scholarly journals Assessment of awareness of Andropause Induced Osteoporosis and measurement of Serum Calcium levels in Men of different age groups

2020 ◽  
Vol 11 (3) ◽  
pp. 25-29

Background: Andropause is under-emphasized in our population, and evidence is scarce on this male health problem. Objective: To assess the andropause awareness and serum calcium level estimation in men who are at a high risk of developing osteoporosis due to age-related androgen deficiency. Methodology: This cross-sectional study was conducted on 100 adult men from November-2018 to February-2019. The awareness collection tool was a structured questionnaire comprising of sociodemographic variables and questions which explored the awareness of osteoporosis due to andropause. Serum calcium levels were also measured in different age groups. Data collected were analyzed by Statistical Package for the Social Sciences (SPSS) version-20. Results: Overall 51% of men were aware of the term andropause while the percentage of the participants who believed that andropause may be the underlying cause of osteoporosis in advancing age was only 26.6%. Serum calcium showed a negative correlation with advancing age (Pearson correlation coefficient, r-value: -0.58). Conclusion: Though more than half of the men were aware of the knowledge of andropause they lack the awareness that osteoporosis might occur due to androgen deficiency. Moreover, decreased serum calcium levels were also observed with advancing age.

2019 ◽  
Vol 08 (04) ◽  
pp. 136-141
Author(s):  
Kafeel Hussain A. ◽  
Shaweez Fathima S. ◽  
V. Sathialakshmi

Abstract Background Although some age-related changes in lymph node histoarchitecture have been described, they are seldom taken into account in traditional depictions of lymph nodes. Recently introduced clinical procedures, such as intranodal vaccinations have demonstrated the need for an accurate knowledge of the degenerative processes of lymph nodes. It is thus deemed necessary to obtain a detailed insight into anatomical changes within the lymph node throughout life as age-related degeneration can have a strong impact on the outcome of these new therapeutic strategies. Aim To study the size and shape of the lymph nodes and to establish the age-dependent histoarchitectural changes in the lymph nodes in different age groups. Materials and Methods A cross-sectional study was conducted in a total of 35 axillary lymph nodes. The adult axillary group of lymph nodes were from subjects aged between 18 and 70 years. The fetal lymph nodes were collected from 8 stillborn fetuses between 37 and 42 weeks. Thickness of the cortex and diameter of the germinal centers were measured using ocular and stage micrometer. Results None of the fetal lymphocytic follicles showed evidence of a prominent germinal center. The germinal centers of young adults were not only more numerous but also larger in size when compared with the old. An age-related involution of the paracortical region was witnessed in the axillary lymph nodes. No evidence of lipomatous atrophy was encountered in any of the fetal lymph nodes. Interesting evidence of it was encountered in younger age groups. However, this was the most prominent feature in the older groups.


1970 ◽  
Vol 1 (1) ◽  
pp. 35-38 ◽  
Author(s):  
P Bastola

Background: There is a lack of study in the pattern of ocular morbidity in western hilly region of Nepal. Therefore a study was carried out to find out the pattern of ocular morbidity, in various age groups in a diagnostic, screening and treatment camp (DST) held in a western hilly remote region of Nepal. Methods: A descriptive, cross sectional study was done to find out the pattern of ocular morbidity in a western hilly region of Nepal. All the cases included in the study were examined thoroughly from Ophthalmological perspective and a diagnosis was made. Patients needing treatment both medical as well as surgical were advised accordingly and referred when indicated. Results: A total of 712 eyes of 356 cases were examined in this study. The range of the age varied from two months of life to 91 yrs of age. Age wise most number of cases were in the school going age group accounting for almost 80% of all the cases. The commonest ocular morbidity encountered were refractive error (15.4%), dry eyes, ocular allergy, followed by cataract. Majority of the cases had both dry eyes and ocular allergy. While 70 eyes of 35 patients had no ocular morbidity. Conclusion: The lower prevalence of age related cataract was due to the extensive cataract surgical coverage provided in the region by various organizations and because of lesser number of cases examined above the age of 40 years. Finding of just three cases of Xerophthalmia (X2B), pointed out towards the success of extensive Vitamin A supplement program run by the ministry of health. Keywords: Refractive error; dry eyes; ocular allergy; cataract DOI: http://dx.doi.org/10.3126/njms.v1i1.5795   Nepal Journal of Medical Sciences. 2012; 1(1): 35-38


2006 ◽  
Vol 72 (2) ◽  
pp. 1027-1033 ◽  
Author(s):  
Susanne Mueller ◽  
Katiana Saunier ◽  
Christiana Hanisch ◽  
Elisabeth Norin ◽  
Livia Alm ◽  
...  

