scholarly journals Evaluation of optimum inclusion levels of biostrong® 510 15% as a replacement for antibiotic growth promoters in broiler chicken production under field conditions in Nigeria

2020 ◽  
Vol 46 (3) ◽  
pp. 82-100
Author(s):  
O. Moses ◽  
P. A Onimisi ◽  
J. O Jegede ◽  
M. Afolayan
Keyword(s):  
Liver Function ◽  
Broiler Chicken ◽  
Pathogenic Bacteria ◽  
Density Lipoprotein ◽  
Quality Parameters ◽  
Control Treatment ◽  
Control Group ◽  
Growth Promoters ◽  
Liver Health ◽  
Antibiotic Growth Promoters

An experiment was conducted to evaluate the efficacy of Biostrong® 510 15% (BSG) inbroiler chickens diet. It was included at 0 g, 75 g, 100 g and 125 g/100 Kg diet, for T1-T4respectively while T5 had Oxytetracycline. Data was collected on growth performanceindices, haematological parameters, liver function indices, kidney function, blood mineralprofile, immune response, antioxidant capacity, villi morphometrics, lipid profile, ileum andceacum microbial contents, carcass quality parameters, and tibia bone quality indices. Alldata collected were subjected to analysis of variance and significant differences amongtreatment means were compared using the Tukey test of significance. Growth  erformance showed that broilers fed diet containing 100g BSG had optimum performance among other levels. Haematological and liver function indices were not significantly (P>0.05) different. Birds fed BSG showed decreased cholesterol, triglycerides and high-density lipoprotein compared to the control treatment. Birds fed levels of BSG and AGP had significantly higher bone weight, bone density, bone dry matter and bone ash as compared to birds on the control group. All carcass evaluation parameters were significantly (P<0.05) different among treatments except for dressed weight, breast and kidney. Levels of BSG in the diet significantly lowered the cost of production than AGPs of finisher broilers improved liver health, bone strength, villi characteristics, increased beneficial bacteria population and also prevent the colonization of the gut by pathogenic bacteria thus improving the health of the birds. Biostrong® 510 15%, can therefore effectively replace antibiotic growth promoters in broiler chicken production.

scholarly journals Therapeutic Impact of Costus (Saussurea lappa) Against Ehrlich Solid Tumor-Induced Cardiac Toxicity and DNA Damage in Female Mice

2021 ◽  
Vol 12 ◽  
Author(s):  
Rehab M. Elgharabawy ◽  
Ibrahim El Tantawy El Sayed ◽  
Nada Abd-Allah Rezk ◽  
Ehab Tousson
Keyword(s):  
Breast Cancer ◽  
Dna Damage ◽  
Creatine Kinase ◽  
Solid Tumor ◽  
Cardiac Toxicity ◽  
Density Lipoprotein ◽  
Control Treatment ◽  
Control Group ◽  
Female Mice ◽  
Saussurea Lappa

Breast cancer remains the most common cause of cancer deaths among women globally. Ehrlich solid tumor (EST) is a transplantable tumor model for simulating breast cancer. This study aims to describe the protective role of costus (Saussurea lappa) root against EST-induced cardiac toxicity. Forty female mice were randomly and equally divided into four groups (G1, control group; G2, costus group; G3, EST group; G4, EST + costus). The results showed that compared to the control, EST induced a significant increase in lactate dehydrogenase, creatine kinase, creatine kinase myoglobin, aspartate aminotransferase, and alkaline phosphatase activities; in potassium, chloride ion, cholesterol, triglyceride, and low density lipoprotein levels; in DNA damage and cardiac injury; and in p53 and vascular endothelial growth factor expression. Conversely, EST induced a significant decrease in sodium ion and high density lipoprotein levels and Ki67 expression compared to the control. Treatment of EST with costus improved cardiac toxicity, lipid profiles, electrolytes, and apoptosis, and protected against EST. This indicates the potential benefits of costus as an adjuvant in the prevention and treatment of cardiac toxicity.

