scholarly journals Novel Bioactive Glass-Modified Hybrid Composite Resin: Mechanical Properties, Biocompatibility, and Antibacterial and Remineralizing Activity

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiao Han ◽  
Yan Chen ◽  
Qian Jiang ◽  
Xin Liu ◽  
Yaming Chen
Keyword(s):  
Mechanical Properties ◽  
Bioactive Glass ◽  
Hybrid Composite ◽  
Composite Resin ◽  
Ph Value ◽  
Biological Properties ◽  
Composite Resins ◽  
Mass Fractions ◽  
Good Biocompatibility ◽  
Insight Into

Secondary caries seriously limits the lifetime of composite resin. However, integrating all desirable properties (i.e., mechanical, antibacterial, bioactivity, and biocompatibility) into one composite resin is still challenging. Herein, a novel bioactive glass (BAG)-modified hybrid composite resin has been successfully developed to simultaneously achieve excellent mechanical properties, good biocompatibility, and antibacterial and remineralizing capabilities. When the mass fractions of BAG particles were added from 8 to 23 wt %, the original mechanical properties of the composite resin, including flexural strength and compressive strength, were not obviously affected without compromising the degree of conversion. Although the BAG incorporation of mass fractions of 16 wt % to 23 wt % in composite resins reduced cell viability, the viability could be recovered to normal by adjusting the pH value. Moreover, the BAG-modified composite resins that were obtained showed good antibacterial effects against Streptococcus mutans and enhanced remineralizing activity on demineralized dentin surfaces with increasing incorporation of BAG particles. The possible mechanisms for antibacterial and remineralizing activity might be closely related to the release of bioactive ions (Ca2+, Si4+), suggesting that its antibacterial and biological properties can be controlled by modulating the amounts of bioactive ions. The capability to balance the mechanical properties, cytotoxicity, antibacterial activity, and bioactivity makes the BAG-modified composite resin a promising prospect for clinical application. Our findings provide insight into better design and intelligent fabrication of bioactive composite resins.

scholarly journals A New Generation of Electrospun Fibers Containing Bioactive Glass Particles for Wound Healing

Materials ◽  
2020 ◽  
Vol 13 (24) ◽  
pp. 5651
Author(s):  
Rachele Sergi ◽  
Valeria Cannillo ◽  
Aldo R. Boccaccini ◽  
Liliana Liverani
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Bioactive Glass ◽  
Flexible Structures ◽  
Biological Properties ◽  
Cellular Viability ◽  
Bioactive Glasses ◽  
Electrospinning Technique ◽  
Potential Applications ◽  
Biological Performance

Chitosan fibers blended with polyethylene oxide (CHIT_PEO) and crosslinked with genipin were fabricated by electrospinning technique. Subsequently, CHIT_PEO bioactive glass composite electrospun mats were fabricated with the aim to achieve flexible structures with adequate mechanical properties and improved biological performance respect to CHIT_PEO fibers, for potential applications in wound healing. Three different compositions of bioactive glasses (BG) were selected and investigated: 45S5 BG, a Sr and Mg containing bioactive glass (BGMS10) and a Zn-containing bioactive glass (BGMS_2Zn). Particulate BGs (particles size < 20 μm) were separately added to the starting CHIT_PEO solution before electrospinning. The two recently developed bioactive glasses (BGMS10 and BGMS_2Zn) showed very promising biological properties in terms of bioactivity and cellular viability; thus, such compositions were added for the first time to CHIT_PEO solution to fabricate composite electrospun mats. The incorporation of bioactive glass particles and their distribution into CHIT_PEO fibers were assessed by SEM and FTIR analyses. Furthermore, CHIT_PEO composite electrospun mats showed improved mechanical properties in terms of Young’s Modulus compared to neat CHIT_PEO fibers; on the contrary, the values of tensile strain at break (%) were comparable. Biological performance in terms of cellular viability was investigated by means of WST-8 assay and CHIT_PEO composite electrospun mats showed cytocompatibility and the desired cellular viability.

scholarly journals Effect of different finishing and polishing techniques on the surface roughness of microfilled, hybrid and packable composite resins

