scholarly journals Relationship between different livestock managements and stress response in dairy ewes

2018 ◽  
Vol 61 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Vincenzo Carcangiu ◽  
Francesca Arfuso ◽  
Sebastiano Luridiana ◽  
Claudia Giannetto ◽  
Maria Rizzo ◽  
...  

Abstract. The gradual diffusion of intensive and semi-intensive production systems, especially in dairy sheep breeds, has led to the growing concern of consumers about the life conditions of farmed animals. Space allowance and structures of sheep houses are described as the main potential sources of discomfort for housed flocks, together with inappropriate milking procedures and human–animal interactions. The aim of the present study was to evaluate whether the structure relative to milking room could represent a stressor in Sarda dairy ewes. Animals were divided into two groups according to their farm of origin. Group A (n=40) was from a farm whose milking room was an old warehouse with a waiting area limited and located outdoors and at a different level with respect to the milking room. The passageway of the entrance in the milking room was narrow and perpendicular to the milking positioning so the animal must bend 90∘ to enter in the room. Group B (n=40) was from a farm whose milking room was wide and modern with a large waiting area located at the same level. From all animals blood samples were collected at T0 (2 h before milking procedure at 06:00), at T1 (immediately after the animals entered the milking room, about 08:00) and at T2 (after milking procedure). In addition plasma cortisol and glucose values were evaluated. Statistical analysis showed significant effect of milking room (P<0.001) and of sampling time (P<0.05) on cortisol and glucose levels. The results obtained in the present study suggest that, in addition to milking, the characteristics of the room where this procedure occurs represent stressful stimuli that could influence negatively the productivity and welfare of dairy ewes.

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Jeffrey Nadelson ◽  
Sanjaya K. Satapathy ◽  
Satheesh Nair

Introduction. Aim of this study is to determine if HbA1c levels are a reliable predictor of glycemic control in patients with decompensated cirrhosis.Methods. 200 unique patients referred for liver transplantation at University of Tennessee/Methodist University Transplant Institute with a HbA1c result were included. Three glucose levels prior to the “measured” A1c (MA1c) were input into an HbA1c calculator from the American Diabetes Association website to determine the “calculated” A1c (CA1c). The differences between MA1c and CA1c levels were computed. Patients were divided into three groups: group A, difference of <0.5; group B, 0.51–1.5; and group C, >1.5.Results. 97 (49%) patients had hemoglobin A1c of less than 5%. Discordance between calculated and measured HbA1c of >0.5% was seen in 47% (n=94). Higher level of discordance of greater than >1.5 was in 12% of patients (n=24). Hemoglobin was an independent predictor for higher discordance (odds ratio 0.77 95%, CI 0.60–0.99, andpvalue 0.04). HbA1c was an independent predictor of occurrence of HCC (OR 2.69 955, CI 1.38–5.43, andpvalue 0.008).Conclusion. HbA1c is not a reliable predictor of glycemic control in patients with decompensated cirrhosis, especially in those with severe anemia.


1993 ◽  
Vol 13 (2_suppl) ◽  
pp. 242-244 ◽  
Author(s):  
Sophia Spaia ◽  
Fotini Christidou ◽  
Panayotis Pangidis ◽  
Thomas Tsoulkas ◽  
Michalis Pazarloglou ◽  
...  

In order to evaluate the Influence of diabetes mellitus on peritoneal membrane permeability, we studied the peritoneal protein loss In two groups of patients. Group A consisted of 16 patients (9 nondlabetics and 7 diabetics) who were In the first month of treatment on continuous ambulatory peritoneal dialysis (CAPO). Group B consisted of 13 patients (7 nondlabetics and 6 diabetics) who had been on CAPO for approximately 15 months. In both groups we measured the body weight, serum total protein, albumin, and total protein, urea, and glucose In the peritoneal fluid. We did not find any difference In groups A and B between diabetics and nondlabetics as far as the estimated parameters were concerned. Age, body weight, serum biochemistry, and protein and urea content In peritoneal fluid were similar, when group A was compared to group B. Patients of group B hed on average higher protein losses than those who had been on the method for a short period (mean 7.9 g/dL, vs 6.09 g/dL). Six patients were followed for over 15 months and were found to have significantly Increased protein losses (p=0.02). Glucose levels In peritoneal fluid were significantly lower In patients In group B, p<0.05 (mean 51.8 g/dL vs 37.1 g/dL). Peritoneal protein loss does not seem to differ between diabetic and nondiabetic patients with end-stage renal disease treated with CAPO, at any given time of the treatment. We observed an Increase In protein loss In some patients and a tendency to Increase the protein loss In others. This, along with the fall In glucose levels, might reflect progressive alterations In structure and permeability of the elements Involved In peritoneal transport, and It should receive further evaluation.