Phage-mediated dissemination of virulence factors in pathogenic bacteria facilitated by antibiotic growth promoters in animals: a perspective

2017 ◽  
Vol 18 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Migma Dorji Tamang ◽  
Hoon Sunwoo ◽  
Byeonghwa Jeon
Keyword(s):  
Antibiotic Resistance ◽  
Virulence Factors ◽  
Pathogenic Bacteria ◽  
Growth Promotion ◽  
Bacterial Species ◽  
Agricultural Practice ◽  
Growth Promoters ◽  
Antibiotic Resistant ◽  
The World ◽  
Antibiotic Growth Promoters

AbstractAddition of sub-therapeutic antibiotics to the feed of food-producing animals for growth promotion and disease prevention has become a common agricultural practice in many countries. The emergence of antibiotic-resistant pathogens is a looming concern associated with the use of antibiotic growth promoters (AGPs) around the world. In addition, some studies have shown that AGPs may not only affect antibiotic resistance but may also stimulate the dissemination of virulence factors via bacteriophages. Although only a few studies are currently available in the literature regarding this topic, in this article we endeavor to provide a perspective about how AGPs would impact the transmission of virulence factors by horizontal gene transfer via phages in a few pathogenic bacterial species significant to livestock production.

scholarly journals Different antibiotic growth promoters induce specific changes in the cecal microbiota membership of broiler chicken

PLoS ONE ◽  
2017 ◽  
Vol 12 (2) ◽  
pp. e0171642 ◽  
Author(s):  
Marcio C. Costa ◽  
Jose A. Bessegatto ◽  
Amauri A. Alfieri ◽  
J. Scott Weese ◽  
João A. B. Filho ◽  
...  
Keyword(s):  
Broiler Chicken ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
Cecal Microbiota

Butyric acid as a promising alternative to antibiotic growth promoters in broiler chicken production

2019 ◽  
Vol 157 (1) ◽  
pp. 55-62
Author(s):  
M. Raza ◽  
A. Biswas ◽  
N. A. Mir ◽  
A. B. Mandal
Keyword(s):  
Uric Acid ◽  
Butyric Acid ◽  
Broiler Chicken ◽  
Glucose Transporter ◽  
Body Weight Gain ◽  
Serum Biochemistry ◽  
Peptide Transporter ◽  
Growth Promoters ◽  
Promising Alternative ◽  
Antibiotic Growth Promoters

AbstractThe current work studied the effects of butyric acid (BA) supplementation on the growth performance, carcase characteristics, immunity, gut histology and serum biochemistry of broiler chicken. Four experimental diets were formulated: control, 20 mg bacitracin methylene di-salicylate/kg diet (BMD-supplemented), 3 g BA/kg diet and 4 g BA/kg diet. The results revealed higher body weight gain (BWG) in BA and BMD-supplemented groups. Only BMD supplementation increased the feed intake (FI) of birds, whereas BA supplementation improved feed efficiency. Expression of glucose transporter (GLUT5), sodium-dependent glucose transporter (SGLT1) and peptide transporter (PepT1) were up-regulated due to BMD and BA supplementation. However, at 21 days post-hatching SGLT1 expression in the BMD-supplemented group was down-regulated with respect to the BA-supplemented groups. The 4 g BA/kg diet yielded better humoral and cell-mediated immune responses than the other groups. No dietary effects were observed on carcase characteristics and histomorphometry of jejunum at 7 days post-hatching. However, at 42 days old, the 4 g BA/kg diet increased villus length and width significantly. There was a significant increase in serum protein, albumin, creatinine, aspartate aminotransaminase (AST), phosphorus and calcium due to BA supplementation. However, the reverse trend was observed in serum uric acid and cholesterol, where BA supplementation decreased both and BMD supplementation decreased uric acid levels only. Based on the results it was concluded that 4 g BA/kg diet supplementation in feed is optimal for desirable broiler production.

