ANTIMICROBIAL THERAPY FOR DACRYOCYSTITIS FOR NEWBORNS

2021 ◽  
pp. 29-32
Author(s):  
У.М. ТИЛЕКЕЕВА ◽  
Т.Б. УСКЕНБАЕВ

В работе изучена антимикробная терапии дакриоцистита новорожденных, на основе анализа микробного пейзажа возбудителей, их чувствительности к антимикробным препаратам. По степени поражения и по возрастные группам, наиболее часто - 44% эта патология поражала 3-6 месячных младенцев, на втором месте пациенты от 0 до 3х месяцев - 33%, на третьем 6-9 месячные - 19%, на четвертом 9-12 месячные дети 4%. Бактериологический посев 46 образцов выявил отсутствие роста микрофлоры в 8 результатах. Микробный пейзаж в 38 мазках включал 10 возбудителей дакриоцистита новорожденных, наиболее часто высевались St. Еpidermidis и St. Aureus, моноинфекция обнаружена в биоматериале 30 глаз, микстифекция в 8. Наибольшую чувствительность по 84% пораженных глаз актуальные возбудители проявили к фторхинолонам последнего поколения: левофлоксацину и моксифлоксацину, к гентамицину 76,5%, фузидоевой кислоте, ципрофлаксацину по 68,5% глаз к каждому, к тобрамицину 58% глаз. Наименьшую, менее 50% чувствительность в отношении вышеуказанных возбудителей ДН показали офлоксацин и левомицетин. Antimicrobial therapy for dacryocystitis for newborns, was studied in the work, based on the analysis of the microbial landscape of pathogens, their sensitivity to antimicrobial drugs. By the degree of damage and by age groups, most often - 44% this pathology affected 3-6 month old babies, in second place are patients from 0 to 3 months - 33%, in the third 6-9 months - 19%, in the fourth - 9-12 monthly children 4%. Bacteriological inoculation of 46 samples showed no growth of microflora in 8 results. The microbial landscape in 38 smears included 10 pathogens of neonatal dacryocystitis, most often St. Epidermidis and St. Aureus, monoinfection was found in the biomaterial of 30 eyes, mixed infection in 8. Topical pathogens showed the greatest sensitivity in 84% of the affected eyes to the latest generation of fluoroquinolones: levofloxacin and moxifloxacin, to gentamicin 76.5%, fusidoic acid, ciproflaxacin in 68.5% of each eye, and to tobramycin in 58% of the eyes. Ofloxacin and chloramphenicol showed the smallest, less than 50% sensitivity to the above mentioned DN pathogens.

Author(s):  
Paul W Turke

Abstract The severity of COVID-19 is age-related, with the advantage going to younger age groups. Five reasons are presented. The first two are well-known, are being actively researched by the broader medical community, and therefore are discussed only briefly here. The third, fourth, and fifth reasons derive from evolutionary life history theory, and potentially fill gaps in current understanding of why and how young and old age groups respond differently to infection with SARS-CoV-2. Age of onset of generalized somatic aging, and the timing of its progression, are identified as important causes of these disparities, as are specific antagonistic pleiotropic tradeoffs in immune system function.


Author(s):  
Hisham Ahmed Moheeb ◽  
Mansoor Al-Tauqi ◽  
Khalifa Bin Mubarak Al Jadeedi

This study aimed to identify the anaerobic capacity level of a sample of Omani children. The sample included 197 children between the ages of 9 to 13 years. The Running-based Anaerobic Sprint Test (RAST) was used. The sample was divided into five groups. The first group comprised the nine-year olds (19 children), the second group comprised the ten-year olds (22 children), the third group comprised the eleven-year olds (52 children), the fourth group comprised the 12-year olds (43 children), and the fifth comprised the 13-year olds (61 children). The results showed that the anaerobic capacity level improved during the stages of growth. The level of improvement achieved in 13-year old children was the highest compared to the other age-groups (P S 0.000). This improvement was not at a steady rate. It occurred through booms that coincided with growth which appears in practice through the evolution of not only the level of values on the amount of effort, but also in the level of some related motor skills. It showed a positive correlation between the values of the anaerobic capacity level, the time of running 100 meters and vertical jumping (p S 0.01). Accordingly, this phase can be considered one of those booms. Key words: anaerobic capacity, (Running-based Anaerobic Sprint Test (RAST), Omani children, the 100 meters running, vertical jumping.


