from respiratory and gastro intestinal diseases, reproductive tract infections and sexual health problems are important morbidities affecting this age group. There is strong need to sensitize health care practitioners at all levels, in both government and private sectors towards health problems in adolescent age groups.

Local characteristics associated with higher prevalence of ESBL-producing Escherichia coli in community-acquired urinary tract infections: an observational, cross-sectional study

2020 ◽  
Author(s):  
Stéphanie Larramendy ◽  
Aurélie Gaultier ◽  
Jean-Pascal Fournier ◽  
Jocelyne Caillon ◽  
Leïla Moret ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract ◽  
Agricultural Land ◽  
Cross Sectional Study ◽  
Urine Samples ◽  
Sectional Study ◽  
Cross Sectional ◽  
E Coli ◽  
Animal Farming ◽  
Tract Infections

Abstract Objectives The prevalence of ESBL-producing Escherichia coli (ESBL-E. coli) in community-acquired urinary tract infections (UTI) has been increasing worldwide since 2000, but with large geographical variations. The aim of this study was to determine whether the ESBL-E. coli rate in urine samples from individuals with community-acquired UTI was associated with the local socio-economic, environmental, agricultural and healthcare characteristics. Methods This was a cross-sectional study in western France using data on antibiotic susceptibility of E. coli isolated from urine samples of individuals with community-acquired UTI analysed in non-hospital laboratories from 2015 to 2017. The ESBL-E. coli rate was calculated for each laboratory. Data on socio-economic characteristics, human antibiotic consumption, hospital bed density, animal farming density and percentage of agricultural land and surface water were retrieved at the municipality level and aggregated by study area. Their association with ESBL-E. coli prevalence was quantified using multivariate linear regression models with a backward selection. Results From 358 291 E. coli isolates from urine samples tested in 92 laboratories, the mean ESBL-E. coli prevalence for the study period was 3.30%. In an adjusted model, the ESBL-E. coli rate was significantly (P < 0.05) and positively associated with the local percentage of people >65 years old, third-generation cephalosporin use (DDD/1000 inhabitants), number of hospital beds/km2, poultry density, pig density and percentage of agricultural land. Lower deprivation was associated with a higher ESBL-E. coli rate. Conclusions Several anthropogenic factors (primary care, hospitals and animal farming) are associated with the local ESBL-E. coli rate in community-acquired UTI. These results could contribute to improve risk management, including identification of at-risk patient groups.

scholarly journals Sickness and Treatment: A Situation Analysis among the Garments Workers

2013 ◽  
Vol 4 (1) ◽  
pp. 10-14 ◽  
Author(s):  
Md Atiqur Rahman ◽  
Md Mahfuzar Rahman
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
Health Care Facilities ◽  
Cross Sectional ◽  
Duration Of Illness ◽  
Care Facilities ◽  
Seeking Behavior ◽  
The Mean ◽  
Tract Infections ◽  
Scientific Treatment

This was a descriptive type of cross sectional study among 522 garments workers as  respondents. It was aimed to identify morbidity pattern, duration of illness among garments  workers and also to determine treatment seeking behavior during illness. The socio-demographic  characteristics of the respondents were the points of investigations.  It was revealed from the findings that the mean age of the respondents were 23.1years. They  were mostly female (80%) and married (60%). About 60% respondents were found primarily  educated and no one found illiterate. 90% respondents were found from nucleated family. The  study shows 79% respondents were suffering from illness during the last 02 months and majority  suffers (18.6%) and (43.6%) were found among 26-30 years age groups and 21-25 years age  groups respectively. However, female sufferers were more (33.6%) than male (10%) in the 21-  25 years age groups. Moreover about 42% respondents were suffering for 1-2 weeks and 28.8  are suffering for less than 02 weeks. On the otherhands, Loose motion, Cough, and  Breathlessness were found prominent sign/symptoms among 38%, 29%, 28% sufferers  respectively. Diarrhoea, Common cold and Respiratory Tract Infections were found as  predominant diagnosis among 40.5%, 22.5% & 15.1% respondents respectively. Nevertheless  majority 56% were seeking treatment from LMAF doctors. Conclusion: The study findings  highlight awareness program among factory owners and garments workers towards preventing  infectious and chronic diseases as well as to undertake modern scientific treatment. Improved  health care facilities in the garments factory may be considered for early detection and treatment  of cases to avoid complications. DOI: http://dx.doi.org/10.3329/akmmcj.v4i1.13678 AKMMC J 2013: 4(1): 10-14

scholarly journals The effect of religiosity during childhood and adolescence on drug consumption patterns in adults addicted to crack cocaine

