scholarly journals Study for Whitening Effect, Antioxidant and Anti-wrinkle Activity of Tapioca-unhulled Barley Dried Distiller's Grains with Solubles

2021 ◽  
Vol 27 (6) ◽  
pp. 1447-1452
Author(s):  
Hye-Jin Park ◽  
Eun-Jeong Jeong
Keyword(s):  
Inhibitory Activity ◽  
Physiological Activity ◽  
Radical Scavenging ◽  
Hot Water ◽  
Raw Material ◽  
Control Group ◽  
Distiller's Grains ◽  
Material Supply ◽  
Radical Scavenging Ability ◽  
Whitening Activity

This study intends to present the value of use as an eco-friendly, bioactive functional material by utilizing the undervalued tapiocaunhulled barley dried distiller's grains with solubles (TBDDGS). The physiological activity of TBDDGS presented through whitening activity, antioxidant activity, and anti-wrinkle effect. As a result of measuring the mushroom tyrosinase inhibitory activity in the hot water extracts of TBDDGS, the extracts showed 1.21% at 20 mg/mL concentration, 7.39% at 50 mg/mL concentration, and 25.78% at 100 mg/mL concentration, depending on the concentration of the extracts. The radical scavenging ability of DPPH was 28.7% at 10 mg/mL concentration, 38.0% at 20 mg/mL concentration, 60.9% at 50 mg/mL concentration, and 80.1% at 100 mg/mL concentration. The collagenase inhibitory activity of the extracts was 92.8% at a 6 mg/mL concentration. Elastase inhibitory activity was 97.8% at 100 mg/mL concentration. From the above results, the collagenase inhibitory activity of the extracts was 92.8% at a 6 mg/mL concentration. The elastase inhibitory activity was 97.8% at 100 mg/mL concentration. Although TBDDGS in this study has lower physiological activity compared to the control group, it was considered to have industrial value as a functional cosmetic raw material in consideration of the advantages of stable raw material supply and price competitiveness as an eco-friendly cosmetic raw material.

scholarly journals Preparation of Antioxidant and Antibacterial Chitosan Film from Periplaneta americana

Insects ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 53
Author(s):  
Sicong Chen ◽  
Xunfan Wei ◽  
Zhuoxiao Sui ◽  
Mengyuan Guo ◽  
Jin Geng ◽  
...  
Keyword(s):  
Food Packaging ◽  
Periplaneta Americana ◽  
Uv Light ◽  
Radical Scavenging ◽  
Chitosan Film ◽  
American Cockroach ◽  
Raw Material ◽  
Potential Resource ◽  
Radical Scavenging Ability ◽  
Dpph Radical Scavenging

Among different insects, the American cockroach (Periplaneta americana) has been bred in industrial scale successfully as a potential resource of protein, lipid, and antibacterial peptide. However, the application of its chitosan has not been studied widely, which has hindered the sufficient utilization of P. americana. In this paper, the chitosan from P. americana was separated, characterized, and processed into film (PaCSF) to examine its potential of being applied in food packaging. As the results of different characterizations showed, PaCSF was similar to shrimp chitosan film (SCSF). However, concerning the performances relating to food packaging, the two chitosan films were different. PaCSF contained more water (42.82%) than SCSF did, resulting in its larger thickness (0.08 mm). PaCSF could resist UV light more effectively than SCSF did. Concerning antioxidant activity, the DPPH radical scavenging ability of PaCSF increased linearly with time passing, reaching 72.46% after 8 h, which was better than that of SCSF. The antibacterial activity assay exhibited that PaCSF resisted the growth of Serratia marcescens and Escherichia coli more effectively than SCSF did. The results implied that P. americana chitosan could be a potential raw material for food packaging, providing a new way to develop P. americana.

scholarly journals Comparison of Biological Activities of Different Parts of Asparagus

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 771-771
Author(s):  
Jiseon Park ◽  
Jaegeel Lim
Keyword(s):  
Inhibitory Activity ◽  
Biological Activities ◽  
Radical Scavenging ◽  
Control Group ◽  
Total Phenol Content ◽  
No Production ◽  
Dpph Radical ◽  
Scavenging Effect ◽  
Radical Scavenging Effect ◽  
Different Parts

