Clinical and orthopedic examination of loose cows

2020 ◽  
pp. 14-17
Author(s):  
Aleksandr S. Krasnoperov ◽  
◽  
Aleksandr I. Belousov ◽  
Larisa V. Khalturina ◽  
Sergey V. Malkov ◽  
...  
Keyword(s):  
Blood Serum ◽  
Musculoskeletal System ◽  
Dry Matter ◽  
Metabolic Disorders ◽  
Liver Enzymes ◽  
Biochemical Study ◽  
Clinical Signs ◽  
Metabolic Characteristics ◽  
Animal Feeding ◽  
Agricultural Organization

The results of clinical and orthopedic examination of highly productive loose cows in the agricultural organization of Sverdlovsk region are presented in the article. Due to the high percentage of pathology of the musculoskeletal system in animals, this farm was selected. As a result of the study, violations of veterinary sanitary norms of maintenance and technological violations in animal feeding were found. On average, more than 40.0% of animals recorded clinical signs of pathology of the musculoskeletal system. Biochemical studies of urine and blood serum were performed to determine the metabolic characteristics of the blood of animals with orthopedic pathology. Hypostenuria was established in 41.7% of the examined cows according to the results of a biochemical study of urine. This indicates a lack of the required level of dry matter consumption. In 31.3% of cows, manifestations of metabolic disorders were recorded (a decrease in total protein and albumin, an increase in urea in the blood serum). In 25.0% of animals revealed the presence of intoxication syndrome - an increase in the activity of indicator liver enzymes (aspartate aminotransferase and glutamate dehydrogenase). Signs of development of osteodystrophic processes (a decrease in total calcium with an increase in alkaline phosphatase activity) were noted in more than 30.0% of cows.

Assessment of the quality of life in the treatment approaches of patients with the comorbid course of arterial hypertension and metabolic disorders aimed at reducing cardiovascular risk

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
V Zlatkina ◽  
V Shkapo ◽  
A Nesen ◽  
T Starchenko
Keyword(s):  
Quality Of Life ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Arterial Hypertension ◽  
Metabolic Disorders ◽  
Clinical Signs ◽  
Blood Analysis ◽  
Sf 36 ◽  
Artery Disease

Abstract Funding Acknowledgements Type of funding sources: None. Introduction. Cardiovascular diseases (CVD) remain the leading cause of premature death worldwide. According to epidemiological studies CVD prevention is highly effective. A 50% reduction in mortality from coronary artery disease (CAD) is associated with exposure to risk factors and only 40% with improved treatment. Purpose.  To assess the quality of life (QOL) in patients with arterial hypertension (AH) and metabolic disorders, to establish its impact on therapy effectiveness. We examined 280 patients with AH and comorbidity - 171 women and 109 men aged 45-75 years. Along with AH, all patients had comorbidities: 72.6 % suffered from coronary artery disease (CAD), 10.5% after myocardial infarction (MI), 35 % had clinical signs of heart failure (HF), 22, 1% - type 2 diabetes mellitus (t2DM), 27.4% - chronic kidney disease (CKD). Methods. Anthropometry, blood pressure (BP) measurement, immunoassay (C-reactive protein), biochemical blood analysis (lipid, carbohydrate metabolism parameters, QOL determination (questionnaire Sf-36). Results. In patients with comorbidity of pathologies (presence of AH, t2DM, CKD, CAD, obesity), there was a decrease in assessments in almost all indicators of QOL, and especially significant limitations in the performance of daily activities due to both physical and mental state. Conclusion. The degree of AH in patients with t2DM decreased QOL of physical activity, role-physical functioning, pain and general health, reflecting physical health, as well as mental health, including vitality, social activity, role emotional functioning. T2DM in patients with AH significantly worsens QOL of this category of patients as in physical component summary and mental component summary. The indicators of QOL are significantly affected by the duration of t2DM, as well as the degree of compensation. Achievement of the target BP levels in patients with AH with t2DM shows an improvement in a number of QOL parameters and makes it possible to recommend the Sf-36 questionnaire as a criterion for the effectiveness of the therapy.

