The influence of probiotic drug Biolax-U on morphological and biochemical parameters of blood in cows

2020 ◽  
pp. 70-76
Author(s):  
A. Farkhutdinova
Keyword(s):  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Experimental Studies ◽  
Positive Influence ◽  
Biologically Active ◽  
Feed Consumption ◽  
Control Group ◽  
Animal Blood ◽  
Black And White ◽  
White Breed

The expediency of using the probiotic drug Biolax-U in the rations of lactating and dry cows of Black-and-White breed has been studied and scientifically proved. The influence of this drug on the morphological and biochemical parameters of animal blood has been determined. The composition of the probiotic drug Biolax-U consists of eight strains of a balanced complex of living lactic acid bacteria, yeast and actinomycetes, as well as biologically active substances. For experimental studies conducted on 2 groups of cows have been selected by the method of pairs-analogs, the influence of feeding of feed have been prepared with the use of the microbiological drug with probiotic action Biolax-U on feed consumption, morphological and biochemical changes in blood has been studied. Analysis of the rations of cows indicates that the content of calcium, phosphorus, magnesium, sulfur and trace elements such as manganese, copper, zinc and cobalt in the feed has been reduced. It has been found by studies that the use of probiotic drug Biolax-U had the positive influence on the feed intake, digestibility and better assimilation of feed nutrients and contributed to the improvement of blood morphological and biochemical parameters. For example, in animals of the experimental group hemoglobin has increased by 3,6 % (Р < 0,05), red blood cells by 10,1 (P ≤ 0,05), the content of leukocytes by 4,43, carotene by 9,6, glucose by 3,4; reserve alkalinity by 15,6, calcium by 19,4 (P ≤ 0,01), and phosphorus by 18,4 % compared with the control group of animals. During the lactation significantly improved hematological parameters including alkalinity reserve by 5,11 %, calcium level by 11,1, phosphorus by 8,6, hemoglobin by 14,2 %, the content of erythrocytes by 12,3, leukocyte by 3,86, and carotene 11,1 % against the parameters of animals of control group. The improvement of morphological and biochemical parameters of blood of cows indicates about stimulating effect on hematopoiesis and the general clinical condition of animals that contributes to the improvement of metabolic processes when using feed prepared with the use of microbiological drug with probiotic action Biolax-U.

Extruded lupine as a part of energy-protein concentrate in the ration of lactating cows

2020 ◽  
pp. 65-73
Author(s):  
Z. Fedorova
Keyword(s):  
Farm Animals ◽  
Feed Consumption ◽  
Control Group ◽  
Protein Concentrate ◽  
Cattle Farm ◽  
Black And White ◽  
Lactating Cows ◽  
White Breed ◽  
Kaliningrad Region ◽  
Experimental Group

In order to fi ll the existing protein defi ciency in the rations of farm animals in particular dairy cows it is necessary to input feed lupins as widely as possible in crop rotations. Lupin is a very versatile forage crop it can be used in feed as herbage, in the form of haylage, silage, in compound feed as a protein additive, as well as a green manure crop to increase soil fertility. Questions of protein nutrition should be to be quickly resolved, both in the production of protein and in its standardized rational use. Unbalanced protein rations increase feed consumption per unit of production, thereby increasing its prime cost. In the world soya is generally recognized as a protein feed, but in the Kaliningrad region as in most of regions in our country, it does not maturate being a heat-loving crop. Under these environments the inclusion of extruded lupine grain in the composition of energy-protein concentrates for the production of compound feed has become an alternative to replacing expensive soya. The researches have been carried out it the cattle farm of LLC “Temp” in the Guryevsky area in the Kaliningrad region (March-May 2019) on feeding lactating cows energy-protein concentrate from extruded grain of narrow-leaved lupine, fl ax, triticale, subjected to heat treatment on a press extruder. For this purpose two groups of lactating cows of Black-and-White breed (control and experimental) have been formed using the method of pairs of analogs per 11 heads in each. Cows of the control group have received the main ration of the farm, and cows of the experimental group in addition to the main ration have received compound feed with extruded energy-protein concentrate based on lupine. As a result of research, the positive infl uence of energy-protein concentrate based on lupine in compound feed on the dairy productivity of cows has been established. Recipes of concentrate and compound feed with concentrate for lactating cows, the volume of inclusion of components in the concentrate and in the compound feed have been calculated. During the experiment, the milk yield in the experimental group of cows has increased by 62,4 kg or 8,0 %, than in the control group. From the cows of the experimental group the conditional profi t has been received in the amount of 1684,8 rubles per head.

