scholarly journals The Effectiveness of Bioadditive Use in the Diets of Heifers of a Covering Age

Author(s):  
А.И. Фролов ◽  
А.Н. Бетин

Жизненно важными микроэлементами для жвачных животных являются медь, цинк, марганец, железо, кобальт, йод, селен. Микроэлементы, в которых атом металла соединён и защищён белковыми молекулами, улучшают воспроизводительные качества самок за счёт повышения оплодотворяемости, уменьшения эмбриональной смертности, улучшения состояния мочеполовой системы или повышения интенсивности функционирования яичников. Поэтому в настоящее время актуальными являются разработка и внедрение в технологию кормления сельскохозяйственных животных наиболее эффективных препаратов с необходимыми биологически активными веществами. На основании проведённого исследования дано практическое обоснование использования в технологии кормления тёлок отечественной кормовой биодобавки на основе гидролизата соевого белка, витаминов и микроэлементов. Установлено её положительное действие на некоторые функции органов и систем животных. Экспериментально доказана эффективность её применения для оптимизации обменных процессов и повышения воспроизводительных функций тёлок. Так, биохимическим исследованием образцов крови подопытных животных установлено, что количество кальция и фосфора в крови у тёлок опытной группы по сравнению с контролем было достоверно выше на 2,35 и 2,9% соответственно. Эритропоэтическая фракция была более выражена у молодняка опытной группы. У тёлок опытной группы время от начала скармливания препарата до первой выраженной охоты и осеменения, по сравнению с контрольными животными, сократилось на 16%, а период от начала скармливания препарата до плодотворного осеменения – на 25,7%. Количество тёлок, пришедших в охоту и осеменённых в первый месяц, в опытной группе по сравнению с контрольной было на 43% больше. Оплодотворяемость тёлок опытной группы за учётный период составила 95%, что на 20% больше, чем у животных контрольной группы. Включение в рацион тёлок биодобавки в дозе 100 мл/гол. позволило получить дополнительно на 8,5% больше валового прироста живой массы по отношению к их аналогам. The vital trace nutrients for ruminants are copper, zinc, manganese, iron, cobalt, iodine, selenium. Microelements in which a metal atom is jointed and protected by protein molecules improve the reproductive qualities of females by increasing fertility, reducing embryonic mortality, improving the state of the genito-urinary system or increasing the intensity of ovarian functioning. Therefore the development and implementation of the most effective preparations with the necessary biologically active substances in the technology of feeding farm animals is currently relevant. On the ground of conducted research a practical substantiation of the use of domestic food supplement based on the hydrolyzate of soy protein, vitamins and trace nutrients in the feeding technology of heifers is given. Its positive effect on some functions of animal organs and systems has been established. The effectiveness of its application to optimize metabolic processes and increase the reproductive functions of heifers has been experimentally proven. Thus a biochemical blood samples analysis of experimental animals found that the amount of calcium and phosphorus in the blood of the heifers of the experimental group compared with the control was significantly higher by 2.35 and 2.9% respectively. The erythropoietic fraction was more defined in the young experimental group. In heifers of the experimental group the time from the beginning of feeding the drug to the first defined heat and insemination compared with control animals decreased by 16% and the period from the beginning of feeding the drug to prolific insemination – by 25.7%. The number of heifers that came to the heat and inseminated in the first month in the experimental group was 43% higher than the control group. The impregnation capacity of the heifers of the experimental group during the record period was 95% which is 20% more than in animals of the control group. Inclusion in the diet of heifers bioadditive at a dose of 100 ml / goal allowed obtaining additionally 8.5% more the gross body weight gain relative to their analogs.