Ergonomic risk factors for the development of disorders of the musculoskeletal system in adolescents

2020 ◽  
pp. 37-46
Author(s):  
Tamara Anatol'evna Novikova ◽  
Vladimir Nikolaevich Dolich ◽  
Nanaliya Evgen'evna Komleva ◽  
Vyacheslav Alexandrovich Medentsov ◽  
Anatoliy Nikolaevich Mikerov
Keyword(s):  
Risk Factors ◽  
Information And Communication Technologies ◽  
Musculoskeletal System ◽  
Clinical Signs ◽  
Educational Process ◽  
Teaching Aids ◽  
Information And Communication ◽  
Electronic Computers ◽  
Ergonomic Risk Factors ◽  
Ergonomic Risk

Prevention of health disorders and sexual development of society is a priority area of hygiene and preventive medicine. The introduction of information and communication technologies into the educational process is a new risk factor for the development of disorders of the musculoskeletal system in adolescents. Purpose of the study: assessment of ergonomic risk factors for the development of disorders of the musculoskeletal system in adolescents using personal electronic computers as teaching aids. Objects of research: sanitary-hygienic and ergonomic factors of learning conditions with the use of personal computers and the state of the musculoskeletal system of college students. Research in accordance with the requirements of bioethics, after signing the informed consent and their parents. The hygienic factors of the learning environment and the ergonomic characteristics of furniture (tables, work chairs) in computer science classes of the Saratov college were studied. Their assessment is given for compliance with sanitary and epidemiological requirements and anthropometric indicators of students. A questionnaire survey and physical examination of 308 adolescents were carried out to identify complaints and assess the condition of the musculoskeletal system. It has been established that the organization and ergonomic characteristics of workplaces equipped with electronic computers fully comply with hygienic and ergonomic requirements. This is the cause of postural disorders and the development of disorders of the condition of the musculoskeletal system of students. A high prevalence of clinical signs of disorders of the musculoskeletal system among adolescents was revealed. It has been established that compliance with ergonomic requirements in the organization of workplaces when using personal electronic computers is a prerequisite for the primary prevention of disorders of the musculoskeletal system in adolescents. To solve this problem, first of all, it is necessary to provide educational institutions with modern furniture that meets ergonomic requirements.

scholarly journals Significance of asymptomatic hyperuricemia in ankylosing spondylitis

2021 ◽  
Vol 15 (3) ◽  
pp. 57-61
Author(s):  
R. M. Balabanova ◽  
E. V. Ilyinykh ◽  
M. V. Podryadnova ◽  
S. I. Glukhova ◽  
M. M. Urumova
Keyword(s):  
Rheumatoid Arthritis ◽  
Ankylosing Spondylitis ◽  
Blood Serum ◽  
Disease Activity ◽  
Filtration Rate ◽  
Metabolic Disorders ◽  
Clinical Manifestations ◽  
The Past ◽  
The Metabolic Syndrome ◽  
Medical Histories

Over the past decades, there has been an increase in the incidence of asymptomatic hyperuricemia (AHU), which includes an increased level (>360 μmol/L) of uric acid (UA) in the blood serum of patients with no clinical manifestations of gout. AHU is reported in various rheumatic diseases, mainly in osteoarthritis, in which AHU is one of the manifestations of the metabolic syndrome. There is relationship between AHU and pulmonary hypertension in systemic sclerosis, arterial hypertension (AH) in men with seronegative rheumatoid arthritis, extensive cutaneous psoriasis and metabolic disorders in psoriatic arthritis. There are almost no data on AHU in ankylosing spondylitis (AS), which served objective for this work.Objective: to assess the association of AHU with AS duration and activity and the presence of comorbid diseases.Patients and methods. A retrospective analysis of 48 medical histories of patients with diagnosed AS, who were treated in V.A. Nasonova Research Institute of Rheumatology from 2015 to 2019 years, whose serum UA level was >360 μmol/L.Results and discussion. More than half of patients with AS and AHU were overweight, 21% were obese. AH was diagnosed in 43.7% of patients. Stage II–III chronic kidney disease was detected in 16.7% of patients, urolithiasis – in 18.8%. 4 (8.3%) patients had diabetes mellitus. The serum UA level in patients with AS was 422.0 ± 61.6 μmol/L. In patients with AS, an association between AHU and age, duration and disease activity was noted. There was no statistically significant rela- tionship between HG and blood glucose, cholesterol, creatinine levels, body mass index. Correlation analysis revealed a statistically significant relationship between the glomerular filtration rate (GFR) and the age of patients (r=-0.54, p<0.001), the duration of the disease (r=-0.40, p<0.05), cholesterol level (r=-0.48, p=0.01), UA level (r=-0.45, p=0.03) and blood pressure (r=-0.54, p<0.001). There was no association between disease activity and GFR (p>0.05).Conclusion. In AS, an association between an increased level of UA in the blood serum and the duration and activity of the disease, and patient's age, was established.