Milk productivity and quality of milk of cows of Black-and-White breed when feeding a balanced feed complex Felucen K 1–2

2020 ◽  
pp. 17-28
Author(s):  
V. Minibaev ◽  
N. Gubaidullin
Keyword(s):  
Crude Protein ◽  
Dry Matter ◽  
Metabolic Energy ◽  
Crude Fiber ◽  
Feed Consumption ◽  
Control Group ◽  
Milk Productivity ◽  
Black And White ◽  
White Breed ◽  
Digestible Protein

The analysis of the literature data shows that there is not enough information on the enrichment of the ration of cows of Black-and-White breed with a balanced feed complex Felucen K 1–2 that has caused the relevance of our researches. The purpose of the research was to increase the productive qualities of cows Black-and-White breed when using different doses of the balanced feed complex Felucen K 1–2 in their ration. The studies have been carried out in the Southern Urals, the optimal dose of use of feed complex Felucen K 1–2 that enhance milk productivity of cows of Black-and-White breed. According to the scheme of the experiment cows of the 2nd, 3rd and 4th experimental groups have been additionally fed to main ration 300 g, 350 and 400 g of the balanced feed complex Felucen K 1–2, consisting of vegetable protein and fat, easily fermentable carbohydrates, high-purity sodium chloride, macronutrients, trace elements, and vitamins. Animals of the 1st group have been served as control and complex Felucen have not been received. Studies have shown that cows of the 1st control group used less dry matter, EFU, metabolic energy, digestible protein, crude protein, crude fiber, and crude fat than their experimental herdmates. Thus, the superiority of cows of the experimental groups over the herdmates of the 1st control group in terms of EFU was 93,1–231,2 kg; metabolic energy – 933,7–2314,7 MJ; dry matter – 9,0–125,8; digestible protein – 8,9–29,7; crude protein – 4,6–18,3; crude fiber-13,1–48,4; crude fat – 11,6–21,0 kg. Animals of all experimental groups in comparison with the control group exceeded in terms of milk yield for 305 days of lactation by 435,2 kg or 6,60 % (P < 0,001); 814,4 kg or 12,34 % (P < 0,001); 684,1 kg or 10,37 % (P < 0,001); for 100 days of lactation – by 98,7 kg or 4,28 % (P < 0,001); 191,0 kg or 8,29 % (P < 0,001) and 167,8 kg or 7,28 % (p<0,001), respectively. The use of Felucen K 1–2 feed complex in the rations of lactating Black-and-White cows has shown its effectiveness, which has affected the feed consumption and effectiveness of their use, hematological indicators, the level of milk productivity and milk quality. From an economic point of view the dose of 350 g of balanced feed complex Felucen To 1–2 per animal per day is more reasonable.

The effectiveness of feeding complex mineral and vitamin feed additive «Nadezhda» to lactating cows

2021 ◽  
pp. 30-37
Author(s):  
A. R. Farkhutdinova ◽  
M. T. Sabitov ◽  
M. G. Malikova
Keyword(s):  
The Body ◽  
Metabolic Energy ◽  
Feed Consumption ◽  
Feed Additive ◽  
Control Group ◽  
Black And White ◽  
Lactating Cows ◽  
White Breed ◽  
Quality Of Milk ◽  
Experimental Group

