Close Association between Awareness of Teeth-Alignment Disorder and Systemic Disorders in Late Adolescence

Background: Oral diseases are associated with various systemic disorders. Our previous research revealed new insights into the close relationship between occlusal disorder (functional disorder) and systemic disorders (allergic rhinitis, asthma, and arrhythmia) in late adolescence. Here, we investigated whether there was an association between the awareness of teeth-alignment disorder (morphological disorder) and common systemic disorders. Subjects and Methods: We retrospectively reviewed the data of the mandatory medical questionnaire that is required for the freshman medical checkup in Japan. We collected the data of all students who completed the questionnaire between April 2017 and April 2019. The data were analyzed using the χ2 test, and a multivariate analysis was performed with a binomial logistic regression model. Results: The subjects were 8903 students aged 17–19 who had no awareness of occlusal disorder. The rate of awareness of teeth-alignment disorder was 20.43% (1819 of 8903 eligible subjects), and the aware students had significantly greater rates of gum bleeding (p < 0.001), pollinosis (n = 0.007), and atopic dermatitis (n = 0.042). The multivariate analysis revealed significant rates of gum bleeding (odds ratio (OR) 1.540, 95% confidence interval (CI): 1.386–1.711, p < 0.001), pollinosis (OR 1.197, 95% CI: 1.040–1.378, p = 0.012), and female gender (OR 1.141, 95% CI: 1.002–1.299, p = 0.046) among the students with awareness of teeth-alignment disorder. Conclusion: We identified close associations between the awareness of teeth-alignment disorder and both gum bleeding and pollinosis in a late-adolescent population. The systemic disorders that are targeted by teeth-alignment disorder were found to be different from those targeted by occlusal disorder.

Download Full-text

Awareness of Malocclusion Is Closely Associated with Allergic Rhinitis, Asthma, and Arrhythmia in Late Adolescents

Healthcare ◽

10.3390/healthcare8030209 ◽

2020 ◽

Vol 8 (3) ◽

pp. 209

Author(s):

Masanobu Abe ◽

Akihisa Mitani ◽

Atsushi Yao ◽

Liang Zong ◽

Kazuto Hoshi ◽

...

Keyword(s):

Allergic Rhinitis ◽

Multivariate Analysis ◽

Odds Ratio ◽

Periodontal Diseases ◽

Systemic Diseases ◽

Late Adolescents ◽

Late Adolescent ◽

Medical Checkup ◽

Adolescent Population ◽

Insight Into

Background: Oral infectious diseases are typified by dental caries and periodontal diseases and are known to be associated with various systemic diseases. However, clear associations between occlusal disorders and systemic diseases have not yet been established. We investigated the association between an awareness of malocclusion and common diseases in late adolescence. Methods: We retrospectively reviewed the data of mandatory medical questionnaires that are a legal requirement of the freshman medical checkup. We collected the data of all the students who completed the questionnaires between April 2017 and 2019. The data were analyzed using the χ2 test and multivariate analysis was performed with a binomial logistic regression model. Results: The subjects were 9098 students aged 17–19 (mean age 18.3 years). The rate of awareness of malocclusion was 2.14% (195 out of 9098 eligible subjects; 160 males and 35 females). These students had significantly greater rates of allergic rhinitis, asthma, and arrhythmia (p < 0.001). Multivariate analysis revealed significant rates of allergic rhinitis (odds ratio [OR] 2.184, 95% confidence interval [CI]: 1.468–3.250, p < 0.001), asthma (OR 1.843, 95%CI: 1.153–2.945, p = 0.011), and arrhythmia (OR 2.809, 95%CI: 1.083–7.288, p = 0.034) among students with an awareness of malocclusion. Conclusion: We identified close associations between an awareness of malocclusion and systemic diseases including allergic rhinitis, asthma, and arrhythmia in the late adolescent population. These results reinforce the associations between malocclusion and allergic rhinitis and asthma, as well as providing novel insight into the association of malocclusion and arrhythmia. However, further research is necessary to confirm the associations and explore the mechanisms underlying these associations.