Author(s):  
I. Ivanova ◽  
Yu. Karmatskikh

When balancing ration it is necessary to remember that the active factors of feeding are not the feed itself, but the content of nutrients and biologically active substances in them. It has been developed and physiologically justified feeding rations of cows during increasing the milk yield period, which are based on succulent feed, hay, grain and rapeseed presscake and a source of minerals and vitamins PVMA have been used. The experimental part of the work has been carried out in the winterstall period in the educational and experimental farm in the State Agrarian University of the Northern Trans-Urals. It has been found that from cows of the experimental group during the increasing the milk yield period 1503 kg of milk containing 3,98 % fat and 2,87 % protein has been obtained. Animals of the experimental group exceeded cows of the control group in milk yield by 90 kg (P > 0,95), in terms of fat and protein content in milk their superiority was 0,37 abs.% (P > 0,999) and 0,21 abs.% (P> 0,999). Input into the rations of lactating cows rapeseed presscake in the amount of 2 kg/ head/day and PVMA in the amount of 100 g during 3 months of lactation gives an increase in productivity for the entire lactation in the experimental group by 572 kg of milk with additional products by 2745,2 Rubles can be obtained more. The positive effect of the input of rapeseed presscake in the rations of lactating cows in the amount of 2 kg/head has been established/day and PVMA in the amount of 100 g in the period of following on the subsequent productivity of animals.


Author(s):  
B. S. Kaloev ◽  
M. O. Ibragimov ◽  
M. M. Shagaipov

The reliability of the results obtained in scientific and economic experiments on the study of the effectiveness of the use of various feed components, including biologically active substances in the rearing of broilers needs to be confi rmed in production conditions. The purpose of the research was to study the joint use of enzyme drugs and lecithin in the rearing of broiler chickens. The results of production experiment on the study of the effectiveness of the joint inclusion of enzyme drugs Sunzyme and Sunfyse 5000 as well as lecithin in the diet of broiler chickens of the cross Ross-308 have been presented in the article. Production tests have been carried out under the conditions of the breeding farm “Achkhoy– Martanovsky” in the Chechen Republic. The duration of the experiment was 45 days. For research on the principle of analog groups two groups have been formed: a control group and an experimental group of 1000 heads in each. The broilers of the control group have been fed compound feed prepared in accordance with the growing period and consisting mainly of grain components of local production. The broilers of the experimental group have been fed the same compound feed, but with the addition of two enzyme drugs Sanzyme and Sanfyse 5000 (100 g/t of feed) as well as lecithin (10 g/kg of feed). The results of the production experiment fully confi rmed the data obtained in the scientific and economic experiment. The positive effect of the joint use of the studied enzyme drugs and lecithin has been manifested in all the studied productive traits. In particular, the increase in live weight of broilers increased by 12,1 %, slaughter yield by 3,5 %, the yield of carcasses of the 1st category by 3,0 %. The main economic indicators also found their confirmation: feed consumption per unit of growth decreased by 11,7 %, additional profit was received in the amount of 27308,2 rubles, the level of profitability of broiler rearing increased by 18,4 %.


2019 ◽  
pp. 69-72
Author(s):  
Olga Nikolaevna Polozyuk ◽  
Tatyana Ivanovna Lapina

The authors found out that the application  of dietary supplements "Glimalask Lact" allowed preventing the disorder of the gastrointestinal tract and saving all piglets throughout the experiment.  After application of "Agrocid super oligo", the safety of purebred piglets was 100 %, and for two pedigree piglets it was 96.7%.   In piglets of the 1st and 2nd control groups, disorder of the gastrointestinal tract was noted during the completion of colostral immunity and at weaning from sows.  The safety of purebred piglets was 96.7%, and of the two pedigree piglets  it was 93.4%. The number of γg-globulins in the blood serum of two breed piglings treated with the Glimalask Lact supplement increased by 3.5 and 2.5% compared to the piglets of the experimental group fed with Agrocid super oligo, and of the control group, The number of g-globulins in the blood serum of purebred  piglets it increased by 2.4 and 3.1% compared with analogues of the experimental and control groups.


