TREATMENT OF COWS WITH MASTITIS

Author(s):  
A.Yu. Aliev ◽  

Mastitis of farm animals is widespread and ubiquitous and causes great economic damage to dairy farming. The drugs used do not always give the desired results. The search of new highly effective methods and means of treating of all forms of mastitis of cows is a priority task for scientific and practical veterinarians. The purpose of the work is to study the therapeutic efficacy of a combined antibacterial drug – Tiacycline. The work was carried out on cows of the red-steppe breed with subclinical mastitis in the amount of 35 animals. The drug was administered to the cows of the experimental group intramuscularly, in a dose of 5 ml per 100 kg, every 24 hours during 3-4 days. The animals of the control group were treated with Mastisan A according to the instructions for use. The therapeutic efficacy in the experimental group was 95,0%, the control – 87,0%. Studies have shown that the drug Tiacycline has a high therapeutic efficacy in the treatment of cows with subclinical mastitis, and in future it can be recommended for the treatment of cows with clinical mastitis.

2020 ◽  
pp. 5-17
Author(s):  
A. Yu. Aliev ◽  
B. B. Bulathanov

Relevance. The work is devoted to the results of studying of the antimicrobial and therapeutic efficacy of the drug thiacycline in subclinical mastitis in sheep. The aim of our research еsеwas to study the antimicrobial activity and therapeutic efficacy of thiacycline in subclinical mastitis in lactating ewes.Methods. The study of antimicrobial activity was carried out by the method of serial dilutions in a liquid nutrient medium, on the basis of the Caspian zonal NIVI in the laboratory on the study of diseases of non-infectious etiology of farm animals. The therapeutic efficacy of thiacycline was studied in the SEC "Bukhti" of the Gunib district of Dagestan Republic on ewes of the Dagestan rock, aged from 3 to 5 years, with subclinical mastitis, in the amount of 51 heads. Animals on the basis of analogues were divided into two groups: experience (n = 26), control (n = 25). The animals of the experimental group were treated with thiacycline, the drug was administered intramuscularly, once a day, in dose 0.1 ml/kg. The test combination drug thiacycline developed by VIC. The control group was treated with bicillin-3, in dose 600,000 units per head, with an interval 72 hours.Results. The complex antibacterial drug thiacycline has a wide spectrum and high antimicrobial effect against museum strains and potential causative agents of sheep mastitis. The therapeutic efficacy of thiacycline in the treatment of subclinical mastitis in sheep – 97.0%, which is on 13.0% higher compared to bicillin-3. On the 7th day after the last administratin of preparation all the physicochemical parameters of milk corresponded to the physiological norm.


Author(s):  
B. M. Bhanderi ◽  
Ajay Goswami ◽  
M. R. Garg

Two hundred and fifty five crossbred cows were selected, having a history of sub-clinical mastitis (SCM) and clinical mastitis (CM) in previous lactation. Seventy eight crossbred cows were served as control, and the remaining were fed daily 10 g supplement containing chelated Cu, Zn, Cr, vitamins E and A along with iodine for 4 weeks prior to calving. Milk and blood samples were collected for analysis of SCC, Na, K, Cl, pH, EC, neutrophil count, FRAP activity etc. Out of 177 experimental cows, only 36 (20%) showed signs of SCM and CM with Mastect strip and CMT which was confirmed by SCC in milk (average 7.26x105 cells/ml milk). However, 67 animals (86%) out of 78 in control group were affected by SCM as indicated by the higher SCC in milk (average 10.11x105 cells/ml milk), which was later aggravated to CM. Milk pH, EC, Na and Cl content in milk were higher (P is less than 0.05) in animals affected by SCM than the normal animals. In experimental group, of 141 animals SCC was within the normal range (1.22-2.36x105 cells/ml milk) and no signs of SCM or CM were observed. Milk lactose, protein, SNF and FRAP activity were higher in unaffected as compared to mastitic animals. On supplementation of vitamins and chelated minerals, blood neutrophil count decreased, whereas, immunoglobulin and FRAP activity increased significantly (P is less than 0.05). It was found that feeding vitamins and chelated minerals based supplement during pre-partum period could significantly reduce the incidences of SCM and CM in crossbred cows.


