THE EFFECT OF FEED ADDITIVE ACID LAC DRY AND ITS COMBINATIONS WITH PROBIOTIC PROLAM ON THE PROCESS OF INTESTINAL MICROBIOCENOSIS FORMATION IN CALVES WITH HYPOTROPHY

Author(s):  
A. G. Shakhov ◽  
◽  
L. Yu. Sashnina ◽  
I. T. Shaposhnikov ◽  
O. A. Manzhurina ◽  
...  

The article represents the data on studying the effect of feed additive Acid Lac Dry, probiotic Prolam and their complex application to calves with hypotrophy during colostral period on intestinal microbiocenosis formation. Researches were carried out on 32 newborn calves with hypotrophy of Holstein-Frisian rocks, which formed 4 groups (n=8). The drugs were not used for the animals of the 1st (control) group. Calves of experimental groups were prescribed orally in the 1st week of life: Asid Lak Dry 15,0 gramms as an aqueous suspension (group 2), probiotic Prolam with colostrum (milk) 5...7 cm3 (3rd group), Asid Lak Dry in combination with Prolam at indicated doses (4th group). The 1st day the preparations were prescribed after the colostrum had been drunk, and Asid Lak Dry – in the following days. During the period of application of the feed additive and probiotics, antimicrobials drugs were not prescribed. A positive effect of both preparations and especially their combination on normobiosis formation is demonstrated. This significantly prophylaxed gastrointestinal diseases of animals and decreased the duration of their treatment under their emergence.

Author(s):  
T. V. Zubova ◽  

The article presents the results of studying the effect of the drug Azoxivet on the organism of young black-and-white cattle in the conditions of the commercial economy of the Kemerovo region in 2020. When using the drug, a positive effect on the formation of immune defense and resistance of the body of calves is noted. The formation of strong immunity and resistance of the organisms of the calves of the experimental group influenced the growth rate of the experimental livestock. During the study period, gastrointestinal diseases of calves with diarrhea symptoms were observed in the control group 2 times more often than in the experimental group.


2020 ◽  
Vol 50 (2) ◽  
pp. 185-193
Author(s):  
Roman Voroshilin ◽  
Marina Kurbanova ◽  
Sergey Rassolov ◽  
Elena Ul'rih

Introduction. Rabbit meat is an excellent source of dietetic food. High-quality and safe meat production is a priority of the scientific and technological development of the Russian Federation. The research objective was to determine the optimal dose of Echinacea purpurea L. extract in the rabbit diet and study its effect on the physicochemical and morphological quality parameters of rabbit meat. Study objects and methods. At 70 days of age, the experimental animals started to receive various doses of a phytobiotic feed additive based on the Echinacea purpurea extract. The experiment lasted 30 days. Results and discussion. The daily dose of 1.0 g and 1.5 g per animal proved to stimulate the redox processes in the rabbit metabolism. The body weight of the test animals significantly increased compared with the control group. The test slaughter revealed a high level of meat productivity. The animals in experimental groups II and III showed the best slaughter indicators. Each animal received 1.5 g of the extract per day. The morphological composition of chilled carcass indicated that the additive had a positive effect on the mass indicators. According to the physical and chemical analysis, the contents of water, protein, and ash in the experimental group was the same as in the control group. The ratio of unsaturated and saturated fatty acids in the control group was 1.34:1, while in the experimental group III is was 1.39:1. This optimal proportion proved a high biological value of rabbit meat, which makes it a dietary product. The phytobiotic additive proved commercial as the test animals demonstrated an intensive weight gain compared with the control group. Experimental groups II and III showed the best slaughter indicators. Conclusion. 1.5 g of the extract of Echinacea purpurea had a positive effect on the composition and physicochemical parameters of rabbit meat, as well as meat production.