Download Full-text

Relative Frequency and Risk Factors of COVID-19 Related Headache in a Sample of Egyptian Population: A Hospital-Based Study

Pain Medicine ◽

10.1093/pm/pnab020 ◽

2021 ◽

Author(s):

Mona Hussein ◽

Wael Fathy ◽

Ragaey A Eid ◽

Hoda M Abdel-Hamid ◽

Ahmed Yehia ◽

...

Keyword(s):

Multivariate Analysis ◽

Platelet Count ◽

Relative Frequency ◽

Clinical Laboratory ◽

Primary Headache ◽

Female Gender ◽

Imaging Data ◽

Laboratory Findings ◽

Neutrophil Lymphocyte Ratio ◽

The Impact

Abstract Objectives Headache is considered one of the most frequent neurological manifestations of coronavirus disease 2019 (COVID-19). This work aimed to identify the relative frequency of COVID-19-related headache and to clarify the impact of clinical, laboratory findings of COVID-19 infection on headache occurrence and its response to analgesics. Design Cross-sectional study. Setting Recovered COVID-19 patients. Subjects In total, 782 patients with a confirmed diagnosis of COVID-19 infection. Methods Clinical, laboratory, and imaging data were obtained from the hospital medical records. Regarding patients who developed COVID-19 related headache, a trained neurologist performed an analysis of headache and its response to analgesics. Results The relative frequency of COVID-19 related headache among our sample was 55.1% with 95% confidence interval (CI) (.516–.586) for the estimated population prevalence. Female gender, malignancy, primary headache, fever, dehydration, lower levels of hemoglobin and platelets and higher levels of neutrophil/lymphocyte ratio (NLR) and CRP were significantly associated with COVID-19 related headache. Multivariate analysis revealed that female gender, fever, dehydration, primary headache, high NLR, and decreased platelet count were independent predictors of headache occurrence. By evaluating headache response to analgesics, old age, diabetes, hypertension, primary headache, severe COVID-19, steroid intake, higher CRP and ferritin and lower hemoglobin levels were associated with poor response to analgesics. Multivariate analysis revealed that primary headache, steroids intake, moderate and severe COVID-19 were independent predictors of non-response to analgesics. Discussion Headache occurs in 55.1% of patients with COVID-19. Female gender, fever, dehydration, primary headache, high NLR, and decreased platelet count are considered independent predictors of COVID-19 related headache.

Download Full-text

Diving into the Subconscious of Women and Nature: Margaret Atwood’s Surfacing as an Ecofeminist Novel

SMART MOVES JOURNAL IJELLH ◽

10.24113/ijellh.v6i10.5100 ◽

2018 ◽

Vol 6 (10) ◽

pp. 12

Author(s):

Hyma Santhosh

Keyword(s):