2020 ◽  
Vol 13 (10) ◽  
pp. 2197-2202
Author(s):  
Mohammad Abed Alhussen ◽  
Hamdan Naef ◽  
Yury Anatolyevich Vatnikov

Background and Aim: Respiratory diseases in young cattle are among the significant cattle pathologies that cause considerable economic damage globally. For the treatment of respiratory diseases, coformulated drugs that increase general nonspecific resistance, exhibit adaptogenic and anti-inflammatory properties, and normalize metabolic processes in animals are currently being used. The aim of our study was to investigate the therapeutic efficacy of the complex drug "gentaminoseleferon", used in the treatment of respiratory diseases in calves, especially in Mycoplasma dispar infection. Materials and Methods: The animals were divided into three groups. Calves with the first clinical signs of respiratory pathology were randomly divided into two groups. The first experimental group (n=5) was intramuscularly injected with sulfetrisan at a dose of 5-10 mL/animal once per day for 7 days. The second experimental group (n=5) was given gentaminoseleferon at a dose of 1 mL/10 kg of body weight once per day for 7 days. The drugs were not used in the control group, the "healthy animals (n=5)". Blood samples were taken 10 days before and after treatment and compared between the experimental and healthy calves. The changes in the hematological and biochemical parameters of blood and serum were evaluated. Results: During the recovery process of animals in the experimental groups, a normalization of the hematological and biochemical parameters of blood and serum was noted. Interestingly, in calves of the second experimental group, an increase in the total serum protein content by 2.2% (p<0.05) was recorded in comparison with the first group. The second group, furthermore, showed an increase in Vitamins A, E, and C concentrations by 13.5% (p<0.05), 11.9% (p<0.005), and 15.1% (p<0.0005), respectively, as well as in zinc and iron concentrations by 4.1% (p<0.05) and 9.3% (p<0.0001), respectively. These findings indicate a more pronounced decrease in the inflammatory process in the respiratory system and intensive restoration of metabolism, thereby establishing the high therapeutic efficacy of gentaminoseleferon. Conclusion: Gentaminoseleferon was proven highly effective in the treatment of calves with respiratory illnesses and in restoring homeostasis in the organisms of animals after treatment, as indicated by the normalization of morphological and biochemical blood parameters with a reduction in the recovery time.


2020 ◽  
pp. 15-18
Author(s):  
Inna R. Kilmetova ◽  
◽  
Igor A. Rodin ◽  
Nazira I. Khayrullina ◽  
Nikolay G. Fenchenko ◽  
...  

Summary. The disbalanced feeding and the uneven distribution of micro- and macroelements in the environment leads to a trace element, in particular hypomelanosis. To accelerate the growth and preservation of young farm animals include in the diet of various biological additives and drugs, which include selenium. For stimulation of weight gain in the livestock industry, as well as for the prevention and treatment of pathological processes in addition to micro - and macrouse amino acids, primarily methionine. The aim of this work was to study the influence of composition of DAFS-25+Polizon on morpho-biochemical parameters of blood and functional state of the liver in fattening bulls of black-motley breed in the conditions of the Republic of Bashkortostan. Experiments using were conducted on bull-calves of black-motley breed of the properties in the properties age from 6 to 15 months. The first experimental group during the experiment was additionally given the composition of DAFS-25+Polizon at a dose of 2 mg/kg, the animals of the control group received a standard diet. To assess the impact of the composition DAFS-25+Polizon on metabolism cattle studied morphological and biochemical indicators of blood and conducted histological examination of the liver. It is established that the use of the composition of DAFS-25+Polizon at a dose of 2 mg/kg increases the number of erythrocytes and hemoglobin in the experimental group and reduces the amount of white blood cells. The serum content of total protein, phosphorus and calcium increases in the group of experimental animals. Microscopic examination of the liver revealed no changes in the structure of the organ and hepatocytes in the experimental group, whereas in the control group hemodynamic disorders and dystrophic changes in liver cells were observed. Thus, the use of the composition DAFS-25+Polizon at a dose of 2 mg/kg of live weight in fattening bulls black-and-white breed contributes to the increase of redox processes in the body, stimulation of metabolism, prevent the development of liver disorders of cellular mechanisms of metabolism, optimizes the structure of the liver, which generally provides higher productivity.