Abstract Objectives Asparagus is a spring vegetable, a flowering perennial plant species belonging to the lily family. Technavio's analysts forecast the Global Asparagus Market to grow at a CAGR of 3.15% during the period 2018–2022. All parts of asparagus, including roots, are rich in bioactive chemicals. However, other parts except asparagus spears are discarded. This study compared the physiological activity of different parts of asparagus and tried to improve the utilization of other parts. Methods Asparagus was divided into root, spear (5 cm from the bottom, 25 cm from the top, respectively), leaf and stem in order and used after lyophilized. Total phenol content, antioxidant activity (DPPH radical elimination ability, ABTS radical elimination ability), α-amylase inhibitory activity, and the effects of nitric oxide (NO) production were measured. Results The total polyphenol content of asparagus was highest in the leaves (22.87 mg TAE/g) and lowest in 5 cm under part of the spear(3.03 mg TAE/g). DPPH radical scavenging effect (44.52% in 1 mg/mL, 92.84% in 5 mg/mL), and ABTS radical scavenging effect(15.58% in 1 mg/mL, 48.02% in 5 mg/1 mL) were the highest on the leaf. On 5 cm under part of the spear, α-amylase inhibitory activity (79.16%) was the higher than any other parts. NO generation was significantly hindered by LPS treatment group 5 cm under part of the spear (12.93 μM), 25 cm above the part of the spear (12.10 μM), root (11.68 μM), leaf(10.43 μM), and stem(9.70 μM) in order(P < 0.001). All the extracts were treated with the cells at concentrations of 100, 500 and 1000 µg/mL for one day. As a result, the survival rate of the macrophages was not significantly different from that of the control group. So it was confirmed that there is no cytotoxicity. Conclusions Thus, these results suggest that the another parts of asparagus may be highly valuable as a high-quality functional component as well as its-antioxidant, antiinflammatory activities. we believe that the results obtained would be helpful in the development of nutraceutics. Funding Sources This study was supported by 2019 Regional Specialized Technology Development Project, Rural Development Administration, Republic of Korea.

scholarly journals Extraction Optimization, Structural Characterization, and Antioxidant Activities of Polysaccharides from Cassia Seed (Cassia obtusifolia)

Molecules ◽  
2019 ◽  
Vol 24 (15) ◽  
pp. 2817 ◽  
Author(s):  
Ding-Tao Wu ◽  
Wen Liu ◽  
Qiao-Hong Han ◽  
Ping Wang ◽  
Xian-Rong Xiang ◽  
...  
Keyword(s):  
Functional Food ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Weight Ratio ◽  
Reducing Power ◽  
Natural Antioxidants ◽  
Hot Water ◽  
Raw Material ◽  
Food Ingredients ◽  
Chemical Structures

In order to explore Cassia seed polysaccharides (CSPs) as natural antioxidants for application in the functional-food industry, microwave-assisted extraction (MAE) was optimized for the extraction of CSPs by using a response surface methodology. Furthermore, the chemical structures and antioxidant activities of CSPs extracted by MAE and hot water extraction were investigated and compared. The maximum extraction yield of CSPs extracted by MAE (8.02 ± 0.19%) was obtained at the optimized extraction parameters as follows: microwave power (415 W), extraction time (7.0 min), and ratio of water to raw material (51 mL/g). Additionally, the contents of the uronic acids, molecular weight, ratio of constituent monosaccharides, intrinsic viscosities, and degrees of esterification of CSPs were significantly affected by the MAE method. Moreover, CSPs exhibited remarkable 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) ABTS, 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl DPPH, nitric oxide, and hydroxyl radical scavenging activities as well as reducing power. The high antioxidant activities observed in CSPs extracted by MAE could be partially attributed to its low molecular weights and high content of unmethylated galacturonic acid. Results indicate that the MAE method could be an efficient technique for the extraction of CSPs with high antioxidant activity, and CSPs could be further explored as functional food ingredients.