Author(s):  
I.V. Tsiganenko ◽  
L.K. Ovcharenko

The work considers the causes of the coronary X syndrome development in women by assessing the experimental group and the control group with typical angina pectoris with angiographically altered vessels. Each group included 30 patients. When studingy medical records of the patients in the study group, we found out that in the reproductive period all of them had hyperestrogenemia, confirmed by the laboratory data, with the corresponding consequences in the form of various gynecological diseases, while the patients of the control group had unburdened gynaecological history. In terms of the lipid spectrum, the results turned out to be opposite. In the experimental group, the rates were within the normal range, and the control level of LDL-C significantly exceeded the required values. Despite the fact that estrogens increase the concentration of high density lipoprotein (HDL) in the blood and lower the content of low density lipoprotein (LDL) that are atherogenic, their surplus has a less negative effect than their lack, as the risk of developing atherosclerosis increases with decreasing concentration, and with an increase there is a risk of developing endothelial dysfunction, which provokes the development of coronary syndrome X. These date confirm the development of endothelial dysfunction in the patients of the experimental group with hyperestrogenemia in the history resulted from the impairment of the process of proliferation of endothelial cells with subsequent imbalance of secretion of biologically active substances. Among them, there is nitric oxide, which causes the relaxation of smooth myocytes, thus resulting in vasodilatation, and endothelins, providing the opposite, vasodilating effect. Prostacyclines and thrombomodulins secreted by the vascular endothelium in physiological conditions, counteract platelet aggregation. In the case of damage to the vascular wall, the production of prostacyclin and thrombomodulin is suppressed, but the release of thromboplastin, platelet activation factor and von Willerband factor activates that promote platelet aggregation and blood clotting. Under the participation of other physiologically active substances, selectins, endothelial cells promote adhesion to their surface and further penetration into the site of inflammation of neutrophils, blood acidophils. Selectin is accumulated in the cytoplasm of the endothelial cells in the form of specific electron-cellular inclusions, the so-called bodies of Weibel-Palade. Normally, vascular endothelium is impervious to blood components. However, being affected by a number of factors, and in particular histamine, endothelial cells lose contact with each other and decrease in number. This leads to the release of water and plasma proteins into the intercellular medium causing oedema. Due to the ability of the inner layer of vessels to produce a large number of biologically active substances, such changes can hardly be corrected by therapy.


Author(s):  
A. Melnyk ◽  
V. Bezukh ◽  
O. Dubin ◽  
V. Moskalenko ◽  
N. Vovkotrub ◽  
...  

In Ukrainian veterinary medicine the study of the eff ectiveness of new complex drugs remains relevant. The eff ect of the vitamin-mineral complex "Alphabet for Animals" on the state of hemocytopoiesis and the microelements metabolism in calves of 1.5‒2.5 months of age were studied. The composition of this drug includes the biologically active substances: vitamins A, D3, E, B1, B3, B5, B6, B12, K3 and essential amino-acids: DL-methionine, L-lysine and arginine. It is used in farm animals and poultry for the normalization of hemocytopoiesis, the prevention and treatment of vitamins and trace elements metabolism’s disorders. In the fi rst week of drug administration, the number of erythrocytes in the experimental animals group has increased signifi cantly (p<0.05) and after its second feeding, the positive eff ect on erythrocytopoiesis in calves has became even greater (p<0.001), compared to the calves in control group. The level of hemoglobin in calves of experimental group also increased signifi cantly from the beginning of the drug to the end of the experiment, whereas in calves of the control group there was a tendency to decrease its level throughout the all experiment. The color index and erythrocyte saturation by hemoglobin (MCH) at the fi rst and second blood samples were signifi cantly decreased (p<0.05) in control calves group, whereas in animals of experimental group there was no signifi cant diff erence between these parameters (p<0.1). The average volume of red blood cells did not diff er between control and test calves during the experiment (p<0.1). Under the drugs infl uence the Ferum blood content in calves of experimental group increased by 24.2 %. In the control calves group, this tendency was not so noticeable (the increase of Ferum serum level at the end of experiment was only +7.8 % (p<0.1), compared to the initial indices). The Zinc metabolism, on the contrary, has not undergone signifi cant changes. The Cuprum serum level in experimental calves group remained always signifi cantly higher than in control animals group. “Alphabet for Animals” has a positive eff ect on hemocytopoiesis in calves due to its complex composition (fat-soluble and water-soluble vitamins, aminoacids) and improves the metabolism of microelements, including Ferum and Cuprum. The infl uence on these processes the vitamins of B group, which are a part of this drug, we consider especially valuable in the conditions of the unformed rumen digestion in young cattle. Key words: vitamin-amino acid complex, erythrocytopoiesis, hypochromia, microcytosis, hemoglobin, color index, hematocrit.