Author(s):  
Z. Fedorova

In order to fi ll the existing protein defi ciency in the rations of farm animals in particular dairy cows it is necessary to input feed lupins as widely as possible in crop rotations. Lupin is a very versatile forage crop it can be used in feed as herbage, in the form of haylage, silage, in compound feed as a protein additive, as well as a green manure crop to increase soil fertility. Questions of protein nutrition should be to be quickly resolved, both in the production of protein and in its standardized rational use. Unbalanced protein rations increase feed consumption per unit of production, thereby increasing its prime cost. In the world soya is generally recognized as a protein feed, but in the Kaliningrad region as in most of regions in our country, it does not maturate being a heat-loving crop. Under these environments the inclusion of extruded lupine grain in the composition of energy-protein concentrates for the production of compound feed has become an alternative to replacing expensive soya. The researches have been carried out it the cattle farm of LLC “Temp” in the Guryevsky area in the Kaliningrad region (March-May 2019) on feeding lactating cows energy-protein concentrate from extruded grain of narrow-leaved lupine, fl ax, triticale, subjected to heat treatment on a press extruder. For this purpose two groups of lactating cows of Black-and-White breed (control and experimental) have been formed using the method of pairs of analogs per 11 heads in each. Cows of the control group have received the main ration of the farm, and cows of the experimental group in addition to the main ration have received compound feed with extruded energy-protein concentrate based on lupine. As a result of research, the positive infl uence of energy-protein concentrate based on lupine in compound feed on the dairy productivity of cows has been established. Recipes of concentrate and compound feed with concentrate for lactating cows, the volume of inclusion of components in the concentrate and in the compound feed have been calculated. During the experiment, the milk yield in the experimental group of cows has increased by 62,4 kg or 8,0 %, than in the control group. From the cows of the experimental group the conditional profi t has been received in the amount of 1684,8 rubles per head.


2014 ◽  
Vol 17 (2) ◽  
pp. 365-366 ◽  
Author(s):  
M. Florek ◽  
J. Król ◽  
Z. Staroniewicz ◽  
B. Bażanów

Abstract This study focuses on the effect of parenteral administration of Selenium (Se) and vitamin E on concentration of Se in plasma and the activity of glutathione peroxidase (GPx) in the blood of dairy cows during peripartal period and their effect on the reduction of clinical mastitis. From a 220 individuals Holstein herd in a two-four lactation-gestation cycle the control group (C), 1st (D1) and 2nd (D2) experimental group were selected. Every group consisted of 15 cows in the last phase of the pregnancy. All cows were fed with the diet containing 0.1 mg of Se per kg/DM. The blood samples from vena jugularis were collected approximately 21 days before calving (control sampling), 3 days, 12 days and 21 days after calving. On the day of control sampling and 12 days before calving in D1 group, cows were injected subcutaneously in the sprescapular region with preparation Selevit inj. a.u.v. at the doses of 48.4 mg/head of Se, and 550 IU/head of α-Tocoferol (α-Toc). In D2 group, cows were injected by the same preparation only on 21th day before calving with the same doses of Se and α-Toc. The increase in the concentration of Se in the plasma and activity GPx in blood in D1 group on the 3rd day and 12th day after calving were determined. Increase in plasmatic concentrations α-Toc on 3rd day after calving and reduction of occurrence of clinical mastitis (13.3%) as compared with control group were found


2017 ◽  
Vol 19 (82) ◽  
pp. 77-81 ◽  
Author(s):  
Yu.V. Zhuk ◽  
S.S. Derkach ◽  
O.А. Valchuk ◽  
A.M. Shevchenko