ABSTRACT A cross-sectional study on intestinal microbiota composition was performed on 230 healthy subjects at four European locations in France, Germany, Italy, and Sweden. The study participants were assigned to two age groups: 20 to 50 years (mean age, 35 years; n = 85) and >60 years (mean age, 75 years; n = 145). A set of 14 group- and species-specific 16S rRNA-targeted oligonucleotide probes was applied to the analysis of fecal samples by fluorescence in situ hybridization coupled with flow cytometry. Marked country-age interactions were observed for the German and Italian study groups. These interactions were inverse for the predominant bacterial groups Eubacterium rectale-Clostridium coccoides and Bacteroides-Prevotella. Differences between European populations were observed for the Bifidobacterium group only. Proportions of bifidobacteria were two- to threefold higher in the Italian study population than in any other study group, and this effect was independent of age. Higher proportions of enterobacteria were found in all elderly volunteers independent of the location. Gender effects were observed for the Bacteroides-Prevotella group, with higher levels in males than in females. In summary, age-related differences in the microbiota makeup were detected but differed between the study populations from the four countries, each showing a characteristic colonization pattern.


2021 ◽  
Vol 9 ◽  
Author(s):  
Yiwen Zhang ◽  
Xiao-Dan Wang ◽  
Yehua Song ◽  
Ruiqiang Peng ◽  
Ting Tang ◽  
...  

Background: Frequent/urgent urination is an event of multifactorial origin where involuntary leakage of urine occurs. Epidemiological study of this condition is of high importance due to its negative impact on the psychological, physical, and social well-being of the victims.Objective: This cross-sectional study aimed to investigate the prevalence of frequent/urgent urination in older adults in China.Method: In this study, a face-to-face questionnaire survey was conducted between April 2019 and August 2019 among 4,796 older adult populations in the communities of Tianjin jizhou and Xiamen jimei of China. Descriptive analysis, univariate regression, and all statistics were conducted in IBM SPSS v22. The count data were analyzed by chi-square test. P < 0.05 was considered statistically significant.Results: In the total investigated population, the prevalence of frequent or urgent urination was found in 1,164 patients (24.3%) where 31.7% (664/2,097) were male patients and 18.7% (500/2,699) were female patients, having a male-to-female ratio of 1.7:1. The prevalence was higher in the 70- to 84-year-old group (men: 33.3–34.8%, women 19.5–20.8%), whereas it was relatively low in the 65- to 69-year-old group and in older adults over 85 years of age (men 28.8, 30.3%, women 16.7, 18.5%, respectively). In terms of the course of the disease, among the population aged 65 years and above, 17.3% men and 9.9% women had frequent urination/urgency lasting for 1–4 years; 5–9 years in about 4.5% population (7.4% men and 4.2% women); 10–19 years in 4.9% men and 2.3% women; and more than 20 years duration in 1.6% men and 1.9% women. On the severity scale, mild frequent/urgent urination was observed in 24.6% of men and 15.4% women of Chinese older adults. Moderate cases were observed in 6.3% of men and 2.9% of women, whereas severe cases were found in 0.8% men and 0.2% women. Benign prostatic hyperplasia (BPH)/hypertrophy was the main risk factor for frequent/urgent urination in Chinese older adult men (P < 0.001). Obesity, hypertension, diabetes, heart disease, anxiety, depression, constipation, and brain injury were the other risk factors for frequent/urgent urination in Chinese older adult men and women. The results of this survey showed that smoking or drinking habits did not increase the prevalence of frequent/urgent urination in Chinese older adults.Conclusions: According to the results of this survey, the prevalence rate of frequent/urgent urination is high, and the course of the disease is long in Chinese older adults. BPH and depression, anxiety, and age-related chronic diseases increase the risk of frequent/urgent urination in Chinese older adults.


BMJ Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. e034226
Author(s):  
Lei Feng ◽  
Shiyan Nian ◽  
Zongwu Tong ◽  
Ying Zhu ◽  
Ying Li ◽  
...  

ObjectivesThis study aimed to investigate the dynamic trends in total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) levels with ageing.DesignA Chinese population-based cross-sectional study.SettingA physical examination centre of a general hospital.ParticipantsAdult subjects (178 167: 103 461 men and 74 706 women) without a known medical history or treatments that affect lipid metabolism.Main outcome measuresDynamic trends in the above-mentioned lipid parameters with ageing were explored; turning points of age were established using age stratification and validated by fitted multivariate linear regression modelling.ResultsAge was found to be an independent factor extensively associated with lipid levels in both sexes when adjusted for serum glucose, body mass index, lifestyle, drinking and smoking. Age was positively associated with TC, logarithm-transformed TG (LnTG) and LDL-C levels in men ≤40, ≤40 and ≤60 years old (yo) and in women ≤60, ≤70 and ≤60 yo, respectively. Conversely, age correlated negatively with TC, LnTG and LDL-C levels in men ≥61, ≥41 and ≥61 yo and in women ≥61, ≥71 and ≥61 yo, respectively. TC, TG and LDL-C levels in women were initially lower than those in men but surpassed those in men in 51–55, 61–65 and 51–55 yo age groups. The trends in HDL-C levels with age were relatively irregular, although HDL-C levels in women were higher than in men for all age groups.ConclusionsThe definition of dyslipidaemia, the atherosclerotic cardiovascular disease risk assessment and the initiation/goals of statin therapy should fully consider age-related trends in lipid levels and sex differences.