Hepatoprotective and Anti-oxidant Activities ofGlossogyne tenuifoliaAgainst Acetaminophen-Induced Hepatotoxicity in Mice

2014 ◽  
Vol 42 (06) ◽  
pp. 1385-1398 ◽  
Author(s):  
Yu-Hsiu Tien ◽  
Bing-Huei Chen ◽  
Guoo-Shyng Wang Hsu ◽  
Wan-Teng Lin ◽  
Jui-Hua Huang ◽  
...  
Keyword(s):  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Serum Levels ◽  
Oxidative Capacity ◽  
Positive Control ◽  
Hot Water ◽  
Total Phenolic ◽  
Control Group ◽  
Anti Oxidant

The present study investigated the anti-oxidative and hepatoprotective effects of Glossogyne tenuifolia (GT) Cassini, against acetaminophen-induced acute liver injury in BALB/c mice. The extracts of GT by various solvents (hot water, 50% ethanol and 95% ethanol) were compared for their 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, reducing power, total phenolic content, and total anti-oxidant capacity. The results showed that hot water (HW) extracts of GT contained high levels of phenolics and exerted an excellent anti-oxidative capacity; thus, these were used in the animal experiment. The male BALB/c mice were randomly divided into control group, acetaminophen (APAP) group, positive control group and two GT groups at low (GT-L) and high (GT-H) dosages. The results showed that mice treated with GT had significantly decreased serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). GT-H increased glutathione levels and the ratios of reduced glutathione and oxidized glutathione (GSH/GSSG) in the liver, and inhibited serum and lipid peroxidation. This experiment was the first to determine phenolic compounds, chlorogenic acid and luteolin-7-glucoside in HW extract of GT. In conclusion, HW extract of GT may have potential anti-oxidant capacity and show hepatoprotective capacities in APAP-induced liver damaged mice.

scholarly journals Skin Improvement Effects of Gardeniae fructus Extract in HaCaT Keratinocytes, B16F10 Melanocytes, and CCD-986sk Fibroblast Cells

Cosmetics ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 48 ◽  
Author(s):  
Se Hyang Hong ◽  
Jin Mo Ku ◽  
Seung Hwan Lee ◽  
Ho Jong Shim ◽  
Dong Sun Park ◽  
...  
Keyword(s):  
Free Radical ◽  
Inhibitory Activity ◽  
Radical Scavenging ◽  
Fibroblast Cells ◽  
Mrna Levels ◽  
Protein Levels ◽  
Free Radical Scavenging Assay ◽  
Free Radical Activity ◽  
Dose Dependent ◽  
Whitening Activity

The development of functional cosmetics with skin improvement effects from natural sources is necessary. In this study, the antioxidant, antiwrinkling, moisturizing, and whitening effects of Gardeniae fructus extract (GF) were investigated in keratinocytes, melanocytes, and fibroblast cells. Antioxidant activity was determined by a DPPH free radical scavenging assay. MMP-1, MMP-9, HAS1, and filaggrin mRNA levels were measured by RT-PCR in keratinocytes and fibroblast cells. MITF and tyrosinase protein levels were evaluated by blotting analysis in melanocytes. DPPH free radical activity was investigated to determine whether GF showed dose-dependent inhibitory activity. GF induced the upregulation of HAS1 and filaggrin mRNA expression in keratinocytes and fibroblast cells. GF led to the downregulation of MMP mRNA levels in keratinocytes and fibroblast cells. Western blotting was performed to confirm the whitening-related protein (MITF and tyrosinase) levels induced by GF in melanocytes, and the inhibitory activity was superior to that of the α-MSH used for the comparison test. GF showed marked antioxidant, antiwrinkling, skin moisturizing, and whitening activity in keratinocytes, melanocytes, and fibroblast cells. Through the results of these experiments, the applicability of GF as a natural and functional cosmetic material was verified.

scholarly journals Exploring the 2’-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Molecules ◽  
2021 ◽  
Vol 26 (9) ◽  
pp. 2777
Author(s):  
Ioanna Kostopoulou ◽  
Andromachi Tzani ◽  
Nestor-Ioannis Polyzos ◽  
Maria-Anna Karadendrou ◽  
Eftichia Kritsi ◽  
...  
Keyword(s):  
Aromatic Ring ◽  
Inhibitory Activity ◽  
Radical Scavenging ◽  
Structural Features ◽  
Design Synthesis ◽  
Binding Characteristics ◽  
Methoxy Groups ◽  
Direct Binding ◽  
Radical Scavenging Ability ◽  
Inhibitory Agents