The feasibility of using the complex mineral and vitamin feed additive “Nadezhda” in the rations of lactating first-calf heifers of Black-and-White breed has been examined in the article. It has been established that feed contain a low content of elements such as calcium, phosphorus, magnesium, sulfur, manganese, copper, zinc and cobalt. The ratio of nutrients and minerals, the degree of their availability for assimilation by the body does not provide their need. The use of the complex mineral and vitamin feed additive contributed to an increase in the milk productivity of first-calf heifers and the quality of milk, feed consumption per unit of production. All tested recipes of the complex mineral and vitamin feed additive, which have different versions of macro-, microelements and vitamins in their composition had a positive effect on the metabolic processes in the body of animals. For the production of 1 kg of milk in the experimental groups of cows less metabolic energy was spent by 5,09 (P < 0,05) and 8,06 % (P < 0,05), respectively, raw protein by 5,19 and 8,19 % (P < 0,05), digestible protein by 5,12 (P < 0,05) and 8,15 % (P < 0,05) compared with the animals of the control group. At the same time from the cows of the 1st experimental group have been received more milk by 151,6 kg in the amount of 2489 rubles, from the 2nd experimental group by 250,6 kg of milk in the amount of 4248,0 rubles. The prime cost of production of 1 kg of milk in cows of the 1st experimental group in comparison with the animals of the control group decreased by 0,72 rubles, and the 2nd experimental group by 1,21 rubles. The level of profitability of milk production in cows have been fed with additive recipe No. 1, in comparison with the animals of the control group increased by 3,71 abs.%, recipe No. 2 by 9,91 abs.%.

Influence of a complex feed additive on the morphological and biochemical parameters of the blood of first-calf heifers during the period of increasing the milk yield

2021 ◽  
pp. 31-39
Author(s):  
M. T. Sabitov ◽  
A. R. Farkhutdinova ◽  
M. G. Malikova ◽  
Yu. A. Karmatskikh
Keyword(s):  
Milk Yield ◽  
Biochemical Parameters ◽  
Blood Parameters ◽  
The Body ◽  
Feed Additive ◽  
Control Group ◽  
Black And White ◽  
White Breed ◽  
The Republic ◽  
Experimental Group

It is known that mineral additives play an important role in increasing the productivity and efficiency of the animal husbanry industry as a whole. The state of the body can be assessed by the content of mineral substances in a blood test. The purpose of the work was to study changes in morphological and biochemical blood parameters in first-calf heifers during the period of increasing the milk yield when they are fed a complex mineral and vitamin feed additive (CMVFA). The study of the influence of feeding the complex mineral and vitamin feed additive in the ration to first-calf heifers during the the period of increasing the milk yield on morphological and biochemical blood parameters has been carried out. The experiments were carried out in 2019–2020 in the OOO Breeding Farm “Valiev” in the Dyurtyulinsky district in the Republic of Bashkortostan on 3 groups of first-calf heifers of Black-and-White breed per 15 heads in each selected by the method of pairs of analogues. The animals of the control group received the main ration (MR) adopted on the farm, the 1st experimental group MR+120 g/head CMVFA according to the recipe No. 1, the 2nd experimental group MR+120 g/head CMVFA according to the recipe No. 2. In the ration of animals of the control group there was a deficiency of basic macro- and microelements. The use of CMVFA as part of the ration of first-calf heifers during the period of increasing the milk yield had a positive effect on the morphological and biochemical parameters of blood. Studies have shown that the use of CMVFA in the rations of first-calf heifers provided the need for minerals and vitamins, accelerating metabolic processes in the body during the most stressful period of lactation, the period of increasing the milk yield. According to the results of biochemical blood parameters, it is possible to esimate the improvement of protein, carbohydrate and mineral and vitamin nutrition in the first-cakf heifers of the experimental groups during the period of increasing the milk yield, which showed their genetic potential more fully and used nutrients more effectively for milk synthesis.