Author(s):  
М.В. ЛУКЬЯНЕНКО ◽  
Р.В. КАЗАРЯН ◽  
Т.В. ВАНИЦКАЯ ◽  
Е.В. КУЗЬМИНОВА ◽  
М.П. СЕМЕНЕНКО ◽  
...  

Для интенсификации производства животноводческой продукции и повышения ее качества необходимо обогащать рацион сельскохозяйственных животных и птицы кормовыми добавками, содержащими комплекс биологически активных веществ. Исследованы образцы комплексной кормовой добавки, содержащей масляную композицию БАВ в-каротина, витаминов Е и С, жидкого рапсового лецитина и селена, и пробиотическую добавку (ПД) Целлобактерин в соотношениях соответственно от 1 : 1 до 1 : 5. Установлено, что при соотношении масляная композиция БАВ : ПД Целлобактерин 1 : 3 количество пробиотической культуры Enterococcus faecium 1-35, содержащейся в ПД Целлобактерин, в опытном образце достигает максимального значения 6,4 Ч 105 КОЕ/г. При этом обеспечивается равномерное распределение масляной композиции БАВ на поверхности ПД. В опытах in vivo определена эффективность применения комплексной добавки с установленным соотношением компонентов для нормализации обменных процессов в организме животных. Доказано, что введение в рацион лабораторных крыс опытной группы многокомпонентной кормовой добавки в количестве 3 к основному рациону (ОР), контаминированному микотоксинами, позволяет достичь опережения прироста массы тела на 15-е и 45-е сутки эксперимента на 6,45 и 33,05 соответственно снижения содержания мочевины в сыворотке крови на 58,43 по сравнению с аналогичными показателями у животных контрольной группы, получавших только ОР. Степень снижения аланинаминотрасферазы и аспартатаминотрансферазы по отношению к аналогичным показателям контрольной группы составила 18,53 и 29,89 соответственно. Следовательно, комплексная кормовая добавка при соотношении масляная композиция БАВ : ПД Целлобактерин 1 : 3 обладает ярко выраженными гепатопротекторными и антитоксическими свойствами. Enriching the diet of farm animals and poultry by feed additives containing a complex of biologically active substances is necessary to intensify the production of livestock products and improve their quality. Samples of a complex feed additive containing an oil composition of BAS в-carotene, vitamins E and C, liquid rapeseed lecithin and selenium, and a probiotic additive (PA) Cellobacterin in ratios from 1 : 1 to 1 : 5 respectively were studied. It was found that the ratio of the oil composition of BAS : PA Cellobacterin 1 : 3 respectively the amount of probiotic culture Enterococcus faecium 1-35 contained in PA Cellobacterin in the experimental sample reaches a maximum value 6,4 Ч 105 CFU/g. In this case, the distribution of BAS oil composition on the PA surface is uniform. The effectiveness of using a complex additive with a set ratio of components to normalize metabolic processes in animals was determined in in vivo experiments. It is established that introduction in a diet of laboratory rats of the experimental group multicomponent feed additive in an amount of 3 to the basic ration (BR), contaminated with mycotoxins, can achieve compared to the same indicators in animals of the control group who received only the BR, the timing of weight gain on 15-th and 45-th day of the experiment by 6,45 and 33,05 respectively reduction of urea content in blood serum at 58,43. The degree of reduction of alanine aminotransferase and aspartate aminotransferase in relation to similar indicators of the control group was 18,53 and 29,89 respectively. Therefore, a complex feed additive with the ratio of oil composition of BAS : PA Cellobacterin 1 : 3 has pronounced hepatoprotective and antitoxic properties.


2020 ◽  
pp. 3-5
Author(s):  
Aleksandr I. Petenko ◽  
◽  
Nikita I. Petenko ◽  
Artem B. Vlasov ◽  
Natalya A. Yurina ◽  
...  