1991 ◽  
Vol 125 (5) ◽  
pp. 510-517 ◽  
Author(s):  
Andrea Giustina ◽  
Simonetta Bossoni ◽  
Corrado Bodini ◽  
Antonino Cimino ◽  
Giuseppe Pizzocolo ◽  
...  

Abstract. We evaluated the effects of iv pretreatment with exogenous GH on the GH response to GHRH either alone or in combination with pyridostigmine in 14 Type I diabetic patients and 6 normal subjects. All the subjects received an iv bolus injection of biosynthetic human GH, 2 IU; 2 h later they received either a. pyridostigmine, 120 mg orally, or b. placebo, 2 tablets orally, followed 1 h later by iv injection of GHRH(1-29) NH2, 100 μg. In normal subjects the median GH peak after GH+GHRH was 1.8, range 1.2-6.9 μg/l. Pyridostigmine enhanced the GH response to GHRH in all subjects. The median GH peak after pyridostigmine+ GH+GHRH was 32.7, range 19.8-42.1 μg/l (p<0.001 vs GHRH alone). Seven diabetic subjects had median GH peaks after GH+GHRH >6.9 μg/l (the maximum GH peak after GH+GHRH in normal subjects) (group A: median GH peak 35.7, range 21.7-55 μg/l). The other diabetic subjects had GH peak lower than 6.9 μg/l (group B: median GH peak 4.4, range 2.1-6.5 μg/l). Pyridostigmine significantly increased the GH response to GHRH in group B patients (median GH peak 29.3, range 15.7-93.4 μg/l, p<0.001 vs GH+GHRH alone), but not in group A patients (median GH peak 39.9, range 21.9-64.9 μg/l). Group A diabetic patients were younger and had higher HbA1c and blood glucose levels than group B patients. In those diabetic patients with an exaggerated GH response to GH+GHRH, pyridostigmine failed to cause the increase in GH secretion observed in diabetic and control subjects with no responses to GH+GHRH. It can be suggested that elevated 24-h GH levels in some Type I diabetic patients may be due to decreased somatostatinergic tone which in turn causes altered autoregulation of GH secretion. We hypothesize that this finding is a consequence of a reset of the hypothalamic control of GH secretion caused by a chronically elevated blood glucose level in this subpopulation.


2021 ◽  
Vol 7 (5) ◽  
pp. 2938-2945
Author(s):  
Xinxia Zhang ◽  
Kunpeng Xu ◽  
Na Zhang

The purpose of this study was to investigate the relationship between islet cell antibodies and cell function in children with diabetes mellitus. Objective: To investigate the effects of insulin resistance and B-cell failure on blood glucose levels in children with diabetes, so as to provide theoretical basis for rational choice of hypoglycemic drugs and effective control of blood glucose. Methods: 81 children with diabetes mellitus were tested after eating 80g instant noodles for 0, 30, 60,120 min of blood glucose and insulin. All cases were divided into group A (FPG < 8.92mmol /L) and group B (FPG≥ 8.89mmol /L) according to the fasting blood glucose (FFG) level. The contribution of cell function and insulin resistance to the blood glucose level was assessed in both groups. Results: The sensitivity of insulin and true insulin in group B was 65.5% and 64% of that in group A. After adjusting the effect of insulin resistance, the cell function in group B was only 1/5-1/7 of that in group A. Insulin swabs and cell function, measured by insulin, contributed half to glucose levels in group A, while cell function contributed eight times as much to glucose levels as insulin resistance in group B. Beta cell secretory function, measured with true insulin, explained 43% of the change in blood glucose in group A, 55% of the change in blood glucose in group B, and insulin sensitivity explained 13% of the change in group A, and 5.9% of the change in group B. Conclusion: Insulin resistance and cell failure were more serious in the group with higher fasting glucose level (≥ 8.89mmol /L), and the hyperglycemia was mainly caused by cell failure, suggesting that the combination of insulin sensitizer and insulin secretory agent was beneficial in the initial treatment.