The use of feed additives «MegaStimImmuno» and Herbafarm L in feeding of young pigs

2020 ◽  
pp. 37-50
Author(s):  
I. Gorlov ◽  
G. Komlatsky ◽  
E. Cheruvimskikh
Keyword(s):  
Raw Materials ◽  
Mineral Metabolism ◽  
Hematological Parameters ◽  
Average Daily Gain ◽  
Positive Influence ◽  
Feed Additives ◽  
Biologically Active ◽  
Control Group ◽  
Young Pigs ◽  
Daily Gain

It is known that without addressing the issues of balanced feeding other measures for the development of pig breeding do not give the necessary effect. One of the promising directions of improving the productivity of pigs and to increase the volume of production of raw materials in industrial technology may be the use of biologically active additives that improve the palatability of feed, promote the metabolism, and increase body resistance. Complex researches on scientific substantiation and experimental confi rmation of high effectiveness of innovative feed additives “MegaStimImmuno” and Herbafarm L in feeding of young pigs when pork production have been carried out. The use of feed additives “MegaStimImmuno” and Herbafarm L in the diets of young pigs contributes to the normalization and activation of protein, carbohydrate and mineral metabolism, strengthen immunity and ultimately increase the productivity of animals and improve the biological value and technological properties of meat of young pigs. The analysis of the data has been obtained to estimate the growth intensity in terms of the average daily gain of young pigs confirmed the established pattern. For the entire period of rearing and fattening animals (5–167 days) in the 1st experimental group daily gain 678,80 g has been obtained an average, which was by 49,7 g or 7,90 % (P < 0,001), in the 2nd experimental 664,45 g, which was by 35,29 g or 5,61 % (P < 0,001) higher than in the control group. The positive influence of biologically active feed additives on consumption, digestibility, metabolism of nutrients in young pigs, hematological parameters, productivity, quality of meat and fat has been established.

Productivity and technological qualities of pork when using biological drugs

2020 ◽  
pp. 12-28
Author(s):  
O. Mikheeva ◽  
V. Fedyuk ◽  
M. Slozhenkina
Keyword(s):  
Endocrine Cells ◽  
Intestinal Microflora ◽  
Biologically Active ◽  
Large White ◽  
Biological Drugs ◽  
Animal Blood ◽  
Intestinal Microbiology ◽  
White Breed ◽  
Meat Productivity

In world practice biologically active drugs are widely used at different technological stages of rearing pigs, poultry and cattle. Special attention should be paid to bio-grugs obtained not as a result of chemical synthesis, but isolated from organs and tissues of healthy animals. Restoration of normal intestinal microflora of the animal is the basis of the concept of probiotics. Currently, probiotics are considered as endogenous intestinal microflora most often belonging to the group of lactobacilli, streptococci or bifidobacteria or as specific growth factors for them. Probiotics are selected according to certain criteria based on scientific knowledge of the physiology of intestinal microbiology, as well as animal nutrition. The purpose of the work was to study the effect of biological products on resistance, reproductive, fattening and meat productivity of pigs, on the quality of whole-muscle and fine-structured pork products; to develop a method of application of duodenum extract in combination with probiotics to increase the productivity of pigs. Studies on the effect of extracts derived from endocrine cells of the intestine, in combination with probiotics on the productivity of pigs of Large White breed and the quality of pork, as well as studied the effect of duodenins and probiotics in different concentrations on the protective properties of animal blood have been carried out. New methods of application of extracts of endocrine cells of intestines and probiotics for increase of meat productivity of animals and quality of pork have been offered. The use of bio-drugs increased the livability of young animals in all experimental groups from 1st to 4st by 3,51; 6,05; 4,95 and 5,90 %, respectively. There was an advantage in the amount of revenue from the sale of products of all experimental groups over the control one.

Hematological condition of breeding bulls after a long winter period of operation in the conditions of the Udmurt Republic

2022 ◽  
pp. 67-73
Author(s):  
A. Abilov ◽  
A. Azhmyakov ◽  
I. Novgorodova ◽  
N. Bogolyubova
Keyword(s):  
Red Blood Cells ◽  
Reference Values ◽  
Blood Cells ◽  
Hematological Parameters ◽  
White Blood Cells ◽  
Winter Period ◽  
Black And White ◽  
Significant Difference ◽  
White Breed ◽  
Udmurt Republic