scholarly journals Probiotic properties of Saccharomyces cerevisiae ŁOCK 0119 yeast

2019 ◽  
Vol 120 (3) ◽  
pp. 196-209
Author(s):  
Agnieszka Chlebicz-Wójcik ◽  
Katarzyna Śliżewska ◽  
Adriana Nowak
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Yeast Strain ◽  
Pathogenic Bacteria ◽  
Live Cells ◽  
Probiotic Properties ◽  
Growth Promoters ◽  
Salmonella Spp ◽  
Probiotic Potential ◽  
Livestock Breeding ◽  
Antibiotic Growth Promoters

Probiotics including their combinations with prebiotics known as synbiotics have been extensively studied as an alternatives to antibiotic growth promoters commonly used in livestock breeding. Among many microorganisms that may be useful for their host, the Saccharomyces cerevisiae yeast exhibits probiotic potential. The objective of the research study was to select a S. cerevisiae strain suitable for use as a probiotic in newly developed synbiotic preparations for monogastric animals (poultry, swine). The survivability of yeast strains in the presence of bile salts and under low-pH conditions varied and after 4 h of incubation it ranged from 66 to 94 % and from 68 to 97 %, respectively. The S. cerevisiae ŁOCK 0119 strain was characterised by the highest survival rate; the number of live cells of this strain was reduced not more than 9 % after 4 h of incubation under the fixed conditions. Also, this strain exhibited hydrophilic properties and a strong auto- and co-aggregation potential. The selected yeast strain aggregated with pathogenic bacteria (Salmonella spp., Listeria monocytogenes) to a varying degree ranging between 40 and 75 %. The S. cerevisiae ŁOCK 0119 strain inhibited the adhesion of pathogens to the Caco-2 cells, whereby the adhesion of morbific bacteria attachment was reduced to a varying degree (15 ÷ 37 %). Based on the results obtained, it was concluded that the selected S. cerevisiae yeast strain had beneficial properties since it was able to survive during gastrointestinal passage, to colonize the intestines and to reduce the growth of pathogenic microbiota.

Quality and stability of meat obtained from broiler chickens fed diets containing tonic root (Mondia whitei) as supplement

2020 ◽  
Vol 47 (3) ◽  
pp. 99-109
Author(s):  
K. A. Sanwo ◽  
A. V. Adegoke ◽  
O. Y. Ayo – Ajasa ◽  
A. O. Fagbohun ◽  
T. M. Adeyanju
Keyword(s):  
Broiler Chickens ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Thiobarbituric Acid ◽  
Quality Parameters ◽  
Control Group ◽  
Broiler Chicks ◽  
Thiobarbituric Acid Reactive Substance ◽  
Treatment Groups ◽  
Inclusion Level

Tonic root has been speculated to improve Libido and this could have effect on performance and carcass traits of the animal. Afifty-six days experiment was conducted to determine meat quality of Abor acre Strain of broiler chickens fed graded dietary inclusion of supplemental white ginger (Mondia whitei). One hundred and eighty, one day-old broiler chicks were assigned to five treatment groups with three replicates per group. Birds on treatment one were fed concentrate with no supplements, those on treatment two had concentrate + 0.5g Mondia whitei per kg feed, treatment three had concentrate + 1g Mondia whitei per kg feed; Treatment 4 had concentrate with 1.5g Mondia whitei per kg feed and treatment five had concentrate + 2g Mondia whitei per kg feed. At the end of the eight weeks feeding trial, three birds each from each replicate of five treatment groups were randomly selected, deprived of food for 12 hours prior to slaughtering. After the traditional slaughtering method, feather plucking and evisceration were done and breast muscles were excised from the carcasses for quality parameters evaluation. The results showed significance (P< 0.05) in some measured parameters such as colour, yellowness (b*) and Lightness (L*). Highest (P<0.05) triglyceride content of meat (145.33 mg/dL) was recorded in the meat of birds fed inclusion level at 0.5g/kg and the lowest value (91.67mg/dL) in the meat of birds fed inclusion level of 1g/kg. Breast muscles had the highest (P<0.05) pH score 6.72 at 1g/kg inclusion level and least value of 6.51 was in the control group. Dietary inclusion of Mondia whitei showed no significant (P>0.05) effect on cholesterol, high density lipoprotein (HDL) and low-density lipoprotein (LDL). Although superoxide dismutase (SOD) and water absorptive power were not significantly (P>0.05) influenced, cooking and refrigeration loss as well as thiobarbituric acid reactive substance (TBARS) in meat were significantly (P<0.05) lowest in birds fed 1g/kg dietary inclusion level of Mondia whitei. Some phytochemicals and overall sensory acceptability were statistically influenced by the dietary treatments.