Margaret Atwood ◽

Female Gender ◽

Worth Living ◽

The Novel ◽

Life Worth Living ◽

Female Community ◽

Close Relationship ◽

Rapid Industrialization ◽

Male Dominated ◽

Self Discovery

Woman and nature can be considered the best creations of god. Both together keep the earth alive and balanced through the process of creation. The male dominated practices have destroyed the nature as well as women. This paper deals with the different aspects of Eco-feminism through the novel Surfacing by Margaret Atwood. The narrator’s quest to the wilderness of Canada in search for her father which leads to a quest of self-discovery in the lap of nature becomes the major focus of this paper. The unknown protagonist becomes a representative of the entire female community. The realization that women are just an object to be conquered and violated by men is what leads to the ‘surfacing’ of the protagonist. In complete harmony with nature excluding clothes, language, food etc. the protagonist goes crazy which gives her more happiness that with her other relationships. The paper also tries to analyse the close relationship between women and nature and how the virgin nature and woman are destroyed by the invasion of the male community. Repressed gender roles, submissiveness, self-realization through nature and the challenges faced by women that are presented. The concept of women and nature as both victims of the male dominated society is also emphasized. This novel is the perfect literary example of an Eco-feminist work that portrays the destruction of women and nature even in the minutest episodes in the novel. Nature is a treasure-house of many myths that lay hidden in the beliefs, rights and rituals of the aboriginals which are passed from one generation to another. In the same manner women also are the sustainer's of many myths that the male society has made upon her. The mother i.e. both woman and nature is examined here.In a vast country like Canada,nature comprises to its majority through its wilderness.This wilderness hides many priceless virtues and knowledge that can be learnt only in complete harmony with nature.Surfacing is not just the journey of a woman but it is the quest that the female gender thrives for.This paper combines the theories of eco-criticism, eco-feminism and to analyse the novel Surfacing into a biological whole that merges nature, man and the beliefs of man that make existence meaningful and life worth living. In an era of rapid industrialization and materialism, it is necessary to go on a quest back to nature and learn how life was easier in the lap of nature. Great writers like Shakespeare,Chaucer and Wordsworth were able to carve out such master pieces only because of their relationship with the purest and virgin nature which is the greatest teacher for mankind of all times.

Download Full-text

Psychological Legacies of Intergenerational Trauma under South African Apartheid: Prenatal Stress Predicts Increased Psychiatric Morbidity during Late Adolescence and Early Adulthood in Soweto, South Africa

10.1101/2021.01.11.21249579 ◽

2021 ◽

Author(s):

Andrew Wooyoung Kim ◽

Rihlat Said Mohamed ◽

Shane A. Norris ◽

Linda M. Richter ◽

Christopher W. Kuzawa

Keyword(s):

Social Support ◽

Pregnant Women ◽

Prenatal Stress ◽

Psychiatric Morbidity ◽

Late Adolescence ◽

Sub Saharan Africa ◽

Psychiatric Disease ◽

Birth Cohort Study ◽

Late Adolescent ◽

Intergenerational Effects

ABSTRACTBackgroundSouth Africa’s rates of psychiatric morbidity are among the highest in sub-Saharan Africa and are foregrounded by the country’s long history of political violence during apartheid. Recent evidence suggests that maternal trauma during gestation may intergenerationally impact the developing fetus and elevate the future child’s risk for psychiatric disease. We aim to evaluate the intergenerational effects of prenatal stress experienced during apartheid on late adolescent psychiatric morbidity and also assess the potential ameliorative effects of prenatal social support.MethodParticipants (n = 1051) come from Birth-to-Twenty, a longitudinal birth cohort study in Soweto-Johannesburg, South Africa’s largest peri-urban township which was the epicenter of violent repression and resistance during the final years of the apartheid regime. Pregnant women were prospectively enrolled in 1990 and completed questionnaires assessing social experiences, and their children’s psychiatric morbidity were assessed at age 17-18.ResultsFull data were available from 304 mother-child pairs in 2007-8. Pregnant women who experienced worse traumatic stress in 1990 had children who exhibited greater psychiatric morbidity during late adolescence. This relationship was only significant, however, among children born to younger mothers and adolescents who experienced greater concurrent stress. Social support did not buffer the long-term impacts of prenatal stress on future psychiatric morbidity.ConclusionGreater prenatal stress predicted adverse psychiatric outcomes among children born to younger mothers and adolescents who experienced greater concurrent stress. Our findings suggest that prenatal stress may affect adolescent mental health, have stress-sensitizing effects, and represent possible intergenerational effects of trauma experienced under apartheid in this sample.

Download Full-text

Aggression In Adolescent Chakma Tribal Students As A Function Of Gender And Stage Of Development

Journal of Life and Earth Science ◽

10.3329/jles.v6i0.9722 ◽

1970 ◽

Vol 6 ◽

pp. 59-63

Author(s):

Rasel Ahmed

Keyword(s):