Purpose: to study hematological parameters of blood in bulls-producers of dairy breeds on the day of semen collection in the Udmurt Republic after a long winter period of operation, depending on the breeds, age and place of selection.Materials and methods. The work was performed at the Federal Research Center for Animal Husbandry named after Academy Member L. K. Ernst on the basis of AO "Udmurtplem" of the Udmurt Republic in the period from 2020 to 2021 on dairy bulls (n=20) aged 15-69 months, including a purebred Holstein breed of domestic selection (n=6), a Holstein black-and-white breed of European selection (the Netherlands, n=6), a black-and-white breed with blood transfusion on Holsteins on at the level of 94-98% (n=8). The content of white blood cells, red blood cells, hemoglobin and hematocrit, depending on age and breed, was studied on the ABC VET hematological analyzer on the day of taking the seed.Results. It was found that on average, in 20 bulls aged 15-69 months, the level of white blood cells was at the level of reference values of 8.8±0.25 x 109/l, red blood cells 10.3 x 1012/l, which is 50% more than the reference values. The concentration of hemoglobin is 128.0±2.92 g/l, hematocrit is on average 54.3%, with a norm of 24-46%. Breeding bulls at a reliable level, differing in age, showed that some animals had high indicators for red blood cells of 10.3±0.26 x 102, for hematocrit of 54.3% against 24-46% of reference values. Also, according to hematological indicators, there was a tendency to increase the concentration of hemoglobin and hematocrit in European-bred bulls.Conclusion. The study of the variability in hematological parameters depending on the selection showed that there is no significant difference in leukocytes and all indicators are at the level of reference values, and in erythrocytes more than 50% than the highest indicators. The highest hemoglobin values were at the level of 141-156 g/l instead of 128 g/l according to the highest reference values. Hematocrit also showed high max values in all groups in comparison with the reference values of 59-66% versus 46% in the norm. It is necessary when analyzing hematological blood parameters in addition to the average statistical indicators (M+m) also, monitor the variability (min-max) in order to obtain more objective information.

scholarly journals RESVERATROL INCLUSION COMPLEX WITH β-CYCLODEXTRIN (RCD): CHARACTERIZATION AND EVALUATION OF TOXICITY IN WISTAR RATS

2016 ◽  
Vol 9 (1) ◽  
pp. 27 ◽  
Author(s):  
V. S. K. Nishihira ◽  
N. J. Mezzomo ◽  
M. D. Baldissera ◽  
R. A. Vaucher ◽  
C. G. Pinto ◽  
...  
Keyword(s):  
Inclusion Complex ◽  
Oral Administration ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Metabolic Diseases ◽  
Hematological Parameters ◽  
Density Lipoprotein ◽  
Blood Parameters ◽  
Control Group ◽  
Scanning Calorimetry

<p class="RSCB01ARTAbstract"><strong>Objective</strong>:<strong> </strong>The aim of this study was to characterise the resveratrol inclusion complex with β-cyclodextrin (RCD) and evaluate their toxicity in wistar rats.</p><p class="RSCB01ARTAbstract"><strong>Methods: </strong>The RCD were prepared in ultra-turrax. For characterization of the RCD were used: Fourier transform infra-red Spectroscopy, Nuclear Magnetic Resonance (NMR), Differential Scanning Calorimetry (DSC) and X-ray powder diffraction. The RCD and others 4 treatments were performed by the chronic oral administration in 35 rats during 60 ds. After the treatments they were euthanized and the serum blood were collected to analyzed some hemogram and biochemical parameters including aspartyl aminotransferase (AST); alanine aminotransferase (AST); phosphatase alkaline (ALP); total bilirubin (TB); direct bilirubin (DB); total protein (TP); total cholesterol (TC), triacylglycerol (TAG), very low-density lipoprotein (VLDL), high-density lipoprotein (HDL), calcium, iron and phosphate using fully automated biochemistry analyzer.</p><p class="RSCB01ARTAbstract"><strong>Results: </strong>The characterization results indicated a successful formation of the RCD. All hematological parameters analysed were within the normal values in all the groups. Furthermore, the hemogram and biochemical parameters were significantly (P&gt;0.05) similar to the control group.</p><p class="RSCB01ARTAbstract"><strong>Conclusion: </strong>The daily oral administration during 60 d of RCD are not harmful on blood parameters of Wistar rats. Thus, RCD can be used safely for treatment of some metabolic diseases.</p>

scholarly journals Influence of Pesticide on Biochemical and Hematological Parameters in Beninese Vegetable Farmers