2005 ◽  
Vol 16 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Silvia Helena Barbosa ◽  
Régia Luzia Zanata ◽  
Maria Fidela de Lima Navarro ◽  
Osvaldo Benoni Nunes
Keyword(s):  
Surface Roughness ◽  
Aluminum Oxide ◽  
Hybrid Composite ◽  
Composite Resin ◽  
Complete Sequence ◽  
Composite Resins ◽  
Average Surface Roughness ◽  
Surface Smoothness ◽  
Average Surface ◽  
System Data

This study examined the average surface roughness (Ra, µm) of 2 microfilled (Durafill and Perfection), 1 hybrid (Filtek Z250) and 2 packable composite resins (Surefil and Fill Magic), before (baseline) and after eight different finishing and polishing treatments. The surface roughness was assessed using a profilometer. Ten specimens of each composite resin were randomly subjected to one of the following finishing/polishing techniques: A - carbide burs; B - fine/extrafine diamond burs; C - Sof-Lex aluminum oxide discs; D - Super-Snap aluminum oxide discs; E - rubber polishing points + fine/extrafine polishing pastes; F - diamond burs + rubber polishing points + fine/extrafine polishing pastes; G - diamond burs + Sof-Lex system; H - diamond burs + Super-Snap system. Data were analyzed using two-way ANOVA and Tukey's HSD test. Significant differences (p<0.05) were detected among both the resins and the finishing/polishing techniques. For all resins, the use of diamond burs resulted in the greatest surface roughness (Ra: 0.69 to 1.44 µm). The lowest Ra means were obtained for the specimens treated with Sof-Lex discs (Ra: 0.11 to 0.25 µm). The Ra values of Durafill were lower than those of Perfection and Filtek Z250, and these in turn had lower Ra than the packable composite resins. Overall, the smoothest surfaces were obtained with the use the complete sequence of Sof-Lex discs. In areas that could not be reached by the aluminum oxide discs, the carbide burs and the association between rubber points and polishing pastes produced satisfactory surface smoothness for the packable and hybrid composite resins, respectively.

scholarly journals THE EFFECT OF Musa acuminata AND Ocimum basilicum MIXED EXTRACTS TO THE SURFACE HARDNESS OF BIOACTIVE COMPOSITE RESIN

2020 ◽  
Vol 5 (2) ◽  
pp. 172
Author(s):  
Dewi Puspitasari ◽  
Maharani Laillyza Apriasari ◽  
Dewi Rahayu ◽  
Priyawan Rachmadi
Keyword(s):  
Mechanical Properties ◽  
Composite Resin ◽  
Surface Hardness ◽  
Ocimum Basilicum ◽  
Musa Acuminata ◽  
Dental Restoration ◽  
Composite Resins ◽  
Mixed Solution ◽  
Leaf Extracts ◽  
Banana Stem

ABSTRACTBackgrounds: The use of mouthwash daily may influence the mechanical properties of bioactive composite resin as a dental restoration, one of the mechanical properties is surface hardness. Herbal mouthwash can be used to minimize the side effect of mouthwash that contain alcohol. Mauli banana stem and basil leaf extracts can be produced into herbal mouthwash. Methods: Thirty specimens (10mm diameter x 2mm thick; n=5/group) bioactive composite resins were immersed in a mixed solution of Mauli banana and basil leaf extracts with concentration of 25%, 50%, 75 %%, 100%, the control group of chlorhexidine gluconate 0.2% and aquadest for 7 days in 37oC. Measurement of the surface hardness was using the Vickers Microhardness Tester with 100 gf load for 15 seconds. Results: One Way ANOVA and Post Hoc Bonferroni exhibited the significant differences (p <0.05) in hardness values between the specimens that immersed in the mixed solution Mauli banana and Basil leaf extracts, which in the concentration of 100% (4,49 ± 4,61 VHN) compared with 25% (38,20 ± 2,58 VHN), 50% (41,40 ± 3,84 VHN) and 75% concentration (40,40 ± 3,55 VHN). There was no siginificant difference (p >0.05) between specimens immersed in CHX, aquadest and the mixed solution of mauli banana and basil leaf extracts in all concentration. Conclusion: There is no change in bioactive composite resin surface hardness after immersed in the mixed solution of Mauli Banana stem (Musa acuminata) and Basil leaf (Ocimum basilicum) extracts.Keywords: Basil leaf extract, Bioactive resin, Mauli Banana stem extract, Surface hardness

scholarly journals Pengaruh kopi arabika terhadap perubahan warna resin komposit hybrid

e-GIGI ◽  
2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Style V. Sirang ◽  
P. S. Anindita ◽  
. Juliatri
Keyword(s):  
Hybrid Composite ◽  
Composite Resin ◽  
Composite Resins ◽  
Control Group ◽  
Control Group Design ◽  
Arabica Coffee ◽  
Group Design ◽  
Hybrid Type ◽  
Post Test ◽  
One Way Anova