BJPsych Open ◽  
2018 ◽  
Vol 4 (5) ◽  
pp. 324-331 ◽  
Author(s):  
Alexandre Rezende-Pinto ◽  
Alexander Moreira-Almeida ◽  
Marcelo Ribeiro ◽  
Ronaldo Laranjeira ◽  
Homero Vallada
Keyword(s):  
Odds Ratio ◽  
Protective Factor ◽  
Crack Cocaine ◽  
Age Groups ◽  
Religious Involvement ◽  
Cross Sectional Study ◽  
Drug Consumption ◽  
Consumption Patterns ◽  
Childhood And Adolescence ◽  
Cross Sectional

BackgroundAlthough many studies suggest that religiosity is a protective factor against drug use, there is little information on its effect on drug consumption patterns of those who do use drugs.AimsWe aimed to examine if there is any relationship between religiosity during childhood and adolescence, and drug consumption in adult crack users.MethodWe performed a cross-sectional study of adults addicted to crack cocaine. Logistic regression analysis was used to estimate the odds ratio for the association between religious history in the age groups 8–11, 12–14 and 15–17 years and outcome variables.ResultsFrom a total of 531 respondents, religious involvement during childhood and adolescence was correlated to less frequent onset of drug consumption before 18 years (odds ratio 0.95, 95% CI 0.92–0.98) and less craving (odds ratio 0.95, 95% CI 0.91–0.99), mainly between the ages of 15 and 17 years.ConclusionsReligiosity provides some protection against drug consumption patterns in crack cocaine addicts.Declaration of interestNone.

scholarly journals Multidrug-resistant urinary tract isolates of escherichia coli: Frequency and patient demographics in a Tertiary Care Hospital.

2020 ◽  
Vol 27 (02) ◽  
pp. 335-340
Author(s):  
Salman Azhar ◽  
Muhmmad Wasif Baig ◽  
Shahid Rasool ◽  
Rizwan Rasool Khan ◽  
Talha Munir ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Multidrug Resistant ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
E Coli ◽  
Patient Demographics ◽  
Tract Infections

Urinary tract infections (UTIs) are a major burden to the health care as it is estimated that around 150 million UTIs occur yearly worldwide. Enterobacteriaceae are the most common agent causing serious urinary tract infections; and MDR cases are increasing day by day. Objectives: To determine the frequency and patient demographics of multidrug resistant urinary tract isolates of Escherichia Coli in a Tertiary Care Hospital. Study Design: Retrospective cross sectional study. Setting: Medicine Department of Madinah Teaching Hospital / The University of Faisalabad, Faisalabad. Period: From May 2016 to Sep 2018. Material & Methods: 187 patients of age 15 to 90 years with positive E. coli on urine culture and sensitivity were included in this Retrospective cross sectional study. All those patients with history of dysuria (pain during urination) or frequent urination (more than 7 times per day) were advised urine complete analysis and those with >5 WBCs or pus cells /HPF or having positive for leukocyte esterase and/or nitrite, were advised urine culture and sensitivity. Main outcome variable was the frequency of MDRE cases among the culture positive E. coli UTI patients. Results: Among all the cases of E. coli UTI, frequency of MDRE UTI was 66.8% (n=125) and rest 33.2% (n= 62) cases were not MDR UTI. 97.3% patients were resistant to lactam antibiotics, 95.7% were resistant to quinolones and 68.4% were resistant to aminoglycosides.

scholarly journals Evaluation of Urine Isolated Bacteria and Their Antimicrobial Resistance in Hospitalized Patients in Ahvaz Golestan Hospital in 2019

2021 ◽  
Vol 20 (2) ◽  
pp. 128-139
Author(s):  
Ladan Fatahi ◽  
Mohammad Soleymani Zar ◽  
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Relevant Information ◽  
Cross Sectional Study ◽  
Hospitalized Patients ◽  
Urine Samples ◽  
Cross Sectional ◽  
E Coli ◽  
Tract Infections

