scholarly journals Mycotoxins and Mycotoxin Producing Fungi in Pollen: Review

Toxins ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 64 ◽  
Author(s):  
Aleksandar Kostić ◽  
Danijel Milinčić ◽  
Tanja Petrović ◽  
Vesna Krnjaja ◽  
Sladjana Stanojević ◽  
...  
Keyword(s):  
Metabolic Pathways ◽  
Legal Regulation ◽  
Food Supplement ◽  
Aflatoxin Contamination ◽  
Nutritional Properties ◽  
Toxigenic Fungi ◽  
Eu Legislation ◽  
The World ◽  
Favorable Conditions ◽  
Potential Food

Due to its divergent chemical composition and good nutritional properties, pollen is not only important as a potential food supplement but also as a good substrate for the development of different microorganisms. Among such microorganisms, toxigenic fungi are extremely dangerous as they can synthesize mycotoxins as a part of their metabolic pathways. Furthermore, favorable conditions that enable the synthesis of mycotoxins (adequate temperature, relative humidity, pH, and aw values) are found frequently during pollen collection and/or production process. Internationally, several different mycotoxins have been identified in pollen samples, with a noted predominance of aflatoxins, ochratoxins, fumonisins, zearalenone, deoxynivalenol, and T-2 toxin. Mycotoxins are, generally speaking, extremely harmful for humans and other mammals. Current EU legislation contains guidelines on the permissible content of this group of compounds, but without information pertaining to the content of mycotoxins in pollen. Currently only aflatoxins have been researched and discussed in the literature in regard to proposed limits. Therefore, the aim of this review is to give information about the presence of different mycotoxins in pollen samples collected all around the world, to propose possible aflatoxin contamination pathways, and to emphasize the importance of a regular mycotoxicological analysis of pollen. Furthermore, a suggestion is made regarding the legal regulation of pollen as a food supplement and the proposed tolerable limits for other mycotoxins.

ON THE ADAPTATION OF UKRAINIAN LEGISLATION IN THE FIELD OF ATMOSPHERIC AIR PROTECTION TO THE LAW OF THE EUROPEAN UNION

2018 ◽  
Author(s):  
Viktoriia Bredikhina ◽  
◽  
Yuliya Ignatyuk ◽  
Keyword(s):  
Legal Protection ◽  
Legal Regulation ◽  
International Standards ◽  
The European Union ◽  
Adaptation To Climate Change ◽  
Atmospheric Air ◽  
Best Available Technologies ◽  
Eu Legislation ◽  
The World ◽  
The Eu

Atmospheric air is one of the main vital elements of the environment. The constant growth of the negative anthropogenic impact on it leads to a deterioration in the ecological state of the environment, an increase in morbidity and an increase in the risk of mortality among the population. This article explores the basic principles of legal protection of atmospheric air, on which EU legislation is based. In particular, ‒ is taking into account influences, practical reach, the principle of universality, uncertainty of requirements for specific technologies, the principle of the best available technologies, as well as the principle of "pollutant pays". The authors also analyzed the standards and standards of air quality of the EU, proposed ways to solve the problem of improving national legislation in this area, bringing it in line with international standards. The experience of some European countries proves the need and importance of implementing effective standards of air pollution, since ignoring such normalization can lead to detrimental consequences not only in Ukraine but also around the world. The article states that the regulatory and legal regulation of this sphere in the EU is effective and in a sense exemplary, because with the help of various legal instruments effective air protection is carried out, adaptation to climate change, which makes it possible to properly ensure environmental safety of the population not only in Europe, but also around the world. Ukraine, by adopting relevant regulations at the present stage of the development of legal regulation, takes generally successful steps in the field of approximation of its environmental legislation to EU legislation. However, this process is still gaining momentum and does not exclude problems, contradictions that can inhibit this approximation.

TOURIST BUSINESS DEVELOPMENT IN UKRAINE

2019 ◽  
pp. 39-46
Author(s):  
Stefania Mosiuk ◽  
Igor Mosiuk ◽  
Vladimir Mosiuk
Keyword(s):  
National Economy ◽  
Methodological Approach ◽  
Business Development ◽  
Tourism Industry ◽  
The State ◽  
Complete Analysis ◽  
Resource Potential ◽  
The World ◽  
Potential Resource ◽  
Favorable Conditions

The purpose of the article is to analyze and substantiate the development of tourism business in Ukraine as a priority component of the national economy. The methodology of this study is to use analytical, spatial, geographical, cultural and other methods. This methodological approach provided an opportunity to carry out a complete analysis of the state of the tourism industry of the state and to draw some conclusions.The scientific novelty lies in the coverage of the real and potential resource potential for the development of the recreational and tourism sphere in Ukraine, detailing the measures for the country ‘s entry into the world tourist market. Conclusions. Analyzing the state and prospects of tourism business development in Ukraine, it should be noted that this industry is one of the priority areas for improving the economy of the country. Historical, cultural – ethnographic, gastronomic, sanatorium and resort potentials of the country will lead the country into world leaders of the tourism industry when creating favorable conditions for investment and proper marketing.