2002 ◽  
Vol 26 (1) ◽  
pp. 60-69 ◽  
Author(s):  
Christophe Mouchiroud ◽  
Todd Lubart

We assessed children’s social creativity through interviews during which participants imagined original solutions to interpersonal problems. In addition, we compared performances in the social domain with those obtained in object-oriented problem-solving tasks such as the Unusual Uses of a Box creativity test designed by Torrance (1974) and the Similarities subtest of the WISC (1996). A total of 88 French children participated in this study. First, we observed links between social creativity tasks as well as consistent developmental trends showing that social creativity can be considered as a unitary construct. Second, with regard to the integration or differentiation of creative abilities in children’s development, results showed a distinct creative ability in the social domain for younger children and the emergence of a more general creative ability in older children. Third, the relationship between fluency and originality indices was stable across age groups and task domains, supporting Simonton’s constant-probability-of-success model (1990) for children. Implications for the study of creative abilities in the social domain and for understanding how children interact with others in various social settings are discussed.


Author(s):  
Syed Amar Gilani ◽  
Iqra Manzoor

ABSTRACT Objective To ascertain that acrania can lead to anencephaly Materials and methods We commenced a cross-sectional study for a period of 41 months from 2013 to 2017. During routine ultrasound examination, we observed multiple cases of acrania in second trimester and third trimester. We followed 26 cases who failed to terminate their pregnancies and visited for reexamination. Changes in the brain matter, amniotic fluid volume, and echogenicity of the acrania fetuses were recorded and compared with the previous examination. Development of anencephaly was correlated with maternal age and advancement of gestational age. All the patients were examined transabdominally according to the American Institute of Ultrasound in Medicine (AIUM) guidelines for obstetrical ultrasound. Data were collected from the previous report and recent examination, by evaluating data with the help of IBM Statistical Package for the Social Sciences (SPSS) version 24 package, and the results were summarized. Results Pregnant women with diagnosed acrania fetus visited second time with a lapse of more than 4 weeks and were enrolled with mean age 25.73 ± 8.80. We observed 4 (15.4%) acrania patients developed into anencephaly. Development of anencephaly was observed to be correlated with the advancement of gestational age. It was observed that acrania is more common in below 20 and above 30 age groups. Haziness of amniotic fluid is also observed to be related with acrania. Conclusion Anencephaly could be caused by multiple factors but acrania can lead to anencephaly with continuous exposure of brain matter and meninges to mechanical trauma and chemical activities of the amniotic fluid. Clinical significance To test the hypothesis of acrania to anencephaly and make a roadmap for upcoming researches on association of acrania with physical, environmental, and genetical factors. How to cite this article Bacha R, Gilani SA, Manzoor I. Sonographic Transformation of Acrania to Anencephaly. Donald School J Ultrasound Obstet Gynecol 2017;11(3):189-196.


2021 ◽  
Vol 12 ◽  
Author(s):  
Claire V. Burley ◽  
Susan T. Francis ◽  
Kate N. Thomas ◽  
Anna C. Whittaker ◽  
Samuel J. E. Lucas ◽  
...  