2016 ◽  
Vol 18 (3(71)) ◽  
pp. 182-185
Author(s):  
A.A. Fotina ◽  
Zh.E. Klischova

The using of antibiotics and antimicrobials drugs without control may leads to the development of numerous complications and resistance of microorganisms to antibiotics. The using of antibiotics and antimicrobials drugs should are controlled on poultry farms. That is why the monitoring and determination of sensitivity of bacterial diseases agents to antimicrobial drugs are very important. Results of salmonellas’ and kolibakterias’ monitoring in poultry’s farms of Ukraine are introduced in the article. Researches were conducted at the Department of veterinary sanitary examination, microbiology, zoohygiene and safety and quality of livestock products of Sumy NAU. Sampling for microbiological studies was conducted from the hatchery and from pathological material and premises where poultry of different age groups was held. The spread of the disease, morbidity, mortality, mortality rate, age characteristics, economic loss what diseases cause to the poultry farms were counted. Identification of Salmonella and Escherichia was conducted by ELISA with using of RIDASCREEN® and LOCATE® test systems, according to methodical recommendations of RIDASCREEN® and LOCATE® test systems using. The results were read visually or after addition of storageco with ELISA–photometer (reader) at 450 nm. Sensitivity to antibiotics was determined by disco – diffusion method in agar. Microbiological monitoring of a number of poultry farms in Ukraine has shown that agents of bacterial diseases’ are widely spread. Between the isolated microflora largest number were accounted for Salmonella (54.1%) and the Escherichia (30.8 per cent). The rest (15,1%) were isolated cultures of Proteus, Pseudomonas, Klebsiella, Salmonella, Campylobacteria, Enterobacteria, and Clostridia Citrobacter. This indicates that systematic control over the availability of the causative agents of bacterial infections in all critical points of production of poultry products is very necessary. Among isolates that were isolated from ill poultry and poultry objects, differences in their sensitivity to antimicrobial agents from active substances that officially have registered in our country were discovered. Bactericidal activity of relatively isolated cultures was showed by colistin, ftorfenicol, zeftiocur, TimTil 250, doxicyclin, enroxil and sarafloxacin.  


2008 ◽  
Vol 5 (2) ◽  
pp. 243-248
Author(s):  
Baghdad Science Journal

Age and growth of Varicorhinus damascinus (Val.) in Tigris river at Salahuldin province have been investigated. Monthly samples were taken during the period from September 1999 to August 2000, using small-meshed gill nets. The age data showed that there were six age groups and the dominant age groups were (III – IV) for both sexes. The results of the present study revealed that the increment in length of V. damascinus at the sites of study showed a tendency to decrease with the increase in age, after the third year of life in both sexes. The length-weight relationship of males and females were calculated and demonstrated in a straight line logarithmic formula, as follows: Log W = 1.5404 + 2.6885 log L for males r = 0.95 (P > 0.05) Log W = 1.6723 + 2.7877 log L for females r = 0.77 (P > 0.05) The values of the regression coefficient (b) indicated that the growth of both sexes of V. damascinus was allometric..


2020 ◽  
Vol 5 (2) ◽  
pp. 99-104
Author(s):  
Evgenii L. Borschuk ◽  
Dmitrii N. Begun ◽  
Tatyana V. Begun

Objectives - to study the mortality indicators, their dynamics and structure, in the population of the Orenburg region in the period of 2011-2017. Material and methods. The study was conducted using the data from the territorial authority of statistics in the Orenburg region in the period from 2011 to 2017. The analytical, demographic and statistical methods were implemented for the study of the demographic indicators. Results. Cities and municipal settlements of the Orenburg region with high mortality indicators were included in the second and fourth clusters during the cluster analysis. The first and third clusters included cities and municipal settlements with an average mortality. The most favorable position has the Orenburg area with the lowest mortality rate in the region in 2017 - 8.4%. The dynamics of mortality rates among the male and female population tends to decrease, more pronounced dynamics is in men. Though, the male population is characterized by higher mortality rates in all age groups. The leading position among the causes of death is taken by diseases of the circulatory system (46.3% of the total mortality). The second position is occupied by tumors (17.2%), the third - by external causes (8.4%). Mortality from circulatory system diseases and from external causes has reduced. The dynamics of mortality from tumors does not change significantly. The rank of leading causes of death is not identical in the clusters: in the third and fourth clusters, the other causes occupy the second place in the structure of mortality, while tumors occupy the third. Conclusion. In the Orenburg region, the mortality rate is higher than overage in the Russian Federation by 0.9 per 1000 people. The study revealed significant territorial differences in the mortality rates. In general, the mortality among men in all age groups is higher than the mortality of women. The mortality rate from diseases of the circulatory system plays the leading role in the structure of mortality, but has the tendency for decline. Until 2006, the mortality from external causes ranked the second place, now the second place is taken by death from tumors The mortality from external causes is decreasing; mortality from tumors does not change significantly. The obtained results could be used by local authorities in developing the program of public health protection and assessing its effectiveness.


1970 ◽  
Vol 60 (1) ◽  
pp. 67-78 ◽  
Author(s):  
G. V. Sumner

It is generally recognized that Rome of the early Republic offers a good example of the correlation between military and political organization. The ordering of the Roman citizenry in centuries, classes and age-groups was in origin and essence a military system. The Comitia Centuriata was the exercitus urbanus—the army on parade in the Field of Mars.But by the third century B.C. the Roman army and the centuriate assembly were manifestly two different systems, even if vestiges of their interconnection lingered on. The process whereby this differentiation had come about is, unfortunately, not so clear. The traditional accounts of early Roman history generally failed to devote much attention to questions of that order. Yet the effort to tackle and, if possible, solve this complex of problems can hardly be evaded. The answers given, or assumed, by modern historians are bound to determine how the whole history of early Rome is interpreted and represented.