scholarly journals Aflatoxin contamination in food crops: causes, detection, and management: a review

2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Abhishek Kumar ◽  
Hardik Pathak ◽  
Seema Bhadauria ◽  
Jebi Sudan
Keyword(s):  
High Temperature ◽  
Aspergillus Parasiticus ◽  
Fungal Species ◽  
Aflatoxin Contamination ◽  
Food Crops ◽  
Farming Practices ◽  
Resistant Varieties ◽  
Food Commodities ◽  
Post Harvesting ◽  
Favorable Conditions

AbstractMycotoxins are secondary metabolites produced by several fungal species and molds. Under favorable conditions like high temperature and moisture, they contaminate a large number of food commodities and regional crops during pre and post-harvesting. Aflatoxin is the main mycotoxin that harm animal and human health due to its carcinogenic nature. Aflatoxins are mainly released by Aspergillus flavus and Aspergillus parasiticus. AFB1 constitutes the most harmful type of aflatoxins and is a potent hepato-carcinogenic, mutagenic, teratogenic and it suppresses the immune system. To maintain food safety and to prevent aflatoxin contamination in food crops, combined approaches of using resistant varieties along with recommended farming practices should be followed. This review concentrates on various aspects of mycotoxin contamination in crops and recent methods to prevent or minimize the contamination.

Identification of novel cardiovascular disease associated metabolites using untargeted metabolomics

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Shams Tabrez ◽  
Mohammed Razeeth Shait Mohammed ◽  
Nasimudeen R. Jabir ◽  
Mohammad Imran Khan
Keyword(s):  
Cardiovascular Disease ◽  
Metabolic Pathways ◽  
Enrichment Analysis ◽  
Pathway Enrichment Analysis ◽  
Healthy Individuals ◽  
Great Opportunity ◽  
Pathway Enrichment ◽  
Pathophysiological Role ◽  
The World ◽  
Metabolomic Approach

Abstract Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality around the world. Early diagnosis of CVD could provide the opportunity for sensible management and better clinical outcome along with the prevention of further progression of the disease. In the current study, we used an untargeted metabolomic approach to identify possible metabolite(s) that associate well with the CVD and could serve either as therapeutic target or disease-associated metabolite. We identified 26 rationally adjusted unique metabolites that were differentially present in the serum of CVD patients compared with healthy individuals, among them 15 were found to be statistically significant. Out of these metabolites, we identified some novel metabolites like UDP-l-rhamnose and N1-acetylspermidine that have not been reported to be linked with CVD directly. Further, we also found that some metabolites like ethanolamide, solanidine, dimethylarginine, N-acetyl-l-tyrosine, can act as a discriminator of CVD. Metabolites integrating pathway enrichment analysis showed enrichment of various important metabolic pathways like histidine metabolism, methyl histidine metabolism, carnitine synthesis, along with arginine and proline metabolism in CVD patients. Our study provides a great opportunity to understand the pathophysiological role and impact of the identified unique metabolites and can be extrapolated as specific CVD specific metabolites.

Extracts of Agave americana inhibit aflatoxin production in Aspergillus parasiticus

2011 ◽  
Vol 4 (1) ◽  
pp. 37-42 ◽  
Author(s):  
A. Rosas-Taraco ◽  
E. Sanchez ◽  
S. García ◽  
N. Heredia ◽  
D. Bhatnagar
Keyword(s):  
Aspergillus Parasiticus ◽  
Public Awareness ◽  
Aflatoxin Production ◽  
Aflatoxin Contamination ◽  
Aqueous Extracts ◽  
Total Aflatoxin ◽  
Toxigenic Fungi ◽  
Agave Americana ◽  
Acid Accumulation ◽  
Norsolorinic Acid

Toxigenic fungi invade crops prior to harvest as well as during storage and produce harmful, even carcinogenic toxins such as aflatoxins. Since consumers demand safe commodities, and due to enhanced public awareness of the dangers of many synthetic fungicides, the importance of investigating alternative, natural products to control these toxigenic fungi is clear. This study investigated the effect of aqueous extracts of Agave americana on growth, conidia and aflatoxin production. Aspergillus parasiticus strains SRRC 148, SRRC 143 (Su-1), and A. parasiticus SRRC 162, a mutant (nor-) that accumulates norsolorinic acid (NOR, an orange-coloured intermediate of the aflatoxin pathway), were first inoculated into Adye and Mateles liquid medium, then plant extracts were added, and incubated at 28 °C for 7 days. Aflatoxin and norsolorinic acid were assayed by HPLC and spectrophotometry, respectively. While the extract of A. americana stimulated growth of the studied fungi, conidiogenesis, norsolorinic acid accumulation (in the nor- mutant), and aflatoxin production were significantly affected. The reduction was produced by the extracts at concentrations higher than 5-10 mg/ml, where all types of total aflatoxin analysed (aflatoxins B1, B2, G1 and G2) were reduced from 64% to >99% in the whole culture, and a reduction of 75% of norsolorinic acid. The results of the present work indicate that extracts of A. americana may be promising safe alternatives to harmful fungicides for controlling aflatoxin contamination.