2’-hydroxy-chalcones are naturally occurring compounds with a wide array of bioactivity. In an effort to delineate the structural features that favor antioxidant and lipoxygenase (LOX) inhibitory activity, the design, synthesis, and bioactivity profile of a series of 2’-hydroxy-chalcones bearing diverse substituents on rings A and B, are presented. Among all the synthesized derivatives, chalcone 4b, bearing two hydroxyl substituents on ring B, was found to possess the best combined activity (82.4% DPPH radical scavenging ability, 82.3% inhibition of lipid peroxidation, and satisfactory LOX inhibition value (IC50 = 70 μM). Chalcone 3c, possessing a methoxymethylene substituent on ring A, and three methoxy groups on ring B, exhibited the most promising LOX inhibitory activity (IC50 = 45 μM). A combination of in silico techniques were utilized in an effort to explore the crucial binding characteristics of the most active compound 3c and its analogue 3b, to LOX. Α common H-bond interaction pattern, orienting the hydroxyl and carbonyl groups of the aromatic ring A towards Asp768 and Asn128, respectively, was observed. Regarding the analogue 3c, the bulky (-OMOM) group does not seem to participate in a direct binding, but it induces an orientation capable to form H-bonds between the methoxy groups of the aromatic ring B with Trp130 and Gly247.

scholarly journals Alleviation of Kainic Acid-Induced Brain Barrier Dysfunction by 4-O-Methylhonokiol inIn VitroandIn VivoModels

2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Jin-Yi Han ◽  
Sun-Young Ahn ◽  
Jae Hyeon Yoo ◽  
Sang-Yoon Nam ◽  
Jin Tae Hong ◽  
...  
Keyword(s):  
Water Content ◽  
Kainic Acid ◽  
Physiological Activity ◽  
Radical Scavenging ◽  
Pathological Examination ◽  
Control Group ◽  
Blue Dye ◽  
Barrier Dysfunction ◽  
The Brain ◽  
Brain Tissues

This experiment was designed to investigate whether 4-O-methylhonokiol (MH), a principal ingredient ofMagnolia (M.) officinalisbark, alleviated acute intraperitoneal (i.p.) kainic acid- (KA-) induced brain blood barrier dysfunction (BBBD)viapathological examination and cytological analyses of the brain tissues of mice. KA (10–30 mg/kg) time- and dose-dependently increased the water content of brain tissues and induced edema and encephalopathy. However, pretreatment with MH (5 and 20 mg/kg, i.p.) significantly reduced the water content of the brain compared to that observed in the KA control group. Furthermore, MH significantly and dose-dependently reversed the remarkable variations in evan’s blue dye (EBD) staining and malondialdehyde (MDA) levels that were induced by KA (10 mg/kg, i.p.). MH also decreased the elevated seizure scores that were induced by KA (10 mg/kg, i.p.) in mice in a manner similar to scavengers such as DMTU and trolox. Additionally, MH significantly scavenged intracellular ROS and Ca2+within hippocampal cells. The tight junction seals mediated by claudin (Cld-5) were also found to be modulated by MH. MH efficiently reduced 1,1-diphenyl-2-picrylhydrazyl (DPPH) (IC50, 52.4 mM) and•OH with an electron spin resonance (ESR) signal rate constant of4×109 M-1·S-1, which is close to the reactivity of the vitamin E analog trolox. Taken together, these results suggest that MH may enhance radical scavenging in lipid and hydrophobic environments, which may be important for the physiological activity of the barrier.

scholarly journals Inulin as an effectiveness and safe ingredient in cosmetics

2019 ◽  
Vol 21 (1) ◽  
pp. 44-49
Author(s):  
Zofia Nizioł-Łukaszewska ◽  
Tomasz Bujak ◽  
Tomasz Wasilewski ◽  
Edyta Szmuc
Keyword(s):  
Raw Materials ◽  
Skin Irritation ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Jerusalem Artichoke ◽  
Ethanolic Extract ◽  
Biological Properties ◽  
Raw Material ◽  
Aqueous Ethanolic Extract ◽  
Radical Scavenging Ability

Abstract Jerusalem artichoke (Helianthus tuberosus) and chicory (Cichorium intybus) are valuable pharmaceutical raw materials on account of their high content of inulin, a natural prebiotic. Inulin-rich plants are also increasingly employed in the formulation of cosmetic products. The paper presents the biological properties of aqueous and aqueous-ethanolic extracts of Jerusalem artichoke and chicory. The extracts have been found to have a high free radical scavenging ability, with the most beneficial antioxidant properties being observed for the aqueous-ethanolic extract of Jerusalem artichoke. Inulin isolated from both plant types is a safe and non-toxic raw material. Inulin added to model body wash gel formulations markedly reduces their potential to cause skin irritation and sensitization.

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