2016 ◽  
Vol 1 (3) ◽  
pp. 40-45
Author(s):  
Долженкова ◽  
Galina Dolzhenkova ◽  
Галиева ◽  
Zulfiya Galieva

The purpose of the research is improving the efficiency of energy utilization of diets for Black-motley breed bull-calves through the use of probiotic drug Biogaran.The experiment was conducted in SPK-collective farm «Heroi» Chekmagushevsky district in the Republic of Bashkortostan. Group formation was carried out according to the principle of analogues taking into account breed, sex, age and body weight. 4 groups were formed of 6-month-old bull-calves of Black-motley breed and control (I) and 3 experimental (II, III and IV) for 15 heads each. In the diets of young II, III and IV groups in addition to the basic diet were injected with 3.5 g; 7.0 and 10.0 g of probiotic feed additive Biodarin per 1 kg of concentrated feed. Animals treated with the drug at a dose of 7.0 g/kg of concentrated feed, in comparison with their peers of the control group better digested dry matter by 1,64% (P<0.01), organic – 1,25% (P<0.05), crude protein – 2.97% (P<0.05), crude fiber – 1,53% (P<0.05) and BEV – 2.64% (P<0.05). Using in feed rations of large horned livestock young growth feed additive «Biodarin» has positive effect for energy metabolism: energy interchancing increased by 1.02-1.79 per cent, the energy gain is increased by 10.96-of 19.72%.


10.12737/7744 ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 124-127
Author(s):  
Самоделкин ◽  
Aleksandr Samodelkin ◽  
Еремин ◽  
Sergey Eremin

There was studied the distribution of postpartum pathology of cows and disease of calves in early postnatal period in conditions of Nizhny Novgorod region. It was established, that the new tissue drug "bio-tec" has positive influence on reproductive function, safety and live weight gain of calves. The postpartum pathology of cows gained wide spread among nizhnynovgorod farms up to 80%, e.g. Endometritis and subinvolution of uterus 37,4 and 23,9 respectively. By clinical examination of newborn calves it was established, that in the first month of life 50,3% fall ill with gastrointestinal diseases of various etiologies. The die-off of calves reached 29%. Using "bio-tec" drug to dry cows decreased the percentage of postpartum pathology by 35% and reduced the time of involution of uterus for 11,2 days; the service period reduced by 21,2 days and the diseases of newborn calves was twice less, that increased the energy of growth and in 16 month age heifers went over animals of the control group by 10%, that allowed their earlier use for reproduction. So, the results of conducted research showed, that twice a day injection of tissue drug "bio-tec" to dry cows in 10ml dose 60-55 and 40-35 days to calving contributes reducing of obstetric pathology. Subsequent use to calves in 4ml dose in 5-8 days age increases the safety of calves and positively influences the live weight gain, that in fact gives abilities of more effective cattle breeding.


2022 ◽  
Vol 51 (6) ◽  
pp. 68-76
Author(s):  
T. V. Sevastianova ◽  
B. V. Usha

The results of tests of a new combined feed additive Bioprotektin-KD based on milk thistle extract with the addition of a complex of bacteria of the genus Lactobacillus and Bifidobacterium to restore intestinal microbiota of animals are presented. Preclinical studies on the effectiveness of the feed additive were conducted on mice with experimental antibiotic-associated dysbacteriosis. Studies on the intestinal microbiota of mice revealed varying degrees of effect of different doses of feed additive on the recovery of resident microflora. The results of pre-clinical studies have proven the harmlessness, non-toxicity and efficacy of the feed additive. Clinical trials of the additive were carried out on productive animals. Its effect on the productivity of black-motley breed cows in a livestock farm in the Belgorod region was studied. The use of the functional feed additive Bioprotectin-KD had a positive effect on the milk productivity of black-motley breed cows. Cows in the experimental groups that received the feed additive had increased their milk yield per lactation by 209.41-499.01 kg compared to the control animals, which was 4.01-8.78%. The quality indicators of milk have increased. The composition of the microflora of the experimental (feed supplement recipients) and control calves was studied. It was found that the quantitative composition of probiotic flora in the intestines of young calves of the control group remained practically unchanged throughout the experiment. The number of indigeneous microflora (lactobacilli and bifidobacteria) increased in the experimental animals. The content of lactic acid microorganisms in the experimental calves began to increase on day 6 of feed supplementation and reached physiological norm on day 30. The safety index of the product has been calculated. The use of the functional feed additive Bioprotektin-KD in conditions of a livestock complex has improved such production indicators as calf survival, average daily weight gain, and milk productivity of cows in the experimental groups of animals as compared to the control ones.