National Library of Uzbekistan: from the history of formation and the current stage of development

Infolib ◽  
2020 ◽  
Vol 24 (4) ◽  
pp. 2-8
Author(s):  
Umida Teshabaeva ◽  
Keyword(s):  
New Technologies ◽  
Public Library ◽  
National Library ◽  
Stage Of Development ◽  
The World ◽  
History Of ◽  
The Republic ◽  
Favorable Conditions ◽  
History Of Formation ◽  
Current Stage

The article is devoted to the history of the Tashkent Public Library, at the origins of which were prominent scientists of that time, to the present day of the National Library of Uzbekistan. The library fund has more than 7.5 million items in 75 languages of the world. The National Library is the main methodological center of information and library institutions of the Republic. Creation of favorable conditions for readers is one of the priority tasks of the library, which is improved every year by the introduction of new technologies for obtaining information in an operational way. Thanks to membership in the International Consortium «eIFL», users have access to 38 foreign educational databases, 12 of which are licensed. Also, library readers get access to national and world educational collections in different languages of the world.

REFORM OF LEGAL REGULATION OF REMOTE WORK AS A STIMULATION FOR ENTREPRENEURSHIP DEVELOPMENT IN RUSSIA

2020 ◽  
pp. 136-143
Author(s):  
Maria A. Andrianova ◽  
Keyword(s):  
Labor Law ◽  
Legal Regulation ◽  
Remote Work ◽  
High Quality ◽  
Quality Work ◽  
Entrepreneurship Development ◽  
Short Period ◽  
The World ◽  
Work Done ◽  
Usual Order

The pandemic has created many difficulties for entrepreneurs around the world, including in Russia. As you know, difficulties, disrupting the usual order, can give impetus for radical changes that would not have a chance to be realized in times of peace and prosperity. It seems that remote mode is not suitable for all forms of employment, but if initially the employer assumes such an opportunity, the main problem is not the lack of the ability to control the employee, but ensuring effective communication with him and the ability to timely obtain the results of high-quality work done. It is noted that this goal can be achieved with the help of greater detail in local regulations of the order and conditions of interaction between the employee and the employer. One of the most promising consequences of the pandemic has been the reform of the legal regulation of remote work. In a very short period of time, remote work in Russia from an unviable rudiment has become one of the most progressive institutions, which has every chance of making all labor law more flexible and effective. Such labor law will undoubtedly become one of the incentives for the development of entrepreneurship in Russia.

scholarly journals The problem of waste in the Russian Federation

2018 ◽  
Vol 193 ◽  
pp. 02030 ◽  
Author(s):  
Kseniya Kovalenko ◽  
Nataliya Kovalenko
Keyword(s):  
Russian Federation ◽  
Environmental Safety ◽  
Legal Regulation ◽  
Global Scale ◽  
Waste Utilization ◽  
Industrial Wastes ◽  
Household Waste ◽  
Solid Domestic Waste ◽  
The World ◽  
The Russian Federation

This article discusses the problems of environmental safety in the sphere of disposing of domestic and industrial wastes in the environment as one of the most important aspects of sustainable development of society. At present, this problem is one of the top priorities and is being solved at the world level. With the emergence of the consumer nature of society, the issue of waste disposal becomes more acute, requiring immediate solutions on a global scale. At present, the quantity and variety of solid household waste (MSW) in the countries is rapidly increasing. This is typical not only for industry, agriculture, megacities, but also for individual residents. At the beginning of 2014, the Russian Federation accumulated more than 35 billion tons of waste. The problem of garbage is not just a difficulty, but a global environmental challenge. One of the main reasons is that there are no mechanisms for regulating the market for collection and processing of solid domestic waste in Russia. We can also say that there is a shortage of specialists in this field, competent managers capable of establishing the entire chain of waste utilization. In the Russian Federation, this problem is as acute as it is throughout the world. Unauthorized landfills are one of the components of this problem. The state should pay more attention to legal regulation of this issue, engage in environmental and legal culture of citizens in order to prevent the emergence of unauthorized landfills, their prompt liquidation, and protect the constitutional rights of citizens to an environmentally safe environment.

scholarly journals Cyber Bulling in Modern Conditions: Possibilities of Legal Regulation

2021 ◽  
pp. 097-103
Author(s):  
O. P. Kopylova ◽  
◽  
S. V. Medvedeva ◽  
Yu. V. Kalashnikova ◽  
◽  
...  
Keyword(s):  
Aggressive Behavior ◽  
Legal Regulation ◽  
Cyber Bullying ◽  
The Internet ◽  
Emotional States ◽  
The World

Possibilities of legal regulation of cyber bullying are considered in modern conditions. Aggressive behavior in the Internet space is gaining momentum in its distribution among adolescents not only in Russia but throughout the world. Cyber bullying is one of the newest, most dangerous, and also depressing emotional states of a teenager in terms of the consequences of the risk they face. The concept of “cyber bullying” is considered; its forms are specified; proposals aimed at neutralizing the bullying that occurs among adolescents in the Internet space are formulated.

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