scholarly journals Patients’ case scenario as well as approaches and strategies adopted to manage COVID-19 pandemic at Aligarh Muslim University, Aligarh, India

2020 ◽  
Author(s):  
Syed Ziaur Rahman ◽  
Saif Khan
Keyword(s):  
Health Care Professionals ◽  
Disease Transmission ◽  
Recovery Rate ◽  
Tertiary Care ◽  
Medical Science ◽  
Transmission Curve ◽  
Corona Virus ◽  
Global Pandemic ◽  
Severe Acute Respiratory Infection ◽  
The University

Corona virus Disease 2019 (COVID-19) is a severe acute respiratory infection caused by corona virus-2 (SARS-CoV-2). It originated from Wuhan city of China in December 2019 and spread like a wild fire to the entire globe and was declared as global pandemic by WHO on March 11, 2020. With no available cure and vaccine, this disease has taken a mammoth toll on the human life; therefore, SMS (‘Social Distancing’, use of ‘Mask’ and regular hand washing with ‘Soap’) has emerged as a sole tool to prevent its spread. The Indian government declared the first lockdown from March 25th 2020 with subsequent second, third and fourth lockdowns up to 31st March 2020 to decrease the disease transmission and flatten the disease transmission curve. Aligarh Muslim University is one of the prestigious central and residential universities in India. It is located in Aligarh district adjoining national capital region. The university has an attached tertiary care ‘Jawaharlal Nehru Medical College Hospital’. This narrative review discusses the various steps and procedures taken up by the university and hospital administration, other functionaries, faculty members and doctors in tackling the serious pandemic until 22nd June 2020. The proactive role of administration, dedication and hard work of health care professionals and innovation of some academicians has given a new vista of opportunities to tackle this global health pandemic. The recovery rate of coronavirus patients at AMU hospital is recorded as 71.9%, which is much higher than national average recovery rate (56%). Thus, AMU model gives some positive insights to fight the current global pandemic. Bangladesh Journal of Medical Science Vol.19(0) 2020 p. S 28-S 35

scholarly journals Coughs, Colds and "Freshers' Flu" Survey in the University of Cambridge, 2007-2008

2021 ◽  
Author(s):  
Ken TD Eames ◽  
Maria L Tang ◽  
Edward M Hill ◽  
Michael M Tildesley ◽  
Jonathan M Read ◽  
...  
Keyword(s):  
Disease Transmission ◽  
Online Survey ◽  
Small Group Teaching ◽  
Infectious Disease Transmission ◽  
Respiratory Illnesses ◽  
University Of Cambridge ◽  
Global Pandemic ◽  
Social Settings ◽  
Close Proximity ◽  
The University

Universities provide many opportunities for the spread of infectious respiratory illnesses. Students are brought together into close proximity from all across the world and interact with one another in their accommodation, through lectures and small group teaching and in social settings. The COVID-19 global pandemic has highlighted the need for sufficient data to help determine which of these factors are important for infectious disease transmission in universities and hence control university morbidity as well as community spillover. We describe the data from a previously unpublished self-reported university survey of coughs, colds and flu-like symptoms collected in Cambridge, UK, during winter 2007-2008. The online survey collected information on symptoms and socio-demographic, academic and lifestyle factors. There were 1076 responses, 97% from University of Cambridge students (5.7% of the total university student population), 3% from staff and <1% from other participants, reporting onset of symptoms between September 2007 and March 2008. Undergraduates are seen to report symptoms earlier in the term than postgraduates; differences in reported date of symptoms are also seen between subjects and accommodation types, although these descriptive results could be confounded by survey biases. Despite the historic and exploratory nature of the study, this is one of few recent detailed datasets of flu-like infection in a university context and is especially valuable to share now to improve understanding of potential transmission dynamics in universities during the current COVID-19 pandemic.

scholarly journals Study of nutritional and immunization status in children 6 months to 3 years attending outpatient department at a tertiary care hospital in rural South Rajasthan, India

2018 ◽  
Vol 6 (1) ◽  
pp. 15
Author(s):  
Vivek Parasher ◽  
Gaurav Dadhich ◽  
Rahul Khatri ◽  
Mansi Sharma
Keyword(s):  
Breast Feeding ◽  
Health Care Professionals ◽  
Severe Acute Malnutrition ◽  
Tertiary Care ◽  
Medical Science ◽  
Acute Malnutrition ◽  
Care Hospital ◽  
Physical And Mental Health ◽  
Exclusive Breast Feeding ◽  
The Impact