Cerebrovascular reactivity (CVR) is used as an outcome measure of brain health. Traditionally, lower CVR is associated with ageing, poor fitness and brain-related conditions (e.g. stroke, dementia). Indeed, CVR is suggested as a biomarker for disease risk. However, recent findings report conflicting associations between ageing or fitness and CVR measures. Inconsistent findings may relate to different neuroimaging modalities used, which include transcranial Doppler (TCD) and blood-oxygen-level-dependant (BOLD) contrast magnetic resonance imaging (MRI). We assessed the relationship between CVR metrics derived from two common imaging modalities, TCD and BOLD MRI, within the same individuals and with expected significant differences (i.e., younger vs. older) to maximise the expected spread in measures. We conducted two serial studies using TCD- and MRI-derived measures of CVR (via inspired 5% CO2 in air). Study 1 compared 20 younger (24 ± 7 years) with 15 older (66 ± 7 years) participants, Study 2 compared 10 younger (22 ± 2 years) with 10 older (72 ± 4 years) participants. Combining the main measures across studies, no significant correlation (r = 0.15, p = 0.36) was observed between individual participant TCD- and BOLD-CVR measures. Further, these measures showed differential effects between age groups; with TCD-CVR higher in the older compared to younger group (4 ± 1 vs. 3 ± 1 %MCAv/mmHg PETCO2; p < 0.05, Hedges’ g = 0.75), whereas BOLD-CVR showed no difference (p = 0.104, Hedges’ g = 0.38). In Study 2 additional measures were obtained to understand the origin of the discrepancy: phase contrast angiography (PCA) MRI of the middle cerebral artery, showed a significantly lower blood flow (but not velocity) CVR response in older compared with younger participants (p > 0.05, Hedges’ g = 1.08). The PCA CVR metrics did not significantly correlate with the BOLD- or TCD-CVR measures. The differing CVR observations between imaging modalities were despite expected, correlated (r = 0.62–0.82), age-related differences in resting CBF measures across modalities. Taken together, findings across both studies show no clear relationship between TCD- and BOLD-CVR measures. We hypothesize that CVR differences between imaging modalities are in part due to the aspects of the vascular tree that are assessed (TCD:arteries; BOLD:venules/veins). Further work is needed to understand the between-modality CVR response differences, but caution is needed when comparing CVR metrics derived from different imaging modalities.


Author(s):  
Emmanuel Ifeanyi Obeagu ◽  
Ayomiposi Ibironke Busari ◽  
Immaculata Ogochukwu Uduchi ◽  
I. A. Ogomaka ◽  
Adaobi Maryann Ibekwe ◽  
...  

Background: Malaria is a life-threatening infectious disease of widespread burden. Malaria remains a leading communicable disease in the developing countries of the world. It occurs mostly in the tropical and subtropical regions and accounts for considerable morbidity and death. Malaria which is liable for a major amount of mortalities in endemic countries has been revealed to have both direct and indirect impacts on the haematologicalparameters.The study was done to compare the levels of haematological parameters of asymptomatic malaria patients based on age groups. Methods: The study is a cross-sectional study among asymptomatic malaria patients based on age groups. This study was conducted in Oda Road area of Akure, Ondo State. Two hundred (200) subjects were recruited for this study with each group comprising of 100 subjects for patients with asymptomatic malaria for the 2 age groups (16-30 years and 31-65 years). The data were presented in tables and as mean ± standard deviation and analyzed using student-test for parametric data and chi-square for non parametric data by statistical packages for social sciences (SPSS, Version 20.0) and level of significance set at as p≤ 0.05. Results: The results showed that subjects on age group 16-30 years were 100(50%) comprising of 50 males (25%) and 50 females (25). Also age group 31-65 years has 100 subjects (50%) comprising of 50 males (25%) and 50 females (25).The results showed significant difference in MCV (p=0.008), MCH (p=0.024) and no significant difference in PCV (p=0.675), WBC (p= 0.224), LYM (p=0.109), GRAN (p=0.061), MID (p=0.066), RBC (p=0.119), Hb (p=0.546), MCHC (p=0.262), PLT (p=0.783), when compared between age groups in years (16-30 and 31-65). Conclusion: The study showed increase in MCV and MCH of asymptomatic malaria patients within the age group of 31-65 years compared to asymptomatic malaria patients on 16-30 years age group. This shows that microcytic hypochromic anaemia may be experienced in asymptomatic malaria patients within the age group of 16-30 years more than in 31-65 years age group.


2016 ◽  
Vol 4 (1) ◽  
pp. 31-34
Author(s):  
Fatema Zohora ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Hasna Hena ◽  
Hosna Ara Perven ◽  
...  

Background: Variations in weight of the kidney in different populations and in different age groups are evident.Objective: The aim of the present study was to find out age related changes in weight of the kidney in a Bangladeshi population and compare with previous local and foreign studies.Materials and method: This cross-sectional study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, Bangladesh from July 2008 to June 2009, based on collection of 140 post mortem human kidneys collected from 70 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine of same institute. All the samples were divided into three different age groups - A (10-19 years), B (20-39 years) and C (40-59 years), and the weight of each kidney was measured by using a digital balance and recorded.Results: The weight of the right and left kidneys were found 86.18±0.32 gm and 86.10±0.10 gm in group A, 102.25±7.64 gm and 101.96±7.27 gm in group B, 95.59±0.75 gm and 95.19±1.24 gm in group C respectively. No difference was found between the right and left kidneys in any group. However, statistically significant differences were evident among age groups.Conclusion: The weight of the kidney was found to increase up to 4th decade of life and then declined with further advancing age.Delta Med Col J. Jan 2016 4(1): 31-34


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