Background and Objectives: Urinary Tract Infection (UTI) is one of the most common infections in the community and hospitalized patients. The aim of the present study was to investigate bacteria isolated from urinary tract infections and their antibiotic resistance in hospitalized patients. Subjects and Methods In the this descriptive-cross-sectional study, the results of about 5,000 urine samples sent for culture from the hospitalized patients of Golestan Hospital in Ahvaz in 2019 were examined. Relevant information was extracted from patients’ medical records. Results Out of 5000 samples studied (39.7% female and 60.3% male), about 468 samples (9.36%) showed positive urine culture. Of the patients with UTI, 205 patients were women (43.8%). The risk of UTI increased with age. The most common bacteria caused urinary tract infections were E. coli with 51.5%, followed by Klebsiella with 29.3%. It was also observed that bacteria isolated from urine samples of people with UTI had antibiotic resistance, and for each bacteria special groups of antibiotics were more effective. Conclusion The prevalence of UTI in the studied patients was 9.36%. In females and with increasing age, the prevalence of UTI was higher. The most common bacteria that caused UTI were E. coli and then Klebsiella. Due to the fact that the resistance and sensitivity of bacteria to antibiotic used, it is recommended that the most common bacterial agents of UTI must be diagnosed and then the most appropriate antibiotic must be prescribed

scholarly journals Frequency Distribution of Hepatitis C Virus Genotypes with Reference to Age and Sex in Various Districts of Khyber Pakhtunkhwa, Pakistan

2021 ◽  
pp. 83-88
Author(s):  
Bakht Biland ◽  
Mohsina Haq ◽  
Sardar Muhammad ◽  
Mohsan Subhani ◽  
Syed Gardezi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Population ◽  
Khyber Pakhtunkhwa ◽  
Significant Difference ◽  
Age And Sex ◽  
Genotype 3A

Background: Pakistan has the second highest prevalence of hepatitis C in the world after Egypt. Viral hepatitis is a leading cause of morbidity and mortality in Pakistan and, worryingly, reinfection rates are also on the rise. This cross-sectional study was aimed at finding the most common genotypes of hepatitis C in terms of age and sex in a Pakistani cohort. Materials and methods: The authors collected blood samples from 1,260 patients with diagnosed hepatitis C visiting a primary teaching hospital affiliated with Peshawar Medical College, Pakistan, from different districts of Khyber Pakhtunkhwa, Pakistan, between January 2017 and April 2019. Hepatitis C virus RNA was quantified by real-time polymerase chain reaction and genotyping was then performed. Results: The authors found that genotype 3a was the most prevalent type followed by 1a, mixed, and 3b, respectively. Genotypes 2a and 1b were the least prevalent in Khyber Pakhtunkhwa. The most common genotype was 3a, observed in 75.87% of cases. The most common mixed genotype was 3a+1a, observed in 39 cases (3.10%); it had a prevalence of 3.49% in females compared with 2.70% in males. Overall, the most common age group affected by hepatitis C virus was 41–50 years (31.35%), followed by the 51–60 years group (24.45%). Infection rate was comparatively low in other age groups. A significant difference was observed in the prevalence of genotype 3a and 2a among different districts. Conclusion: The authors concluded that genotype 3a was the most prevalent genotype and it was observed more frequently in the female population, with a median age of 45 years.

scholarly journals Bacterial Profile and Antibiotic Resistance among Cancer Patients with Urinary Tract Infection in a National Tertiary Cancer Hospital of Nepal

2021 ◽  
Vol 6 (2) ◽  
pp. 49
Author(s):  
Gambhir Shrestha ◽  
Xiaolin Wei ◽  
Katrina Hann ◽  
Kyaw Thu Soe ◽  
Srinath Satyanarayana ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Cancer Patients ◽  
Positive Culture ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Antibiotic Resistant ◽  
E Coli ◽  
Cancer Hospital ◽  
Tract Infections

Cancer patients are at high risk of antibiotic resistant bacterial urinary tract infections (UTIs). In this study, we assessed the bacterial profile and antibiotic resistance among cancer patients suspected of UTI in B.P. Koirala Memorial Cancer Hospital in Nepal through a cross-sectional study with routinely collected data. All cancer patients who had a recorded urine culture between July 2018–June 2019 were included in the study. Out of 308 patients who had undergone culture, 73 (24%) of samples had bacterial growth. The most common organisms isolated were E. coli (58%), Staphylococcus (11%) and Klebsiella (10%). These bacteria had undergone susceptibility testing to 27 different antibiotics in various proportions. Of the limited antibiotic testing levels, nitrofurantoin (54/66, 82%) and amikacin (30/51, 59%) were the most common. Among those tested, there were high levels of resistance to antibiotics in the “Access” and “Watch” groups of antibiotics (2019 WHO classification). In the “Reserve” group, both antibiotics showed resistance (polymyxin 15%, tigecycline 8%). Multidrug resistance was seen among 89% of the positive culture samples. This calls for urgent measures to optimize the use of antibiotics in UTI care at policy and health facility levels through stewardship to prevent further augmentation of antibiotic resistance among cancer patients.