Data Collection ◽

Factorial Design ◽

Aggressive Behaviour ◽

Late Adolescence ◽

Early Adolescent ◽

Late Adolescent ◽

Adolescent Group ◽

Stage Of Development

Aggression behaviour in 160 adult Chakma tribal students was studied. The subjects were equally divided into boys and girls. Each category was again subdivided into early adolescent and late adolescent. Age of early adolescent group ranged from 11 to 14 years and late adolescent group ranged from 15 to 18 years. Thus, the study used a 2×2 factorial design representing two levels of gender (boy versus girl) and two levels of stage of development (early versus late adolescence). The measure of aggressive behaviour was administered on the sample for data collection. It was found that regardless of stage of development, boys expressed significantly higher rates of aggression than girls. Similarly, regardless of gender, respondents at early adolescent stage expressed significantly higher rates of aggression than the respondents at late adolescent stage. DOI: http://dx.doi.org/10.3329/jles.v6i0.9722 JLES 2011 6: 59-63

Download Full-text

Exercise-Induced Asthma Symptoms and Nighttime Asthma: Are They Similar to AHR?

Journal of Allergy ◽

10.1155/2009/378245 ◽

2009 ◽

Vol 2009 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

V. Backer ◽

L. M. Rasmussen

Keyword(s):

Multivariate Analysis ◽

Airway Inflammation ◽

Airway Hyperresponsiveness ◽

Close Association ◽

Asthma Symptoms ◽

Exercise Induced

Background. Asthma experienced during exercise and during the night is based on the presence of airway hyperresponsiveness (AHR). The aim of the present study was to examine whether AHR is a predictor of exercise-induced asthma (EIA) and nighttime symptoms. Material. We included 793 asthmatics subjects with symptoms and a positive asthma test. Results. Mean (SD) FEV1 was 93% (15), 71% had rhinitis, and 62% had atopy. Both EIA and nighttime symptoms were associated with AHR; however, when including other factors of importance in a multivariate analysis, logRDR was eliminated, whereas FEV1% pred (P<.001), smoking (P<.05), atopy (P<.001), sex (P<.001), and treatment (P<.01) were associated with having EIA while dyspnoea (P<.001), cough (P<.001), and eosinophils (P<.01) were associated with frequent night symptoms. The risk of having nighttime awakenings due to asthma was more than twofold higher among those with EIA symptoms than among those without symptoms (OR (CI95%) 2.77 (2.0–3.8) (P<.001)). In Conclusion. EIA and night symptoms are associated with AHR, but other factors of importance eliminated this close association. Night asthma is more closely associated with airway inflammation than AHR.

Download Full-text

Text messaging: one step forward for phone companies, one leap backward for adolescence

International Journal of Adolescent Medicine and Health ◽

10.1515/ijamh.2011.011 ◽

2011 ◽

Vol 23 (1) ◽

Cited By ~ 4

Author(s):

Vanessa LaBode

Keyword(s):

Text Messaging ◽

Late Adolescence ◽

Long Term Effects ◽

Late Adolescent ◽

Developmental Issues ◽

Social Settings ◽

Adolescent Groups ◽

Characteristic Features ◽

Developmental Characteristics ◽

Sexual Exploration

Abstract The increasing popularity of text messaging has made this mode of communication the preferred interaction portal for teens. Virtually every teenager has a cell phone with an unlimited text messaging plan. Text messaging easily facilitates communication between individuals without much interruption into daily life. After administering a survey to ten early adolescents and ten late adolescents, the effects of this technology are manifested across many developmental characteristics. Communication, responsibility, and relationships all seem to be negatively influenced by the use of text messaging. This pattern is seen in both early and late adolescent groups. Developmentally, different characteristic features categorize early and late adolescence, yet it seems the use of text messaging is propelling early adolescence forward by removing the consequences of awkward face-to-face interactions. This early onset of late adolescence results in having very young teens, 12 and 13 year olds, showing increased interest in romantic relationships and sexual exploration. The anxiety and uneasiness felt by early teens about speaking with others has led to deficits in the ability to communicate in social settings, which could prove troublesome later. This study looks at only a few developmental issues associated with text messaging use among teens. It would be relevant and appropriate to study other ways that text messaging affects our youth in addition to exploring the more long-term effects of using this technology.

Download Full-text

Evaluation of late adolescent pregnancies: Is late adolescence a risk factor for preterm labor?