Background: Good nutrition, particularly in the first three years of life, is important in establishing and maintaining a good foundation that has implications on a child’s future physical and mental health. The present study has been undertaken to study the “Impact of the nutritional and immunization services on the children between 6 months to 3 years,” with special emphasis to identify moderate acute malnutrition (MAM) and severe acute malnutrition (SAM) cases.Methods: This observational study was conducted from August 2017 to July 2018 in department of paediatrics at pacific institute of medical science included 400 cases age between 6 months to 3 years.Results: Incidence of SAM and MAM is 7.5% and 30.75 % respectively. Female predominance was seen in SAM and MAM i.e. 53.4% and 54.6% respectively. Significant association of under-nutrition was found with LBW (p<0.05), not giving exclusive breast feeding up to 6 months of life (p<0.05) and, Low socioeconomic status (p<0.001). Higher numbers of females were unvaccinated.Conclusions: Despite introduction of various national programs at different levels for improvement of maternal and child health, we still have significant number of children who are undernourished and unimmunized. Children are future of our nation and their health is of paramount importance. It can only be achieved with strong political will, active participation of community and by increase commitment of health care professionals. We need to start from birth, institutional delivery, exclusive breast feeding, immunization, and timely introduction of complementary feeds, marriages at appropriate age, proper antenatal visits and birth spacing. 

scholarly journals The Attitudes of Physiotherapy Students Toward Occupational Medicine

2016 ◽  
Vol 12 (36) ◽  
pp. 39 ◽  
Author(s):  
Henrrik Prendushi
Keyword(s):  
Health Care Professionals ◽  
Occupational Medicine ◽  
Demographic Data ◽  
Medical Science ◽  
General Character ◽  
Work Related ◽  
The People ◽  
Career Option ◽  
Level Of Knowledge ◽  
The University

Diseases and work-related injuries make an important part in the global burden of disease. These are studied, prevented and treated by occupational professionals as well as other health care professionals. Physiotherapists have an important role in rehabilitation of the people suffering from different workrelated injuries and diseases. Our study aims to know the attitudes of the students of Physiotherapy regarding the Occupational Medicine, in its general character, as well as their perceptions about the Albanian reality, the future of this medical science in Albania, and the relations with their profession. An anonymous questionnaire was distributed to the third year students of Physiotherapy at the University Luigj Gurakuqi in Shkodra, in their first lesson of Occupational Medicine. It consisted of 23 questions, some of them in the form of a 5 point Likert. The questionnaire was made in two parts: demographic data and the research data. The questionnaire was completed by 31 students. There is a good level of knowledge of foreign languages, 27 of them know English. The need to study the subject resulted in 3.90 points on a 5 point Likert. The degree of awareness of occupational medicine in Albania resulted in 2.03 points and the implementation of the laws in just 1.90 points, but more than 90% of the students affirm that there is an increased interest on occupational medicine during last 5 years in the country. They unanimously agree about the relationships between their profession and the occupational medicine. The majority of the students are interested about more training, and for more than one half it is a career option, too.

The First COVID-19 Mortality in Batu Pahat, Johor: Lesson Learnt

2021 ◽  
Author(s):  
Shu Ann Hon ◽  
Lian Thai Lee ◽  
Qin Jian Low
Keyword(s):  
Respiratory Failure ◽  
Interferon Beta ◽  
Distress Syndrome ◽  
Healthcare Services ◽  
Nasopharyngeal Swab ◽  
Mortality Risks ◽  
Corona Virus ◽  
Global Pandemic ◽  
Severe Acute Respiratory Infection ◽  
Risk Patients

COVID-19 had been declared as a global pandemic on 11 March 2020. This case report is about Severe Acute Respiratory Infection (SARI) due to COVID-19 (Corona Virus-19). A 68-yearold lady with underlying hypertension and congestive cardiac failure presented with fever and productive cough for 5 days duration. One week before her presentation, she had travelled to Kluang, Johor for a wedding gathering which was later found to have contributed to a cluster of COVID-19 cases. Otherwise, she denied any sick or known COVID-19 contact. Respiratory examination revealed left lower zonecrepitations. She was tachypnoeic on a high flow mask 15 L and hypotensive (BP 90/70 mm Hg) on arrival at the hospital. Chest radiograph showed bilateral asymmetrical consolidations. There was a presence of lymphopenia while her dengue serology result was negative. She was treated as SARI secondary to pneumonia with septic shock and required mechanical ventilation due to respiratory failure. Nasopharyngeal swab for SARS CoV-2 (Severe Acute Respiratory Syndrome Corona Virus-2) was taken as positive for COVID-19 on the third day of admission. Apart from supportive andintensive care measures, she was commenced on oral hydroxychloroquine, subcutaneous Interferon Beta and syrup lopinavir/ritonavir per local guidelines during that period. Unfortunately, she developed acute respiratory distress syndrome (ARDS) on day 3 of admission and passed away due to respiratory failure. Clinicians should pay attention to the COVID-19 critical disease profile and mortality risks. By identifying high-risk patients early, medical resources can be administered in an organized way and timely way to improve the efficacy of the healthcare services.