2019 ◽  
Vol 70 ◽  
pp. 06011
Author(s):  
Anatoly P. Smantser ◽  
Tatiana A. Sidorchuk ◽  
Мaria А. Sidorchuk

The article deals with the features of intergenerational interaction of students of different ages within a single educational environment and an ambiguous attitude to the social and psychological experience of generations. Empirical research has shown that within the framework of a gerontological unit all age groups of students have an opportunity to receive a qualitatively new social experience on a permanent basis in professional, cultural, leisure and volunteer fields. It should be noted that the younger generation has a positive attitude to retro students; they want to and can become retro students’ mentors, helping the elderly to master modern competencies. Retro students, despite the difficulties of interpersonal relations, are ready as mentors to share their knowledge, social and life experiences with young people. The results presented in the article have shown that the most promising forms of cooperation between students and retro-students are master classes in various areas, and creation of gerontological faculties at universities is the strategic direction of gerontology education.


2017 ◽  
Vol 3 (3) ◽  
pp. 352-356
Author(s):  
Prokash Biswas ◽  
Md Bahanur Rahman ◽  
Sayra Tasnin Sharmy ◽  
Md Ferdousur Rahman Khan ◽  
Md Mizanur Rahman ◽  
...  

The present study was carried out to determine the prevalence of bovine and avian tuberculosis in cattle by using bovine and avian PPDs at Bangladesh Livestock Research Institute (BLRI) Cattle Farm, Savar, Dhaka. Cattle of different breeds, ages and sexes (n=183) were tested using bovine and avian PPDs. In caudal Fold Tuberculin (CFT) test, 16 (8.74%) cases were showed positive reaction among 183 sample. The overall percentages of positive reactors to Comparative cervical tuberculin (CCT) test of bovine and avian tuberculosis were 7.10% and 1.64% respectively. An insignificant variation (P>0.05) on prevalence of bovine tuberculosis on different age group of cattle was observed. Age group >7 years showed a higher prevalence (10.91%) than those of other age groups. In CCT test, 7.55% and 4.17% positive reactors were found in female and male cattle respectively. The association between different breeds of the animal was found significant (P<0.05). The local breed showed higher prevalence (9.77%) than those of Red Chittagong and cross breed. The highest percentage (10.45%) of positive reactors in CCT test was recorded in milking cows than in dry cows (2.32%), heifer (9.52%) and calf (5.77%) were observed. Mixed infection (bovine and avian type of tuberculosis) was recorded 1.64%.Asian J. Med. Biol. Res. September 2017, 3(3): 352-356


2020 ◽  
Vol 190 (1) ◽  
pp. 100-107
Author(s):  
Aydın Parmaksız ◽  
Gökçe K Ataç ◽  
Emine Bulur ◽  
Tolga İnal ◽  
Aslıhan Alhan

Abstract In order to establish national diagnostic reference levels for mammography examinations, entrance skin air kerma, entrance skin dose and average glandular doses (AGDs) were calculated for a total of 25 624 cranio-caudal (CC) and mediolateral oblique (MLO) projections of 6309 patients for 40–49 and 50–64 age groups. The average entrance skin air kerma and entrance skin dose values for both age groups were found to be higher in MLO projections compared with CC projections. The minimum and maximum values of AGDs were determined as 0.4 and 7.9 mGy for both projections. The maximum numbers of AGDs for CC and MLO projections were calculated in the range of 1.1–1.5 and 1.6–2.0 mGy, respectively. The third quartile values of AGDs were calculated for each compressed breast thickness between 20 and 99 mm. The first national diagnostic reference levels of the country were established for each 10-mm compressed breast thickness in mammography examinations.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Junpei Komagamine ◽  
Taku Yabuki ◽  
Taku Hiraiwa

Abstract Objectives The supply of cefazolin has been reduced dramatically since March 2019 in Japan. However, no studies have evaluated the effects of cefazolin shortage on the appropriateness of antimicrobial use. Therefore, we compared the appropriateness of inpatient antimicrobial drug use between the two surveys conducted in August 2018 and August 2019 in a Japanese hospital with no supply of cefazolin since the cefazolin shortage. Results In the 2019 survey, a total of 275 patients were included, and 256 patients were included in the 2018 survey. The prevalence of antimicrobial drug use did not change from 2018 to 2019 (28.5% versus 28.7%; p = 0.96). The proportion of cefazolin in all antimicrobial drugs used on the survey date significantly decreased from 2018 to 2019 (24.1% versus 0.0%; p < 0.001). The proportion of appropriate antimicrobial use in all antimicrobial therapies tended to be lower in 2019 than in 2018 (41.2% versus 60.6%; p = 0.06), and the proportion of unnecessary use of a broader spectrum of antimicrobial drugs significantly increased from 2018 to 2019 (4.7% versus 37.3%; p = 0.002). The shortage of cefazolin might lead to inappropriate use of other antimicrobial drugs.


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