scholarly journals A Review on Effects of Aloe Vera as a Feed Additive in Broiler Chicken Diets

2014 ◽  
Vol 14 (3) ◽  
pp. 491-500 ◽  
Author(s):  
Darabighane Babak ◽  
Samuel N. Nahashon
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Aloe Vera ◽  
Ethanolic Extract ◽  
Feed Additive ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
Anti Fungal

AbstractProhibition of application of antibiotic growth promoters in broiler chicken diets has resulted in increased use of herbs as natural additives in broiler feeds over the recent years. Researchers particularly look for herbs that can affect such parameters as growth performance, immune response, or treatment of certain diseases. Aloe vera is a well-known herb characterized by properties such as anti-bacterial, anti-viral, anti-fungal, anti-tumor, anti-inflammatory, immunomodulatory, wound-healing, anti-oxidant, and anti-diabetic effects. During the past years, attention has shifted toward Aloe vera as a natural additive to broiler diets, and studies have shown that Aloe vera can improve immune response and growth performance in broilers. In addition, Aloe vera is an excellent alternative for antibiotic growth promoters and anticoccidial drugs. Since Aloe vera can be used for broilers in the form of gel, powder, ethanolic extract, aqueous extract, and a polysaccharide contained in Aloe vera gel (i.e. acemannan), more studies are required to determine the best form and to compare Aloe vera with other medicinal herbs. This paper reviews effects of Aloe vera on intestinal microflora, growth performance, immune response, and coccidiosis in broiler chickens.

scholarly journals The Effect of Antibiotic Growth Promoters (AGP) on Antibiotic Resistance and the Digestive System of Broiler Chicken in Sleman, Yogyakarta

2021 ◽  
Vol 33 ◽  
pp. 04005
Author(s):  
Tri Untari ◽  
Okti Herawati ◽  
Marla Anggita ◽  
Widya Asmara ◽  
Agnesia Endang Tri Hastuti Wahyuni ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Digestive Tract ◽  
Broiler Chickens ◽  
Broiler Chicken ◽  
Feed Additives ◽  
Public Understanding ◽  
Economic Losses ◽  
Growth Promoters ◽  
Antibiotic Growth Promoters ◽  
The Impact

Chicken is a major source of animal protein consumption in Indonesia. The problem facing the poultry industry is the incidence of resistance which increases mortality of the chicken production. One of the causes of resistance case is the use of antibiotics in feed additives. The public understanding about the effects of the use of antibiotic growth promoters (AGP) in chickens in antibiotic resistance and the digestive tract of chicken needs to be done to avoid the impact on economic losses and health problems. This study aims to provide an understanding of the effects of the use of antibiotic growth promoters (AGP) on antibiotic resistance and the digestive tract of broiler chickens. This study was carried out at a broiler chicken farm in Sleman, Yogyakarta. Based on the histopathological result of the digestive tract of chickens that were given antibiotics as AGP, there was no inflammation occurs, but the administration of antibiotics caused antibiotic resistance in various type of antibiotics including tetracycline (90% resistance), streptomycin (60% resistance), amoxicillin (50% resistance), erythromycin (80% resistance), and no resistance for gentamycin.

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