2018 ◽  
Vol 9 (1) ◽  
pp. 65
Author(s):  
Lucie AYI-FANOU
Keyword(s):  
Blood Cell ◽  
Biochemical Parameters ◽  
Mean Corpuscular Volume ◽  
Hematological Parameters ◽  
Control Group ◽  
Study Group ◽  
Blood Samples ◽  
Vegetable Farmers ◽  
Insignificant Difference ◽  
Hematological And Biochemical Parameters

In several countries, a lot of researches have shown the toxicity of pesticides on farmers. Meanwhile, few of them have dealt with vegetable farmers in Benin. Therefore, this study has been carried out to assess the effects of pesticides on vegetable farmers’ health. This study is conducted on 30 vegetable farmers who used pesticides and 20 subjects as control group. Pesticides used by vegetable farmers and their risky behavior were investigated. Their blood samples were collected and some tests were performed for hematological and biochemical parameters. For the statistical analysis of the results, Student’s test was used. Our investigations revealed that vegetable farmers of Benin were exposed to different active ingredients of pesticides such as (Abamectin, Acetamiprid, Chlorpyriphos ethyl, Cyfluthrin, Cypermethrin, Emamectin benzoat, Flubendiamid, Lambdacyhalothrin, Mancozeb, Profenofos, Spinosad and Spirotétramate). The hematological parameters showed significant decrease in White blood cell (WBC), Red blood cell (RBC), Hemoglobin (HGB), Hematocrit (HTC), Mean Corpuscular Volume (MCV), Platelet (PLT) count among study group. The enzymatic activities of Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT) have significantly raised between vegetable farmers and the control group, while the serum concentration in urea and creatinine showed insignificant difference in the study group. These results suggest that pesticides have adverse effects on vegetable farmers of South of Benin.

scholarly journals A 90-Day Oral Toxicity of Hydroethanolic Root Extract of Carissa spinarum in Wistar Rats

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Komlan M. Dossou-Yovo ◽  
Aboudoulatif Diallo ◽  
Povi Lawson-Evi ◽  
Yendubé T. Kantati ◽  
Tchin Darré ◽  
...  
Keyword(s):  
Body Weight ◽  
Biochemical Parameters ◽  
Wistar Rats ◽  
Hematological Parameters ◽  
Relative Weight ◽  
Control Group ◽  
Root Extract ◽  
Weight Changes ◽  
Oral Toxicity ◽  
Significant Difference

Background. Herbal medication is a worldwide and ancient practice, mostly in developing countries, where a large part of the population is involved in this practice. Hence, studies must be conducted to evaluate their safety and efficiency to avoid or prevent toxicological risks due to their usage. In Togo, Carissa spinarum is a medicinal plant belonging to Apocynaceae family, used as an aphrodisiac or to heal some ailments including malaria, sickle cell anemia, hypertension, pain, and asthma. Notwithstanding its several ethnomedicinal benefits, just a few toxicological data associated with its chronic use are available. Objective. Therefore, this study aims to assess the toxicity of an ethanolic root extract of Carissa spinarum in Wistar rats. Methods. The 90-day oral toxicity process following OECD TG 408 guidelines is used. Male Wistar rats received Carissa spinarum root hydroethanolic extract at 500 and 1000 mg/kg for 90 days by oral gavage. Body weight changes, hematological and blood biochemical parameters, organ weight changes, malondialdehyde as a lipoperoxidation marker expressed according to tissue proteins, and histopathology of vital organs were assessed. Results. No signs of toxicity or mortality were observed during the 90 days experiment. Hematological parameters have not shown any treatment-related abnormalities. According to biochemical parameters, an increase in the chloride ion level was observed at 1000 mg/kg p < 0.01 . There was no significant difference between the treated groups and the control group concerning the malondialdehyde concentration, body weight, and organ relative weight. No changes in necropsy and histopathology of vital organs associated with extract treatment were observed. Conclusion. The results indicated that an ethanolic root extract of Carissa spinarum does not cause adverse effects, which can lead to Wistar rats’ death after 90-day oral administration at 500 and 1000 mg.

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