2020 ◽  
Author(s):  
Roman Wójcik ◽  
Joanna Małaczewska ◽  
Grzegorz Zwierzchowski ◽  
Jan Miciński ◽  
Edyta Kaczorek-Łukowska

Abstract Background A healthy immune system plays a particularly important role in newborns, including in calves that are far more susceptible to infections (viral, bacterial and other) than adult individuals. Therefore, the present study aimed to evaluate the influence of HMB on the chemotactic activity (MIGRATEST® kit), phagocytic activity (PHAGOTEST® kit) and oxidative burst (BURSTTEST® kit) of monocytes and granulocytes in the peripheral blood of calves by flow cytometry.Results An analysis of granulocyte and monocyte chemotactic activity and phagocytic activity revealed significantly higher levels of phagocytic activity in calves administered HMB than in the control group, expressed in terms of the percentage of phagocytising cells and mean fluorescence intensity (MFI). HMB also had a positive effect on the oxidative metabolism of monocytes and granulocytes stimulated with PMA (4-phorbol-12-β-myristate-13-acetate) and Escherichia coli bacteria, expressed as MFI values and the percentage of oxidative metabolism.Conclusion HMB stimulates non-specific cell-mediated immunity, which is a very important consideration in newborn calves that are exposed to adverse environmental factors in the first weeks of their life. The supplementation of animal diets with HMB for both preventive and therapeutic purposes can also reduce the use of antibiotics in animal production.


Author(s):  
O. F. Anufriev ◽  
V. O. Belash ◽  
V. M. Utochkin

Goal of research - the study aims to evaluate the effectiveness and scientifi c basis for the use of osteopathic correction in the treatment of cognitive impairment.Materials and methods. Two groups of patients participated in the study: Group 1 (focus group) included 22 patients with a syndrome of mild cognitive impairment who received medication and osteopathic correction; Group 2 (control group) consisted of 22 patients who received medication only. The groups were comparable in age, sex, and severity of cognitive impairment. All patients observed before and after treatment underwent complex osteopathic and neuropsychological examinations.Results. The study found that the inclusion of osteopathic correction in the treatment of patients with mild cognitive impairment has a positive effect on the dynamics of a number of neuropsychological tests. In particular, there is a statistically signifi cant increase in the indicators based on the results of the Montreal Cognitive Evaluation Scale; there is a decrease in the overall anxiety level based on the results of the Hospital Alarm and Depression Scale. Moreover, the focus group shows a statistically signifi cant decrease in the severity of somatic dysfunction in the head and neck area, both structural and visceral components, which was not observed in the control group.Conclusion. The results from the study suggest recommending the inclusion of osteopathic correction in the complex therapy for patients with mild cognitive impairment.