Author(s):  
Shagufta Parveen ◽  
Asim Ali Khan ◽  
Qamar Alam Khan

Intermediate hyperglycemia (Prediabetes) is a type of metabolic disorder with slight increase in the blood glucose levels from the normal but not reaching up to the level of diabetes. It is associated with many micro-vascular as well as macro-vascular complications. Abundance of Unani medicines are known for anti-hyperlipidemic activity, among them is Maghz-e-Jamun (Eugenia jambolana). The present study was to evaluate the anti-hyperlipidemic effect of Maghz-e-Jamun (Eugenia jambolana) in intermediate hyperglycemia. Patients diagnosed with prediabetes as per ADA criteria were randomly divided in two groups- group A was supplemented with 4.5g powder /day jamun seed powder in the form of capsules and group B was given placebo capsules. Lipid profile assessment was done at baseline and end of the treatment i.e., 84th day. There is considerable improvement in the lipid profile of the prediabetic subjects enrolled in the study especially significant improvement in total cholesterol level (from 266.47 ± 62.92 to 216.058 ± 40.14 with p value of 0.008**) and LDL (from 189.23 ± 55.07 to 138.58 ± 34.86 with p value of 0.003**). -Maghz-e-Jamun (Eugenia jambolana) show substantial effect on dyslipidemia in the patients of intermediate hyperglycemia.


Author(s):  
Krishna Kumar

The aim of the present study was to observe the effect of intravenous Dexmedetomidine on levels of blood glucose, which is one among several stress response markers under General Anesthesia (GA) for laparoscopic intra-peritoneal surgeries. The study was planned in the Department of Anaesthesia in Sri  Krishna  Medical  College  and  Hospital,  Muzaffarpur, from Jan 2016 to Oct 2016.The 30 patients undergoing for laparoscopic intra-peritoneal surgeries of 1-2 hours duration with minimal expected blood loss were enrolled.  The approval of the institutional committee was taken prior conduct of study. All the patients were informed consents. The 15 patients in Group A received loading dose of Inj. Dexmedetomidine 1µg/kg/10min diluted to 50ml with Normal Saline, given before induction, followed by maintenance dose 0.5µ/kg/hour till the end of surgery. The 15 patients in Group B received Normal Saline in a similar manner. Dexmedetomidine, a highly selective α2-adrenergic receptor agonist has generated lot of interest for its sedative, analgesic, perioperative sympatholytic, anesthetic-sparing, and hemodynamic-stabilizing properties. The data generated in the two study groups in the present study concludes that the use of dexmedetomidine maintains blood glucose levels and favourably influencing the intra operative stress induced blood glucose levels. Keywords:  Dexmedetomidine, Stress induced blood glucose levels, laparoscopic intra-peritoneal surgeries, etc.


2021 ◽  
Vol 11 (5-S) ◽  
pp. 19-24
Author(s):  
Samuel I. Ogenyi ◽  
Ezinne Imoko ◽  
Anthony A. Ngokere ◽  
Amalachukwu O. Ike