scholarly journals BIOCHEMICAL EVALUATION OF CHRONIC CONSUMPTION OF MONOSODIUM GLUTAMATE ON LIVER OF WISTAR ALBINO RATS

2021 ◽  
pp. 99-102
Author(s):  
SURENDRA BABU THANGACHI ◽  
VARSHA SRIRAM MOKHASI ◽  
SHABINA KOMATH CHENOLY
Keyword(s):  
Blood Serum ◽  
Total Cholesterol ◽  
Total Bilirubin ◽  
Liver Enzymes ◽  
Monosodium Glutamate ◽  
Density Lipoprotein ◽  
Lipid Profiles ◽  
Albino Rats ◽  
High Dose ◽  
Wistar Albino Rats

Objective: The objective of this study was to determine if there were any harmful effects of monosodium glutamate (MSG) on the liver of Wistar albino rats chronically at three different doses, namely, low, mid, and high doses equivalent to human consumption doses in developing countries. Methods: The Wistar albino rats (n=24) were divided into four groups, namely control, Low dose MSG (180 mg/kg), Mid dose MSG (360 mg/kg), and High dose MSG (720 mg/kg). At the end of the experimental period (120 days), animal blood was collected retro-orbitally to analyze the liver enzymes such as aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), Total protein, Albumin, and Total Bilirubin in blood serum. Lipid profiles, namely, Triglycerides, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and Total cholesterol were subjected to analysis using blood serum. Results: Significant increase (p<0.05) in AST, ALT, ALP, and total bilirubin in serum of MSG induced low, mid, and high dose groups when compared to control group were recorded. There was a significant increase (p<0.05) in LDL, decrease in HDL, increase in total cholesterol and triglycerides of MSG-induced animal groups. Conclusion: The effects of MSG on serum liver enzymes and lipid profiles in this present animal study were not severely alarming even though the dosage was chronic which opens further discussion on the controversies revolving around MSG.

scholarly journals Proposal of an Algorithm to Early Detect Attenuated Type I Mucopolysaccharidosis (MPS Ia) among Children with Growth Abnormalities

Medicina ◽  
2022 ◽  
Vol 58 (1) ◽  
pp. 97
Author(s):  
Federico Baronio ◽  
Stefano Zucchini ◽  
Francesco Zulian ◽  
Mariacarolina Salerno ◽  
Rossella Parini ◽  
...  
Keyword(s):  
Short Stature ◽  
Metabolic Disorders ◽  
Clinical Presentation ◽  
Diagnostic Delay ◽  
Clinical Signs ◽  
Clinical Approach ◽  
Type I ◽  
Mucopolysaccharidosis Type I ◽  
Stunted Growth ◽  
Growth Abnormalities

Background and Objectives: Diagnostic delay is common in attenuated Mucopolysaccharidosis Type I (MPS Ia) due to the rarity of the disease and the variability of clinical presentation. Short stature and impaired growth velocity are frequent findings in MPS Ia, but they rarely raise suspicion as paediatric endocrinologists are generally poorly trained to detect earlier and milder clinical signs of this condition. Materials and Methods: Following a consensus-based methodology, a multidisciplinary panel including paediatric endocrinologists, paediatricians with expertise in metabolic disorders, radiologists, and rheumatologists shared their experience on a possible clinical approach to the diagnosis of MPS Ia in children with short stature or stunted growth. Results: The result was the formation of an algorithm that illustrates how to raise the suspicion of MPS Ia in a patient older than 5 years with short stature and suggestive clinical signs. Conclusion: The proposed algorithm may represent a useful tool to improve the awareness of paediatric endocrinologists and reduce the diagnostic delay for patients with MPS Ia.

scholarly journals Study of haematological, biochemical profile and clinical presentation in dengue positive patients: 82 cases

2018 ◽  
Vol 6 (6) ◽  
pp. 2099
Author(s):  
Mubin I. Patel ◽  
Abhishek Patel ◽  
Avani Patel ◽  
Sharmistha Patel ◽  
Suresh Padsala
Keyword(s):  
Dengue Fever ◽  
Clinical Presentation ◽  
Liver Enzymes ◽  
Neglected Tropical Diseases ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Biochemical Profile ◽  
Igg Antibody ◽  
Aedes Mosquitoes ◽  
Clinical Signs And Symptoms