The article presents the results of our own research on the therapeutic effectiveness of the use of FORTICEPT UDDER FORTE for post-milk treatment of cows with subclinical mastitis.As is known, one of the reasons for the emergence of mastitis of cows is the lack of proper sanitary-hygienic treatment of breast milk after milking. Taking into consideration the fact after milking, according to various authors, remains open for 30 minutes to 2 hours, it leads to the infection of the mammary gland with the microflora causing its inflammation.The study of the effectiveness of using FORTICEPT UDDER FORTE after milking treatment of cow's doses was performed in comparison with other existing agents: on the basis of chlorhexidine and iodine.The use of FORTICEPT UDDER FORTE for post-milking treatment of cow's dug reduces their incidence by subclinical mastitis by 30–40%.The therapeutic efficacy of using FORTICEPT UDDER FORTE in cows in the first experimental group was 20.1% higher than the other animals (chlorhexidine-based agent) and 13% in the third group (iodine-based). 


Author(s):  
А.И. Фролов ◽  
А.Н. Бетин

Жизненно важными микроэлементами для жвачных животных являются медь, цинк, марганец, железо, кобальт, йод, селен. Микроэлементы, в которых атом металла соединён и защищён белковыми молекулами, улучшают воспроизводительные качества самок за счёт повышения оплодотворяемости, уменьшения эмбриональной смертности, улучшения состояния мочеполовой системы или повышения интенсивности функционирования яичников. Поэтому в настоящее время актуальными являются разработка и внедрение в технологию кормления сельскохозяйственных животных наиболее эффективных препаратов с необходимыми биологически активными веществами. На основании проведённого исследования дано практическое обоснование использования в технологии кормления тёлок отечественной кормовой биодобавки на основе гидролизата соевого белка, витаминов и микроэлементов. Установлено её положительное действие на некоторые функции органов и систем животных. Экспериментально доказана эффективность её применения для оптимизации обменных процессов и повышения воспроизводительных функций тёлок. Так, биохимическим исследованием образцов крови подопытных животных установлено, что количество кальция и фосфора в крови у тёлок опытной группы по сравнению с контролем было достоверно выше на 2,35 и 2,9% соответственно. Эритропоэтическая фракция была более выражена у молодняка опытной группы. У тёлок опытной группы время от начала скармливания препарата до первой выраженной охоты и осеменения, по сравнению с контрольными животными, сократилось на 16%, а период от начала скармливания препарата до плодотворного осеменения – на 25,7%. Количество тёлок, пришедших в охоту и осеменённых в первый месяц, в опытной группе по сравнению с контрольной было на 43% больше. Оплодотворяемость тёлок опытной группы за учётный период составила 95%, что на 20% больше, чем у животных контрольной группы. Включение в рацион тёлок биодобавки в дозе 100 мл/гол. позволило получить дополнительно на 8,5% больше валового прироста живой массы по отношению к их аналогам. The vital trace nutrients for ruminants are copper, zinc, manganese, iron, cobalt, iodine, selenium. Microelements in which a metal atom is jointed and protected by protein molecules improve the reproductive qualities of females by increasing fertility, reducing embryonic mortality, improving the state of the genito-urinary system or increasing the intensity of ovarian functioning. Therefore the development and implementation of the most effective preparations with the necessary biologically active substances in the technology of feeding farm animals is currently relevant. On the ground of conducted research a practical substantiation of the use of domestic food supplement based on the hydrolyzate of soy protein, vitamins and trace nutrients in the feeding technology of heifers is given. Its positive effect on some functions of animal organs and systems has been established. The effectiveness of its application to optimize metabolic processes and increase the reproductive functions of heifers has been experimentally proven. Thus a biochemical blood samples analysis of experimental animals found that the amount of calcium and phosphorus in the blood of the heifers of the experimental group compared with the control was significantly higher by 2.35 and 2.9% respectively. The erythropoietic fraction was more defined in the young experimental group. In heifers of the experimental group the time from the beginning of feeding the drug to the first defined heat and insemination compared with control animals decreased by 16% and the period from the beginning of feeding the drug to prolific insemination – by 25.7%. The number of heifers that came to the heat and inseminated in the first month in the experimental group was 43% higher than the control group. The impregnation capacity of the heifers of the experimental group during the record period was 95% which is 20% more than in animals of the control group. Inclusion in the diet of heifers bioadditive at a dose of 100 ml / goal allowed obtaining additionally 8.5% more the gross body weight gain relative to their analogs.