scholarly journals Perception of Health Care Professionals on Transplantation in the Treatment of COVID-19 Patients

2020 ◽  
Vol 1 (2) ◽  
pp. 11-15
Author(s):  
Bikash Sah Bikash Sah ◽  
Shivendra Jha ◽  
Ashok Ayer ◽  
Deebya Raj Mishra ◽  
B. N. Yadav
Keyword(s):  
Health Care ◽  
Lung Transplantation ◽  
Health Care Professionals ◽  
Virus Disease ◽  
Tertiary Care ◽  
Solid Organ Transplantation ◽  
Legal Issue ◽  
Solid Organ ◽  
Corona Virus ◽  
Perception Of Health

Corona virus disease 2019 (COVID-19) caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) has rapidly evolved as a pandemic with a challenge to the entire world for its management. Various modalities of treatment have been tried till date and when all the modalities failed then the only option that has been shown to be successful in some cases is lung transplantation. Decision for Solid-organ transplantation is not only made based upon its therapeutic requirement but also need to be supported by the law of land. In this regard, current Nepalese law is not with the provision for lung transplantation. Thus, in order to make the concerned authorities aware of it and also as a step toward the preparedness for COVID-19 pandemic, this research has been conducted with an aim to see the perception of health care professionals of tertiary care centre of eastern Nepal regarding the legal aspects of lung transplantation. Conclusion Outcome of this research has supported the therapeutic aspect of transplantation over its legal issue in the emergency conditions like COVID-19 Pandemic.

Immunophenotyping and cytogenetic profile of children with acute lymphoblastic leukemia: A study from a tertiary care center from Kashmir.

JMS SKIMS ◽  
2020 ◽  
Vol 23 (2) ◽  
Author(s):  
Faisal R Guru ◽  
Nisar Ahmad Syed ◽  
Shumail Bashir ◽  
Sanudev Sadanandan Vp ◽  
Hashim Kunju Ismail ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
Cytogenetic Study ◽  
Lymphoblastic Leukemia ◽  
Tertiary Care ◽  
Medical Science ◽  
Fish Analysis ◽  
Jammu And Kashmir ◽  
Mll Gene ◽  
Cytogenetic Profile ◽  
Study Participants

Background The complete cytogenetic and immunophenotyping data in children suffering from acute lymphoblastic leukemia (ALL) in Jammu and Kashmir is scarce. To bridge this knowledge gap the present study proposes to evaluate the immunophenotype and cytogenetic profile of pediatric ALL patients treated in our hospital. Material and methods This hospital-based observational study was conducted on 180 pediatric patients aged between 1  to 18 years who had visited the Paediatric unit of the  Department of Medical Oncology at Sher-I -Kashmir Institute of Medical Science, Srinagar ,Jammu and Kashmir between the January 2015 to December 2019. Result Among the study participants, 57.8% were male and 42.2% were female with a mean age of 9.24 years and median of 8 Years. Among the participants, 57.2% were below 10 years of age and 42.8% were above 10years of age. CNS disease was reported in 7.8%  of the study participants.  63.3% patients  had a TLC count of less than 20000. Immunophenotyping data revealed pre-B ALL in 77.8% of children. Cytogenetic study was conducted on 153 patients among them 74.4% had a normal karyotype, 7.2% s had hyperdiploidy and 3.3% had hypodiploidy. The FISH analysis showed that 23.3% of study participants were positive for the TEL-AML study, 11.1% were positive for BCR-ABL analysis and 4.4% of participants were positive for MLL gene analysis. The overall survival in the study population was 78.9% among the study participants. Only the MLL gene rearrangement analysis showed a statistically significant correlation with the survival analysis (P<0.5). Conclusion In summary, the present study reported the complete cytogenetic and immunophenotyping profile of the children suffering from acute lymphoblastic leukemia in Jammu and Kashmir.

Unique nCoV-2019 (COVID 19) spike glycoprotein processing by host protease: Analysis and Implication on infection

2020 ◽  
Vol 17 ◽  
Author(s):  
Ajoy Basak ◽  
Sarmistha Basak
Keyword(s):  
World Health ◽  
Spike Glycoprotein ◽  
Binding Domains ◽  
Corona Virus ◽  
Global Pandemic ◽  
High Infection ◽  
Crucial Information ◽  
Glycoprotein Processing ◽  
Health Organization ◽  
Host Reservoir

: The current global pandemic outbreak of a novel type of corona virus termed by World Health Organization as COVID-19 became an grave concern and worry to human health and world economy. Intense research efforts are now underway worldwide to combat and prevent the spread of this deadly disease. This zoonotic virus, a native to bat population is most likely transmitted to human via a host reservoir. Due to its close similarity to previously known SARS CoV (Severe Acute Respiratory Syndrome Corona Virus) of 2002 and related MERS CoV (Middle East Respiratory Syndrome Corona Virus) of 2012, it is also known as SARS CoV2. But unlike them it is far too infectious, virulent and lethal. Among its various proteins, the surface spike glycoprotein “S” has drawn significant attention because of its implication in viral recognition and host-virus fusion process. A detail comparative analysis of “S” proteins of SARS CoV (now called SARS CoV1), SARS CoV2 (COVID-19) and MERS CoV based on structure, sequence alignment, host cleavage sites, receptor binding domains, potential glycosylation and Cys-disulphide bridge locations has been performed. It revealed some key features and variations that may elucidate the high infection and virulence character of COVID-19. Moreover this crucial information may become useful in our quest for COVID-19 therapeutics and vaccines.