scholarly journals PREVALENCE, DISTRIBUTION AND DETERMINANTS OF ESCHERICHIA COLI RESISTANCE TO CEFTRIAXONE IN ADULT INDOOR UTI POPULATION OF DISTRICT PESHAWAR, PAKISTAN

2020 ◽  
Vol 18 (2) ◽  
pp. 45-53
Author(s):  
Ubed Ullah ◽  
Kiran Javed ◽  
Muhammad Asim Khan ◽  
Imran Ullah ◽  
Noor Ul Iman
Keyword(s):  
Goodness Of Fit ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Older Age ◽  
Age Group ◽  
Chi Square ◽  
Cross Sectional ◽  
E Coli ◽  
Younger Age ◽  
Chi Square Test

Background: Escherichia coliresistance to ceftriaxone in UTIs is an emerging health problem.Our objectives were to determine prevalence, distribution and determinants of E. coliresistance to ceftriaxone in adult indoor UTI population of District Peshawar, Pakistan. Materials & Methods:This cross-sectional study was conducted in Department of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan from 1st January 2017 to 30th June 2017. 380 UTIs cases were selected from population at riskconsecutively.Sex and age groups were demographic, while presence of E. coli resistance to ceftriaxone was research variable. All variables were nominal.Prevalenceand distribution were analyzed by count, percentage and confidence intervals for proportion for population. Hypotheses for distribution were substantiated by chi-square goodness-of-fit and of association by chi-square test of association. Results: Out of 380 patients with UTI, 136 (35.80%) were men,244(64.20%) women, 262 (68.95%) in age group 18-45 years and 118 (31.05%) in age group 46-65 years. Frequency/ prevalence of E. coli resistance was 287/380 (75.53%, 95%CI 71.20-79.85). Out of 287 patients with E. coli resistance to ceftriaxone, 101 (26.58%) were men and 186 (48.95%) women, 198 (52.11%) in age group 18-45 years and 89 (23.42%) in age group 46-65 years. Our prevalence of E. coli resistance to ceftriaxone was higher than expected (p<.00001), our distribution by sex(p<.00125) and age groups (p<.00001) were different than expected. Presence of E. coli resistance to ceftriaxone was not associated to sex (p=.669333) and age groups (p=.975097). Conclusion:Prevalence of E. coli resistance to ceftriaxone in adult UTI population of District Peshawar, Pakistan was alarmingly high 75.53%. Prevalence was more in women than men and more in younger age group (18-45 years) than older age group (46-60 years) population.Overall prevalence of E. coli resistance to ceftriaxone was higher than expected. Distribution by sex showed higher prevalence than expected in men and lower than expected in women, and higher than expected in younger age group and lower than expected in older age group. Presence of E. coli resistance to ceftriaxone was not associated to sex and age groups respectively in adult UTI population of District Peshawar, Pakistan.

scholarly journals Prevalence of Cervical Cancer among Cervical Biopsies in a Tertiary Care Center

2020 ◽  
Vol 58 (227) ◽  
Author(s):  
Ganesh Parajuli ◽  
Pravakar Dawadi ◽  
Sabina Khadka
Keyword(s):  
Cervical Cancer ◽  
Confidence Interval ◽  
Care Center ◽  
Tertiary Care ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Tertiary Care Center ◽  
Cross Sectional ◽  
Female Population ◽  
Incidence And Mortality

Introduction: Cervical cancer is one of the most common cancer among the female population inNepal. The incidence and mortality rate due to cervical cancer is higher in developing countrieslike Nepal due to a lack of proper screening and early diagnosis. This study aims to find out theprevalence of cervical cancer among cervical biopsies in a tertiary care center. Methods: A descriptive cross-sectional study was conducted among the hospital records of cervicalbiopsies from the department of pathology of Shree Birendra Hospital from 1st May 2018 to 30thApril 2019. Ethical approval was taken from the Institutional Review Committee in February 2020.This study was conducted among 146 cervical biopsies by using convenience sampling method.Point estimate at 95% Confidence Interval was calculated along with frequency and proportion forbinary data. Data were analyzed using excel 2016 software. Results: The prevalence of cervical cancer among 146 cases included in our study is found to be6 (4.11%) at 95% Confidence Interval (0.90-7.32). Among those cases of cervical cancer, 4 (66.67%)were squamous cell carcinoma, 1 (16.67%) was adenocarcinoma, and 1 (16.67%) was of other type.Maximum cases of cervical cancer were prevalent among higher age groups. Conclusions: Cervical cancer-related morbidity and mortality are different in different parts ofthe world. It’s burden is primarily seen in developing countries where there is a lack of effectivescreening programs.

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