Abstract: Composite resin is one of the restorations used in the field of dentistry due to its good esthetic property. To date, the most commonly used composite resin is the hybrid type. Its weakness is the nature of fluid absorbance that can change its color. This discoloration can caused inter alia by food and beverage consumption. Arabica coffee is mostly consumed by our society, however, it has deposit of chlorogenic acid that might cause discoloration. This study was aimed to assess the influence of arabica coffee to the discoloration of hybrid composite resins. This was a true experimental study with a pre test and post test only control group design. Total samples were 24 composite resins of hybrid type (diameter 5 mm and height 2 mm). Each treatment group consisted of 6 samples. The samples were divided into 4 treatment groups, as follows: 0 day, 3 days, 5 days, and 7 days of immersion in arabica coffee solution. The one-way anova test showed that the influence of arabica coffee solution to discoloration of composite resins was significant (p=0.00). Conclusion: There was a significant influence of the duration of immersion in arabica coffee to discoloration of hybrid composite resinsKeywords: resin composite, discoloration, arabica coffee Abstrak: Resin komposit merupakan salah satu bahan restorasi yang sering digunakan di bidang kedokteran gigi karena memiliki nilai estetik yang baik. Saat ini jenis resin komposit yang sering digunakan yaitu resin komposit tipe hybrid. Resin komposit memiliki kekurangan yaitu sifat absorbansi cairan yang dapat menyebabkan perubahan warna. Salah satu penyebab perubahan warna yaitu makanan dan minuman. Kopi arabika merupakan minuman yang sering dikonsumsi oleh masyarakat dan memiliki kandungan asam klorogenik yang dapat memengaruhi perubahan warna. Penelitian ini bertujuan untuk mengetahui pengaruh kopi arabika terhadap perubahan warna resin komposit hybrid. Jenis penelitian ialaj eksperimental murni dengan pre test dan post test only control group design. Jumlah sampel penelitian yaitu 24 resin komposit tipe hybrid dengan ukuran diameter 5 mm dan tinggi 2 mm, dibagi dalam tiga kelompok. Masing-masing kelompok perlakuan terdiri dari 6 sampel. Sampel dibagi menjadi 4 kelompok yaitu kelompok perlakuan 0 hari, 3 hari, 5 hari, dan 7 hari perendaman dalam larutan kopi arabika. Hasil analisis data dengan uji one way Anova menunjukkan adanya pengaruh kopi arabika terhadap perubahan warna resin komposit (p=0,00). Simpulan: Terdapat pengaruh bermakna dari lama perendaman dalam kopi arabika terhadap perubahan warna resin komposit hybrid. Kata kunci : resin komposit, perubahan warna, kopi arabika

scholarly journals Special Issue: Ti-Based Biomaterials: Synthesis, Properties and Applications

Materials ◽  
2020 ◽  
Vol 13 (7) ◽  
pp. 1696 ◽  
Author(s):  
Jarosław Jakubowicz
Keyword(s):  
Mechanical Properties ◽  
High Strength ◽  
Biological Properties ◽  
Optimum Combination ◽  
Special Issue ◽  
Metallic Biomaterials ◽  
Synthesis Properties ◽  
Recent Developments ◽  
Good Biocompatibility ◽  
Bone Structures