Aim of the research was to study the effect of premix with buffering properties in diets for newborn cows on their milk production, blood biochemical composition, microbiological parameters of scar fluid and its acidity. The experiment was carried out on 2 groups of calving black-motley cows, selected on the basis of the pair-analogue principle with 6 animals each. The first, control group of cows received a ration adopted on the farm. The second group of animals received the same diet, only instead of 0.5 kg of compound feed they used a multicomponent mineral premix enriched with biologically active additives, which has buffering properties, which is very important in the newborn period of cows. Feeding premix with buffering properties in the composition of the main diet to newborn cows contributed to an increase in the consumption of dry matter by animals. Since the cows of the second experimental group consumed more nutrients, a significant increase in the average daily milk yield was found. The studied premix helped establish a tendency to improve metabolic processes in the body of ruminants. In a scientific experiment, a positive effect of the buffer premix on the microbiological parameters of scar fluid, as well as its acidity and acid-binding ability, was established. The consumption of more nutrients was due to a significant increase in average daily milk yields by 9.1%. The results of biochemical studies of blood serum allow us to say that all indicators characterizing the metabolism were within the physiological norm in cows of both groups. Also, a qualitative change for the better in the microbiological parameters of scar fluid was noted. Feeding the studied premix to experienced animals contributed to the additional profit of 4069.8 rubles per head.


Author(s):  
А.В. МИШУРОВ

Проблема и цель. Для повышения эффективности использования питательных веществ кормов целесообразно применение биологически активных веществ (БАВ), способствующих улучшению физиологических процессов в организме животных для реализации их генетического потенциала – продуктивности. Целью исследований являлось изучить влияние БАВ (дигидроквертицина и органического йода) на рубцовый метаболизм у овец. Методология. Опыт проведен методом групп периодов в условиях физиологического двора ФНЦ ВИЖ имени Л.К. Эрнста, на овцах аналогах (n=6), имеющих хронические фистулы рубца по Басову. Животные 1-й опытной группы в дополнение к основному рациону получали 100 мл ДКВ, в рацион 2-й опытной группы добавляли 100 мг ДКВ и 1,05 мг органического йода. Результаты. Использование добавок в рационах животных опытных групп повлияло на общее содержание микроорганизмов в рубцовой жидкости, составившее во второй опытной группе 1,021 г/100 мл, что выше чем в первой опытной группе на 12,7 %, и выше, чем в контрольной, на 15,4 %. При этом образование бактерий в рубцовой жидкости в первой опытной группе было выше на 22,5 %, а во второй – на 8,7 % относительно контроля. Выявлен более низкий уровень концентрации аммиака в содержимом рубца животных первой опытной группы на 4,2 мг/% относительно контрольной и на 7,1 мг/% – второй опытной группы, что взаимосвязано с более эффективным его использованием рубцовой микрофлорой. Заключение. Полученные данные свидетельствуют о том, что использование в рационе изучаемых биологически активных веществ способствовало наибольшему развитию и жизнедеятельности микроорганизмов рубца и в целом способствовало регуляции положительной динамики рубцового метаболизма, оказало положительное влияние на образование и усвояемость азота. Problem and purpose. To increase the efficiency of the use of feed nutrients, it is advisable to use biologically active substances that contribute to the improvement of physiological processes in the body of animals for the realization of their genetic potential - productivity. The aim of the research was to study the effect of biologically active substances (dihydroquerticin and organic iodine) on rumen metabolism in sheep. Methodology. The experiment was carried out by the method of groups of periods in the conditions of the physiological yard of L.K. Ernst Federal Research Center for Animal Husbandry), on sheep analogs (n=6) with chronic rumen fistulas according to Basov. Animals of the 1st experimental group received 100 ml of DHQ in addition to the main diet. The 2nd experimental group got 100 mg of DHQ and 1.05 mg of organic iodine. Results. The use of additives in the diets of the animals of the experimental groups influenced the total content of microorganisms in the rumen fluid, which was 1.021 g / 100 ml in the second experimental group, that was higher than in the first experimental group by 12.7 %, and in the control group by 15.4 %. At the same time, the formation of bacteria in the rumen fluid in the 1st experimental group was 22.5 % higher and it was 8.7 % higher in the 2nd group relative to the control. A lower level of ammonia concentration in the rumen of animals of the 1st experimental group was 4.2 mg/% lower relative to the control and by 7.1 mg/% in the 2nd experimental group, that was interrelated with its more effective use of rumen microflora. Conclusion. The data obtained indicated that the use of the studied biologically active substances in the diet promoted the greatest development and vital activity of rumen microorganisms and, in general, contributed to the regulation of the positive dynamics of rumen metabolism, had a positive effect on the formation and assimilation of nitrogen.