Background: Dengue Fever (DF) is a self-limiting disease caused by arbovirus and transmitted by Aedes mosquitoes (Aedes aegypti and Aedes albopictus). It is one of the 17 neglected tropical diseases by WHO. Diagnosis of dengue depends mainly on the detection of IgM and IgG antibody, and NS1 antigen.Methods: The study was carried out in Department of Pathology, affiliated with a government hospital. It includes 82 dengue patients, admitted from August 2015 to August 2016. Haematological, biochemical profile, clinical signs and symptoms were recorded. The Tourniquet test was performed in all the patients on admission. Grading of dengue: DF/DHFI/DHFII/DHFIII/DHFIV. Grade III and IV were collectively called as Dengue Shock Syndrome.Results: Total 82 Dengue positive cases were studied, 52 (63%) were males and 30 (37%) were females. 24 (29%) patients were recorded in September 22 (27%) in October 19 (23%) in August. 12 (14.60%) had positive tourniquet test. Thrombocytopenia was present in 86.5 % patients. Majority cases were of classical dengue fever 51 (62.20%), 14 (17.07%) were of DHF I, 12 (14.63%) were of DHF II, 3 (3.66%) were of DHF III and 2 (2.44%) were of DHF IV.Conclusions: It is very important to correlate clinical examination with haematological and biochemical profile in dengue patients. Hematocrit value, leucopenia, thrombocytopenia, raised liver enzymes is very important to monitor dengue cases in their initial stages and thus facilitate early treatment. This would minimize morbidity and mortality arising out of serious complications of dengue fever.

scholarly journals Clinical Signs and Laboratory Parameters as Predictors of Mortality among Hospitalized Human Immunodeficiency Virus-Infected Adult Patients at Tertiary Hospital in Surabaya

2021 ◽  
Vol 9 (B) ◽  
pp. 497-502
Author(s):  
Rentha Monica Simamora ◽  
Muhammad Vitanata Arfijanto ◽  
Musofa Rusli ◽  
Budi Utomo ◽  
Cennikon Pakpahan ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Multivariate Analysis ◽  
Platelet Count ◽  
Liver Enzymes ◽  
Clinical Signs ◽  
Tertiary Hospital ◽  
Bivariate Analysis ◽  
Elevated Liver Enzymes ◽  
Immunodeficiency Virus ◽  
Hiv Aids

BACKGROUND: The morbidity and mortality rates due to human immunodeficiency virus (HIV) infection are still high despite various and advanced efforts in the management given for HIV/AIDS patients. AIM: This study proposed that clinical signs and laboratory parameters could be expected to predict the patient’s mortality. METHODS: This retrospective study was done by collecting 408 medical records of adult HIV/AIDS inpatients at a tertiary hospital in Surabaya from January 1, 2017, to December 31, 2019. Bivariate analysis using Chi-square test was carried out on nine variables, which were Glasgow Coma Scale (GCS) <15, hypotension, PaO2/FiO2 <400 mmHg, elevated liver enzymes, hemoglobin levels <10 mg/dl, platelet count <150,000/mm3, eGFR <60 ml/min/1.73 m2, albumin levels <3.5 mg/dl, and body mass index (BMI) <18.5 kg/m2. Variables which met the criteria would be included in the multivariate analysis using logistic regression. RESULTS: Based on bivariate analysis, mortality was found to be significantly associated with GCS <15, hypotension, PaO2/FiO2, elevated liver enzymes, platelet count <100,000 mm3, eGFR <60 ml/1.73kg/m2, albumin levels <3.5 mgdl, and BMI <18.5 kg/m2. However, based on multivariate analysis, there were five variables which were found to be able to independently predict the patients’ mortality, those were GCS <15 (OR 11.625), hypotension (OR 6.062), PaO2/FiO2< 400 mmHg (OR 7.794), eGFR <60 ml/min/1.73 m2 (OR 2.646), and albumin levels <3.5 mg/dl (OR 4.091). CONCLUSION: GCS <15, hypotension, PaO2/FiO2 <400 mmHg, eGFR <60 ml/1.73g/m2, and albumin levels <3.5 mg/dl were found as the independent risk factors which could predict the hospitalized HIV/AIDS patients’ mortality.

scholarly journals Effect of the first and second postpartum partial milking on blood serum calcium concentration in dairy cows