Coexistence of Metallo Beta Lactamase Resistant Gene Variants Among Clinical Isolates in Tertiary Care Hospital

2021 ◽  
Vol 18 (4) ◽  
pp. 429-436
Author(s):  
Santhiya K. ◽  
Jayanthi S. ◽  
Ananthasubramanian M. ◽  
Appalaraju B.
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Medical Science ◽  
Geographical Location ◽  
Carbapenem Resistance ◽  
Clinical Isolates ◽  
Care Hospital ◽  
Detection Rates ◽  
Carbapenem Resistant ◽  
Global Threat

Background: Carbapenem-resistant Enterobacteriaceae (CRE) has emerged as a global threat with mortality risk ranging from 48%-71% worldwide. The emergence of MBL resistance is threatening as carbapenem is one of the last line antibiotics. A total 24 variants of NDM resistance raises a concern to the clinicians and epidemiologists worldwide. Objective: The study aims at identifying MBL resistance (NDM, IMP, VIM, GIM, SPM, and SIM) and its coexistence in clinical isolates in a single tertiary care center. Methodology: Forty five clinical isolates characterized phenotypically for Carbapenem resistance obtained from PSG Institute of Medical Science and Research (PSG IMSR), Coimbatore, between February to March 2018 were taken for analysis. Result: Out of the 45 Clinical isolates, 38 isolates (84%) were detected as MBL carriers. VIM, NDM, GIM, and SPM were the predominant resistance genes, with detection rates of 48.8%, 28.8%, 24.4%, and 22.2% respectively. Fifteen isolates were observed to harbor more than one MBL gene in coexistence. Two isolates - U42 and R714 (K. pneumoniae) were found to harbor all 5 MBL variants in combination. Conclusion: 33% of clinical isolates harboring multiple MBL variants is a concern in clinical settings. The presence of SPM and GIM gene amongst isolates in this geographical location within India is an indicator demanding continuous monitoring of these resistance determinants.

scholarly journals Knowledge, attitude and perceptions about Crimean Congo Haemorrhagic Fever (CCHF) among occupationally high-risk healthcare professionals of Pakistan

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ali Ahmed ◽  
Muhammad Saqlain ◽  
Maria Tanveer ◽  
Azhar Hussain Tahir ◽  
Fakhar Ud-Din ◽  
...  
Keyword(s):  
At Risk ◽  
Health Care Professionals ◽  
Work Experience ◽  
Tertiary Care ◽  
Nosocomial Transmission ◽  
Haemorrhagic Fever ◽  
Sources Of Information ◽  
Validated Questionnaire ◽  
Low Middle Income Countries ◽  
Crimean Congo Haemorrhagic Fever

Abstract Background Crimean Congo Haemorrhagic Fever (CCHF), a tropically neglected infectious disease caused by Nairovirus, is endemic in low middle-income countries like Pakistan. Emergency health care professionals (HCPs) are at risk of contracting nosocomial transmission of CCHF. We, therefore, aim to analyze the knowledge, attitudes, and perceptions (KAP) of at-risk physicians, nurses, and pharmacists in Pakistan and the factors associated with good KAP. Method A validated questionnaire (Cronbach’s alpha 0.71) was used to collect data from HCPs in two CCHF endemic metropolitan cities of Pakistan by employing a cross-sectional study design. For data analysis percentages, chi-square test and Spearman correlation were applied by using SPSS version 22. Results Of the 478 participants, 56% (n = 268) were physicians, 37.4% (n = 179) were nurses, and 6.5% (n = 31) were pharmacists. The proportion of HCPs with good knowledge, attitude, and perception scores was 54.3%, 81, and 69%, respectively. Being a physician, having more work experience, having a higher age, working in tertiary care settings, were key factors for higher knowledge (p < 0.001). The correlation coefficient showed significant positive correlation between attitude- perception (r = 0.560, p < 0.001). Conclusion We have observed average knowledge of HCPs. Therefore, we recommend time to time education campaigns and workshops in highly endemic CCHF regions to be launched by health ministries and HCPs, in particular nurses, encouraged to follow authentic academic sources of information to prevent nosocomial transmission.

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