Author(s):  
Ю.М. СМИРНОВА ◽  
А.В. ПЛАТОНОВ

Изучены особенности пищевого поведения коров-первотелок при скармливании ферментативно-пробиотических препаратов. Для изучения влияния пробиотиков на основе целюлозолитических бактерий рубца жвачных проводился опыт в условиях хозяйства Вологодской области. Были сформированы 3 группы первотелок черно-пестрой породы по 12 голов методом пар-аналогов с учетом кровности, удоя матерей за наивысшую лактацию, живой массы, количества дойных дней после отела и суточного удоя. Животные контрольной группы получали основной рацион,  коровам I опытной группы дополнительно скармливали по 50 г на 1 голову в сутки кормовую добавку на основе целюлозолитических бактерий рубца коров, а II опытной — такое же количество добавки на основе целюлозолитических бактерий рубца оленей. Продолжительность скармливания добавок составляла 90 дней. В результате исследований было установлено, что использование ферментативно-пробиотических препаратов положительно повлияло на пищевую активность и уровень молочной продуктивности первотелок. Коровы I и II опытных групп, получавшие дополнительно к основному рациону ферментативно-пробиотические препараты в сравнении с контрольной группой имели более высокие показатели по затратам времени на потребление корма — 8 и 25 мин., соответственно. Время, затраченное на жвачку, у первотелок II опытной группы было больше на 12 мин., чем у животных контрольной группы, в результате индекс пищевой активности у них был выше на 0,026 по сравнению с контролем. Использование добавок способствовало увеличению молочной продуктивности коров I и II опытных групп, по сравнению с контрольной, на 207 и 151 кг. Полученные результаты подтверждают положительное влияние ферментативно-пробиотических препаратов в кормлении коров, так как они способствуют повышению их пищевой активности и молочной продуктивности. The features of first-born cows’ nutritional behavior when feeding enzyme-probiotic preparations have been studied. To study the effect of probiotics based on the ruminants’ cellulolytic rumen bacteria, an experiment on a farm in the Vologda Oblast has been conducted. There were formed 3 groups of black-and-white first-born cows of 12 heads by the method of pairs-analogues, taking into account pedigree, mothers’ milk yield for the highest lactation, live weight, the number of milking days after calving and daily milk yield. The animals of the control group received the main diet, the cows of the I experimental group were additionally fed 50 g per 1 head per day of a feed additive based on cellulolytic bacteria of cow rumen, and the II experimental group were fed the same amount of an additive based on cellulolytic bacteria of deer rumen. The duration of feeding the additives was 90 days. The research found that the use of enzyme-probiotic preparations had a positive effect on the first-born cows’ nutritional activity and milk productivity level. The cows of the I and II experimental groups who received enzyme-probiotic preparations in addition to the main diet had higher indicators for the time spent on feed consumption in comparison with the control group — 8 and 25 minutes, respectively. The time spent on rumination was 12 minutes longer in the first group of experimental animals than in the control group; as a result, their food activity index was higher by 0.026 compared to the control group. The use of additives contributed to an increase in the milk productivity of cows of the I and II experimental groups, compared with the control group, by 207 and 151 kg. The obtained results confirm the positive effect of enzyme-probiotic preparations when feeding cows, as they help to increase their nutritional activity and milk productivity.


2021 ◽  
Vol 1 (11) ◽  
pp. 64-71
Author(s):  
Regina F. Ivannikova ◽  
◽  
Nikolay V. Pimenov ◽  
Gulnora Sh. Navruzshoeva ◽  
◽  
...  

The article presents the results of studies on the use of a feed additive containing live sporeforming bacteria Bacillus subtilis and live yeast Saccharomyces cerevisiae, sorbed on activated carbon particles, to pregnant cows for the formation of immunoglobulins in the body and their isolation in colostrum, as well as for the nonspecific resistance of the resulting calves. The experiments were conducted in the winter-spring period, when the body of cows and calves contains a reduced level of nutrients, immunoglobulins and other biologically active substances, which leads to inhibition of the function of both nonspecific resistance factors and specific immunity. It was found that the feed additive had a positive effect on the physiological and biochemical parameters of calves. In the colostrum of cows of the experimental groups, relative to the animals of the control group, the content of immunoglobulins was 36.4% higher. Calves whose mothers received a feed additive for 30 days at a dose of 20 g per head before calving had higher indicators of total protein, albumins, globulins and factors of nonspecific resistance, such as bactericidal and lysozyme activity of blood serum, phagocytic activity of neutrophils.


2021 ◽  
Vol 1 (5) ◽  
pp. 57-62
Author(s):  
R. F. Ivannikova ◽  
◽  
N. V. Pimenov ◽  

The article presents the results of studies on the use of synbiotic feed additives based on live spore-forming bacteria of the genus Bacillus, lysates of lactic acid bacteria and yeast to lambs of 10-day-old Volgograd breed in various doses. The use of the feed additive did not have a negative effect on the morphological parameters of the lambs ' blood. Physiological parameters for the entire observation period were within the reference values characteristic of this animal species. The positive effect of synbiotic feed additive was manifested by higher growth rates – an increase in the live weight of the lambs of the experimental groups compared to the control group.


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