Author(s):  
A. Melnyk ◽  
V. Bezukh ◽  
O. Dubin ◽  
V. Moskalenko ◽  
N. Vovkotrub ◽  
...  

In Ukrainian veterinary medicine the study of the eff ectiveness of new complex drugs remains relevant. The eff ect of the vitamin-mineral complex "Alphabet for Animals" on the state of hemocytopoiesis and the microelements metabolism in calves of 1.5‒2.5 months of age were studied. The composition of this drug includes the biologically active substances: vitamins A, D3, E, B1, B3, B5, B6, B12, K3 and essential amino-acids: DL-methionine, L-lysine and arginine. It is used in farm animals and poultry for the normalization of hemocytopoiesis, the prevention and treatment of vitamins and trace elements metabolism’s disorders. In the fi rst week of drug administration, the number of erythrocytes in the experimental animals group has increased signifi cantly (p<0.05) and after its second feeding, the positive eff ect on erythrocytopoiesis in calves has became even greater (p<0.001), compared to the calves in control group. The level of hemoglobin in calves of experimental group also increased signifi cantly from the beginning of the drug to the end of the experiment, whereas in calves of the control group there was a tendency to decrease its level throughout the all experiment. The color index and erythrocyte saturation by hemoglobin (MCH) at the fi rst and second blood samples were signifi cantly decreased (p<0.05) in control calves group, whereas in animals of experimental group there was no signifi cant diff erence between these parameters (p<0.1). The average volume of red blood cells did not diff er between control and test calves during the experiment (p<0.1). Under the drugs infl uence the Ferum blood content in calves of experimental group increased by 24.2 %. In the control calves group, this tendency was not so noticeable (the increase of Ferum serum level at the end of experiment was only +7.8 % (p<0.1), compared to the initial indices). The Zinc metabolism, on the contrary, has not undergone signifi cant changes. The Cuprum serum level in experimental calves group remained always signifi cantly higher than in control animals group. “Alphabet for Animals” has a positive eff ect on hemocytopoiesis in calves due to its complex composition (fat-soluble and water-soluble vitamins, aminoacids) and improves the metabolism of microelements, including Ferum and Cuprum. The infl uence on these processes the vitamins of B group, which are a part of this drug, we consider especially valuable in the conditions of the unformed rumen digestion in young cattle. Key words: vitamin-amino acid complex, erythrocytopoiesis, hypochromia, microcytosis, hemoglobin, color index, hematocrit.


Author(s):  
S. Shpynova ◽  
O. Yadrishchenskaya ◽  
T. Selina ◽  
E. Basova

The development of industrial poultry farming requires not only the breeding of new highly productive poultry breeds, but also the development of new rearing technologies and the improvement of standardized nutrition. Currently, in the field of feeding farm animals and poultry an important research area is the search for cheaper non-traditional and affordable feed products that can replace part of the grain in the poultry diet. It is very important to use local raw materials. One of these crops is naked oat, which has the highest energy content, the highest concentration of lysine and methionine among all cereals. The purpose of the researches was to determine the eff ectiveness of using naked oat in compound feed for quails. The results of the influence of complete nutrient-balanced compound feeds with naked oat on zootechnical and economic indicators in the rearing of quails have been presented in the article. It has been found that the live weight of quails in the experimental group has been increased by 3,06 %, while the average daily feed consumption has been increased by 1,83 %. Feed expenditures per 1 kg of live weight gain in the experimental group have been lower by 1,31 % due to the absorption of feed nutrients. According to the results of the balance experiment, the digestibility of raw protein has increased by 1,90, fat by 0,41 %, nitrogen-free extractive substances by 2,77 %. When calculating economic indicators, it has been found that the use of naked oat in compound feed for quails allowed to increase the yield of meat and revenue from its sale by 3,75 %. Despite an increase in the total cost of feed consumed by the experimental group by 2,27 %, the profi t has been received by 9,59 % more. The level of profi tability of quail meat production in the experimental group exceeded the indicator of the control group by 3,40 %.


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