2014 ◽  
Vol 59 (No. 3) ◽  
pp. 128-133
Author(s):  
E.G. Salgado-Hernández ◽  
A. Aparicio-Cecilio ◽  
F.H. Velásquez-Forero ◽  
D.A. Castillo-Mata
Keyword(s):  
Blood Serum ◽  
Dairy Cows ◽  
Serum Calcium ◽  
Metabolic Disorders ◽  
Calcium Concentration ◽  
Atomic Absorption Spectrophotometry ◽  
Serum Calcium Concentration ◽  
Group 2 ◽  
Group 1

Parturient paresis and subclinical hypocalcemia are frequent metabolic disorders in dairy cows postpartum. The aim of this study was to determine the effect of postpartum partial milking in the first two milkings on blood serum calcium concentration in dairy cows. Twenty multiparous Holstein dairy cows were randomized into two groups. Cows of group 1 (n = 10) were partially milked at the first and second milking postpartum. Cows of group 2 (n = 10) were completely milked. Blood samples were collected from all animals 5&ndash;7 days before calving, within 30 min after calving, and 4, 8, 12, 16, 20, 24, 28, and 32 h after calving for determination of serum calcium (Ca), phosphorus (P), and magnesium (Mg) concentrations. Colostrum production was registered and sampled in the first and second milking. Concentration of Ca in colostrum was determined by atomic absorption spectrophotometry. Serum Ca and P concentrations decreased in both groups after parturition (P &lt; 0.05) and remained low during 32 h postpartum with no difference observed between groups (P &gt; 0.05). Serum concentrations of Mg were stable in all samples and no statistical difference was observed between groups (P &gt; 0.05). Colostrum production was higher in completely milked cows only in the first postpartum milking (P &lt; 0.05), but there was no difference between groups at the second milking. Total Ca secretion in colostrum was higher in the complete milking group at the first and second postpartum milking. Colostrum Ca secretion increased at the second milking with respect to the first one in both groups (P &lt; 0.05). There was no correlation between serum Ca and colostrum Ca (P &gt; 0.05). In this study, the partial milking of colostrum in the first and second milking postpartum did not prevent subclinical hypocalcemia in dairy cows. &nbsp;

Dry-matter intake and live-weight gain of cattle and sheep offered different grass varieties with and without clover

1969 ◽  
Vol 11 (1) ◽  
pp. 19-28 ◽  
Author(s):  
D. G. Miles ◽  
R. J. K. Walters ◽  
E. M. Evans
Keyword(s):  
Weight Gain ◽  
Feed Intake ◽  
Dry Matter ◽  
Live Weight ◽  
Red Clover ◽  
Dry Matter Intake ◽  
Live Weight Gain ◽  
Feeding Value ◽  
Feeding Trials ◽  
Animal Feeding

SUMMARYA series of animal feeding trials was designed to determine differences between grasses in dry-matter intake and animal live-weight gain, with a view to indicating better selection criteria for improving the feeding value of herbage.Wide differences were demonstrated in feed intake and live-weight gain between single-variety grass feeds at similar levels of digestibility.S.37 cocksfoot gave consistently good and S.51 timothy, consistently poor responses.Supplementation of grass feeds with red clover frequently resulted in marked improvement in feed intake and animal performance.

The effect of ammoniated and roasted barley on rumen pH, milk yield and milk composition of lactating dairy cows

2003 ◽  
Vol 2003 ◽  
pp. 107-107
Author(s):  
M. H. Fathi ◽  
A. Nikkhah
Keyword(s):  
Dairy Cows ◽  
Milk Yield ◽  
Milk Fat ◽  
Dry Matter ◽  
Metabolic Disorders ◽  
Milk Composition ◽  
Barley Grain ◽  
Nutrient Requirements ◽  
Rumen Ph ◽  
Lactating Dairy Cows

Cereal grains can provide the major source of energy in diets in order to meet the nutrient requirements of high producing dairy cows. However the amount of starch that can be included in the diets of dairy cows is limited particularly if starch is rapidly fermented such as barley starch. Reduction of feed intake, rumen pH, milk fat test, microbial growth and other metabolic disorders are expected if ruminally degradable starch is fed in amount that cant be efficiently metabolized by rumen microbs. Various techniques for processing barley grain have been developed to decrease the degradability of dry matter in rumen without reducing its extent of digestion. McNiven (1995) showed roasting of barley is more effective treatment. The objective of this experiment was to study of effects the roasting and ammoniation of barley grain on rumen pH, feces pH, milk yield and milk composition in dairy cows.

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