In the last half century, great attention has been paid to materials that can be used in the human body to prepare parts that replace failed bone structures. Of all materials, Ti-based materials are the most desirable, because they provide an optimum combination of mechanical, chemical and biological properties. The successful application of Ti biomaterials has been confirmed mainly in dentistry, orthopedics and traumatology. The Ti biomaterials provide high strength and a relatively low Young’s modulus. Titanium biocompatibility is practically the highest of all metallic biomaterials, however new solutions are being sought to continuous improve their biocompatibility and osseointegration. Thus, the chemical modification of Ti results in the formation of new alloys or composites, which provide new perspectives for Ti biomaterials applications. Great attention has also been paid to the formation of nanostructures in Ti-based biomaterials, which has leads to extremely good mechanical properties and very good biocompatibility. Additionally, the surface treatment applied to Ti-based biomaterials provides faster osseointegration and improve in many cases mechanical properties. The special issue “Ti-Based Biomaterials: Synthesis, Properties and Applications” has been proposed as a means to present recent developments in the field. The articles included in the special issue cover broad aspects of Ti-based biomaterials formation with respect to design theirs structure, mechanical and biological properties, as highlighted in this editorial.

scholarly journals Development of Chlorhexidine Loaded Halloysite Nanotube Based Experimental Resin Composite with Enhanced Physico-Mechanical and Biological Properties for Dental Applications

2020 ◽  
Vol 4 (2) ◽  
pp. 81 ◽  
Author(s):  
Tejas Barot ◽  
Deepak Rawtani ◽  
Pratik Kulkarni
Keyword(s):  
Mechanical Properties ◽  
Resin Composite ◽  
Biological Properties ◽  
Degree Of Conversion ◽  
Dental Composites ◽  
Resin Composites ◽  
Dental Resin ◽  
Dental Resin Composites ◽  
Mass Fractions ◽  
Nih 3T3

Objective: The objective of this study was to explore the effect of Chlorhexidine-loaded Halloysite nanotubes (HNT/CHX) fillers (diverse mass fractions from 1 to 10 wt.%) on physicochemical, morphological and biological properties of newly developed experimental dental resin composite, in order to compare with the properties of composites composed of conventional glass fillers. Methods: The dental resin composites were prepared by incorporating various proportions of HNT/CHX. Six different groups of specimens: control group and five groups composed of varied mass fractions of HNT/CHX (e.g., 1.0, 2.5, 5.0, 7.5 and 10 wt.%) as fillers in each group were fabricated. Mechanical properties of the composites were monitored, using UTM. The degree of conversion of dental resin composites and their depth of cure were also evaluated. Antimicrobial properties of dental composites were studied in vitro by applying agar diffusion test on strain Streptococcus mutans and cytotoxicity were studied using NIH-3T3 cell line. Results: The incorporation of varied mass fractions (1.0 to 5.0 wt.%) of HNT/CHX in dental resins composites enhanced mechanical properties considerably with significant antibacterial activity. The slight decrease in curing depth and degree of conversion values of composites indicates its durability. No cytotoxicity was noticed on NIH-3T3 cell lines. Significance: Consistent distribution of HNT/CHX as a filler into dental composites could substantially improve not only mechanical properties but also biological properties of dental composites.

scholarly journals A Study of 3D-Printable Reinforced Composite Resin: PMMA Modified with Silver Nanoparticles Loaded Cellulose Nanocrystal

Materials ◽  
2018 ◽  
Vol 11 (12) ◽  
pp. 2444 ◽  
Author(s):  
Shenggui Chen ◽  
Junzhong Yang ◽  
Yong-Guang Jia ◽  
Bingheng Lu ◽  
Li Ren
Keyword(s):  
Electron Microscopy ◽  
Mechanical Properties ◽  
Silver Nanoparticles ◽  
Composite Resin ◽  
Antibacterial Activities ◽  
Dental Restoration ◽  
Composite Resins ◽  
Resin Matrix ◽  
Homogeneous Distribution ◽  
Reinforced Composite

With the rapid application of light-curing 3D printing technology, the demand for high-performance polymer resins is increasing. Existing light-curable resins often have drawbacks limiting their clinical applications. This study aims to develop a new type of polymethyl methacrylate (PMMA) composite resins with enhanced mechanical properties, high antibacterial activities and excellent biocompatibilities. A series of reinforced composite resins were prepared by mechanically mixing PMMA with modified cellulose nanocrystals (CNCs), which were coated with polydopamine and decorated by silver nanoparticles (AgNPs) via Tollen reaction. The morphology of CNCs-Ag was observed by transmission electron microscopy and the formation of AgNPs on CNCs was confirmed by X-Ray photoelectron spectroscopy analyses. Functional groups in PMMA-CNCs-Ag composites were verified by Fourier Transform infrared spectroscopy (FTIR) spectroscopy. The mechanical assessment and scanning electron microscopy analysis suggested that the evenly distributed CNCs-AgNPs composite effectively improve mechanical properties of PMMA resin. Cytotoxicity assay and antibacterial activity tests indicated excellent biocompatibility and high antibacterial activities. Furthermore, PMMA with CNCs-AgNPs of 0.1 wt.% (PMMA-CNCs-AgNPs-0.1) possessed the most desirable mechanical properties owing to the homogeneous distribution of AgNPs throughout the resin matrix. This specific composite resin can be used as a functional dental restoration material with potential of other medical applications.