2021 ◽  
Vol 2021 (1) ◽  
pp. 55-64
Author(s):  
Nikolay Gaponov

This paper presents the results of experimental studies the influence of biologically active substances of propolis on micromorphometric parameters of the ileum in young pigs. The results of the experiment make it possible to ascertain a change in the functional activity of the studied organ after the use of the drug from propolis. Since the most active process of absorption of monomeric hydrolysis products, especially amino acids and carboxylic acids, occurs in the ileum. Hydrolysis of intermediate products to monomers and preparation of the transition to absorption is carried out by enzymes fixed on the intestinal cell membranes. And the level of bioconversion of feed and retention of nutrients depends on their shape and structure, which ultimately affects the payment for feed with products. Therefore, the study of the histology of the small intestine and especially the ileum is of great importance. So, as a result of the study, it was found that the most characteristic histological changes in the structural components of the intestinal wall are observed in young animals of the experimental groups. The thickness of the main lamina of the mucous membrane of the ileum in piglets in the control group is 308.28 ± 2.81 µm, in piglets in the experimental group – 255.49 ± 0.75 µm. The height of the villi of the ileum, in the animals of the control group, is significantly lower and amounts to 193.89 ± 2.66 µm versus 280.97 ± 3.37 µm in the experimental group. Similar changes are observed in young animals of the older age group. The height of intestinal villi in pigs of the experimental group significantly exceeds the indicator of the control group and is 256.89 ± 1.62 µm and 163.96 ± 0.61 µm, respectively. The muscle plate of the intestinal mucosa of the pigs in the experimental group is significantly thicker than the control and is 17.8 ± 0.2 μm and 8.89 ± 0.08 μm, respectively. The obtained experimental material substantially supplements the information on the biological properties of propolis preparations. In practical veterinary medicine, research results can be taken into account when prescribing propolis for medicinal and prophylactic purposes. Since histological analysis of intestinal sections did not reveal destructive or pathological changes in any of the compared groups. In feeding, using the obtained practical material, we can specify the stimulating effect of the propolis preparation to intensify the growth of animals depending on the age of the pigs.


2022 ◽  
Vol 42 ◽  
pp. 01027
Author(s):  
Alexey Trebukhov ◽  
Elena Shaganova ◽  
Yulia Chekunkova ◽  
Nadezhda Momot ◽  
Yulia Kolina

Use of biologically active additives in feeding young animals is the most important element of resource-saving technologies. The aim of the study was to study the effectiveness of use of vitamin and mineral nutrition on the growth and development of young animals. 3 groups of calves were formed at the age of 10 days. Animals of the control group received the basic diet (OR), the II-experimental group received OR + salts of microelements and the calves of the III-experimental group received OR + salts of microelements and tetratwit in doses from 1 to 3 months – 1.5 mg, from 3 to 5 months – 2.0 mg and from 5 to 6 months – 3.0 mg. Tetravit was injected once every 2 weeks throughout the study. It was found that feeding the salts of microelements (copper, zinc, cobalt, manganese, iodine) to calves during the dairy period contributes to their more intensive development and growth of their meat productivity, both in combination with tetravite and without it. Use of salts of microelements separately, and in combination with a multivitamin preparation (tetravit) contributes to a significant increase in the studied hematological parameters in young animals, relative to control analogues.


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