Introduction: The study aims to evaluate the anti-hyperglycaemic effect of turmeric and the histological changes in the pancreas of adult Wistar rats. Materials and Methods: Forty adult Wistar rats were divided into four groups of [A-D] ten rats per group. Group A was normal control, group B was diabetic control, group C was treated with 300mg/kg weight of extract and group D was 500mg/kg body weight. All animals had access to food and water ad libitum.  Aqueous extract of turmeric was administered orally, once daily for 14 days. The rats were then anaesthetized with dichloromethane before sacrifice and sample collection. Pancreatic tissues were processed, stained using the hematoxylin and eosin (H&E) method. Blood glucose estimation was determined using the glucose oxidase method. Results: The mean body weights of the rats across groups were not statistically significant. Similarly, blood glucose levels across groups revealed a progressive statistically significant increase from group A to D and from day one to day 17. Pairwise comparison of group A with B, C and D showed a statistically significant increase but a comparison of Group B with C and D were not significant. Discussion: There was progressive body weight increase of the rats from day one to the final day across all groups and reduction in the blood glucose levels of the animals treated with 300mg/kg and 500mg/kg body weights, after seven days of treatment, but these, progressively increased with time even with treatment. The overall pancreas features indicate moderate inflammatory changes. Keywords: turmeric, anti- hyperglycemia, alloxan, Wistar rats


Author(s):  
Luis Alcides Brandini De Boni ◽  

Background: In late 2019, a new coronavirus variant, SARS-CoV-2, emerged and caused a pandemic. Several were the consequences of the appearance of this new virus, including, but not limited to, death, unemployment, bankruptcies (moral and economic), hunger, and misery. Aim: the purpose of this work is to analyze two hypotheses through logical propositions about the possibility of natural origin, or not, of SARS-CoV-2. Methods: research in an open public audiovisual database, censored, and non-peer-reviewed was used to identify subjects that support the proposition that the virus has a natural origin (group A) and those who claim otherwise (group B) aiming to hear your conjecture. A photographic survey was also carried out in order to identify the characters studied. The logical analysis of the propositions was performed through the construction of an exclusive disjunction truth table. Results and Discussion: The truth table produced four scenarios, two impossible and two possible. The impossible scenarios were discarded, and the possible scenarios were analyzed and confronted with the results of the audiovisual research. Conclusions: with the exclusion of impossible scenarios, only the possibilities remain that SARS-CoV-2 has evolved or not naturally, one of the lines of reasoning will be wrong as to the origin of SARS-CoV-2 if it ever becomes determined.


Jurnal NERS ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. 246
Author(s):  
Nursalam Nursalam ◽  
Rista Fauziningtyas ◽  
Candra Panji Asmoro ◽  
Kusnanto Kusnanto ◽  
Merryana Adriani

ABSTRAK :Pendahuluan: Kesadaran masyarakat terhadap gaya hidup sehat menyebabkan perubahan pada pemilihan bahan makanan untuk dikonsumsi. Penambahan tepung Pisang dan Sukun meningkatkan kadar serat pada mie. Tujuan penelitian ini adalah untuk menentukan komposisi tepung pengganti pada mie yang berefek pada peningkatan GDS paling rendah. Metode: Desain penelitian ini adalah control group pretest posttest design.  Sample didapatkan sebanyak 58 orang mahasiswa Fakultas Keperawatan Unair yang memenuhi kriteria inklusi dan eksklusi. 58 sampel dibagi menjadi 3 kelompok, yaitu mi A (kontrol), B (subtitusi 30%) dan C (subtitusi 20%). Pemeriksaan GDS dilakukan sebelum pemberian Mi dan 60 menit setelah pemberian mi. Analisa data yang digunakan adalah dengan ANOVA one way. Hasil: Berdasarkan uji ANOVA one way didapatkan p=0,000 (p<0,050) yang berarti ada perbedaan hasil pada ke tiga kelompok tersebut. Kenaikan tertinggi Nilai GDS adalah pada kelompok mi A dan terendah kelompok mi B.Diskusi: Penambahan tepung pisang dan sukun pada mie dapat menurunkan kenaikan nilai GDS responden bukan penderita DM. Penelitian lebih lanjut perlu dilakukan untuk mengetahui kandungan mi dengan tepung pisang dan sukun dan respon GDS pada penderita DM. Kata Kunci: Mi, Tepung, Pisang, Sukun, Gula Darah, Diabetes ABSTRACT :Introduction: Public awareness of healthy lifestyles cause a change in the selection of foodstuffs for consumption. Bananas and breadfruit flour additions increase the fiber content on the noodles. The purpose of this study was to determine the composition of noodles flour substitute on the effect on an increase in the lowest Glucose levels. Methods: The research design was pretest posttest control group design. Sample obtained as many as 58 students of the Faculty of Nursing University of Airlangga who meet the inclusion and exclusion criteria. 58 samples were divided into three groups, namely Noodles A (control), B (substitution 30%) and C (substitution 20%). Glucose levels examination carried out before eating noodles and 60 minutes after eat it. The data analysis of this study was the one-way ANOVA. Results: Based on the one-way ANOVA test was obtained p = 0.000 (p <0.050), which means no differences in outcomes in all three groups. The highest increasing of glucose levels is group A and the lowest in group B. Discussion: The addition of banana and breadfruit flour on the noodles can reduce the increase in the glucose levels after eat it. Further research needs to be done to determine the content of noodles with a banana and breadfruit flour and glucose’s responses in patients with diabetic mellitus. Keywords : Noodles, Flour, Banana, Breadfruit,Glucose, Diabetic Mellitus.