The Journal of Maternal-Fetal & Neonatal Medicine ◽

10.1080/14767058.2017.1393799 ◽

2017 ◽

Vol 32 (5) ◽

pp. 851-856 ◽

Cited By ~ 2

Author(s):

Sunullah Soysal ◽

Abdullah Sarioz ◽

Gokce Anik Ilhan ◽

Ali Kocagoz ◽

Aylin Dizi ◽

...

Keyword(s):

Risk Factor ◽

Preterm Labor ◽

Late Adolescence ◽

Late Adolescent ◽

Adolescent Pregnancies

Download Full-text

Defining Parameters That Can Guide Public Cord Blood Units (CBUs) in Korea

Blood ◽

10.1182/blood.v126.23.3102.3102 ◽

2015 ◽

Vol 126 (23) ◽

pp. 3102-3102

Author(s):

Junglim Lee ◽

Byung-Su Kim ◽

Soon- Hi Jang ◽

Tai-Gyu KIM

Keyword(s):

Multivariate Analysis ◽

Cord Blood ◽

Umbilical Cord ◽

Conflicts Of Interest ◽

Univariate Analysis ◽

Female Gender ◽

Limiting Factor ◽

Study Cohort ◽

Normal Delivery ◽

Hematopoietic Stem

Abstract Background: It is well known that Total Nucleated Cell (TNC) and CD34 are the greatest limiting factor in the use of umbilical cord blood (UCB) for transplantation. To enhance high UCB quality, it is important that how the factors will affect the UCB. This study is to identify maternal, neonatal, obstetric factors that influence the suitability for banking and transplantation of UCB units collection. Study design and methods: This study examined 6534 UCB (3712 at the Catholic Hematopoietic Stem Cell Bank and 2822 at the Daegu Fatima Hospital Public Umbilical Cord Bank) collected at two banks from October 2003 to June 2015. The variables were collected from retrospective records at the time of donation. The associations between TNC, CD34+ and variables including maternal age (MA), gestational age (GA), fetal body weight (FBW), time from collection to processing (T), collecting volume (CV), preTNC, and delivery type were analyzed by logistic regression. Results: In our study cohort (n=6534, male 2988, female 2991, unkown 555, all Koreans), the median values of TNC, numbers of CD34+, MA, GA, FBW, T, preTNC, and CV were 9.24úI108/unit (range, 3.02-35.64), 2.0úI106/unit(range, 0.04-29.2), 31.0 years(range, 15-46), 277 days (range, 202-382), 3330g (range, 1740-4970), 19 hours (range, 1-54), 11.69úI108/unit (range, 3.41-50.32), and 83.5ml (range, 26.0-218.2) respectively. In univariate analysis, variables that were associated with high TNC (defined as a TNC of > 9.24úI108/unit) included GA (defined as GA > 277 days) [OR 1.29 (95% CI 1.16-1.42 p < 0.001)], FBW (defined as FBW > 3330g) [OR 1.52 (95% CI 1.37-1.68 p < 0.001)])], CV (defined as > 83.5mL) [OR 2.61 (95% CI 2.36-2.88 p < 0.001)], preTNC [OR 25.45 (95% CI 22.34-29.00 p < 0.001)], and T (defined as T> 19 hours) [OR 0.87 (95% CI 0.79-0.96 p < 0.005)]. Variables that were associated with high CD34+ (defined as a number of CD34+ > 2.0úI106/unit) included MA (defined as MA > 31.0 years) [OR 0.90 (95% CI 0.82-0.99 P=0.036)], GA [OR 0.74 (95% CI 0.67-0.82 p < 0.001)], FBW [OR 1.41 (95% CI 1.27-1.56 p<0.001)], preTNC [OR 3.38 95% CI 3.06-3.74 p < 0.001]], and CV [OR 1.41 (95% CI 1.28-1.60 p<0.001)] In multivariate analysis of TNC, preTNC [OR 20.71 (95% CI 17.87-24.00) p < 0.001]] was the best predictor of followed by normal delivery [OR 1.77 (95% CI 1.48-2.11 P<0.001)], FBW [OR 1.35 (95% CI 1.17-1.56 p<0.001)], CV [OR 1.31 (95% CI 1.13-1.53 p<0.001)], and female gender [OR 1.21 (95% CI 1.05-1.39 p=0.01)]. In multivariate analysis of CD34, was preTNC [OR 3.39 (95% CI 3.00-3.83 p < 0.001)] was the best predictor of followed by FBW [OR 1.41 (95% CI 1.25-1.58 P<0.001)], GA [OR 0.59 (95% CI 0.52-0.66 p<0.001)], MA [OR 0.84 (95% CI 0.75-0.94 p=0.003)], and female gender [OR 0.89 (95% CI 0.78-0.98 p=0.02)]. Conclusions: We established referential values of cord blood using large scaled CB units in Korea. In multivariate analysis, maternal/donor characteristics were associated with preTNC, FBW, and gender for both high TNC and CD34+. Our results confirm that is similar values to those reported in previous data. These associations could be used to prioritize donations, collections, optimizing resource utilization and financial modeling in Korean cord blood banks. We are focusing on collection education using the standard operation procedure to facilitate of high cells as well as on more recruits of healthy mothers. Disclosures No relevant conflicts of interest to declare.