Effect of Preheating and Fatiguing on Mechanical Properties of Bulk-fill and Conventional Composite Resin

2019 ◽  
Vol 45 (4) ◽  
pp. 387-395
Author(s):  
AA Abdulmajeed ◽  
TE Donovan ◽  
R Cook ◽  
TA Sulaiman
Keyword(s):  
Mechanical Properties ◽  
Fracture Toughness ◽  
Tensile Strength ◽  
Elastic Modulus ◽  
Flexural Strength ◽  
Composite Resin ◽  
Statistical Significance ◽  
Composite Resins ◽  
Significant Difference ◽  
Diametral Tensile Strength

Clinical Relevance Bulk-fill composite resins may have comparable mechanical properties to conventional composite resin. Preheating does not reduce the mechanical properties of composite resins. SUMMARY Statement of Problem: Bulk-fill composite resins are increasingly used for direct restorations. Preheating high-viscosity versions of these composites has been advocated to increase flowability and adaptability. It is not known what changes preheating may cause on the mechanical properties of these composite resins. Moreover, the mechanical properties of these composites after mastication simulation is lacking. Purpose: The purpose of this study was to evaluate the effect of fatiguing and preheating on the mechanical properties of bulk-fill composite resin in comparison to its conventional counterpart. Methods and Materials: One hundred eighty specimens of Filtek One Bulk Fill Restorative (FOBR; Bulk-Fill, 3M ESPE) and Filtek Supreme Ultra (FSU; Conventional, 3M ESPE) were prepared for each of the following tests: fracture toughness (International Organization for Standardization, ISO 6872), diametral tensile strength (No. 27 of ANSI/ADA), flexural strength, and elastic modulus (ISO Standard 4049). Specimens in the preheated group were heated to 68°C for 10 minutes and in the fatiguing group were cyclically loaded and thermocycled for 600,000 cycles and then tested. Two-/one-way analysis of variance followed by Tukey Honest Significant Difference (HSD) post hoc test was used to analyze data for statistical significance (α=0.05). Results: Preheating and fatiguing had a significant effect on the properties of both FSU and FOBR. Fracture toughness increased for FOBR specimens when preheated and decreased when fatigued (p=0.016). FOBR had higher fracture toughness value than FSU. Diametral tensile strength decreased significantly after fatiguing for FSU (p=0.0001). FOBR had a lower diametral tensile strength baseline value compared with FSU (p=0.004). Fatiguing significantly reduced the flexural strength of both FSU and FOBR (p=0.011). Preheating had no effect on the flexural strength of either FSU or FOBR. Preheating and fatiguing significantly decreased the elastic modulus of both composite resins equally (p&gt;0.05). Conclusions: Preheating and fatiguing influenced the mechanical properties of composite resins. Both composites displayed similar mechanical properties. Preheating did not yield a major negative effect on their mechanical properties; the clinical implications are yet to be determined.

Size control and biological properties of monodispersed mesoporous bioactive glass sub-micron spheres

RSC Advances ◽  
2014 ◽  
Vol 4 (43) ◽  
pp. 22678-22687 ◽  
Author(s):  
Qing Hu ◽  
Yuli Li ◽  
Guohou Miao ◽  
Naru Zhao ◽  
Xiaofeng Chen
Keyword(s):  
Bioactive Glass ◽  
Sol Gel ◽  
Size Control ◽  
Biological Properties ◽  
Gel Method ◽  
Sol Gel Method ◽  
Good Biocompatibility ◽  
Controllable Size ◽  
Mesoporous Bioactive Glass

Monodispersed mesoporous bioactive glass sub-micron spheres with a controllable size and good biocompatibility were fabricated by an improved sol–gel method.

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