Nutrients ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 3522
Author(s):  
Spyridon Karras ◽  
Cedric Annweiler ◽  
Dimitris Kiortsis ◽  
Ioannis Koutelidakis ◽  
Kalliopi Kotsa

We have previously described increased fasting plasma glucose levels in patients with normocalcemic primary hyperparathyroidism (NPHPT) and co-existing prediabetes, compared to prediabetes per se. This study evaluated the effect of parathyroidectomy (PTx) (Group A), versus conservative follow-up (Group B), in a small cohort of patients with co-existing NPHPT and prediabetes. Sixteen patients were categorized in each group. Glycemic parameters (levels of fasting glucose (fGlu), glycosylated hemoglobin (HbA1c), and fasting insulin (fIns)), the homeostasis model assessment for estimating insulin secretion (HOMA-B) and resistance (HOMA-IR), and a 75-g oral glucose tolerance test were evaluated at baseline and after 32 weeks for both groups. Measurements at baseline were not significantly different between Groups A and B, respectively: fGlu (119.4 ± 2.8 vs. 118.2 ± 1.8 mg/dL, p = 0.451), HbA1c (5.84 ± 0.3 %vs. 5.86 ± 0.4%, p = 0.411), HOMA-IR (3.1 ± 1.2 vs. 2.9 ± 0.2, p = 0.213), HOMA-B (112.9 ± 31.8 vs. 116.9 ± 21.0%, p = 0.312), fIns (11.0 ± 2.3 vs. 12.8 ± 1.4 μIU/mL, p = 0.731), and 2-h post-load glucose concentrations (163.2 ± 3.2 vs. 167.2 ± 3.2 mg/dL, p = 0.371). fGlu levels demonstrated a positive correlation with PTH concentrations for both groups (Group A, rho = 0.374, p = 0.005, and Group B, rho = 0.359, p = 0.008). At the end of follow-up, Group A demonstrated significant improvements after PTx compared to the baseline: fGlu ((119.4 ± 2.8 vs. 111.2 ± 1.9 mg/dL, p = 0.021) (−8.2 ± 0.6 mg/dL)), and 2-h post-load glucose concentrations ((163.2 ± 3.2 vs. 144.4 ± 3.2 mg/dL, p = 0.041), (−18.8 ± 0.3 mg/dL)). For Group B, results demonstrated non-significant differences: fGlu ((118.2 ± 1.8 vs. 117.6 ± 2.3 mg/dL, p = 0.031), (−0.6 ± 0.2 mg/dL)), and 2-h post-load glucose concentrations ((167.2 ± 2.7 vs. 176.2 ± 3.2 mg/dL, p = 0.781), (+9.0 ± 0.8 mg/dL)). We conclude that PTx for individuals with NPHPT and prediabetes may improve their glucose homeostasis when compared with conservative follow-up, after 8 months of follow-up.


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