Download Full-text

Brain metastases in locally advanced NSCLC treated with radical radiotherapy (RT) in a single institution

Journal of Clinical Oncology ◽

10.1200/jco.2007.25.18_suppl.18107 ◽

2007 ◽

Vol 25 (18_suppl) ◽

pp. 18107-18107

Author(s):

O. Hansen ◽

K. H. Hansen ◽

A. Stolberg-Rohr ◽

P. Sorensen

Keyword(s):

Multivariate Analysis ◽

Brain Metastases ◽

Advanced Nsclc ◽

Performance Status ◽

Locally Advanced ◽

Conformal Radiotherapy ◽

Female Gender ◽

Female Ratio ◽

Distant Failure ◽

Locally Advanced Nsclc

18107 Background: Brain metastases (BM) is a major problem in NSCLC. To evaluate the influence on survival in locally advanced NSCLC treated with radical RT, a retrospective analyses was performed of the patients treated at our institution. Methods: From June 1995 to Dec. 2003 200 patients with non-resectable NSCLC stage IIB-IIIAB received radical 3-D conformal radiotherapy with a planned dose =60Gy/30 F. Data on brain metastases were retrospectively obtained from the patient files. All patients were followed to death except in few cases in which data was obtained from other hospitals. End points were occurrence of BM and BM free survival (BM-RFS). A Cox multivariate analysis was performed including possible prognostic factors. Results: Stage at RT: IIB 8 (4%), IIIA 66(33%), IIIB+recurrent disease 126 (63%). Male/female ratio was 126 /74. The median survival was 15.5 months. The 2 yrs. survival was 34%. 42 (21%) cases of BM were observed. The median time to BM was 8.5 ms. with 86% occurring within 2 yrs. In 28 (67%) of the cases BM was the first site of failure, and in 10 (24%) BM remained the only site of failure. More women than men experienced BM 25 (34%) vs. 17 (14%), p= 0.0013. The survival after diagnosis of BM was 2.8 ms. The patients having BM as and these had better prognosis then patients experiencing BM at a later stage 5.3 vs 1.9 ms. (p<0.0001). The prognosis after BM as first failure were no worse than patients having other sites as first distant failure (3.6 ms, p=0.3). In a Cox multivariate analysis only female gender was associated with poorer BM-RFS while use of neoadjuvant chemotherapy, adeno.-histologi, age, stage at RT, and performance status at RT were insignificant factors. Conclusions: A significant number of cases with locally advanced NSCLC experienced BM especially in females. The survival after diagnosis of BM as first failure were no worse than patients experiencing other distant sites as first failure. The results indicates a that PCI should be considered to this group of patients No significant financial relationships to disclose.

Download Full-text